![]() | Up a level |
Lin, Ting-Yu; Kleemann, Leon; Jeżowski, Jakub; Dobosz, Dominika; Rawski, Michał; Indyka, Paulina; Ważny, Grzegorz; Mehta, Rahul; Chramiec-Głąbik, Andrzej; Koziej, Łukasz; Ranff, Tristan; Fufezan, Christian; Wawro, Mateusz; Kochan, Jakub; Bereta, Joanna; Leidel, Sebastian A; Glatt, Sebastian (2024). The molecular basis of tRNA selectivity by human pseudouridine synthase 3. Molecular cell, 84(13), 2472-2489.e8. Cell Press 10.1016/j.molcel.2024.06.013
Böttcher, Bettina; Kienast, Sandra D; Leufken, Johannes; Eggers, Cristian; Sharma, Puneet; Leufken, Christine M; Morgner, Bianka; Drexler, Hannes C A; Schulz, Daniela; Allert, Stefanie; Jacobsen, Ilse D; Vylkova, Slavena; Leidel, Sebastian A; Brunke, Sascha (2024). A highly conserved tRNA modification contributes to C. albicans filamentation and virulence. Microbiology spectrum, 12(5), e0425522. American Society for Microbiology 10.1128/spectrum.04255-22
Rauscher, Robert; Eggers, Cristian; Dimitrova-Paternoga, Lyudmila; Shankar, Vaishnavi; Rosina, Alessia; Cristodero, Marina; Paternoga, Helge; Wilson, Daniel N; Leidel, Sebastian A; Polacek, Norbert (2024). Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes. Nucleic acids research, 52(7), pp. 4021-4036. Oxford University Press 10.1093/nar/gkae067
Helm, Mark; Bohnsack, Markus T; Carell, Thomas; Dalpke, Alexander; Entian, Karl-Dieter; Ehrenhofer-Murray, Ann; Ficner, Ralf; Hammann, Christian; Höbartner, Claudia; Jäschke, Andres; Jeltsch, Albert; Kaiser, Stefanie; Klassen, Roland; Leidel, Sebastian A; Marx, Andreas; Mörl, Mario; Meier, Jochen C; Meister, Gunter; Rentmeister, Andrea; Rodnina, Marina; ... (2023). Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications. ACS Chemical Biology, 18(12), pp. 2441-2449. American Chemical Society 10.1021/acschembio.3c00586
Alings, Fiona; Scharmann, Karin; Eggers, Cristian; Böttcher, Bettina; Sokołowski, Mikołaj; Shvetsova, Ekaterina; Sharma, Puneet; Roth, Joël; Rashiti, Leon; Glatt, Sebastian; Brunke, Sascha; Leidel, Sebastian A (2023). Ncs2* mediates in vivo virulence of pathogenic yeast through sulphur modification of cytoplasmic transfer RNA. Nucleic acids research, 51(15), pp. 8133-8149. Oxford University Press 10.1093/nar/gkad564
Meindl, Andreas; Romberger, Markus; Lehmann, Gerhard; Eichner, Norbert; Kleemann, Leon; Wu, Jie; Danner, Johannes; Boesl, Maria; Mesitov, Mikhail; Meister, Gunter; König, Julian; Leidel, Sebastian Andreas; Medenbach, Jan (2023). A rapid protocol for ribosome profiling of low input samples. Nucleic acids research, 51(13), e68. Oxford University Press 10.1093/nar/gkad459
Günl, Franziska; Krischuns, Tim; Schreiber, Julian A; Henschel, Lea; Wahrenburg, Marius; Drexler, Hannes C A; Leidel, Sebastian Andreas; Cojocaru, Vlad; Seebohm, Guiscard; Mellmann, Alexander; Schwemmle, Martin; Ludwig, Stephan; Brunotte, Linda (2023). The ubiquitination landscape of the influenza A virus polymerase. Nature Communications, 14(1), p. 787. Springer Nature 10.1038/s41467-023-36389-0
Leiva, Lorenzo Eugenio; Elgamal, Sara; Leidel, Sebastian A; Orellana, Omar; Ibba, Michael; Katz, Assaf (2022). Oxidative stress strongly restricts the effect of codon choice on the efficiency of protein synthesis in Escherichia coli. Frontiers in Microbiology, 13(1042675), p. 1042675. Frontiers 10.3389/fmicb.2022.1042675
Ravichandran, Keerthiraju E; Kaduhr, Lars; Skupien-Rabian, Bozena; Shvetsova, Ekaterina; Sokołowski, Mikołaj; Krutyhołowa, Ros Cisław; Kwasna, Dominika; Brachmann, Cindy; Lin, Sean; Guzman Perez, Sebastian; Wilk, Piotr; Kösters, Manuel; Grudnik, Przemysław; Jankowska, Urszula; Leidel, Sebastian A; Schaffrath, Raffael; Glatt, Sebastian (2022). E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation. The EMBO journal, 41(20), e111318. EMBO Press 10.15252/embj.2022111318
Sharma, Puneet; Wu, Jie; Nilges, Benedikt S.; Leidel, Sebastian A. (2021). Humans and other commonly used model organisms are resistant to cycloheximide-mediated biases in ribosome profiling experiments. Nature Communications, 12(1), p. 5094. Springer Nature 10.1038/s41467-021-25411-y
Kösters, Manuel; Leufken, Johannes; Leidel, Sebastian A. (2021). SMITER—A Python Library for the Simulation of LC-MS/MS Experiments. Genes, 12(3), p. 396. MDPI 10.3390/genes12030396
Małecki, Jędrzej M; Odonohue, Marie-Francoise; Kim, Ye; Jakobsson, Magnus E; Gessa, Luca; Pinto, Rita; Wu, Jie; Davydova, Erna; Moen, Anders; Olsen, Jesper V; Thiede, Bernd; Gleizes, Pierre-Emmanuel; Leidel, Sebastian A.; Falnes, Pål Ø (2021). Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function. Nucleic acids research, 49(6), pp. 3185-3203. Oxford University Press 10.1093/nar/gkab088
Schulze, Stefan; Igiraneza, Aime Bienfait; Kösters, Manuel; Leufken, Johannes; Leidel, Sebastian A.; Garcia, Benjamin A.; Fufezan, Christian; Pohlschroder, Mechthild (2021). Enhancing Open Modification Searches via a Combined Approach Facilitated by Ursgal. Journal of proteome research, 20(4), pp. 1986-1996. American Chemical Society 10.1021/acs.jproteome.0c00799
Termathe, Martin; Leidel, Sebastian A. (2021). Urm1: A Non-Canonical UBL. Biomolecules, 11(2), p. 139. MDPI 10.3390/biom11020139
Renner, Henrik; Grabos, Martha; Becker, Katharina J; Kagermeier, Theresa E; Wu, Jie; Otto, Mandy; Peischard, Stefan; Zeuschner, Dagmar; TsyTsyura, Yaroslav; Disse, Paul; Klingauf, Jürgen; Leidel, Sebastian A; Seebohm, Guiscard; Schöler, Hans R; Bruder, Jan M (2020). A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids. eLife, 9 eLife Sciences Publications 10.7554/eLife.52904
Fan, Rui; Kim, Yung Su; Wu, Jie; Chen, Rui; Zeuschner, Dagmar; Mildner, Karina; Adachi, Kenjiro; Wu, Guangming; Galatidou, Styliani; Li, Jianhua; Schöler, Hans R.; Leidel, Sebastian A.; Bedzhov, Ivan (2020). Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause. Nature Communications, 11(1) Springer Nature 10.1038/s41467-020-19353-0
Pabis, Marta; Termathe, Martin; Ravichandran, Keerthiraju E; Kienast, Sandra D.; Krutyhołowa, Rościsław; Sokołowski, Mikołaj; Jankowska, Urszula; Grudnik, Przemysław; Leidel, Sebastian A.; Glatt, Sebastian (2020). Molecular basis for the bifunctional Uba4–Urm1 sulfur‐relay system in tRNA thiolation and ubiquitin‐like conjugation. The EMBO journal, 39(19) EMBO Press 10.15252/embj.2020105087
Leiva, Lorenzo Eugenio; Pincheira, Andrea; Elgamal, Sara; Kienast, Sandra D.; Bravo, Verónica; Leufken, Johannes; Gutiérrez, Daniela; Leidel, Sebastian A.; Ibba, Michael; Katz, Assaf (2020). Modulation of Escherichia coli Translation by the Specific Inactivation of tRNAGly Under Oxidative Stress. Frontiers in genetics, 11(856) Frontiers Media SA 10.3389/fgene.2020.00856
Haas, Astrid; Nilges, Benedikt S.; Leidel, Sebastian A.; Klempnauer, Karl-Heinz (2020). PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs. Scientific reports, 10(1), p. 2758. Springer Nature 10.1038/s41598-020-59678-w
Pinto, Rita; Vågbø, Cathrine B; Jakobsson, Magnus E; Kim, Yeji; Baltissen, Marijke P; O’Donohue, Marie-Françoise; Guzmán, Ulises H; Małecki, Jędrzej M; Wu, Jie; Kirpekar, Finn; Olsen, Jesper V; Gleizes, Pierre-Emmanuel; Vermeulen, Michiel; Leidel, Sebastian A; Slupphaug, Geir; Falnes, Pål Ø (2020). The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA. Nucleic acids research, 48(2), pp. 830-846. Oxford University Press 10.1093/nar/gkz1147
Lorent, Julie; Kusnadi, Eric P; Hoef, Vincent; Rebello, Richard J; Leibovitch, Matthew; Ristau, Johannes; Chen, Shan; Lawrence, Mitchell G; Szkop, Krzysztof J; Samreen, Baila; Balanathan, Preetika; Rapino, Francesca; Close, Pierre; Bukczynska, Patricia; Scharmann, Karin; Takizawa, Itsuhiro; Risbridger, Gail P; Selth, Luke A; Leidel, Sebastian A; Lin, Qishan; ... (2019). Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression. The EMBO journal, 38(23), e101323. EMBO Press 10.15252/embj.2018101323
Jacob, Dominik; Thüring, Kathrin; Galliot, Aurellia; Marchand, Virginie; Galvanin, Adeline; Ciftci, Akif; Scharmann, Karin; Stock, Michael; Roignant, Jean-Yves; Leidel, Sebastian Andreas; Motorin, Yuri; Schaffrath, Raffael; Klassen, Roland; Helm, Mark (2019). Absolute Quantification of Noncoding RNA by Microscale Thermophoresis. Angewandte Chemie (International ed.), 58(28), pp. 9565-9569. Wiley-VCH 10.1002/anie.201814377
Ranjan, Namit; Leidel, Sebastian A. (2019). The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS letters, 593(13), pp. 1483-1493. FEBS Press 10.1002/1873-3468.13491
Blasco-Moreno, Bernat; de Campos-Mata, Leire; Böttcher, René; García-Martínez, José; Jungfleisch, Jennifer; Nedialkova, Danny D.; Chattopadhyay, Shiladitya; Gas, María-Eugenia; Oliva, Baldomero; Pérez-Ortín, José E.; Leidel, Sebastian A.; Choder, Mordechai; Díez, Juana (2019). The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins. Nature communications, 10(1) Nature Publishing Group 10.1038/s41467-019-09199-6
de Crécy-Lagard, Valérie; Boccaletto, Pietro; Mangleburg, Carl G; Sharma, Puneet; Lowe, Todd M; Leidel, Sebastian A; Bujnicki, Janusz M (2019). Matching tRNA modifications in humans to their known and predicted enzymes. Nucleic acids research, 47(5), pp. 2143-2159. Oxford University Press 10.1093/nar/gkz011
Sarin, L. Peter; Kienast, Sandra D.; Leufken, Johannes; Ross, Robert L.; Dziergowska, Agnieszka; Debiec, Katarzyna; Sochacka, Elzbieta; Limbach, Patrick A.; Fufezan, Christian; Drexler, Hannes C.A.; Leidel, Sebastian Andreas (2018). Nano LC-MS using capillary columns enables accurate quantification of modified ribonucleosides at low femtomol levels. RNA - a publication of the RNA Society, 24(10), pp. 1403-1417. Cold Spring Harbor Laboratory Press 10.1261/rna.065482.117
Taudière, Adrien; Bellanger, Jean-Michel; Carcaillet, Christopher; Hugot, Laetitia; Kjellberg, Finn; Lecanda, Aarón; Lesne, Annick; Moreau, Pierre-Arthur; Scharmann, Karin; Leidel, Sebastian Andreas; Richard, Franck (2018). Diversity of foliar endophytic ascomycetes in the endemic Corsican pine forests. Fungal ecology, 36, pp. 128-140. Elsevier 10.1016/j.funeco.2018.07.008
Rode, Sandra; Ohm, Henrike; Anhäuser, Lea; Wagner, Marina; Rosing, Mechthild; Deng, Xiaobing; Sin, Olga; Leidel, Sebastian Andreas; Storkebaum, Erik; Rentmeister, Andrea; Zhu, Sijun; Rumpf, Sebastian (2018). Differential Requirement for Translation Initiation Factor Pathways during Ecdysone-Dependent Neuronal Remodeling in Drosophila. Cell reports, 24(9), 2287-2299.e4. Cell Press 10.1016/j.celrep.2018.07.074
Jakobsson, Magnus E.; Małecki, Jędrzej M.; Halabelian, Levon; Nilges, Benedikt S.; Pinto, Rita; Kudithipudi, Srikanth; Munk, Stephanie; Davydova, Erna; Zuhairi, Fawzi R.; Arrowsmith, Cheryl H.; Jeltsch, Albert; Leidel, Sebastian Andreas; Olsen, Jesper V.; Falnes, Pål Ø. (2018). The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates. Nature communications, 9(1) Nature Publishing Group 10.1038/s41467-018-05646-y
Kim, Yeji; Eggers, Cristian; Shvetsova, Ekaterina; Kleemann, Leon; Sin, Olga; Leidel, Sebastian A. (2021). Analysis of codon-specific translation by ribosome profiling. In: Jackman, Jane E. (ed.) RNA Modification Enzymes. Methods in enzymology: Vol. 658 (pp. 191-223). Elsevier 10.1016/bs.mie.2021.06.025