Fleischmann, Achim

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Journal Article

Frei, Ana Leni; Oberson, Raphaël; Baumann, Elias; Perren, Aurel; Grobholz, Rainer; Lugli, Alessandro; Dawson, Heather; Abbet, Christian; Lertxundi, Ibai; Reinhard, Stefan; Mookhoek, Aart; Feichtinger, Johann; Sarro, Rossella; Gadient, Gallus; Dommann-Scherrer, Corina; Barizzi, Jessica; Berezowska, Sabina; Glatz, Katharina; Dertinger, Susanne; Banz, Yara; ... (2023). Pathologist computer-aided diagnostic scoring of tumor cell fraction: A Swiss national study. Modern pathology, 36(12), p. 100335. Springer Nature 10.1016/j.modpat.2023.100335

Gallon, John; Rodríguez-Calero, Antonio; Benjak, Andrej; Akhoundova, Dilara; Maletti, Sina; Amstutz, Ursula; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; Bubendorf, Lukas; Moch, Holger; Thalmann, George; Feng, Felix Y; Gillessen, Silke; ... (2023). DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations. Cancer research, 83(8), pp. 1203-1213. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-22-2236

Özdemir, Berna C; Arnold, Nicolas; Fleischmann, Achim; Hensel, Janine; Klima, Irena; Kruithof-de Julio, Marianna; Burkhard, Fiona; Hayoz, Stefanie; Kiss, Bernhard; Thalmann, George N (2022). Prediction of Biochemical Recurrence Based on Molecular Detection of Lymph Node Metastasis After Radical Prostatectomy. European urology open science, 44, pp. 1-10. Elsevier 10.1016/j.euros.2022.07.005

Rodriguez-Calero, Antonio; Gallon, John; Akhoundova, Dilara; Maletti, Sina; Ferguson, Alison; Cyrta, Joanna; Amstutz, Ursula; Garofoli, Andrea; Paradiso, Viola; Tomlins, Scott A; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Vassella, Erik; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; ... (2022). Alterations in homologous recombination repair genes in prostate cancer brain metastases. Nature Communications, 13(1), p. 2400. Springer Nature 10.1038/s41467-022-30003-5

Moskovszky, Linda; Berger, Barbara; Fleischmann, Achim; Friedrich, Thomas; Helmchen, Birgit; Körner, Meike; Rau, Tilman T.; Varga, Zsuzsanna (2020). Inter-observer reproducibility of classical lobular neoplasia (B3 lesions) in preoperative breast biopsies: a study of the Swiss Working Group of breast and gynecopathologists. Journal of cancer research and clinical oncology, 146(6), pp. 1473-1478. Springer 10.1007/s00432-020-03195-w

Savic Prince, Spasenija; Berezowska, Sabina Anna; Eppenberger-Castori, Serenella; Cathomas, Gieri; Diebold, Joachim; Fleischmann, Achim; Jochum, Wolfram; Komminoth, Paul; McKee, Thomas; Letovanec, Igor; Jasarevic, Zerina; Rössle, Matthias; Singer, Gad; von Gunten, Michael; Zettl, Andreas; Zweifel, Roland; Soltermann, Alex; Bubendorf, Lukas (2019). PD-L1 testing of non-small cell lung cancer using different antibodies and platforms: a Swiss cross-validation study. Virchows Archiv, 475(1), pp. 67-76. Springer 10.1007/s00428-019-02582-0

Genitsch Gratwohl, Vera; Zlobec, Inti; Seiler, Roland; Thalmann, George; Fleischmann, Achim (2017). Neuroendocrine Differentiation in Metastatic Conventional Prostate Cancer Is Significantly Increased in Lymph Node Metastases Compared to the Primary Tumors. International journal of molecular sciences, 18(8) Molecular Diversity Preservation International MDPI 10.3390/ijms18081640

Kiss, Bernhard; Wyatt, Alexander W; Douglas, James; Skuginna, Veronika Olga; Mo, Fan; Anderson, Shawn; Rotzer, Diana; Fleischmann, Achim; Genitsch Gratwohl, Vera; Hayashi, Tetsutaro; Neuenschwander, Maja; Buerki, Christine; Davicioni, Elai; Collins, Colin; Thalmann, George; Black, Peter C; Seiler, Roland (2017). Her2 alterations in muscle-invasive bladder cancer: Patient selection beyond protein expression for targeted therapy. Scientific Reports, 7(42713), p. 42713. Nature Publishing Group 10.1038/srep42713

Genitsch Gratwohl, Vera; Zlobec, Inti; Fleischmann, Achim; Thalmann, George (2016). MUC1 in lymph node metastases independently predicts survival in advanced prostate cancer patients. Prostate Cancer Prostatic Diseases, 19(3), pp. 242-247. Springer 10.1038/pcan.2016.11

Hassel, C.; Blaum, K.; Goodacre, T. Day; Dorrer, Holger Johann; Düllmann, Ch. E.; Eberhardt, K.; Eliseev, S.; Enss, C.; Filianin, P.; Fäßler, A.; Fleischmann, Achim; Gastaldo, L.; Goncharov, M.; Hengstler, D.; Jochum, J.; Johnston, K.; Keller, M.; Kempf, S.; Kieck, T.; Köster, U.; ... (2016). Recent Results for the ECHo Experiment. Journal of low temperature physics, 184(3-4), pp. 910-921. Springer 10.1007/s10909-016-1541-9

Ho, Melissa E; Quek, Sue-Ing; True, Lawrence D; Seiler, Roland; Fleischmann, Achim; Bagryanova, Lora; Kim, Sara R; Chia, David; Goodglick, Lee; Shimizu, Yoshiko; Rosser, Charles J; Gao, Yuqian; Liu, Alvin Y (2016). Bladder cancer cells secrete while normal bladder cells express but do not secrete AGR2. OncoTarget, 7(13), pp. 15747-15756. Impact Journals LLC 10.18632/oncotarget.7400

Tschui, Joëlle; Vassella, Erik; Bandi Hess, Nora; Baumgartner, Ulrich; Genitsch Gratwohl, Vera; Rotzer, Diana; Seiler, Roland; Thalmann, George; Fleischmann, Achim (2015). Morphological and molecular characteristics of HER2 amplified urothelial bladder cancer. Virchows Archiv, 466(6), pp. 703-710. Springer 10.1007/s00428-015-1729-4

Kiss, Bernhard; Skuginna, Veronika; Fleischmann, Achim; Bell, Robert H; Collins, Colin; Thalmann, George; Seiler, Roland (2015). Bcl-2 predicts response to neoadjuvant chemotherapy and is overexpressed in lymph node metastases of urothelial cancer of the bladder. Urologic oncology - seminars and original investigations, 33(4), 166.e1-166.e8. Elsevier 10.1016/j.urolonc.2014.12.005

Turo, Rafal; Harnden, Patricia; Thygesen, Helene; Fleischmann, Achim; Thalmann, George; Seiler, Roland; Cross, William R; Knowles, Margaret A (2015). FGFR3 expression in primary invasive bladder cancers and matched lymph node metastases. Journal of urology, 193(1), pp. 325-330. Elsevier 10.1016/j.juro.2014.06.026

Fleischmann, Achim; Saramäki, Outi R; Zlobec, Inti; Rotzer, Diana; Genitsch Gratwohl, Vera; Seiler, Roland; Visakorpi, Tapio; Thalmann, George (2014). Prevalence and prognostic significance of TMPRSS2-ERG gene fusion in lymph node positive prostate cancers. Prostate, 74(16), pp. 1647-1654. Wiley-Blackwell 10.1002/pros.22882

Thöny, Harriet C.; Froehlich, Johannes M; Triantafyllou, Maria; Huesler, Juerg; Bains, Lauren; Vermathen, Peter; Fleischmann, Achim; Studer, Urs (2014). Metastases in normal-sized pelvic lymph nodes: detection with diffusion-weighted MR imaging. Radiology, 273(1), pp. 125-135. Radiological Society of North America RSNA 10.1148/radiol.14132921

Bains, Lauren; Studer, Urs; Froehlich, Johannes M; Giannarini, Gianluca; Triantafyllou, Maria; Fleischmann, Achim; Thöny, Harriet C. (2014). Diffusion-weighted magnetic resonance imaging detects significant prostate cancer with high probability. Journal of urology, 192(3), pp. 737-742. Elsevier 10.1016/j.juro.2014.03.039

Fleischmann, Achim; Thalmann, George; Perren, Aurel; Seiler, Roland (2014). Tumor regression grade of urothelial bladder cancer after neoadjuvant chemotherapy: a novel and successful strategy to predict survival. The American journal of surgical pathology, 38(3), pp. 325-332. Lippincott Williams & Wilkins 10.1097/PAS.0000000000000142

Seiler, Roland; Thalmann, George N.; Rotzer, Diana; Perren, Aurel; Fleischmann, Achim (2014). CCND1/CyclinD1 status in metastasizing bladder cancer: a prognosticator and predictor of chemotherapeutic response. Modern pathology, 27(1), pp. 87-95. Nature Publishing Group 10.1038/modpathol.2013.125

Oezdemir, Berna; Hensel, Janine; Secondini, Chiara; Wetterwald, Antoinette; Schwaninger, Ruth; Fleischmann, Achim; Raffelsberger, Wolfgang; Poch, Olivier; Delorenzi, Mauro; Temanni, Ramzi; Mills, Ian G; van der Pluijm, Gabri; Thalmann, George; Cecchini, Marco Giovanni (2014). The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches. PLoS ONE, 9(12), e114530. Public Library of Science 10.1371/journal.pone.0114530

Mansi, Rosalba; Fleischmann, Achim; Mäcke, Helmut R.; Reubi, Jean-Claude (2013). Targeting GRPR in urological cancers--from basic research to clinical application. Nature Reviews. Urology, 10(4), pp. 235-244. Nature Publishing Group 10.1038/nrurol.2013.42

Triantafyllou, Maria; Studer, Urs E.; Birkhäuser, Frédéric D.; Fleischmann, Achim; Bains, Lauren J.; Petralia, Giuseppe; Christe, Andreas; Fröhlich, Johannes M.; Thoeny, Harriet C. (2013). Ultrasmall superparamagnetic particles of iron oxide allow for the detection of metastases in normal sized pelvic lymph nodes of patients with bladder and/or prostate cancer. European journal of cancer, 49(3), pp. 616-624. Amsterdam: Elsevier 10.1016/j.ejca.2012.09.034

Birkhäuser, Frédéric D.; Studer, Urs E.; Froehlich, Johannes M.; Triantafyllou, Maria; Bains, Lauren J.; Petralia, Giuseppe; Vermathen, Peter; Fleischmann, Achim; Thoeny, Harriet C. (2013). Combined Ultrasmall Superparamagnetic Particles of Iron Oxide–Enhanced and Diffusion-weighted Magnetic Resonance Imaging Facilitates Detection of Metastases in Normal-sized Pelvic Lymph Nodes of Patients with Bladder and Prostate Cancer. European urology, 64(6), pp. 953-960. Elsevier 10.1016/j.eururo.2013.07.032

Seiler, Roland; von Gunten, Michael; Thalmann, George N; Fleischmann, Achim (2012). High CD10 expression predicts favorable outcome in surgically treated lymph node-positive bladder cancer patients. Human pathology, 43(2), pp. 269-75. Philadelphia, Pa.: Elsevier 10.1016/j.humpath.2011.04.030

Froehlich, Johannes M; Triantafyllou, Maria; Fleischmann, Achim; Vermathen, Peter; Thalmann, George N; Thoeny, Harriet C (2012). Does quantification of USPIO uptake-related signal loss allow differentiation of benign and malignant normal-sized pelvic lymph nodes? Contrast media & molecular imaging, 7(3), pp. 346-55. Chichester: Wiley 10.1002/cmmi.503

Matter, Alexandra; Hewer, Ekkehard; Kappeler, Andreas; Fleischmann, Achim; Vajtai, Istvan (2012). Plexiform hybrid granular cell tumor/perineurioma: a novel variant of benign peripheral nerve sheath tumor with divergent differentiation. Pathology, research and practice, 208(5), pp. 310-4. München: Elsevier 10.1016/j.prp.2012.02.014

Kiss, Bernhard; Birkhäuser, Frédéric D.; Fleischmann, Achim; Candinas, Daniel; Studer, Urs E.; Kessler, Thomas M. (2011). Refractory Hematuria in an Oliguric Patient After Pancreas Transplantation with Exocrine Pancreas Bladder Drainage. European urology, 59(3), pp. 462-464. Amsterdam: Elsevier 10.1016/j.eururo.2009.06.025

Fleischmann, Achim; Rocha, Carla; Schobinger, Sylviane; Seiler, Roland; Wiese, Birgitt; Thalmann, George N (2011). Androgen receptors are differentially expressed in Gleason patterns of prostate cancer and down-regulated in matched lymph node metastases. Prostate, 71(5), pp. 453-60. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.21259

Fleischmann, Achim; Rocha, Carla; Saxer-Sekulic, Nikolina; Zlobec, Inti; Sauter, Guido; Thalmann, George N (2011). High CD10 expression in lymph node metastases from surgically treated prostate cancer independently predicts early death. Virchows Archiv, 458(6), pp. 741-8. Berlin: Springer-Verlag 10.1007/s00428-011-1084-z

Fleischmann, Achim; Rocha, Carla; Saxer-Sekulic, Nikolina; Zlobec, Inti; Sauter, Guido; Thalmann, George N (2011). High-level cytoplasmic cyclin D1 expression in lymph node metastases from prostate cancer independently predicts early biochemical failure and death in surgically treated patients. Histopathology, 58(5), pp. 781-9. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2559.2011.03800.x

Seiler, Roland; Thalmann, George N; Fleischmann, Achim (2011). MMP-2 and MMP-9 in lymph-node-positive bladder cancer. Journal of clinical pathology, 64(12), pp. 1078-82. London: BMJ Publishing Group 10.1136/jclinpath-2011-200153

Fleischmann, Achim; Rotzer, Diana; Seiler, Roland; Studer, Urs E; Thalmann, George N (2011). Her2 amplification is significantly more frequent in lymph node metastases from urothelial bladder cancer than in the primary tumours. European urology, 60(2), pp. 350-7. Amsterdam: Elsevier 10.1016/j.eururo.2011.05.035

Reubi, Jean-Claude; Fleischmann, Achim; Waser, Beatrice; Rehmann, Ruth (2011). Concomitant vascular GRP-receptor and VEGF-receptor expression in human tumors: molecular basis for dual targeting of tumoral vasculature. Peptides, 32(7), pp. 1457-62. New York, N.Y.: Elsevier 10.1016/j.peptides.2011.05.007

Seiler, Roland; von Gunten, Michael; Thalmann, George N; Fleischmann, Achim (2011). Extracapsular extension but not the tumour burden of lymph node metastases is an independent adverse risk factor in lymph node-positive bladder cancer. Histopathology, 58(4), pp. 571-8. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2559.2011.03778.x

Seiler, Roland; von Gunten, Michael; Thalmann, George N; Fleischmann, Achim (2010). Pelvic lymph nodes: distribution and nodal tumour burden of urothelial bladder cancer. Journal of clinical pathology, 63(6), pp. 504-7. London: BMJ Publishing Group 10.1136/jcp.2009.075077

Fleischmann, Achim; Waser, Beatrice; Reubi, Jean-Claude (2009). High expression of gastrin-releasing peptide receptors in the vascular bed of urinary tract cancers: promising candidates for vascular targeting applications. Endocrine-related cancer, 16(2), pp. 623-33. Bristol: BioScientifica Ltd. 10.1677/ERC-08-0316

Liniger, Benjamin; Wolf, Rainer Walter; Fleischmann, Achim; Kluwe, Wolfram (2009). Local resection of metanephric adenoma with kidney preservation. Journal of pediatric surgery, 44(8), E21-3. Orlando, Fla.: Elsevier 10.1016/j.jpedsurg.2009.05.028

Fleischmann, Achim; Schlomm, Thorsten; Köllermann, Jens; Sekulic, Nikolina; Huland, Hartwig; Mirlacher, Martina; Sauter, Guido; Simon, Ronald; Erbersdobler, Andreas (2009). Immunological microenvironment in prostate cancer: high mast cell densities are associated with favorable tumor characteristics and good prognosis. Prostate, 69(9), pp. 976-81. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.20948

Thoeny, Harriet C; Triantafyllou, Maria; Birkhaeuser, Frederic D; Froehlich, Johannes M; Tshering, Dechen W; Binser, Tobias; Fleischmann, Achim; Vermathen, Peter; Studer, Urs E (2009). Combined ultrasmall superparamagnetic particles of iron oxide-enhanced and diffusion-weighted magnetic resonance imaging reliably detect pelvic lymph node metastases in normal-sized nodes of bladder and prostate cancer patients. European urology, 55(4), pp. 761-9. Amsterdam: Elsevier 10.1016/j.eururo.2008.12.034

Fleischmann, Achim; Schobinger, Sylviane; Schumacher, Martin; Thalmann, George N; Studer, Urs E (2009). Survival in surgically treated, nodal positive prostate cancer patients is predicted by histopathological characteristics of the primary tumor and its lymph node metastases. Prostate, 69(4), pp. 352-62. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.20889

Marx, Andreas; Wandrey, Timo; Simon, Philipp; Wewer, Agatha; Grob, Tobias; Reichelt, Uta; Minner, Sarah; Simon, Ronald; Spehlmann, Martina; Tigges, Wolfgang; Soehendra, Nib; Seitz, Uwe; Seewald, Stefan; Izbicki, Jakob R; Yekebas, Emre; Kaifi, Jussuf T; Mirlacher, Martina; Terracciano, Luigi; Fleischmann, Achim; Raedler, Andreas; ... (2009). Combined alpha-methylacyl coenzyme A racemase/p53 analysis to identify dysplasia in inflammatory bowel disease. Human pathology, 40(2), pp. 166-73. Philadelphia, Pa.: Elsevier 10.1016/j.humpath.2008.06.027

Fleischmann, Achim; Schlomm, Thorsten; Huland, Hartwig; Köllermann, Jens; Simon, Philipp; Mirlacher, Martina; Salomon, Georg; Chun, Felix H K; Steuber, Thomas; Simon, Ronald; Sauter, Guido; Graefen, Markus; Erbersdobler, Andreas (2008). Distinct subcellular expression patterns of neutral endopeptidase (CD10) in prostate cancer predict diverging clinical courses in surgically treated patients. Clinical cancer research, 14(23), pp. 7838-42. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-1432

Schumacher, Martin C; Burkhard, Fiona C; Thalmann, George N; Fleischmann, Achim; Studer, Urs E (2008). Good outcome for patients with few lymph node metastases after radical retropubic prostatectomy. European urology, 54(2), pp. 344-52. Amsterdam: Elsevier 10.1016/j.eururo.2008.05.023

Beneder, Christine; Kuhn, Annette; ImObersteg, Jeannine; Beer, Karl; Fleischmann, Achim; Mueller, Michael David (2008). Isolated Langerhans cell histiocytosis of the vulva: a case report and review of the literature. Gynecological surgery, 5(2), pp. 165-168. Springer 10.1007/s10397-007-0351-0

Fleischmann, Achim; Waser, Beatrice; Reubi, Jean Claude (2007). Overexpression of gastrin-releasing peptide receptors in tumor-associated blood vessels of human ovarian neoplasms. Cellular oncology, 29(5), pp. 421-33. Amsterdam: IOS Press

Burkhard, Fiona C; Kessler, Thomas M; Fleischmann, Achim; Thalmann, George N; Schumacher, Martin; Studer, Urs E (2006). Nerve sparing open radical retropubic prostatectomy--does it have an impact on urinary continence? Journal of urology, 176(1), pp. 189-95. New York, N.Y.: Elsevier 10.1016/S0022-5347(06)00574-X

Studer, Urs E; Burkhard, Fiona C; Schumacher, Martin; Kessler, Thomas M; Thoeny, Harriet; Fleischmann, Achim; Thalmann, George N (2006). Twenty years experience with an ileal orthotopic low pressure bladder substitute--lessons to be learned. Journal of urology, 176(1), pp. 161-6. New York, N.Y.: Elsevier 10.1016/S0022-5347(06)00573-8

Schumacher, Martin C; Burkhard, Fiona C; Thalmann, George N; Fleischmann, Achim; Studer, Urs E (2006). Is Pelvic Lymph Node Dissection Necessary in Patients with a Serum PSA<10ng/ml Undergoing Radical Prostatectomy for Prostate Cancer? European urology, 50(2), pp. 272-9. Amsterdam: Elsevier 10.1016/j.eururo.2006.01.061

Schumacher, Martin C; Scholz, Michael; Weise, Erik S; Fleischmann, Achim; Thalmann, George N; Studer, Urs E (2006). Is there an indication for frozen section examination of the ureteral margins during cystectomy for transitional cell carcinoma of the bladder? Journal of urology, 176(6 Pt 1), 2409-13; discussion 2413. New York, N.Y.: Elsevier 10.1016/j.juro.2006.07.162

Antonov, Janine; Goldstein, Darlene R; Oberli, Andrea; Baltzer, Anna; Pirotta, Marco; Fleischmann, Achim; Altermatt, Hans J; Jaggi, Rolf (2005). Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization. Laboratory investigation, 85(8), pp. 1040-50. New York, N.Y.: Nature Publishing Group 10.1038/labinvest.3700303

Conference or Workshop Item

Fleischmann, Achim; Seiler, Roland; Zlobec, Inti; Visakorpi, Tapio; Thalmann, George (April 2013). TMPRSS2-ERG Gene Fusion: Frequency and Prognostic Significance in Prostate Cancer Patients with Positive Lymph Nodes. Journal of urology, 189(4), E84-E85. Elsevier

Fleischmann, Achim; Saramaki, O.; Visakorpi, T.; Zlobec, I.; Thalmann, G. N. (2013). Prostate Cancer Cells with TMPRSS2-ERG Gene Fusion or ERG Overexpression Are Not Selected in the Metastatic Process. Laboratory investigation, 93(S1), 210A. Nature Publishing Group

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