Waser, Beatrice; Reubi, Jean-Claude (2011). Value of the radiolabelled GLP-1 receptor antagonist exendin(9-39) for targeting of GLP-1 receptor-expressing pancreatic tissues in mice and humans. European journal of nuclear medicine and molecular imaging, 38(6), pp. 1054-8. Berlin: Springer-Verlag 10.1007/s00259-010-1701-0
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Radiolabelled glucagon-like peptide 1 (GLP-1) receptor agonists have recently been shown to successfully image benign insulinomas in patients. Moreover, it was recently reported that antagonist tracers were superior to agonist tracers for somatostatin and gastrin-releasing peptide receptor targeting of tumours. The present preclinical study determines therefore the value of an established GLP-1 receptor antagonist for the in vitro visualization of GLP-1 receptor-expressing tissues in mice and humans.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Waser, Beatrice, Reubi-Kattenbusch, Jean-Claude |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
1619-7070 |
Publisher: |
Springer-Verlag |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:18 |
Last Modified: |
05 Dec 2022 14:05 |
Publisher DOI: |
10.1007/s00259-010-1701-0 |
PubMed ID: |
21210113 |
Web of Science ID: |
000290574100009 |
BORIS DOI: |
10.7892/boris.5564 |
URI: |
https://boris.unibe.ch/id/eprint/5564 (FactScience: 210318) |
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