Pichler, Werner Joseph

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Jörg-Walther, Lukas; Schnyder, Benno; Helbling, Arthur; Helsing, Karin; Schüller, Alexandra; Wochner, Annette; Pichler, Werner (2015). Flare-up reactions in severe drug hypersensitivity: infection or ongoing T-cell hyperresponsiveness. Clinical case reports, 3(10), pp. 798-801. Wiley 10.1002/ccr3.346

Wheatley, Lisa M; Plaut, Marshall; Schwaninger, Julie M; Banerji, Aleena; Castells, Mariana; Finkelman, Fred D; Gleich, Gerald J; Guttman-Yassky, Emma; Mallal, Simon A K; Naisbitt, Dean J; Ostrov, David A; Phillips, Elizabeth J; Pichler, Werner Joseph; Platts-Mills, Thomas A E; Roujeau, Jean-Claude; Schwartz, Lawrence B; Trepanier, Lauren A (2015). Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy. Journal of allergy and clinical immunology, 136(2), pp. 262-271. Mosby 10.1016/j.jaci.2015.05.027

Schnyder, B.; Porebski, G.; Pichler, W. J. (2013). Allergy workup of severe cutaneous adverse drug reactions: a light at the end of the tunnel? British journal of dermatology, 168(3), pp. 463-464. Wiley-Blackwell 10.1111/bjd.12253

Pichler, Werner; Ring, Johannes (2013). In Memoriam - A Tribute to Alain L. de Weck. International archives of allergy and immunology, 162(1), pp. 97-98. Karger 10.1159/000351773

Adam, Jacqueline; Wuillemin, Natascha Andrea; Schnyder, K; Yerly, Daniel; Pichler, Werner Joseph; Yawalkar, Nikhil; Schlapbach, Christoph (2013). Possible involvement of Ambroxol as trigger of an erythema exsudativum multiforme majus/Stevens-Johnson Syndrome overlap. Dermatologica Helvetica, 25(6). Karger

Adam, Jacqueline; Wuillemin, Natascha Andrea; Schnyder, K.; Yerly, Daniel; Pichler, Werner Joseph; Yawalkar, Nikhil; Schlapbach, Christoph (2013). CD8+ T cells and NK cells from blister fluid of an EEM/SJS overlap highly express Fas ligand and Granulysin (Unpublished). In: Gemeinsame Jahresversammlung der Schweizerischen Gesellschaft für Allergologie und Immunologie und der Gesellschaft für Pneumologie. Bern. 17. - 19.04.2013.

Pichler, WJ (2007). Hapten-Modell contra p-i-Konzept. Allergo-Journal - interdisziplinäre Zeitschrift für Allergologie und Umweltmedizin, 16(4), pp. 238-239. München: Urban und Vogel 10.1007/BF03371967

Yes

Pichler, Werner Joseph; Adam, Jacqueline; Watkins, Stephen; Wuillemin, Natascha Andrea; Yun, James Jin Sup; Yerly, Daniel (2015). Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors. International archives of allergy and immunology, 168(1), pp. 13-24. Karger 10.1159/000441280

Wuillemin, Natascha Andrea; Terracciano, Luigi; Beltraminelli, Helmut; Schlapbach, Christoph; Fontana, Stefano; Krähenbühl, Stephan; Pichler, Werner Joseph; Yerly, Daniel (2014). T cells infiltrate the liver and kill hepatocytes in HLA-B(∗)57:01-associated floxacillin-induced liver injury. American journal of pathology, 184(6), pp. 1677-1682. Elsevier 10.1016/j.ajpath.2014.02.018

Yun, James Jin Sup; Marcaida, Maria J; Eriksson, Klara K; Jamin, Heidi; Fontana, Stefano; Pichler, Werner Joseph; Yerly, Daniel (2014). Oxypurinol directly and immediately activates the drug-specific T cells via the preferential use of HLA-B*58:01. Journal of immunology, 192(7), pp. 2984-2993. American Association of Immunologists 10.4049/jimmunol.1302306

Srinoulprasert, Yuttana; Pichler, Werner Joseph (2014). Enhancement of Drug-Specific Lymphocyte Proliferation Using CD25-Depleted CD3(+) Effector Cells. International archives of allergy and immunology, 163(3), pp. 198-205. Karger 10.1159/000358491

Demoly, P.; Adkinson, N. F.; Brockow, K.; Castells, M.; Chiriac, A. M.; Greenberger, P. A.; Khan, D. A.; Lang, D. M.; Park, H.-S.; Pichler, Werner Joseph; Sanchez-Borges, M.; Shiohara, T.; Thong, B. Y.-H. (2014). International Consensus on drug allergy. Allergy, 69(4), pp. 420-437. Wiley-Blackwell 10.1111/all.12350

Adam, Jacqueline; Wuillemin, Natascha Andrea; Watkins, Stephan Lloyd; Jamin, Heidi; Eriksson, Klara Kristin; Villiger, Peter; Fontana, Stefano; Pichler, Werner Joseph; Yerly, Daniel (2014). Abacavir induced T cell reactivity from drug naïve individuals shares features of allo-immune responses. PLoS ONE, 9(4), e95339. Public Library of Science 10.1371/journal.pone.0095339

Pichler, Werner Joseph; Watkins, Stephan Lloyd (2014). Interaction of small molecules with specific immune receptors: the p-i concept and its consequences. Current Immunology Reviews, 10(1), pp. 7-18. Bentham Science Publishers

Yun, J,; Mattsson, J,; Schnyder, K,; Fontana, S,; Largiadèr, C, R,; Pichler, W, J,; Yerly, D, (2013). Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response. Clinical and experimental allergy, 43(11), pp. 1246-1255. Blackwell Scientific Publications 10.1111/cea.12184

Pichler, Werner J.; Schnyder, K. (2013). Medikamentenallergie: Diagnostische Möglichkeiten mit In-vitro-Methoden. Allergologie, 36(10), pp. 436-443. Dustri-Verlag 10.5414/ALX01602

Porebski, G.; Pecaric-Petkovic, T.; Groux-Keller, M.; Bosak, M.; Kawabata, T. T.; Pichler, W. J. (2013). In vitro drug causality assessment in Stevens-Johnson syndrome - alternatives for lymphocyte transformation test. Clinical and experimental allergy, 43(9), pp. 1027-1037. Blackwell Scientific Publications 10.1111/cea.12145

Schnyder, Benno; Adam, Jacqueline; Rauch, Andri; Thurnheer, Maria C.; Pichler, Werner J. (2013). Letter to the editor: HLA-B*57:01(+) abacavir-naive individuals have specific T cells but no patch test reactivity. Journal of allergy and clinical immunology, 132(3), pp. 756-758. Mosby 10.1016/j.jaci.2013.04.013

Schnyder, Benno; Pichler, Werner J. (2013). Allergy to sulfonamides. Journal of allergy and clinical immunology, 131(1), 256-257e.5. Mosby 10.1016/j.jaci.2012.10.003

Watkins, Stephan; Pichler, Werner J. (2013). Sulfamethoxazole induces a switch mechanism in T cell receptors containing TCRVβ20-1, altering pHLA recognition. PLoS ONE, 8(10), e76211. Public Library of Science 10.1371/journal.pone.0076211

Pichler, Werner J. (2013). Consequences of drug binding to immune receptors: Immune stimulation following pharmacological interaction with immune receptors (T-cell receptor for antigen or human leukocyte antigen) with altered peptide-human leukocyte antigen or peptide. Dermatologica Sinica, 31(4), pp. 181-190. Elsevier 10.1016/j.dsi.2013.09.005

Watkins, Stephan; Pichler, Werner J. (2013). Activating interactions of sulfanilamides with T cell receptors. Open Journal of Immunology, 3(3), pp. 139-157. Scientific Research Publishing 10.4236/oji.2013.33019

Pichler, Werner J; Daubner, Barbara; Kawabata, Tom (2011). Drug hypersensitivity: flare-up reactions, cross-reactivity and multiple drug hypersensitivity. Journal of dermatology, 38(3), pp. 216-21. Richmond (Aus.): Wiley 10.1111/j.1346-8138.2010.01142.x

McCormack, Mark; Alfirevic, Ana; Bourgeois, Stephane; Farrell, John J; Kasperavičiūtė, Dalia; Carrington, Mary; Sills, Graeme J; Marson, Tony; Jia, Xiaoming; de Bakker, Paul I W; Chinthapalli, Krishna; Molokhia, Mariam; Johnson, Michael R; O'Connor, Gerard D; Chaila, Elijah; Alhusaini, Saud; Shianna, Kevin V; Radtke, Rodney A; Heinzen, Erin L; Walley, Nicole; ... (2011). HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. New England journal of medicine NEJM, 364(12), pp. 1134-43. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMoa1013297

Zawodniak, Anna; Lochmatter, Priska; Yerly, Daniel; Kawabata, Thomas; Lerch, Marianne; Yawalkar, Nikhil; Pichler, Werner Joseph (2010). In vitro detection of cytotoxic T and NK cells in peripheral blood of patients with various drug-induced skin diseases. Allergy, 65(3), pp. 376-384. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.02180.x

Zawodniak, A.; Lochmatter, P.; Beeler, A.; Pichler, W. J. (2010). Cross-reactivity in drug hypersensitivity reactions to sulfasalazine and sulfamethoxazole. International archives of allergy and immunology, 153(2), pp. 152-156. Basel: Karger 10.1159/000312632

Cook, Stéphane; Ladich, Elena; Nakazawa, Gaku; Eshtehardi, Parham; Neidhart, Michel; Vogel, Rolf; Togni, Mario; Wenaweser, Peter; Billinger, Michael; Seiler, Christian; Gay, Steffen; Meier, Bernhard; Pichler, Werner J; Jüni, Peter; Virmani, Renu; Windecker, Stephan (2009). Correlation of intravascular ultrasound findings with histopathological analysis of thrombus aspirates in patients with very late drug-eluting stent thrombosis. Circulation, 120(5), pp. 391-399. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.109.854398

Lochmatter, Priska; Zawodniak, Anna; Pichler, Werner J (2009). In vitro tests in drug hypersensitivity diagnosis. Immunology and allergy clinics of North America, 29(3), pp. 537-54. Philadelphia, Pa.: Elsevier 10.1016/j.iac.2009.04.009

Zawodniak, Anna; Pichler, Werner J. (2009). Immunological Principles of Drug Hypersensitivity. In: Pawankar, Ruby; Holgate, Stephen T.; Rosenwasser, Lanny J. (eds.) Clinical Manifestations. Allergy Frontiers: Vol. 3 (pp. 393-410). Tokyo: Springer 10.1007/978-4-431-88317-3_25

Pichler, Werner J; Beeler, Andreas; Keller, Monika; Lerch, Marianne; Posadas, Sinforiano; Schmid, Daphne; Spanou, Zoi; Zawodniak, Anna; Gerber, Basil (2006). Pharmacological interaction of drugs with immune receptors: the p-i concept. Allergology International, 55(1), pp. 17-25. Carlton (Aus.): Blackwell Science

Gerber, Basil O; Pichler, Werner J (2006). Noncovalent interactions of drugs with immune receptors may mediate drug-induced hypersensitivity reactions. AAPS journal, 8(1), E160-5. Arlington, Va.: Springer-Verlag 10.1208/aapsj080119

Hunziker, Isabelle P.; Grabscheid, Benno; Zurbriggen, Rinaldo; Glück, Reinhard; Pichler, Werner J.; Cerny, Andreas (2002). In vitro studies of core peptide‐bearing immunopotentiating reconstituted influenza virosomes as a non‐live prototype vaccine against hepatitis C virus. International immunology, 14(6), pp. 615-626. Oxford University Press 10.1093/intimm/dxf026

Von Greyerz, Salome; Bültemann, Gregor; Schnyder, Karin; Burkhart, Christoph; Lotti, Barbara; Hari, Yvonne; Pichler, Werner J. (2001). Degeneracy and additional alloreactivity of drug-specific human αβ+ T cell clones. International immunology, 13(7), pp. 877-885. Oxford University Press 10.1093/intimm/13.7.877

Zanni, M P; Von Greyerz, S; Schnyder, B; Wendland, T; Pichler, W J (1998). Allele-unrestricted presentation of lidocaine by HLA-DR molecules to specific alphabeta+ T cell clones. International immunology, 10(4), pp. 507-515. Oxford University Press 10.1093/intimm/10.4.507

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