04 Faculty of Medicine > Pre-clinic Human Medicine > Department of Clinical Research (DCR) > DCR Unit Maurice E. Müller Building > Forschungsgruppe Orthopädische Chirurgie

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Anwander, H; Siebenrock, KA; Tannast, M; Steppacher, SD (2017). Labral Reattachment in Femoroacetabular Impingement Surgery Results in Increased 10-year Survivorship Compared With Resection. Clinical orthopaedics and related research, 475(4), pp. 1178-1188. Springer 10.1007/s11999-016-5114-7

Haefeli, PC; Albers, CE; Steppacher, SD; Tannast, M; Büchler, L (2017). What Are the Risk Factors for Revision Surgery After Hip Arthroscopy for Femoroacetabular Impingement at 7-year Followup? Clinical orthopaedics and related research, 475(4), pp. 1169-1177. Springer 10.1007/s11999-016-5115-6


Hoppe, S; Keel, MJ (2016). Pedicle screw augmentation in osteoporotic spine: indications, limitations and technical aspects. European journal of trauma and emergency surgery, 43(1), pp. 3-8. Springer-Medizin-Verlag 10.1007/s00068-016-0750-x

Weihs, J; Scacchi, P; Hess, R; Albers, CE (2016). [Resection at symptomatic cam impingement. Use of a minimally invasive antero-lateral approach]. Orthopäde, 45(4), pp. 349-354. Springer-Medizin-Verlag 10.1007/s00132-015-3180-2

Largiadèr, Felix; Saeger, Hans-Detlev; Keel, Marius; Bruns, Christiane (eds.) (2016). Checkliste Chirurgie [Edited Textbook] . Georg Thieme Verlag 10.1055/b-004-132240

Stok, Kathryn S; Besler, Bryce A; Steiner, Thomas H; Villarreal Escudero, Ana V; Zulliger, Martin A; Wilke, Markus; Atal, Kailash; Quintin, Aurelie; Koller, Bruno; Müller, Ralph; Nesic, Dobrila (2016). Three-Dimensional Quantitative Morphometric Analysis (QMA) for In Situ Joint and Tissue Assessment of Osteoarthritis in a Preclinical Rabbit Disease Model. PLoS ONE, 11(1), e0147564. Public Library of Science 10.1371/journal.pone.0147564

Keel, M (2016). Weichteilschaden: Grundlagen, offene Frakturen, Amputationsverletzungen, Kompartment-syndrom, Biss- und Stichverletzungen, Schussverletzungen, Explosionsverletzungen, Erfrierung, Ingestion ätzender Substanzen. In: Bühren, Volker; Keel, Marius Johann B.; Marzi, Ingo (eds.) Checkliste Traumatologie (pp. 194-348). Stuttgart New York: Georg Thieme Verlag


Hunziker, Ernst Bruno; Lippuner, Kurt; Keel, Marius; Shintani, Nahoko (2015). An educational review of cartilage repair: precepts & practice - myths & misconceptions - progress & prospects. Osteoarthritis and cartilage, 23(3), pp. 334-350. Elsevier 10.1016/j.joca.2014.12.011

Siebenrock, Klaus-Arno (2015). Editorial comment: symposium: 2014 Bernese Hip Symposium. Clinical orthopaedics and related research, 473(4), pp. 1201-1203. Springer 10.1007/s11999-014-4128-2


Choy, John; Albers, Christoph; Siebenrock, Klaus-Arno; Dolder, Silvia; Hofstetter, Wilhelm; Klenke, Frank M. (2014). Incorporation of RANKL promotes osteoclast formation and osteoclast activity on β-TCP ceramics. Bone, 69, pp. 80-88. Elsevier 10.1016/j.bone.2014.09.013

Chan, Samantha; Calandriello, Elena; Wuertz, K.; Keel, Marius; Benneker, Lorin Michael; Gantenbein, Benjamin (May 2014). Co-culture of Notochordal Cells with Nucleus pulposus and Annulus fibrosus cells under normoxia and hypoxia. Global Spine Journal, 4(1_suppl), s-0034-1376563-s-0034-1376563. Thieme 10.1055/s-0034-1376563

Liu, Li; Ecker, Timo; Schumann, Steffen; Siebenrock, Klaus-Arno; Zheng, Guoyan (2014). Preliminary Study on Finite Element Simulation for Optimizing Acetabulum Reorientation after Periacetabular Osteotomy. In: Bello, Fernando; Cotin, Stéphane (eds.) ISBMS 2014, LNCS 8789. Lecture Notes in Computer Science: Vol. 8789 (pp. 155-162). Cham: Springer 10.1007/978-3-319-12057-7_18


Byun, Sangwon; Sinskey, Yunna L; Lu, Yihong C S; Ort, Tatiana; Kavalkovich, Karl; Sivakumar, Pitchumani; Hunziker, Ernst Bruno; Frank, Eliot H; Grodzinsky, Alan J (2013). Transport of anti-IL-6 antigen binding fragments into cartilage and the effects of injury. Archives of biochemistry and biophysics, 532(1), pp. 15-22. Elsevier 10.1016/j.abb.2012.12.020

Albers, Christoph E; Hofstetter, Wilhelm; Siebenrock, Klaus A; Landmann, Regine; Klenke, Frank M. (2013). In vitro cytotoxicity of silver nanoparticles on osteoblasts and osteoclasts at antibacterial concentrations. Nanotoxicology, 7(1), pp. 30-36. London: Informa Healthcare 10.3109/17435390.2011.626538

Montjovent, Marc-Oliver; Siegrist, Mark; Klenke, Frank M; Wetterwald, Antoinette; Dolder, Silvia; Hofstetter, Wilhelm (2013). Expression of antagonists of WNT and BMP signaling after non-rigid fixation of osteotomies. Bone, 53(1), pp. 79-86. New York, N.Y.: Elsevier 10.1016/j.bone.2012.11.027

Hofstetter, Wilhelm; Sehr, Harald; De Wild, Michael; Portenier, Jeannette; Gobrecht, Jens; Hunziker, Ernst Bruno (2013). Modulation of human osteoblasts by metal surface chemistry. Journal of biomedical materials research. Part A, 101(8), pp. 2355-2364. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.34541

Shintani, Nahoko; Siebenrock, Klaus-Arno; Hunziker, Ernst Bruno (2013). TGF-ß1 enhances the BMP-2-induced chondrogenesis of bovine synovial explants and arrests downstream differentiation at an early stage of hypertrophy. PLoS ONE, 8(1), e53086. Public Library of Science 10.1371/journal.pone.0053086


Chan, Samantha; Benneker, Lorin Michael; Siebenrock, Klaus-Arno; Gantenbein-Ritter, Benjamin (2012). A Reproducible Papain-Induced Disk Degeneration Model of Reduced GAG and Hydration. Global Spine Journal, 2(S01), p. 39. Thieme 10.1055/s-0032-1319920


Wu, Gang; Hunziker, Ernst B; Zheng, Yuanna; Wismeijer, Daniel; Liu, Yuelian (2011). Functionalization of deproteinized bovine bone with a coating-incorporated depot of BMP-2 renders the material efficiently osteoinductive and suppresses foreign-body reactivity. Bone, 49(6), pp. 1323-30. New York, N.Y.: Elsevier 10.1016/j.bone.2011.09.046


Wernike, E; Montjovent, MO; Liu, Y; Wismeijer, D; Hunziker, EB; Siebenrock, KA; Hofstetter, W; Klenke, FM (2010). VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo. European cells & materials eCM, 19, pp. 30-40. Aberystwyth (UK): University of Wales

Wu, Gang; Liu, Yuelian; Iizuka, Tateyuki; Hunziker, Ernst B (2010). Biomimetic coating of organic polymers with a protein-functionalized layer of calcium phosphate: the surface properties of the carrier influence neither the coating characteristics nor the incorporation mechanism or release kinetics of the protein. Tissue engineering. Part C - methods, 16(6), pp. 1255-65. New Rochelle, N.Y.: Mary Ann Liebert 10.1089/ten.tec.2009.0588

Wernike, E; Hofstetter, W; Liu, Y; Wu, G; Sebald, HJ; Wismeijer, D; Hunziker, EB; Siebenrock, KA; Klenke, FM (2010). Long-term cell-mediated protein release from calcium phosphate ceramics. Journal of biomedical materials research, 92(2), pp. 463-74. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.32411

Hägi, Tobias T; Enggist, Lukas; Michel, Daniel; Ferguson, Stephen J; Liu, Yuelian; Hunziker, Ernst B (2010). Mechanical insertion properties of calcium-phosphate implant coatings. Clinical oral implants research, 21(11), pp. 1214-1222. Oxford: Wiley-Blackwell 10.1111/j.1600-0501.2010.01916.x

Schumann, Steffen; Puls, Marc; Ecker, Timo; Schwaegli, Tobias; Stifter, Jan; Siebenrock, Klaus-Arno; Zheng, Guoyan (2010). Determination of Pelvic Orientation from Ultrasound Images Using Patch-SSMs and a Hierarchical Speed of Sound Compensation Strategy. In: Navab, Nassir; Jannin, Pierre (eds.) Information Processing in Computer-Assisted Interventions: IPCAI 2010. Lecture Notes in Computer Science: Vol. 6135 (pp. 157-167). Berlin Heidelberg: Springer 10.1007/978-3-642-13711-2_15

Hägi, TT; Wu, G; Liu, Y; Hunziker, EB (2010). Cell-mediated BMP-2 liberation promotes bone formation in a mechanically unstable implant environment. Bone, 46(5), pp. 1322-1327. New York, N.Y.: Elsevier 10.1016/j.bone.2010.02.010


Liu, Yuelian; Hunziker, Ernst Bruno (2009). Biomimetic Coatings and Their Biological Functionalization. In: León, Betty; Jansen, John (eds.) Thin Calcium Phosphate Coatings for Medical Implants (pp. 301-314). New York: Springer Verlag 10.1007/978-0-387-77718-4_11

Liu, Y; de Groot, K; Hunziker, EB (2009). Biomimetic mineral coatings in dental and orthopaedic implantology. Frontiers of materials science in China, 2009(3 (2)), pp. 154-162. Beijing: SP Higher Education Press


Hunziker, E B; Kapfinger, E; Geiss, J (2007). The structural architecture of adult mammalian articular cartilage evolves by a synchronized process of tissue resorption and neoformation during postnatal development. Osteoarthritis and cartilage, 15(4), 403 - 413. Amsterdam: Elsevier 10.1016/j.joca.2006.09.010

Liu, Yuelian; Enggist, Lukas; Küffer, Alexander Friedrich; Buser, Daniel; Hunziker, Ernst Bruno (2007). The influence of BMP-2 and its mode of delivery on the osteoconductivity of implant surfaces during the early phase of osseointegration. Biomaterials, 28(16), pp. 2677-2686. Oxford: Elsevier 10.1016/j.biomaterials.2007.02.003

Liu, Yuelian; Huse, Robert O; de Groot, Klaas; Buser, Daniel; Hunziker, Ernst Bruno (2007). Delivery mode and efficacy of BMP-2 in association with implants. Journal of dental research, 86(1), pp. 84-89. Thousand Oaks, Calif.: Sage 10.1177/154405910708600114

Nicolae, Claudia; Ko, Ya-Ping; Miosge, Nicolai; Niehoff, Anja; Studer, Daniel; Enggist, Lukas; Hunziker, Ernst B; Paulsson, Mats; Wagener, Raimund; Aszodi, Attila (2007). Abnormal collagen fibrils in cartilage of matrilin-1/matrilin-3-deficient mice. Journal of biological chemistry, 282(30), pp. 22163-75. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M610994200

Hunziker, Ernst B (2007). Cartilage histomorphometry. Methods in molecular medicine, 135, pp. 147-166. Totowa, N.J.: Humana Press

Shintani, Nahoko; Hunziker, Ernst B (2007). Chondrogenic differentiation of bovine synovium: bone morphogenetic proteins 2 and 7 and transforming growth factor beta1 induce the formation of different types of cartilaginous tissue. Arthritis & rheumatism, 56(6), pp. 1869-79. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.22701

Kurth, T; Hedbom, E; Shintani, N; Sugimoto, M; Chen, F H; Haspl, M; Martinovic, S; Hunziker, E B (2007). Chondrogenic potential of human synovial mesenchymal stem cells in alginate. Osteoarthritis and cartilage, 15(10), pp. 1178-89. Amsterdam: Elsevier 10.1016/j.joca.2007.03.015

Shintani, Nahoko; Kurth, Tobias; Hunziker, Ernst B (2007). Expression of cartilage-related genes in bovine synovial tissue. Journal of orthopaedic research, 25(6), pp. 813-9. Hoboken, N.J.: Wiley 10.1002/jor.20345

Patra, Debabrata; Xing, Xiaoyun; Davies, Sherri; Bryan, Jennifer; Franz, Carl; Hunziker, Ernst B; Sandell, Linda J (2007). Site-1 protease is essential for endochondral bone formation in mice. Journal of cell biology, 179(4), pp. 687-700. New York, N.Y.: Rockefeller Institute Press 10.1083/jcb.200708092

Tsang, Kwok Yeung; Chan, Danny; Cheslett, Deborah; Chan, Wilson C W; So, Chi Leong; Melhado, Ian G; Chan, Tori W Y; Kwan, Kin Ming; Hunziker, Ernst B; Yamada, Yoshihiko; Bateman, John F; Cheung, Kenneth M C; Cheah, Kathryn S E (2007). Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function. PLoS biology, 5(3), e44. Lawrence, Kans.: Public Library of Science 10.1371/journal.pbio.0050044


Hunziker, E; Spector, M; Libera, J; Gertzman, A; Woo, SL; Ratcliffe, A; Lysaght, M; Coury, A; Kaplan, D; Vunjak-Novakovic, G (2006). Translation from research to applications. Tissue engineering, 12(12), pp. 3341-64. Larchmont, N.Y.: Mary Ann Liebert 10.1089/ten.2006.12.3341

Liu, Y; Huse, R O; de Groot, K; Buser, D; Hunziker, E B (2006). Quantitative evaluation/comparison of the osteoconductivity of BMP-2 by 4 different delivery modes in a rat extopic model. Bioceramics


Moretti, M; Wendt, D; Schaefer, D; Jakob, M; Hunziker, E B; Heberer, M; Martin, I (2005). Structural characterization and reliable biomechanical assessment of integrative cartilage repair. Journal of biomechanics, 38(9), pp. 1846-54. New York, N.Y.: Elsevier 10.1016/j.jbiomech.2004.08.021

Quinn, Thomas M; Hunziker, Ernst B; Häuselmann, Hans-Jörg (2005). Variation of cell and matrix morphologies in articular cartilage among locations in the adult human knee. Osteoarthritis and cartilage, 13(8), pp. 672-8. Amsterdam: Elsevier 10.1016/j.joca.2005.04.011

Park, Y; Sugimoto, M; Watrin, A; Chiquet, M; Hunziker, E B (2005). BMP-2 induces the expression of chondrocyte-specific genes in bovine synovium-derived progenitor cells cultured in three-dimensional alginate hydrogel. Osteoarthritis and cartilage, 13(6), pp. 527-36. Amsterdam: Elsevier 10.1016/j.joca.2005.02.006

Liu, Y; de Groot, K; Hunziker, E B (2005). BMP-2 liberated from biomimetic implant coatings induces and sustains direct ossification in an ectopic rat model. Bone, 36(5), pp. 745-57. New York, N.Y.: Elsevier 10.1016/j.bone.2005.02.005

Liu, Y M; de Groot, K; Hunziker, E B (2005). Cell-mediated protein release from calcium-phosphate-coated titanium implants. Journal of controlled release, 101(1-3), pp. 346-7. Amsterdam: Elsevier

Bengtsson, Therese; Aszodi, Attila; Nicolae, Claudia; Hunziker, Ernst B; Lundgren-Akerlund, Evy; Fässler, Reinhard (2005). Loss of alpha10beta1 integrin expression leads to moderate dysfunction of growth plate chondrocytes. Journal of cell science, 118(Pt 5), pp. 929-36. Cambridge: Company of Biologists Limited 10.1242/jcs.01678

Docheva, Denitsa; Hunziker, Ernst B; Fässler, Reinhard; Brandau, Oliver (2005). Tenomodulin is necessary for tenocyte proliferation and tendon maturation. Molecular and cellular biology, 25(2), pp. 699-705. Washington, D.C.: American Society for Microbiology 10.1128/MCB.25.2.699-705.2005


Szafranski, Jon D; Grodzinsky, Alan J; Burger, Elke; Gaschen, Veronique; Hung, Han-Hwa; Hunziker, Ernst B (2004). Chondrocyte mechanotransduction: effects of compression on deformation of intracellular organelles and relevance to cellular biosynthesis. Osteoarthritis and cartilage, 12(12), pp. 937-46. Amsterdam: Elsevier 10.1016/j.joca.2004.08.004

Park, Yongdoo; Lutolf, Matthias P; Hubbell, Jeffrey A; Hunziker, Ernst B; Wong, Marcy (2004). Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue engineering, 10(3-4), pp. 515-22. Larchmont, N.Y.: Mary Ann Liebert 10.1089/107632704323061870

Mikic, B; Clark, R T; Battaglia, T C; Gaschen, V; Hunziker, E B (2004). Altered hypertrophic chondrocyte kinetics in GDF-5 deficient murine tibial growth plates. Journal of orthopaedic research, 22(3), pp. 552-6. Hoboken, N.J.: Wiley 10.1016/j.orthres.2003.09.002

Liu, Y; de Groot, K; Hunziker, E B (2004). Osteoinductive implants: the mise-en-scène for drug-bearing biomimetic coatings. Annals of biomedical engineering, 32(3), pp. 398-406. Cambridge: Springer 10.1023/B:ABME.0000017536.10767.0f

Liu, Yuelian; Hunziker, Ernst B; Layrolle, Pierre; De Bruijn, Joost D; De Groot, Klaas (2004). Bone morphogenetic protein 2 incorporated into biomimetic coatings retains its biological activity. Tissue engineering, 10(1-2), pp. 101-8. Larchmont, N.Y.: Mary Ann Liebert 10.1089/107632704322791745

Patwari, P; Gaschen, V; James, I E; Berger, E; Blake, S M; Lark, M W; Grodzinsky, A J; Hunziker, E B (2004). Ultrastructural quantification of cell death after injurious compression of bovine calf articular cartilage. Osteoarthritis and cartilage, 12(3), pp. 245-52. Amsterdam: Elsevier 10.1016/j.joca.2003.11.004

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