Lehtimäki, Terho

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Number of items: 21.

Journal Article

Young, William J; Lahrouchi, Najim; Isaacs, Aaron; Duong, ThuyVy; Foco, Luisa; Ahmed, Farah; Brody, Jennifer A; Salman, Reem; Noordam, Raymond; Benjamins, Jan-Walter; Haessler, Jeffrey; Lyytikäinen, Leo-Pekka; Repetto, Linda; Concas, Maria Pina; van den Berg, Marten E; Weiss, Stefan; Baldassari, Antoine R; Bartz, Traci M; Cook, James P; Evans, Daniel S; ... (2022). Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature communications, 13(1), p. 5144. Nature Publishing Group 10.1038/s41467-022-32821-z

Wang, Zhe; Emmerich, Andrew; Pillon, Nicolas J; Moore, Tim; Hemerich, Daiane; Cornelis, Marilyn C; Mazzaferro, Eugenia; Broos, Siacia; Ahluwalia, Tarunveer S; Bartz, Traci M; Bentley, Amy R; Bielak, Lawrence F; Chong, Mike; Chu, Audrey Y; Berry, Diane; Dorajoo, Rajkumar; Dueker, Nicole D; Kasbohm, Elisa; Feenstra, Bjarke; Feitosa, Mary F; ... (2022). Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. Nature genetics, 54(9), pp. 1332-1344. Nature America 10.1038/s41588-022-01165-1

Pitkänen, Niina; Finkenstedt, Armin; Lamina, Claudia; Juonala, Markus; Kähönen, Mika; Mäkelä, Kari-Matti; Dieplinger, Benjamin; Viveiros, Andre; Melmer, Andreas; Leitner, Isabella; Kedenko, Ludmilla; Seppälä, Ilkka; Viikari, Jorma S A; Mueller, Thomas; Kronenberg, Florian; Paulweber, Bernhard; Lehtimäki, Terho; Zoller, Heinz; Raitakari, Olli T and Dieplinger, Hans (2022). Afamin predicts the prevalence and incidence of nonalcoholic fatty liver disease. Clinical chemistry and laboratory medicine, 60(2), pp. 243-251. Walter de Gruyter 10.1515/cclm-2021-0837

Carmeli, Cristian; Kutalik, Zoltán; Pashupati P., Mishra; Porcu, Eleonora; Delpierre, Cyrille; Delaneau, Olivier; Kelly-Irving, Michelle; Bochud, Murielle; Dhayat, Nasser A.; Ponte, Belen; Pruijm, Menno; Ehret, Georg; Kähönen, Mika; Lehtimäki, Terho; Raitakari, Olli T.; Vineis, Paolo; Kivimäki, Mika; Chadeau-Hyam, Marc; Dermitzakis, Emmanouil; Vuilleumier, Nicolas; ... (2021). Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two cohort studies. Scientific reports, 11(1), p. 3100. Springer Nature 10.1038/s41598-021-82714-2

Ochoa-Rosales, Carolina; Portilla-Fernandez, Eliana; Nano, Jana; Wilson, Rory; Lehne, Benjamin; Mishra, Pashupati P; Gao, Xu; Ghanbari, Mohsen; Rueda-Ochoa, Oscar L; Juvinao-Quintero, Diana; Loh, Marie; Zhang, Weihua; Kooner, Jaspal S; Grabe, Hans J; Felix, Stephan B; Schöttker, Ben; Zhang, Yan; Gieger, Christian; Müller-Nurasyid, Martina; Heier, Margit; ... (2020). Epigenetic Link Between Statin Therapy and Type 2 Diabetes. Diabetes care, 43(4), pp. 875-884. American Diabetes Association 10.2337/dc19-1828

Teumer, Alexander; Li, Yong; Ghasemi, Sahar; Prins, Bram P; Wuttke, Matthias; Hermle, Tobias; Giri, Ayush; Sieber, Karsten B; Qiu, Chengxiang; Kirsten, Holger; Tin, Adrienne; Chu, Audrey Y; Bansal, Nisha; Feitosa, Mary F; Wang, Lihua; Chai, Jin-Fang; Cocca, Massimiliano; Fuchsberger, Christian; Gorski, Mathias; Hoppmann, Anselm; ... (2019). Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nature communications, 10(1), p. 4130. Nature Publishing Group 10.1038/s41467-019-11576-0

Evangelou, Evangelos; Gao, He; Chu, Congying; Ntritsos, Georgios; Blakeley, Paul; Butts, Andrew R; Pazoki, Raha; Suzuki, Hideaki; Koskeridis, Fotios; Yiorkas, Andrianos M; Karaman, Ibrahim; Elliott, Joshua; Luo, Qiang; Aeschbacher, Stefanie; Bartz, Traci M; Baumeister, Sebastian E; Braund, Peter S; Brown, Michael R; Brody, Jennifer A; Clarke, Toni-Kim; ... (2019). New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature human behaviour, 3(9), pp. 950-961. Springer Nature 10.1038/s41562-019-0653-z

Wuttke, Matthias; Li, Yong; Li, Man; Sieber, Karsten B; Feitosa, Mary F; Gorski, Mathias; Tin, Adrienne; Wang, Lihua; Chu, Audrey Y; Hoppmann, Anselm; Kirsten, Holger; Giri, Ayush; Chai, Jin-Fang; Sveinbjornsson, Gardar; Tayo, Bamidele O; Nutile, Teresa; Fuchsberger, Christian; Marten, Jonathan; Cocca, Massimiliano; Ghasemi, Sahar; ... (2019). A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nature genetics, 51(6), pp. 957-972. Nature America 10.1038/s41588-019-0407-x

Fiorito, Giovanni; McCrory, Cathal; Robinson, Oliver; Carmeli, Cristian; Rosales, Carolina Ochoa; Zhang, Yan; Colicino, Elena; Dugué, Pierre-Antoine; Artaud, Fanny; McKay, Gareth J; Jeong, Ayoung; Mishra, Pashupati P; Nøst, Therese H; Krogh, Vittorio; Panico, Salvatore; Sacerdote, Carlotta; Tumino, Rosario; Palli, Domenico; Matullo, Giuseppe; Guarrera, Simonetta; ... (2019). Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis. Aging, 11(7), pp. 2045-2070. Impact Journals 10.18632/aging.101900

Franceschini, Nora; Giambartolomei, Claudia; de Vries, Paul S; Finan, Chris; Bis, Joshua C; Huntley, Rachael P; Lovering, Ruth C; Tajuddin, Salman M; Winkler, Thomas W; Graff, Misa; Kavousi, Maryam; Dale, Caroline; Smith, Albert V; Hofer, Edith; van Leeuwen, Elisabeth M; Nolte, Ilja M; Lu, Lingyi; Scholz, Markus; Sargurupremraj, Muralidharan; Pitkänen, Niina; ... (2018). GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature communications, 9(1), p. 5141. Nature Publishing Group 10.1038/s41467-018-07340-5

Ligthart, Symen; Vaez, Ahmad; Võsa, Urmo; Stathopoulou, Maria G; de Vries, Paul S; Prins, Bram P; Van der Most, Peter J; Tanaka, Toshiko; Naderi, Elnaz; Rose, Lynda M; Wu, Ying; Karlsson, Robert; Barbalic, Maja; Lin, Honghuang; Pool, René; Zhu, Gu; Macé, Aurélien; Sidore, Carlo; Trompet, Stella; Mangino, Massimo; ... (2018). Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. American journal of human genetics, 103(5), pp. 691-706. Cell Press 10.1016/j.ajhg.2018.09.009

Evangelou, Evangelos; Warren, Helen R; Mosen-Ansorena, David; Mifsud, Borbala; Pazoki, Raha; Gao, He; Ntritsos, Georgios; Dimou, Niki; Cabrera, Claudia P; Karaman, Ibrahim; Ng, Fu Liang; Evangelou, Marina; Witkowska, Katarzyna; Tzanis, Evan; Hellwege, Jacklyn N; Giri, Ayush; Velez Edwards, Digna R; Sun, Yan V; Cho, Kelly; Gaziano, J Michael; ... (2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature genetics, 50(10), pp. 1412-1425. Nature America 10.1038/s41588-018-0205-x

Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K; Walters, Raymond K; Bras, Jose; Duncan, Laramie; Escott-Price, Valentina; Falcone, Guido J; Gormley, Padhraig; Malik, Rainer; Patsopoulos, Nikolaos A; Ripke, Stephan; Wei, Zhi; Yu, Dongmei; Lee, Phil H; Turley, Patrick; Grenier-Boley, Benjamin; Chouraki, Vincent; Kamatani, Yoichiro; Berr, Claudine; ... (2018). Analysis of shared heritability in common disorders of the brain. Science, 360(6395) American Association for the Advancement of Science 10.1126/science.aap8757

Tedja, Milly S; Wojciechowski, Robert; Hysi, Pirro G; Eriksson, Nicholas; Furlotte, Nicholas A; Verhoeven, Virginie J M; Iglesias, Adriana I; Meester-Smoor, Magda A; Tompson, Stuart W; Fan, Qiao; Khawaja, Anthony P; Cheng, Ching-Yu; Höhn, René; Yamashiro, Kenji; Wenocur, Adam; Grazal, Clare; Haller, Toomas; Metspalu, Andres; Wedenoja, Juho; Jonas, Jost B; ... (2018). Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Nature genetics, 50(6), pp. 834-848. Springer Nature 10.1038/s41588-018-0127-7

Fan, Qiao; Verhoeven, Virginie J M; Wojciechowski, Robert; Barathi, Veluchamy A; Hysi, Pirro G; Guggenheim, Jeremy A; Höhn, René; Vitart, Veronique; Khawaja, Anthony P; Yamashiro, Kenji; Hosseini, S Mohsen; Lehtimäki, Terho; Lu, Yi; Haller, Toomas; Xie, Jing; Delcourt, Cécile; Pirastu, Mario; Wedenoja, Juho; Gharahkhani, Puya; Venturini, Cristina; ... (2016). Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nature communications, 7(11008), p. 11008. Nature Publishing Group 10.1038/ncomms11008

Delcourt, Cécile; Korobelnik, Jean-François; Buitendijk, Gabriëlle H S; Foster, Paul J; Hammond, Christopher J; Piermarocchi, Stefano; Peto, Tunde; Jansonius, Nomdo; Mirshahi, Alireza; Hogg, Ruth E; Bretillon, Lionel; Topouzis, Fotis; Deak, Gabor; Grauslund, Jakob; Broe, Rebecca; Souied, Eric H; Creuzot-Garcher, Catherine; Sahel, José; Daien, Vincent; Lehtimäki, Terho; ... (2016). Ophthalmic epidemiology in Europe: the "European Eye Epidemiology" (E3) consortium. European journal of epidemiology, 31(2), pp. 197-210. Springer 10.1007/s10654-015-0098-2

Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H; Johnson, Andrew D; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele; ... (2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature communications, 7, p. 10023. Nature Publishing Group 10.1038/ncomms10023

Silbernagel, Günther; Chapman, M. John; Genser, Bernd; Kleber, Marcus E.; Fauler, Günter; Scharnagl, Hubert; Grammer, Tanja B.; Mäkelä, Kari-Matti; Kähönen, Mika; Carmena, Rafael; Rietzschel, Ernst R.; Bruckert, Eric; Deanfield, John E.; Raitakari, Olli T.; Lehtimäki, Terho; März, Winfried (2014). Reply: Intestinal cholesterol absorption and cardiovascular risk. Journal of the American College of Cardiology, 63(7), pp. 696-697. Elsevier 10.1016/j.jacc.2013.09.081

Seppälä, Ilkka; Kleber, Marcus E.; Lyytikäinen, Leo-Pekka; Hernesniemi, Jussi A.; Mäkelä, Kari-Matti; Oksala, Niku; Laaksonen, Reijo; Pilz, Stefan; Tomaschitz, Andreas; Silbernagel, Günther; Boehm, Bernhard O.; Grammer, Tanja B.; Koskinen, Tuomas; Juonala, Markus; Hutri-Kähönen, Nina; Alfthan, Georg; Viikari, Jorma S. A.; Kähonen, Mika; Raitakari, Olli T.; März, Winfried; ... (2014). Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. European Heart Journal, 35(8), pp. 524-531. Oxford University Press 10.1093/eurheartj/eht447

Silbernagel, Günther; Chapman, M John; Genser, Bernd; Kleber, Marcus E; Fauler, Günter; Scharnagl, Hubert; Grammer, Tanja B; Boehm, Bernhard O; Mäkelä, Kari-Matti; Kähönen, Mika; Carmena, Rafael; Rietzschel, Ernst R; Bruckert, Eric; Deanfield, John E; Miettinen, Tatu A; Raitakari, Olli T; Lehtimäki, Terho; März, Winfried (2013). High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis. Journal of the American College of Cardiology, 62(4), pp. 291-299. Elsevier 10.1016/j.jacc.2013.01.100

Working Paper

Nagarajan, Pavithra; Winkler, Thomas W; Bentley, Amy R; Miller, Clint L; Kraja, Aldi T; Schwander, Karen; Lee, Songmi; Wang, Wenyi; Brown, Michael R; Morrison, John L; Giri, Ayush; O'Connell, Jeffrey R; Bartz, Traci M; de Las Fuentes, Lisa; Gudmundsdottir, Valborg; Guo, Xiuqing; Harris, Sarah E; Huang, Zhijie; Kals, Mart; Kho, Minjung; ... (8 March 2024). A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations. medRxiv: the preprint server for health sciences. 10.1101/2024.03.07.24303870

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