Bonadies, Nicolas

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2023

Andina, Nicola; de Meuron, Louise; Schnegg-Kaufmann, Annatina Sarah; Sarangdhar, Mayuresh Anant; Ansermet, Camille; Bombaci, Giuseppe; Batta, Kiran; Keller, Nino; Porret, Naomi A; Angelillo, Anne; Bonadies, Nicolas; Allam, Ramanjaneyulu (2023). Increased Inflammasome Activation Is Associated with Aging and Chronic Myelomonocytic Leukemia Disease Severity. Journal of immunology, 210(5), pp. 580-589. American Association of Immunologists 10.4049/jimmunol.2200412

2022

Brunner, Andrew M; Leitch, Heather A; van de Loosdrecht, Arjan A; Bonadies, Nicolas (2022). Management of patients with lower-risk myelodysplastic syndromes. Blood cancer journal, 12(166), p. 166. Nature Publishing Group 10.1038/s41408-022-00765-8

Chanias, Ioannis; Bonadies, Nicolas (2022). Diagnostic Approach, Clinical Implications and Management of Clonal Cytopenia of Undetermined Significance. Healthbook TIMES oncology hematology, 14(4), pp. 24-33. The Healthbook Company 10.36000/hbT.OH.2022.14.091

Rüfer, Axel; Angermann, Hubert; Benz, Rudolf; Bonadies, Nicolas; Calderoni, Antonello; Cantoni, Nathan; Efthymiou, Anna; Escher, Robert; Favre, Geneviève; Friess, Dorothea; Gschwend, Andreas; Himmelmann, Andreas; Holbro, Andreas; Keller, Peter; Kouroupi, Eirini; Lehmann, Thomas; Pedarnig, Nikolaus; Rigamonti, Véronique; Samii, Kaveh; Schmidt, Adrian; ... (2022). Real-world Data From the Swiss Lenalidomide in MDS del(5q) (SLIM)-Registry Identify New Chances and Challenges in Lenalidomide Treatment of Patients With MDS del(5q). HemaSphere, 6(7), e741. Wolters Kluwer Health 10.1097/HS9.0000000000000741

Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry; Yu, Eric Chi-Wang; Mackie, Gillian M; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M and Allam, Ramanjaneyulu (2022). LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202101226

Uldry, Anne-Christine; Maciel-Dominguez, Anabel; Jornod, Maïwenn; Buchs, Natasha; Braga-Lagache, Sophie; Brodard, Justine; Jankovic, Jovana; Bonadies, Nicolas; Heller, Manfred (2022). Effect of Sample Transportation on the Proteome of Human Circulating Blood Extracellular Vesicles. International journal of molecular sciences, 23(9), p. 4515. MDPI 10.3390/ijms23094515

Andina, Nicola; de Meuron, Louise; Schnegg-Kaufmann, Annatina Sarah; Ansermet, Camille; Bombaci, Giuseppe; Keller, Nino; Porret, Naomi; Angelillo-Scherrer, Anne; Bonadies, Nicolas; Allam, Ramanjaneyulu (31 January 2022). Heightened NLRP3 inflammasome activation is associated with aging and CMML diseases severity (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2022.01.27.477992

Andina, Nicola; Bonadies, Nicolas; Allam, Ramanjaneyulu (2022). Inflammasome Activation in Myeloid Malignancies-Friend or Foe? Frontiers in cell and developmental biology, 9, p. 825611. Frontiers 10.3389/fcell.2021.825611

Lötscher, Fabian; Seitz, Luca; Simeunovic, Helena; Sarbu, Adela-Cristina; Porret, Naomi; Feldmeyer, Laurence; Borradori, Luca; Bonadies, Nicolas; Maurer, Britta (2022). Case Report: Genetic Double Strike: VEXAS and TET2-Positive Myelodysplastic Syndrome in a Patient With Long-Standing Refractory Autoinflammatory Disease. Frontiers in immunology, 12, p. 800149. Frontiers Research Foundation 10.3389/fimmu.2021.800149

Bonadies, Nicolas (2022). [Prognosis and Therapy of Myelodysplastic Syndrome]. Therapeutische Umschau, 78(2), pp. 93-105. Hogrefe 10.1024/0040-5930/a001334

2021

Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry Bernard Maurice; Chi-Wang Yu, Eric; Mackie, Gillian M.; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C.; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M. and Allam, Ramanjaneyulu (26 August 2021). LRR protein RNH1 dampens the inflammasome activation and is associated with adverse clinical outcomes in COVID-19 patients (In Press) (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.04.12.438219

Hallal, Mahmoud; Braga-Lagache, Sophie; Jankovic, Jovana; Simillion, Cedric; Bruggmann, Rémy; Uldry, Anne-Christine; Allam, Ramanjaneyulu; Heller, Manfred; Bonadies, Nicolas (2021). Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA). BMC cancer, 21(1), p. 789. BioMed Central 10.1186/s12885-021-08479-z

Chanias, Ioannis; Stojkov, Kristina; Stehle, Gregor Th.; Daskalakis, Michael; Simeunovic, Helena; Njue, Linet Muthoni; Schnegg-Kaufmann, Annatina S.; Porret, Naomi A.; Allam, Ramanjaneyulu; Tata, Nageswara Rao; Benz, Rudolf; Ruefer, Axel; Schmidt, Adrian; Adler, Marcel; Rovo, Alicia; Balabanov, Stefan; Stuessi, Georg; Bacher, Ulrike; Bonadies, Nicolas (2021). Myelodysplastic Syndromes in the Postgenomic Era and Future Perspectives for Precision Medicine. Cancers, 13(13) MDPI AG 10.3390/cancers13133296

Bonadies, Nicolas; Rovó, Alicia; Porret, Naomi; Bacher, Ulrike (2021). When Should We Think of Myelodysplasia or Bone Marrow Failure in a Thrombocytopenic Patient? A Practical Approach to Diagnosis. Journal of clinical medicine, 10(5) MDPI 10.3390/jcm10051026

Kasprzak, A; Nachtkamp, K; Kondakci, M; Schroeder, T; Kobbe, G; Kündgen, A; Kaivers, J; Rautenberg, C; Haas, R; Gattermann, N; Bonadies, Nicolas; Germing, U (2021). Analysis of the impact of adherence to guidelines and expert advice in patients with myelodysplastic syndromes. Annals of hematology, 100(2), pp. 455-463. Springer-Verlag 10.1007/s00277-020-04325-7

Pleyer, Lisa; Leisch, Michael; Kourakli, Alexandra; Padron, Eric; Maciejewski, Jaroslaw Pawel; Xicoy Cirici, Blanca; Kaivers, Jennifer; Ungerstedt, Johanna; Heibl, Sonja; Patiou, Peristera; Hunter, Anthony Michael; Mora, Elvira; Geissler, Klaus; Dimou, Maria; Jimenez Lorenzo, Maria-José; Melchardt, Thomas; Egle, Alexander; Viniou, Athina-Nora; Patel, Bhumika Jayantibhai; Arnan, Montserrat; ... (2021). Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study. The Lancet. Haematology, 8(2), e135-e148. Elsevier 10.1016/S2352-3026(20)30374-4

Graf, Johannes R.; Forster, Stefan; Bruehl, Frido K.; Banz, Yara; Hallal, Mahmoud; Brodard, Justine; Bacher, Vera Ulrike; Allam, Ramanjaneyulu; Schürch, Christian M.; Bonadies, Nicolas (2021). Diagnostic and Prognostic Implications of Caspase-1 and PD-L1 Co-Expression Patterns in Myelodysplastic Syndromes. Cancers, 13(22), p. 5712. MDPI AG 10.3390/cancers13225712

Daskalakis, Michael; Feller, Anita; Noetzli, Jasmine; Bonadies, Nicolas; Arndt, Volker; Baerlocher, Gabriela Maria (2021). Potential to Improve Therapy of Chronic Myeloid Leukemia (CML), Especially for Patients with Older Age: Incidence, Mortality, and Survival Rates of Patients with CML in Switzerland from 1995 to 2017. Cancers, 13(24) MDPI AG 10.3390/cancers13246269

2020

Chanias, Ioannis; Wilk, C Matthias; Benz, Rudolf; Daskalakis, Michael; Stüssi, Georg; Schmidt, Adrian; Bacher, Ulrike; Bonadies, Nicolas (2020). Survey on Recommended Health Care for Adult Patients with Myelodysplastic Syndromes Identifies Areas for Improvement. International journal of environmental research and public health, 17(24) MDPI 10.3390/ijerph17249562

Chanias, Ioannis; Bonadies, Nicolas (2020). Current Standard of Care in Patients with Myelodysplastic Syndromes and Future Perspectives. Healthbook. The online medical journal(6), pp. 10-22. 10.36000/hbT.OH.2020.06.026

Cismaru, Anca Liliana; Rudin, Deborah; Ibañez, Luisa; Liakoni, Evangelia; Bonadies, Nicolas; Kreutz, Reinhold; Carvajal, Alfonso; Lucena, Maria Isabel; Martin, Javier; Sancho Ponce, Esther; Molokhia, Mariam; Eriksson, Niclas; EuDAC, Collaborators; Krähenbühl, Stephan; Largiadèr, Carlo R.; Haschke, Manuel Martin; Hallberg, Pär; Wadelius, Mia; Amstutz, Ursula (2020). Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations. Genes, 11(11) MDPI 10.3390/genes11111275

Stojkov, Kristina; Silzle, Tobias; Stussi, Georg; Schwappach, David; Bernhard, Juerg; Bowen, David; Čermák, Jaroslav; Dinmohamed, Avinash G; Eeltink, Corien; Eggmann, Sabrina; Fenaux, Pierre; Germing, Ulrich; Haschke, Manuel; Hellstrom-Lindberg, Eva; Heger, Monika; van de Loosdrecht, Arjan A; Passweg, Jakob; Pfeilstöcker, Michael; Platzbecker, Uwe; Malcovati, Luca; ... (2020). Guideline-based indicators for adult patients with myelodysplastic syndromes. Blood advances, 4(16), pp. 4029-4044. American Society of Hematology 10.1182/bloodadvances.2020002314

Cismaru, Anca Liliana; Grimm, Livia; Rudin, Deborah; Ibañez, Luisa; Liakoni, Evangelia; Bonadies, Nicolas; Kreutz, Reinhold; Hallberg, Pär; Wadelius, Mia; Haschke, Manuel; Largiadèr, Carlo R.; Amstutz, Ursula (2020). High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis. Frontiers in genetics, 11(951), p. 951. Frontiers Media SA 10.3389/fgene.2020.00951

2019

Rudin, Deborah; Spoendlin, Julia; Cismaru, Anca L.; Liakoni, Evangelia; Bonadies, Nicolas; Amstutz, Ursula; Meier, Christoph R; Krähenbühl, Stephan; Haschke, Manuel (2019). Metamizole-associated neutropenia: Comparison of patients with neutropenia and metamizole-tolerant patients. European journal of internal medicine, 68, pp. 36-43. Elsevier 10.1016/j.ejim.2019.07.029

Engelbrecht, Laura; Götze, Katharina; Schwamborn, Kristina; Müller-Thomas, Catharina; Alpermann, Tamara; Bonadies, Nicolas; Legros, Myriam; Flach, Johanna; Pabst, Thomas; Banz, Yara; Bacher, Vera (2019). Correlation of cytomorphology and histopathology in the diagnostic process of myeloid malignancies. Hematology & medical oncology OAT 10.15761/HMO.1000190

Bonadies, Nicolas; Bacher, Vera Ulrike (2019). What role can next-generation sequencing play in myelodysplastic syndrome care? Expert review of hematology, 12(6), pp. 379-382. Taylor & Francis 10.1080/17474086.2019.1613151

Affentranger, Lucas; Bohlius, Julia; Hallal, Mahmoud; Bonadies, Nicolas (2019). Efficacy of granulocyte colony stimulating factor in combination with erythropoiesis stimulating agents for treatment of anemia in patients with lower risk myelodysplastic syndromes: A systematic review. Critical reviews in oncology, hematology, 136, pp. 37-47. Elsevier 10.1016/j.critrevonc.2019.01.021

Ouahchi, Ines; Zhang, Luduo; Benitez Brito, Ramon; Benz, Rudolf; Müller, Rouven; Bonadies, Nicolas; Tchinda, Joëlle (2019). Microarray-based comparative genomic hybridisation reveals additional recurrent aberrations in adult patients evaluated for myelodysplastic syndrome with normal karyotype. British journal of haematology, 184(2), pp. 282-287. Wiley-Blackwell 10.1111/bjh.15068

Bonadies, Nicolas (2019). Myelodysplastische Syndrome: nur kleine Fortschritte in Richtung Präzisionsmedizin. Leading Opinions. Hämatologie & Onkologie, 2019(1), pp. 70-72. Universimed

Benzarti, Sonia; Daskalakis, Michael; Feller, Anita; Bacher, Vera Ulrike; Schnegg-Kaufmann, Annatina; Rüfer, Axel; Holbro, Andreas; Schmidt, Adrian; Benz, Rudolf; Solenthaler, Max; Stussi, Georg; Arndt, Volker; Bonadies, Nicolas (2019). Trends of incidence and survival of patients with chronic myelomonocytic leukemia between 1999 and 2014: A comparison between Swiss and American population-based cancer registries. Cancer epidemiology, 59, pp. 51-57. Elsevier 10.1016/j.canep.2019.01.003

2018

Shumilov, Evgenii; Flach, Johanna; Kohlmann, Alexander; Banz Wälti, Yara; Bonadies, Nicolas; Fiedler, Martin; Pabst, Thomas; Bacher, Ulrike (2018). Current status and trends in the diagnostics of AML and MDS. Blood reviews, 32(6), pp. 508-519. Elsevier 10.1016/j.blre.2018.04.008

Kipfer, B; Daikeler, T; Kuchen, Stefan; Hallal, Mahmoud Malek; Andina, Nicola; Allam, Ramanjaneyulu; Bonadies, Nicolas (2018). Increased cardiovascular comorbidities in patients with myelodysplastic syndromes and chronic myelomonocytic leukemia presenting with systemic inflammatory and autoimmune manifestations. Seminars in hematology, 55(4), pp. 242-247. Elsevier 10.1053/j.seminhematol.2018.05.002

Bürki, Susanne; Shumilov, Evgenii; Bonadies, Nicolas; Flach, Johanna; Legros, Myriam; Banz, Yara; Oppliger-Leibundgut, Elisabeth; Fiedler, Martin; Angelillo, Anne; Rovó, Alicia; Bacher, Vera Ulrike (2018). Coincidence of 5q deletion and the JAK2V617F mutation: report of two patients with overlapping myelodysplastic and myeloproliferative features and review of the literature. Leukemia & lymphoma, 59(9), pp. 2233-2237. Informa Healthcare 10.1080/10428194.2017.1416367

Schnegg-Kaufmann, Annatina; Feller, Anita; Baldomero, Helen; Rovó, Alicia; Manz, Markus G; Gregor, Michael; Efthymiou, Anna; Bargetzi, Mario; Hess, Urs; Spertini, Olivier; Chalandon, Yves; Passweg, Jakob R; Stussi, Georg; Arndt, Volker; Bonadies, Nicolas (2018). Improvement of relative survival in elderly patients with acute myeloid leukaemia emerging from population-based cancer registries in Switzerland between 2001 and 2013. Cancer epidemiology, 52, pp. 55-62. Elsevier 10.1016/j.canep.2017.11.008

Silzle, Tobias; Bonadies, Nicolas (2018). WHO-Klassifikation und Einsatz der «Next-Generation»-Sequenzierung. Info Onkologie & Hämatologie, 2018(2), pp. 22-27. Prime Public Media AG

Bonadies, Nicolas (2018). Myelodysplastische Syndrome. Info@Onkologie, 2018(04), pp. 8-14. Aerzteverlag medinfo AG

Bonadies, Nicolas; Bacher, Vera Ulrike (2018). Implementierung einer Präzisionsmedizin bei Patienten mit MDS und unklaren Zytopenien. Leading Opinions. Hämatologie & Onkologie, 2018(1), pp. 18-22. Universimed

2017

Bonadies, Nicolas (2017). MANAGEMENT OF ADULT PATIENTS WITH MYELODYSPLASTIC SYNDROMES. EMJ hepatology(4.0), pp. 104-112. European Medical Group

Bonadies, Nicolas; Feller, Anita; Rovó, Alicia; Ruefer, Axel; Blum, Sabine; Gerber, Bernhard; Stuessi, Georg; Benz, Rudolf; Cantoni, Nathan; Holbro, Andreas; Schmidt, Adrian; Lehmann, Thomas; Wilk, C Matthias; Arndt, Volker (2017). Trends of classification, incidence, mortality, and survival of MDS patients in Switzerland between 2001 and 2012. Cancer epidemiology, 46, pp. 85-92. Elsevier 10.1016/j.canep.2016.12.005

2016

Bonadies, Nicolas; Rüfer, Axel (2016). Diagnostik und Therapie myelodysplastischer Syndrome. Schweizer Zeitschrift für Onkologie(4), pp. 28-36. Rosenfluh Publikationen AG

2015

Bonadies, Nicolas; Göttgens, Berthold; Calero-Nieto, Fernando J (2015). The LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity. PLoS ONE, 10(7), e0131577. Public Library of Science 10.1371/journal.pone.0131577

2010

Bonadies, Nicola; Pabst, Thomas; Mueller, Beatrice U (2010). Heterozygous deletion of the PU.1 locus in human AML. Blood, 115(2), pp. 331-4. Washington, D.C.: American Society of Hematology 10.1182/blood-2009-03-212225

Bonadies, N; Neururer, Ch; Steege, A; Vallabhapurapu, S; Pabst, T; Mueller, B U (2010). PU.1 is regulated by NF-kappaB through a novel binding site in a 17 kb upstream enhancer element. Oncogene, 29(7), pp. 1062-72. Basingstoke, UK: Nature Publishing Group 10.1038/onc.2009.371

2006

Bonadies, Nicolas; Baud, Patricia; Peter, Hans-Jakob; Buergi, Ulrich; Mueller, Beatrice U (2006). A case report of Clarkson's disease: If you don't know it, you'll miss it. European journal of internal medicine, 17(5), pp. 363-5. Roma: Pozzi 10.1016/j.ejim.2005.12.011

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