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Radpour, Ramin; Simillion, Cedric; Wang, Bofei; Abbas, Hussein A; Riether, Carsten; Ochsenbein, Adrian (2024). IL-9 Secreted by Leukemia Stem Cells Induces Th1-Skewed CD4+ T-Cells, which Promote Their Expansion. Blood, 144(8), pp. 888-903. American Society of Hematology 10.1182/blood.2024024000
Mandhair, Harpreet K; Radpour, Ramin; Westerhuis, Mira; Banz, Yara; Humbert, Magali; Arambasic, Miroslav; Dengjel, Jörn; Davies, Andrew; Tschan, Mario P; Novak, Urban (2024). Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach. Leukemia, 38(2), pp. 424-429. Nature Publishing Group 10.1038/s41375-024-02147-4
Naef, Pascal; Radpour, Ramin; Jaeger-Ruckstuhl, Carla A; Bodmer, Nils; Baerlocher, Gabriela M; Doehner, Hartmut; Doehner, Konstanze; Riether, Carsten; Ochsenbein, Adrian F (2023). IL-33-ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways. Science signaling, 16(800), eadd7705. 10.1126/scisignal.add7705
Forster, Stefan; Radpour, Ramin; Ochsenbein, Adrian F (2023). Molecular and immunological mechanisms of clonal evolution in multiple myeloma. Frontiers in immunology, 14(1243997), p. 1243997. Frontiers Research Foundation 10.3389/fimmu.2023.1243997
Bührer, Elias D; Amrein, Michael A; Forster, Stefan; Isringhausen, Stephan; Schürch, Christian M; Bhate, Salil S; Brodie, Tess; Zindel, Joel; Stroka, Deborah; Al Sayed, Mohamad; Nombela-Arrieta, César; Radpour, Ramin; Riether, Carsten; Ochsenbein, Adrian F (2022). Splenic red pulp macrophages provide a niche for CML stem cells and induce therapy resistance. Leukemia, 36(11), pp. 2634-2646. Springer Nature 10.1038/s41375-022-01682-2
Forster, Stefan; Radpour, Ramin (2022). Molecular Impact of the Tumor Microenvironment on Multiple Myeloma Dissemination and Extramedullary Disease. Frontiers in oncology, 12, p. 941437. Frontiers Research Foundation 10.3389/fonc.2022.941437
Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w
Hinterbrandner, Magdalena; Rubino, Viviana; Stoll, Carina; Forster, Stefan; Schnüriger, Noah Samuel; Radpour, Ramin; Bärlocher, Gabriela M.; Ochsenbein, Adrian F.; Riether, Carsten (2021). Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells. JCI insight, 6(23) JCI Insight 10.1172/jci.insight.151797
Mandhair, Harpreet K; Novak, Urban; Radpour, Ramin (2021). Epigenetic regulation of autophagy: A key modification in cancer cells and cancer stem cells. World journal of stem cells, 13(6), pp. 542-567. Baishideng Publishing Group 10.4252/wjsc.v13.i6.542
Höpner, S. S.; Raykova, Ana; Radpour, R.; Amrein, M. A.; Koller, D.; Bärlocher, G. M.; Riether, C.; Ochsenbein, A. F. (2021). LIGHT/LTβR signaling regulates self-renewal and differentiation of hematopoietic and leukemia stem cells. Nature Communications, 12(1), p. 1065. Springer Nature 10.1038/s41467-021-21317-x
Riether, Carsten; Radpour, Ramin; Kallen, Nils M.; Bürgin, Damian T.; Bachmann, Chantal; Schürch, Christian M.; Lüthi, Ursina; Arambasic, Miroslav; Hoppe, Sven; Albers, Christoph E.; Baerlocher, Gabriela M.; Ochsenbein, Adrian (2021). Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells. Cell reports, 34(4), p. 108663. Cell Press 10.1016/j.celrep.2020.108663
Radpour, Ramin; Stucki, Miriam; Riether, Carsten; Ochsenbein, Adrian F. (2021). Epigenetic Silencing of Immune-Checkpoint Receptors in Bone Marrow- Infiltrating T Cells in Acute Myeloid Leukemia. Frontiers in oncology, 11, p. 663406. Frontiers Research Foundation 10.3389/fonc.2021.663406
Negahdari, Samira; Zamani, Mina; Seifi, Tahereh; Sedighzadeh, Sahar; Mazaheri, Neda; Zeighami, Jawaher; Sedaghat, Alireza; Saberi, Alihossein; Hamid, Mohammad; Keikhaei, Bijan; Radpour, Ramin; Shariati, Gholamreza; Galehdari, Hamid (2020). Identification of Three Novel Mutations in the FANCA, FANCC, and ITGA2B Genes by Whole Exome Sequencing. International journal of preventive medicine, 11(117), p. 117. 10.4103/ijpvm.IJPVM_462_19
Mandhair, Harpreet K.; Arambasic, Miroslav; Novak, Urban; Radpour, Ramin (2020). Molecular modulation of autophagy: New venture to target resistant cancer stem cells. World journal of stem cells, 12(5), pp. 303-322. 10.4252/wjsc.v12.i5.303
Jaeger-Ruckstuhl, Carla A.; Hinterbrandner, Magdalena; Höpner, Sabine; Correnti, Colin E; Lüthi, Ursina; Friedli, Olivier; Freigang, Stefan; Al Sayed, Mohamad F; Bührer, Elias D.; Amrein, Michael A.; Schürch, Christian M.; Radpour, Ramin; Riether, Carsten; Ochsenbein, Adrian F. (2020). TNIK signaling imprints CD8+ T cell memory formation early after priming. Nature communications, 11(1), p. 1632. Nature Publishing Group 10.1038/s41467-020-15413-7
Forster, Stefan; Radpour, Ramin (2020). Molecular Immunotherapy: Promising Approach to Treat Metastatic Colorectal Cancer by Targeting Resistant Cancer Cells or Cancer Stem Cells. Frontiers in oncology, 10, p. 569017. Frontiers Research Foundation 10.3389/fonc.2020.569017
Al Sayed, M; Amrein, Martin Lukas; Bührer, Emanuel; Huguenin, AL; Radpour, Ramin; Riether, Carsten; Ochsenbein, Adrian (2019). T-cell-Secreted TNFα Induces Emergency Myelopoiesis and Myeloid-Derived Suppressor Cell Differentiation in Cancer. Cancer research, 79(2), pp. 346-359. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-17-3026
Radpour, Ramin; Riether, Carsten; Simillion, Cedric; Höpner, Sabine; Bruggmann, Rémy; Ochsenbein, Adrian (2019). CD8+ T cells expand stem and progenitor cells in favorable but not adverse risk acute myeloid leukemia. Leukemia, 33(10), pp. 2379-2392. Nature Publishing Group 10.1038/s41375-019-0441-9
Burkhard, Regula; Keller, Irene; Arambasic, Miroslav; Juskevicius, Darius; Tzankov, Alexandar; Lundberg, Pontus; Bruggmann, Rémy; Dirnhofer, Stephan; Radpour, Ramin; Novak, Urban (2019). TIRAP p.R81C is a novel lymphoma risk variant which enhances cell proliferation via NF-κB mediated signaling in B-cells. Haematologica - the hematology journal, 104(4), pp. 766-777. Ferrata-Storti Foundation 10.3324/haematol.2018.201590
Radpour, Ramin; Forouharkhou, Farzad (2018). Single-cell analysis of tumors: Creating new value for molecular biomarker discovery of cancer stem cells and tumor-infiltrating immune cells. World journal of stem cells, 10(11), pp. 160-171. Baishideng Publishing Group 10.4252/wjsc.v10.i11.160
Radpour, Ramin (2017). Tracing and targeting cancer stem cells: New venture for personalized molecular cancer therapy. World journal of stem cells, 9(10), pp. 169-178. Baishideng Publishing Group 10.4252/wjsc.v9.i10.169
Aghagolzadeh, Parisa; Radpour, Ramin; Bachtler, Matthias; van Goor, Harry; Smith, Edward R; Lister, Adam; Odermatt, Alex; Feelisch, Martin; Pasch, Andreas (2017). Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation. Atherosclerosis, 265, pp. 78-86. Elsevier 10.1016/j.atherosclerosis.2017.08.012
Murone, Maximilien; Radpour, Ramin; Attinger, Antoine; Chessex, Anne Vaslin; Huguenin, Anne-Laure; Schürch, Christian M; Banz Wälti, Yara; Sengupta, Saumitra; Aguet, Michel; Rigotti, Stefania; Bachhav, Yogeshwar; Massière, Frédéric; Ramachandra, Murali; McAllister, Andres; Riether, Carsten (2017). The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34+ Stem/Progenitor Cells. Molecular cancer therapeutics, 16(8), pp. 1497-1510. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-16-0889
Al Sayed, Mohamad; Ruckstuhl, Carla Alicia; Hilmenyuk, Tamara; Claus, Christina; Bourquin, Jean-Pierre; Bornhauser, Beat C; Radpour, Ramin; Riether, Carsten; Ochsenbein, Adrian (2017). CD70 reverse signaling enhances NK cell function and immunosurveillance in CD27-expressing B-cell malignancies. Blood, 130(3), pp. 297-309. American Society of Hematology 10.1182/blood-2016-12-756585
Riether, Carsten; Schürch, Christian M.; Bührer, Elias D.; Hinterbrandner, Magdalena; Huguenin, Anne-Laure; Höpner, Sabine; Zlobec, Inti; Pabst, Thomas; Radpour, Ramin; Ochsenbein, Adrian F. (2017). CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia. The Journal of experimental medicine, 214(2), pp. 359-380. Rockefeller Univ. Press 10.1084/jem.20152008
Riether, Carsten; Schürch, Christian; Flury, Christoph; Hinterbrandner, Magdalena; Drück, Linda; Huguenin, Anne-Laure; Baerlocher, Gabriela M.; Radpour, Ramin; Ochsenbein, Adrian (2015). Tyrosine kinase inhibitor-induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt signaling. Science translational medicine, 7(298), 298ra119. American Association for the Advancement of Science 10.1126/scitranslmed.aab1740
