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Kivelä, Riikka; Bry, Maija; Robciuc, Marius R.; Räsänen, Markus; Taavitsainen, Miia; Silvola, Johanna M. U.; Saraste, Antti; Hulmi, Juha J.; Anisimov, Andrey; Mäyränpää, Mikko I.; Lindeman, Jan H.; Eklund, Lauri; Hellberg, Sanna; Hlushchuk, Ruslan; Zhuang, Zhen W.; Simons, Michael; Djonov, Valentin; Knuuti, Juhani; Mervaala, Eero and Alitalo, Kari (2014). VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO molecular medicine, 6(3), pp. 307-321. EMBO Press 10.1002/emmm.201303147
Bretscher, Peter; Egger, Julian; Shamshiev, Abdijapar; Trötzmüller, Martin; Köfeler, Harald; Carreira, Erick M; Kopf, Manfred; Freigang, Stefan Bernd (2015). Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2. EMBO molecular medicine, 7(5), pp. 593-607. EMBO Press 10.15252/emmm.201404702
Ghazal, Sanaz; Mc Kinnon, Brett; Zhou, Jichun; Müller, Martin; Men, Yi; Yang, Lihua; Mueller, Michael; Flannery, Clare; Huang, Yingqun; Taylor, Hugh S (2015). H19 lncRNA alters stromal cell growth via IGF signaling in the endometrium of women with endometriosis. EMBO molecular medicine, 7(8), pp. 996-1003. EMBO Press 10.15252/emmm.201505245
Loforese, Giulio; Malinka, Thomas; Keogh, Adrian; Baier, Felix; Simillion, Cedric André Marie; Montani, Matteo; Halazonetis, Thanos D; Candinas, Daniel; Keogh-Stroka, Deborah M. (2017). Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2. EMBO molecular medicine, 9(1), pp. 46-60. EMBO Press 10.15252/emmm.201506089
Scaglioni, Pier Paolo; Rabellino, Andrea; Yung, Thomas M.; Bernardi, Rosa; Choi, Sooyeon; Konstantinidou, Georgia; Nardella, Caterina; Cheng, Ke; Pandolfi, Pier Paolo (2012). Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence. EMBO molecular medicine, 4(7), pp. 594-602. EMBO Press 10.1002/emmm.201200233
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Mayr, Christoph H; Simon, Lukas M; Leuschner, Gabriela; Ansari, Meshal; Schniering, Janine; Geyer, Philipp E; Angelidis, Ilias; Strunz, Maximilian; Singh, Pawandeep; Kneidinger, Nikolaus; Reichenberger, Frank; Silbernagel, Edith; Böhm, Stephan; Adler, Heiko; Lindner, Michael; Maurer, Britta; Hilgendorff, Anne; Prasse, Antje; Behr, Jürgen; Mann, Matthias; ... (2021). Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers. EMBO molecular medicine, 13(4), e12871. EMBO Press 10.15252/emmm.202012871
Kappel, Sven; Peinelt, Christine (2022). Targeting CRAC channels in inflammatory bowel disease. EMBO molecular medicine, 14(9), e16489. EMBO Press 10.15252/emmm.202216489
Grant, Erica T; Boudaud, Marie; Muller, Arnaud; Macpherson, Andrew J; Desai, Mahesh S (2023). Maternal diet and gut microbiome composition modulate early-life immune development. EMBO molecular medicine, 15(8), e17241. EMBO Press 10.15252/emmm.202217241
Planas-Paz, Lara; Pliego-Mendieta, Alicia; Hagedorn, Catherine; Aguilera-Garcia, Domingo; Haberecker, Martina; Arnold, Fabian; Herzog, Marius; Bankel, Lorenz; Guggenberger, Roman; Steiner, Sabrina; Chen, Yanjiang; Kahraman, Abdullah; Zoche, Martin; Rubin, Mark A; Moch, Holger; Britschgi, Christian; Pauli, Chantal (2023). Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma. EMBO molecular medicine, 15(4), e16863. EMBO Press 10.15252/emmm.202216863
Sattler, Julia M; Keiber, Lukas; Abdelrahim, Aiman; Zheng, Xinyu; Jäcklin, Martin; Zechel, Luisa; Moreau, Catherine A; Steinbrück, Smilla; Fischer, Manuel; Janse, Chris J; Hoffmann, Angelika; Hentzschel, Franziska; Frischknecht, Friedrich (2024). Experimental vaccination by single dose sporozoite injection of blood-stage attenuated malaria parasites. EMBO molecular medicine, 16(9), pp. 2060-2079. EMBO Press 10.1038/s44321-024-00101-6
Chen, Hung-Chang; Mueller, Nico; Stott, Katherine; Kapeni, Chrysa; Rivers, Eilidh; Sauer, Carolin M; Beke, Flavio; Walsh, Stephen J; Ashman, Nicola; O'Brien, Louise; Rafati Fard, Amir; Godsinia, Arman; Li, Changtai; Joud, Fadwa; Giger, Olivier; Zlobec, Inti; Olan, Ioana; Aitken, Sarah J; Hoare, Matthew; Mair, Richard; ... (2024). Novel immunotherapeutics against LGR5 to target multiple cancer types. EMBO molecular medicine, 16(9), pp. 2233-2261. EMBO Press 10.1038/s44321-024-00121-2
Cardoso Alves, Ludmila; Berger, Michael; Koutsandreas, Thodoris; Kirschke, Nick; Lauer, Christoph; Spörri, Roman; Chatziioannou, Aristotelis; Corazza, Nadia; Krebs, Philippe (2020). Non-apoptotic TRAIL function modulates NK cell activity during viral infection. EMBO reports, 21(1), e48789. EMBO Press 10.15252/embr.201948789
Coraggio, Francesca; Püschel, Ringo; Marti, Alisha; Meister, Pierre (2018). Polycomb and Notch signaling regulate cell proliferation potential during Caenorhabditis elegans life cycle. Life science alliance, 2(1), e201800170. EMBO Press 10.26508/lsa.201800170
Dubrot, Juan; Duraes, Fernanda V; Harlé, Guillaume; Schlaeppi, Anjalie; Brighouse, Dale; Madelon, Natacha; Göpfert, Christine; Stokar von Neuforn, Nadine; Acha-Orbea, Hans; Reith, Walter; Gannagé, Monique; Hugues, Stephanie (2018). Absence of MHC-II expression by lymph node stromal cells results in autoimmunity. Life science alliance, 1(6), e201800164. EMBO Press 10.26508/lsa.201800164
Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry; Yu, Eric Chi-Wang; Mackie, Gillian M; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M and Allam, Ramanjaneyulu (2022). LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202101226
Jin, Jessica; Ba, Mame Aida; Wai, Chi Ho; Mohanty, Sanjib; Sahu, Praveen K; Pattnaik, Rajyabardhan; Pirpamer, Lukas; Fischer, Manuel; Heiland, Sabine; Lanzer, Michael; Frischknecht, Friedrich; Mueller, Ann-Kristin; Pfeil, Johannes; Majhi, Megharay; Cyrklaff, Marek; Wassmer, Samuel C; Bendszus, Martin; Hoffmann, Angelika (2022). Transcellular blood-brain barrier disruption in malaria-induced reversible brain edema. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202201402
Gerber, Markus; Suppanz, Ida; Oeljeklaus, Silke; Niemann, Moritz; Käser, Sandro; Warscheid, Bettina; Schneider, André; Dewar, Caroline E (2023). A Msp1-containing complex removes orphaned proteins in the mitochondrial outer membrane of T. brucei. Life science alliance, 6(11) EMBO Press 10.26508/lsa.202302004
Zhang, Fukai; Bechara, Sebastian; Nowacki, Mariusz (2024). Structural maintenance of chromosomes (SMC) proteins are required for DNA elimination in Paramecium. Life science alliance, 7(2) EMBO Press 10.26508/lsa.202302281
Sáinz-Jaspeado, Miguel; Proulx, Steven T; Ring, Sarah; Richards, Mark; Martinsson, Pernilla; Li, Xiujuan; Claesson-Welsh, Lena; Ulvmar, Maria H; Jin, Yi (2024). VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis. Life science alliance, 7(3) EMBO Press 10.26508/lsa.202302168
Safari, Fatemeh; Yeoh, Wen Jie; Perret-Gentil, Saskia; Klenke, Frank; Dolder, Silvia; Hofstetter, Wilhelm; Krebs, Philippe (2024). SHIP1 deficiency causes inflammation-dependent retardation in skeletal growth. Life science alliance, 7(5) EMBO Press 10.26508/lsa.202302297
Ryu, Hyunryul; Chung, Minhwan; Dobrzyński, Maciej; Fey, Dirk; Blum, Yannick; Lee, Sung Sik; Peter, Matthias; Kholodenko, Boris N; Jeon, Noo Li; Pertz, Olivier (2015). Frequency modulation of ERK activation dynamics rewires cell fate. Molecular systems biology, 11(11), p. 838. EMBO Press 10.15252/msb.20156458
Blum, Yannick; Mikelson, Jan; Dobrzynski, Maciej; Ryu, Hyunryul; Jacques, Marc-Antoine; Jeon, Noo Li; Khammash, Mustafa; Pertz, Olivier (2019). Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling. Molecular systems biology, 15(11), e8947. EMBO Press 10.15252/msb.20198947
Jacques, Marc-Antoine; Dobrzyński, Maciej; Gagliardi, Paolo Armando; Sznitman, Raphael; Pertz, Olivier (2021). CODEX, a neural network approach to explore signaling dynamics landscapes. Molecular systems biology, 17(4), e10026. EMBO Press 10.15252/msb.202010026
Dessauges, Coralie; Mikelson, Jan; Dobrzyński, Maciej; Jacques, Marc-Antoine; Frismantiene, Agne; Gagliardi, Paolo Armando; Khammash, Mustafa; Pertz, Olivier (2022). Optogenetic actuator - ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics. Molecular systems biology, 18(6), e10670. EMBO Press 10.15252/msb.202110670
Hellmann, H.; Hobbie, Lawrence; Chapman, Anngela; Dharmasiri, Sunethra; Dharmasiri, Nihal; del Pozo, Carlos; Reinhardt, Didier; Estelle, Mark (2003). Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis. The EMBO Journal, 22(13), pp. 3314-3325. EMBO Press 10.1093/emboj/cdg335
Planells-Cases, Rosa; Lutter, Darius; Guyader, Charlotte; Gerhards, Nora Merete; Ullrich, Florian; Elger, Deborah A; Kucukosmanoglu, Asli; Xu, Guotai; Voss, Felizia K; Reincke, S Momsen; Stauber, Tobias; Blomen, Vincent A; Vis, Daniel J; Wessels, Lodewyk F; Brummelkamp, Thijn R; Borst, Piet; Rottenberg, Sven; Jentsch, Thomas J (2015). Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs. The EMBO Journal, 34(24), pp. 2993-3008. EMBO Press 10.15252/embj.201592409
Grimm, C; Stefanovic, B; Schümperli, Daniel (1993). The low abundance of U7 snRNA is partly determined by its Sm binding site. The EMBO Journal, 12(3), pp. 1229-1238. EMBO Press
Melin, L; Soldati, D; Mital, R; Streit, A; Schümperli, Daniel (1992). Biochemical demonstration of complex formation of histone pre-mRNA with U7 small nuclear ribonucleoprotein and hairpin binding factors. The EMBO Journal, 11(2), pp. 691-697. EMBO Press
Galluzzi, Lorenzo; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cecconi, Francesco; Choi, Augustine M; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Debnath, Jayanta; Deretic, Vojo; Dikic, Ivan; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Fulda, Simone; Gewirtz, David A; Green, Douglas R; Hansen, Malene; ... (2017). Molecular definitions of autophagy and related processes. The EMBO Journal, 36(13), pp. 1811-1836. EMBO Press 10.15252/embj.201796697
Drobek, Ales; Moudra, Alena; Mueller, Daniel; Huranova, Martina; Horkova, Veronika; Pribikova, Michaela; Ivanek, Robert; Oberle, Susanne; Zehn, Dietmar; McCoy, Kathleen; Draber, Peter; Stepanek, Ondrej (2018). Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells. The EMBO Journal, 37(14) EMBO Press 10.15252/embj.201798518
Shashi, Vandana; Magiera, Maria M; Klein, Dennis; Zaki, Maha; Schoch, Kelly; Rudnik-Schöneborn, Sabine; Norman, Andrew; Lopes Abath Neto, Osorio; Dusl, Marina; Yuan, Xidi; Bartesaghi, Luca; De Marco, Patrizia; Alfares, Ahmed A; Marom, Ronit; Arold, Stefan T; Guzmán-Vega, Francisco J; Pena, Loren Dm; Smith, Edward C; Steinlin, Maja; Babiker, Mohamed Oe; ... (2018). Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration. The EMBO Journal, 37(23) EMBO Press 10.15252/embj.2018100540
Forrester, Alison; De Leonibus, Chiara; Grumati, Paolo; Fasana, Elisa; Piemontese, Marilina; Staiano, Leopoldo; Fregno, Ilaria; Raimondi, Andrea; Marazza, Alessandro; Bruno, Gemma; Iavazzo, Maria; Intartaglia, Daniela; Seczynska, Marta; van Anken, Eelco; Conte, Ivan; De Matteis, Maria Antonietta; Dikic, Ivan; Molinari, Maurizio; Settembre, Carmine (2019). A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex. The EMBO journal, 38(2) EMBO Press 10.15252/embj.201899847
Lee, Myoung‐Hoon; Jeon, Hwi Seong; Kim, Seu Ha; Chung, Joo Hee; Roppolo, Daniele; Lee, Hye‐Jung; Cho, Hong Joo; Tobimatsu, Yuki; Ralph, John; Park, Ohkmae K (2019). Lignin‐based barrier restricts pathogens to the infection site and confers resistance in plants (In Press). The EMBO journal EMBO Press 10.15252/embj.2019101948
Lorent, Julie; Kusnadi, Eric P; Hoef, Vincent; Rebello, Richard J; Leibovitch, Matthew; Ristau, Johannes; Chen, Shan; Lawrence, Mitchell G; Szkop, Krzysztof J; Samreen, Baila; Balanathan, Preetika; Rapino, Francesca; Close, Pierre; Bukczynska, Patricia; Scharmann, Karin; Takizawa, Itsuhiro; Risbridger, Gail P; Selth, Luke A; Leidel, Sebastian A; Lin, Qishan; ... (2019). Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression. The EMBO journal, 38(23), e101323. EMBO Press 10.15252/embj.2018101323
Dor, Yuval; Djonov, Valentin; Abramovitch, Rinat; Itin, Ahuva; Fishman, Glenn I; Carmeliet, Peter; Goelman, Gadi; Keshet, Eli (2002). Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. The EMBO journal, 21(8), pp. 1939-1947. EMBO Press 10.1093/emboj/21.8.1939
Pabis, Marta; Termathe, Martin; Ravichandran, Keerthiraju E; Kienast, Sandra D.; Krutyhołowa, Rościsław; Sokołowski, Mikołaj; Jankowska, Urszula; Grudnik, Przemysław; Leidel, Sebastian A.; Glatt, Sebastian (2020). Molecular basis for the bifunctional Uba4–Urm1 sulfur‐relay system in tRNA thiolation and ubiquitin‐like conjugation. The EMBO journal, 39(19) EMBO Press 10.15252/embj.2020105087
Lei, Jian; Ma-Lauer, Yue; Han, Yinze; Thoms, Matthias; Buschauer, Robert; Jores, Joerg; Thiel, Volker; Beckmann, Roland; Deng, Wen; Leonhardt, Heinrich; Hilgenfeld, Rolf; von Brunn, Albrecht (2021). The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation. The EMBO journal, 40(11), e102277. EMBO Press 10.15252/embj.2019102277
Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine M K; Choi, Mary E; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; ... (2021). Autophagy in major human diseases. The EMBO journal, 40(19), e108863. EMBO Press 10.15252/embj.2021108863
Sankowski, Roman; Ahmari, Jasmin; Mezö, Charlotte; Hrabě de Angelis, Anna Lena; Fuchs, Vidmante; Utermöhlen, Olaf; Buch, Thorsten; Blank, Thomas; Gomez de Agüero, Mercedes; Macpherson, Andrew J; Erny, Daniel (2021). Commensal microbiota divergently affect myeloid subsets in the mammalian central nervous system during homeostasis and disease. The EMBO journal, 40(23), e108605. EMBO Press 10.15252/embj.2021108605
Ravichandran, Keerthiraju E; Kaduhr, Lars; Skupien-Rabian, Bozena; Shvetsova, Ekaterina; Sokołowski, Mikołaj; Krutyhołowa, Ros Cisław; Kwasna, Dominika; Brachmann, Cindy; Lin, Sean; Guzman Perez, Sebastian; Wilk, Piotr; Kösters, Manuel; Grudnik, Przemysław; Jankowska, Urszula; Leidel, Sebastian A; Schaffrath, Raffael; Glatt, Sebastian (2022). E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation. The EMBO journal, 41(20), e111318. EMBO Press 10.15252/embj.2022111318
Singh, Aditi; Maurer-Alcalá, Xyrus X; Solberg, Therese; Haeussermann, Lilia; Gisler, Silvan; Ignarski, Michael; Swart, Estienne C; Nowacki, Mariusz (2022). Chromatin remodeling is required for sRNA-guided DNA elimination in Paramecium. The EMBO journal, 41(22), e111839. EMBO Press 10.15252/embj.2022111839
Couto, Joana Pinto; Vulin, Milica; Jehanno, Charly; Coissieux, Marie-May; Hamelin, Baptiste; Schmidt, Alexander; Ivanek, Robert; Sethi, Atul; Bräutigam, Konstantin; Frei, Anja L; Hager, Carolina; Manivannan, Madhuri; Gómez-Miragaya, Jorge; Obradović, Milan Ms; Varga, Zsuzsanna; Koelzer, Viktor H; Mertz, Kirsten D; Bentires-Alj, Mohamed (2023). Nicotinamide N-methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer. The EMBO journal, 42(13), e112559. EMBO Press 10.15252/embj.2022112559
Karousis, Evangelos D; Schubert, Katharina; Ban, Nenad (2024). Coronavirus takeover of host cell translation and intracellular antiviral response: a molecular perspective. The EMBO journal, 43(2), pp. 151-167. EMBO Press 10.1038/s44318-023-00019-8
Alaimo, Alessandro; Genovesi, Sacha; Annesi, Nicole; De Felice, Dario; Subedi, Saurav; Macchia, Alice; La Manna, Federico; Ciani, Yari; Vannuccini, Federico; Mugoni, Vera; Notarangelo, Michela; Libergoli, Michela; Broso, Francesca; Taulli, Riccardo; Ala, Ugo; Savino, Aurora; Cortese, Martina; Mirzaaghaei, Somayeh; Poli, Valeria; Bonapace, Ian Marc; ... (2024). Sterile inflammation via TRPM8 RNA-dependent TLR3-NF-kB/IRF3 activation promotes antitumor immunity in prostate cancer. The EMBO journal, 43(5), pp. 780-805. EMBO Press 10.1038/s44318-024-00040-5
Andronikou, Christina; Burdova, Kamila; Dibitetto, Diego; Lieftink, Cor; Malzer, Elke; Kuiken, Hendrik J; Gogola, Ewa; Ray Chaudhuri, Arnab; Beijersbergen, Roderick L; Hanzlikova, Hana; Jonkers, Jos; Rottenberg, Sven (2024). PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair. The EMBO journal, 43(6), pp. 1015-1042. EMBO Press 10.1038/s44318-024-00043-2
Marq, Jean-Baptiste; Gosetto, Margaux; Altenried, Aline; Vadas, Oscar; Maco, Bohumil; Dos Santos Pacheco, Nicolas; Tosetti, Nicolò; Soldati-Favre, Dominique; Lentini, Gaëlle (2024). Cytokinetic abscission in Toxoplasma gondii is governed by protein phosphatase 2A and the daughter cell scaffold complex. The EMBO journal, 43(17), pp. 3752-3786. EMBO Press 10.1038/s44318-024-00171-9
Knosp, Samuel; Kriegshauser, Lucie; Tatsumi, Kanade; Malherbe, Ludivine; Erhardt, Mathieu; Wiedemann, Gertrud; Bakan, Bénédicte; Kohchi, Takayuki; Reski, Ralf; Renault, Hugues (2024). An ancient role for CYP73 monooxygenases in phenylpropanoid biosynthesis and embryophyte development. The EMBO journal, 43(18), pp. 4092-4109. EMBO Press 10.1038/s44318-024-00181-7
