Klimkait, Thomas

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Journal Article

Chaudron, Sandra E; Leemann, Christine; Kusejko, Katharina; Nguyen, Huyen; Tschumi, Nadine; Marzel, Alex; Huber, Michael; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Ramette, Alban; Hirsch, Hans H; Rauch, Andri; Calmy, Alexandra; Vernazza, Pietro; Bernasconi, Enos; Cavassini, Matthias; Metzner, Karin J; Kouyos, Roger D; ... (2022). A systematic molecular epidemiology screen reveals numerous HIV-1 superinfections in the Swiss HIV Cohort Study. The journal of infectious diseases, 226(7), pp. 1256-1266. Oxford University Press 10.1093/infdis/jiac166

Nadeau, Sarah; Thorball, Christian W; Kouyos, Roger; Günthard, Huldrych F; Böni, Jürg; Yerly, Sabine; Perreau, Matthieu; Klimkait, Thomas; Rauch, Andri; Hirsch, Hans H; Cavassini, Matthias; Vernazza, Pietro; Bernasconi, Enos; Fellay, Jacques; Mitov, Venelin; Stadler, Tanja (2022). A phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits. Molecular Biology and Evolution, 39(8) Oxford University Press 10.1093/molbev/msac163

Kusejko, Katharina; Tschumi, Nadine; Chaudron, Sandra E; Nguyen, Huyen; Battegay, Manuel; Bernasconi, Enos; Böni, Jürg; Huber, Michael; Calmy, Alexandra; Cavassini, Matthias; Egle, Alexander; Grabmeier-Pfistershammer, Katharina; Haas, Bernhard; Hirsch, Hans; Klimkait, Thomas; Öllinger, Angela; Perreau, Matthieu; Ramette, Alban; Flury, Baharak Babouee; Sarcletti, Mario; ... (2022). Similar but different: Integrated phylogenetic analysis of Austrian and Swiss HIV-1 sequences reveal differences in transmission patterns of the local HIV-1 epidemics. Journal of acquired immune deficiency syndromes, 90(4), e4-e12. Wolters Kluwer Health 10.1097/QAI.0000000000002949

Bachmann, Nadine; Kusejko, Katharina; Nguyen, Huyen; Chaudron, Sandra E; Kadelka, Claus; Turk, Teja; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Battegay, Manuel; Rauch, Andri; Ramette, Alban; Vernazza, Pietro; Bernasconi, Enos; Cavassini, Matthias; Günthard, Huldrych F; Kouyos, Roger D (2021). Phylogenetic Cluster Analysis Identifies Virological and Behavioral Drivers of HIV Transmission in MSM. Clinical infectious diseases, 72(12), pp. 2175-2183. Oxford University Press 10.1093/cid/ciaa411

Glass, Tracy R; Günthard, Huldrych; Calmy, Alexandra; Bernasconi, Enos; Scherrer, Alexandra U; Battegay, Manuel; Steffen, Ana; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Cavassini, Matthias; Furrer, Hansjakob (2021). The role of HIV asymptomatic status when starting ART on adherence and treatment outcomes and implications for test and treat: the Swiss HIV Cohort Study. Clinical infectious diseases, 72(8), pp. 1413-1421. Oxford University Press 10.1093/cid/ciaa239

Wan, Chenjie; Bachmann, Nadine; Mitov, Venelin; Blanquart, François; Céspedes, Susana Posada; Turk, Teja; Neumann, Kathrin; Beerenwinkel, Niko; Bogojeska, Jasmina; Fellay, Jacques; Roth, Volker; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Battegay, Manuel; Walti, Laura; Calmy, Alexandra; Vernazza, Pietro; Bernasconi, Enos; ... (2020). Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART. Nature communications, 11(1), p. 5542. Nature Publishing Group 10.1038/s41467-020-19198-7

Thorball, Christian W; Borghesi, Alessandro; Bachmann, Nadine; Von Siebenthal, Chantal; Vongrad, Valentina; Turk, Teja; Neumann, Kathrin; Beerenwinkel, Niko; Bogojeska, Jasmina; Roth, Volker; Kok, Yik Lim; Parbhoo, Sonali; Wieser, Mario; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Battegay, Manuel; Rauch, Andri; Schmid, Patrick; ... (2020). Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment. Journal of acquired immune deficiency syndromes, 85(4), pp. 517-524. Wolters Kluwer Health 10.1097/QAI.0000000000002473

Abela, Irene A; Scherrer, Alexandra U; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Perreau, Matthieu; Hirsch, Hans H; Furrer, Hansjakob; Calmy, Alexandra; Schmid, Patrick; Cavassini, Matthias; Bernasconi, Enos; Günthard, Huldrych F (2020). Emergence of drug resistance in the Swiss HIV Cohort Study under potent antiretroviral therapy is observed in socially disadvantaged patients. Clinical infectious diseases, 70(2), pp. 297-303. Oxford University Press 10.1093/cid/ciz178

Kusejko, Katharina; Marzel, Alex; Nguyen, Huyen; Chaudron, Sandra E; Bachmann, Nadine; Weber, Rainer; Bruggmann, Philip; Roth, Jan A; Bernasconi, Enos; Calmy, Alexandra; Cavassini, Matthias; Bregenzer, Andrea; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Perreau, Matthieu; Walti, Laura N.; Günthard, Huldrych F; Kouyos, Roger D (2020). Differences in social and mental well-being of long-term survivors among people who inject drugs and other participants in the Swiss HIV Cohort Study: 1980-2018. Antiviral therapy, 25(1), pp. 43-54. International Medical Press 10.3851/IMP3347

Nguyen, Huyen; Thorball, Christian W; Fellay, Jacques; Böni, Jürg; Yerly, Sabine; Perreau, Matthieu; Klimkait, Thomas; Kusjeko, Katharina; Bachmann, Nadine; Chaudron, Sandra E; Paioni, Paolo; Thurnheer Zürcher, Maria Christine; Battegay, Manuel; Cavassini, Matthias; Vernazza, Pietro; Bernasconi, Enos; Günthard, Huldrych F; Kouyos, Roger (2019). HIV transmission chains exhibit greater HLA-B homogeneity than randomly expected. Journal of acquired immune deficiency syndromes JAIDS, 81(5), pp. 508-515. Lippincott Williams & Wilkins 10.1097/QAI.0000000000002077

Bachmann, Nadine; von Siebenthal, Chantal; Vongrad, Valentina; Turk, Teja; Neumann, Kathrin; Beerenwinkel, Niko; Bogojeska, Jasmina; Fellay, Jaques; Roth, Volker; Kok, Yik Lim; Thorball, Christian W; Borghesi, Alessandro; Parbhoo, Sonali; Wieser, Mario; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Battegay, Manuel; Rauch, Andri; ... (2019). Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART. Nature communications, 10(1), pp. 1-11. Nature Publishing Group 10.1038/s41467-019-10884-9

Kusejko, Katharina; Bachmann, Nadine; Chaudron, Sandra E; Nguyen, Huyen; Braun, Dominique L; Hampel, Benjamin; Battegay, Manuel; Bernasconi, Enos; Calmy, Alexandra; Cavassini, Matthias; Hoffmann, Matthias; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Perreau, Matthieu; Rauch, Andri; Günthard, Huldrych F; Kouyos, Roger D (2019). A systematic phylogenetic approach to study the interaction of HIV-1 with coinfections, non-communicable and opportunistic diseases. The journal of infectious diseases, 220(2), pp. 244-253. Oxford University Press 10.1093/infdis/jiz093

Carlisle, Louisa A; Turk, Teja; Kusejko, Katharina; Metzner, Karin J; Leemann, Christine; Schenkel, Corinne; Bachmann, Nadine; Posada, Susana; Beerenwinkel, Niko; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Perreau, Matthieu; Braun, Dominique L; Rauch, Andri; Calmy, Alexandra; Cavassini, Matthias; Battegay, Manuel; Vernazza, Pietro; Bernasconi, Enos; ... (2019). Viral diversity from next-generation sequencing of HIV-1 samples provides precise estimates of infection recency and time since infection. The journal of infectious diseases, 220(2), pp. 254-265. Oxford University Press 10.1093/infdis/jiz094

Kouyos, Roger D; Rusert, Peter; Kadelka, Claus; Huber, Michael; Marzel, Alex; Ebner, Hanna; Schanz, Merle; Liechti, Thomas; Friedrich, Nikolas; Braun, Dominique L; Scherrer, Alexandra U; Weber, Jacqueline; Uhr, Therese; Baumann, Nicolas S; Leemann, Christine; Kuster, Herbert; Chave, Jean-Philippe; Cavassini, Matthias; Bernasconi, Enos; Hoffmann, Matthias; ... (2018). Tracing HIV-1 strains that imprint broadly neutralizing antibody responses. Nature, 561(7723), pp. 406-410. Macmillan Journals Ltd. 10.1038/s41586-018-0517-0

Kusejko, Katharina; Kadelka, Claus; Marzel, Alex; Battegay, Manuel; Bernasconi, Enos; Calmy, Alexandra; Cavassini, Matthias; Hoffmann, Matthias; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Perreau, Matthieu; Rauch, Andri; Günthard, Huldrych F; Kouyos, Roger D (2018). Inferring the age difference in HIV transmission pairs by applying phylogenetic methods on the HIV transmission network of the Swiss HIV Cohort Study. Virus evolution, 4(2), vey024. Oxford University Press 10.1093/ve/vey024

Kadelka, Claus; Liechti, Thomas; Ebner, Hanna; Schanz, Merle; Rusert, Peter; Friedrich, Nikolas; Stiegeler, Emanuel; Braun, Dominique L; Huber, Michael; Scherrer, Alexandra U; Weber, Jacqueline; Uhr, Therese; Kuster, Herbert; Misselwitz, Benjamin; Cavassini, Matthias; Bernasconi, Enos; Hoffmann, Matthias; Calmy, Alexandra; Battegay, Manuel; Rauch, Andri; ... (2018). Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity. Journal of experimental medicine, 215(6), pp. 1589-1608. Rockefeller University Press 10.1084/jem.20180246

Marzel, Alex; Kusejko, Katharina; Weber, Rainer; Bruggmann, Philip; Rauch, Andri; Roth, Jan A; Bernasconi, Enos; Calmy, Alexandra; Cavassini, Matthias; Hoffmann, Matthias; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Perreau, Matthieu; Günthard, Huldrych F; Kouyos, Roger D (2018). The Cumulative Impact of Harm Reduction on the Swiss HIV Epidemic: Cohort Study, Mathematical Model, and Phylogenetic Analysis. Open Forum Infectious Diseases, 5(5), ofy078. Oxford University Press 10.1093/ofid/ofy078

Bertels, Frederic; Marzel, Alex; Leventhal, Gabriel; Mitov, Venelin; Fellay, Jacques; Günthard, Huldrych F; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Battegay, Manuel; Rauch, Andri; Cavassini, Matthias; Calmy, Alexandra; Bernasconi, Enos; Schmid, Patrick; Scherrer, Alexandra U; Müller, Viktor; Bonhoeffer, Sebastian; Kouyos, Roger; ... (2018). Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T Cell Decline and Per-Parasite Pathogenicity. Molecular Biology and Evolution, 35(1), pp. 27-37. Oxford University Press 10.1093/molbev/msx246

Turk, Teja; Bachmann, Nadine; Kadelka, Claus; Böni, Jürg; Yerly, Sabine; Aubert, Vincent; Klimkait, Thomas; Battegay, Manuel; Bernasconi, Enos; Calmy, Alexandra; Cavassini, Matthias; Furrer, Hansjakob; Hoffmann, Matthias; Günthard, Huldrych F; Kouyos, Roger D (2017). Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis. eLife, 6 eLife Sciences Publications 10.7554/eLife.28721

Letang, Emilio; Kalinjuma, Aneth Vedastus; Glass, Tracy R; Gamell, Anna; Mapesi, Herry; Sikalengo, George Rocky; Luwanda, Lameck Bonaventure; Mnzava, Dorcas; Ntamatungiro, Alex J; Ndaki, Regina; Francis, Gideon; Vanobberghen, Fiona; Furrer, Hansjakob; Klimkait, Thomas; Felger, Ingrid; Tanner, Marcel; Hatz, Christoph; Weisser, Maja; Battegay, Manuel (2017). Cohort profile: The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) - A prospective HIV cohort in rural Tanzania. Swiss medical weekly, 147, w14485. EMH Schweizerischer Ärzteverlag 10.4414/smw.2017.14485

Ntamatungiro, Alex J; Muri, Lukas; Glass, Tracy R; Erb, Stefan; Battegay, Manuel; Furrer, Hansjakob; Hatz, Christoph; Tanner, Marcel; Felger, Ingrid; Klimkait, Thomas; Letang, Emilio (2017). Strengthening HIV therapy and care in rural Tanzania affects rates of viral suppression. Journal of antimicrobial chemotherapy, 72(7), pp. 2069-2074. Oxford University Press 10.1093/jac/dkx095

Bader, Joëlle; Däumer, Martin; Schöni-Affolter, Franziska; Böni, Jürg; Gorgievski, Meri; Martinetti, Gladys; Thielen, Alexander; Klimkait, Thomas (2017). Therapeutic Immune Recovery and Reduction of CXCR4-Tropic HIV-1. Clinical infectious diseases, 64(3), pp. 295-300. Oxford University Press 10.1093/cid/ciw737

Rusert, Peter; Kouyos, Roger D; Kadelka, Claus; Ebner, Hanna; Schanz, Merle; Huber, Michael; Braun, Dominique L; Hozé, Nathanael; Scherrer, Alexandra; Magnus, Carsten; Weber, Jacqueline; Uhr, Therese; Cippa, Valentina; Thorball, Christian W; Kuster, Herbert; Cavassini, Matthias; Bernasconi, Enos; Hoffmann, Matthias; Calmy, Alexandra; Battegay, Manuel; ... (2016). Determinants of HIV-1 broadly neutralizing antibody induction. Nature medicine, 22(11), pp. 1260-1267. Nature Publishing Group 10.1038/nm.4187

Muri, Lukas; Gamell, Anna; Ntamatungiro, Alex J; Glass, Tracy R; Luwanda, Lameck B; Battegay, Manuel; Furrer, Hansjakob; Hatz, Christoph; Tanner, Marcel; Felger, Ingrid; Klimkait, Thomas; Letang, Emilio (2016). Development of HIV drug resistance and therapeutic failure in children and adolescents in rural tanzania - an emerging public health concern. AIDS, 31(1), pp. 61-70. Lippincott Williams & Wilkins 10.1097/QAD.0000000000001273

Scherrer, Alexandra U; Yang, Wan-Lin; Kouyos, Roger D; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Cavassini, Matthias; Battegay, Manuel; Hauser, Christoph; Calmy, Alexandra; Schmid, Patrick; Bernasconi, Enos; Günthard, Huldrych F (2016). Successful prevention of transmission of integrase resistance in the Swiss HIV Cohort Study. Journal of infectious diseases, 214(3), pp. 399-402. Oxford University Press 10.1093/infdis/jiw165

Scherrer, Alexandra U; von Wyl, Viktor; Yang, Wan-Lin; Kouyos, Roger; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Cavassini, Matthias; Battegay, Manuel; Furrer, Hansjakob; Calmy, Alexandra; Vernazza, Pietro; Bernasconi, Enos; Günthard, Huldrych F (2016). Emergence of acquired HIV-1 drug resistance has almost been stopped in Switzerland - a 15 year prospective cohort analysis. Clinical infectious diseases, 62(10), pp. 1310-1317. Oxford University Press 10.1093/cid/ciw128

Marzel, Alex; Shilaih, Mohaned; Yang, Wan-Lin; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Braun, Dominique L; Calmy, Alexandra; Furrer, Hansjakob; Cavassini, Matthias; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Günthard, Huldrych F; Kouyos, Roger D (2016). HIV-1 Transmission During Recent Infection and During Treatment Interruptions as Major Drivers of New Infections in the Swiss HIV Cohort Study. Clinical infectious diseases, 62(1), pp. 115-122. Oxford University Press 10.1093/cid/civ732

Shilaih, Mohaned; Marzel, Alex; Yang, Wan Lin; Scherrer, Alexandra U; Schüpbach, Jörg; Böni, Jürg; Yerly, Sabine; Hirsch, Hans H; Aubert, Vincent; Cavassini, Matthias; Klimkait, Thomas; Vernazza, Pietro L; Bernasconi, Enos; Furrer, Hansjakob; Günthard, Huldrych F; Kouyos, Roger (2016). Genotypic Resistance Tests Sequences Reveal the Role of Marginalized Populations in HIV-1 Transmission in Switzerland. Scientific Reports, 6(27580), p. 27580. Nature Publishing Group 10.1038/srep27580

Schüpbach, Jörg; Niederhauser, Christoph; Yerly, Sabine; Regenass, Stephan; Gorgievski, Meri; Aubert, Vincent; Ciardo, Diana; Klimkait, Thomas; Dollenmaier, Günter; Andreutti, Corinne; Martinetti, Gladys; Brandenberger, Marcel; Gebhardt, Martin D. (2015). Decreasing Proportion of Recent Infections among Newly Diagnosed HIV-1 Cases in Switzerland, 2008 to 2013 Based on Line-Immunoassay-Based Algorithms. PLoS ONE, 10(7), e0131828. Public Library of Science 10.1371/journal.pone.0131828

Yang, Wan-Lin; Kouyos, Roger; Scherrer, Alexandra U; Böni, Jürg; Shah, Cyril; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Furrer, Hansjakob; Battegay, Manuel; Cavassini, Matthias; Bernasconi, Enos; Vernazza, Pietro; Held, Leonhard; Ledergerber, Bruno; Günthard, Huldrych F (2015). Assessing the paradox between transmitted and acquired HIV-1 drug resistance in the Swiss HIV Cohort Study from 1998 to 2012. Journal of infectious diseases, 212(1), pp. 28-38. Oxford University Press 10.1093/infdis/jiv012

Yang, Wan-Lin; Kouyos, Roger D; Scherrer, Alexandra U; Böni, Jürg; Shah, Cyril; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Hirzel, Cédric; Battegay, Manuel; Cavassini, Matthias; Bernasconi, Enos; Vernazza, Pietro; Held, Leonhard; Ledergerber, Bruno; Günthard, Huldrych F (2015). Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study. Journal of antimicrobial chemotherapy, 70(12), pp. 3323-3331. Oxford University Press 10.1093/jac/dkv257

Metzner, Karin J.; Scherrer, Alexandra U.; Von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Furrer, Hansjakob; Hirsch, Hans H.; Vernazza, Pietro L.; Cavassini, Matthias; Calmy, Alexandra; Bernasconi, Enos; Weber, Rainer; Günthard, Huldrych F. (2014). Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients. AIDS, 28(15), pp. 2231-2239. Lippincott Williams & Wilkins 10.1097/QAD.0000000000000397

Avila, Dorita; Keiser, Olivia; Egger, Matthias; Kouyos, Roger; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Vernazza, Pietro L; Aubert, Vincent; Rauch, Andri; Bonhoeffer, Sebastian; Günthard, Huldrych F; Stadler, Tanja; Spycher, Ben D (2014). Social Meets Molecular: Combining Phylogenetic and Latent Class Analyses to Understand HIV-1 Transmission in Switzerland. American journal of epidemiology, 179(12), pp. 1514-1525. Oxford University Press 10.1093/aje/kwu076

Drescher, Sara M; von Wyl, Viktor; Yang, Wan-Lin; Böni, Jürg; Yerly, Sabine; Shah, Cyril; Aubert, Vincent; Klimkait, Thomas; Taffé, Patrick; Furrer, Hansjakob; Battegay, Manuel; Ambrosioni, Juan; Cavassini, Matthias; Bernasconi, Enos; Vernazza, Pietro L; Ledergerber, Bruno; Günthard, Huldrych F; Kouyos, Roger D; Egger, M; Keiser, O; ... (2014). Treatment-naive individuals are the major source of transmitted HIV-1 drug resistance in men who have sex with men in the Swiss HIV Cohort Study. Clinical infectious diseases, 58(2), pp. 285-94. Oxford University Press 10.1093/cid/cit694

Kouyos, Roger D; Rauch, Andri; Böni, Jürg; Yerly, Sabine; Shah, Cyril; Aubert, Vincent; Klimkait, Thomas; Kovari, Helen; Calmy, Alexandra; Cavassini, Matthias; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Ledergerber, Bruno; Günthard, Huldrych F; Egger, Matthias; Furrer, Hansjakob; Keiser, Olivia; Schöni-Affolter, Franziska and Swiss HIV Cohort, Study (2014). Clustering of HCV coinfections on HIV phylogeny indicates domestic and sexual transmission of HCV. International journal of epidemiology, 43(3), pp. 887-896. Oxford University Press 10.1093/ije/dyt276

Kouyos, Roger D; Rauch, Andri; Braun, Dominique L; Yang, Wan-Lin; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Shah, Cyril; Kovari, Helen; Calmy, Alexandra; Cavassini, Matthias; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Ledergerber, Bruno; Günthard, Huldrych F (2014). Higher Risk of Incident HCV-Coinfections in MSM with a Wide HIV Transmission Bottleneck. Journal of infectious diseases, 210(10), pp. 1555-1561. Oxford University Press 10.1093/infdis/jiu315

Vetter, Beatrice N; Orlowski, Vanessa; Fransen, Katrien; Niederhauser, Christoph; Aubert, Vincent; Brandenberger, Marcel; Ciardo, Diana; Dollenmaier, Günter; Klimkait, Thomas; Regenass, Stephan; Schmid, Patrick; Schottstedt, Volkmar; Suter-Riniker, Franziska; Yerly, Sabine; Shah, Cyril; Böni, Jürg; Schüpbach, Jörg (2014). Generation of a recombinant Gag virus-like-particle panel for the evaluation of p24 antigen detection by diagnostic HIV tests. PLoS ONE, 9(10), e111552. Public Library of Science 10.1371/journal.pone.0111552

von Wyl, Viktor; Klimkait, Thomas; Yerly, Sabine; Nicca, Dunja; Furrer, Hansjakob; Cavassini, Matthias; Calmy, Alexandra; Bernasconi, Enos; Böni, Jürg; Aubert, Vincent; Günthard, Huldrych F.; Bucher, Heiner C.; Glass, Tracy R.; Wainberg, Mark (2013). Adherence as a Predictor of the Development of Class-Specific Resistance Mutations: The Swiss HIV Cohort Study. PLoS ONE, 8(10), e77691. Public Library of Science 10.1371/journal.pone.0077691

Schüpbach, Jörg; Gebhardt, Martin D.; Scherrer, Alexandra U.; Bisset, Leslie R.; Niederhauser, Christoph; Regenass, Stephan; Yerly, Sabine; Aubert, Vincent; Suter, Franziska Marta; Pfister, Stefan; Marinetti, Gladys; Andreutti, Corinne; Klimkait, Thomas; Brandenberger, Marcel; Günthard, Huldrych F. (2013). Simple Estimation of Incident HIV Infection Rates in Notification Cohorts Based on Window Periods of Algorithms for Evaluation of Line-Immunoassay Result Patterns. PLoS ONE, 8(8), e71662. Public Library of Science 10.1371/journal.pone.0071662

Beerenwinkel, Niko; Montazeri, Hesam; Schuhmacher, Heike; Knupfer, Patrick; von Wyl, Viktor; Furrer, Hansjakob; Battegay, Manuel; Hirschel, Bernard; Cavassini, Matthias; Vernazza, Pietro; Bernasconi, Enos; Yerly, Sabine; Böni, Jürg; Klimkait, Thomas; Cellerai, Cristina; Günthard, Huldrych F.; Vandamme, Anne-Mieke (2013). The Individualized Genetic Barrier Predicts Treatment Response in a Large Cohort of HIV-1 Infected Patients. PLoS computational biology, 9(8), e1003203. Public Library of Science 10.1371/journal.pcbi.1003203

Cusini, Alexia; Vernazza, Pietro L.; Yerly, Sabine; Decosterd, Laurent A.; Ledergerber, Bruno; Fux, Christoph A.; Rohrbach, Janine; Widmer, Nicolas; Hirschel, Bernhard; Gaudenz, Roman; Cavassini, Matthias; Klimkait, Thomas; Zenger, Franziska; Gutmann, Chistine; Opravil, Milos; Günthard, Huldyrich F. (2013). Higher CNS Penetration-Effectiveness of Long-term Combination Antiretroviral Therapy Is Associated With Better HIV-1 Viral Suppression in Cerebrospinal Fluid. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 62(1), pp. 28-35. Lippincott Williams & Wilkins 10.1097/QAI.0b013e318274e2b0

von Wyl, Viktor; Yerly, Sabine; Böni, Jürg; Shah, Cyril; Cellerai, Cristina; Klimkait, Thomas; Battegay, Manuel; Bernasconi, Enos; Cavassini, Matthias; Furrer, Hansjakob; Hirschel, Bernard; Vernazza, Pietro L; Ledergerber, Bruno; Günthard, Huldrych F; Swiss HIV Cohort, Study (2012). Incidence of HIV-1 drug resistance among antiretroviral treatment-naive individuals starting modern therapy combinations. Clinical infectious diseases, 54(1), pp. 131-40. Cary, N.C.: Oxford University Press 10.1093/cid/cir728

Scherrer, Alexandra U.; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Furrer, Hansjakob; Calmy, Alexandra; Cavassini, Matthias; Elzi, Luigia; Vernazza, Pietro L.; Bernasconi, Enos; Ledergerber, Bruno; Günthard, Huldrych F.; Swiss HIV Cohort Study (SHCS), (2012). Long-lasting protection of activity of nucleoside reverse transcriptase inhibitors and protease inhibitors (PIs) by boosted PI containing regimens. PLoS ONE, 7(11), e50307. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0050307

Scherrer, Alexandra U.; Ledergerber, Bruno; von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Cellerai, Cristina; Furrer, Hansjakob; Calmy, Alexandra; Cavassini, Matthias; Elzi, Luigia; Vernazza, Pietro L.; Bernasconi, Enos; Günthard, Huldrych F.; Swiss HIV Cohort Study, (2012). Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients. PLoS ONE, 7(6), e37983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0037983

Schüpbach, Jörg; Bisset, Leslie R.; Gebhardt, Martin D.; Regenass, Stephan; Bürgisser, Philippe; Gorgievski, Meri; Klimkait, Thomas; Andreutti, Corinne; Martinetti, Gladys; Niederhauser, Christoph; Yerly, Sabine; Pfister, Stefan; Schultze, Detlev; Brandenberger, Marcel; Schöni-Affolter, Franziska; Scherrer, Alexandra U.; Günthard, Huldrych F.; Swiss HIV Cohort Study, (2012). Diagnostic performance of line-immunoassay based algorithms for incident HIV-1 infection. BMC infectious diseases, 12, p. 88. London: BioMed Central 10.1186/1471-2334-12-88

Schüpbach, Jörg; Bisset, Leslie R; Regenass, Stephan; Bürgisser, Philippe; Gorgievski, Meri; Steffen, Ingrid; Andreutti, Corinne; Martinetti, Gladys; Shah, Cyril; Yerly, Sabine; Klimkait, Thomas; Gebhardt, Martin; Schöni-Affolter, Franziska; Rickenbach, Martin; Keiser, O; Swiss HIV Cohort Study, (2011). High specificity of line-immunoassay based algorithms for recent HIV-1 infection independent of viral subtype and stage of disease. BMC infectious diseases, 11, p. 254. London: BioMed Central 10.1186/1471-2334-11-254

von Wyl, Viktor; Kouyos, Roger D; Yerly, Sabine; Böni, Jürg; Shah, Cyril; Bürgisser, Philippe; Klimkait, Thomas; Weber, Rainer; Hirschel, Bernard; Cavassini, Matthias; Staehelin, Cornelia; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Ledergerber, Bruno; Bonhoeffer, Sebastian; Günthard, Huldrych F; Swiss HIV Cohort Study, (2011). The role of migration and domestic transmission in the spread of HIV-1 non-B subtypes in Switzerland. Journal of infectious diseases, 204(7), pp. 1095-103. Cary, N.C.: Oxford University Press 10.1093/infdis/jir491

Scherrer, Alexandra U; Ledergerber, Bruno; von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Bürgisser, Philippe; Rauch, Andri; Hirschel, Bernard; Cavassini, Matthias; Elzi, Luigia; Vernazza, Pietro L; Bernasconi, Enos; Held, Leonhard; Günthard, Huldrych F; Swiss HIV Cohort, Study (2011). Improved virological outcome in White patients infected with HIV-1 non-B subtypes compared to subtype B. Clinical infectious diseases, 53(11), pp. 1143-52. Cary, N.C.: Oxford University Press 10.1093/cid/cir669

Kouyos, Roger D; von Wyl, Viktor; Yerly, Sabine; Böni, Jürg; Rieder, Philip; Joos, Beda; Taffé, Patrick; Shah, Cyril; Bürgisser, Philippe; Klimkait, Thomas; Weber, Rainer; Hirschel, Bernard; Cavassini, Matthias; Rauch, Andri; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Ledergerber, Bruno; Bonhoeffer, Sebastian; Günthard, Huldrych F; ... (2011). Ambiguous nucleotide calls from population-based sequencing of HIV-1 are a marker for viral diversity and the age of infection. Clinical infectious diseases, 52(4), pp. 532-9. Cary, N.C.: Oxford University Press 10.1093/cid/ciq164

Scherrer, Alexandra U; von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Bürgisser, Philippe; Garzoni, Christian; Hirschel, Bernard; Cavassini, Matthias; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Ledergerber, Bruno; Günthard, Huldrych F; Swiss HIV Cohort Study (SHCS), (2011). Viral suppression rates in salvage treatment with raltegravir improved with the administration of genotypic partially active or inactive nucleoside/tide reverse transcriptase inhibitors. Journal of acquired immune deficiency syndromes JAIDS, 57(1), pp. 24-31. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/QAI.0b013e318211925e

Fehr, Jan; Glass, Tracy R; Louvel, Séverine; Hamy, François; Hirsch, Hans H; von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Bürgisser, Philippe; Cavassini, Matthias; Fux, Christoph A; Hirschel, Bernard; Vernazza, Pietro; Martinetti, Gladys; Bernasconi, Enos; Günthard, Huldrych F; Battegay, Manuel; Bucher, Heiner C; Klimkait, Thomas and Swiss HIV Cohort Study, (2011). Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals--the Swiss HIV Cohort Study. Journal of translational medicine, 9, p. 14. London: BioMed Central 10.1186/1479-5876-9-14

Alizon, Samuel; von Wyl, Viktor; Stadler, Tanja; Kouyos, Roger D; Yerly, Sabine; Hirschel, Bernard; Böni, Jürg; Shah, Cyril; Klimkait, Thomas; Furrer, Hansjakob; Rauch, Andri; Vernazza, Pietro L; Bernasconi, Enos; Battegay, Manuel; Bürgisser, Philippe; Telenti, Amalio; Günthard, Huldrych F; Bonhoeffer, Sebastian; Swiss HIV Cohort Study, (2010). Phylogenetic approach reveals that virus genotype largely determines HIV set-point viral load. PLoS pathogens, 6(9), e1001123. San Francisco, Calif.: Public Library of Science 10.1371/journal.ppat.1001123

Kouyos, Roger D; von Wyl, Viktor; Yerly, Sabine; Böni, Jürg; Taffé, Patrick; Shah, Cyril; Bürgisser, Philippe; Klimkait, Thomas; Weber, Rainer; Hirschel, Bernard; Cavassini, Matthias; Furrer, Hansjakob; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Rickenbach, Martin; Ledergerber, Bruno; Bonhoeffer, Sebastian; Günthard, Huldrych F (2010). Molecular epidemiology reveals long-term changes in HIV type 1 subtype B transmission in Switzerland. Journal of infectious diseases, 201(10), pp. 1488-97. Cary, N.C.: The University of Chicago Press 10.1086/651951

Scherrer, Alexandra U; von Wyl, Viktor; Fux, Christof A; Opravil, Milos; Bucher, Heiner C; Fayet, Aurélie; Decosterd, Laurent A; Hirschel, Bernhard; Khanlari, Bettina; Yerly, Sabine; Klimkait, Thomas; Furrer, Hansjakob; Ledergerber, Bruno; Günthard, Huldrych F; Swiss HIV Cohort Study, (2010). Implementation of raltegravir in routine clinical practice: selection criteria for choosing this drug, virologic response rates, and characteristics of failures. Journal of acquired immune deficiency syndromes JAIDS, 53(4), pp. 464-71. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/QAI.0b013e3181bca4ec

Opravil, Milos; Klimkait, Thomas; Louvel, Severine; Wolf, Eva; Battegay, Manuel; Fux, Christoph A; Bernasconi, Enos; Vogel, Martin; Speck, Roberto; Weber, Rainer; Swiss HIV Cohort Study, (2010). Prior therapy influences the efficacy of lamivudine monotherapy in patients with lamivudine-resistant HIV-1 infection. Journal of acquired immune deficiency syndromes JAIDS, 54(1), pp. 51-8. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/QAI.0b013e3181bef889

von Wyl, Viktor; Yerly, Sabine; Bürgisser, Philippe; Klimkait, Thomas; Battegay, Manuel; Bernasconi, Enos; Cavassini, Matthias; Furrer, Hansjakob; Hirschel, Bernard; Vernazza, Pietro L; Francioli, Patrick; Bonhoeffer, Sebastian; Ledergerber, Bruno; Günthard Huldrych, F; Swiss HIV Cohort, Study (2009). Long-term trends of HIV type 1 drug resistance prevalence among antiretroviral treatment-experienced patients in Switzerland. Clinical infectious diseases, 48(7), pp. 979-87. Cary, N.C.: The University of Chicago Press 10.1086/597352

Weiser, Barbara; Philpott, Sean; Klimkait, Thomas; Burger, Harold; Kitchen, Christina; Bürgisser, Philippe; Gorgievski, Meri; Perrin, Luc; Piffaretti, Jean-Claude; Ledergerber, Bruno (2008). HIV-1 coreceptor usage and CXCR4-specific viral load predict clinical disease progression during combination antiretroviral therapy. AIDS, 22(4), pp. 469-79. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/QAD.0b013e3282f4196c

von Wyl, Viktor; Yerly, Sabine; Böni, Jürg; Bürgisser, Philippe; Klimkait, Thomas; Battegay, Manuel; Bernasconi, Enos; Cavassini, Matthias; Furrer, Hansjakob; Hirschel, Bernard; Vernazza, Pietro L; Rickenbach, Martin; Ledergerber, Bruno; Günthard, Huldrych F (2008). Factors associated with the emergence of K65R in patients with HIV-1 infection treated with combination antiretroviral therapy containing tenofovir. Clinical infectious diseases, 46(8), pp. 1299-309. Cary, N.C.: The University of Chicago Press 10.1086/528863

Liu, Songkai; Asparuhova, Maria; Brondani, Vincent; Ziekau, Ingrid; Klimkait, Thomas; Schümperli, Daniel (2004). Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin A. Nucleic acids research, 32(12), pp. 3752-3759. Oxford University Press 10.1093/nar/gkh715

Hirsch, Hans H.; Mohaupt, Markus; Klimkait, Thomas (2001). Prospective Monitoring of BK Virus Load after Discontinuing Sirolimus Treatment in a Renal Transplant Patient with BK Virus Nephropathy. Journal of infectious diseases, 184(11), pp. 1494-1495. The University of Chicago Press 10.1086/324425

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