Krebs, Philippe

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Cardoso Alves, Ludmila; Corazza, Nadia; Micheau, Olivier; Krebs, Philippe (2021). The multifaceted role of TRAIL signaling in cancer and immunity. The FEBS journal, 288(19), pp. 5530-5554. FEBS Press 10.1111/febs.15637

Ring, Sandra S; Cupovic, Jovana; Onder, Lucas; Lütge, Mechthild; Perez-Shibayama, Christian; Gil-Cruz, Cristina; Scandella, Elke; De Martin, Angelina; Mörbe, Urs; Hartmann, Fabienne; Wenger, Robert; Spiegl, Matthias; Besse, Andrej; Bonilla, Weldy V; Stemeseder, Felix; Schmidt, Sarah; Orlinger, Klaus K; Krebs, Philippe; Ludewig, Burkhard and Flatz, Lukas (2021). Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment. Nature communications, 12(1), p. 4734. Nature Publishing Group 10.1038/s41467-021-25057-w

Cupovic, Jovana; Ring, Sandra S; Onder, Lucas; Colston, Julia M; Lütge, Mechthild; Cheng, Hung-Wei; De Martin, Angelina; Provine, Nicholas M; Flatz, Lukas; Oxenius, Annette; Scandella, Elke; Krebs, Philippe; Engeler, Daniel; Klenerman, Paul; Ludewig, Burkhard (2021). Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8+ T cells. Nature immunology, 22(8), pp. 1042-1051. Nature Publishing Group 10.1038/s41590-021-00969-3

Palmieri, Vittoria; Ebel, Jana-Fabienne; Ngo Thi Phuong, Nhi; Klopfleisch, Robert; Vu, Vivian Pham; Adamczyk, Alexandra; Zöller, Julia; Riedel, Christian; Buer, Jan; Krebs, Philippe; Hansen, Wiebke; Pastille, Eva; Westendorf, Astrid M. (2021). Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunity. Mucosal immunology, 14(4), pp. 923-936. Springer Nature 10.1038/s41385-021-00386-7

Adamczyk, Alexandra; Pastille, Eva; Kehrmann, Jan; Vu, Vivian P.; Geffers, Robert; Wasmer, Marie-Hélène; Kasper, Stefan; Schuler, Martin; Lange, Christian M; Muggli, Beat; Rau, Tilman T.; Klein, Diana; Hansen, Wiebke; Krebs, Philippe; Buer, Jan; Westendorf, Astrid M (2021). GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer. Cancer research, 81(11), pp. 2970-2982. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2133

Ercolano, Giuseppe; Gomez-Cadena, Alejandra; Dumauthioz, Nina; Vanoni, Giulia; Kreutzfeldt, Mario; Wyss, Tania; Michalik, Liliane; Loyon, Romain; Ianaro, Angela; Ho, Ping-Chih; Borg, Christophe; Kopf, Manfred; Merkler, Doron; Krebs, Philippe; Romero, Pedro; Trabanelli, Sara; Jandus, Camilla (2021). PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions. Nature Communications, 12(1), p. 2538. Springer Nature 10.1038/s41467-021-22764-2

Leimkühler, Nils B.; Gleitz, Hélène F.E.; Ronghui, Li; Snoeren, Inge A.M.; Fuchs, Stijn N.R.; Nagai, James S.; Banjanin, Bella; Lam, King H.; Vogl, Thomas; Kuppe, Christoph; Stalmann, Ursula S.A.; Büsche, Guntram; Kreipe, Hans; Gütgemann, Ines; Krebs, Philippe; Banz, Yara; Boor, Peter; Tai, Evelyn Wing-Ying; Brümmendorf, Tim H.; Koschmieder, Steffen; ... (2021). Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. Cell stem cell, 28(4), 637-652.e8. Elsevier 10.1016/j.stem.2020.11.004

Duhan, Vikas; Khairnar, Vishal; Kitanovski, Simo; Hamdan, Thamer A; Klein, Andrés D; Lang, Judith; Ali, Murtaza; Adomati, Tom; Bhat, Hilal; Friedrich, Sarah-Kim; Li, Fanghui; Krebs, Philippe; Futerman, Anthony H; Addo, Marylyn M; Hardt, Cornelia; Hoffmann, Daniel; Lang, Philipp A; Lang, Karl S (2021). Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells. Frontiers in immunology, 11, p. 607889. Frontiers Research Foundation 10.3389/fimmu.2020.607889

Lee, SungKyoung; Sears, Matthew J.; Zhang, Zijun; Li, Hong; Salhab, Imad; Krebs, Philippe; Xing, Yi; Nah, Hyun-Duck; Williams, Trevor; Carstens, Russ P. (2020). Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development, 147(21), pp. 1-13. Company of Biologists Limited 10.1242/dev.187369

Cardoso Alves, Ludmila; Berger, Michael; Koutsandreas, Thodoris; Kirschke, Nick; Lauer, Christoph; Spörri, Roman; Chatziioannou, Aristotelis; Corazza, Nadia; Krebs, Philippe (2020). Non-apoptotic TRAIL function modulates NK cell activity during viral infection. EMBO reports, 21(1), e48789. EMBO Press 10.15252/embr.201948789

Thoo, Lester; Noti, Mario; Krebs, Philippe (2019). Keep calm: the intestinal barrier at the interface of peace and war. Cell death & disease, 10(849), pp. 1-13. Springer Nature 10.1038/s41419-019-2086-z

Pastille, Eva; Wasmer, Marie-Hélène Christin; Adamczyk, Alexandra; Vu, Vivian Pham; Mager, Lukas F; Phuong, Nhi Ngo Thi; Palmieri, Vittoria; Simillion, Cedric André Marie; Hansen, Wiebke; Kasper, Stefan; Schuler, Martin; Muggli, Beat; McCoy, Kathy D; Buer, Jan; Zlobec, Inti; Westendorf, Astrid M; Krebs, Philippe (2019). The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer. Mucosal immunology, 12(4), pp. 990-1003. Nature Publishing Group 10.1038/s41385-019-0176-y

Schürch, Christian M; Rölli, Matthias A.; Forster, Stefan; Wasmer, Marie-Hélène; Brühl, Frido; Maire, Renaud S.; Di Pancrazio, Sergio; Ruepp, Marc-David; Giger, Roland; Perren, Aurel; Schmitt, Anja M.; Krebs, Philippe; Charles, Roch-Philippe; Dettmer, Matthias S. (2019). Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy. Thyroid, 29(7), pp. 979-992. Mary Ann Liebert 10.1089/thy.2018.0555

Saurer, Leslie; Zysset, Daniel; Rihs, Silvia; Mager, Lukas; Gusberti, Matteo; Simillion, Cedric; Lugli, Alessandro; Zlobec, Inti; Krebs, Philippe; Müller, Christoph (2017). TREM-1 promotes intestinal tumorigenesis. Scientific Reports, 7(1), p. 14870. Nature Publishing Group 10.1038/s41598-017-14516-4

Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136

Mager, Lukas Franz; Kölzer, Viktor Hendrik; Stuber Roos, Regula; Thoo Sin Lang, Lester; Keller, Irene; Köck, Ivonne; Langenegger, Maya; Simillion, Cedric; Pfister, Simona P; Faderl, Martin Richard; Genitsch Gratwohl, Vera; Tcymbarevich, Irina; Juillerat, Pascal; Li, Xiaohong; Xia, Yu; Karamitopoulou, Evanthia; Lyck, Ruth; Zlobec, Inti; Hapfelmeier, Siegfried Hektor; Bruggmann, Rémy; ... (2017). The ESRP1-GPR137 axis contributes to intestinal pathogenesis. eLife, 6 eLife Sciences Publications 10.7554/eLife.28366

Wasmer, Marie-Hélène; Krebs, Philippe (2017). The Role of IL-33-Dependent Inflammation in the Tumor Microenvironment. Frontiers in immunology, 7(682), p. 682. Frontiers Research Foundation 10.3389/fimmu.2016.00682

Mertz, Kirsten D; Mager, Lukas F.; Wasmer, Marie-Hélène; Thiesler, Thore; Kölzer, Viktor H.; Ruzzante, Giulia; Joller, Stefanie; Murdoch, Jenna R; Brümmendorf, Thomas; Genitsch Gratwohl, Vera; Lugli, Alessandro; Cathomas, Gieri; Moch, Holger; Weber, Achim; Zlobec, Inti; Junt, Tobias; Krebs, Philippe (2016). The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice. Oncoimmunology, 5(1), e1062966. Landes Bioscience 10.1080/2162402X.2015.1062966

Mager, Lukas; Wasmer, Marie-Hélène; Rau, Tilman; Krebs, Philippe (2016). Cytokine-Induced Modulation of Colorectal Cancer. Frontiers in oncology, 6(96), p. 96. Frontiers Research Foundation 10.3389/fonc.2016.00096

Siggs, Owen M.; Popkin, Daniel L.; Krebs, Philippe; Li, Xiaohong; Tang, Miao; Zhan, Xiaoming; Zeng, Ming; Lin, Pei; Xia, Yu; Oldstone, Michael B. A.; Cornall, Richard J.; Beutler, Bruce (2015). Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 112(42), E5706-E5714. National Academy of Sciences NAS 10.1073/pnas.1515619112

Mager, Lukas; Riether, Carsten; Schürch, Christian; Banz Wälti, Yara; Wasmer, Marie-Hélène Christin; Stuber Roos, Regula; Theocharides, Alexandre; Li, Xiaohong; Xia, Yu; Saito, Hirohisa; Nakae, Susumu; Baerlocher, Gabriela M.; Manz, Markus G; McCoy, Kathleen; Macpherson, Andrew; Ochsenbein, Adrian; Beutler, Bruce; Krebs, Philippe (2015). IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms. Journal of clinical investigation, 125(7), pp. 2579-2591. American Society for Clinical Investigation 10.1172/JCI77347

Arnold, Carrie N; Barnes, Michael J; Berger, Michael; Blasius, Amanda L; Brandl, Katharina; Croker, Ben; Crozat, Karine; Du, Xin; Eidenschenk, Celine; Georgel, Philippe; Hoebe, Kasper; Huang, Hua; Jiang, Zhengfan; Krebs, Philippe; La Vine, Diantha; Li, Xiaohong; Lyon, Stephen; Moresco, Eva Marie Y; Murray, Anne R; Popkin, Daniel L; ... (2012). ENU-induced phenovariance in mice: inferences from 587 mutations. BMC research notes, 5, p. 577. London: Biomed Central 10.1186/1756-0500-5-577

Blasius, Amanda L.; Krebs, Philippe; Sullivan, Brian M.; Oldstone, Michael B.; Popkin, Daniel L. (2012). Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection. PLoS pathogens, 8(9), e1002915. San Francisco, Calif.: Public Library of Science 10.1371/journal.ppat.1002915

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