Efthimiou, Orestis

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Levine, Stephen Z; Yoshida, Kazufumi; Goldberg, Yair; Samara, Myrto; Cipriani, Andrea; Efthimiou, Orestis; Iwatsubo, Takeshi; Leucht, Stefan; Furukawa, Toshi A (2021). Linking the Mini-Mental State Examination, the Alzheimer's Disease Assessment Scale-Cognitive Subscale and the Severe Impairment Battery: evidence from individual participant data from five randomised clinical trials of donepezil. Evidence-Based Mental Health, 24(2), pp. 56-61. BMJ Publishing Group 10.1136/ebmental-2020-300184

McCutcheon, Robert; Pillinger, Toby; Welby, George; Vano, Luke; Cummings, Connor; Guo, Xin; Heron, Toni Ann; Efthimiou, Orestis; Cipriani, Andrea; Howes, Oliver (2021). Magnitude and variability of structural brain abnormalities in neuropsychiatric disease: protocol for a network meta-analysis of MRI studies. (In Press). Evidence-Based Mental Health BMJ Publishing Group 10.1136/ebmental-2020-300229

Karyotaki, Eirini; Efthimiou, Orestis; Miguel, Clara; Bermpohl, Frederic Maas Genannt; Furukawa, Toshi A; Cuijpers, Pim (2021). Internet-Based Cognitive Behavioral Therapy for Depression: A Systematic Review and Individual Patient Data Network Meta-analysis. JAMA psychiatry, 78(4), pp. 361-371. American Medical Association 10.1001/jamapsychiatry.2020.4364

Seo, Michael; White, Ian R; Furukawa, Toshi A; Imai, Hissei; Valgimigli, Marco; Egger, Matthias; Zwahlen, Marcel; Efthimiou, Orestis (2021). Comparing methods for estimating patient-specific treatment effects in individual patient data meta-analysis. Statistics in medicine, 40(6), pp. 1553-1573. Wiley-Blackwell 10.1002/sim.8859

Petropoulou, Maria; Efthimiou, Orestis; Rücker, Gerta; Schwarzer, Guido; Furukawa, Toshi A; Pompoli, Alessandro; Koek, Huiberdina L; Del Giovane, Cinzia; Rodondi, Nicolas; Mavridis, Dimitris (2021). A review of methods for addressing components of interventions in meta-analysis. PLoS ONE, 16(2), e0246631. Public Library of Science 10.1371/journal.pone.0246631

Ruffieux, Yann; Muchengeti, Mazvita; Egger, Matthias; Efthimiou, Orestis; Bartels, Lina; Olago, Victor; Davidović, Maša; Dhokotera, Tafadzwa; Bohlius, Julia; Singh, Elvira; Rohner, Eliane (2021). Immunodeficiency and Cancer in 3.5 Million People Living with Human Immunodeficiency Virus: the South African HIV Cancer Match Study. (In Press). Clinical infectious diseases Oxford University Press 10.1093/cid/ciab087

Miklowitz, David J; Efthimiou, Orestis; Furukawa, Toshi A; Scott, Jan; McLaren, Ross; Geddes, John R; Cipriani, Andrea (2021). Adjunctive Psychotherapy for Bipolar Disorder: A Systematic Review and Component Network Meta-analysis. JAMA psychiatry, 78(2), pp. 141-150. American Medical Association 10.1001/jamapsychiatry.2020.2993

Seo, Michael; Furukawa, Toshi A; Veroniki, Areti Angeliki; Pillinger, Toby; Tomlinson, Anneka; Salanti, Georgia; Cipriani, Andrea; Efthimiou, Orestis (2021). The Kilim plot: A tool for visualizing network meta-analysis results for multiple outcomes. Research Synthesis Methods, 12(1), pp. 86-95. Wiley 10.1002/jrsm.1428


Furukawa, Toshi A; Debray, Thomas P A; Akechi, Tatsuo; Yamada, Mitsuhiko; Kato, Tadashi; Seo, Michael; Efthimiou, Orestis (2020). Can personalized treatment prediction improve the outcomes, compared with the group average approach, in a randomized trial? Developing and validating a multivariable prediction model in a pragmatic megatrial of acute treatment for major depression. Journal of Affective Disorders, 274, pp. 690-697. Elsevier 10.1016/j.jad.2020.05.141

Wade, Ryckie G; Burr, Nicholas E; McCauley, Gordon; Bourke, Grainne; Efthimiou, Orestis (2020). The Comparative Efficacy of Chlorhexidine Gluconate and Povidone-iodine Antiseptics for the Prevention of Infection in Clean Surgery: A Systematic Review and Network Meta-analysis. (In Press). Annals of surgery Lippincott Williams & Wilkins 10.1097/SLA.0000000000004076

Siontis, George C.M.; Nikolakopoulou, Adriani; Efthimiou, Orestis; Räber, Lorenz; Windecker, Stephan; Jüni, Peter (2020). Evaluation of Cumulative Meta-analysis of Rare Events as a Tool for Clinical Trials Safety Monitoring. JAMA Network Open, 3(9), e2015031. American Medical Association 10.1001/jamanetworkopen.2020.15031

De Crescenzo, Franco; Garriga, Cesar; Tomlinson, Anneka; Coupland, Carol; Efthimiou, Orestis; Fazel, Seena; Hippisley-Cox, Julia; Cipriani, Andrea (2020). Real-world effect of antidepressants for depressive disorder in primary care: protocol of a population-based cohort study. Evidence-Based Mental Health, 23(3), pp. 122-126. BMJ Publishing Group 10.1136/ebmental-2020-300149

Pillinger, Toby; McCutcheon, Rob; Efthimiou, Orestis; Cipriani, Andrea; Howes, Oliver (18 May 2020). T79. Balancing effects with side-effects: examining comparative metabolic consequences of 18 antipsychotics in treatment of schizophrenia using network meta-analysis [abstract]. Schizophrenia Bulletin, 46(Supplement_1), S261-S262. 10.1093/schbul/sbaa029.639

Gillett, George; Tomlinson, Anneka; Efthimiou, Orestis; Cipriani, Andrea (2020). Predicting treatment effects in unipolar depression: A meta-review. Pharmacology & therapeutics, 212, p. 107557. Elsevier 10.1016/j.pharmthera.2020.107557

Tomlinson, Anneka; Furukawa, Toshi A; Efthimiou, Orestis; Salanti, Georgia; De Crescenzo, Franco; Singh, Ilina; Cipriani, Andrea (2020). Personalise antidepressant treatment for unipolar depression combining individual choices, risks and big data (PETRUSHKA): rationale and protocol. Evidence-Based Mental Health, 23(2), pp. 52-56. BMJ Publishing Group 10.1136/ebmental-2019-300118

Kalliala, I; Athanasiou, A; Veroniki, A A; Salanti, G.; Efthimiou, O.; Raftis, N; Bowden, S; Paraskevaidi, M; Aro, K; Arbyn, M; Bennett, P; Nieminen, P; Paraskevaidis, E; Kyrgiou, M (2020). Incidence and mortality from cervical cancer and other malignancies after treatment of cervical intraepithelial neoplasia: a systematic review and meta-analysis of the literature. Annals of oncology, 31(2), pp. 213-227. Oxford University Press 10.1016/j.annonc.2019.11.004

Efthimiou, Orestis; White, Ian R (2020). The dark side of the force: multiplicity issues in network meta-analysis and how to address them. Research Synthesis Methods, 11(1), pp. 105-122. Wiley 10.1002/jrsm.1377

Pillinger, Toby; McCutcheon, Robert A; Vano, Luke; Mizuno, Yuya; Arumuham, Atheeshaan; Hindley, Guy; Beck, Katherine; Natesan, Sridhar; Efthimiou, Orestis; Cipriani, Andrea; Howes, Oliver D (2020). Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis. The Lancet. Psychiatry, 7(1), pp. 64-77. Elsevier 10.1016/S2215-0366(19)30416-X


Athanasiou, Antonios; Veroniki, Areti Angeliki; Efthimiou, Orestis; Kalliala, Ilkka; Naci, Huseyin; Bowden, Sarah; Paraskevaidi, Maria; Martin-Hirsch, Pierre; Bennett, Philip; Paraskevaidis, Evangelos; Salanti, Georgia; Kyrgiou, Maria (2019). Comparative fertility and pregnancy outcomes after local treatment for cervical intraepithelial neoplasia and stage 1a1 cervical cancer: protocol for a systematic review and network meta-analysis from the CIRCLE group. BMJ open, 9(10), e028009. BMJ Publishing Group 10.1136/bmjopen-2018-028009

Schneider-Thoma, Johannes; Efthimiou, Orestis; Bighelli, Irene; Dörries, Carola; Huhn, Maximilian; Krause, Marc; Reichelt, Leonie; Röder, Hannah; Furukawa, Toshi A; Davis, John M; Leucht, Stefan (2019). Second-generation antipsychotic drugs and short-term somatic serious adverse events: a systematic review and meta-analysis. The Lancet. Psychiatry, 6(9), pp. 753-765. Elsevier 10.1016/S2215-0366(19)30223-8

Athanasiou, Antonios; Veroniki, Areti Angeliki; Efthimiou, Orestis; Kalliala, Ilkka; Naci, Huseyin; Bowden, Sarah; Paraskevaidi, Maria; Martin-Hirsch, Pierre; Bennett, Philip; Paraskevaidis, Evangelos; Salanti, Georgia; Kyrgiou, Maria (2019). Comparative efficacy and complication rates after local treatment for cervical intraepithelial neoplasia and stage 1a1 cervical cancer: protocol for a systematic review and network meta-analysis from the CIRCLE Group. BMJ open, 9(8), e028008. BMJ Publishing Group 10.1136/bmjopen-2018-028008

Efthimiou, Orestis (2019). Statistics in pills: meta-analysis of rare events. Evidence-Based Mental Health, 22(3), p. 102. BMJ Publishing Group 10.1136/ebmental-2019-300103

Efthimiou, Orestis; Rücker, Gerta; Schwarzer, Guido; Higgins, Julian P T; Egger, Matthias; Salanti, Georgia (2019). Network meta-analysis of rare events using the Mantel-Haenszel method. Statistics in medicine, 38(16), pp. 2992-3012. Wiley-Blackwell 10.1002/sim.8158

Efthimiou, Orestis; Mavridis, Dimitris; Nikolakopoulou, Adriani; Rücker, Gerta; Trelle, Sven; Egger, Matthias; Salanti, Georgia (2019). A model for meta-analysis of correlated binary outcomes: The case of split-body interventions. Statistical Methods in Medical Research, 28(7), pp. 1998-2014. SAGE Publications (UK and US) 10.1177/0962280217746436

Piccolo, Raffaele; Bonaa, Kaare H; Efthimiou, Orestis; Varenne, Olivier; Baldo, Andrea; Urban, Philip; Kaiser, Christoph; Remkes, Wouter; Räber, Lorenz; de Belder, Adam; van 't Hof, Arnoud W J; Stankovic, Goran; Lemos, Pedro A; Wilsgaard, Tom; Reifart, Jörg; Rodriguez, Alfredo E; Ribeiro, Expedito E; Serruys, Patrick W J C; Abizaid, Alex; Sabaté, Manel; ... (2019). Drug-eluting or bare-metal stents for percutaneous coronary intervention: a systematic review and individual patient data meta-analysis of randomised clinical trials. Lancet, 393(10190), pp. 2503-2510. Elsevier 10.1016/S0140-6736(19)30474-X

Shinohara, Kiyomi; Efthimiou, Orestis; Ostinelli, Edoardo G; Tomlinson, Anneka; Geddes, John R; Nierenberg, Andrew A; Ruhe, Henricus G; Furukawa, Toshi A; Cipriani, Andrea (2019). Comparative efficacy and acceptability of antidepressants in the long-term treatment of major depression: protocol for a systematic review and networkmeta-analysis. BMJ open, 9(5), e027574. BMJ Publishing Group 10.1136/bmjopen-2018-027574

Tomlinson, Anneka; Efthimiou, Orestis; Boaden, Katharine; New, Emma; Mather, Sarah; Salanti, Georgia; Imai, Hissei; Ogawa, Yusuke; Tajika, Aran; Kishimoto, Sanae; Kikuchi, Sino; Chevance, Astrid; Furukawa, Toshi A; Cipriani, Andrea (2019). Side effect profile and comparative tolerability of 21 antidepressants in the acute treatment of major depression in adults: protocol for a network meta-analysis. Evidence-Based Mental Health, 22(2), pp. 61-66. BMJ Publishing Group 10.1136/ebmental-2019-300087

Furukawa, Toshi A; Karyotaki, Eirini; Suganuma, Aya; Pompoli, Alessandro; Ostinelli, Edoardo G; Cipriani, Andrea; Cuijpers, Pim; Efthimiou, Orestis (2019). Dismantling, personalising and optimising internet cognitive-behavioural therapy for depression: a study protocol for individual participant data component network meta-analysis. BMJ open, 8(11), e026137. BMJ Publishing Group 10.1136/bmjopen-2018-026137


Pompoli, Alessandro; Furukawa, Toshi A; Efthimiou, Orestis; Imai, Hissei; Tajika, Aran; Salanti, Georgia (2018). Dismantling cognitive-behaviour therapy for panic disorder: a systematic review and component network meta-analysis. Psychological medicine, 48(12), pp. 1945-1953. Cambridge University Press 10.1017/S0033291717003919

Schneider-Thoma, Johannes; Efthimiou, Orestis; Huhn, Maximilian; Krause, Marc; Reichelt, Leonie; Röder, Hannah; Davis, John M; Salanti, Georgia; Leucht, Stefan (2018). Second-generation antipsychotic drugs and short-term mortality: a systematic review and meta-analysis of placebo-controlled randomised controlled trials. The Lancet. Psychiatry, 5(8), pp. 653-663. Elsevier 10.1016/S2215-0366(18)30177-9

Didden, EM; Ruffieux, Y; Hummel, N; Efthimiou, O; Reichenbach, S; Gsteiger, Sandro; Finckh, Axel; Fletcher, Christine; Salanti, G; Egger, Matthias; Work Package, IMI GetReal (2018). Prediction of Real-World Drug Effectiveness Prelaunch: Case Study in Rheumatoid Arthritis. Medical decision making, 38(6), pp. 719-729. Sage Publications 10.1177/0272989X18775975

Karcher, Helene; Fu, Shuai; Meng, Jie; Ankarfeldt, Mikkel Zöllner; Efthimiou, Orestis; Belger, Mark; Haro, Josep Maria; Abenhaim, Lucien; Nordon, Clementine (2018). The "RCT augmentation": a novel simulation method to add patient heterogeneity into phase III trials. BMC Medical research methodology, 18(1), p. 75. BioMed Central 10.1186/s12874-018-0534-6

Furukawa, Toshi A; Efthimiou, Orestis; Weitz, Erica S; Cipriani, Andrea; Keller, Martin B; Kocsis, James H; Klein, Daniel N; Michalak, Johannes; Salanti, Georgia; Cuijpers, Pim; Schramm, Elisabeth (2018). Cognitive-Behavioral Analysis System of Psychotherapy, Drug, or Their Combination for Persistent Depressive Disorder: Personalizing the Treatment Choice Using Individual Participant Data Network Metaregression. Psychotherapy and psychosomatics, 87(3), pp. 140-153. Karger 10.1159/000489227

Efthimiou, Orestis (2018). Practical guide to the meta-analysis of rare events. Evidence-Based Mental Health, 21(2), pp. 72-76. BMJ Publishing Group 10.1136/eb-2018-102911

Efthimiou, Orestis; Chaimani, Anna; Mavridis, Dimitris; Salanti, Georgia (2018). Network Meta-Analysis. In: Gatsonis, Constantine; Morton, Sally C. (eds.) Methods in comparative effectiveness research (pp. 341-384). Boca Raton: Taylor & Francis


Efthimiou, Orestis; Mavridis, Dimitris; Debray, Thomas P A; Samara, Myrto; Belger, Mark; Siontis, George C M; Leucht, Stefan; Salanti, Georgia (2017). Combining randomized and non-randomized evidence in network meta-analysis. Statistics in medicine, 36(8), pp. 1210-1226. Wiley-Blackwell 10.1002/sim.7223

Efthimiou, Orestis; Welton, Nicky; Samara, Myrto; Leucht, Stefan; Salanti, Georgia (2017). Α Markov model for longitudinal studies with incomplete dichotomous outcomes. Pharmaceutical Statistics, 16(2), pp. 122-132. Wiley 10.1002/pst.1794


Furukawa, Toshi A; Schramm, Elisabeth; Weitz, Erica S; Salanti, Georgia; Efthimiou, Orestis; Michalak, Johannes; Watanabe, Norio; Cipriani, Andrea; Keller, Martin B; Kocsis, James H; Klein, Daniel N; Cuijpers, Pim (2016). Cognitive-Behavioural Analysis System of Psychotherapy (CBASP), a drug, or their combination: differential therapeutics for persistent depressive disorder: a study protocol of an individual participant data network meta-analysis. BMJ open, 6(5), e011769. BMJ Publishing Group 10.1136/bmjopen-2016-011769

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