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Rafiq, Sreoshee; Mungure, Irene; Banz, Yara; Niklaus, Nicolas J.; Kaufmann, Thomas; Müller, Stefan; Jacquel, Arnaud; Robert, Guillaume; Auberger, Patrick; Torbett, Bruce E; Muller, Sylviane; Tschan, Mario P.; Humbert, Magali (2024). HSPA8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation. Pharmacology, 109(4), pp. 216-230. Karger 10.1159/000537864
Mandhair, Harpreet K; Radpour, Ramin; Westerhuis, Mira; Banz, Yara; Humbert, Magali; Arambasic, Miroslav; Dengjel, Jörn; Davies, Andrew; Tschan, Mario P; Novak, Urban (2024). Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach. Leukemia, 38(2), pp. 424-429. Nature Publishing Group 10.1038/s41375-024-02147-4
Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w
Rafiq, Sreoshee; McKenna, Sharon L; Muller, Sylviane; Tschan, Mario; Humbert, Magali (2021). Lysosomes in acute myeloid leukemia: potential therapeutic targets? Leukemia, 35(10), pp. 2759-2770. Springer Nature 10.1038/s41375-021-01388-x
Humbert, Magali; Seiler, Kristina; Mosimann, Severin; Rentsch, Vreni; Sharma, Katyayani; Pandey, Amit Vikram; McKenna, Sharon L.; Tschan, Mario P. (2021). Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy. Cell death and differentiation, 28(8), pp. 2465-2481. Springer Nature 10.1038/s41418-021-00768-1
Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Abildgaard, Marie H; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E; Adeli, Khosrow; Adolph, Timon E; Adornetto, Annagrazia; Aflaki, Elma; Agam, Galila; Agarwal, Anupam; Aggarwal, Bharat B; Agnello, Maria; Agostinis, Patrizia; ... (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), pp. 1-382. Taylor & Francis 10.1080/15548627.2020.1797280
Tokarchuk, Igor; Janser, Félice A.; Schläfli, Anna M.; Pinto, Marta Teixeira; Humbert, Magali; Niklaus, Nicolas J.; Berezowska, Sabina; Langer, Rupert; Tschan, Mario P. (2021). Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability. Biochemical and biophysical research communications, 569, pp. 47-53. Elsevier 10.1016/j.bbrc.2021.06.082
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Humbert, Magali; Morán, María; de la Cruz-Ojeda, Patricia; Muntané, Jordi; Wiedmer, Tabea; Apostolova, Nadezda; McKenna, Sharon L; Velasco, Guillermo; Balduini, Walter; Eckhart, Leopold; Janji, Bassam; Sampaio-Marques, Belém; Ludovico, Paula; Žerovnik, Eva; Langer, Rupert; Perren, Aurel; Engedal, Nikolai; Tschan, Mario (2020). Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot. Biology, 9(3), pp. 1-24. MDPI 10.3390/biology9030059
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Adams, Olivia; Janser, Félice A.; Dislich, Bastian; Berezowska, Sabina; Humbert, Magali; Seiler, Christian A.; Kröll, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario P.; Langer, Rupert (2019). Correction: A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE, 14(10), e0224832. Public Library of Science 10.1371/journal.pone.0224832
Djavaheri-Mergny, Mojgan; Giuriato, Sylvie; Tschan, Mario; Humbert, Magali (2019). Therapeutic Modulation of Autophagy in Leukaemia and Lymphoma. Cells, 8(2) MDPI 10.3390/cells8020103
Niklaus, Nicolas Jan; Humbert, Magali; Tschan, Mario (2018). Cisplatin sensitivity in breast cancer cells is associated with particular DMTF1 splice variant expression. Biochemical and biophysical research communications, 503(4), pp. 2800-2806. Academic Press 10.1016/j.bbrc.2018.08.042
Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795
Adams, Olivia; Janser, Félice A.; Dislich, Bastian; Berezowska, Sabina; Humbert, Magali; Seiler, Christian A.; Kroell, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario P.; Langer, Rupert (2018). A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE, 13(6), e0197610. Public Library of Science 10.1371/journal.pone.0197610
Humbert, Magali; Federzoni, Elena; Tschan, Mario (2017). Distinct TP73-DAPK2-ATG5 pathway involvement in ATO-mediated cell death versus ATRA-mediated autophagy responses in APL. Journal of leukocyte biology, 102(6), pp. 1357-1370. Society for Leukocyte Biology 10.1189/jlb.1A0317-132R
Haimovici, Aladin; Humbert, Magali; Federzoni, Elena A; Shan-Krauer, Deborah; Brunner, Thomas; Frese, Steffen; Kaufmann, Thomas; Torbett, Bruce E; Tschan, Mario (2017). PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell death and differentiation, 24(5), pp. 866-877. Nature Publishing Group 10.1038/cdd.2017.40
Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608
Federzoni, Elena; Humbert, Magali; Torbett, Bruce E; Behre, Gerhard; Fey, Martin; Tschan, Mario (2014). CEBPA-dependent HK3 and KLF5 expression in primary AML and during AML differentiation. Scientific Reports, 4(1), p. 4261. Nature Publishing Group 10.1038/srep04261
Humbert, Magali; Medova, Michaela; Aebersold, Daniel; Blaukat, Andree; Bladt, Friedhelm; Fey, Martin; Zimmer, Yitzhak; Tschan, Mario P. (2013). Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells. Biochemical and biophysical research communications, 431(2), pp. 264-269. Academic Press 10.1016/j.bbrc.2012.12.120
Federzoni, Elena A.; Humbert, Magali; Valk, Peter J. M.; Behre, Gerhard; Leibundgut, Elisabeth O.; Torbett, Bruce E; Fey, Martin F.; Tschan, Mario (2013). The actin-binding protein CORO1A is a novel PU.1 (SPI1)- and CEBPA-regulated gene with significantly lower expression in APL and CEBPA-mutated AML patients. British journal of haematology, 160(6), pp. 855-859. Oxford: Wiley-Blackwell 10.1111/bjh.12170
Humbert, Magali; Mueller, Chantal; Fey, Martin F; Tschan, Mario P (2012). Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells. Leukemia research, 36(12), pp. 1552-6. Amsterdam: Elsevier 10.1016/j.leukres.2012.08.024
Humbert, Magali; Halter, Veronika; Shan, Deborah; Laedrach, Judith; Leibundgut, Elisabeth Oppliger; Baerlocher, Gabriela M; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2011). Deregulated expression of Kruppel-like factors in acute myeloid leukemia. Leukemia research, 35(7), pp. 909-13. Amsterdam: Elsevier 10.1016/j.leukres.2011.03.010
