Locatelli, Giuseppe

Berve, Kristina; Michel, Julia; Tietz, Silvia; Blatti, Claudia; Ivan, Daniela; Enzmann, Gaby; Lyck, Ruth; Deutsch, Urban; Locatelli, Giuseppe; Engelhardt, Britta (2024). Junctional adhesion molecule-A deficient mice are protected from severe experimental autoimmune encephalomyelitis. European journal of immunology, 54(6), e2350761. Wiley-VCH 10.1002/eji.202350761

Wishart, Claire L; Spiteri, Alanna G; Locatelli, Giuseppe; King, Nicholas J C (2023). Integrating transcriptomic datasets across neurological disease identifies unique myeloid subpopulations driving disease-specific signatures. GLIA, 71(4), pp. 904-925. Wiley-Blackwell 10.1002/glia.24314

C Ivan, Daniela; Berve, Kristina Carolin; Walthert, Sabrina; Monaco, Gianni; Borst, Katharina; Bouillet, Elisa; Ferreira, Filipa; Lee, Henry; Steudler, Jasmin; Buch, Thorsten; Prinz, Marco; Engelhardt, Britta; Locatelli, Giuseppe (2023). Insulin-like growth factor-1 receptor controls the function of CNS-resident macrophages and their contribution to neuroinflammation. Acta neuropathologica communications, 11(1), p. 35. 10.1186/s40478-023-01535-8

Locatelli, Giuseppe; Marques-Ferreira, Filipa; Katsoulas, Antonis; Kalaitzaki, Vasileia; Krueger, Martin; Ingold-Heppner, Barbara; Walthert, Sabrina; Sankowski, Roman; Prazeres da Costa, Olivia; Dolga, Amalia; Huber, Magdalena; Gold, Maike; Culmsee, Carsten; Waisman, Ari; Bechmann, Ingo; Milchevskaya, Vladislava; Prinz, Marco; Tresch, Achim; Becher, Burkhard and Buch, Thorsten (2023). IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. GLIA, 71(3), pp. 616-632. Wiley-Blackwell 10.1002/glia.24299

Steudler, Jasmin; Ecott, Timothy; Ivan, Daniela C; Bouillet, Elisa; Walthert, Sabrina; Berve, Kristina; Dick, Tobias P; Engelhardt, Britta; Locatelli, Giuseppe (2022). Autoimmune neuroinflammation triggers mitochondrial oxidation in oligodendrocytes. GLIA, 70(11), pp. 2045-2061. Wiley-Blackwell 10.1002/glia.24235

Guse, Kirsten; Hagemann, Nina; Thiele, Lisa; Remlinger, Jana; Salmen, Anke; Hoepner, Robert; Keller, Irene; Meyer, Patricia; Grandgirard, Denis; Leib, Stephen; Vassella, Erik; Locatelli, Giuseppe; Hermann, Dirk M; Chan, Andrew Hao-Kuang (2022). CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells. Neurology: neuroimmunology & neuroinflammation, 9(4) Wolters Kluwer Health 10.1212/NXI.0000000000001168

Spiteri, Alanna G; Wishart, Claire L; Pamphlett, Roger; Locatelli, Giuseppe; King, Nicholas J C (2022). Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function. Acta neuropathologica, 143(2), pp. 179-224. Springer-Verlag 10.1007/s00401-021-02384-2

Loy, Kristina; Fourneau, Julie; Meng, Ning; Denecke, Carmen; Locatelli, Giuseppe; Bareyre, Florence M (2021). Semaphorin 7A restricts serotonergic innervation and ensures recovery after spinal cord injury. Cellular and molecular life sciences : CMLS, 78(6), pp. 2911-2927. Springer 10.1007/s00018-020-03682-w

Ivan, Daniela C.; Walthert, Sabrina; Berve, Kristina; Steudler, Jasmin; Locatelli, Giuseppe (2021). Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System. Frontiers in immunology, 11, p. 609921. Frontiers Research Foundation 10.3389/fimmu.2020.609921

Weber, Florian; C. Ivan, Daniela; Proulx, Steven T.; Locatelli, Giuseppe; Aleandri, Simone; Luciani, Paola (2021). Beyond Trial and Error: A Systematic Development of Liposomes Targeting Primary Macrophages. Advanced nanoBiomed research, 1(3), p. 2000098. Wiley 10.1002/anbr.202000098

Ivan, Daniela C.; Walthert, Sabrina; Locatelli, Giuseppe (2021). Central Nervous System Barriers Impact Distribution and Expression of iNOS and Arginase-1 in Infiltrating Macrophages During Neuroinflammation. Frontiers in immunology, 12 Frontiers Research Foundation 10.3389/fimmu.2021.666961

Locatelli, Giuseppe; Engelhardt, Britta (2020). Microglia Get a Little Help from "Th"-eir Friends. Immunity, 53(3), pp. 484-486. Cell Press 10.1016/j.immuni.2020.08.011

Jordão, Marta Joana Costa; Sankowski, Roman; Brendecke, Stefanie M; Sagar, PhD; Locatelli, Giuseppe; Tai, Yi-Heng; Tay, Tuan Leng; Schramm, Eva; Armbruster, Stephan; Hagemeyer, Nora; Groß, Olaf; Mai, Dominic; Çiçek, Özgün; Falk, Thorsten; Kerschensteiner, Martin; Grün, Dominic; Prinz, Marco (2019). Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation. Science, 363(6425) American Association for the Advancement of Science 10.1126/science.aat7554

Locatelli, Giuseppe; Theodorou, Delphine; Kendirli, Arek; Jordão, Marta Joana Costa; Staszewski, Ori; Phulphagar, Kshiti; Cantuti-Castelvetri, Ludovico; Dagkalis, Athanasios; Bessis, Alain; Simons, Mikael; Meissner, Felix; Prinz, Marco; Kerschensteiner, Martin (2018). Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model. Nature neuroscience, 21(9), pp. 1196-1208. Nature America 10.1038/s41593-018-0212-3

Bouattour, Mohamed; Raymond, Eric; Qin, Shukui; Cheng, Ann-Lii; Stammberger, Uz; Locatelli, Giuseppe; Faivre, Sandrine (2018). Recent developments of c-Met as a therapeutic target in hepatocellular carcinoma. Hepatology, 67(3), pp. 1132-1149. Wiley 10.1002/hep.29496

Wu, Yi-Long; Soo, Ross Andrew; Locatelli, Giuseppe; Stammberger, Uz; Scagliotti, Giorgio; Park, Keunchil (2017). Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? Cancer treatment reviews, 61, pp. 70-81. Elsevier 10.1016/j.ctrv.2017.10.003

Friese-Hamim, Manja; Bladt, Friedhelm; Locatelli, Giuseppe; Stammberger, Uz; Blaukat, Andree (2017). The selective c-Met inhibitor tepotinib can overcome epidermal growth factor receptor inhibitor resistance mediated by aberrant c-Met activation in NSCLC models. American journal of cancer research, 7(4), pp. 962-972. e-Century Publishing Corporation

Goldmann, Tobias; Wieghofer, Peter; Jordão, Marta Joana Costa; Prutek, Fabiola; Hagemeyer, Nora; Frenzel, Kathrin; Amann, Lukas; Staszewski, Ori; Kierdorf, Katrin; Krueger, Martin; Locatelli, Giuseppe; Hochgerner, Hannah; Zeiser, Robert; Epelman, Slava; Geissmann, Frederic; Priller, Josef; Rossi, Fabio M V; Bechmann, Ingo; Kerschensteiner, Martin; Linnarsson, Sten; ... (2016). Origin, fate and dynamics of macrophages at central nervous system interfaces. Nature immunology, 17(7), pp. 797-805. Nature Publishing Group 10.1038/ni.3423

Fujikawa, Yuuta; Roma, Leticia P; Sobotta, Mirko C; Rose, Adam J; Diaz, Mauricio Berriel; Locatelli, Giuseppe; Breckwoldt, Michael O; Misgeld, Thomas; Kerschensteiner, Martin; Herzig, Stephan; Müller-Decker, Karin; Dick, Tobias P (2016). Mouse redox histology using genetically encoded probes. Science signaling, 9(419), rs1. American Association for the Advancement of Science 10.1126/scisignal.aad3895

Locatelli, Giuseppe; Baggiolini, Arianna; Schreiner, Bettina; Palle, Pushpalatha; Waisman, Ari; Becher, Burkhard; Buch, Thorsten (2015). Mature oligodendrocytes actively increase in vivo cytoskeletal plasticity following CNS damage. Journal of neuroinflammation, 12(62), p. 62. BioMed Central 10.1186/s12974-015-0271-2

Schreiner, Bettina; Ingold-Heppner, Barbara; Pehl, Debora; Locatelli, Giuseppe; Berrit-Schönthaler, Helia; Becher, Burkhard (2015). Deletion of Jun proteins in adult oligodendrocytes does not perturb cell survival, or myelin maintenance in vivo. PLoS ONE, 10(3), e0120454. Public Library of Science 10.1371/journal.pone.0120454

Locatelli, Giuseppe; Wörtge, Simone; Buch, Thorsten; Ingold, Barbara; Frommer, Friederike; Sobottka, Bettina; Krüger, Martin; Karram, Khalad; Bühlmann, Claudia; Bechmann, Ingo; Heppner, Frank L; Waisman, Ari; Becher, Burkhard (2012). Primary oligodendrocyte death does not elicit anti-CNS immunity. Nature neuroscience, 15(4), pp. 543-550. Nature America 10.1038/nn.3062