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Allegritti, Elena; Giansanti, Luisa; Bordon, Gregor; Maggi, Maria Anna; Luciani, Paola; Aleandri, Simone (2024). Unlocking new dimensions in long-acting injectables using lipid mesophase-based beads. Journal of colloid and interface science, 664, pp. 1031-1041. Elsevier 10.1016/j.jcis.2024.03.067
Eugster, Remo; Ganguin, Aymar Abel; Seidi, Amirmohammad; Aleandri, Simone; Luciani, Paola (2024). 3D printing injectable microbeads using a composite liposomal ink for local treatment of peritoneal diseases. Drug delivery and translational research, 14(6), pp. 1567-1581. Springer 10.1007/s13346-023-01472-y
Dzhumashev, Dzhangar; Anton-Joseph, Stenija; Morel, Victoria J; Timpanaro, Andrea; Bordon, Gregor; Piccand, Caroline; Aleandri, Simone; Luciani, Paola; Rössler, Jochen; Bernasconi, Michele (2024). Rapid liposomal formulation for nucleolin targeting to rhabdomyosarcoma cells. European journal of pharmaceutics and biopharmaceutics, 194, pp. 49-61. Elsevier 10.1016/j.ejpb.2023.11.020
Arenas Hoyos, Isabel; Helmer, Anja; Yerly, Anaïs; Lese, Ioana; Hirsiger, Stefanie; Zhang, Lei; Casoni, Daniela; Garcia, Luisana; Petrucci, Mariafrancesca; Hammer, Sabine E; Duckova, Tereza; Banz, Yara; Montani, Matteo; Constantinescu, Mihai; Vögelin, Esther; Bordon, Gregor; Aleandri, Simone; Prost, Jean-Christophe; Taddeo, Adriano; Luciani, Paola; ... (2024). A local drug delivery system prolongs graft survival by dampening T cell infiltration and neutrophil extracellular trap formation in vascularized composite allografts. Frontiers in immunology, 15(1387945) Frontiers Research Foundation 10.3389/fimmu.2024.1387945
Gazzi, Rafaela; Gelli, Rita; Aleandri, Simone; Carone, Marianna; Luciani, Paola (2024). Bioinspired and bioderived nanomedicine for inflammatory bowel disease. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 16(4), e1986. Wiley 10.1002/wnan.1986
Ganguin, Aymar Abel; Skorup, Ivo; Streb, Sebastian; Othman, Alaa; Luciani, Paola (2023). Formation and Investigation of Cell-Derived Nanovesicles as Potential Therapeutics Against Chronic Liver Disease. Advanced healthcare materials, 12(30), e2300811. Wiley 10.1002/adhm.202300811
Bordon, Gregor; Berenbaum, Francis; Distler, Oliver; Luciani, Paola (2023). Harnessing the multifunctionality of lipid-based drug delivery systems for the local treatment of osteoarthritis. Biomedicine & pharmacotherapy, 168(115819), p. 115819. Elsevier 10.1016/j.biopha.2023.115819
Zimmermann, Christoph M; Deßloch, Leonie; Jürgens, David C; Luciani, Paola; Merkel, Olivia M (2023). Evaluation of the effects of storage conditions on spray-dried siRNA-LNPs before and after subsequent drying. European journal of pharmaceutics and biopharmaceutics, 193, pp. 218-226. Elsevier 10.1016/j.ejpb.2023.11.007
Bordon, Gregor; Ramakrishna, Shivaprakash N; Edalat, Sam G; Eugster, Remo; Arcifa, Andrea; Vermathen, Martina; Aleandri, Simone; Bertoncelj, Mojca Frank; Furrer, Julien; Vermathen, Peter; Isa, Lucio; Crockett, Rowena; Distler, Oliver; Luciani, Paola (2023). Liposomal aggregates sustain the release of rapamycin and protect cartilage from friction. Journal of Colloid and Interface Science, 650(Pt B), pp. 1659-1670. Elsevier 10.1016/j.jcis.2023.07.087
Skorup, Ivo; Valentino, Gina; Aleandri, Simone; Gelli, Rita; Ganguin, Aymar Abel; Felli, Eric; Selicean, Sonia Emilia; Marxer, Rosanne Angela; Teworte, Sarah; Lucić, Ana; Gracia-Sancho, Jordi; Berzigotti, Annalisa; Ridi, Francesca; Luciani, Paola (2023). Polyenylphosphatidylcholines as bioactive excipient in tablets for the treatment of liver fibrosis. International journal of pharmaceutics, 646, p. 123473. Elsevier 10.1016/j.ijpharm.2023.123473
Teworte, Sarah; Aleandri, Simone; Weber, Jessica; Carone, Marianna; Luciani, Paola (2023). Mucoadhesive 3D printed vaginal ovules to treat endometriosis and fibrotic uterine diseases. European journal of pharmaceutical sciences, 188, p. 106501. Elsevier 10.1016/j.ejps.2023.106501
Carone, Marianna; Spalinger, Marianne R; Gaultney, Robert A; Mezzenga, Raffaele; Hlavacková, Kristyna; Mookhoek, Aart; Krebs, Philippe; Rogler, Gerhard; Luciani, Paola; Aleandri, Simone (2023). Temperature-triggered in situ forming lipid mesophase gel for local treatment of ulcerative colitis. Nature Communications, 14(1), p. 3489. Springer Nature 10.1038/s41467-023-39013-3
Spera, Irene; Cousin, Nikola; Ries, Miriam; Kedracka, Anna; Castillo, Alina; Aleandri, Simone; Vladymyrov, Mykhailo; Mapunda, Josephine A; Engelhardt, Britta; Luciani, Paola; Detmar, Michael; Proulx, Steven T (2023). Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves. EBioMedicine, 91(104558), p. 104558. Elsevier 10.1016/j.ebiom.2023.104558
Zivko, Cristina; Witt, Finja; Koeberle, Andreas; Fuhrmann, Gregor; Luciani, Paola (2023). Formulating elafibranor and obeticholic acid with phospholipids decreases drug-induced association of SPARC to extracellular vesicles from LX-2 human hepatic stellate cells. European journal of pharmaceutics and biopharmaceutics, 182, pp. 32-40. Elsevier 10.1016/j.ejpb.2022.11.025
Teworte, Sarah; Luciani, Paola (2023). Endometriosis, the Silent Disease: Molecular Targets, Active Principles, and Drug Delivery Systems. Helvetica chimica acta, 106(1) Verlag Helvetica Chimica Acta 10.1002/hlca.202200132
Aleandri, Simone; Rahnfeld, Lisa; Chatzikleanthous, Despo; Bergadano, Alessandra; Bühr, Claudia; Detotto, Carlotta; Fuochi, Sara; Weber-Wilk, Kevin; Schürch, Stefan; van Hoogevest, Peter; Luciani, Paola (2022). Development and in vivo validation of phospholipid-based depots for the sustained release of bupivacaine. European journal of pharmaceutics and biopharmaceutics, 181, pp. 300-309. Elsevier 10.1016/j.ejpb.2022.11.019
Zimmermann, Christoph M.; Baldassi, Domizia; Chan, Karen; Adams, Nathan B.P.; Neumann, Alina; Porras-Gonzalez, Diana Leidy; Wei, Xin; Kneidinger, Nikolaus; Stoleriu, Mircea Gabriel; Burgstaller, Gerald; Witzigmann, Dominik; Luciani, Paola; Merkel, Olivia M. (2022). Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery. Journal of controlled release, 351, pp. 137-150. Elsevier 10.1016/j.jconrel.2022.09.021
Zivko, Cristina; Fuhrmann, Kathrin; Fuhrmann, Gregor; Luciani, Paola (2022). Tracking matricellular protein SPARC in extracellular vesicles as a non-destructive method to evaluate lipid-based antifibrotic treatments. Communications biology, 5(1), p. 1155. Springer Nature 10.1038/s42003-022-04123-z
Elzenaty, Oumar; Luciani, Paola; Aleandri, Simone (2022). A lipidic mesophase with tunable release properties for the local delivery of macromolecules: the apoferritin nanocage, a case study. Journal of materials chemistry B, 10(20), pp. 3876-3885. Royal Society of Chemistry 10.1039/d2tb00403h
Weber, Florian; C. Ivan, Daniela; Proulx, Steven T.; Locatelli, Giuseppe; Aleandri, Simone; Luciani, Paola (2021). Beyond Trial and Error: A Systematic Development of Liposomes Targeting Primary Macrophages. Advanced nanoBiomed research, 1(3), p. 2000098. Wiley 10.1002/anbr.202000098
Cardinell, Kirsten; Gupta, Neeru; Koivisto, Bryan D.; Kumaradas, J. Carl; Zhou, Xun; Irving, Hyacinth; Luciani, Paola; Yücel, Yeni H. (2021). A novel photoacoustic-fluorescent contrast agent for quantitative imaging of lymphatic drainage. Photoacoustics, 21, p. 100239. Elsevier 10.1016/j.pacs.2021.100239
Weber, Florian; Casalini, Tommaso; Valentino, Gina; Brülisauer, Lorine; Andreas, Nico; Koeberle, Andreas; Kamradt, Thomas; Contini, Alessandro; Luciani, Paola (2021). Targeting transdifferentiated hepatic stellate cells and monitoring the hepatic fibrogenic process by means of IGF2R-specific peptides designed in silico. Journal of materials chemistry B, 9(8), pp. 2092-2106. Royal Society of Chemistry 10.1039/D0TB02372H
Alijaj, Nagjie; Moutel, Sandrine; Gouveia, Zelia L; Gray, Maxim; Roveri, Maurizio; Dzhumashev, Dzhangar; Weber, Florian; Meier, Gianmarco; Luciani, Paola; Rössler, Jochen K.; Schäfer, Beat W; Perez, Franck; Bernasconi, Michele (2020). Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma. Cancers, 12(11) MDPI AG 10.3390/cancers12113313
Rahnfeld, Lisa; Luciani, Paola (2020). Injectable Lipid-Based Depot Formulations: Where Do We Stand? Pharmaceutics, 12(6), p. 567. MDPI 10.3390/pharmaceutics12060567
Weber, Florian; Rahnfeld, Lisa; Luciani, Paola (2020). Analytical profiling and stability evaluation of liposomal drug delivery systems: a rapid UHPLC-CAD-based approach for phospholipids in research and quality control. Talanta, 220, p. 121320. Elsevier 10.1016/j.talanta.2020.121320
Zivko, Cristina; Fuhrmann, Gregor; Luciani, Paola (2020). Liver-derived extracellular vesicles: A cell by cell overview to isolation and characterization practices. Biochimica et biophysica acta (BBA) - general subjects, 1865(4), p. 129559. Elsevier 10.1016/j.bbagen.2020.129559
Valentino, Gina; Zivko, Cristina; Weber, Florian; Brülisauer, Lorine; Luciani, Paola (2019). Synergy of Phospholipid—Drug Formulations Significantly Deactivates Profibrogenic Human Hepatic Stellate Cells. Pharmaceutics, 11(12) MDPI 10.3390/pharmaceutics11120676
Sutter, Damian; Dzhonova, Dzhuliya V.; Prost, Jean-Christophe; Bovet, Cedric; Banz, Yara; Rahnfeld, Lisa; Leroux, Jean-Christophe; Rieben, Robert; Vögelin, Esther; Plock, Jan A.; Luciani, Paola; Taddeo, Adriano; Schnider, Jonas T. (2019). Delivery of Rapamycin Using In Situ Forming Implants Promotes Immunoregulation and Vascularized Composite Allograft Survival. Scientific reports, 9(1), p. 9269. Springer Nature 10.1038/s41598-019-45759-y
Chong, Chloé; Scholkmann, Felix; Bachmann, Samia B; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Proulx, Steven T (2016). In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging. Scientific Reports, 6, p. 22930. Nature Publishing Group 10.1038/srep22930
Karaman, Sinem; Buschle, Dorina; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Proulx, Steven T (2015). Decline of lymphatic vessel density and function in murine skin during aging. Angiogenesis, 18(4), pp. 489-498. Springer Netherlands 10.1007/s10456-015-9479-0
Blum, Katrin S; Karaman, Sinem; Proulx, Steven T; Ochsenbein, Alexandra M; Luciani, Paola; Leroux, Jean-Christophe; Wolfrum, Christian; Detmar, Michael (2014). Chronic high-fat diet impairs collecting lymphatic vessel function in mice. PLoS ONE, 9(4), e94713. Public Library of Science 10.1371/journal.pone.0094713
Proulx, Steven T; Luciani, Paola; Dieterich, Lothar C; Karaman, Sinem; Leroux, Jean-Christophe; Detmar, Michael (2013). Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery. Journal of controlled release, 172(2), pp. 550-557. Elsevier 10.1016/j.jconrel.2013.04.027
Proulx, Steven T; Luciani, Paola; Christiansen, Ailsa; Karaman, Sinem; Blum, Katrin S; Rinderknecht, Matthias; Leroux, Jean-Christophe; Detmar, Michael (2013). Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis. Biomaterials, 34(21), pp. 5128-5137. Elsevier 10.1016/j.biomaterials.2013.03.034
Proulx, Steven T; Luciani, Paola; Alitalo, Annamari; Mumprecht, Viviane; Christiansen, Ailsa J; Huggenberger, Reto; Leroux, Jean-Christophe; Detmar, Michael (2013). Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo. Angiogenesis, 16(3), pp. 525-540. Springer Netherlands 10.1007/s10456-013-9332-2
Blum, Katrin S; Proulx, Steven T; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael (2013). Dynamics of lymphatic regeneration and flow patterns after lymph node dissection. Breast cancer research and treatment, 139(1), pp. 81-86. Springer 10.1007/s10549-013-2537-7
Duong, Tam; Proulx, Steven T; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Koopman, Peter; Francois, Mathias (2012). Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer research, 72(12), pp. 3105-3114. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-4026
Proulx, Steven T; Luciani, Paola; Derzsi, Stefanie; Rinderknecht, Matthias; Mumprecht, Viviane; Leroux, Jean-Christophe; Detmar, Michael (2010). Quantitative imaging of lymphatic function with liposomal indocyanine green. Cancer research, 70(18), pp. 7053-7062. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-0271
Benvenuti, Susanna; Saccardi, Riccardo; Luciani, Paola; Urbani, Serena; Deledda, Cristiana; Cellai, Ilaria; Francini, Fabio; Squecco, Roberta; Rosati, Fabiana; Danza, Giovanna; Gelmini, Stefania; Greeve, Isabell; Rossi, Matteo; Maggi, Roberto; Serio, Mario; Peri, Alessandro (2006). Neuronal differentiation of human mesenchymal stem cells: changes in the expression of the Alzheimer's disease-related gene seladin-1. Experimental cell research, 312(13), pp. 2592-604. San Diego, Calif.: Elsevier 10.1016/j.yexcr.2006.04.016
