Eggel, Alexander

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2016

Zellweger, F.; Gasser, P.; Brigger, Daniel; Buschor, P.; Vogel, Monique; Eggel, Alexander (2016). A novel bispecific DARPin targeting FcγRIIB and FcεRI-bound IgE inhibits allergic responses (In Press). Allergy Wiley-Blackwell 10.1111/all.13109

2015

Smith, Lucas K; He, Yingbo; Park, Jeong-Soo; Bieri, Gregor; Snethlage, Cedric E; Lin, Karin; Gontier, Geraldine; Wabl, Rafael; Plambeck, Kristopher E; Udeochu, Joe; Wheatley, Elizabeth G; Bouchard, Jill; Eggel, Alexander; Narasimha, Ramya; Grant, Jacqueline L; Luo, Jian; Wyss-Coray, Tony; Villeda, Saul A (2015). β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis. Nature medicine, 21(8), pp. 932-937. Nature Publishing Group 10.1038/nm.3898

2014

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

2013

Hagmann, Björn; Odermatt, Andrea; Eggel, Alexander; Dahinden, Clemens A.; Fux, Michaela (22 August 2013). Interferon-α antagonizes IL-3-mediated immunoregulatory functions of human basophils (Unpublished). In: 15th ICI (International Congress of Immunology). Milan, Italy.

Hagmann, Björn; Odermatt, Andrea; Eggel, Alexander; Dahinden, Clemens A.; Fux, Michaela (3 April 2013). Co-activation of JAK/STAT and p38 MAPK pathways by type I interferon enhances apoptosis in human basophils (Unpublished). In: 25th Meeting of the Swiss Immunology PhD Students. Wolfsberg. 03.-05.04.2013.

2012

Kim, Beomkyu; Eggel, Alexander; Tarchevskaya, Svetlana S; Vogel, Monique; Prinz, Heino; Jardetzky, Theodore S (2012). Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor. Nature, 491(7425), pp. 613-7. London: Macmillan Journals Ltd. 10.1038/nature11546

Kim, Beomkyu; Tarchevskaya, Svetlana S; Eggel, Alexander; Vogel, Monique; Jardetzky, Theodore S (2012). A time-resolved fluorescence resonance energy transfer assay suitable for high-throughput screening for inhibitors of immunoglobulin E-receptor interactions. Analytical biochemistry, 431(2), pp. 84-9. San Diego, Calif.: Elsevier 10.1016/j.ab.2012.09.010

Wurzburg, Beth A; Kim, Beomkyu; Tarchevskaya, Svetlana S; Eggel, Alexander; Vogel, Monique; Jardetzky, Theodore S (2012). An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation. Journal of biological chemistry, 287(43), pp. 36251-7. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.407502

2011

Eggel, A; Buschor, P; Baumann, M J; Amstutz, P; Stadler, B M; Vogel, M (2011). Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein. Allergy, 66(7), pp. 961-8. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02546.x

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