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Bessell, Emily; Finlay, Rachel E; James, Louisa K; Ludewig, Burkhard; Harris, Nicola L; Krebs, Philippe; Hepworth, Matthew R; Dubey, Lalit Kumar (2024). Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity. Cell reports, 43(8), p. 114620. Cell Press 10.1016/j.celrep.2024.114620
Safari, Fatemeh; Yeoh, Wen Jie; Perret-Gentil, Saskia; Klenke, Frank; Dolder, Silvia; Hofstetter, Wilhelm; Krebs, Philippe (2024). SHIP1 deficiency causes inflammation-dependent retardation in skeletal growth. Life science alliance, 7(5) EMBO Press 10.26508/lsa.202302297
Perez-Shibayama, Christian; Gil-Cruz, Cristina; Cadosch, Nadine; Lütge, Mechthild; Cheng, Hung-Wei; De Martin, Angelina; Frischmann, Kira; Joachimbauer, Anna; Onder, Lucas; Papadopoulou, Iliana; Papadopoulou, Chrysa; Ring, Sandra; Krebs, Philippe; Vu, Vivian P.; Nägele, Matthias P.; Rossi, Valentina A.; Parianos, Danaë; Zsilavecz, Valentin W.; Cooper, Leslie T.; Flammer, Andreas; ... (2024). Bone morphogenic protein-4 availability in the cardiac microenvironment controls inflammation and fibrosis in autoimmune myocarditis. Nature cardiovascular research Springer Nature 10.1038/s44161-024-00432-0
Yeoh, Wen Jie; Krebs, Philippe (2023). SHIP1 and its role for innate immune regulation - novel targets for immunotherapy. European journal of immunology, 53(12), e2350446. Wiley-VCH 10.1002/eji.202350446
van Os, Lisette; Yeoh, Wen Jie; Witz, Guillaume; Ferrari, Dario; Krebs, Philippe; Chandorkar, Yashoda; Zeinali, Soheila; Sengupta, Arunima; Guenat, Olivier (2023). Immune cell extravasation in an organ-on-chip to model lung inflammation. European journal of pharmaceutical sciences, 187, p. 106485. Elsevier 10.1016/j.ejps.2023.106485
Alizadeh Zeinabad, Hojjat; Yeoh, Wen Jie; Arif, Maryam; Lomora, Mihai; Banz, Yara; Riether, Carsten; Krebs, Philippe; Szegezdi, Eva (2023). Natural killer cell-mimic nanoparticles can actively target and kill acute myeloid leukemia cells. Biomaterials, 298(122126), p. 122126. Elsevier 10.1016/j.biomaterials.2023.122126
Ennis, Sarah; Conforte, Alessandra; O'Reilly, Eimear; Takanlu, Javid Sabour; Cichocka, Tatiana; Dhami, Sukhraj Pal; Nicholson, Pamela; Krebs, Philippe; Ó Broin, Pilib; Szegezdi, Eva (2023). Cell-cell interactome of the hematopoietic niche and its changes in acute myeloid leukemia. iScience, 26(6), p. 106943. Elsevier 10.1016/j.isci.2023.106943
Carone, Marianna; Spalinger, Marianne R; Gaultney, Robert A; Mezzenga, Raffaele; Hlavacková, Kristyna; Mookhoek, Aart; Krebs, Philippe; Rogler, Gerhard; Luciani, Paola; Aleandri, Simone (2023). Temperature-triggered in situ forming lipid mesophase gel for local treatment of ulcerative colitis. Nature Communications, 14(1), p. 3489. Springer Nature 10.1038/s41467-023-39013-3
Grabherr, Sarah; Waltenspühl, Alexandra; Büchler, Lorina; Lütge, Mechthild; Cheng, Hung-Wei; Caviezel-Firner, Sonja; Ludewig, Burkhard; Krebs, Philippe; Pikor, Natalia B (2023). An Innate Checkpoint Determines Immune Dysregulation and Immunopathology during Pulmonary Murine Coronavirus Infection. Journal of immunology, 210(6), pp. 774-785. American Association of Immunologists 10.4049/jimmunol.2200533
Gurtner, Alessandra; Borrelli, Costanza; Gonzalez-Perez, Ignacio; Bach, Karsten; Acar, Ilhan E; Núñez, Nicolás G; Crepaz, Daniel; Handler, Kristina; Vu, Vivian P; Lafzi, Atefeh; Stirm, Kristin; Raju, Deeksha; Gschwend, Julia; Basler, Konrad; Schneider, Christoph; Slack, Emma; Valenta, Tomas; Becher, Burkhard; Krebs, Philippe; Moor, Andreas E; ... (2023). Active eosinophils regulate host defense and immune responses in colitis. Nature, 615(7950), pp. 151-157. Macmillan Journals Ltd. 10.1038/s41586-022-05628-7
Le‐Trilling, Vu Thuy Khanh; Ebel, Jana‐Fabienne; Baier, Franziska; Wohlgemuth, Kerstin; Pfeifer, Kai Robin; Mookhoek, Aart; Krebs, Philippe; Determann, Madita; Katschinski, Benjamin; Adamczyk, Alexandra; Lange, Erik; Klopfleisch, Robert; Lange, Christian M.; Sokolova, Viktoriya; Trilling, Mirko; Westendorf, Astrid M. (2023). Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cells. European journal of immunology, 53(2), e2249940. Wiley 10.1002/eji.202249940
Krebs, Philippe; Peng, Hui; Duhan, Vikas (2023). Editorial: Natural killer cell plasticity and diversity in antiviral immunity. Frontiers in immunology, 14(1175111), p. 1175111. Frontiers Research Foundation 10.3389/fimmu.2023.1175111
Noti, Luca; Galván, José; Dawson, Heather; Lugli, Alessandro; Kirsch, Richard; Assarzadegan, Naziheh; Messenger, David; Krebs, Philippe; Berger, Martin D; Zlobec, Inti (2022). A combined spatial score of granzyme B and CD68 surpasses CD8 as an independent prognostic factor in TNM stage II colorectal cancer. BMC cancer, 22(1), p. 987. BioMed Central 10.1186/s12885-022-10048-x
Yeoh, Wen Jie; Vu, Vivian P; Krebs, Philippe (2022). IL-33 biology in cancer: An update and future perspectives. Cytokine, 157, p. 155961. Elsevier 10.1016/j.cyto.2022.155961
Safari, Fatemeh; Yeoh, Jeremy; Siegrist, Mark; Dolder, Silvia; Strunz, Franziska; Hofstetter, Willy; Krebs, Philippe (May 2022). Inositol Phosphatase SHIP1 – a Regulator of Osteoclast Lineage Cell Development and Activity. Bone reports, 16, p. 101404. Elsevier 10.1016/j.bonr.2022.101404
Cardoso Alves, Ludmila; Corazza, Nadia; Micheau, Olivier; Krebs, Philippe (2021). The multifaceted role of TRAIL signaling in cancer and immunity. The FEBS journal, 288(19), pp. 5530-5554. FEBS Press 10.1111/febs.15637
Ring, Sandra S; Cupovic, Jovana; Onder, Lucas; Lütge, Mechthild; Perez-Shibayama, Christian; Gil-Cruz, Cristina; Scandella, Elke; De Martin, Angelina; Mörbe, Urs; Hartmann, Fabienne; Wenger, Robert; Spiegl, Matthias; Besse, Andrej; Bonilla, Weldy V; Stemeseder, Felix; Schmidt, Sarah; Orlinger, Klaus K; Krebs, Philippe; Ludewig, Burkhard and Flatz, Lukas (2021). Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment. Nature communications, 12(1), p. 4734. Nature Publishing Group 10.1038/s41467-021-25057-w
Cupovic, Jovana; Ring, Sandra S; Onder, Lucas; Colston, Julia M; Lütge, Mechthild; Cheng, Hung-Wei; De Martin, Angelina; Provine, Nicholas M; Flatz, Lukas; Oxenius, Annette; Scandella, Elke; Krebs, Philippe; Engeler, Daniel; Klenerman, Paul; Ludewig, Burkhard (2021). Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8+ T cells. Nature immunology, 22(8), pp. 1042-1051. Nature Publishing Group 10.1038/s41590-021-00969-3
Palmieri, Vittoria; Ebel, Jana-Fabienne; Ngo Thi Phuong, Nhi; Klopfleisch, Robert; Vu, Vivian Pham; Adamczyk, Alexandra; Zöller, Julia; Riedel, Christian; Buer, Jan; Krebs, Philippe; Hansen, Wiebke; Pastille, Eva; Westendorf, Astrid M. (2021). Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunity. Mucosal immunology, 14(4), pp. 923-936. Springer Nature 10.1038/s41385-021-00386-7
Adamczyk, Alexandra; Pastille, Eva; Kehrmann, Jan; Vu, Vivian P.; Geffers, Robert; Wasmer, Marie-Hélène; Kasper, Stefan; Schuler, Martin; Lange, Christian M; Muggli, Beat; Rau, Tilman T.; Klein, Diana; Hansen, Wiebke; Krebs, Philippe; Buer, Jan; Westendorf, Astrid M (2021). GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer. Cancer research, 81(11), pp. 2970-2982. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2133
Ercolano, Giuseppe; Gomez-Cadena, Alejandra; Dumauthioz, Nina; Vanoni, Giulia; Kreutzfeldt, Mario; Wyss, Tania; Michalik, Liliane; Loyon, Romain; Ianaro, Angela; Ho, Ping-Chih; Borg, Christophe; Kopf, Manfred; Merkler, Doron; Krebs, Philippe; Romero, Pedro; Trabanelli, Sara; Jandus, Camilla (2021). PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions. Nature Communications, 12(1), p. 2538. Springer Nature 10.1038/s41467-021-22764-2
Leimkühler, Nils B.; Gleitz, Hélène F.E.; Ronghui, Li; Snoeren, Inge A.M.; Fuchs, Stijn N.R.; Nagai, James S.; Banjanin, Bella; Lam, King H.; Vogl, Thomas; Kuppe, Christoph; Stalmann, Ursula S.A.; Büsche, Guntram; Kreipe, Hans; Gütgemann, Ines; Krebs, Philippe; Banz, Yara; Boor, Peter; Tai, Evelyn Wing-Ying; Brümmendorf, Tim H.; Koschmieder, Steffen; ... (2021). Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. Cell stem cell, 28(4), 637-652.e8. Elsevier 10.1016/j.stem.2020.11.004
Safari, Fatemeh; Yeoh, Jeremy; Bringardner, Margaux; Siegrist, Mark; Dolder, Silvia; Strunz, Franziska; Hofstetter, Willy; Krebs, Philippe (April 2021). The inositol phosphatase SHIP1 regulates skeletal development. Bone reports, 14, p. 100795. Elsevier 10.1016/j.bonr.2021.100795
Duhan, Vikas; Khairnar, Vishal; Kitanovski, Simo; Hamdan, Thamer A; Klein, Andrés D; Lang, Judith; Ali, Murtaza; Adomati, Tom; Bhat, Hilal; Friedrich, Sarah-Kim; Li, Fanghui; Krebs, Philippe; Futerman, Anthony H; Addo, Marylyn M; Hardt, Cornelia; Hoffmann, Daniel; Lang, Philipp A; Lang, Karl S (2021). Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells. Frontiers in immunology, 11, p. 607889. Frontiers Research Foundation 10.3389/fimmu.2020.607889
Lee, SungKyoung; Sears, Matthew J.; Zhang, Zijun; Li, Hong; Salhab, Imad; Krebs, Philippe; Xing, Yi; Nah, Hyun-Duck; Williams, Trevor; Carstens, Russ P. (2020). Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development, 147(21), pp. 1-13. Company of Biologists Limited 10.1242/dev.187369
Cardoso Alves, Ludmila; Berger, Michael; Koutsandreas, Thodoris; Kirschke, Nick; Lauer, Christoph; Spörri, Roman; Chatziioannou, Aristotelis; Corazza, Nadia; Krebs, Philippe (2020). Non-apoptotic TRAIL function modulates NK cell activity during viral infection. EMBO reports, 21(1), e48789. EMBO Press 10.15252/embr.201948789
Thoo, Lester; Noti, Mario; Krebs, Philippe (2019). Keep calm: the intestinal barrier at the interface of peace and war. Cell death & disease, 10(849), pp. 1-13. Springer Nature 10.1038/s41419-019-2086-z
Pastille, Eva; Wasmer, Marie-Hélène Christin; Adamczyk, Alexandra; Vu, Vivian Pham; Mager, Lukas F; Phuong, Nhi Ngo Thi; Palmieri, Vittoria; Simillion, Cedric André Marie; Hansen, Wiebke; Kasper, Stefan; Schuler, Martin; Muggli, Beat; McCoy, Kathy D; Buer, Jan; Zlobec, Inti; Westendorf, Astrid M; Krebs, Philippe (2019). The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer. Mucosal immunology, 12(4), pp. 990-1003. Nature Publishing Group 10.1038/s41385-019-0176-y
Schürch, Christian M; Rölli, Matthias A.; Forster, Stefan; Wasmer, Marie-Hélène; Brühl, Frido; Maire, Renaud S.; Di Pancrazio, Sergio; Ruepp, Marc-David; Giger, Roland; Perren, Aurel; Schmitt, Anja M.; Krebs, Philippe; Charles, Roch-Philippe; Dettmer, Matthias S. (2019). Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy. Thyroid, 29(7), pp. 979-992. Mary Ann Liebert 10.1089/thy.2018.0555
Saurer, Leslie; Zysset, Daniel; Rihs, Silvia; Mager, Lukas; Gusberti, Matteo; Simillion, Cedric; Lugli, Alessandro; Zlobec, Inti; Krebs, Philippe; Müller, Christoph (2017). TREM-1 promotes intestinal tumorigenesis. Scientific Reports, 7(1), p. 14870. Nature Publishing Group 10.1038/s41598-017-14516-4
Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136
Mager, Lukas Franz; Kölzer, Viktor Hendrik; Stuber Roos, Regula; Thoo Sin Lang, Lester; Keller, Irene; Köck, Ivonne; Langenegger, Maya; Simillion, Cedric; Pfister, Simona P; Faderl, Martin Richard; Genitsch Gratwohl, Vera; Tcymbarevich, Irina; Juillerat, Pascal; Li, Xiaohong; Xia, Yu; Karamitopoulou, Evanthia; Lyck, Ruth; Zlobec, Inti; Hapfelmeier, Siegfried Hektor; Bruggmann, Rémy; ... (2017). The ESRP1-GPR137 axis contributes to intestinal pathogenesis. eLife, 6 eLife Sciences Publications 10.7554/eLife.28366
Wasmer, Marie-Hélène; Krebs, Philippe (2017). The Role of IL-33-Dependent Inflammation in the Tumor Microenvironment. Frontiers in immunology, 7(682), p. 682. Frontiers Research Foundation 10.3389/fimmu.2016.00682
Mertz, Kirsten D; Mager, Lukas F.; Wasmer, Marie-Hélène; Thiesler, Thore; Kölzer, Viktor H.; Ruzzante, Giulia; Joller, Stefanie; Murdoch, Jenna R; Brümmendorf, Thomas; Genitsch Gratwohl, Vera; Lugli, Alessandro; Cathomas, Gieri; Moch, Holger; Weber, Achim; Zlobec, Inti; Junt, Tobias; Krebs, Philippe (2016). The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice. Oncoimmunology, 5(1), e1062966. Landes Bioscience 10.1080/2162402X.2015.1062966
Mager, Lukas; Wasmer, Marie-Hélène; Rau, Tilman; Krebs, Philippe (2016). Cytokine-Induced Modulation of Colorectal Cancer. Frontiers in oncology, 6(96), p. 96. Frontiers Research Foundation 10.3389/fonc.2016.00096
Siggs, Owen M.; Popkin, Daniel L.; Krebs, Philippe; Li, Xiaohong; Tang, Miao; Zhan, Xiaoming; Zeng, Ming; Lin, Pei; Xia, Yu; Oldstone, Michael B. A.; Cornall, Richard J.; Beutler, Bruce (2015). Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 112(42), E5706-E5714. National Academy of Sciences NAS 10.1073/pnas.1515619112
Mager, Lukas; Riether, Carsten; Schürch, Christian; Banz Wälti, Yara; Wasmer, Marie-Hélène Christin; Stuber Roos, Regula; Theocharides, Alexandre; Li, Xiaohong; Xia, Yu; Saito, Hirohisa; Nakae, Susumu; Baerlocher, Gabriela M.; Manz, Markus G; McCoy, Kathleen; Macpherson, Andrew; Ochsenbein, Adrian; Beutler, Bruce; Krebs, Philippe (2015). IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms. Journal of clinical investigation, 125(7), pp. 2579-2591. American Society for Clinical Investigation 10.1172/JCI77347
Arnold, Carrie N; Barnes, Michael J; Berger, Michael; Blasius, Amanda L; Brandl, Katharina; Croker, Ben; Crozat, Karine; Du, Xin; Eidenschenk, Celine; Georgel, Philippe; Hoebe, Kasper; Huang, Hua; Jiang, Zhengfan; Krebs, Philippe; La Vine, Diantha; Li, Xiaohong; Lyon, Stephen; Moresco, Eva Marie Y; Murray, Anne R; Popkin, Daniel L; ... (2012). ENU-induced phenovariance in mice: inferences from 587 mutations. BMC research notes, 5, p. 577. London: Biomed Central 10.1186/1756-0500-5-577
Blasius, Amanda L.; Krebs, Philippe; Sullivan, Brian M.; Oldstone, Michael B.; Popkin, Daniel L. (2012). Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection. PLoS pathogens, 8(9), e1002915. San Francisco, Calif.: Public Library of Science 10.1371/journal.ppat.1002915
Wingender, Gerhard; Stepniak, Dariusz; Krebs, Philippe; Lin, Lin; McBride, Sara; Wei, Bo; Braun, Jonathan; Mazmanian, Sarkis K; Kronenberg, Mitchell (2012). Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. Gastroenterology, 143(2), pp. 418-28. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2012.04.017
Krebs, Philippe; Fan, Weiwei; Chen, Yen-Hui; Tobita, Kimimasa; Downes, Michael R; Wood, Malcolm R; Sun, Lei; Li, Xiaohong; Xia, Yu; Ding, Ning; Spaeth, Jason M; Moresco, Eva Marie Y; Boyer, Thomas G; Lo, Cecilia Wen Ya; Yen, Jeffrey; Evans, Ronald M; Beutler, Bruce (2011). Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 108(49), pp. 19678-82. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.1117835108
