Reubi, Jean Claude

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Journal Article

Reubi, Jean Claude; Fourmy, Daniel; Cordomi, Arnau; Tikhonova, Irina G; Gigoux, Véronique (2020). GIP receptor: Expression in neuroendocrine tumours, internalization, signalling from endosomes and structure-function relationship studies. Peptides, 125, p. 170229. Elsevier 10.1016/j.peptides.2019.170229

Antwi, Kwadwo; Nicolas, Guillaume; Fani, Melpomeni; Heye, Tobias; Pattou, Francois; Grossman, Ashley; Chanson, Philippe; Reubi, Jean Claude; Perren, Aurel; Gloor, Beat; Vogt, Deborah R; Wild, Damian; Christ, Emanuel (2019). 68Ga-exendin-4 PET/CT detects insulinomas in patients with endogenous hyperinsulinemic hypoglycemia in MEN-1. The journal of clinical endocrinology and metabolism, 104(12), pp. 5843-5852. Oxford University Press 10.1210/jc.2018-02754

Kaloudi, Aikaterini; Lymperis, Emmanouil; Kanellopoulos, Panagiotis; Waser, Beatrice; de Jong, Marion; Krenning, Eric P; Reubi, Jean Claude; Nock, Berthold A; Maina, Theodosia (2019). Localization of 99mTc-GRP Analogs in GRPR-Expressing Tumors: Effects of Peptide Length and Neprilysin Inhibition on Biological Responses. Pharmaceuticals, 12(1) MDPI 10.3390/ph12010042

Abiraj, Keelara; Ursillo, Samer; Tamma, Maria Luisa; Rylova, Svetlana N; Waser, Beatrice; Constable, Edwin C; Fani, Melpomeni; Nicolas, Guillaume P; Reubi, Jean Claude; Maecke, Helmut R (2018). The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist. EJNMMI research, 8(1), p. 75. Springer 10.1186/s13550-018-0428-y

Nicolas, Guillaume P; Beykan, Seval; Bouterfa, Hakim; Kaufmann, Jens; Bauman, Andreas; Lassmann, Michael; Reubi, Jean Claude; Rivier, Jean E F; Maecke, Helmut R; Fani, Melpomeni; Wild, Damian (2018). Safety, Biodistribution, and Radiation Dosimetry of Ga-OPS202 in Patients with Gastroenteropancreatic Neuroendocrine Tumors: A Prospective Phase I Imaging Study. Journal of nuclear medicine, 59(6), pp. 909-914. Society of Nuclear Medicine 10.2967/jnumed.117.199737

Wan, Ming Young Simon; Endozo, Raymond; Michopoulou, Sofia; Shortman, Robert; Rodriguez-Justo, Manuel; Menezes, Leon; Yusuf, Syed; Richards, Toby; Wild, Damian; Waser, Beatrice; Reubi, Jean Claude; Groves, Ashley (2017). PETCT Imaging of Unstable Carotid Plaque with Ga-68 labelled Somatostatin Receptor Ligand. Journal of nuclear medicine, 58(5), pp. 774-780. Society of Nuclear Medicine 10.2967/jnumed.116.181438

Popp, Ilinca; Del Pozzo, Luigi; Waser, Beatrice; Reubi, Jean Claude; Meyer, Philipp T; Maecke, Helmut R; Gourni, Eleni (2017). Approaches to improve metabolic stability of a statine-based GRP receptor antagonist. Nuclear medicine and biology, 45, pp. 22-29. Elsevier 10.1016/j.nucmedbio.2016.11.004

Reubi, Jean Claude; Waser, Beatrice; Maecke, Helmut R; Rivier, Jean E (2016). HIGHLY INCREASED 125I-JR11 ANTAGONIST BINDING IN VITRO REVEALS NOVEL INDICATIONS FOR SST2 TARGETING IN HUMAN CANCERS. Journal of nuclear medicine, 58(2), pp. 300-306. Society of Nuclear Medicine 10.2967/jnumed.116.177733

Rylova, Svetlana N; Waser, Beatrice; Del Pozzo, Luigi; Tönnesmann, Roswitha; Mansi, Rosalba; Meyer, Philipp T; Reubi, Jean Claude; Maecke, Helmut R (2016). Approaches to Improve the Pharmacokinetics of Radiolabeled Glucagon-Like Peptide-1 Receptor Ligands Using Antagonistic Tracers. Journal of nuclear medicine, 57(8), pp. 1282-1288. Society of Nuclear Medicine 10.2967/jnumed.115.168948

Antwi, Kwadwo; Fani, Melpomeni; Nicolas, Guillaume; Rottenburger, Christof; Heye, Tobias; Reubi, Jean Claude; Gloor, Beat; Christ, Emanuel; Wild, Damian (2015). Localization of Hidden Insulinomas with 68Ga-DOTA-Exendin-4 PET/CT: A Pilot Study. Journal of nuclear medicine, 56(7), pp. 1075-1078. Society of Nuclear Medicine 10.2967/jnumed.115.157768

Kolenc Peitl, Petra; Tamma, MariaLuisa; Kroselj, Marko; Braun, Friederike; Waser, Beatrice; Reubi, Jean Claude; Sollner Dolenc, Marija; Maecke, Helmut R; Mansi, Rosalba (2015). Stereochemistry of Amino Acid Spacers Determines the Pharmacokinetics of (111)In-DOTA-Minigastrin Analogues for Targeting the CCK2/Gastrin Receptor. Bioconjugate chemistry, 26(6), pp. 1113-1119. American Chemical Society 10.1021/acs.bioconjchem.5b00187

Christ, Emanuel; Wild, Damian; Antwi, Kwadwo; Waser, Beatrice; Fani, Melpomeni; Schwanda, Stefanie; Heye, Tobias; Schmid, Christoph; Baer, Hans Ulrich; Perren, Aurel; Reubi, Jean Claude (2015). Preoperative localization of adult nesidioblastosis using (68)Ga-DOTA-exendin-4-PET/CT. Endocrine, 50(3), pp. 821-823. Springer 10.1007/s12020-015-0633-7

Reubi, Jean Claude; Waser, Beatrice (2015). Triple-peptide receptor targeting in vitro allows detection of all tested gut and bronchial NETs. Journal of nuclear medicine, 56(4), pp. 613-615. Society of Nuclear Medicine 10.2967/jnumed.114.153189

Mansi, Rosalba; Abiraj, Keelara; Wang, Xuejuan; Tamma, Maria Luisa; Gourni, Eleni; Cescato, Renzo; Berndt, Sandra; Reubi, Jean Claude; Maecke, Helmut R (2015). Evaluation of three different families of bombesin receptor radioantagonists for targeted imaging and therapy of gastrin releasing peptide receptor (GRP-R) positive tumors. Journal of medicinal chemistry, 58(2), pp. 682-691. American Chemical Society 10.1021/jm5012066

Körner Jachertz, Meike; Waser, Beatrice; Strobel, Oliver; Büchler, Markus; Reubi, Jean Claude (2015). Neurotensin receptors in pancreatic ductal carcinomas. EJNMMI research, 5(17), p. 17. Springer 10.1186/s13550-015-0094-2

Körner Jachertz, Meike; Waser, Beatrice; Reubi, Jean Claude (2015). Does somatostatin or gastric inhibitory peptide receptor expression correlate with tumor grade and stage in gut neuroendocrine tumors? Neuroendocrinology, 101(1), pp. 45-57. Karger 10.1159/000371804

Mikkola, Kirsi; Kirsi, Mikkola; Yim, Cheng-Bin; Cheng-Bin, Yim; Fagerholm, Veronica; Veronica, Fagerholm; Ishizu, Tamiko; Tamiko, Ishizu; Elomaa, Viki-Veikko; Viki-Veikko, Elomaa; Rajander, Johan; Johan, Rajander; Jurttila, Jori; Jori, Jurttila; Saanijoki, Tiina; Tiina, Saanijoki; Tolvanen, Tuula; Tuula, Tolvanen; Tirri, Marko; Marko, Tirri; ... (2014). 64Cu- and 68Ga-labelled [Nle(14),Lys(40)(Ahx-NODAGA)NH2]-exendin-4 for pancreatic beta cell imaging in rats. Molecular imaging and biology, 16(2), pp. 255-263. Springer 10.1007/s11307-013-0691-2

Körner, Meike; Christ, Emanuel; Wild, Damian; Reubi, Jean Claude (2012). Glucagon-like peptide-1 receptor overexpression in cancer and its impact on clinical applications. Frontiers in endocrinology, 3, p. 158. Lausanne: Frontiers Research Foundation 10.3389/fendo.2012.00158

Wild, Damian; Christ, Emanuel; Caplin, Martyn E; Kurzawinski, Tom R; Forrer, Flavio; Brändle, Michael; Seufert, Jochen; Weber, Wolfgang A; Bomanji, Jamshed; Perren, Aurel; Ell, Peter J; Reubi, Jean Claude (2011). Glucagon-like peptide-1 versus somatostatin receptor targeting reveals 2 distinct forms of malignant insulinomas. Journal of nuclear medicine, 52(7), pp. 1073-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.085142

Fourmy, Daniel; Gigoux, Véronique; Reubi, Jean Claude (2011). Gastrin in gastrointestinal diseases. Gastroenterology, 141(3), 814-818.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2011.07.006

Reubi, Jean Claude; Erchegyi, Judit; Cescato, Renzo; Waser, Beatrice; Rivier, Jean E (2010). Switch from antagonist to agonist after addition of a DOTA chelator to a somatostatin analog. European journal of nuclear medicine and molecular imaging, 37(8), pp. 1551-8. Berlin: Springer-Verlag 10.1007/s00259-010-1445-x

Grace, Christy Rani R; Erchegyi, Judit; Reubi, Jean Claude; Rivier, Jean E; Riek, Roland (2008). Three-dimensional consensus structure of sst2-selective somatostatin (SRIF) antagonists by NMR. Biopolymers, 89(12), pp. 1077-87. Hoboken, N.J.: John Wiley & Sons, Inc. 10.1002/bip.21060

Körner, Meike; Reubi, Jean Claude (2008). Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors. Journal of neuropathology and experimental neurology, 67(8), pp. 741-9. Hagerstown, Md.: Lippincott Williams & Wilkins

Erchegyi, Judit; Grace, Christy Rani R; Samant, Manoj; Cescato, Renzo; Piccand, Veronique; Riek, Roland; Reubi, Jean Claude; Rivier, Jean E (2008). Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity. Journal of medicinal chemistry, 51(9), pp. 2668-75. Easton, Pa.: American Chemical Society 10.1021/jm701444y

Grace, Christy Rani R; Erchegyi, Judit; Samant, Manoj; Cescato, Renzo; Piccand, Veronique; Riek, Roland; Reubi, Jean Claude; Rivier, Jean E (2008). Ring size in octreotide amide modulates differently agonist versus antagonist binding affinity and selectivity. Journal of medicinal chemistry, 51(9), pp. 2676-81. Easton, Pa.: American Chemical Society 10.1021/jm701445q

Ginj, Mihaela; Zhang, Hanwen; Eisenwiener, Klaus-Peter; Wild, Damian; Schulz, Stefan; Rink, Hans; Cescato, Renzo; Reubi, Jean Claude; Maecke, Helmut R (2008). New pansomatostatin ligands and their chelated versions: affinity profile, agonist activity, internalization, and tumor targeting. Clinical cancer research, 14(7), pp. 2019-27. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-07-1687

D'Addona, Debora; Carotenuto, Alfonso; Novellino, Ettore; Piccand, Véronique; Reubi, Jean Claude; Di Cianni, Alessandra; Gori, Francesca; Papini, Anna Maria; Ginanneschi, Mauro (2008). Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships. Journal of medicinal chemistry, 51(3), pp. 512-20. Easton, Pa.: American Chemical Society 10.1021/jm070886i

Cescato, Renzo; Maina, Theodosia; Nock, Berthold; Nikolopoulou, Anastasia; Charalambidis, David; Piccand, Véronique; Reubi, Jean Claude (2008). Bombesin receptor antagonists may be preferable to agonists for tumor targeting. Journal of nuclear medicine, 49(2), pp. 318-26. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.107.045054

Gugger, Mathias; White, Richard; Song, Susan; Waser, Bea; Cescato, Renzo; Rivière, Pierre; Reubi, Jean Claude (2008). GPR87 is an overexpressed G-protein coupled receptor in squamous cell carcinoma of the lung. Disease markers, 24(1), pp. 41-50. Amsterdam: IOS Press 10.1155/2008/857474

Cescato, Renzo; Erchegyi, Judith; Waser, Beatrice; Piccand, Véronique; Maecke, Helmut R; Rivier, Jean E; Reubi, Jean Claude (2008). Design and in vitro characterization of highly sst2-selective somatostatin antagonists suitable for radiotargeting. Journal of medicinal chemistry, 51(13), pp. 4030-7. Easton, Pa.: American Chemical Society 10.1021/jm701618q

Waser, Beatrice; Eltschinger, Véronique; Linder, Karen; Nunn, Adrian; Reubi, Jean Claude (2007). Selective in vitro targeting of GRP and NMB receptors in human tumours with the new bombesin tracer 177Lu-AMBA. European journal of nuclear medicine and molecular imaging, 34(1), pp. 95-100. Berlin: Springer-Verlag 10.1007/s00259-006-0229-9

Fleischmann, Achim; Waser, Beatrice; Reubi, Jean Claude (2007). Overexpression of gastrin-releasing peptide receptors in tumor-associated blood vessels of human ovarian neoplasms. Cellular oncology, 29(5), pp. 421-33. Amsterdam: IOS Press

Reubi, Jean Claude (2007). Peptide receptor expression in GEP-NET. Virchows Archiv, 451 Suppl 1, S47-50. Berlin: Springer-Verlag 10.1007/s00428-007-0443-2

Hayes, Gregory M; Carrigan, Patricia E; Dong, Maoqing; Reubi, Jean Claude; Miller, Laurence J (2007). A novel secretin receptor splice variant potentially useful for early diagnosis of pancreatic carcinoma. Gastroenterology, 133(3), pp. 853-61. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2007.06.013

Feytens, Debby; Cescato, Renzo; Reubi, Jean Claude; Tourwé, Dirk (2007). New sst4/5-selective somatostatin peptidomimetics based on a constrained tryptophan scaffold. Journal of medicinal chemistry, 50(14), pp. 3397-401. Easton, Pa.: American Chemical Society 10.1021/jm070246f

Körner, Meike; Stöckli, Martin; Waser, Beatrice; Reubi, Jean Claude (2007). GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting. Journal of nuclear medicine, 48(5), pp. 736-43. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.106.038679

Zhang, Hanwen; Schuhmacher, Jochen; Waser, Beatrice; Wild, Damian; Eisenhut, Michael; Reubi, Jean Claude; Maecke, Helmut R (2007). DOTA-PESIN, a DOTA-conjugated bombesin derivative designed for the imaging and targeted radionuclide treatment of bombesin receptor-positive tumours. European journal of nuclear medicine and molecular imaging, 34(8), pp. 1198-208. Berlin: Springer 10.1007/s00259-006-0347-4

Körner, Meike; Reubi, Jean Claude (2007). NPY receptors in human cancer: a review of current knowledge. Peptides, 28(2), pp. 419-25. New York, N.Y.: Elsevier 10.1016/j.peptides.2006.08.037

Reubi, Jean Claude (2007). Targeting CCK receptors in human cancers. Current topics in medicinal chemistry, 7(12), pp. 1239-42. Hilversum: Bentham Science Publishers

Fainstein Day, Patricia; Frohman, Lawrence; Garcia Rivello, Hernan; Reubi, Jean Claude; Sevlever, Gustavo; Glerean, Mariela; Fernandez Gianotti, Tomas; Pietrani, Marcelo; Rabadan, Alejandra; Racioppi, Silvina; Bidlingmaier, Martin (2007). Ectopic growth hormone-releasing hormone secretion by a metastatic bronchial carcinoid tumor: a case with a non hypophysial intracranial tumor that shrank during long acting octreotide treatment. Pituitary, 10(3), pp. 311-9. Norwell, Mass.: Springer Science + Business Media 10.1007/s11102-007-0019-9

Körner, Meike; Hayes, Gregory M; Rehmann, Ruth; Zimmermann, Arthur; Scholz, Arne; Wiedenmann, Bertram; Miller, Laurence J; Reubi, Jean Claude (2006). Secretin receptors in the human liver: expression in biliary tract and cholangiocarcinoma, but not in hepatocytes or hepatocellular carcinoma. Journal of hepatology, 45(6), pp. 825-35. Amsterdam: Elsevier 10.1016/j.jhep.2006.06.016

Waser, Beatrice; Rehmann, Ruth; Rivier, Jean; Vale, Wylie; Reubi, Jean Claude (2006). CRF receptors in the rodent and human cardiovascular systems: Species differences. Peptides, 27(12), pp. 3029-38. New York, N.Y.: Elsevier 10.1016/j.peptides.2006.07.005

Cescato, Renzo; Schulz, Stefan; Waser, Beatrice; Eltschinger, Véronique; Rivier, Jean E; Wester, Hans-Jürgen; Culler, Michael; Ginj, Mihaela; Liu, Qisheng; Schonbrunn, Agnes; Reubi, Jean Claude (2006). Internalization of sst2, sst3, and sst5 receptors: effects of somatostatin agonists and antagonists. Journal of nuclear medicine, 47(3), pp. 502-11. New York, N.Y.: Society of Nuclear Medicine

Schmassmann, Adrian; Zoidl, Georg; Peskar, Brigitta M; Waser, Bea; Schmassmann-Suhijar, Diana; Gebbers, Jan-Olaf; Reubi, Jean Claude (2006). Role of the different isoforms of cyclooxygenase and nitric oxide synthase during gastric ulcer healing in cyclooxygenase-1 and -2 knockout mice. American journal of physiology - gastrointestinal and liver physiology, 290(4), G747-56. Bethesda, Md.: American Physiological Society 10.1152/ajpgi.00416.2005

Wild, Damian; Béhé, Martin; Wicki, Andreas; Storch, Daniel; Waser, Beatrice; Gotthardt, Martin; Keil, Boris; Christofori, Gerhard; Reubi, Jean Claude; Mäcke, Helmut R (2006). [Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting. Journal of nuclear medicine, 47(12), pp. 2025-33. New York, N.Y.: Society of Nuclear Medicine

Ginj, Mihaela; Zhang, Hanwen; Waser, Beatrice; Cescato, Renzo; Wild, Damian; Wang, Xuejuan; Erchegyi, Judit; Rivier, Jean; Mäcke, Helmut R; Reubi, Jean Claude (2006). Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 103(44), pp. 16436-41. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.0607761103

Grace, Christy Rani R; Erchegyi, Judit; Koerber, Steven C; Reubi, Jean Claude; Rivier, Jean; Riek, Roland (2006). Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR. Journal of medicinal chemistry, 49(15), pp. 4487-96. Easton, Pa.: American Chemical Society 10.1021/jm060363v

Lantry, Laura E; Cappelletti, Enrico; Maddalena, Mary Ellen; Fox, Jaclyn S; Feng, Weiwei; Chen, Jianqing; Thomas, Regi; Eaton, Stephen M; Bogdan, Nancy J; Arunachalam, Thangavel; Reubi, Jean Claude; Raju, Natarajan; Metcalfe, Edmund C; Lattuada, Luciano; Linder, Karen E; Swenson, Rolf E; Tweedle, Michael F; Nunn, Adrian D (2006). 177Lu-AMBA: Synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer. Journal of nuclear medicine, 47(7), pp. 1144-52. New York, N.Y.: Society of Nuclear Medicine

Kneifel, Stefan; Cordier, Dominik; Good, Stephan; Ionescu, Mihai C S; Ghaffari, Anthony; Hofer, Silvia; Kretzschmar, Martin; Tolnay, Markus; Apostolidis, Christos; Waser, Beatrice; Arnold, Marlene; Mueller-Brand, Jan; Maecke, Helmut R; Reubi, Jean Claude; Merlo, Adrian (2006). Local targeting of malignant gliomas by the diffusible peptidic vector 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-substance p. Clinical cancer research, 12(12), pp. 3843-50. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-05-2820

Gairí, Margarida; Saiz, Pilar; Madurga, Sergio; Roig, Xavier; Erchegyi, Judit; Koerber, Steven C; Reubi, Jean Claude; Rivier, Jean E; Giralt, Ernest (2006). Conformational analysis of a potent SSTR3-selective somatostatin analogue by NMR in water solution. Journal of Peptide Science, 12(2), pp. 82-91. Chichester: John Wiley & Sons 10.1002/psc.743

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