Karamitopoulou Diamantis, Evanthia

Karamitopoulou, Eva; Wenning, Anna Silvia; Acharjee, Animesh; Aeschbacher, Pauline; Marinoni, Ilaria; Zlobec, Inti; Gloor, Beat; Perren, Aurel (2024). Spatial heterogeneity of immune regulators drives dynamic changes of local immune responses, affecting disease outcomes in pancreatic cancer. (In Press). Clinical cancer research American Association for Cancer Research 10.1158/1078-0432.CCR-24-0368

Karamitopoulou, Eva (2023). Emerging prognostic and predictive factors in pancreatic cancer. Modern pathology, 36(11), p. 100328. Elsevier 10.1016/j.modpat.2023.100328

Karamitopoulou, Eva; Wenning, Anna Silvia; Acharjee, Animesh; Zlobec, Inti; Aeschbacher, Pauline; Perren, Aurel; Gloor, Beat (2023). Spatially restricted tumour-associated and host-associated immune drivers correlate with the recurrence sites of pancreatic cancer. Gut, 72(8), pp. 1523-1533. BMJ Publishing Group 10.1136/gutjnl-2022-329371

Ahmed, Asma; Reinhold, Cindy; Breunig, Eileen; Phan, Truong San; Dietrich, Lea; Kostadinova, Feodora; Urwyler, Corinne; Merk, Verena M; Noti, Mario; Toja da Silva, Israel; Bode, Konstantin; Nahle, Fatima; Plazzo, Anna Pia; Koerner, Julia; Stuber, Regula; Menche, Constantin; Karamitopoulou, Evanthia; Farin, Henner F; Gollob, Kenneth J and Brunner, Thomas (2023). Immune escape of colorectal tumors via local LRH-1/Cyp11b1-mediated synthesis of immunosuppressive glucocorticoids. Molecular oncology, 17(8), pp. 1545-1566. FEBS Press 10.1002/1878-0261.13414

Ferguson, L Paige; Gatchalian, Jovylyn; McDermott, Matthew L; Nakamura, Mari; Chambers, Kendall; Rajbhandari, Nirakar; Lytle, Nikki K; Rosenthal, Sara Brin; Hamilton, Michael; Albini, Sonia; Wartenberg, Martin; Zlobec, Inti; Galván Hernández, José Alberto; Karamitopoulou, Eva; Vavinskaya, Vera; Wascher, Alexis; Lowy, Andrew M; Schürch, Christian M; Puri, Pier Lorenzo; Bruneau, Benoit G; ... (2023). Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma. Nature Communications, 14(1), p. 292. Springer Nature 10.1038/s41467-023-35796-7

Zeng, Qiqun; Saghafinia, Sadegh; Chryplewicz, Agnieszka; Fournier, Nadine; Christe, Lucine; Xie, Yu-Qing; Guillot, Jeremy; Yucel, Simge; Li, Pumin; Galván, José A; Karamitopoulou, Eva; Zlobec, Inti; Ataca, Dalya; Gallean, Fleuriane; Zhang, Peng; Rodríguez-Calero, José Antonio; Rubin, Mark; Tichet, Mélanie; Homicsko, Krisztian and Hanahan, Douglas (2022). Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion. Science, 378(6621), eabl7207. American Association for the Advancement of Science 10.1126/science.abl7207

Wartenberg, Martin; Karamitopoulou-Diamantis, Eva (2022). Intraductal Papillary Mucinous Neoplasm (IPMN) and IPMN with Associated Invasive component. In: Esposito, Irene; Karamitopoulou-Diamantis, Eva (eds.) Pathology of the Pancreas. Encyclopedia of Pathology (pp. 98-105). Springer 10.1007/978-3-030-62416-3_5539

Wartenberg, Martin; Karamitopoulou-Diamantis, Eva (2022). Mucinous Cystic Neoplasm (MCN) and MCN with Associated Invasive Component. In: Esposito, Irene; Karamitopoulou-Diamantis, Eva (eds.) Pathology of the Pancreas. Encyclopedia of Pathology (pp. 140-144). Springer 10.1007/978-3-030-62416-3_5541

Wartenberg, Martin; Karamitopoulou-Diamantis, Eva (2022). Pancreatic Intraepithelial Neoplasia (PanIN). In: Esposito, Irene; Karamitopoulou-Diamantis, Eva (eds.) Pathology of the Pancreas. Encyclopedia of Pathology (pp. 168-171). Springer 10.1007/978-3-030-62416-3_5549

Wartenberg, Martin; Karamitopoulou-Diamantis, Eva (2022). Histology of the Pancreas. In: Esposito, Irene; Karamitopoulou-Diamantis, Eva (eds.) Pathology of the Pancreas. Encyclopedia of Pathology (pp. 92-94). Springer 10.1007/978-3-030-62416-3_5535

Karamitopoulou, Eva; Andreou, Andreas; Wenning, Anna Silvia; Gloor, Beat; Perren, Aurel (2022). High tumor mutational burden (TMB) identifies a microsatellite stable pancreatic cancer subset with prolonged survival and strong anti-tumor immunity. European journal of cancer, 169, pp. 64-73. Elsevier 10.1016/j.ejca.2022.03.033

Karamitopoulou, Eva (2022). Molecular Pathology of Pancreatic Cancer. Cancers, 14(6) MDPI AG 10.3390/cancers14061523

Carrasco-Garcia, Estefania; Lopez, Lidia; Moncho-Amor, Veronica; Carazo, Fernando; Aldaz, Paula; Collado, Manuel; Bell, Donald; Gaafar, Ayman; Karamitopoulou, Eva; Tzankov, Alexandar; Hidalgo, Manuel; Rubio, Ángel; Serrano, Manuel; Lawrie, Charles H; Lovell-Badge, Robin; Matheu, Ander (2022). SOX9 Triggers Different Epithelial to Mesenchymal Transition States to Promote Pancreatic Cancer Progression. Cancers, 14(4) MDPI AG 10.3390/cancers14040916

Karamitopoulou, Evanthia; Esposito, Irene; Zlobec, Inti; Insilla, Andrea Cacciato; Wartenberg, Martin; Schaeffer, David F; Kalloger, Steve; La Rosa, Stefano; Sempoux, Christine; Ramos Centeno, Irene; Lohneis, Philipp (2021). Reproducibility of tumor budding assessment in pancreatic cancer based on a multicenter interobserver study. Virchows Archiv, 478(4), pp. 719-726. Springer 10.1007/s00428-020-02987-2

Sadozai, Hassan; Acharjee, Animesh; Gruber, Thomas; Gloor, Beat; Karamitopoulou, Eva (2021). Pancreatic Cancers with High Grade Tumor Budding Exhibit Hallmarks of Diminished Anti-Tumor Immunity. Cancers, 13(5) MDPI AG 10.3390/cancers13051090

Sadozai, Hassan; Acharjee, Animesh; Eppenberger-Castori, Serenella; Gloor, Beat; Gruber, Thomas; Schenk, Mirjam; Karamitopoulou Diamantis, Evanthia (2021). Distinct Stromal and Immune Features Collectively Contribute to Long-Term Survival in Pancreatic Cancer. Frontiers in immunology, 12(643529), p. 643529. Frontiers Research Foundation 10.3389/fimmu.2021.643529

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Karamitopoulou, Evanthia; Gloor, Beat (2019). Clinical Scenarios Emerging from Combined Immunophenotypic, Molecular and Morphologic Analysis of Pancreatic Cancer: The Good, the Bad and the Ugly Scenario. Cancers, 11(7) MDPI AG 10.3390/cancers11070968

Lytle, Nikki K.; Ferguson, L. Paige; Rajbhandari, Nirakar; Gilroy, Kathryn; Fox, Raymond G.; Deshpande, Anagha; Schürch, Christian M.; Hamilton, Michael; Robertson, Neil; Lin, Wei; Noel, Pawan; Wartenberg, Martin; Zlobec, Inti; Eichmann, Micha David; Galván, José A.; Karamitopoulou, Evanthia; Gilderman, Tami; Esparza, Lourdes Adriana; Shima, Yutaka; Spahn, Philipp; ... (2019). A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Cell, 177(3), 572-586.e22. Cell Press 10.1016/j.cell.2019.03.010

Wartenberg, Martin; Cibin, Silvia; Zlobec, Inti; Vassella, Erik; Eppenberger-Castori, Serenella; Terracciano, Luigi; Eichmann, Micha David; Worni, Mathias; Gloor, Beat; Perren, Aurel; Karamitopoulou, Evanthia (2018). Integrated Genomic and Immunophenotypic Classification of Pancreatic Cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance. Clinical cancer research, 24(18), pp. 4444-4454. American Association for Cancer Research 10.1158/1078-0432.CCR-17-3401

Karamitopoulou, Evanthia; Wartenberg, Martin; Zlobec, Inti; Cibin, Silvia; Worni, Mathias; Gloor, Beat; Lugli, Alessandro (2018). Tumour budding in pancreatic cancer revisited: validation of the ITBCC scoring system. Histopathology, 73(1), pp. 137-146. Wiley 10.1111/his.13508

Li, Leanne; Zeng, Qiqun; Bhutkar, Arjun; Galván Hernández, José Alberto; Karamitopoulou, Evanthia; Noordermeer, Daan; Peng, Mei-Wen; Piersigilli, Alessandra; Perren, Aurel; Zlobec, Inti; Robinson, Hugh; Iruela-Arispe, M. Luisa; Hanahan, Douglas (2018). GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth. Cancer cell, 33(4), 736-751.e5. Cell Press 10.1016/j.ccell.2018.02.011

Mager, Lukas Franz; Kölzer, Viktor Hendrik; Stuber Roos, Regula; Thoo Sin Lang, Lester; Keller, Irene; Köck, Ivonne; Langenegger, Maya; Simillion, Cedric; Pfister, Simona P; Faderl, Martin Richard; Genitsch Gratwohl, Vera; Tcymbarevich, Irina; Juillerat, Pascal; Li, Xiaohong; Xia, Yu; Karamitopoulou, Evanthia; Lyck, Ruth; Zlobec, Inti; Hapfelmeier, Siegfried Hektor; Bruggmann, Rémy; ... (2017). The ESRP1-GPR137 axis contributes to intestinal pathogenesis. eLife, 6 eLife Sciences Publications 10.7554/eLife.28366

Karamitopoulou, Evanthia; Haemmig, Stefan; Baumgartner, Ulrich; Schlup, Cornelia; Wartenberg, Martin; Vassella, Erik (2017). MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. Modern pathology, 30(8), pp. 1116-1125. Nature Publishing Group 10.1038/modpathol.2017.35

Ivanovska, Jelena; Zlobec, Inti; Forster, Stefan; Karamitopoulou, Evanthia; Dawson, Heather; Koelzer, Viktor Hendrik; Agaimy, Abbas; Garreis, Fabian; Söder, Stephan; Laqua, William; Lugli, Alessandro; Hartmann, Arndt; Rau, Tilman; Schneider-Stock, Regine (2017). Correction: DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells. OncoTarget, 8(11), pp. 18615-18616. Impact Journals LLC 10.18632/oncotarget.16154

Jakob, Dominik; Worni, Mathias; Karamitopoulou, Evanthia; Gloor, Beat (2017). Undifferenziertes Pankreaskarzinom- fulminanter Verlauf (Unpublished). In: Schweizerische Gesellschaft für Chirurgie Kongress 2017. Bern.

Wartenberg, Martin; Centeno, Irene; Haemmig, Stefan; Vassella, Erik; Zlobec, Inti; Galván, José A.; Neuenschwander, Maja; Schlup, Cornelia; Gloor, Beat; Lugli, Alessandro; Perren, Aurel; Karamitopoulou, Evanthia (2016). PTEN alterations of the stromal cells characterise an aggressive subpopulation of pancreatic cancer with enhanced metastatic potential. European journal of cancer, 65, pp. 80-90. Elsevier 10.1016/j.ejca.2016.06.013

Kölzer, Viktor; Canonica, Katharina; Dawson, Heather; Sokol, Lena; Karamitopoulou, Evanthia; Lugli, Alessandro; Zlobec, Inti (2016). Phenotyping of tumor-associated macrophages in colorectal cancer: Impact on single cell invasion (tumor budding) and clinicopathological outcome. Oncoimmunology, 5(4), e1106677. Taylor & Francis 10.1080/2162402X.2015.1106677

Ivanovska, Jelena; Zlobec, Inti; Forster, Stefan; Karamitopoulou, Evanthia; Dawson, Heather; Kölzer, Viktor; Agaimy, Abbas; Garreis, Fabian; Söder, Stephan; Laqua, William; Lugli, Alessandro; Hartmann, Arndt; Rau, Tilman; Schneider-Stock, Regine (2015). DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells. OncoTarget, 6(34), pp. 36774-36788. Impact Journals LLC 10.18632/oncotarget.4908

Kölzer, Viktor; Huber, Bettina; Mele, Valentina; Iezzi, Giandomenica; Trippel, Mafalda; Karamitopoulou, Evanthia; Zlobec, Inti; Lugli, Alessandro (2015). Expression of the hyaluronan-mediated motility receptor RHAMM in tumor budding cells identifies aggressive colorectal cancers. Human pathology, 46(11), pp. 1573-1581. Elsevier 10.1016/j.humpath.2015.07.010

Galván Hernández, José Alberto; Zlobec, Inti; Wartenberg, Martin; Lugli, Alessandro; Gloor, Beat; Perren, Aurel; Karamitopoulou, Evanthia (2015). Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer. British journal of cancer, 112(12), pp. 1944-1950. Nature Publishing Group 10.1038/bjc.2015.177

Kölzer, Viktor; Dawson, Heather; Andersson, Emilia; Karamitopoulou, Evanthia; Masucci, Giuseppe V; Lugli, Alessandro; Zlobec, Inti (2015). Active immunosurveillance in the tumor microenvironment of colorectal cancer is associated with low frequency tumor budding and improved outcome. Translational Research, 166(2), pp. 207-217. Elsevier 10.1016/j.trsl.2015.02.008

Wartenberg, Martin; Zlobec, Inti; Perren, Aurel; Kölzer, Viktor; Gloor, Beat; Lugli, Alessandro; Karamitopoulou, Evanthia (2015). Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma. OncoTarget, 6(6), pp. 4190-4201. Impact Journals LLC

Karamitopoulou, Evanthia; Zlobec, Inti; Kölzer, Viktor; Langer, Rupert; Dawson, Heather; Lugli, Alessandro (2015). Tumour border configuration in colorectal cancer: proposal for an alternative scoring system based on the percentage of infiltrating margin. Histopathology, 67(4), pp. 464-473. Blackwell Scientific Publications 10.1111/his.12665

Vidal, A D; Thalmann, George; Karamitopoulou, Evanthia; Fey, Martin; Studer, Urs (2015). Long-term outcome of patients with clinical stage I high-risk nonseminomatous germ-cell tumors 15 years after one adjuvant cycle of bleomycin, etoposide, and cisplatin chemotherapy. Annals of oncology, 26(2), pp. 374-377. Oxford University Press 10.1093/annonc/mdu518

Galván Hernández, José Alberto; Helbling, Melina; Kölzer, Viktor; Tschan, Mario; Berger, Martin Dave; Hädrich, Marion; Schnüriger, Beat; Karamitopoulou, Evanthia; Dawson, Heather; Inderbitzin, Daniel; Lugli, Alessandro; Zlobec, Inti (2015). TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer. OncoTarget, 6(2), pp. 874-885. Impact Journals LLC 10.18632/oncotarget.2716

Kölzer, Viktor; Herrmann, Pia; Zlobec, Inti; Karamitopoulou, Evanthia; Lugli, Alessandro; Stein, Ulrike (2015). Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study. BMC cancer, 15(160), p. 160. BioMed Central 10.1186/s12885-015-1150-z

Sokol, Lena; Kölzer, Viktor; Rau, Tilman; Karamitopoulou, Evanthia; Zlobec, Inti; Lugli, Alessandro (2015). Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer. Journal of translational medicine, 13(279), p. 279. BioMed Central 10.1186/s12967-015-0647-1

Nisa Hernandez, Lluis; Landis, Basile Nicolas; Salmina, Cinzia; Ailianou, Angeliki; Karamitopoulou, Evanthia; Giger, Roland (2015). Warthin's tumor of the larynx: a very rare case and systematic review of the literature. Journal of Otolaryngology - Head and Neck Surgery, 44(16), p. 16. BioMed Central 10.1186/s40463-015-0067-5

Dawson, Heather; Grundmann, Sandra; Kölzer, Viktor; Galván Hernández, José Alberto; Kirsch, Richard; Karamitopoulou, Evanthia; Lugli, Alessandro; Inderbitzin, Daniel; Zlobec, Inti (2014). Tyrosine kinase receptor B (TrkB) expression in colorectal cancers highlights anoikis resistance as a survival mechanism of tumour budding cells. Histopathology, 66(5), pp. 715-725. Blackwell Scientific Publications 10.1111/his.12603

Karamitopoulou, Evanthia; Thies, Svenja; Zlobec, Inti; Ott, Katja; Feith, Marcus; Slotta-Huspenina, Julia; Lordick, Florian; Becker, Karen; Langer, Rupert (2014). Assessment of tumor regression of esophageal adenocarcinomas after neoadjuvant chemotherapy: comparison of 2 commonly used scoring approaches. The American journal of surgical pathology, 38(11), pp. 1551-1556. Lippincott Williams & Wilkins 10.1097/PAS.0000000000000255

Waser, Beatrice; Blank, Annika; Karamitopoulou, Evanthia; Perren, Aurel; Reubi, Jean-Claude (2014). Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas. Modern pathology, 28(3), pp. 391-402. Nature Publishing Group 10.1038/modpathol.2014.113

Helbling, Melina; Lukesch, Anne Carolin; Haimovici, Aladin; Karamitopoulou, Evanthia; Berger, Martin Dave; Hädrich, Marion; Mallaev, Makhmud; Schnüriger, Beat; Kölzer, Viktor; Dawson, Heather; Borner, Markus; Langer, Rupert; Rosenberg, Robert; Nitsche, Ulrich; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2014). Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients. OncoTarget, 5(13), pp. 4671-4682. Impact Journals LLC

Kalimeris, K.; Zerva, A.; Matsota, P.; Nomikos, T.; Fragopoulou, E.; Politi, A.; Karamitopoulou, E.; Kostopanagiotou, G. (2014). Pre-treatment with sevoflurane attenuates direct lung injury. Minerva anestesiologica, 80(6), pp. 635-644. Minerva Medica

Dawson, Heather; Galván Hernández, José Alberto; Helbling, Melina; Müller, Dominique-Elisabeth; Karamitopoulou, Evanthia; Kölzer, Viktor; Economou, Mary; Hammer, Caroline; Lugli, Alessandro; Zlobec, Inti (2014). Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency. International journal of cancer, 134(10), pp. 2342-2351. Wiley-Blackwell 10.1002/ijc.28564

Dawson, Heather; Kölzer, Viktor; Karamitopoulou, Evanthia; Economou, Mary; Hammer, Caroline; Müller, Dominique-Elisabeth; Lugli, Alessandro; Zlobec, Inti (2014). The apoptotic and proliferation rate of tumour budding cells in colorectal cancer outlines a heterogeneous population of cells with various impacts on clinical outcome. Histopathology, 64(4), pp. 577-584. Blackwell Scientific Publications 10.1111/his.12294

Dawson, Heather; Kölzer, Viktor; Karamitopoulou, Evanthia; Lugli, Alessandro; Zlobec, Inti (February 2014). Loss of Cdx2 Is a Potential Marker of the Serrated Pathway of Colorectal Cancer Characterized by BRAF Mutation, High-Level CpG Island Methylator Phenotype and Mismatch Repair-Deficiency. Modern pathology, 27, 171A-171A. Nature Publishing Group

Dawson, Heather; Kölzer, Viktor; Karamitopoulou, Evanthia; Lugli, Alessandro; Zlobec, Inti (February 2014). Loss of Cdx2 Is a Potential Marker of the Serrated Pathway of Colorectal Cancer Characterized by BRAF Mutation, High-Level CpG Island Methylator Phenotype and Mismatch Repair-Deficiency. Laboratory investigation, 94, 171A-171A. Nature Publishing Group

Sconocchia, Giuseppe; Eppenberger-Castori, Serenella; Zlobec, Inti; Karamitopoulou, Evanthia; Arriga, Roberto; Coppola, Andrea; Caratelli, Sara; Spagnoli, Giulio Cesare; Lauro, Davide; Lugli, Alessandro; Han, Junyi; Iezzi, Giandomenica; Ferrone, Cristina; Ferlosio, Amedeo; Tornillo, Luigi; Droeser, Raoul; Rossi, Piero; Attanasio, Antonio; Ferrone, Soldano and Terracciano, Luigi (2014). HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker. Neoplasia, 16(1), pp. 31-42. Nature America 10.1593/neo.131568

Karamitopoulou, Evanthia; Shoni, M; Theoharides, T C (2014). Increased number of non-degranulated mast cells in pancreatic ductal adenocarcinoma but not in acute pancreatitis. International journal of immunopathology and pharmacology, 27(2), pp. 213-220. Biomedical Research Press

Baker, Kristi; Rath, Timo; Flak, Magdalena B.; Arthur, Janelle C.; Chen, Zhangguo; Glickman, Jonathan N.; Zlobec, Inti; Karamitopoulou, Evanthia; Stachler, Matthew D.; Odze, Robert D.; Lencer, Wayne I.; Jobin, Christian; Blumberg, Richard S. (2013). Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer. Immunity, 39(6), pp. 1095-1107. Cell Press 10.1016/j.immuni.2013.11.003

Dawson, Heather; André, Sabine; Karamitopoulou, Evanthia; Zlobec, Inti; Gabius, Hans-Joachim (2013). The growing galectin network in colon cancer and clinical relevance of cytoplasmic galectin-3 reactivity. Anticancer research, 33(8), pp. 3053-3059. International Inst. of Anticancer Research

Karamitopoulou, Eva; Gloor, B. (2013). Tumour budding is a strong and independent prognostic factor in pancreatic cancer. Reply to comment. European journal of cancer, 49(10), pp. 2458-2459. Elsevier 10.1016/j.ejca.2013.03.028

Kölzer, V.; Karamitopoulou, E.; Dawson, Heather; Kondi-Pafiti, A.; Zlobec, I.; Lugli, A. (2013). Geographic analysis of RKIP expression and its clinical relevance in colorectal cancer. British journal of cancer, 108(10), pp. 2088-2096. Nature Publishing Group 10.1038/bjc.2013.197

Karamitopoulou, Evanthia; Zlobec, I; Born, D; Kondi-Pafiti, A; Lykoudis, P; Mellou, A; Gennatas, K; Gloor, B; Lugli, A (2013). Tumour budding is a strong and independent prognostic factor in pancreatic cancer. European journal of cancer, 49(5), pp. 1032-9. Amsterdam: Elsevier 10.1016/j.ejca.2012.10.022

Karamitopoulou, Evanthia; Zlobec, Inti; Kölzer, Viktor; Kondi-Pafiti, Agathi; Patsouris, Efstratios S; Gennatas, Konstantin; Lugli, Alessandro (2013). Proposal for a 10-high-power-fields scoring method for the assessment of tumor budding in colorectal cancer. Modern pathology, 26(2), pp. 295-301. London: Nature Publishing Group 10.1038/modpathol.2012.155

Karamitopoulou, Evanthia; Zlobec, Inti; Gloor, Beat; Kondi-Pafiti, Agathi; Lugli, Alessandro; Perren, Aurel (2013). Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC). Journal of translational medicine, 11, p. 311. BioMed Central 10.1186/1479-5876-11-311

Dawson, Heather; Zlobec, Inti; Kölzer, Viktor; Karamitopoulou, Evanthia; Lugli, Alessandro (2013). Expression pattern of TrkB in colorectal cancer supports anoikis-resistance as a survival mechanism for tumor budding cells. Virchows Archiv, 463(2), p. 107. Springer

Karamitopoulou, Evanthia; Zlobec, Inti; Perren, Aurel; Gloor, Beat; Lugli, Alessandro (2013). Increased tumor-budding/CD8+lymphocytes ratio is associated with metastasis and venous invasion in Pancreatic Ductal Adenocarcinoma (PDAC). Virchows Archiv, 463(2), p. 106. Springer

Zlobec, Inti; Kölzer, Viktor; Dawson, Heather; Langer, Rupert; Karamitopoulou, Evanthia; Lugli, Alessandro (2013). Investigation of IL23 (p19, p40) and IL23R highlights nuclear IL23p19 expression as a marker of indolent tumor features and favorable outcome in colorectal cancer patients. Virchows Archiv, 463(2), pp. 139-140. Springer 10.1007/s00428-013-1444-y

Karamitopoulou, Evanthia; Zlobec, Inti; Gloor, Beat; Lugli, Alessandro; Perren, Aurel (2013). PTEN Loss in the Neoplastic Stroma of Pancreatic Ductal Adenocarcinoma (PDAC) Is a Strong Predictor of Distant Metastasis. Gastroenterology, 144(5) Elsevier

Zlobec, I.; Helbling, M.; Dawson, Heather; Kölzer, V. H.; Diamantis Karamitopoulou, E.; Lugli, A. (2013). Hypermethylation of ZEB2 represents a novel mechanism of colorectal cancer progression and is a highly unfavourable prognostic factor in KRAS wild-type tumors. Virchows Archiv, 463(2), p. 139. Springer

Karamitopoulou, E.; Zlobec, I.; Gloor, B.; Lugli, A.; Kölzer, V. (2013). Loss of PTEN expression in tumor microenvironment correlates with aggressive behaviour and detects synergistic roles of tumor and stromal cells in Pancreatic Ductal Adenocarcinoma (PDAC). Virchows Archiv, 463(2), pp. 290-291. Springer

Kölzer, V. H.; Dawson, Heather; Karamitopoulou, E.; Lugli, A.; Zlobec, I. (2013). Loss of RKIP Expression in Colorectal Cancer Is Associated with Activation of the NF-kappa B Signaling Pathway and Epithelial-Mesenchymal Transition. Laboratory investigation, 93(S1), 161A-161A. Nature Publishing Group

Kölzer, V. H.; Dawson, Heather; Karamitopoulou, E.; Lugli, A.; Zlobec, I. (2013). Loss of RKIP Expression in Colorectal Cancer Is Associated with Activation of the NF-kappa B Signaling Pathway and Epithelial-Mesenchymal Transition. Modern pathology, 26(S2), 161A-161A. Nature Publishing Group 10.1038/modpathol.2013.9

Zlobec, I.; Helbling, M.; Dawson, Heather; Kölzer, V. H.; Karamitopoulou, E.; Lugli, A. (2013). ZEB2 CpG promoter methylation in colorectal cancer is associated with lymph node metastases and invasion in KRAS wild-type patients. Pathologe, 34(6), p. 592. Springer-Medizin-Verlag

Diamantis-Karamitopoulou, E.; Lugli, A.; Gloor, B.; Perren, A.; Zlobec, I. (2013). Decreased CD8+ lymphocytes/tumor budding ratio is associated with metastasis and venous invasion in pancreatic ductal adenocarcinoma (PDAC). Pathologe, 34(6), p. 601. Springer-Medizin-Verlag

Dawson, Heather; Kölzer, Viktor; Karamitopoulou, Evanthia; Lugli, Alessandro; Zlobec, Inti (2013). TrkB expression in colorectal cancers highlights anoiks-resistance as a possible survival mechanism of tumor budding (EMT-like) cells. Pathologe, 34(6), pp. 602-603. Springer-Medizin-Verlag

Zlobec, I.; Helbling, M.; Karamitopoulou, E.; Dawson, Heather; Kölzer, V. H.; Lugli, A. (2013). CpG promoter hypermethylation of CTNNB1 (B-catenin) and TWIST2 promote a high-grade tumor budding phenotype in colorectal cancer. Pathologe, 34(6), p. 603. Springer-Medizin-Verlag

Kölzer, Viktor; Canonica, Katharina; Dawson, Heather; Karamitopoulou, Evanthia; Lugli, Alessandro; Zlobec, Inti (2013). Stromal macrophages closely interact with infiltrating tumor cells in the tumor microenvironemnt of colorectal cancer. Pathologe, 34(6), p. 604. Springer-Medizin-Verlag

Karamitopoulou, Evanthia (2013). Role of Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Is Tumor Budding the Missing Link? Frontiers in oncology, 3, p. 221. Frontiers Research Foundation 10.3389/fonc.2013.00221

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Karamitopoulou, Evanthia; Zlobec, Inti; Gloor, Beat; Kondi-Pafiti, A.; Lugli, Alessandro; Perren, Aurel (2013). Loss of Raf-1 Kinase Inhibitor Protein (RKIP) promotes Epithelial Mesenchymal Transition (EMT) and correlates with aggressive phenotype in Pancreatic Ductal Adenocarcinoma (PDAC). Virchows Archiv, 463(2), p. 139. Springer

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Horcic, Milo; Koelzer, Viktor H; Karamitopoulou, Eva; Terracciano, Luigi; Puppa, Giacomo; Zlobec, Inti; Lugli, Alessandro (2012). Tumor budding score based on 10 high-power fields is a promising basis for a standardized prognostic scoring system in stage II colorectal cancer. Human pathology, 44(5), pp. 697-705. Philadelphia, Pa.: Elsevier 10.1016/j.humpath.2012.07.026

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Piscuoglio, Salvatore; Zlobec, Inti; Pallante, Pierlorenzo; Sepe, Romina; Esposito, Francesco; Zimmermann, Arthur; Diamantis, Ioannis; Terracciano, Luigi; Fusco, Alfredo; Karamitopoulou, Eva (2012). HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma. Histopathology, 60(3), pp. 397-404. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2559.2011.04121.x

Tsapralis, Dimitrios; Panayiotides, Ioannis; Peros, George; Liakakos, Theodore; Karamitopoulou, Eva (2012). Human epidermal growth factor receptor-2 gene amplification in gastric cancer using tissue microarray technology. World journal of gastroenterology, 18(2), pp. 150-5. Beijing (China): WJG Press 10.3748/wjg.v18.i2.150

Papas, Maria G; Karatzas, Pantelis S; Papanikolaou, Ioannis S; Karamitopoulou, Evanthia; Delicha, Eumorphia M; Adler, Andreas; Triantafyllou, Konstantinos; Thomopoulou, Georgia-Heleni; Patsouris, Efstratios; Lazaris, Andreas C (2012). LFA-1 expression in a series of colorectal adenocarcinomas. Journal of gastrointestinal cancer, 43(3), pp. 462-6. New York, N.Y.: Springer 10.1007/s12029-011-9341-6

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