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Rousson, Valentin; Ackermann, Daniel; Ponte, Belen; Pruijm, Menno; Guessous, Idris; d'Uscio, Claudia H; Ehret, Georg; Escher, Geneviève; Pechère-Bertschi, Antoinette; Groessl, Michael; Martin, Pierre-Yves; Burnier, Michel; Dick, Bernhard; Bochud, Murielle; Vogt, Bruno; Dhayat, Nasser A. (2021). Sex- and age-specific reference intervals for diagnostic ratios reflecting relative activity of steroidogenic enzymes and pathways in adults. PLoS ONE, 16(7), e0253975. Public Library of Science 10.1371/journal.pone.0253975
Mulatero, Paolo; Wuerzner, Gregoire; Groessl, Michael; Sconfienza, Elisa; Damianaki, Aikaterini; Forestiero, Vittorio; Vogt, Bruno; Brunner, Hans; Gerlock, Teresa; Steele, Ronald; Schumacher, Christoph (2024). Safety and efficacy of once-daily dexfadrostat phosphate in patients with primary aldosteronism: a randomised, parallel group, multicentre, phase 2 trial. EClinicalMedicine, 71(102576) Elsevier 10.1016/j.eclinm.2024.102576
Durrer, Isabelle; Ackermann, Daniel; Klossner, Rahel; Grössl, Michael; Vögel, Clarissa; du Toit, Therina; Vogt, Bruno; Jamin, Heidi; Mohaupt, Markus; Gennari-Moser, Carine (2024). No extra-adrenal aldosterone production in various human cell lines. Journal of molecular endocrinology, 72(3) Journal of Endocrinology 10.1530/JME-23-0100
Pignatti, Emanuele; Kollar, Jakub; Hafele, Evelyn; Schuster, Daniela; Steele, Ronald E; Vogt, Bruno; Schumacher, Christoph; Groessl, Michael (2023). Structural and Clinical Characterization of CYP11B2 Inhibition by Dexfadrostat Phosphate. The journal of steroid biochemistry and molecular biology, 235(106409), p. 106409. Elsevier 10.1016/j.jsbmb.2023.106409
Altinkilic, Emre Murat; du Toit, Therina; Sakin, Önder; Attar, Rukset; Groessl, Michael; Flück, Christa E. (2023). The serum steroid signature of PCOS hints at the involvement of novel pathways for excess androgen biosynthesis. The journal of steroid biochemistry and molecular biology, 233, p. 106366. Elsevier 10.1016/j.jsbmb.2023.106366
Mulatero, Paolo; Groessl, Michael; Vogt, Bruno; Schumacher, Christoph; Steele, Ronald Edward; Brooks, Ashley; Hossack, Stuart; Brunner, Hans-Rudolf (2023). CYP11B2 Inhibitor Dexfadrostat Phosphate Suppresses the Aldosterone-to-Renin Ratio, an Indicator of Sodium Retention, in Healthy Volunteers. British journal of clinical pharmacology, 89(8), pp. 2483-2496. Wiley-Blackwell 10.1111/bcp.15713
Groessl, Michael; Vogt, Bruno (2022). Mass spectrometry imaging and its place in nephrology. Nephrology, dialysis, transplantation, 37(12), pp. 2363-2365. Oxford University Press 10.1093/ndt/gfab359
Flück, Christa E; Kuiri-Hänninen, Tanja; Silvennoinen, Sanna; Sankilampi, Ulla; Groessl, Michael (2022). The androgen metabolome of preterm infants reflects fetal adrenal gland involution. The journal of clinical endocrinology and metabolism, 107(11), pp. 3111-3119. Oxford University Press 10.1210/clinem/dgac482
Andrieu, Thomas; du Toit, Therina; Vogt, Bruno; Mueller, Michael D; Groessl, Michael (2022). Parallel targeted and non-targeted quantitative analysis of steroids in human serum and peritoneal fluid by liquid chromatography high-resolution mass spectrometry. Analytical and bioanalytical chemistry, 414(25), pp. 7461-7472. Springer 10.1007/s00216-022-03881-3
Pignatti, Emanuele; Altinkiliç, Emre Murat; Bräutigam, Konstantin; Grössl, Michael; Perren, Aurel; Zavolan, Mihaela; Flück, Christa E (2022). Cholesterol deprivation drives DHEA biosynthesis in human adrenals. Endocrinology, 163(7) Endocrine Society 10.1210/endocr/bqac076
Magyar, Benjamin P; Santi, Maristella; Sommer, Grit; Nuoffer, Jean-Marc; Leichtle, Alexander; Grössl, Michael; Fluck, Christa E (2022). Short-Term Fasting Attenuates Overall Steroid Hormone Biosynthesis in Healthy Young Women. Journal of the Endocrine Society, 6(7), bvac075. Oxford University Press 10.1210/jendso/bvac075
Moor, Matthias B.; Dhayat, Nasser A.; Schietzel, Simeon; Grössl, Michael; Vogt, Bruno; Fuster, Daniel G. (2022). Urinary tetrahydroaldosterone is associated with circulating FGF23 in kidney stone formers. Urolithiasis, 50(3), pp. 333-340. Springer 10.1007/s00240-022-01317-2
Kocher, Gregor J; Koss, Abigail R; Groessl, Michael; Schefold, Joerg C; Luedi, Markus M; Quapp, Christopher; Dorn, Patrick; Lutz, Jon; Cappellin, Luca; Hutterli, Manuel; Lopez-Hilfiker, Felipe D; Al-Hurani, Mohammad; Sesia, Sergio B (2022). Electrocautery smoke exposure and efficacy of smoke evacuation systems in minimally invasive and open surgery: a prospective randomized study. Scientific reports, 12(1), p. 4941. Springer Nature 10.1038/s41598-022-08970-y
Herzig, David; Groessl, Michael; Álvarez-Martínez, Mario; Reverter-Branchat, Gemma; Nakas, Christos T.; Kosinski, Christophe; Stettler, Christoph; Bally, Lia (2021). Effects of Aerobic Exercise on Systemic Insulin Degludec Concentrations in People With Type 1 Diabetes. Journal of diabetes science and technology, 17(1), pp. 172-175. Sage 10.1177/19322968211043915
Klossner, Rahel; Groessl, Michael; Schumacher, Nadine; Fux, Michaela; Escher, Geneviève; Verouti, Sophia; Jamin, Heidi; Vogt, Bruno; Mohaupt, Markus G; Gennari-Moser, Carine (2021). Steroid hormone bioavailability is controlled by the lymphatic system. Scientific reports, 11(1), p. 9666. Springer Nature 10.1038/s41598-021-88508-w
Karahoda, Rona; Kallol, Sampada; Groessl, Michael; Ontsouka, Edgar; Anderle, Pascale; Fluck, Christa; Staud, Frantisek; Albrecht, Christiane (2021). Revisiting Steroidogenic Pathways in the Human Placenta and Primary Human Trophoblast Cells. International journal of molecular sciences, 22(4) MDPI 10.3390/ijms22041704
Meunier, Solène; Groessl, Michael; Reusch, Claudia; Boretti, Felicitas; Sieber-Ruckstuhl, Nadja (2021). Salivary cortisol in healthy dogs: a randomized cross-over study to evaluate different saliva stimulation methods and their effects on saliva volume and cortisol concentration. BMC veterinary research, 17(1), p. 194. BioMed Central 10.1186/s12917-021-02890-1
Janner, Marco; Sommer, Grit; Groessl, Michael; Flück, Christa E. (2020). Premature Adrenarche in Girls Characterized By Enhanced 17,20-Lyase and 17β-Hydroxysteroid Dehydrogenase Activities. Journal of clinical endocrinology and metabolism, 105(12), e4439-e4451. Endocrine Society 10.1210/clinem/dgaa598
Reverter-Branchat, Gemma; Groessl, Michael; Nakas, Christos T; Prost, Jean-Christophe; Antwi, Kwasi; Niederkofler, Eric E; Bally, Lia (2020). Rapid quantification of insulin degludec by immunopurification combined with liquid chromatography high-resolution mass spectrometry. Analytical and bioanalytical chemistry, 412(30), pp. 8351-8359. Springer 10.1007/s00216-020-02971-4
Sauer, F. J.; Gerber, V.; Frei, S.; Bruckmaier, R. M.; Grössl, M. (2020). Salivary cortisol measurement in horses: immunoassay or LC-MS/MS? Domestic animal endocrinology, 72, p. 106445. Elsevier 10.1016/j.domaniend.2020.106445
Baechler, Fabio; Stettler, Christoph; Vogt, Bruno; Bally, Lia; Groessl, Michael (2020). Concentration and Chemical Stability of Commercially Available Insulins: A High-Resolution Mass Spectrometry Study. Diabetes technology & therapeutics, 22(4), pp. 326-329. Mary Ann Liebert 10.1089/dia.2019.0412
Katharopoulos, Efstathios; Di Iorgi, Natascia; Fernandez-Alvarez, Paula; Pandey, Amit V.; Groessl, Michael; Dubey, Shraddha; Camats, Núria; Napoli, Flavia; Patti, Giuseppa; Lezzi, Marilea; Maghnie, Mohamad; Flück, Christa E. (2020). Characterization of Two Novel Variants of the Steroidogenic Acute Regulatory Protein Identified in a Girl with Classic Lipoid Congenital Adrenal Hyperplasia. International journal of molecular sciences, 21(17), p. 6185. MDPI 10.3390/ijms21176185
Ackermann, Daniel; Escher, Geneviève; d'Uscio, Claudia Henriette; Grössl, Michael; Vogt, Bruno; Dhayat, Nasser (2019). Urinary sex steroid and glucocorticoid hormones are associated with muscle mass and strength in healthy adults. The journal of clinical endocrinology and metabolism, 104(6), pp. 2195-2215. Oxford University Press 10.1210/jc.2018-01942
Ackermann, Daniel; Grössl, Michael; Pruijm, Menno; Ponte, Belen; Escher, Geneviève; d'Uscio, Claudia Henriette; Guessous, Idris; Ehret, Georg; Pechère-Bertschi, Antoinette; Martin, Pierre-Yves; Burnier, Michel; Dick, Bernhard; Vogt, Bruno; Bochud, Murielle; Rousson, Valentin; Dhayat, Nasser (2019). Reference intervals for the urinary steroid metabolome: The impact of sex, age, day and night time on human adult steroidogenesis. PLoS ONE, 14(3), e0214549. Public Library of Science 10.1371/journal.pone.0214549
Bileck, Andrea; Flück Pandey, Christa Emma; Dhayat, Nasser; Grössl, Michael (2019). How high-resolution techniques enable reliable steroid identification and quantification. Journal of steroid biochemistry and molecular biology, 186, pp. 74-78. Elsevier 10.1016/j.jsbmb.2018.09.018
Malikova, Jana; Zingg, Tanja; Fingerhut, Ralph; Sluka, Susanna; Grössl, Michael; Brixius-Anderko, Simone; Bernhardt, Rita; McDougall, Jane; Pandey, Amit Vikram; Flück, Christa Emma (2019). HIV Drug Efavirenz Inhibits CYP21A2 Activity with Possible Clinical Implications. Hormone research in paediatrics, 91(4), pp. 262-270. Karger 10.1159/000500522
Schuhmann, Kai; Moon, HongKee; Thomas, Henrik; Ackerman, Jacobo Miranda; Groessl, Michael; Wagner, Nicolai; Kellmann, Markus; Henry, Ian; Nadler, André; Shevchenko, Andrej (2019). Quantitative Fragmentation Model for Bottom-Up Shotgun Lipidomics. Analytical chemistry, 91(18), pp. 12085-12093. American Chemical Society 10.1021/acs.analchem.9b03270
Lavanant, Hélène; Groessl, Michael; Afonso, Carlos (2019). Collision cross sections of negative cluster ions of phosphoric acid in N2 determined by drift tube ion mobility and their use in travelling wave ion mobility. International journal of mass spectrometry, 442, pp. 14-22. Elsevier 10.1016/j.ijms.2019.04.009
Dhayat, Nasser; Marti, Nesa Magdalena; Kollmann, Zahraa; Bally, Lia; Escher, Geneviève; Grössl, Michael; Ackermann, Daniel; Mueller, Michael; Vogt, Bruno; Birkhäuser, Martin; Flück Pandey, Christa Emma (2018). Urinary steroid profiling in women hints at a diagnostic signature of the polycystic ovary syndrome: A pilot study considering neglected steroid metabolites. PLoS ONE, 13(10), e0203903. Public Library of Science 10.1371/journal.pone.0203903
Bileck, Andrea; Verouti, Sophia N; Escher, Geneviève; Vogt, Bruno; Grössl, Michael (2018). A comprehensive urinary steroid analysis strategy using two-dimensional gas chromatography - time of flight mass spectrometry. Analyst, 143(18), pp. 4484-4494. Royal Society of Chemistry 10.1039/c7an01990d
Hädener, Marianne; Kamrath, Michael Z; Weinmann, Wolfgang; Groessl, Michael (2018). High-Resolution Ion Mobility Spectrometry for Rapid Cannabis Potency Testing. Analytical chemistry, 90(15), pp. 8764-8768. American Chemical Society 10.1021/acs.analchem.8b02180
Cubo, Leticia; Grössl, Michael; Dyson, Paul J.; Quiroga, Adoración G.; Navarro-Ranninger, Carmen; Casini, Angela (2010). Proteins as Possible Targets for Cytotoxic trans-Platinum(II) Complexes with Aliphatic Amine Ligands: Further Exceptions to the DNA Paradigm. ChemMedChem, 5(8), pp. 1335-1343. Wiley-VCH 10.1002/cmdc.201000104
Bytzek, Anna K.; Reithofer, Michael R.; Galanski, Markus; Grössl, Michael; Keppler, Bernhard K.; Hartinger, Christian G. (2010). The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes. Electrophoresis, 31(7), pp. 1144-1150. Wiley-VCH 10.1002/elps.200900522
Grössl, Michael; Tsybin, Yury O.; Hartinger, Christian G.; Keppler, Bernhard K.; Dyson, Paul J. (2010). Ruthenium versus platinum: interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry. Journal of biological and inorganic chemistry JBIC, 15(5), pp. 677-688. Springer-Verlag 10.1007/s00775-010-0635-0
Stojanovic, Anja; Kogelnig, Daniel; Fischer, Lisa; Hann, Stephan; Galanski, Markus; Grössl, Michael; Krachler, Regina; Keppler, Bernhard K. (2010). Phosphonium and Ammonium Ionic Liquids with Aromatic Anions: Synthesis, Properties, and Platinum Extraction. Australian journal of chemistry, 63(3), pp. 511-524. CSIRO Publishing 10.1071/ch09340
Grössl, Michael; Bytzek, Anna; Hartinger, Christian G. (2009). The serum protein binding of pharmacologically active gallium(III) compounds assessed by hyphenated CE-MS techniques. Electrophoresis, 30(15), pp. 2720-2727. Wiley-VCH 10.1002/elps.200800745
Mendoza-Ferri, Maria G.; Hartinger, Christian G.; Mendoza, Marco A.; Grössl, Michael; Egger, Alexander E.; Eichinger, Rene E.; Mangrum, John B.; Farrell, Nicholas P.; Maruszak, Magdalena; Bednarski, Patrick J.; Klein, Franz; Jakupec, Michael A.; Nazarov, Alexey A.; Severin, Kay; Keppler, Bernhard K. (2009). Transferring the Concept of Multinuclearity to Ruthenium Complexes for Improvement of Anticancer Activity. Journal of medicinal chemistry, 52(4), pp. 916-925. American Chemical Society 10.1021/jm8013234
Biba, Florian; Grössl, Michael; Egger, Alexander; Jakupec, Michael A.; Keppler, Bernhard K. (2009). A Novel Cytotoxic Cerium Complex: Aquatrichloridobis(1,10-phenanthroline)cerium(III) (KP776). Synthesis, Characterization, Behavior in H2O, Binding towards Biomolecules, and Antiproliferative Activity. Chemistry & Biodiversity, 6(12), pp. 2153-2165. Verlag Helvetica Chimica Acta 10.1002/cbdv.200900011
Hartinger, Christian G.; Jakupec, Michael A.; Zorbas-Seifried, Stefanie; Grössl, Michael; Egger, Alexander; Berger, Walter; Zorbas, Haralabos; Dyson, Paul J.; Keppler, Bernhard K. (2008). KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients. Chemistry & Biodiversity, 5(10), pp. 2140-2155. Verlag Helvetica Chimica Acta 10.1002/cbdv.200890195
Berger, Isabella; Hanif, Muhammad; Nazarov, Alexey A.; Hartinger, Christian G.; John, Roland O.; Kuznetsov, Maxim L.; Grössl, Michael; Schmitt, Frederic; Zava, Olivier; Biba, Florian; Arion, Vladimir B.; Galanski, Markus; Jakupec, Michael A.; Juillerat-Jeanneret, Lucienne; Dyson, Paul J.; Keppler, Bernhard K. (2008). In Vitro Anticancer Activity and Biologically Relevant Metabolization of Organometallic Ruthenium Complexes with Carbohydrate-Based Ligands. Chemistry - a European journal, 14(29), pp. 9046-9057. Wiley-VCH 10.1002/chem.200801032
Grössl, Michael; Hartinger, Christian G.; Połeć-Pawlak, Kasia; Jarosz, Maciej; Dyson, Paul J.; Keppler, Bernhard K. (2008). Elucidation of the Interactions of an Anticancer Ruthenium Complex in Clinical Trials with Biomolecules Utilizing Capillary Electrophoresis Hyphenated to Inductively Coupled Plasma-Mass Spectrometry. Short Communication. Chemistry & Biodiversity, 5(8), pp. 1609-1614. Verlag Helvetica Chimica Acta 10.1002/cbdv.200890148
Grössl, Michael; Hartinger, Christian G.; Polec-Pawlak, Kasia; Jarosz, Maciej; Keppler, Bernhard K. (2008). Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: A novel approach for the analysis of anticancer metallodrugs in human serum and plasma. Electrophoresis, 29(13), p. 2927. Wiley-VCH 10.1002/elps.200890060
Grössl, Michael; Hartinger, Christian G.; Dyson, Paul J.; Keppler, Bernhard K. (2008). CZE–ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP. Journal of inorganic biochemistry, 102(5-6), pp. 1060-1065. Elsevier 10.1016/j.jinorgbio.2007.11.018
Grössl, Michael; Hartinger, Christian G.; Polec-Pawlak, Kasia; Jarosz, Maciej; Keppler, Bernhard K. (2008). Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: A novel approach for the analysis of anticancer metallodrugs in human serum and plasma. Electrophoresis, 29(10), pp. 2224-2232. Wiley-VCH 10.1002/elps.200780790
Kogelnig, Daniel; Stojanovic, Anja; Galanski, Markus; Grössl, Michael; Jirsa, Franz; Krachler, Regina; Keppler, Bernhard K. (2008). Greener synthesis of new ammonium ionic liquids and their potential as extracting agents. Tetrahedron letters, 49(17), pp. 2782-2785. Elsevier 10.1016/j.tetlet.2008.02.138
Grössl, Michael; Reisner, Erwin; Hartinger, Christian G.; Eichinger, Rene; Semenova, Olga; Timerbaev, Andrei R.; Jakupec, Michael A.; Arion, Vladimir B.; Keppler, Bernhard K. (2007). Structure−Activity Relationships for NAMI-A-type Complexes (HL)[ trans -RuCl 4 L( S -dmso)ruthenate(III)] (L = Imidazole, Indazole, 1,2,4-Triazole, 4-Amino-1,2,4-triazole, and 1-Methyl-1,2,4-triazole): Aquation, Redox Properties, Protein Binding, and Antiproliferative Activity. Journal of medicinal chemistry, 50(9), pp. 2185-2193. American Chemical Society 10.1021/jm061081y
Berger, Isabella; Nazarov, Alexey A.; Hartinger, Christian G.; Grössl, Michael; Valiahdi, Seied-M.; Jakupec, Michael A.; Keppler, Bernhard K. (2007). A glucose derivative as natural alternative to the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin? ChemMedChem, 2(4), pp. 505-514. Wiley-VCH 10.1002/cmdc.200600279
Calvo, Daniel; Grössl, Michael; Cortina, Montserrat; del Valle, Manuel (2007). Automated SIA System Using an Array of Potentiometric Sensors for Determining Alkaline-Earth Ions in Water. Electroanalysis, 19(6), pp. 644-651. Wiley-VCH 10.1002/elan.200603763
Zorbas-Seifried, S.; Jakupec, M. A.; Kukushkin, N. V.; Grössl, Michael; Hartinger, C. G.; Semenova, O.; Zorbas, H.; Kukushkin, V. Yu.; Keppler, B. K. (2007). Reversion of Structure-Activity Relationships of Antitumor Platinum Complexes by Acetoxime but Not Hydroxylamine Ligands. Molecular pharmacology, 71(1), pp. 357-365. American Society for Pharmacology and Experimental Therapeutics 10.1124/mol.106.030726
Hartinger, C.G.; Hann, S.; Koellensperger, G.; Sulyok, M.; Grössl, Michael; Timerbaev, A.R.; Rudnev, A.V.; Stingeder, G.; Keppler, B.K. (2005). Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins ? significance for the patient. International journal of clinical pharmacology and therapeutics, 43(12), pp. 583-585. Dustri-Verlag 10.5414/CPP43583
