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Rodrigues, Filipe E P; Darbre, Tamis; Machuqueiro, Miguel (2024). High Charge Density in Peptide Dendrimers is Required to Destabilize Membranes: Insights into Endosome Evasion. Journal of chemical information and modeling, 64(8), pp. 3430-3442. American Chemical Society 10.1021/acs.jcim.4c00018
Bloch, Joël S; John, Alan; Mao, Runyu; Mukherjee, Somnath; Boilevin, Jérémy; Irobalieva, Rossitza N; Darbre, Tamis; Scott, Nichollas E; Reymond, Jean-Louis; Kossiakoff, Anthony A; Goddard-Borger, Ethan D; Locher, Kaspar P (2023). Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nature chemical biology, 19(5), pp. 575-584. Springer Nature 10.1038/s41589-022-01219-9
Eyring, Jillianne; Lin, Chia-Wei; Ngwa, Elsy Mankah; Boilevin, Jérémy; Pesciullesi, Giorgio; Locher, Kaspar P.; Darbre, Tamis; Reymond, Jean-Louis; Aebi, Markus (2021). Substrate specificities and reaction kinetics of the yeast oligosaccharyltransferase isoforms. Journal of biological chemistry, 296, p. 100809. American Society for Biochemistry and Molecular Biology 10.1016/j.jbc.2021.100809
Daralnakhla, Haneen; Saher, Osama; Zamolo, Susanna; Bazaz, Safa; P. Bost, Jeremy; Heitz, Marc; Lundin, Karin E.; EL Andaloussi, Samir; Darbre, Tamis; Reymond, Jean-Louis; Zain, Rula; Smith, C. I. Edvard (2021). Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides. Pharmaceutics, 13(1), p. 116. MDPI 10.3390/pharmaceutics13010116
Bloch, Joël S.; Pesciullesi, Giorgio; Boilevin, Jérémy; Nosol, Kamil; Irobalieva, Rossitza N.; Darbre, Tamis; Aebi, Markus; Kossiakoff, Anthony A.; Reymond, Jean-Louis; Locher, Kaspar P. (2020). Structure and mechanism of the ER-based glucosyltransferase ALG6. Nature, 579(7799), pp. 443-447. Springer Nature 10.1038/s41586-020-2044-z
Zamolo, Susanna J.; Darbre, Tamis; Reymond, Jean-Louis (2020). Transfecting tissue models with CRISPR/Cas9 plasmid DNA using peptide dendrimers. Chemical communications, 56(80), pp. 11981-11984. Royal Society of Chemistry 10.1039/D0CC04750C
Baeriswyl, Stéphane; Gan, Bee Ha; Siriwardena, Thissa N.; Visini, Ricardo; Robadey, Maurane; Javor, Sacha; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2019). X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS Chemical Biology, 14(4), pp. 758-766. American Chemical Society 10.1021/acschembio.9b00047
Heitz, Marc; Javor, Sacha; Darbre, Tamis; Reymond, Jean-Louis (2019). Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection. Bioconjugate chemistry, 30(8), pp. 2165-2182. American Chemical Society 10.1021/acs.bioconjchem.9b00403
Baeriswyl, Stéphane; Javor, Sacha; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2019). X‐Ray Crystal Structure of a Second‐Generation Peptide Dendrimer in Complex with Pseudomonas aeruginosa Lectin LecB. Helvetica chimica acta, 102(9) Wiley 10.1002/hlca.201900178
Taouai, Marwa; Chakroun, Khouloud; Sommer, Roman; Michaud, Gaelle; Giacalone, David; Ben Maaouia, Mohamed Amine; Vallin-Butruille, Aurélie; Mathiron, David; Abidi, Rym; Darbre, Tamis; Cragg, Peter J.; Mullié, Catherine; Reymond, Jean-Louis; O’Toole, George A.; Benazza, Mohammed (2019). Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Pseudomonas aeruginosa Biofilms. Journal of medicinal chemistry, 62(17), pp. 7722-7738. American Chemical Society 10.1021/acs.jmedchem.9b00481
Gan, Bee Ha; Siriwardena, Thissa N.; Javor, Sacha; Darbre, Tamis; Reymond, Jean-Louis (2019). Fluorescence Imaging of Bacterial Killing by Antimicrobial Peptide Dendrimer G3KL. ACS infectious diseases, 5(12), pp. 2164-2173. American Chemical Society 10.1021/acsinfecdis.9b00299
Napiórkowska, Maja; Boilevin, Jérémy; Darbre, Tamis; Reymond, Jean-Louis; Locher, Kaspar P. (2018). Structure of bacterial oligosaccharyltransferase PglB bound to a reactive LLO and an inhibitory peptide. Scientific Reports, 8(1) Nature Publishing Group 10.1038/s41598-018-34534-0
Saher, Osama; Rocha, Cristina S.J.; Zaghloul, Eman M.; Wiklander, Oscar P.B.; Zamolo, Susanna; Heitz, Marc; Ezzat, Kariem; Gupta, Dhanu; Reymond, Jean-Louis; Zain, Rula; Hollfelder, Florian; Darbre, Tamis; Lundin, Karin E.; EL Andaloussi, Samir; Smith, C.I. Edvard (2018). Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity. European journal of pharmaceutics and biopharmaceutics, 132, pp. 29-40. Elsevier 10.1016/j.ejpb.2018.09.002
Ramírez, Ana S.; Boilevin, Jérémy; Mehdipour, Ahmad Reza; Hummer, Gerhard; Darbre, Tamis; Reymond, Jean-Louis; Locher, Kaspar P. (2018). Structural basis of the molecular ruler mechanism of a bacterial glycosyltransferase. Nature communications, 9(1) Nature Publishing Group 10.1038/s41467-018-02880-2
Siriwardena, Thissa Appuhamilage Nuwan; Stach, Michaela; He, Runze; Gan, Bee Ha; Javor, Sacha; Heitz, Marc; Ma, Lan; Cai, Xiangjun; Chen, Peng; Wei, Dengwen; Li, Hongtao; Ma, Jun; Koehler, Thilo; van Delden, Christian; Darbre, Tamis; Reymond, Jean-Louis (2018). Lipidated Peptide Dendrimers Killing Multidrug Resistant Bacteria. Journal of the American Chemical Society, 140(1), pp. 423-432. American Chemical Society 10.1021/jacs.7b11037
Ramírez, Ana S; Boilevin, Jérémy; Biswas, Rasomoy; Gan, Bee Ha; Janser, Daniel; Aebi, Markus; Darbre, Tamis; Reymond, Jean-Louis; Locher, Kaspar P (2017). Characterization of the single-subunit oligosaccharyltransferase STT3A from Trypanosoma brucei using synthetic peptides and lipid-linked oligosaccharide analogs. Glycobiology, 27(6), pp. 525-535. Oxford University Press 10.1093/glycob/cwx017
Heitz, Marc; Kwok, Albert; Eggimann, GabrielaA.; Hollfelder, Florian; Darbre, Tamis; Reymond, Jean-Louis (2017). Peptide Dendrimer–Lipid Conjugates as DNA and siRNA Transfection Reagents: Role of Charge Distribution Across Generations. CHIMIA, 71(4), pp. 220-225. Schweizerische Chemische Gesellschaft 10.2533/chimia.2017.220
Ramírez, Ana S; Boilevin, Jérémy; Lin, Chia-Wei; Gan, Bee Ha; Janser, Daniel; Aebi, Markus; Darbre, Tamis; Reymond, Jean-Louis; Locher, Kaspar P (2017). Chemo-enzymatic synthesis of lipid-linked GlcNAc2Man5 oligosaccharides using recombinant Alg1, Alg2 and Alg11 proteins. Glycobiology, 27(8), pp. 726-733. Oxford University Press 10.1093/glycob/cwx045
Di Bonaventura, Ivan; Jin, Xian; Visini, Ricardo; Probst, Daniel; Javor, Sacha; Gan, Bee-Ha; Michaud, Gaëlle; Natalello, Antonino; Doglia, Silvia Maria; Köhler, Thilo; van Delden, Christian; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2017). Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms. Chemical Science, 8(10), pp. 6784-6798. The Royal Society of Chemistry 10.1039/C7SC01314K
He, Runze; Di Bonaventura, Ivan; Visini, Ricardo; Gan, Bee-Ha; Fu, Yongchun; Probst, Daniel; Lüscher, Alexandre; Köhler, Thilo; van Delden, Christian; Stocker, Achim; Hong, Wenjing; Darbre, Tamis; Reymond, Jean-Louis (2017). Design, crystal structure and atomic force microscopy study of thioether ligated d , l -cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chemical Science, 8(11), pp. 7464-7475. The Royal Society of Chemistry 10.1039/C7SC01599B
Napiórkowska, Maja; Boilevin, Jérémy; Sovdat, Tina; Darbre, Tamis; Reymond, Jean-Louis; Aebi, Markus; Locher, Kaspar P (2017). Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosaccharyltransferase. Nature structural & molecular biology, 24(12), pp. 1100-1106. Nature Publishing Group 10.1038/nsmb.3491
Michaud, Gaëlle; Visini, Ricardo; Bergman, Manfred Max; Salerno, Gianluca; Bosco, Rosa; Gillon, Emilie; Richichi, Barbara; Nativi, Cristina; Imberty, Anne; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2016). Overcoming antibiotic resistance in Pseudomonas aeruginosa biofilms using glycopeptide dendrimers. Chemical Science, 7(1), pp. 166-182. The Royal Society of Chemistry 10.1039/c5sc03635f
Filipe, Luis C. S.; Machuqueiro, Miguel; Darbre, Tamis; Baptista, Antonio M. (2016). Exploring the Structural Properties of Positively Charged peptide Dendrimers. Journal of physical chemistry - B, 120(43), pp. 11323-11330. American Chemical Society 10.1021/acs.jpcb.6b09156
Filipe, Luis C. S.; Campus, Sara R. R.; Machuqueiro, Miguel; Darbre, Tamis; Baptista, Antonio M. (2016). Structuring Peptide Dendrimers through pH Modulation and Substrate Binding. Journal of physical chemistry - B, 120(38), pp. 10138-10152. American Chemical Society 10.1021/acs.jpcb.6b05905
Kwok, Albert; Eggimann, Gabriela A.; Heitz, Marc; Reymond, Jean-Louis; Hollfelder, Florian; Darbre, Tamis (2016). Efficient Transfection of siRNA by Peptide Dendrimer-Lipid Conjugates. ChemBioChem, 17(23), pp. 2223-2229. Wiley-VCH 10.1002/cbic.201600485
Abdel-Sayed, Philippe; Kaeppli, Ariane; Siriwardena, Thissa; Darbre, Tamis; Perron, Karl; Jafari, Paris; Reymond, Jean-Louis; Pioletti, Dominique P.; Applegate, Lee Ann (2016). Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages. Scientific Reports, 6(22020), p. 22020. Nature Publishing Group 10.1038/srep22020
Pires, João; Siriwardena, Thissa N.; Stach, Michaela; Tinguely, Regula; Kasraian Fard, Sara; Luzzaro, Francesco; Leib, Stephen; Darbre, Tamis; Reymond, Jean-Louis; Endimiani, Andrea (2015). In Vitro Activity of the Novel Antimicrobial Peptide Dendrimer G3KL against Multidrug-Resistant Acinetobacter baumannii and Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 59(12), pp. 7915-7918. American Society for Microbiology 10.1128/AAC.01853-15
Bergman, Manfred Max; Michaud, Gaëlle; Visini, Ricardo; Jin, Xian; Gillon, Emilie; Stocker, Achim; Imberty, Anne; Darbre, Tamis; Reymond, Jean-Louis (2015). Multivalency effects in Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA. Organic & biomolecular chemistry, 14(1), pp. 138-148. Royal Society of Chemistry 10.1039/C5OB01682G
Visini, Ricardo; Bergman, Manfred Max; Michaud, Gaelle; Pertici, Francesca; Fu, Ou; Pukin, Aliaksei; Branson, Thomas; Thies-Weesie, Dominique; Kemmink, Johan; Gillon, Emilie; Imberty, Anne; Stocker, Achim; Darbre, Tamis; Pieters, Roland; Reymond, Jean-Louis (2015). Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeroginosa lectin LecA. ACS Chemical Biology, 10(11), pp. 2455-2462. American Chemical Society 10.1021/acschembio.5b00302
Perez, Camilo; Gerber, Sabina; Boilevin, Jérémy; Bucher, Monika; Darbre, Tamis; Aebi, Markus; Reymond, Jean-Louis; Locher, Kaspar P. (2015). Structure and mechanism of an active lipid-linked oligosaccharide flippase. Nature, 524(7566), pp. 433-438. Macmillan Journals Ltd. 10.1038/nature14953
Bartoloni, Marco; Jin, Xian; Marcaida, Maria José; Banha, João; Di Bonaventura, Ivan; Bongoni, Swathi; Bartho, Kathrin; Gräbner, Olivia; Sefkow, Michael; Darbre, Tamis; Reymond, Jean-Louis (2015). Bridged bicyclic peptides as potential drug scaffolds: synthesis, structure, protein binding and stability. Chemical Science, 6(10), pp. 5473-5490. The Royal Society of Chemistry 10.1039/C5SC01699A
Naegeli, A.; Michaud, Gaëlle; Schubert, M.; Lin, C.-W.; Lizak, C.; Darbre, Tamis; Reymond, Jean-Louis; Aebi, M. (2014). Substrate Specificity of Cytoplasmic N-Glycosyltransferase. Journal of biological chemistry, 289(35), pp. 24521-24532. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M114.579326
Bartoloni, Marco; Waltersperger, Sandro; Bumann, Mario; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2014). Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide. Arkivoc, 2014(3), p. 113. Michigan Publishing 10.3998/ark.5550190.p008.500
Stach, Michaela; Siriwardena, Thissa; Köhler, Thilo; van Delden, Christian; Darbre, Tamis; Reymond, Jean-Louis (2014). Combining Topology and Sequence Design for the Discovery of Potent Antimicrobial Peptide Dendrimers against Multidrug-Resistant Pseudomonas aeruginosa. Angewandte Chemie (International ed.), 53(47), pp. 12827-12831. Wiley-VCH 10.1002/anie.201409270
Lizak, C.; Gerber, Sabine; Zinne, D.; Michaud, Gaëlle; Schubert, M.; Chen, F.; Bucherer, Monika; Darbre, Tamis; Zenobi, R.; Reymond, Jean-Louis; Locher, K. P. (2014). A Catalytically Essential Motif in External Loop 5 of the Bacterial Oligosaccharyltransferase PglB. Journal of biological chemistry, 289(2), pp. 735-746. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M113.524751
Eggimann, Gabriela A.; Blattes, Emilyne; Buschor, Stefanie; Biswas, Rasomoy; Kammer, Stephan M.; Darbre, Tamis; Reymond, Jean-Louis (2014). Designed cell penetrating peptide dendrimers efficiently internalize cargo into cells. Chemical communications, 50(55), pp. 7254-7257. Royal Society of Chemistry 10.1039/C4CC02780A
Filipe, Luis C. S.; Machuqueiro, Miguel; Baptista, Antonio M.; Darbre, Tamis (2013). Unraveling the Conformational Determinants of Peptide Dendrimers Using Molecular Dynamics Simulations. Macromolecules, 46(23), pp. 9427-9436. American Chemical Society 10.1021/ma401574b
Bernardi, Anna; Jiménez-Barbero, Jesus; Casnati, Alessandro; De Castro, Cristina; Darbre, Tamis; Fieschi, Franck; Finne, Jukka; Funken, Horst; Jaeger, Karl-Erich; Lahmann, Martina; Lindhorst, Thisbe K.; Marradi, Marco; Messner, Paul; Molinaro, Antonio; Murphy, Paul V.; Nativi, Cristina; Oscarson, Stefan; Penadés, Soledad; Peri, Francesco; Pieters, Roland J.; ... (2013). Multivalent glycoconjugates as anti-pathogenic agents. Chemical Society reviews, 42(11), pp. 4709-4727. Royal Society of Chemistry 10.1039/C2CS35408J
Geotti-Bianchini, Piero; Darbre, Tamis; Reymond, Jean-Louis (2013). pH-tuned metal coordination and peroxidase activity of a peptide dendrimer enzyme model with a Fe(ii)bipyridine at its core. Organic & biomolecular chemistry, 11(2), pp. 344-352. Royal Society of Chemistry 10.1039/c2ob26551f
Kadam, Rameshwar U.; Bergman, Manfred Max; Garg, Divita; Gabrieli, Gabriele; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2013). Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA. Chemistry - a European journal, 19(50), pp. 17054-17063. Wiley-VCH 10.1002/chem.201302587
Kadam, Rameshwar U.; Garg, Divita; Schwartz, Julian; Visini, Ricardo; Sattler, Michael; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2013). CH−π “T-Shape” Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA. ACS Chemical Biology, 8(9), pp. 1925-1930. American Chemical Society 10.1021/cb400303w
Ravi, Harish Kumar; Stach, Michaela; Soares, Thereza; Darbre, Tamis; Reymond, Jean-Louis; Cascella, Michele (2013). Electrostatics and Flexibility Drive Membrane Recognition and Early Penetration by Antimicrobial Peptide Dendrimer bH1. Chemical communications, 49(78), pp. 8821-8823. Royal Society of Chemistry 10.1039/C3CC44912B
Reymond, Jean-Louis; Bergman, Manfred Max; Darbre, Tamis (2013). Glycopeptide dendrimers as Pseudomonas aeruginosa biofilm inhibitors. Chemical Society reviews, 42(11), pp. 4814-4822. Royal Society of Chemistry 10.1039/c3cs35504g
Gerber, S.; Lizak, C.; Michaud, Gaëlle; Bucher, M.; Darbre, Tamis; Aebi, M.; Reymond, Jean-Louis; Locher, K. P. (2013). Mechanism of bacterial oligosaccharyltransferase: in vitro quantification of sequon binding and catalysis. Journal of biological chemistry, 288(13), pp. 8849-8861. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.445940
Kwok, Albert; Eggimann, Gabriela; Reymond, Jean-Louis; Darbre, Tamis; Hollfelder, Florian (2013). Peptide Dendrimer/Lipid Hybrid Systems Are Efficient DNA Transfection Reagents: Structure–Activity Relationships Highlight the Role of Charge Distribution Across Dendrimer Generations. ACS nano, 7(5), pp. 4668-4682. American Chemical Society 10.1021/nn400343z
Eggimann, Gabriela; Buschor, Stefanie; Darbre, Tamis; Reymond, Jean-Louis (2013). Convergent synthesis and cellular uptake of multivalent cell penetrating peptides derived from Tat, Antp, pVEC, TP10 and SAP. Organic & biomolecular chemistry, 11(39), pp. 6717-6733. Royal Society of Chemistry 10.1039/c3ob41023d
Lizak, Christian; Gerber, Sabina; Michaud, Gaëlle; Schubert, Mario; Fan, Yao-Yun; Bucher, Monika; Darbre, Tamis; Aebi, Markus; Reymond, Jean-Louis; Locher, Kaspar P. (2013). Unexpected reactivity and mechanism of carboxamide activation in bacterial N-linked protein glycosylation. Nature communications, 4(2627), p. 2627. Nature Publishing Group 10.1038/ncomms3627
Reymond, Jean-Louis; Darbre, Tamis (2013). Expanding the Topological Space of Bioactive Peptides. CHIMIA, 67(12), pp. 864-867. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2013.864
Darbre, Tamis; Reymond, Jean-Louis (2012). Dendritic glycopeptides as Pseudomonas aeruginosa biofilm inhibitors. Journal of Peptide Science, 18, S55-S56. Chichester: John Wiley & Sons
Eggimann, G.; Buschor, S.; Darbre, Tamis; Reymond, Jean-Louis (2012). Branched and Dendritic Cell Penetrating Peptides. Journal of Peptide Science, 18, S152-S152. Chichester: John Wiley & Sons
Reymond, Jean-Louis; Darbre, Tamis (2012). Peptide and glycopeptide dendrimer apple trees as enzyme models and for biomedical applications. Organic & biomolecular chemistry, 10(8), pp. 1483-1492. Cambridge: Royal Society of Chemistry 10.1039/c2ob06938e
Stach, Michaela; Maillard, Noélie; Kadam, Rameshwar; Kalbermatter, David; Meury, M.; Page, Malcolm; Fotiadis, Dimitrios José; Darbre, Tamis; Reymond, Jean-Louis (2012). Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini. Medicinal chemistry communications - MedChemComm, 3(1), pp. 86-89. Cambridge: Royal Society of Chemistry 10.1039/c1md00272d
Bartoloni, Marco; Kadam, Rameshwar U.; Schwartz, Julian; Furrer, Julien; Darbre, Tamis; Reymond, Jean-Louis (2011). Expanding the accessible chemical space by solid phase synthesis of bicyclic homodetic peptides. Chemical communications, 47(47), p. 12634. Cambridge: Royal Society of Chemistry 10.1039/c1cc15704c
Kadam, Rameshwar U.; Bergman, Manfred Max; Hurley, Matthew; Garg, Divita; Cacciarini, Martina; Swiderska, Magdalena A.; Nativi, Cristina; Sattler, Michael; Smyth, Alan R.; Williams, Paul; Camara, Miguel; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2011). A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin LecA and of Pseudomonas aeruginosa Biofilms. Angewandte Chemie (International ed.), 50(45), pp. 10631-10635. Weinheim: Wiley-VCH 10.1002/anie.201104342
Johansson, Emma M.V.; Kadam, Rameshwar U.; Rispoli, Gabriele; Crusz, Shanika A.; Bartels, Kai-Malte; Diggle, Stephen P.; Camara, Miguel; Williams, Paul; Jaeger, Karl-Erich; Darbre, Tamis; Reymond, Jean-Louis (2011). Inhibition of Pseudomonas aeruginosa biofilms with a glycopeptide dendrimer containing D-amino acids. Medicinal chemistry communications - MedChemComm, 2(5), pp. 418-420. Cambridge: Royal Society of Chemistry 10.1039/c0md00270d
Maillard, N.; Biswas, Rasomoy; Darbre, Tamis; Reymond, Jean-Louis (2011). Combinatorial Discovery of Peptide Dendrimer Enzyme Models Hydrolyzing Isobutyryl Fluorescein. ACS combinatorial science, 13(3), pp. 310-320. Washington, D.C.: American Chemical Society 10.1021/co200006z
Uhlich, N.A.; Darbre, Tamis; Reymond, Jean-Louis (2011). Peptide dendrimer enzyme models for ester hydrolysis and aldolizationprepared by convergent thioether ligation. Organic & biomolecular chemistry, 9(20), pp. 7071-7084. Cambridge: Royal Society of Chemistry 10.1039/c1ob05877k
Johansson, Emma M.V.; Dubois, Joëlle; Darbre, Tamis; Reymond, Jean-Louis (2010). Glycopeptide dendrimer colchicine conjugates targeting cancer cells. Bioorganic & medicinal chemistry, 18(17), pp. 6589-6597. Amsterdam: Elsevier 10.1016/j.bmc.2010.04.026
Uhlich, Nicolas A.; Natalello, Antonino; Kadam, Rameshwar U.; Doglia, Silvia M.; Reymond, Jean-Louis; Darbre, Tamis (2010). Structure and Binding of Peptide-Dendrimer Ligands to Vitamin B12. ChemBioChem, 11(3), pp. 358-365. Weinheim: Wiley-VCH 10.1002/cbic.200900657
Uhlich, Nicolas A.; Sommer, Peter; Bühr, Claudia; Schürch, Stefan; Reymond, Jean-Louis; Darbre, Tamis (2009). Remote Control of Bipyridine-Metal Coordination within a Peptide Dendrimer. Chemical communications(41), p. 6237. Cambridge: Royal Society of Chemistry 10.1039/b912291e
Sommer, Peter; Fluxa, Viviana S.; Darbre, Tamis; Reymond, Jean-Louis (2009). Proteolysis of Peptide Dendrimers. ChemBioChem, 10(9), pp. 1527-1536. Weinheim: Wiley-VCH 10.1002/cbic.200900060
Maillard, Noélie; Darbre, Tamis; Reymond, Jean-Louis (2009). Identification of Catalytic Peptide Dendrimers by "Off-Bead" in Silica High-Throughput Screening of Combinatorial Libraries. Journal of combinatorial chemistry, 11(4), pp. 667-675. Washington, D.C.: American Chemical Society 10.1021/cc9000289
Kolomiets, Elena; Swiderska, Magdalena A.; Kadam, Rameshwar U.; Johansson, Emma M.V.; Jaeger, Karl-Erich; Darbre, Tamis; Reymond, Jean-Louis (2009). Glycopeptide dendrimers with high affinity for the fucose binding lectin PA-IIL from Pseudomonas aeruginosa. ChemMedChem, 4(4), pp. 562-569. Weinheim: Wiley-VCH 10.1002/cmdc.200800380
Maillard, Noélie; Clouet, Anthony; Darbre, Tamis; Reymond, Jean-Louis (2009). Combinatorial Libraries of Peptide Dendrimers: Design, Synthesis, On-Bead High-Throughput Screening, Bead Decoding and Characterization. Nature protocols, 4(2), pp. 132-142. London: Nature Publishing Group 10.1038/nprot.2008.241
Johansson, Emma M.V.; Crusz, Shanika A.; Kolomiets, Elena; Buts, Lieven; Kadam, Rameshwar U.; Cacciarini, Martina; Bartels, Kai-Malte; Diggle, Stephen P.; Cámara, Miguel; Williams, Paul; Loris, Remy; Nativi, Cristina; Rosenau, Frank; Jaeger, Karl-Erich; Darbre, Tamis; Reymond, Jean-Louis (2008). Inhibition and Dispersion of Pseudomonas aeruginosa Biofilms by Glycopeptide Dendrimers Targeting the Fucose-Specific Lectin LecB. Chemistry & biology, 15(12), pp. 1249-1257. San Francisco, Calif.: Current Biology Ltd. 10.1016/j.chembiol.2008.10.009
Duléry, Vincent; Uhlich, Nicolas A.; Maillard, Noélie; Fluxa, Viviana S.; Garcia, Julian; Dumy, Pascal; Renaudet, Olivier; Reymond, Jean-Louis; Darbre, Tamis (2008). A cyclodecapeptide ligand to vitamin B12. Organic & biomolecular chemistry, 6(22), pp. 4134-4141. Cambridge: Royal Society of Chemistry 10.1039/b811234g
Darbre, Tamis; Reymond, Jean-Louis (2008). Glycopeptide dendrimers for biomedical applications. Current topics in medicinal chemistry, 8(14), pp. 1286-1293. Hilversum: Bentham Science Publishers 10.2174/156802608785849058
Sommer, Peter; Uhlich, Nicolas; Reymond, Jean-Louis; Darbre, Tamis (2008). A Peptide Dendrimer Model for Vitamin B(12). ChemBioChem, 9(5), pp. 689-693. Weinheim: Wiley-VCH 10.1002/cbic.200700606
Wedemeyer-Exl, Christina; Darbre, Tamis; Keese, Reinhart (2008). Preparation of Dicyano- and Methylcobinamide from Vitamin B12a. Synthesis - journal of synthetic organic chemistry, 2008(21), pp. 3429-3432. Stuttgart: Thieme 10.1055/s-0028-1083187
Wedemeyer-Exl, Christina; Darbre, Tamis; Keese, Reinhart (2007). Model studies for the thiol-mediated methyl transfer to corrinoids. Organic & biomolecular chemistry, 5(13), pp. 2119-2128. Cambridge: Royal Society of Chemistry 10.1039/b703421k
Javor, Sacha; Delort, Estelle; Darbre, Tamis; Reymond, Jean-Louis (2007). A Peptide Dendrimer Enzyme Model with a Single Catalytic Site at the Core. Journal of the American Chemical Society, 129(43), pp. 13238-13246. Washington, D.C.: American Chemical Society 10.1021/ja074115f
Johansson, Emma; Kolomiets, Elena; Rosenau, Frank; Jaeger, Karl-Erich; Darbre, Tamis; Reymond, Jean-Louis (2007). Combinatorial Variation of Branching Length and Multivalency in a Large (390,625 Member) Glycopeptide Dendrimer Library: Ligands for Fucose-specific Lectins. New journal of chemistry, 31(7), pp. 1291-1299. London: Royal Society of Chemistry 10.1039/b616051b
Kolomiets, Elena; Johansson, Emma; Renaudet, Olivier; Darbre, Tamis; Reymond, Jean-Louis (2007). Neoglycopeptide Dendrimer Libraries as a Source of Lectin Binding Ligands. Organic letters, 9(8), pp. 1465-1468. Washington, D.C.: American Chemical Society 10.1021/ol070119d
Darbre, Tamis; Reymond, Jean-Louis (2007). A Peptide Dendrimer Approach to Artificial Enzymes. Chimica oggi / Chemistry today, 25, pp. 25-27. Milano: TeknoScienze
Darbre, Tamis; Reymond, Jean-Louis (2006). Peptide Dendrimers as Artificial Enzymes, Receptors, and Drug-Delivery Agents. Accounts of chemical research, 39(12), pp. 925-934. Easton, Pa.: American Chemical Society 10.1021/ar050203y
Kofoed, Jacob; Darbre, Tamis; Reymond, Jean-Louis (2006). Artificial aldolases from peptide dendrimer combinatorial libraries. Organic & biomolecular chemistry, 4(17), pp. 3268-3281. Cambridge: Royal Society of Chemistry 10.1039/b607342e
Delort, Estelle; Nguyen-Trung, Nhat-Quang; Darbre, Tamis; Reymond, Jean-Louis (2006). Synthesis and Activity of Histidine Containing Catalytic Peptide Dendrimers. Journal of organic chemistry, 71(12), pp. 4468-4480. Washington, D.C.: American Chemical Society 10.1021/jo060273y
Kofoed, Jacob; Darbre, Tamis; Reymond, Jean-Louis (2006). Dual Mechanism of Zinc-Proline Catalyzed Aldol Reactions in Water. Chemical communications, 14(14), p. 1482. Cambridge: Royal Society of Chemistry 10.1039/b600703a
Clouet, Anthony; Darbre, Tamis; Reymond, Jean-Louis (2006). Combinatorial Synthesis, Selection and Properties of Esterase Peptide Dendrimers. Biopolymers, 84(1), pp. 114-123. Hoboken, N.J.: John Wiley & Sons, Inc. 10.1002/bip.20394
Reymond, Jean-Louis; Darbre, Tamis (2011). Combinatorial Libraries of Dendritic Glycoclusters. In: Renaudet, O.; Spinelli, N. (eds.) Synthesis and Biological Applications of Glycoconjugates (pp. 116-128). Bentham Science Publishers
Zamolo, Susanna Joelle; Reymond, Jean-Louis; Darbre, Tamis (22 June 2019). Peptide based vectors for CRISPR-Cas9 delivery (Unpublished). In: 26th American Peptide Symposium. Monterey, CA. 22-27 June 2019.
Darbre, Tamis (20 August 2017). Glycopeptide dendrimers as Pseudomonas aeruginosa biofilm inhibitors (Unpublished). In: American Chemical Society, ACS meeting. Washington DC, USA. Aug 20-24 2017.
Darbre, Tamis (20 August 2017). Potent Antimicrobial Peptide Dendrimers against Multi-Drug Resistant P. aeruginosa and A. baumannii (Unpublished). In: American Chemical Society, ACS meeting. Washington DC, USA. Aug 20-24 2017.
Darbre, Tamis (6 January 2017). Peptide dendrimers: enzyme models and interactions with cell membranes (Unpublished). In: Kick off meeting MMBio EU Research Training network. Cambridge, UK. Jan 6-8, 2017.
Darbre, Tamis (2017). Peptide Dendrimer-Lipid Conjugates are efficient Transfection reagents of DNA and siRNA (Unpublished). In: 13th German Peptide Symposium. Erlangen. Germany. March 20-March 23.
Darbre, Tamis (10 November 2016). Novel antimicrobial peptide dendrimers against multi-resistant bacteria (Unpublished). In: 7th CABMM (center for applied biotechnology and molecular medicine) Symposium. University of Zürich, Irchel Canmpus. 10.11.2016.
Darbre, Tamis (4 September 2016). Antimicrobial peptide dendrimers against multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii with enhanced angiogenic effect (Unpublished). In: European Peptide Sympsoium (EPS). Leipzig, Germany. 04.-09.09.2016.
Darbre, Tamis (6 June 2016). Potent Antimicrobial Peptide Dendrimers against Multi-Drug Resistant P. aeruginosa and A. baumanii (Unpublished). In: Antimicrobial Peptide Symposium (AMP). Montpellier, France. 06.-08.06.2016.
Darbre, Tamis (24 April 2016). Synthesis and structure determination of bridged bicyclic peptides: potential scaffolds for radical enzyme models (Unpublished). In: Clickgene and CM1201 meeting (COST action). Grenoble, France. 24.-27.04.2016.
Darbre, Tamis (June 2015). Potent Antimicrobial Peptide Dendrimers against Multi-Drug Resistant Pseudomonas aeruginosa (Unpublished). In: American Peptide Symposium. Orlando, FL, USA. 20.-25.06.2015.
Darbre, Tamis (June 2015). Potent Antimicrobial Peptide Dendrimers against Multi-Drug Resistant Pseudomonas aeruginosa (Unpublished). In: Challenges in Chemical Biology (ISACS16). Zürich, Schweiz. 15.-18.06.2015.
Darbre, Tamis (March 2015). Combined Topology and Sequence Design Uncovers Potent Antimicrobial Peptide Dendrimers against Multi-Drug Resistant Pseudomonas aeruginosa (Unpublished). In: German Peptide Symposium Darmstadt. Darmstadt, Deutschland. 21.03.2015.
Michaud, Gaëlle; Bergman, Manfred Max; Salerno, Gianluca; Gillon, Emilie; Imberty, Anne; Richichi, Barbara; Nativi, Cristina; Darbre, Tamis; Reymond, Jean-Louis (June 2014). Synthesis of glycopeptide dendrimers targeting LecA, LecB, or both (Unpublished). In: COST MultiGlycoNano Meeting. Siena, Italy. 25.-28.06.2014.
Bartoloni, M.; Darbre, Tamis; Reymond, Jean-Louis (2012). Synthesis and structure determination of bicyclic bridged peptides. Journal of Peptide Science, 18(S1), S170-S170. John Wiley & Sons
Blattes, E.; Bartoloni, M.; Darbre, Tamis; Reymond, Jean-Louis (2012). Biological applications of bicyclic peptides. Journal of Peptide Science, 18(Supplement), S93-S93. John Wiley & Sons 10.1002/psc.2449
Stach, M.; Darbre, Tamis; Reymond, Jean-Louis (2012). Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini. Journal of Peptide Science, 18, S63-S64. John Wiley & Sons
