Fleischmann, Achim

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Journal Article

Frei, Ana Leni; Oberson, Raphaël; Baumann, Elias; Perren, Aurel; Grobholz, Rainer; Lugli, Alessandro; Dawson, Heather; Abbet, Christian; Lertxundi, Ibai; Reinhard, Stefan; Mookhoek, Aart; Feichtinger, Johann; Sarro, Rossella; Gadient, Gallus; Dommann-Scherrer, Corina; Barizzi, Jessica; Berezowska, Sabina; Glatz, Katharina; Dertinger, Susanne; Banz, Yara; ... (2023). Pathologist computer-aided diagnostic scoring of tumor cell fraction: A Swiss national study. Modern pathology, 36(12), p. 100335. Springer Nature 10.1016/j.modpat.2023.100335

Gallon, John; Rodríguez-Calero, Antonio; Benjak, Andrej; Akhoundova, Dilara; Maletti, Sina; Amstutz, Ursula; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; Bubendorf, Lukas; Moch, Holger; Thalmann, George; Feng, Felix Y; Gillessen, Silke; ... (2023). DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations. Cancer research, 83(8), pp. 1203-1213. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-22-2236

Özdemir, Berna C; Arnold, Nicolas; Fleischmann, Achim; Hensel, Janine; Klima, Irena; Kruithof-de Julio, Marianna; Burkhard, Fiona; Hayoz, Stefanie; Kiss, Bernhard; Thalmann, George N (2022). Prediction of Biochemical Recurrence Based on Molecular Detection of Lymph Node Metastasis After Radical Prostatectomy. European urology open science, 44, pp. 1-10. Elsevier 10.1016/j.euros.2022.07.005

Rodriguez-Calero, Antonio; Gallon, John; Akhoundova, Dilara; Maletti, Sina; Ferguson, Alison; Cyrta, Joanna; Amstutz, Ursula; Garofoli, Andrea; Paradiso, Viola; Tomlins, Scott A; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Vassella, Erik; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; ... (2022). Alterations in homologous recombination repair genes in prostate cancer brain metastases. Nature Communications, 13(1), p. 2400. Springer Nature 10.1038/s41467-022-30003-5

Moskovszky, Linda; Berger, Barbara; Fleischmann, Achim; Friedrich, Thomas; Helmchen, Birgit; Körner, Meike; Rau, Tilman T.; Varga, Zsuzsanna (2020). Inter-observer reproducibility of classical lobular neoplasia (B3 lesions) in preoperative breast biopsies: a study of the Swiss Working Group of breast and gynecopathologists. Journal of cancer research and clinical oncology, 146(6), pp. 1473-1478. Springer 10.1007/s00432-020-03195-w

Savic Prince, Spasenija; Berezowska, Sabina Anna; Eppenberger-Castori, Serenella; Cathomas, Gieri; Diebold, Joachim; Fleischmann, Achim; Jochum, Wolfram; Komminoth, Paul; McKee, Thomas; Letovanec, Igor; Jasarevic, Zerina; Rössle, Matthias; Singer, Gad; von Gunten, Michael; Zettl, Andreas; Zweifel, Roland; Soltermann, Alex; Bubendorf, Lukas (2019). PD-L1 testing of non-small cell lung cancer using different antibodies and platforms: a Swiss cross-validation study. Virchows Archiv, 475(1), pp. 67-76. Springer 10.1007/s00428-019-02582-0

Genitsch Gratwohl, Vera; Zlobec, Inti; Seiler, Roland; Thalmann, George; Fleischmann, Achim (2017). Neuroendocrine Differentiation in Metastatic Conventional Prostate Cancer Is Significantly Increased in Lymph Node Metastases Compared to the Primary Tumors. International journal of molecular sciences, 18(8) MDPI 10.3390/ijms18081640

Kiss, Bernhard; Wyatt, Alexander W; Douglas, James; Skuginna, Veronika Olga; Mo, Fan; Anderson, Shawn; Rotzer, Diana; Fleischmann, Achim; Genitsch Gratwohl, Vera; Hayashi, Tetsutaro; Neuenschwander, Maja; Buerki, Christine; Davicioni, Elai; Collins, Colin; Thalmann, George; Black, Peter C; Seiler, Roland (2017). Her2 alterations in muscle-invasive bladder cancer: Patient selection beyond protein expression for targeted therapy. Scientific Reports, 7(42713), p. 42713. Nature Publishing Group 10.1038/srep42713

Genitsch Gratwohl, Vera; Zlobec, Inti; Fleischmann, Achim; Thalmann, George (2016). MUC1 in lymph node metastases independently predicts survival in advanced prostate cancer patients. Prostate Cancer Prostatic Diseases, 19(3), pp. 242-247. Springer 10.1038/pcan.2016.11

Hassel, C.; Blaum, K.; Goodacre, T. Day; Dorrer, Holger Johann; Düllmann, Ch. E.; Eberhardt, K.; Eliseev, S.; Enss, C.; Filianin, P.; Fäßler, A.; Fleischmann, Achim; Gastaldo, L.; Goncharov, M.; Hengstler, D.; Jochum, J.; Johnston, K.; Keller, M.; Kempf, S.; Kieck, T.; Köster, U.; ... (2016). Recent Results for the ECHo Experiment. Journal of low temperature physics, 184(3-4), pp. 910-921. Springer 10.1007/s10909-016-1541-9

Ho, Melissa E; Quek, Sue-Ing; True, Lawrence D; Seiler, Roland; Fleischmann, Achim; Bagryanova, Lora; Kim, Sara R; Chia, David; Goodglick, Lee; Shimizu, Yoshiko; Rosser, Charles J; Gao, Yuqian; Liu, Alvin Y (2016). Bladder cancer cells secrete while normal bladder cells express but do not secrete AGR2. OncoTarget, 7(13), pp. 15747-15756. Impact Journals LLC 10.18632/oncotarget.7400

Tschui, Joëlle; Vassella, Erik; Bandi Hess, Nora; Baumgartner, Ulrich; Genitsch Gratwohl, Vera; Rotzer, Diana; Seiler, Roland; Thalmann, George; Fleischmann, Achim (2015). Morphological and molecular characteristics of HER2 amplified urothelial bladder cancer. Virchows Archiv, 466(6), pp. 703-710. Springer 10.1007/s00428-015-1729-4

Kiss, Bernhard; Skuginna, Veronika; Fleischmann, Achim; Bell, Robert H; Collins, Colin; Thalmann, George; Seiler, Roland (2015). Bcl-2 predicts response to neoadjuvant chemotherapy and is overexpressed in lymph node metastases of urothelial cancer of the bladder. Urologic oncology - seminars and original investigations, 33(4), 166.e1-166.e8. Elsevier 10.1016/j.urolonc.2014.12.005

Turo, Rafal; Harnden, Patricia; Thygesen, Helene; Fleischmann, Achim; Thalmann, George; Seiler, Roland; Cross, William R; Knowles, Margaret A (2015). FGFR3 expression in primary invasive bladder cancers and matched lymph node metastases. Journal of urology, 193(1), pp. 325-330. Elsevier 10.1016/j.juro.2014.06.026

Fleischmann, Achim; Saramäki, Outi R; Zlobec, Inti; Rotzer, Diana; Genitsch Gratwohl, Vera; Seiler, Roland; Visakorpi, Tapio; Thalmann, George (2014). Prevalence and prognostic significance of TMPRSS2-ERG gene fusion in lymph node positive prostate cancers. Prostate, 74(16), pp. 1647-1654. Wiley-Blackwell 10.1002/pros.22882

Thöny, Harriet C.; Froehlich, Johannes M; Triantafyllou, Maria; Huesler, Juerg; Bains, Lauren; Vermathen, Peter; Fleischmann, Achim; Studer, Urs (2014). Metastases in normal-sized pelvic lymph nodes: detection with diffusion-weighted MR imaging. Radiology, 273(1), pp. 125-135. Radiological Society of North America RSNA 10.1148/radiol.14132921

Bains, Lauren; Studer, Urs; Froehlich, Johannes M; Giannarini, Gianluca; Triantafyllou, Maria; Fleischmann, Achim; Thöny, Harriet C. (2014). Diffusion-weighted magnetic resonance imaging detects significant prostate cancer with high probability. Journal of urology, 192(3), pp. 737-742. Elsevier 10.1016/j.juro.2014.03.039

Fleischmann, Achim; Thalmann, George; Perren, Aurel; Seiler, Roland (2014). Tumor regression grade of urothelial bladder cancer after neoadjuvant chemotherapy: a novel and successful strategy to predict survival. The American journal of surgical pathology, 38(3), pp. 325-332. Lippincott Williams & Wilkins 10.1097/PAS.0000000000000142

Seiler, Roland; Thalmann, George N.; Rotzer, Diana; Perren, Aurel; Fleischmann, Achim (2014). CCND1/CyclinD1 status in metastasizing bladder cancer: a prognosticator and predictor of chemotherapeutic response. Modern pathology, 27(1), pp. 87-95. Nature Publishing Group 10.1038/modpathol.2013.125

Oezdemir, Berna; Hensel, Janine; Secondini, Chiara; Wetterwald, Antoinette; Schwaninger, Ruth; Fleischmann, Achim; Raffelsberger, Wolfgang; Poch, Olivier; Delorenzi, Mauro; Temanni, Ramzi; Mills, Ian G; van der Pluijm, Gabri; Thalmann, George; Cecchini, Marco Giovanni (2014). The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches. PLoS ONE, 9(12), e114530. Public Library of Science 10.1371/journal.pone.0114530

Mansi, Rosalba; Fleischmann, Achim; Mäcke, Helmut R.; Reubi, Jean-Claude (2013). Targeting GRPR in urological cancers--from basic research to clinical application. Nature Reviews. Urology, 10(4), pp. 235-244. Nature Publishing Group 10.1038/nrurol.2013.42

Triantafyllou, Maria; Studer, Urs E.; Birkhäuser, Frédéric D.; Fleischmann, Achim; Bains, Lauren J.; Petralia, Giuseppe; Christe, Andreas; Fröhlich, Johannes M.; Thoeny, Harriet C. (2013). Ultrasmall superparamagnetic particles of iron oxide allow for the detection of metastases in normal sized pelvic lymph nodes of patients with bladder and/or prostate cancer. European journal of cancer, 49(3), pp. 616-624. Amsterdam: Elsevier 10.1016/j.ejca.2012.09.034

Birkhäuser, Frédéric D.; Studer, Urs E.; Froehlich, Johannes M.; Triantafyllou, Maria; Bains, Lauren J.; Petralia, Giuseppe; Vermathen, Peter; Fleischmann, Achim; Thoeny, Harriet C. (2013). Combined Ultrasmall Superparamagnetic Particles of Iron Oxide–Enhanced and Diffusion-weighted Magnetic Resonance Imaging Facilitates Detection of Metastases in Normal-sized Pelvic Lymph Nodes of Patients with Bladder and Prostate Cancer. European urology, 64(6), pp. 953-960. Elsevier 10.1016/j.eururo.2013.07.032

Seiler, Roland; von Gunten, Michael; Thalmann, George N; Fleischmann, Achim (2012). High CD10 expression predicts favorable outcome in surgically treated lymph node-positive bladder cancer patients. Human pathology, 43(2), pp. 269-75. Philadelphia, Pa.: Elsevier 10.1016/j.humpath.2011.04.030

Froehlich, Johannes M; Triantafyllou, Maria; Fleischmann, Achim; Vermathen, Peter; Thalmann, George N; Thoeny, Harriet C (2012). Does quantification of USPIO uptake-related signal loss allow differentiation of benign and malignant normal-sized pelvic lymph nodes? Contrast media & molecular imaging, 7(3), pp. 346-55. Chichester: Wiley 10.1002/cmmi.503

Matter, Alexandra; Hewer, Ekkehard; Kappeler, Andreas; Fleischmann, Achim; Vajtai, Istvan (2012). Plexiform hybrid granular cell tumor/perineurioma: a novel variant of benign peripheral nerve sheath tumor with divergent differentiation. Pathology, research and practice, 208(5), pp. 310-4. München: Elsevier 10.1016/j.prp.2012.02.014

Kiss, Bernhard; Birkhäuser, Frédéric D.; Fleischmann, Achim; Candinas, Daniel; Studer, Urs E.; Kessler, Thomas M. (2011). Refractory Hematuria in an Oliguric Patient After Pancreas Transplantation with Exocrine Pancreas Bladder Drainage. European urology, 59(3), pp. 462-464. Amsterdam: Elsevier 10.1016/j.eururo.2009.06.025

Fleischmann, Achim; Rocha, Carla; Schobinger, Sylviane; Seiler, Roland; Wiese, Birgitt; Thalmann, George N (2011). Androgen receptors are differentially expressed in Gleason patterns of prostate cancer and down-regulated in matched lymph node metastases. Prostate, 71(5), pp. 453-60. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.21259

Fleischmann, Achim; Rocha, Carla; Saxer-Sekulic, Nikolina; Zlobec, Inti; Sauter, Guido; Thalmann, George N (2011). High CD10 expression in lymph node metastases from surgically treated prostate cancer independently predicts early death. Virchows Archiv, 458(6), pp. 741-8. Berlin: Springer-Verlag 10.1007/s00428-011-1084-z

Fleischmann, Achim; Rocha, Carla; Saxer-Sekulic, Nikolina; Zlobec, Inti; Sauter, Guido; Thalmann, George N (2011). High-level cytoplasmic cyclin D1 expression in lymph node metastases from prostate cancer independently predicts early biochemical failure and death in surgically treated patients. Histopathology, 58(5), pp. 781-9. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2559.2011.03800.x

Seiler, Roland; Thalmann, George N; Fleischmann, Achim (2011). MMP-2 and MMP-9 in lymph-node-positive bladder cancer. Journal of clinical pathology, 64(12), pp. 1078-82. London: BMJ Publishing Group 10.1136/jclinpath-2011-200153

Fleischmann, Achim; Rotzer, Diana; Seiler, Roland; Studer, Urs E; Thalmann, George N (2011). Her2 amplification is significantly more frequent in lymph node metastases from urothelial bladder cancer than in the primary tumours. European urology, 60(2), pp. 350-7. Amsterdam: Elsevier 10.1016/j.eururo.2011.05.035

Reubi, Jean-Claude; Fleischmann, Achim; Waser, Beatrice; Rehmann, Ruth (2011). Concomitant vascular GRP-receptor and VEGF-receptor expression in human tumors: molecular basis for dual targeting of tumoral vasculature. Peptides, 32(7), pp. 1457-62. New York, N.Y.: Elsevier 10.1016/j.peptides.2011.05.007

Seiler, Roland; von Gunten, Michael; Thalmann, George N; Fleischmann, Achim (2011). Extracapsular extension but not the tumour burden of lymph node metastases is an independent adverse risk factor in lymph node-positive bladder cancer. Histopathology, 58(4), pp. 571-8. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2559.2011.03778.x

Seiler, Roland; von Gunten, Michael; Thalmann, George N; Fleischmann, Achim (2010). Pelvic lymph nodes: distribution and nodal tumour burden of urothelial bladder cancer. Journal of clinical pathology, 63(6), pp. 504-7. London: BMJ Publishing Group 10.1136/jcp.2009.075077

Fleischmann, Achim; Waser, Beatrice; Reubi, Jean-Claude (2009). High expression of gastrin-releasing peptide receptors in the vascular bed of urinary tract cancers: promising candidates for vascular targeting applications. Endocrine-related cancer, 16(2), pp. 623-33. Bristol: BioScientifica Ltd. 10.1677/ERC-08-0316

Liniger, Benjamin; Wolf, Rainer Walter; Fleischmann, Achim; Kluwe, Wolfram (2009). Local resection of metanephric adenoma with kidney preservation. Journal of pediatric surgery, 44(8), E21-3. Orlando, Fla.: Elsevier 10.1016/j.jpedsurg.2009.05.028

Fleischmann, Achim; Schlomm, Thorsten; Köllermann, Jens; Sekulic, Nikolina; Huland, Hartwig; Mirlacher, Martina; Sauter, Guido; Simon, Ronald; Erbersdobler, Andreas (2009). Immunological microenvironment in prostate cancer: high mast cell densities are associated with favorable tumor characteristics and good prognosis. Prostate, 69(9), pp. 976-81. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.20948

Thoeny, Harriet C; Triantafyllou, Maria; Birkhaeuser, Frederic D; Froehlich, Johannes M; Tshering, Dechen W; Binser, Tobias; Fleischmann, Achim; Vermathen, Peter; Studer, Urs E (2009). Combined ultrasmall superparamagnetic particles of iron oxide-enhanced and diffusion-weighted magnetic resonance imaging reliably detect pelvic lymph node metastases in normal-sized nodes of bladder and prostate cancer patients. European urology, 55(4), pp. 761-9. Amsterdam: Elsevier 10.1016/j.eururo.2008.12.034

Fleischmann, Achim; Schobinger, Sylviane; Schumacher, Martin; Thalmann, George N; Studer, Urs E (2009). Survival in surgically treated, nodal positive prostate cancer patients is predicted by histopathological characteristics of the primary tumor and its lymph node metastases. Prostate, 69(4), pp. 352-62. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.20889

Marx, Andreas; Wandrey, Timo; Simon, Philipp; Wewer, Agatha; Grob, Tobias; Reichelt, Uta; Minner, Sarah; Simon, Ronald; Spehlmann, Martina; Tigges, Wolfgang; Soehendra, Nib; Seitz, Uwe; Seewald, Stefan; Izbicki, Jakob R; Yekebas, Emre; Kaifi, Jussuf T; Mirlacher, Martina; Terracciano, Luigi; Fleischmann, Achim; Raedler, Andreas; ... (2009). Combined alpha-methylacyl coenzyme A racemase/p53 analysis to identify dysplasia in inflammatory bowel disease. Human pathology, 40(2), pp. 166-73. Philadelphia, Pa.: Elsevier 10.1016/j.humpath.2008.06.027

Fleischmann, Achim; Schlomm, Thorsten; Huland, Hartwig; Köllermann, Jens; Simon, Philipp; Mirlacher, Martina; Salomon, Georg; Chun, Felix H K; Steuber, Thomas; Simon, Ronald; Sauter, Guido; Graefen, Markus; Erbersdobler, Andreas (2008). Distinct subcellular expression patterns of neutral endopeptidase (CD10) in prostate cancer predict diverging clinical courses in surgically treated patients. Clinical cancer research, 14(23), pp. 7838-42. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-1432

Schumacher, Martin C; Burkhard, Fiona C; Thalmann, George N; Fleischmann, Achim; Studer, Urs E (2008). Good outcome for patients with few lymph node metastases after radical retropubic prostatectomy. European urology, 54(2), pp. 344-52. Amsterdam: Elsevier 10.1016/j.eururo.2008.05.023

Beneder, Christine; Kuhn, Annette; ImObersteg, Jeannine; Beer, Karl; Fleischmann, Achim; Mueller, Michael David (2008). Isolated Langerhans cell histiocytosis of the vulva: a case report and review of the literature. Gynecological surgery, 5(2), pp. 165-168. Springer 10.1007/s10397-007-0351-0

Fleischmann, Achim; Waser, Beatrice; Reubi, Jean Claude (2007). Overexpression of gastrin-releasing peptide receptors in tumor-associated blood vessels of human ovarian neoplasms. Cellular oncology, 29(5), pp. 421-33. Amsterdam: IOS Press

Burkhard, Fiona C; Kessler, Thomas M; Fleischmann, Achim; Thalmann, George N; Schumacher, Martin; Studer, Urs E (2006). Nerve sparing open radical retropubic prostatectomy--does it have an impact on urinary continence? Journal of urology, 176(1), pp. 189-95. New York, N.Y.: Elsevier 10.1016/S0022-5347(06)00574-X

Studer, Urs E; Burkhard, Fiona C; Schumacher, Martin; Kessler, Thomas M; Thoeny, Harriet; Fleischmann, Achim; Thalmann, George N (2006). Twenty years experience with an ileal orthotopic low pressure bladder substitute--lessons to be learned. Journal of urology, 176(1), pp. 161-6. New York, N.Y.: Elsevier 10.1016/S0022-5347(06)00573-8

Schumacher, Martin C; Burkhard, Fiona C; Thalmann, George N; Fleischmann, Achim; Studer, Urs E (2006). Is Pelvic Lymph Node Dissection Necessary in Patients with a Serum PSA<10ng/ml Undergoing Radical Prostatectomy for Prostate Cancer? European urology, 50(2), pp. 272-9. Amsterdam: Elsevier 10.1016/j.eururo.2006.01.061

Schumacher, Martin C; Scholz, Michael; Weise, Erik S; Fleischmann, Achim; Thalmann, George N; Studer, Urs E (2006). Is there an indication for frozen section examination of the ureteral margins during cystectomy for transitional cell carcinoma of the bladder? Journal of urology, 176(6 Pt 1), 2409-13; discussion 2413. New York, N.Y.: Elsevier 10.1016/j.juro.2006.07.162

Antonov, Janine; Goldstein, Darlene R; Oberli, Andrea; Baltzer, Anna; Pirotta, Marco; Fleischmann, Achim; Altermatt, Hans J; Jaggi, Rolf (2005). Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization. Laboratory investigation, 85(8), pp. 1040-50. New York, N.Y.: Nature Publishing Group 10.1038/labinvest.3700303

Conference or Workshop Item

Fleischmann, Achim; Seiler, Roland; Zlobec, Inti; Visakorpi, Tapio; Thalmann, George (April 2013). TMPRSS2-ERG Gene Fusion: Frequency and Prognostic Significance in Prostate Cancer Patients with Positive Lymph Nodes. Journal of urology, 189(4), E84-E85. Elsevier

Fleischmann, Achim; Saramaki, O.; Visakorpi, T.; Zlobec, I.; Thalmann, G. N. (2013). Prostate Cancer Cells with TMPRSS2-ERG Gene Fusion or ERG Overexpression Are Not Selected in the Metastatic Process. Laboratory investigation, 93(S1), 210A. Nature Publishing Group

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