Bonadies, Nicolas

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2023

Andina, Nicola; de Meuron, Louise; Schnegg-Kaufmann, Annatina Sarah; Sarangdhar, Mayuresh Anant; Ansermet, Camille; Bombaci, Giuseppe; Batta, Kiran; Keller, Nino; Porret, Naomi A; Angelillo, Anne; Bonadies, Nicolas; Allam, Ramanjaneyulu (2023). Increased Inflammasome Activation Is Associated with Aging and Chronic Myelomonocytic Leukemia Disease Severity. Journal of immunology, 210(5), pp. 580-589. American Association of Immunologists 10.4049/jimmunol.2200412

2022

Brunner, Andrew M; Leitch, Heather A; van de Loosdrecht, Arjan A; Bonadies, Nicolas (2022). Management of patients with lower-risk myelodysplastic syndromes. Blood cancer journal, 12(166), p. 166. Nature Publishing Group 10.1038/s41408-022-00765-8

Chanias, Ioannis; Bonadies, Nicolas (2022). Diagnostic Approach, Clinical Implications and Management of Clonal Cytopenia of Undetermined Significance. Healthbook TIMES oncology hematology, 14(4), pp. 24-33. The Healthbook Company 10.36000/hbT.OH.2022.14.091

Rüfer, Axel; Angermann, Hubert; Benz, Rudolf; Bonadies, Nicolas; Calderoni, Antonello; Cantoni, Nathan; Efthymiou, Anna; Escher, Robert; Favre, Geneviève; Friess, Dorothea; Gschwend, Andreas; Himmelmann, Andreas; Holbro, Andreas; Keller, Peter; Kouroupi, Eirini; Lehmann, Thomas; Pedarnig, Nikolaus; Rigamonti, Véronique; Samii, Kaveh; Schmidt, Adrian; ... (2022). Real-world Data From the Swiss Lenalidomide in MDS del(5q) (SLIM)-Registry Identify New Chances and Challenges in Lenalidomide Treatment of Patients With MDS del(5q). HemaSphere, 6(7), e741. Wolters Kluwer Health 10.1097/HS9.0000000000000741

Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry; Yu, Eric Chi-Wang; Mackie, Gillian M; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M and Allam, Ramanjaneyulu (2022). LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202101226

Uldry, Anne-Christine; Maciel-Dominguez, Anabel; Jornod, Maïwenn; Buchs, Natasha; Braga-Lagache, Sophie; Brodard, Justine; Jankovic, Jovana; Bonadies, Nicolas; Heller, Manfred (2022). Effect of Sample Transportation on the Proteome of Human Circulating Blood Extracellular Vesicles. International journal of molecular sciences, 23(9), p. 4515. MDPI 10.3390/ijms23094515

Andina, Nicola; de Meuron, Louise; Schnegg-Kaufmann, Annatina Sarah; Ansermet, Camille; Bombaci, Giuseppe; Keller, Nino; Porret, Naomi; Angelillo-Scherrer, Anne; Bonadies, Nicolas; Allam, Ramanjaneyulu (31 January 2022). Heightened NLRP3 inflammasome activation is associated with aging and CMML diseases severity (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2022.01.27.477992

Andina, Nicola; Bonadies, Nicolas; Allam, Ramanjaneyulu (2022). Inflammasome Activation in Myeloid Malignancies-Friend or Foe? Frontiers in cell and developmental biology, 9, p. 825611. Frontiers 10.3389/fcell.2021.825611

Lötscher, Fabian; Seitz, Luca; Simeunovic, Helena; Sarbu, Adela-Cristina; Porret, Naomi; Feldmeyer, Laurence; Borradori, Luca; Bonadies, Nicolas; Maurer, Britta (2022). Case Report: Genetic Double Strike: VEXAS and TET2-Positive Myelodysplastic Syndrome in a Patient With Long-Standing Refractory Autoinflammatory Disease. Frontiers in immunology, 12, p. 800149. Frontiers Research Foundation 10.3389/fimmu.2021.800149

Bonadies, Nicolas (2022). [Prognosis and Therapy of Myelodysplastic Syndrome]. Therapeutische Umschau, 78(2), pp. 93-105. Hogrefe 10.1024/0040-5930/a001334

2021

Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry Bernard Maurice; Chi-Wang Yu, Eric; Mackie, Gillian M.; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C.; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M. and Allam, Ramanjaneyulu (26 August 2021). LRR protein RNH1 dampens the inflammasome activation and is associated with adverse clinical outcomes in COVID-19 patients (In Press) (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.04.12.438219

Hallal, Mahmoud; Braga-Lagache, Sophie; Jankovic, Jovana; Simillion, Cedric; Bruggmann, Rémy; Uldry, Anne-Christine; Allam, Ramanjaneyulu; Heller, Manfred; Bonadies, Nicolas (2021). Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA). BMC cancer, 21(1), p. 789. BioMed Central 10.1186/s12885-021-08479-z

Chanias, Ioannis; Stojkov, Kristina; Stehle, Gregor Th.; Daskalakis, Michael; Simeunovic, Helena; Njue, Linet Muthoni; Schnegg-Kaufmann, Annatina S.; Porret, Naomi A.; Allam, Ramanjaneyulu; Tata, Nageswara Rao; Benz, Rudolf; Ruefer, Axel; Schmidt, Adrian; Adler, Marcel; Rovo, Alicia; Balabanov, Stefan; Stuessi, Georg; Bacher, Ulrike; Bonadies, Nicolas (2021). Myelodysplastic Syndromes in the Postgenomic Era and Future Perspectives for Precision Medicine. Cancers, 13(13) MDPI AG 10.3390/cancers13133296

Bonadies, Nicolas; Rovó, Alicia; Porret, Naomi; Bacher, Ulrike (2021). When Should We Think of Myelodysplasia or Bone Marrow Failure in a Thrombocytopenic Patient? A Practical Approach to Diagnosis. Journal of clinical medicine, 10(5) MDPI 10.3390/jcm10051026

Kasprzak, A; Nachtkamp, K; Kondakci, M; Schroeder, T; Kobbe, G; Kündgen, A; Kaivers, J; Rautenberg, C; Haas, R; Gattermann, N; Bonadies, Nicolas; Germing, U (2021). Analysis of the impact of adherence to guidelines and expert advice in patients with myelodysplastic syndromes. Annals of hematology, 100(2), pp. 455-463. Springer-Verlag 10.1007/s00277-020-04325-7

Pleyer, Lisa; Leisch, Michael; Kourakli, Alexandra; Padron, Eric; Maciejewski, Jaroslaw Pawel; Xicoy Cirici, Blanca; Kaivers, Jennifer; Ungerstedt, Johanna; Heibl, Sonja; Patiou, Peristera; Hunter, Anthony Michael; Mora, Elvira; Geissler, Klaus; Dimou, Maria; Jimenez Lorenzo, Maria-José; Melchardt, Thomas; Egle, Alexander; Viniou, Athina-Nora; Patel, Bhumika Jayantibhai; Arnan, Montserrat; ... (2021). Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study. The Lancet. Haematology, 8(2), e135-e148. Elsevier 10.1016/S2352-3026(20)30374-4

Graf, Johannes R.; Forster, Stefan; Bruehl, Frido K.; Banz, Yara; Hallal, Mahmoud; Brodard, Justine; Bacher, Vera Ulrike; Allam, Ramanjaneyulu; Schürch, Christian M.; Bonadies, Nicolas (2021). Diagnostic and Prognostic Implications of Caspase-1 and PD-L1 Co-Expression Patterns in Myelodysplastic Syndromes. Cancers, 13(22), p. 5712. MDPI AG 10.3390/cancers13225712

Daskalakis, Michael; Feller, Anita; Noetzli, Jasmine; Bonadies, Nicolas; Arndt, Volker; Baerlocher, Gabriela Maria (2021). Potential to Improve Therapy of Chronic Myeloid Leukemia (CML), Especially for Patients with Older Age: Incidence, Mortality, and Survival Rates of Patients with CML in Switzerland from 1995 to 2017. Cancers, 13(24) MDPI AG 10.3390/cancers13246269

2020

Chanias, Ioannis; Wilk, C Matthias; Benz, Rudolf; Daskalakis, Michael; Stüssi, Georg; Schmidt, Adrian; Bacher, Ulrike; Bonadies, Nicolas (2020). Survey on Recommended Health Care for Adult Patients with Myelodysplastic Syndromes Identifies Areas for Improvement. International journal of environmental research and public health, 17(24) Molecular Diversity Preservation International MDPI 10.3390/ijerph17249562

Chanias, Ioannis; Bonadies, Nicolas (2020). Current Standard of Care in Patients with Myelodysplastic Syndromes and Future Perspectives. Healthbook. The online medical journal(6), pp. 10-22. 10.36000/hbT.OH.2020.06.026

Cismaru, Anca Liliana; Rudin, Deborah; Ibañez, Luisa; Liakoni, Evangelia; Bonadies, Nicolas; Kreutz, Reinhold; Carvajal, Alfonso; Lucena, Maria Isabel; Martin, Javier; Sancho Ponce, Esther; Molokhia, Mariam; Eriksson, Niclas; EuDAC, Collaborators; Krähenbühl, Stephan; Largiadèr, Carlo R.; Haschke, Manuel Martin; Hallberg, Pär; Wadelius, Mia; Amstutz, Ursula (2020). Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations. Genes, 11(11) MDPI, Molecular Diversity Preservation International 10.3390/genes11111275

Stojkov, Kristina; Silzle, Tobias; Stussi, Georg; Schwappach, David; Bernhard, Juerg; Bowen, David; Čermák, Jaroslav; Dinmohamed, Avinash G; Eeltink, Corien; Eggmann, Sabrina; Fenaux, Pierre; Germing, Ulrich; Haschke, Manuel; Hellstrom-Lindberg, Eva; Heger, Monika; van de Loosdrecht, Arjan A; Passweg, Jakob; Pfeilstöcker, Michael; Platzbecker, Uwe; Malcovati, Luca; ... (2020). Guideline-based indicators for adult patients with myelodysplastic syndromes. Blood advances, 4(16), pp. 4029-4044. American Society of Hematology 10.1182/bloodadvances.2020002314

Cismaru, Anca Liliana; Grimm, Livia; Rudin, Deborah; Ibañez, Luisa; Liakoni, Evangelia; Bonadies, Nicolas; Kreutz, Reinhold; Hallberg, Pär; Wadelius, Mia; Haschke, Manuel; Largiadèr, Carlo R.; Amstutz, Ursula (2020). High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis. Frontiers in genetics, 11(951), p. 951. Frontiers Media SA 10.3389/fgene.2020.00951

2019

Rudin, Deborah; Spoendlin, Julia; Cismaru, Anca L.; Liakoni, Evangelia; Bonadies, Nicolas; Amstutz, Ursula; Meier, Christoph R; Krähenbühl, Stephan; Haschke, Manuel (2019). Metamizole-associated neutropenia: Comparison of patients with neutropenia and metamizole-tolerant patients. European journal of internal medicine, 68, pp. 36-43. Elsevier 10.1016/j.ejim.2019.07.029

Engelbrecht, Laura; Götze, Katharina; Schwamborn, Kristina; Müller-Thomas, Catharina; Alpermann, Tamara; Bonadies, Nicolas; Legros, Myriam; Flach, Johanna; Pabst, Thomas; Banz, Yara; Bacher, Vera (2019). Correlation of cytomorphology and histopathology in the diagnostic process of myeloid malignancies. Hematology & medical oncology OAT 10.15761/HMO.1000190

Bonadies, Nicolas; Bacher, Vera Ulrike (2019). What role can next-generation sequencing play in myelodysplastic syndrome care? Expert review of hematology, 12(6), pp. 379-382. Taylor & Francis 10.1080/17474086.2019.1613151

Affentranger, Lucas; Bohlius, Julia; Hallal, Mahmoud; Bonadies, Nicolas (2019). Efficacy of granulocyte colony stimulating factor in combination with erythropoiesis stimulating agents for treatment of anemia in patients with lower risk myelodysplastic syndromes: A systematic review. Critical reviews in oncology, hematology, 136, pp. 37-47. Elsevier 10.1016/j.critrevonc.2019.01.021

Ouahchi, Ines; Zhang, Luduo; Benitez Brito, Ramon; Benz, Rudolf; Müller, Rouven; Bonadies, Nicolas; Tchinda, Joëlle (2019). Microarray-based comparative genomic hybridisation reveals additional recurrent aberrations in adult patients evaluated for myelodysplastic syndrome with normal karyotype. British journal of haematology, 184(2), pp. 282-287. Wiley-Blackwell 10.1111/bjh.15068

Bonadies, Nicolas (2019). Myelodysplastische Syndrome: nur kleine Fortschritte in Richtung Präzisionsmedizin. Leading Opinions. Hämatologie & Onkologie, 2019(1), pp. 70-72. Universimed

Benzarti, Sonia; Daskalakis, Michael; Feller, Anita; Bacher, Vera Ulrike; Schnegg-Kaufmann, Annatina; Rüfer, Axel; Holbro, Andreas; Schmidt, Adrian; Benz, Rudolf; Solenthaler, Max; Stussi, Georg; Arndt, Volker; Bonadies, Nicolas (2019). Trends of incidence and survival of patients with chronic myelomonocytic leukemia between 1999 and 2014: A comparison between Swiss and American population-based cancer registries. Cancer epidemiology, 59, pp. 51-57. Elsevier 10.1016/j.canep.2019.01.003

2018

Shumilov, Evgenii; Flach, Johanna; Kohlmann, Alexander; Banz Wälti, Yara; Bonadies, Nicolas; Fiedler, Martin; Pabst, Thomas; Bacher, Ulrike (2018). Current status and trends in the diagnostics of AML and MDS. Blood reviews, 32(6), pp. 508-519. Elsevier 10.1016/j.blre.2018.04.008

Kipfer, B; Daikeler, T; Kuchen, Stefan; Hallal, Mahmoud Malek; Andina, Nicola; Allam, Ramanjaneyulu; Bonadies, Nicolas (2018). Increased cardiovascular comorbidities in patients with myelodysplastic syndromes and chronic myelomonocytic leukemia presenting with systemic inflammatory and autoimmune manifestations. Seminars in hematology, 55(4), pp. 242-247. Elsevier 10.1053/j.seminhematol.2018.05.002

Bürki, Susanne; Shumilov, Evgenii; Bonadies, Nicolas; Flach, Johanna; Legros, Myriam; Banz, Yara; Oppliger-Leibundgut, Elisabeth; Fiedler, Martin; Angelillo, Anne; Rovó, Alicia; Bacher, Vera Ulrike (2018). Coincidence of 5q deletion and the JAK2V617F mutation: report of two patients with overlapping myelodysplastic and myeloproliferative features and review of the literature. Leukemia & lymphoma, 59(9), pp. 2233-2237. Informa Healthcare 10.1080/10428194.2017.1416367

Schnegg-Kaufmann, Annatina; Feller, Anita; Baldomero, Helen; Rovó, Alicia; Manz, Markus G; Gregor, Michael; Efthymiou, Anna; Bargetzi, Mario; Hess, Urs; Spertini, Olivier; Chalandon, Yves; Passweg, Jakob R; Stussi, Georg; Arndt, Volker; Bonadies, Nicolas (2018). Improvement of relative survival in elderly patients with acute myeloid leukaemia emerging from population-based cancer registries in Switzerland between 2001 and 2013. Cancer epidemiology, 52, pp. 55-62. Elsevier 10.1016/j.canep.2017.11.008

Silzle, Tobias; Bonadies, Nicolas (2018). WHO-Klassifikation und Einsatz der «Next-Generation»-Sequenzierung. Info Onkologie & Hämatologie, 2018(2), pp. 22-27. Prime Public Media AG

Bonadies, Nicolas (2018). Myelodysplastische Syndrome. Info@Onkologie, 2018(04), pp. 8-14. Aerzteverlag medinfo AG

Bonadies, Nicolas; Bacher, Vera Ulrike (2018). Implementierung einer Präzisionsmedizin bei Patienten mit MDS und unklaren Zytopenien. Leading Opinions. Hämatologie & Onkologie, 2018(1), pp. 18-22. Universimed

2017

Bonadies, Nicolas (2017). MANAGEMENT OF ADULT PATIENTS WITH MYELODYSPLASTIC SYNDROMES. EMJ hepatology(4.0), pp. 104-112. European Medical Group

Bonadies, Nicolas; Feller, Anita; Rovó, Alicia; Ruefer, Axel; Blum, Sabine; Gerber, Bernhard; Stuessi, Georg; Benz, Rudolf; Cantoni, Nathan; Holbro, Andreas; Schmidt, Adrian; Lehmann, Thomas; Wilk, C Matthias; Arndt, Volker (2017). Trends of classification, incidence, mortality, and survival of MDS patients in Switzerland between 2001 and 2012. Cancer epidemiology, 46, pp. 85-92. Elsevier 10.1016/j.canep.2016.12.005

2016

Bonadies, Nicolas; Rüfer, Axel (2016). Diagnostik und Therapie myelodysplastischer Syndrome. Schweizer Zeitschrift für Onkologie(4), pp. 28-36. Rosenfluh Publikationen AG

2015

Bonadies, Nicolas; Göttgens, Berthold; Calero-Nieto, Fernando J (2015). The LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity. PLoS ONE, 10(7), e0131577. Public Library of Science 10.1371/journal.pone.0131577

2010

Bonadies, Nicola; Pabst, Thomas; Mueller, Beatrice U (2010). Heterozygous deletion of the PU.1 locus in human AML. Blood, 115(2), pp. 331-4. Washington, D.C.: American Society of Hematology 10.1182/blood-2009-03-212225

Bonadies, N; Neururer, Ch; Steege, A; Vallabhapurapu, S; Pabst, T; Mueller, B U (2010). PU.1 is regulated by NF-kappaB through a novel binding site in a 17 kb upstream enhancer element. Oncogene, 29(7), pp. 1062-72. Basingstoke, UK: Nature Publishing Group 10.1038/onc.2009.371

2006

Bonadies, Nicolas; Baud, Patricia; Peter, Hans-Jakob; Buergi, Ulrich; Mueller, Beatrice U (2006). A case report of Clarkson's disease: If you don't know it, you'll miss it. European journal of internal medicine, 17(5), pp. 363-5. Roma: Pozzi 10.1016/j.ejim.2005.12.011

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