In vitro-ex vivo model systems for nanosafety assessment

Wick, P.; Chortarea, S.; Guenat, Olivier Thierry; Roesslein, M.; Stucki, Janick; Hirn, S.; Petri-Fink, A.; Rothen-Rutishauser, B. (2015). In vitro-ex vivo model systems for nanosafety assessment. European Journal of Nanomedicine, 7(3), pp. 169-179. De Gruyter 10.1515/ejnm-2014-0049

Preview

Text ejnm-2014-0049.pdf - Published Version Available under License Publisher holds Copyright. Download (2MB) | Preview

Engineered nanomaterials have unique and novel properties enabling wide-ranging new applications in nearly all fields of research. As these new properties have raised concerns about potential adverse effects for the environment and human health, extensive efforts are underway to define reliable, cost- and time-effective, as well as mechanistic-based testing strategies to replace the current method of animal testing, which is still the most prevalent model used for the risk assessment of chemicals. Current approaches for nanomaterials follow this line. The aim of this review is to explore and qualify the relevance of new in vitro and ex vivo models in (nano)material safety assessment, a crucial prerequisite for translation into applications.

Interest & Impact

Downloads

404 since deposited on 10 Jun 2015
27 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item