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Brugger, Silvio; Troxler, Lukas; Rüfenacht, Susanne; Frey, Pascal Marcel; Morand, Brigitte; Geyer, Rudolf; Mühlemann, Kathrin; Höck, Stefan; Thormann, Wolfgang; Furrer, Julien; Christen, Stephan; Hilty, Markus (2016). Polysaccharide capsule composition of pneumococcal serotype 19A subtypes: Unaltered among subtypes and independent of the nutritional environment. Infection and immunity, 84(11), pp. 3152-3160. American Society for Microbiology 10.1128/IAI.00474-16
Jayadev Kamat, Pranitha; Vandenberghe, Stijn; Christen, Stephan; Bongoni, Anjan; Meier, Bernhard; Rieben, Robert; Khattab, Ahmed Aziz (2016). Dexrazoxane Shows No Protective Effect in the Acute Phase of Reperfusion during Myocardial Infarction in Pigs. PLoS ONE, 11(12), e0168541. Public Library of Science 10.1371/journal.pone.0168541
Coutinho, Leonam G; Christen, Stephan; Bellac, Caroline L; Fontes, Fabrícia; de Souza, Fladjule; Grandgirard, Denis; Leib, Stephen; Agnez-Lima, Lucymara F (2014). The kynurenine pathway is involved in bacterial meningitis. Journal of neuroinflammation, 11(169), p. 169. BioMed Central 10.1186/s12974-014-0169-4
Autheman, Delphine; Wyder, Marianne; Popoff, Michel; D'Herde, Katharina; Christen, Stephan; Posthaus, Horst (2013). Clostridium perfringens beta-toxin induces necrostatin-inhibitable, calpain-dependent necrosis in primary porcine endothelial cells. PLoS ONE, 8(5), e64644. Public Library of Science 10.1371/journal.pone.0064644
Tveden-Nyborg, Pernille; Vogt, Lucile; Schjoldager, Janne G.; Jeannet, Natalie; Hasselholt, Stine; Paidi, Maya D.; Lykkesfeldt, Jens; Christen, Stephan (2012). Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs. PLoS ONE, 7(10), e48488. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0048488
Autheman, Delphine; Sheldon, R Ann; Chaudhuri, Nondini; von Arx, Sebastian; Siegenthaler, Corinne; Ferriero, Donna M; Christen, Stephan (2012). Glutathione peroxidase overexpression causes aberrant ERK activation in neonatal mouse cortex after hypoxic preconditioning. Pediatric research, 72(6), pp. 568-75. New York, N.Y.: Nature Publishing Group 10.1038/pr.2012.124
Ortmann, Jana; Veit, Martha; Zingg, Sandra; Di Santo, Stefano; Traupe, Tobias; Yang, Zijiang; Völzmann, Jan; Dubey, Raghvendra K; Christen, Stephan; Baumgartner, Iris (2011). Estrogen receptor- but not - or GPER inhibits high glucose-induced human VSMC proliferation: potential role of ROS and ERK. Journal of clinical endocrinology and metabolism, 96(1), pp. 220-8. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2010-0943
Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007
Bellac, Caroline L.; Coimbra, Roney S.; Christen, Stephan; Leib, Stephen L. (2010). Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis. Journal of neuropathology and experimental neurology, 69(11), pp. 1096-1104. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e3181f7e7e9
Znoj, Hansjörg; Messerli-Burgy, Nadine; Tschopp, Simone; Weber, Rainer; Christen, Lisanne; Christen, Stephan; Grawe, Klaus (2010). Psychotherapeutic Process of Cognitive-Behavioral Intervention in HIV-Infected Persons: Results from a Controlled, Randomized Prospective Clinical Trial. Psychotherapy research, 20(2), pp. 203-213. Abingdon, UK: Routledge 10.1080/10503300903246663
Sheldon, R Ann; Christen, Stephan; Ferriero, Donna M (2008). Genetic and pharmacologic manipulation of oxidative stress after neonatal hypoxia-ischemia. International journal of developmental neuroscience, 26(1), pp. 87-92. Kidlington, UK: Elsevier Science 10.1016/j.ijdevneu.2007.08.010
Sury, Matthias D.; Agarinis, Claudia; Widmer, Hans-Rudolf; Leib, Stephen L.; Christen, Stephan (2008). JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 32(1), pp. 142-150. Amsterdam: Elsevier 10.1016/J.nbd.2008.07.006
Ren, Hao; Leib, Stephen L.; Ferriero, Donna M; Täuber, Martin G.; Christen, Stephan (2007). Induction of haem oxygenase-1 causes cortical non-haem iron increase in experimental pneumococcal meningitis: evidence that concomitant ferritin up-regulation prevents iron-induced oxidative damage. Journal of neurochemistry, 100(2), pp. 532-544. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2006.04230.x
Christen, Stephan; Cattin, Isabelle; Knight, Iona; Winyard, Paul G; Blum, Jürg W; Elsasser, Theodore H (2007). Plasma S-nitrosothiol status in neonatal calves: ontogenetic associations with tissue-specific S-nitrosylation and nitric oxide synthase. Experimental biology and medicine, 232(2), pp. 309-22. Maywood, N.J.: Society for Experimental Biology & Medicine
Lykkesfeldt, Jens; Trueba, Gilberto Perez; Poulsen, Henrik E; Christen, Stephan (2007). Vitamin C deficiency in weanling guinea pigs: differential expression of oxidative stress and DNA repair in liver and brain. British journal of nutrition, 98(6), pp. 1116-9. Cambridge: Cambridge University Press 10.1017/S0007114507787457
Lykkesfeldt, Jens; Morgan, Evan; Christen, Stephan; Skovgaard, Lene Theil; Moos, Torben (2007). Oxidative stress and damage in liver, but not in brain, of Fischer 344 rats subjected to dietary iron supplementation with lipid-soluble [(3,5,5-trimethylhexanoyl)ferrocene]. Journal of biochemical and molecular toxicology, 21(3), pp. 145-55. New York, N.Y.: Wiley & Sons 10.1002/jbt.20170
Sheldon, R Ann; Aminoff, Alexandra; Lee, Christina L; Christen, Stephan; Ferriero, Donna M (2007). Hypoxic preconditioning reverses protection after neonatal hypoxia-ischemia in glutathione peroxidase transgenic murine brain. Pediatric research, 61(6), pp. 666-70. New York, N.Y.: Nature Publishing Group 10.1203/pdr.0b013e318053664c
Reiter, Elke; Jiang, Qing; Christen, Stephan (2007). Anti-inflammatory properties of alpha- and gamma-tocopherol. Molecular aspects of medicine, 28(5-6), pp. 668-91. Amsterdam: Elsevier 10.1016/j.mam.2007.01.003
Sury, Matthias D; Frese-Schaper, Manuela; Mühlemann, Miranda K; Schulthess, Fabienne T; Blasig, Ingolf E; Täuber, Martin G; Shaw, Sidney G; Christen, Stephan (2006). Evidence that N-acetylcysteine inhibits TNF-alpha-induced cerebrovascular endothelin-1 upregulation via inhibition of mitogen- and stress-activated protein kinase. Free radical biology & medicine, 41(9), pp. 1372-83. San Diego, Calif.: Elsevier 10.1016/j.freeradbiomed.2006.07.016
Bellac, Caroline L.; Coimbra, Roney S.; Christen, Stephan; Leib, Stephen L. (2006). Pneumococcal meningitis causes accumulation of neurotoxic kynurenine metabolites in brain regions prone to injury. Neurobiology of disease, 24(2), pp. 395-402. Amsterdam: Elsevier 10.1016/j.nbd.2006.07.014
Schaper, Manuela; Leib, Stephen; Meli, Damian N; Brandes, Ralf P; Täuber, Martin G.; Christen, Stephan (2003). Differential effect of p47phox and gp91phox deficiency on the course of Pneumococcal Meningitis. Infection and immunity, 71(7), pp. 4087-4092. American Society for Microbiology 10.1128/IAI.71.7.4087-4092.2003
Ghielmetti, Marco; Ren, Hao; Leib, Stephen; Täuber, Martin G.; Christen, Stephan (2003). Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis. Brain research, 976(2), pp. 139-148. Elsevier 10.1016/S0006-8993(03)02557-5
Meli, Damian N.; Christen, Stephan; Leib, Stephen L. (2003). Matrix metalloproteinase-9 in pneumococcal meningitis: activation via an oxidative pathway. Journal of infectious diseases, 187(9), pp. 1411-1415. Cary, N.C.: The University of Chicago Press 10.1086/374644
Schaper, Manuela; Gergely, Suzanne; Lykkesfeldt, Jens; Zbären, Jakob; Leib, Stephen L.; Täuber, Martin G.; Christen, Stephan (2002). Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis. Journal of neuropathology and experimental neurology, 61(7), pp. 605-13. Hagerstown, Md.: Lippincott Williams & Wilkins
Meli, Damian N.; Christen, Stephan; Leib, Stephen L.; Täuber, Martin G. (2002). Current concepts in the pathogenesis of meningitis caused by Streptococcus pneumoniae. Current opinion in infectious diseases, 15(3), pp. 253-357. Hagerstown, Md.: Wolters Kluwer Lippincott Williams & Wilkins 10.1097/00001432-200206000-00007
Pfister, H.; Remer, K. A.; Brcic, Marija; Fatzer, R.; Christen, Stephan; Leib, Stephen L.; Jungi, Thomas W. (2002). Inducible nitric oxide synthase and nitrotyrosine in listeric encephalitis: a cross-species study in ruminants. Veterinary pathology, 39(2), pp. 190-199. Middleton, Wis.: American College of Veterinary Pathologists 10.1354/vp.39-2-190
Christen, Stephan; Schaper, Manuela; Lykkesfeldt, Jens; Siegenthaler, Corinne; Bifrare, Yoeng-Delphine; Banic, Staša; Leib, Stephen L.; Täuber, Martin G. (2001). Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment. Free radical biology & medicine, 31(6), pp. 754-762. San Diego, Calif.: Elsevier 10.1016/S0891-5849(01)00642-6
Christen, Stephan; Bifrare, Yeong-Delphine; Siegenthaler, Corinne; Leib, Stephen L.; Täuber, Martin G. (2001). Marked elevation in cortical urate and xanthine oxidoreductase activity in experimental bacterial meningitis. Brain research, 900(2), pp. 244-251. Amsterdam: Elsevier 10.1016/S0006-8993(01)02311-3