Nasal microbiota composition dynamics after occupational change in animal farmers suggest major shifts

Kraemer, Julia G.; Aebi, Suzanne; Hilty, Markus; Oppliger, Anne (2021). Nasal microbiota composition dynamics after occupational change in animal farmers suggest major shifts. Science of the total environment, 782(146842), p. 146842. Elsevier 10.1016/j.scitotenv.2021.146842

[img] Text
1-s2.0-S0048969721019124-main.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (801kB) | Request a copy
[img] Text
text-Stoten_revised.pdf - Accepted Version
Restricted to registered users only until 30 May 2023.
Available under License Publisher holds Copyright.

Download (966kB) | Request a copy

Previous studies have suggested a significantly higher diversity in the nasal microbiota of pig farmers compared to people having no contact with farm animals. However, the fate of this nasal microbiota specificity after farmers stop being in contact with the pig farm environment is unknown. The aim of this study was to investigate the change in the nasal microbiota of pig-farmers after the change of occupation.
Methods

Anterior and posterior nasal swabs were collected from seven people during employment on pig farms, and again after a period of at least 50 days after leaving the pig farm. Illumina MiSeq sequencing of 16S rRNA was conducted to characterize the dynamics of the nasal microbiota. The microbiota of actively working pig farmers was compared to microbiota after they had stopped working (ex-pig-farmers) and to control groups (cow farmers and non-exposed individuals).
Results

Following a prolonged period without exposure to pigs, α-diversity of both anterior and posterior cavities dropped significantly. The composition of the microbiota of pig-farmers had a low inter-similarity with the non-exposed group while ex-pig-farmers were more similar to cow-farmers and the non-exposed group than to their own microbiota during pig farming.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Research
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Bacteriology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Bacteriology (Specialist Field)

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Krämer, Julia Gabriele; Aebi, Susanne and Hilty, Markus

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0048-9697

Publisher:

Elsevier

Funders:

[42] Schweizerischer Nationalfonds

Language:

English

Submitter:

Markus Hilty

Date Deposited:

10 Nov 2021 11:18

Last Modified:

14 Nov 2021 01:44

Publisher DOI:

10.1016/j.scitotenv.2021.146842

PubMed ID:

33838360

BORIS DOI:

10.48350/159188

URI:

https://boris.unibe.ch/id/eprint/159188

Actions (login required)

Edit item Edit item
Provide Feedback