Roura Padrosa, David

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2024

Roura Padrosa, David; Wetzl, Dennis; Hildbrand, Stefan; Tosatti, Paolo; Sedelmeier, Joerg; Puentener, Kurt; Iding, Hans; Paradisi, Francesca (2024). Biocatalyst Immobilization and Process Intensification: Production of ( S )-Piperazine-2-carboxylic Acid Dihydrochloride. Organic process research & development, 28(5), pp. 1713-1724. ACS Publications 10.1021/acs.oprd.3c00347

2023

Contaldo, Umberto; Roura Padrosa, David; Jamet, Hélène; Albrecht, Martin; Paradisi, Francesca; Le Goff, Alan (2023). Optimising Electrical Interfacing between the Trimeric Copper Nitrite Reductase and Carbon Nanotubes. Chemistry: a European journal, 29(47), e202301351. Wiley 10.1002/chem.202301351

Roura Padrosa, David; Paradisi, Francesca (2023). Bioinformatic analysis of immobilized enzymes: towards a better understanding of the guiding forces. ChemBioChem, 24(11), e202200723. Wiley 10.1002/cbic.202200723

Roura Padrosa, David; Lehmann, Hansjoerg; Snajdrova, Radka; Paradisi, Francesca (2023). Sustainable synthesis of L-phenylalanine derivatives in continuous flow by immobilized phenylalanine ammonia lyase. Frontiers in Catalysis, 3 Frontiers Media 10.3389/fctls.2023.1147205

2022

Benitez-Mateos, Ana I; Klein, Calvin; Roura Padrosa, David; Paradisi, Francesca (2022). A novel thymidine phosphorylase to synthesize (halogenated) anticancer and antiviral nucleoside drugs in continuous flow. Catalysis science & technology, 12(20), pp. 6231-6238. Royal Society of Chemistry 10.1039/D2CY00751G

Benítez-Mateos, Ana I; Roura Padrosa, David; Paradisi, Francesca (2022). Multistep enzyme cascades as a route towards green and sustainable pharmaceutical syntheses. Nature chemistry, 14(5), pp. 489-499. Springer Nature 10.1038/s41557-022-00931-2

Gianolio, Stefania; Roura Padrosa, David; Paradisi, Francesca (2022). Combined chemoenzymatic strategy for sustainable continuous synthesis of the natural product hordenine. Green chemistry, 24(21), pp. 8434-8440. Royal Society of Chemistry 10.1039/D2GC02767D

2021

Marchini, Valentina; Benítez Mateos, Ana I.; Roura Padrosa, David; Paradisi, Francesca (2021). Fusion of Glutamate Dehydrogenase and Formate Dehydrogenase Yields a Bifunctional Efficient Biocatalyst for the Continuous Removal of Ammonia. Frontiers in Catalysis, 1 Frontiers Media 10.3389/fctls.2021.790461

Roura Padrosa, David; Marchini, Valentina; Paradisi, Francesca (2021). CapiPy: python based GUI-application to assist in protein immobilization. Bioinformatics, 37(17), pp. 2761-2762. Oxford University Press 10.1093/bioinformatics/btab030

Roura Padrosa, David; Nisar, Zoya; Paradisi, Francesca (2021). Efficient Amino Donor Recycling in Amination Reactions: Development of a New Alanine Dehydrogenase in Continuous Flow and Dialysis Membrane Reactors. Catalysts, 11(4), p. 520. MDPI 10.3390/catal11040520

Benítez-Mateos, Ana I.; Contente, Martina L.; Roura Padrosa, David; Paradisi, Francesca (2021). Flow biocatalysis 101: design, development and applications. Reaction chemistry & engineering, 6(4), pp. 599-611. Royal Society of Chemistry 10.1039/D0RE00483A

Lenzen, Karst; Planchestainer, Matteo; Feller, Isabelle; Roura Padrosa, David; Paradisi, Francesca; Albrecht, Martin (2021). Minimalistic peptidic scaffolds harbouring an artificial carbene-containing amino acid modulate reductase activity. Chemical communications, 57(72), pp. 9068-9071. Royal Society of Chemistry 10.1039/D1CC03158A

2020

Contente, Martina L.; Fiore, Noemi; Cannazza, Pietro; Roura Padrosa, David; Molinari, Francesco; Gourlay, Louise; Paradisi, Francesca (2020). Uncommon overoxidative catalytic activity in a new halo‐tolerant alcohol dehydrogenase. ChemCatChem, 12(22), pp. 5679-5685. WILEY-VCH 10.1002/cctc.202001112

Roura Padrosa, David; Benítez-Mateos, Ana I.; Calvey, Liam; Paradisi, Francesca (2020). Cell-free biocatalytic syntheses of L-pipecolic acid: a dual strategy approach and process intensification in flow. Green chemistry, 22(16), pp. 5310-5316. Royal Society of Chemistry 10.1039/D0GC01817A

Contente, Martina L.; Roura Padrosa, David; Molinari, Francesco; Paradisi, Francesca (2020). A strategic Ser/Cys exchange in the catalytic triad unlocks an acyltransferase-mediated synthesis of thioesters and tertiary amides. Nature catalysis, 3(12), pp. 1020-1026. Nature Publishing Group 10.1038/s41929-020-00539-0

2019

Roura Padrosa, David; Alaux, Raphael; Smith, Phillip; Dreveny, Ingrid; López-Gallego, Fernando; Paradisi, Francesca (2019). Enhancing PLP-Binding Capacity of Class-III ω-Transaminase by Single Residue Substitution. Frontiers in Bioengineering and Biotechnology, 7(282) Frontiers Media 10.3389/fbioe.2019.00282

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