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Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Yang, Haitang; Ma, Wenyan; Sun, Beibei; Fan, Liwen; Xu, Ke; Hall, Sean; Al-Hurani, Mohammad; Schmid, Ralph A.; Peng, Ren-Wang; Hida, Toyoaki; Wang, Zhexin; Yao, Feng (2021). Smoking signature is superior to programmed death-ligand 1 expression in predicting pathological response to neoadjuvant immunotherapy in lung cancer patients. Translational lung cancer research, 10(9), pp. 3807-3822. AME Publishing 10.21037/tlcr-21-734
Yang, Haitang; Sun, Beibei; Xu, Ke; He, Yunfei; Zhang, Tuo; Hall, Sean; Tan, Swee T; Schmid, Ralph A.; Peng, Ren-Wang; Hu, Guohong; Yao, Feng (2021). Pharmaco-transcriptomic correlation analysis reveals novel responsive signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer. EBioMedicine, 69(103457), p. 103457. Elsevier 10.1016/j.ebiom.2021.103457
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Yang, Haitang; Hall, Sean; Sun, Beibei; Zhao, Liang; Gao, Yanyun; Schmid, Ralph A.; Tan, Swee T; Peng, Ren-Wang; Yao, Feng (2021). NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma. Cancers, 13(7) 10.3390/cancers13071561
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Verstegen, Monique M A; Mezzanotte, Laura; Ridwan, R Yanto; Wang, Kairong; de Haan, Jubi; Schurink, Ivo J; Sierra Parraga, Jésus M; Hoogduijn, Martin; Kessler, Benedikt M; Huang, Honglei; Hall, Sean R. R.; IJzermans, Jan N M; Löwik, Clemens W G M; van der Laan, Luc J W; de Jonge, Jeroen (2019). First Report on Ex vivo Delivery of Paracrine Active Human Mesenchymal Stromal Cells to Liver Grafts During Machine Perfusion. Transplantation, 104(1), e5-e7. Lippincott Williams & Wilkins 10.1097/TP.0000000000002986
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111
Blom, Rebecca Agaatha Maria; Amacker, Mario; Moser, Christian; van Dijk, R Maarten; Bonetti, Raffaela; Seydoux, Emilie; Hall, Sean; von Garnier, Christophe; Blank, Fabian (2017). Virosome-bound antigen enhances DC-dependent specific CD4(+) T cell stimulation, inducing a Th1 and Treg profile in vitro. Nanomedicine : nanotechnology, biology, and medicine, 13(5), pp. 1725-1737. Elsevier 10.1016/j.nano.2017.02.004
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Tsoyi, Konstantin; Hall, Sean; Dalli, Jesmond; Colas, Romain A; Ghanta, Sailaja; Ith, Bonna; Coronata, Anna; Fredenburgh, Laura E; Baron, Rebecca M; Choi, Augustine M K; Serhan, Charles N; Liu, Xiaoli; Perrella, Mark A (2016). Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators. Critical care medicine, 44(12), e1236-e1245. Lippincott Williams & Wilkins 10.1097/CCM.0000000000001999
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Keil, Andreas; Hall, Sean; Körner, Meike; Herrmann, Martin; Schmid, Ralph; Frese, Steffen R. (2016). Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan. Arthritis research & therapy, 18(243), p. 243. BioMed Central 10.1186/s13075-016-1144-5
Blom, Rebecca Agaatha Maria; Erni, Silvia T; Krempaská, Kristína; Schaerer, Olivier; van Dijk, R Maarten; Amacker, Mario; Moser, Christian; Hall, Sean; Von Garnier, Christophe; Blank, Fabian (2016). A Triple Co-Culture Model of the Human Respiratory Tract to Study Immune-Modulatory Effects of Liposomes and Virosomes. PLoS ONE, 11(9), e0163539. Public Library of Science 10.1371/journal.pone.0163539
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
de Mare-Bredemeijer, Emmy L D; Mancham, Shanta; Verstegen, Monique M A; de Ruiter, Petra E; van Gent, Rogier; O'Neill, David; Tilanus, Hugo W; Metselaar, Herold J; de Jonge, Jeroen; Kwekkeboom, Jaap; Hall, Sean; van der Laan, Luc J W (2015). Human graft-derived mesenchymal stromal cells potently suppress alloreactive T-cell responses. Stem cells and development, 24(12), pp. 1436-1447. Mary Ann Liebert 10.1089/scd.2014.0485
Bichsel, Colette Andrea; Hall, Sean; Schmid, Ralph; Guenat, Olivier Thierry; Geiser, Thomas (2015). Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. Tissue engineering. Part A, 21(15-16), p. 2166. Mary Ann Liebert 10.1089/ten.TEA.2014.0545
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Ruppen, Janine; Wildhaber, Franziska Daniela; Strub, Christoph; Hall, Sean; Geiser, Thomas; Schmid, Ralph; Guenat, Olivier Thierry (2015). Towards personalized medicine: Chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform. Lab on a chip, 15(14), pp. 3076-3085. Royal Society of Chemistry 10.1039/C5LC00454C
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Liu, Xiaoli; Hall, Sean; Wang, Zhihong; Huang, He; Ghanta, Sailaja; Di Sante, Moises; Leri, Annarosa; Anversa, Piero; Perrella, Mark A (2015). Rescue of neonatal cardiac dysfunction in mice by administration of cardiac progenitor cells in utero. Nature communications, 6, p. 8825. Nature Publishing Group 10.1038/ncomms9825
Fouraschen, Suomi M G; Hall, Sean; de Jonge, Jeroen; van der Laan, Luc J W (2014). Support of hepatic regeneration by trophic factors from liver-derived mesenchymal stromal/stem cells. Methods in molecular biology, 1213, pp. 89-104. Humana Press 10.1007/978-1-4939-1453-1_9
Hall, Sean R. R.; Jiang, Yajuan; Leary, Elizabeth; Yavanian, Greg; Eminli, Sarah; O'Neill, David W.; Marasco, Wayne A. (2013). Identification and isolation of small CD44-negative mesenchymal stem/progenitor cells from human bone marrow using elutriation and polychromatic flow cytometry. Stem cells translational medicine, 2(8), pp. 567-578. AlphaMed Press 10.5966/sctm.2012-0155
Hall, Sean R. R.; Pedroza-Gonzalez, Alexander; Pan, Qiuwei; Tilanus, Hugo W.; de Jonge, Jeroen; Wagemaker, Gerard; van der Laan, Luc J. W. (2013). Overestimation of hematopoietic stem cell frequencies in human liver grafts. Hepatology, 57(6), pp. 2547-2549. Wiley Interscience 10.1002/hep.26119
Hall, Sean R. R.; Tsoyi, Konstantin; Ith, Bonna; Padera Jr., Robert F.; Lederer, James A.; Wang, Zhihong; Liu, Xiaoli; Perrella, Mark A. (2013). Mesenchymal stromal cells improve survival during sepsis in the absence of heme oxygenase-1: the importance of neutrophils. Stem cells, 31(2), pp. 397-407. AlphaMed Press 10.1002/stem.1270
