Potempa, Jan

Wielento, Aleksandra; Bereta, Grzegorz P; Łagosz-Ćwik, Katarzyna B; Eick, Sigrun; Lamont, Richard J; Grabiec, Aleksander M; Potempa, Jan (2022). TLR2 Activation by Porphyromonas gingivalis Requires Both PPAD Activity and Fimbriae. Frontiers in immunology, 13, p. 823685. Frontiers Research Foundation 10.3389/fimmu.2022.823685

Taudte, Nadine; Linnert, Miriam; Rahfeld, Jens-Ulrich; Piechotta, Anke; Ramsbeck, Daniel; Buchholz, Mirko; Kolenko, Petr; Parthier, Christoph; Houston, John A; Veillard, Florian; Eick, Sigrun; Potempa, Jan; Schilling, Stephan; Demuth, Hans-Ulrich; Stubbs, Milton T (2021). Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis. The journal of biological chemistry, 296, p. 100263. American Society for Biochemistry and Molecular Biology 10.1016/j.jbc.2021.100263

Möller, Burkhard; Bender, Philip; Eick, Sigrun; Kuchen, Stefan; Maldonado, Alejandra; Potempa, Jan; Reichenbach, Stephan; Sculean, Anton; Schwenzer, Anja; Villiger, Peter M.; Wong, Alicia; Midwood, Kim S (2020). Treatment of severe periodontitis may improve clinical disease activity in otherwise treatment-refractory rheumatoid arthritis patients. Rheumatology, 59(1), pp. 243-245. Oxford University Press 10.1093/rheumatology/kez287

Eick, Sigrun; Gadzo, Naida; Tacchi, Manuel; Sculean, Anton; Potempa, Jan; Stavropoulos, Andreas (2019). Gingipains impair attachment of epithelial cell to dental titanium abutment surfaces. Journal of biomedical materials research. Part B - applied biomaterials, 107(8), pp. 2549-2556. John Wiley & Sons 10.1002/jbm.b.34345

Bryzek, Danuta; Ciaston, Izabela; Dobosz, Ewelina; Gasiorek, Anna; Makarska, Anna; Sarna, Michal; Eick, Sigrun; Puklo, Magdalena; Lech, Maciej; Potempa, Barbara; Potempa, Jan; Koziel, Joanna (2019). Triggering NETosis via protease-activated receptor (PAR)-2 signaling as a mechanism of hijacking neutrophils function for pathogen benefits. PLoS pathogens, 15(5), e1007773. Public Library of Science 10.1371/journal.ppat.1007773

Bender, Philip; Egger, Andreas; Westermann, Martin; Taudte, Nadine; Sculean, Anton; Potempa, Jan; Möller, Burkhard; Buchholz, Mirko; Eick, Sigrun (2019). Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis-A pilot study. Archives of oral biology, 97, pp. 223-230. Elsevier Science 10.1016/j.archoralbio.2018.10.022

Laugisch, Oliver; Johnen, Andreas; Maldonado, Alejandra; Ehmke, Benjamin; Bürgin, Walter; Olsen, Ingar; Potempa, Jan; Sculean, Anton; Duning, Thomas; Eick, Sigrun (2018). Periodontal Pathogens and Associated Intrathecal Antibodies in Early Stages of Alzheimer's Disease. Journal of Alzheimer's disease, 66(1), pp. 105-114. IOS Press 10.3233/JAD-180620

Schwenzer, Anja; Quirke, Anne-Marie; Marzeda, Anna M; Wong, Alicia; Montgomery, Anna B; Sayles, Harlan R; Eick, Sigrun; Gawron, Katarzyna; Chomyszyn-Gajewska, Maria; Łazarz-Bartyzel, Katarzyna; Davis, Simon; Potempa, Jan; Kessler, Benedikt M; Fischer, Roman; Venables, Patrick J; Payne, Jeffrey B; Mikuls, Ted R; Midwood, Kim S (2017). Association of Distinct Fine Specificities of Anti-Citrullinated Peptide Antibodies With Elevated Immune Responses to Prevotella intermedia in a Subgroup of Patients With Rheumatoid Arthritis and Periodontitis. Arthritis & rheumatology, 69(12), pp. 2303-2313. Wiley-Blackwell 10.1002/art.40227

Godlewska, Urszula; Brzoza, Piotr; Sroka, Aneta; Majewski, Pawel; Jentsch, Holger; Eckert, Martin; Eick, Sigrun; Potempa, Jan; Zabel, Brian A; Cichy, Joanna (2017). Antimicrobial and Attractant Roles for Chemerin in the Oral Cavity during Inflammatory Gum Disease. Frontiers in immunology, 8, p. 353. Frontiers Research Foundation 10.3389/fimmu.2017.00353

Jusko, Monika; Miedziak, Beata; Ermert, David; Magda, Michal; King, Ben C; Bielecka, Ewa; Riesbeck, Kristian; Eick, Sigrun; Potempa, Jan; Blom, Anna M (2016). FACIN, a Double-Edged Sword of the Emerging Periodontal Pathogen Filifactor alocis: A Metabolic Enzyme Moonlighting as a Complement Inhibitor. Journal of immunology, 197(8), pp. 3245-3259. American Association of Immunologists 10.4049/jimmunol.1600739

Laugisch, Oliver; Wong, Alicia; Sroka, Aneta; Kantyka, Tomasz; Koziel, Joanna; Neuhaus, Klaus; Sculean, Anton; Venables, Patrick J; Potempa, Jan; Möller, Burkhard; Eick, Sigrun (2016). Citrullination in the periodontium-a possible link between periodontitis and rheumatoid arthritis. Clinical oral investigations, 20(4), pp. 675-683. Springer 10.1007/s00784-015-1556-7

Jusko, Monika; Potempa, Jan; Mizgalska, Danuta; Bielecka, Ewa; Ksiazek, Miroslaw; Riesbeck, Kristian; Garred, Peter; Eick, Sigrun; Blom, Anna M (2015). A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System. Journal of immunology, 195(5), pp. 2231-2240. American Association of Immunologists 10.4049/jimmunol.1402892

Ksiazek, Miroslaw; Mizgalska, Danuta; Eick, Sigrun; Thøgersen, Ida B; Enghild, Jan J; Potempa, Jan (2015). KLIKK proteases of Tannerella forsythia: putative virulence factors with a unique domain structure. Frontiers in Microbiology, 6(312), p. 312. Frontiers 10.3389/fmicb.2015.00312

Eick, Sigrun; Puklo, Magdalena; Adamowicz, Karina; Kantyka, Tomasz; Hiemstra, Pieter; Stennicke, Henning; Guentsch, Arndt; Schacher, Beate; Eickholz, Peter; Potempa, Jan (2014). Lack of cathelicidin processing in Papillon-Lefèvre syndrome patients reveals essential role of LL-37 in periodontal homeostasis. Orphanet journal of rare diseases, 9, p. 148. BioMed Central 10.1186/s13023-014-0148-y

Fröhlich, Esther; Kantyka, Tomasz; Plaza, Karolina; Schmidt, Karl-Hermann; Pfister, Wolfgang; Potempa, Jan; Eick, Sigrun (2013). Benzamidine derivatives inhibit the virulence of Porphyromonas gingivalis. Molecular oral microbiology, 28(3), pp. 192-203. Wiley-Blackwell 10.1111/omi.12015

Ruggiero, Sabrina; Cosgarea, Raluca; Potempa, Jan; Potempa, Barbara; Eick, Sigrun; Chiquet, Matthias (2013). Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C. Biochimica et biophysica acta - molecular basis of disease, 1832(4), pp. 517-26. Elsevier 10.1016/j.bbadis.2013.01.003

Guentsch, Arndt; Hirsch, C; Pfister, Wolfgang; Vincents, Bjarne; Abrahamson, Magnus; Sroka, Aneta; Potempa, Jan; Eick, Sigrun (2013). Cleavage of IgG1 in gingival crevicular fluid is associated with the presence of Porphyromonas gingivalis. Journal of periodontal research, 48(4), pp. 458-465. Frederiksberg (DK): Wiley-Blackwell 10.1111/jre.12027

Zdzalik, Michal; Karim, Abdulkarim Y; Wolski, Krzysztof; Buda, Pawel; Wojcik, Kinga; Brueggemann, Sarah; Wojciechowski, Piotr; Eick, Sigrun; Calander, Ann-Marie; Jonsson, Ing-Marie; Kubica, Malgorzata; Polakowska, Klaudia; Miedzobrodzki, Jacek; Wladyka, Benedykt; Potempa, Jan; Dubin, Grzegorz (2012). Prevalence of genes encoding extracellular proteases in Staphylococcus aureus - important targets triggering immune response in vivo. FEMS immunology and medical microbiology, 66(2), pp. 220-9. Oxford: Blackwell 10.1111/j.1574-695X.2012.01005.x

Malm, Sven; Jusko, Monika; Eick, Sigrun; Potempa, Jan; Riesbeck, Kristian; Blom, Anna M. (2012). Acquisition of complement inhibitor serine protease factor I and its cofactors C4b-binding protein and factor H by Prevotella intermedia. PLoS ONE, 7(4), e34852. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0034852

Jusko, Monika; Potempa, Jan; Karim, Abdulkarim Y; Ksiazek, Miroslaw; Riesbeck, Kristian; Garred, Peter; Eick, Sigrun; Blom, Anna M (2012). A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system. Journal of immunology, 188(5), pp. 2338-49. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1101240

Rapala-Kozik, Maria; Bras, Grazyna; Chruscicka, Barbara; Karkowska-Kuleta, Justyna; Sroka, Aneta; Herwald, Heiko; Nguyen, Ky-Anh; Eick, Sigrun; Potempa, Jan; Kozik, Andrzej (2011). Adsorption of Components of the Plasma Kinin-forming System on the Surface of Porphyromonas gingivalis Involves Gingipains as the Major Docking Platforms. Infection and immunity, 79(2), pp. 797-805. New York, N.Y.: American Society for Microbiology 10.1128/IAI.00966-10

Vincents, Bjarne; Guentsch, Arndt; Kostolowska, Dominika; von Pawel-Rammingen, Ulrich; Eick, Sigrun; Potempa, Jan; Abrahamson, Magnus (2011). Cleavage of IgG1 and IgG3 by gingipain K from Porphyromonas gingivalis may compromise host defense in progressive periodontitis. FASEB journal, 25(10), pp. 3741-50. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.11-187799

Guentsch, Arndt; Kramesberger, Martin; Sroka, Aneta; Pfister, Wolfgang; Potempa, Jan; Eick, Sigrun (2011). Comparison of gingival crevicular fluid sampling methods in patients with severe chronic periodontitis. Journal of periodontology, 82(7), pp. 1051-60. Chicago, Ill.: American Academy of Periodontology 10.1902/jop.2011.100565