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Karamitopoulou, Eva; Wenning, Anna Silvia; Acharjee, Animesh; Aeschbacher, Pauline; Marinoni, Ilaria; Zlobec, Inti; Gloor, Beat; Perren, Aurel (2024). Spatial heterogeneity of immune regulators drives dynamic changes of local immune responses, affecting disease outcomes in pancreatic cancer. (In Press). Clinical cancer research American Association for Cancer Research 10.1158/1078-0432.CCR-24-0368
Chouchane, Aziz; Kirchner, Philipp; Marinoni, Ilaria; Sticová, Eva; Jirásek, Tomáš; Perren, Aurel (2024). Pancreatic Neuroendocrine Microtumors (WHO 2022) Are Not Always Low-Grade Neoplasms: A Case with a Highly Increased Proliferation Rate. Endocrine pathology, 35(2), pp. 147-153. Springer 10.1007/s12022-024-09802-7
April-Monn, Simon L; Kirchner, Philipp; Detjen, Katharina; Bräutigam, Konstantin; Trippel, Mafalda A; Grob, Tobias; Statzer, Cyril; Maire, Renaud S; Kollár, Attila; Chouchane, Aziz; Kunze, Catarina A; Horst, David; Sadowski, Martin C; Schrader, Jörg; Marinoni, Ilaria; Wiedenmann, Bertram; Perren, Aurel (2024). Patient derived tumoroids of high grade neuroendocrine neoplasms for more personalized therapies. NPJ precision oncology, 8(59) Springer Nature 10.1038/s41698-024-00549-2
Gulde, Sebastian; Foscarini, Alessia; April-Monn, Simon L; Genio, Edoardo; Marangelo, Alessandro; Satam, Swapna; Helbling, Daniel; Falconi, Massimo; Toledo, Rodrigo A; Schrader, Jörg; Perren, Aurel; Marinoni, Ilaria; Pellegata, Natalia S (2022). Combined Targeting of Pathogenetic Mechanisms in Pancreatic Neuroendocrine Tumors Elicits Synergistic Antitumor Effects. Cancers, 14(22) MDPI AG 10.3390/cancers14225481
Depoilly, Thomas; Leroux, Raffaele; Andrade, Dafne; Nicolle, Remy; Dioguardi Burgio, Marco; Marinoni, Ilaria; Dokmak, Safi; Ruszniewski, Philippe; Hentic, Olivia; Paradis, Valérie; De Mestier, Louis; Perren, Aurel; Couvelard, Anne; Cros, Jérôme (2022). Immunophenotypic and molecular characterization of pancreatic neuroendocrine tumors producing serotonin. Modern pathology, 35(11), pp. 1713-1722. Springer Nature 10.1038/s41379-022-01110-x
Battistella, Anna; Partelli, Stefano; Andreasi, Valentina; Marinoni, Ilaria; Palumbo, Diego; Tacelli, Matteo; Lena, Marco Schiavo; Muffatti, Francesca; Mushtaq, Junaid; Capurso, Gabriele; Arcidiacono, Paolo Giorgio; De Cobelli, Francesco; Doglioni, Claudio; Perren, Aurel; Falconi, Massimo (2022). Preoperative assessment of microvessel density in nonfunctioning pancreatic neuroendocrine tumors (NF-PanNETs). Surgery, 172(4), pp. 1236-1244. Elsevier 10.1016/j.surg.2022.06.017
Marinoni, Ilaria (2022). Prognostic value of DAXX/ATRX loss of expression and ALT activation in PanNETs: is it time for clinical implementation? Gut, 71(5), pp. 847-848. BMJ Publishing Group 10.1136/gutjnl-2021-324664
Simon, Tincy; Riemer, Pamela; Jarosch, Armin; Detjen, Katharina; Di Domenico, Annunziata; Bormann, Felix; Menne, Andrea; Khouja, Slim; Monjé, Nanna; Childs, Liam H; Lenze, Dido; Leser, Ulf; Rossner, Florian; Morkel, Markus; Blüthgen, Nils; Pavel, Marianne; Horst, David; Capper, David; Marinoni, Ilaria; Perren, Aurel; ... (2022). DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors. Genome medicine, 14(1), p. 24. BioMed Central 10.1186/s13073-022-01018-w
April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014
Saghafinia, Sadegh; Homicsko, Krisztian; Di Domenico, Annunziata; Wullschleger, Stephan; Perren, Aurel; Marinoni, Ilaria; Ciriello, Giovanni; Michael, Iacovos P; Hanahan, Douglas (2021). Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression. Cancer discovery, 11(10), pp. 2638-2657. American Association for Cancer Research 10.1158/2159-8290.CD-20-1637
Rinke, Anja; Auernhammer, Christoph J; Bodei, Lisa; Kidd, Mark; Krug, Sebastian; Lawlor, Rita; Marinoni, Ilaria; Perren, Aurel; Scarpa, Aldo; Sorbye, Halfdan; Pavel, Marianne Ellen; Weber, Matthias M; Modlin, Irvin; Gress, Thomas M (2021). Treatment of advanced gastroenteropancreatic neuroendocrine neoplasia, are we on the way to personalised medicine? Gut, 70(9), pp. 1768-1781. BMJ Publishing Group 10.1136/gutjnl-2020-321300
Bräutigam, Konstantin; Rodríguez-Calero, Antonio; Kim-Fuchs, Corina; Kollár, Attila; Trepp, Roman; Marinoni, Ilaria; Perren, Aurel (2021). Update on Histological Reporting Changes in Neuroendocrine Neoplasms. Current Oncology Reports, 23(6), p. 65. Springer 10.1007/s11912-021-01062-6
April-Monn, Simon Leonhard; Wiedmer, Tabea; Skowronska, Magdalena; Maire, Renaud; Schiavo Lena, Marco; Trippel, Mafalda; Di Domenico, Annunziata; Muffatti, Francesca; Andreasi, Valentina; Capurso, Gabriele; Doglioni, Claudio; Kim-Fuchs, Corina; Gloor, Beat; Zatelli, Maria Chiara; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). 3D Primary Cell Culture: A Novel Preclinical Model For Pancreatic Neuroendocrine Tumors (PanNETs). Neuroendocrinology, 111(3), pp. 273-287. Karger 10.1159/000507669
Di Domenico, Annunziata; Pipinikas, Christodoulos P; Maire, Renaud S; Bräutigam, Konstantin; Simillion, Cedric; Dettmer, Matthias S; Vassella, Erik; Thirlwell, Chrissie; Perren, Aurel; Marinoni, Ilaria (2020). Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression. Communications biology, 3(1), p. 740. Springer Nature 10.1038/s42003-020-01479-y
Boos, Laura A; Schmitt, Anja; Moch, Holger; Komminoth, Paul; Simillion, Cedric; Marinoni, Ilaria; Nikiforov, Yuri E; Nikiforova, Marina N; Perren, Aurel; Dettmer, Matthias S. (2019). MiRNAs Are Involved in Tall Cell Morphology in Papillary Thyroid Carcinoma. Cancers, 11(6) MDPI AG 10.3390/cancers11060885
Michael, Iacovos P; Saghafinia, Sadegh; Tichet, Mélanie; Zangger, Nadine; Marinoni, Ilaria; Perren, Aurel; Hanahan, Douglas (2019). ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis. Developmental cell, 49(3), 409-424.e6. Cell Press 10.1016/j.devcel.2019.04.015
Rindi, Guido; Klersy, Catherine; Albarello, Luca; Baudin, Eric; Bianchi, Antonio; Büchler, Markus W; Caplin, Martyn; Couvelard, Anne; Cros, Jérôme; de Herder, Wouter W; Delle Fave, Gianfranco; Doglioni, Claudio; Federspiel, Birgitte; Fischer, Lars; Fusai, Giuseppe; Gavazzi, Francesca; Hansen, Carsten; Inzani, Frediano; Jann, Henning; Komminoth, Paul; ... (2018). COMPETITIVE TESTING THE WHO 2010 VS THE WHO 2017 GRADING OF PANCREAS NEUROENDOCRINE NEOPLASIA: DATA FROM A LARGE INTERNATIONAL COHORT STUDY. Neuroendocrinology, 107(4), pp. 375-386. Karger 10.1159/000494355
Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136
Di Domenico, Annunziata; Wiedmer, Tabea; Marinoni, Ilaria; Perren, Aurel (2017). Genetic and epigenetic drivers of neuroendocrine tumours (NET). Endocrine-related cancer, 24(9), R315-R334. BioScientifica Ltd. 10.1530/ERC-17-0012
Marinoni, Ilaria; Wiederkehr, Astrid; Wiedmer, Tabea; Pantasis, Sophia; Di Domenico, Annunziata; Rasmus Möller, Frank; Vassella, Erik; Schmitt Kurrer, Anja; Perren, Aurel (2017). Hypo-methylation mediates chromosomal instability in pancreatic NET. Endocrine-related cancer, 24(3), pp. 137-146. BioScientifica Ltd. 10.1530/ERC-16-0554
Falletta, Simona; Partelli, Stefano; Rubini, Corrado; Nann, Dominik; Doria, Andrea; Marinoni, Ilaria; Polenta, Vanessa; Di Pasquale, Carmelina; Degli Uberti, Ettore; Perren, Aurel; Falconi, Massimo; Zatelli, Maria Chiara (2016). mTOR inhibitors response and mTOR pathway in pancreatic neuroendocrine tumors. Endocrine-related cancer, 23(11), pp. 883-891. BioScientifica Ltd. 10.1530/ERC-16-0329
Schmitt Kurrer, Anja; Marinoni, Ilaria; Blank, Annika; Perren, Aurel (2016). New Genetics and Genomic Data on Pancreatic Neuroendocrine Tumors: Implications for Diagnosis, Treatment, and Targeted Therapies. Endocrine pathology, 27(3), pp. 200-204. Springer 10.1007/s12022-016-9447-2
Schmitt Kurrer, Anja; Blank, Annika; Marinoni, Ilaria; Komminoth, Paul; Perren, Aurel (2016). Histopathology of NET: Current concepts and new developments. Best practice & research. Clinical endocrinology & metabolism, 30(1), pp. 33-43. Elsevier 10.1016/j.beem.2016.02.002
Brügger, Fabienne; Dettmer, Matthias; Neuenschwander, Maja; Perren, Aurel; Marinoni, Ilaria; Hewer, Ekkehard (2016). TERT Promoter Mutations but not the Alternative Lengthening of Telomeres Phenotype Are Present in a Subset of Ependymomas and Are Associated With Adult Onset and Progression to Ependymosarcoma. Journal of neuropathology and experimental neurology, 76(1), pp. 61-66. Oxford University Press 10.1093/jnen/nlw106
Blank, Annika; Wehweck, Laura; Marinoni, Ilaria; Boos, Laura Amanda Meret Sophie; Bergmann, Frank; Schmitt Kurrer, Anja; Perren, Aurel (2015). Interlaboratory variability of MIB1 staining in well-differentiated pancreatic neuroendocrine tumors. Virchows Archiv, 467(5), pp. 543-550. Springer 10.1007/s00428-015-1843-3
Marinoni, Ilaria; Schmitt Kurrer, Anja; Vassella, Erik; Dettmer, Matthias; Rudolph, Thomas; Banz, Vanessa Martine; Hunger, Fabio; Pasquinelli, Silvan; Speel, Ernst-Jan; Perren, Aurel (2014). Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors. Gastroenterology, 146(2), 453-460.e5. Elsevier 10.1053/j.gastro.2013.10.020
Marinoni, Ilaria; Lee, Misu; Mountford, Steffeni; Perren, Aurel; Bravi, Ilaria; Jennen, Louise; Feuchtinger, Annette; Drouin, Jacques; Roncaroli, Federico; Pellegata, Natalia S (2012). Characterization of MENX-associated pituitary tumours. Neuropathology & applied neurobiology, 39(3), pp. 256-269. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2990.2012.01278.x
Miederer, Matthias; Molatore, Sara; Marinoni, Ilaria; Perren, Aurel; Spitzweg, Christine; Reder, Sybille; Wester, Hans-Jürgen; Buck, Andreas K; Schwaiger, Markus; Pellegata, Natalia S (2011). Functional Imaging of Pheochromocytoma with Ga-DOTATOC and C-HED in a Genetically Defined Rat Model of Multiple Endocrine Neoplasia. International journal of molecular imaging, 2011, p. 175352. New York, N.Y.: Hindawi 10.1155/2011/175352
