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Karamitopoulou, Eva; Wenning, Anna Silvia; Acharjee, Animesh; Aeschbacher, Pauline; Marinoni, Ilaria; Zlobec, Inti; Gloor, Beat; Perren, Aurel (2024). Spatial heterogeneity of immune regulators drives dynamic changes of local immune responses, affecting disease outcomes in pancreatic cancer. Clinical cancer research, 30(18), pp. 4215-4226. American Association for Cancer Research 10.1158/1078-0432.CCR-24-0368
Moser, Elisa; Ura, Ayako; Vogel, Loreen; Steiger, Katja; Mogler, Carolin; Evert, Matthias; Märkl, Bruno; Scheidhauer, Klemens; Martignoni, Marc; Friess, Helmut; von Werder, Alexander; Marinoni, Ilaria; Perren, Aurel; Klöppel, Günter; Kasajima, Atsuko (2024). ARX, PDX1, ISL1 and CDX2 expression distinguishes five subgroups of PanNETs with correlations to histology, hormone expression and outcome. (In Press). Modern pathology, 37(11), p. 100595. Elsevier 10.1016/j.modpat.2024.100595
Chouchane, Aziz; Kirchner, Philipp; Marinoni, Ilaria; Sticová, Eva; Jirásek, Tomáš; Perren, Aurel (2024). Pancreatic Neuroendocrine Microtumors (WHO 2022) Are Not Always Low-Grade Neoplasms: A Case with a Highly Increased Proliferation Rate. Endocrine pathology, 35(2), pp. 147-153. Springer 10.1007/s12022-024-09802-7
April-Monn, Simon L; Kirchner, Philipp; Detjen, Katharina; Bräutigam, Konstantin; Trippel, Mafalda A; Grob, Tobias; Statzer, Cyril; Maire, Renaud S; Kollár, Attila; Chouchane, Aziz; Kunze, Catarina A; Horst, David; Sadowski, Martin C; Schrader, Jörg; Marinoni, Ilaria; Wiedenmann, Bertram; Perren, Aurel (2024). Patient derived tumoroids of high grade neuroendocrine neoplasms for more personalized therapies. NPJ precision oncology, 8(59) Springer Nature 10.1038/s41698-024-00549-2
Gulde, Sebastian; Foscarini, Alessia; April-Monn, Simon L; Genio, Edoardo; Marangelo, Alessandro; Satam, Swapna; Helbling, Daniel; Falconi, Massimo; Toledo, Rodrigo A; Schrader, Jörg; Perren, Aurel; Marinoni, Ilaria; Pellegata, Natalia S (2022). Combined Targeting of Pathogenetic Mechanisms in Pancreatic Neuroendocrine Tumors Elicits Synergistic Antitumor Effects. Cancers, 14(22) MDPI AG 10.3390/cancers14225481
Depoilly, Thomas; Leroux, Raffaele; Andrade, Dafne; Nicolle, Remy; Dioguardi Burgio, Marco; Marinoni, Ilaria; Dokmak, Safi; Ruszniewski, Philippe; Hentic, Olivia; Paradis, Valérie; De Mestier, Louis; Perren, Aurel; Couvelard, Anne; Cros, Jérôme (2022). Immunophenotypic and molecular characterization of pancreatic neuroendocrine tumors producing serotonin. Modern pathology, 35(11), pp. 1713-1722. Springer Nature 10.1038/s41379-022-01110-x
Battistella, Anna; Partelli, Stefano; Andreasi, Valentina; Marinoni, Ilaria; Palumbo, Diego; Tacelli, Matteo; Lena, Marco Schiavo; Muffatti, Francesca; Mushtaq, Junaid; Capurso, Gabriele; Arcidiacono, Paolo Giorgio; De Cobelli, Francesco; Doglioni, Claudio; Perren, Aurel; Falconi, Massimo (2022). Preoperative assessment of microvessel density in nonfunctioning pancreatic neuroendocrine tumors (NF-PanNETs). Surgery, 172(4), pp. 1236-1244. Elsevier 10.1016/j.surg.2022.06.017
Marinoni, Ilaria (2022). Prognostic value of DAXX/ATRX loss of expression and ALT activation in PanNETs: is it time for clinical implementation? Gut, 71(5), pp. 847-848. BMJ Publishing Group 10.1136/gutjnl-2021-324664
Simon, Tincy; Riemer, Pamela; Jarosch, Armin; Detjen, Katharina; Di Domenico, Annunziata; Bormann, Felix; Menne, Andrea; Khouja, Slim; Monjé, Nanna; Childs, Liam H; Lenze, Dido; Leser, Ulf; Rossner, Florian; Morkel, Markus; Blüthgen, Nils; Pavel, Marianne; Horst, David; Capper, David; Marinoni, Ilaria; Perren, Aurel; ... (2022). DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors. Genome medicine, 14(1), p. 24. BioMed Central 10.1186/s13073-022-01018-w
April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014
Saghafinia, Sadegh; Homicsko, Krisztian; Di Domenico, Annunziata; Wullschleger, Stephan; Perren, Aurel; Marinoni, Ilaria; Ciriello, Giovanni; Michael, Iacovos P; Hanahan, Douglas (2021). Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression. Cancer discovery, 11(10), pp. 2638-2657. American Association for Cancer Research 10.1158/2159-8290.CD-20-1637
Rinke, Anja; Auernhammer, Christoph J; Bodei, Lisa; Kidd, Mark; Krug, Sebastian; Lawlor, Rita; Marinoni, Ilaria; Perren, Aurel; Scarpa, Aldo; Sorbye, Halfdan; Pavel, Marianne Ellen; Weber, Matthias M; Modlin, Irvin; Gress, Thomas M (2021). Treatment of advanced gastroenteropancreatic neuroendocrine neoplasia, are we on the way to personalised medicine? Gut, 70(9), pp. 1768-1781. BMJ Publishing Group 10.1136/gutjnl-2020-321300
Bräutigam, Konstantin; Rodríguez-Calero, Antonio; Kim-Fuchs, Corina; Kollár, Attila; Trepp, Roman; Marinoni, Ilaria; Perren, Aurel (2021). Update on Histological Reporting Changes in Neuroendocrine Neoplasms. Current Oncology Reports, 23(6), p. 65. Springer 10.1007/s11912-021-01062-6
April-Monn, Simon Leonhard; Wiedmer, Tabea; Skowronska, Magdalena; Maire, Renaud; Schiavo Lena, Marco; Trippel, Mafalda; Di Domenico, Annunziata; Muffatti, Francesca; Andreasi, Valentina; Capurso, Gabriele; Doglioni, Claudio; Kim-Fuchs, Corina; Gloor, Beat; Zatelli, Maria Chiara; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). 3D Primary Cell Culture: A Novel Preclinical Model For Pancreatic Neuroendocrine Tumors (PanNETs). Neuroendocrinology, 111(3), pp. 273-287. Karger 10.1159/000507669
Di Domenico, Annunziata; Pipinikas, Christodoulos P; Maire, Renaud S; Bräutigam, Konstantin; Simillion, Cedric; Dettmer, Matthias S; Vassella, Erik; Thirlwell, Chrissie; Perren, Aurel; Marinoni, Ilaria (2020). Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression. Communications biology, 3(1), p. 740. Springer Nature 10.1038/s42003-020-01479-y
Boos, Laura A; Schmitt, Anja; Moch, Holger; Komminoth, Paul; Simillion, Cedric; Marinoni, Ilaria; Nikiforov, Yuri E; Nikiforova, Marina N; Perren, Aurel; Dettmer, Matthias S. (2019). MiRNAs Are Involved in Tall Cell Morphology in Papillary Thyroid Carcinoma. Cancers, 11(6) MDPI AG 10.3390/cancers11060885
Michael, Iacovos P; Saghafinia, Sadegh; Tichet, Mélanie; Zangger, Nadine; Marinoni, Ilaria; Perren, Aurel; Hanahan, Douglas (2019). ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis. Developmental cell, 49(3), 409-424.e6. Cell Press 10.1016/j.devcel.2019.04.015
Rindi, Guido; Klersy, Catherine; Albarello, Luca; Baudin, Eric; Bianchi, Antonio; Büchler, Markus W; Caplin, Martyn; Couvelard, Anne; Cros, Jérôme; de Herder, Wouter W; Delle Fave, Gianfranco; Doglioni, Claudio; Federspiel, Birgitte; Fischer, Lars; Fusai, Giuseppe; Gavazzi, Francesca; Hansen, Carsten; Inzani, Frediano; Jann, Henning; Komminoth, Paul; ... (2018). COMPETITIVE TESTING THE WHO 2010 VS THE WHO 2017 GRADING OF PANCREAS NEUROENDOCRINE NEOPLASIA: DATA FROM A LARGE INTERNATIONAL COHORT STUDY. Neuroendocrinology, 107(4), pp. 375-386. Karger 10.1159/000494355
Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136
Di Domenico, Annunziata; Wiedmer, Tabea; Marinoni, Ilaria; Perren, Aurel (2017). Genetic and epigenetic drivers of neuroendocrine tumours (NET). Endocrine-related cancer, 24(9), R315-R334. BioScientifica Ltd. 10.1530/ERC-17-0012
Marinoni, Ilaria; Wiederkehr, Astrid; Wiedmer, Tabea; Pantasis, Sophia; Di Domenico, Annunziata; Rasmus Möller, Frank; Vassella, Erik; Schmitt Kurrer, Anja; Perren, Aurel (2017). Hypo-methylation mediates chromosomal instability in pancreatic NET. Endocrine-related cancer, 24(3), pp. 137-146. BioScientifica Ltd. 10.1530/ERC-16-0554
Falletta, Simona; Partelli, Stefano; Rubini, Corrado; Nann, Dominik; Doria, Andrea; Marinoni, Ilaria; Polenta, Vanessa; Di Pasquale, Carmelina; Degli Uberti, Ettore; Perren, Aurel; Falconi, Massimo; Zatelli, Maria Chiara (2016). mTOR inhibitors response and mTOR pathway in pancreatic neuroendocrine tumors. Endocrine-related cancer, 23(11), pp. 883-891. BioScientifica Ltd. 10.1530/ERC-16-0329
Schmitt Kurrer, Anja; Marinoni, Ilaria; Blank, Annika; Perren, Aurel (2016). New Genetics and Genomic Data on Pancreatic Neuroendocrine Tumors: Implications for Diagnosis, Treatment, and Targeted Therapies. Endocrine pathology, 27(3), pp. 200-204. Springer 10.1007/s12022-016-9447-2
Schmitt Kurrer, Anja; Blank, Annika; Marinoni, Ilaria; Komminoth, Paul; Perren, Aurel (2016). Histopathology of NET: Current concepts and new developments. Best practice & research. Clinical endocrinology & metabolism, 30(1), pp. 33-43. Elsevier 10.1016/j.beem.2016.02.002
Brügger, Fabienne; Dettmer, Matthias; Neuenschwander, Maja; Perren, Aurel; Marinoni, Ilaria; Hewer, Ekkehard (2016). TERT Promoter Mutations but not the Alternative Lengthening of Telomeres Phenotype Are Present in a Subset of Ependymomas and Are Associated With Adult Onset and Progression to Ependymosarcoma. Journal of neuropathology and experimental neurology, 76(1), pp. 61-66. Oxford University Press 10.1093/jnen/nlw106
Blank, Annika; Wehweck, Laura; Marinoni, Ilaria; Boos, Laura Amanda Meret Sophie; Bergmann, Frank; Schmitt Kurrer, Anja; Perren, Aurel (2015). Interlaboratory variability of MIB1 staining in well-differentiated pancreatic neuroendocrine tumors. Virchows Archiv, 467(5), pp. 543-550. Springer 10.1007/s00428-015-1843-3
Marinoni, Ilaria; Schmitt Kurrer, Anja; Vassella, Erik; Dettmer, Matthias; Rudolph, Thomas; Banz, Vanessa Martine; Hunger, Fabio; Pasquinelli, Silvan; Speel, Ernst-Jan; Perren, Aurel (2014). Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors. Gastroenterology, 146(2), 453-460.e5. Elsevier 10.1053/j.gastro.2013.10.020
Marinoni, Ilaria; Lee, Misu; Mountford, Steffeni; Perren, Aurel; Bravi, Ilaria; Jennen, Louise; Feuchtinger, Annette; Drouin, Jacques; Roncaroli, Federico; Pellegata, Natalia S (2012). Characterization of MENX-associated pituitary tumours. Neuropathology & applied neurobiology, 39(3), pp. 256-269. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2990.2012.01278.x
Miederer, Matthias; Molatore, Sara; Marinoni, Ilaria; Perren, Aurel; Spitzweg, Christine; Reder, Sybille; Wester, Hans-Jürgen; Buck, Andreas K; Schwaiger, Markus; Pellegata, Natalia S (2011). Functional Imaging of Pheochromocytoma with Ga-DOTATOC and C-HED in a Genetically Defined Rat Model of Multiple Endocrine Neoplasia. International journal of molecular imaging, 2011, p. 175352. New York, N.Y.: Hindawi 10.1155/2011/175352
