Largiadèr, Carlo Rodolfo

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Brigger, D.; Horn, M. P.; Pennington, L. F.; Powell, A. E.; Siegrist, D.; Weber, B.; Engler, O.; Piezzi, V.; Damonti, L.; Iseli, P.; Hauser, C.; Froehlich, T. K.; Villiger, P. M.; Bachmann, Martin F.; Leib, S. L.; Bittel, P.; Fiedler, M.; Largiadèr, C.; Marschall, J.; Stalder, H.; ... (2021). Accuracy of serological testing for SARS-CoV-2 antibodies: first results of a large mixed-method evaluation study. Allergy, 76(3), pp. 853-865. Wiley 10.1111/all.14608


Hamzic, Seid; Aebi, Stefan; Joerger, Markus; Montemurro, Michael; Ansari, Marc; Amstutz, Ursula; Largiadèr, Carlo (2020). Fluoropyrimidine chemotherapy: recommendations for DPYD genotyping and therapeutic drug monitoring of the Swiss Group of Pharmacogenomics and Personalised Therapy. Swiss medical weekly, 150, w20375. EMH Media 10.4414/smw.2020.20375

Kremer Hovinga, Johanna A.; Braschler, Thomas R; Buchkremer, Florian; Farese, Stefan; Hengartner, Heinz; Lovey, Pierre-Yves; Largiadèr, Carlo R.; Mansouri Taleghani, Behrouz; Tarasco, Erika (2020). Insights from the Hereditary Thrombotic Thrombocytopenic Purpura Registry: Discussion of Key Findings Based on Individual Cases from Switzerland. Hämostaseologie, 40(S 01), S5-S14. Thieme 10.1055/a-1282-2264

Cismaru, Anca Liliana; Rudin, Deborah; Ibañez, Luisa; Liakoni, Evangelia; Bonadies, Nicolas; Kreutz, Reinhold; Carvajal, Alfonso; Lucena, Maria Isabel; Martin, Javier; Sancho Ponce, Esther; Molokhia, Mariam; Eriksson, Niclas; EuDAC, Collaborators; Krähenbühl, Stephan; Largiadèr, Carlo R.; Haschke, Manuel Martin; Hallberg, Pär; Wadelius, Mia; Amstutz, Ursula (2020). Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations. Genes, 11(11) MDPI, Molecular Diversity Preservation International 10.3390/genes11111275

Schaerer, Dominic; Froehlich, Tanja K.; Hamzic, Seid; Offer, Steven M.; Diasio, Robert B.; Joerger, Markus; Amstutz, Ursula; Largiadèr, Carlo R. (2020). A Novel Nomenclature for Repeat Motifs in the Thymidylate Synthase Enhancer Region and Its Relevance for Pharmacogenetic Studies. Journal of personalized medicine, 10(4) MDPI 10.3390/jpm10040181

Freiburghaus, Katrin; Leichtle, Alexander Benedikt; Nakas, Christos T.; Fiedler, Georg M.; Largiadèr, Carlo R. (2020). Effects of Freezing and Thawing Procedures on Selected Clinical Chemistry Parameters in Plasma. Biopreservation and biobanking, 18(4), pp. 297-304. Liebert 10.1089/bio.2020.0005

Tippenhauer, Kevin; Philips, Marwin; Largiadèr, Carlo R.; Sariyar, Murat; Bürkle, Thomas (2020). Integrating Pharmacogenetic Decision Support into a Clinical Information System. Studies in health technology and informatics, 270, pp. 618-622. IOS Press 10.3233/SHTI200234

Rubin, Mark; Largiadèr, Carlo; Staub, Timo (2020). Das Bern Center for Precision Medicine (BCPM). Schweizer Krebsbulletin / Bulletin suisse du cancer(01/20), pp. 48-50. Bern: Istituto oncologico della Svizzera Italiana

Hamzic, Seid; Kummer, Dominic; Froehlich, Tanja K.; Joerger, Markus; Aebi, Stefan; Palles, Claire; Thomlinson, Ian; Meulendijks, Didier; Schellens, Jan H M; García-González, Xandra; López-Fernández, Luis A; Amstutz, Ursula; Largiadèr, Carlo R. (2020). Evaluating the role of ENOSF1 and TYMS variants as predictors in fluoropyrimidine-related toxicities: An IPD meta-analysis. Pharmacological research, 152, p. 104594. Elsevier 10.1016/j.phrs.2019.104594

Zysset-Burri, Denise C.; Keller, Irene; Berger, Lieselotte E.; Largiadèr, Carlo R.; Wittwer, Matthias; Wolf, Sebastian; Zinkernagel, Martin S. (2020). Associations of the intestinal microbiome with the complement system in neovascular age-related macular degeneration. NPJ genomic medicine, 5(34), p. 34. Springer Nature 10.1038/s41525-020-00141-0

Cismaru, Anca Liliana; Grimm, Livia; Rudin, Deborah; Ibañez, Luisa; Liakoni, Evangelia; Bonadies, Nicolas; Kreutz, Reinhold; Hallberg, Pär; Wadelius, Mia; Haschke, Manuel; Largiadèr, Carlo R.; Amstutz, Ursula (2020). High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis. Frontiers in genetics, 11(951), p. 951. Frontiers Media SA 10.3389/fgene.2020.00951

Wörmann, Bernhard; Bokemeyer, Carsten; Burmeister, Thomas; Köhne, Claus-Henning; Schwab, Matthias; Arnold, Dirk; Blohmer, Jens-Uwe; Borner, Markus; Brucker, Sara; Cascorbi, Ingolf; Decker, Thomas; de Wit, Maike; Dietz, Andreas; Einsele, Hermann; Eisterer, Wolfgang; Folprecht, Gunnar; Hilbe, Wolfgang; Hoffmann, Jürgen; Knauf, Wolfgang; Kunzmann, Volker; ... (2020). Dihydropyrimidine Dehydrogenase Testing prior to Treatment with 5-Fluorouracil, Capecitabine, and Tegafur: A Consensus Paper. Oncology research and treatment, 43(11), pp. 628-636. Karger 10.1159/000510258


van Dorland, Hendrika Anette; Mansouri Taleghani, Magnus; Sakai, Kazuya; Friedman, Kenneth D; George, James N; Hrachovinova, Ingrid; Knöbl, Paul N; von Krogh, Anne Sophie; Schneppenheim, Reinhard; Aebi-Huber, Isabella; Bütikofer, Lukas; Largiadèr, Carlo R.; Cermakova, Zuzana; Kokame, Koichi; Miyata, Toshiyuki; Yagi, Hideo; Terrell, Deirdra R; Vesely, Sara K; Matsumoto, Masanori; Lämmle, Bernhard; ... (2019). The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: Key findings at enrolment until 2017. Haematologica - the hematology journal, 104(10), pp. 2107-2115. Ferrata-Storti Foundation 10.3324/haematol.2019.216796

Freiburghaus, Katrin; Largiadèr, Carlo Rodolfo; Stettler, Christoph; Fiedler, Georg Martin; Bally, Lia; Bovet, Cédric (2019). Metabolomics by UHPLC-MS: benefits provided by complementary use of Q-TOF and QQQ for pathway profiling. Metabolomics, 15(9), p. 120. Springer 10.1007/s11306-019-1585-3

Kasapkara, Çigdem Seher; Nuoffer, Jean Marc; Baysoy, Gökhan; Aldudak, Bedri; Özbek, Mehmet Nuri; Akcaboy, Meltem; Largiadèr, Carlo R. (2019). Lethal Very Long-Chain Acyl-Coa Dehydrogenase Deficiency with A Novel Mutation. Gazi medical journal, 30(3), pp. 323-324. Gazi University Faculty of Medicine 10.12996/GMJ.2019.83


Amstutz, Ursula; Largiadèr, Carlo Rodolfo (2018). Genotype-guided fluoropyrimidine dosing: ready for implementation. The lancet oncology, 19(11), pp. 1421-1422. Elsevier 10.1016/S1470-2045(18)30744-7

Hamzic, Seid; Amstutz, Ursula; Largiadèr, Carlo Rodolfo (2018). Come a long way, still a ways to go: from predicting and preventing fluoropyrimidine toxicity to increased efficacy? Pharmacogenomics, 19(8), pp. 689-692. Future Medicine 10.2217/pgs-2018-0040

Amstutz, Ursula; Schärer, Dominic Manuel; Andrey, G; Wirthmüller, Urs; Largiadèr, Carlo Rodolfo (2018). An SSP-PCR method for the rapid detection of disease-associated alleles HLA-A*29 and HLA-B*51. HLA : immune response genetic, 92(2), pp. 90-93. Wiley 10.1111/tan.13296

Lesche, Dorothea; Sigurdardottir, Vilborg; Leichtle, Alexander Benedikt; Nakas, Christos T.; Christians, Uwe; Englberger, Lars; Fiedler, Georg Martin; Largiadèr, Carlo Rodolfo; Mohacsi, Paul; Sistonen, Johanna (2018). Targeted and global pharmacometabolomics in everolimus-based immunosuppression: association of co-medication and lysophosphatidylcholines with dose requirement. Metabolomics, 14(1), p. 3. Springer 10.1007/s11306-017-1294-8


Amstutz, Ursula; Grob, Tobias; Largiadèr, Carlo Rodolfo; Vassella, Erik (2017). Liquid Biopsy: Tumorgenetik in Körperflüssigkeiten. Pipette - Swiss laboratory medicine(6), pp. 11-12. EMH Schweizerischer Ärzteverlag AG

Zinkernagel, Martin; Zysset-Burri, Denise Corinne; Keller, Irene; Berger, Lieselotte Erika; Leichtle, Alexander Benedikt; Largiadèr, Carlo Rodolfo; Fiedler, Martin; Wolf, Sebastian (2017). Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration. Scientific Reports, 7(40826), p. 40826. Nature Publishing Group 10.1038/srep40826

Hamzic, Seid; Wenger, N; Fröhlich, Tanja; Joerger, M; Aebi, Stefan; Largiadèr, Carlo Rodolfo; Amstutz, Ursula (2017). The impact of ABCC11 polymorphisms on the risk of early-onset fluoropyrimidine toxicity. Pharmacogenomics journal, 17(4), pp. 319-324. Nature Publishing Group 10.1038/tpj.2016.23

Prost, Jean-Christophe; Brunner, Felix; Bovet, Cédric; Grob, Christian; Berchtold, Christian; Schlotterbeck, Götz; Kröll, Dino; Largiadèr, Carlo Rodolfo; Fiedler, Georg Martin; Juillerat, Pascal (2017). A UHPLC–MS/MS method for the quantification of 7α-hydroxy-4-cholesten-3-one to assist in diagnosis of bile acid malabsorption. Clinical mass spectrometry, 3, pp. 1-6. Elsevier 10.1016/j.clinms.2017.02.001

Hamzic, Seid; Kummer, Dominic; Milesi, S; Mueller, D; Joerger, M; Aebi, S; Amstutz, Ursula; Largiadèr, Carlo Rodolfo (2017). Novel Genetic Variants in Carboxylesterase 1 Predict Severe Early-Onset Capecitabine-Related Toxicity. Clinical pharmacology & therapeutics, 102(5), pp. 796-804. Wiley 10.1002/cpt.641

Bakker, Theo C. M.; Giger, Thomas; Frommen, Joachim Gerhard; Largiadèr, Carlo Rodolfo (2017). Rapid molecular sexing of three-spined sticklebacks, Gasterosteus aculeatus L., based on large Y-chromosomal insertions. Journal of applied genetics, 58(3), pp. 401-407. Springer 10.1007/s13353-017-0399-0


Kuilenburg, André B P van; Meijer, Judith; Tanck, Michael W T; Dobritzsch, Doreen; Zoetekouw, Lida; Dekkers, Lois-Lee; Roelofsen, Jeroen; Meinsma, Rutger; Wymenga, Machteld; Kulik, Wim; Büchel, Barbara; Hennekam, Raoul C M; Largiadèr, Carlo Rodolfo (2016). Phenotypic and clinical implications of variants in the dihydropyrimidine dehydrogenase gene. Biochimica et biophysica acta - molecular basis of disease, 1862(4), pp. 754-762. Elsevier 10.1016/j.bbadis.2016.01.009

Meulendijks, D; Henricks, LM; Amstutz, Ursula; Fröhlich, Tanja; Largiadèr, Carlo Rodolfo; Beijnen, JH; de Boer, A; Deenen, MJ; Cats, A; Schellens, JHM (2016). Rs895819 in MIR27A improves the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine-associated toxicity. International journal of cancer, 138(11), pp. 2752-2761. Wiley-Blackwell 10.1002/ijc.30014

von Krogh, A S; Quist-Paulsen, P; Waage, A; Langseth, Ø O; Thorstensen, K; Brudevold, R; Tjønnfjord, G E; Largiadèr, Carlo Rodolfo; Lämmle, Bernhard; Kremer Hovinga, Johanna Anna (2016). High prevalence of hereditary thrombotic thrombocytopenic purpura in Central Norway: from clinical observation to evidence. Journal of thrombosis and haemostasis, 14(1), pp. 73-82. Wiley-Blackwell 10.1111/jth.13186


Meulendijks, Didier; Henricks, Linda M.; Sonke, Gabe S.; Deenen, Maarten J.; Froehlich, Tanja K.; Amstutz, Ursula; Largiadèr, Carlo R.; Jennings, Barbara A.; Marinaki, Anthony M.; Sanderson, Jeremy D.; Kleibl, Zdenek; Kleiblova, Petra; Schwab, Matthias; Zanger, Ulrich M; Palles, Claire; Tomlinson, Ian; Gross, Eva; van Kuilenburg, André B. P.; Punt, Cornelis J. A.; Koopman, Miriam; ... (2015). Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data. The lancet oncology, 16(16), pp. 1639-1650. Elsevier 10.1016/S1470-2045(15)00286-7

Lesche, Dorothea; Sigurdardottir, Vilborg; Setoud, Raschid; Englberger, Lars; Fiedler, Georg M.; Largiadèr, Carlo R.; Mohacsi, Paul; Sistonen, Johanna (2015). Influence of CYP3A5 genetic variation on everolimus maintenance dosing after cardiac transplantation. Clinical transplantation, 29(12), pp. 1213-1220. Wiley-Blackwell 10.1111/ctr.12653

Kummer, Dominic; Fröhlich, Tanja; Joerger, Markus; Aebi, Stefan; Sistonen, Johanna; Amstutz, Ursula; Largiadèr, Carlo Rodolfo (2015). Dihydropyrimidinase and β-ureidopropionase gene variation and severe fluoropyrimidine-related toxicity. Pharmacogenomics, 16(12), pp. 1367-1377. Future Medicine 10.2217/pgs.15.81

Grandgirard, Denis; Furi, Leonardo; Ciusa, Maria Laura; Baldassarri, Lucilla; Knight, Daniel R; Morrissey, Ian; Largiadèr, Carlo Rodolfo; Leib, Stephen; Oggioni, Marco R (2015). Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression. BMC Genomics, 16(345), p. 345. BioMed Central 10.1186/s12864-015-1544-y

Amstutz, Ursula; Offer, Steven M; Sistonen, Johanna; Joerger, Markus; Diasio, Robert B; Largiadèr, Carlo Rodolfo (2015). Polymorphisms in MIR27A Associated with Early-Onset Toxicity in Fluoropyrimidine-Based Chemotherapy. Clinical cancer research, 21(9), pp. 2038-2044. American Association for Cancer Research 10.1158/1078-0432.CCR-14-2817

Fröhlich, Tanja; Amstutz, Ursula; Aebi, Stefan; Joerger, Markus; Largiadèr, Carlo Rodolfo (2015). Clinical importance of risk variants in the dihydropyrimidine dehydrogenase gene for the prediction of early-onset fluoropyrimidine toxicity. International journal of cancer, 136(3), pp. 730-739. Wiley-Blackwell 10.1002/ijc.29025

Gautschi, O.; Mach, N.; Rothschild, S.; Li, Qiyu; Stahel, R. A.; Zippelius, A.; Cathomas, R.; Früh, M.; Betticher, D. C.; Peters, S.; Rauch, D.; Feilchenfeldt, J.; Bubendorf, L.; Savic, S.; Jaggi, Rolf; Oppliger Leibundgut, Elisabeth; Largiadèr, Carlo Rodolfo; Brutsche, M.; Pilop, C.; Stalder, L.; ... (2015). Bevacizumab, Pemetrexed, and Cisplatin, or Bevacizumab and Erlotinib for Patients With Advanced Non-Small-Cell Lung Cancer Stratified by Epidermal Growth Factor Receptor Mutation: Phase II Trial SAKK19/09. Clinical lung cancer, 16(5), pp. 358-365. Elsevier 10.1016/j.cllc.2015.02.007


Lesche, Dorothea; Sigurdardottir, Vilborg; Setoud, Raschid; Oberhänsli, Markus; Carrel, Thierry; Fiedler, Georg M; Largiadèr, Carlo Rodolfo; Mohacsi, Paul; Sistonen, Johanna (2014). CYP3A5*3 and POR*28 genetic variants influence the required dose of tacrolimus in heart transplant recipients. Therapeutic drug monitoring, 36(6), pp. 710-715. Lippincott Williams & Wilkins 10.1097/FTD.0000000000000080

Sistonen, Johanna; Büchel, Barbara; Fröhlich, Tanja; Kummer, Dominic; Fontana, Stefano; Joerger, Markus; van Kuilenburg, André B P; Largiadèr, Carlo Rodolfo (2014). Predicting 5-fluorouracil toxicity: DPD genotype and 5,6-dihydrouracil:uracil ratio. Pharmacogenomics, 15(13), pp. 1653-1666. Future Medicine 10.2217/pgs.14.126

Al-Haggar, Mohammad; Largiadèr, Carlo Rodolfo; Abdel-Hady, Dina; Barakat, Tarik; Nuoffer, Jean-Marc; Al-Refaei, Abdel-Aziz (2014). Partial expression of ornithine transcarbamylase deficiency in an Egyptian female carrier. International journal of gynaecology and obstetrics, 124(2), pp. 174-175. Elsevier 10.1016/j.ijgo.2013.09.014


Yun, J,; Mattsson, J,; Schnyder, K,; Fontana, S,; Largiadèr, C, R,; Pichler, W, J,; Yerly, D, (2013). Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response. Clinical and experimental allergy, 43(11), pp. 1246-1255. Blackwell Scientific Publications 10.1111/cea.12184

Büchel, Barbara; Rhyn, Peter; Schürch, Stefan; Bühr, Claudia; Amstutz, Ursula; R Largiadèr, Carlo (2013). LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients. Biomedical chromatography, 27(1), pp. 7-16. Chichester: Wiley 10.1002/bmc.2741

Mueller, F; Büchel, B; Köberle, D; Schürch, Stefan; Pfister, B; Krähenbühl, St; Fröhlich, Tanja; Largiader, C R; Joerger, M (2013). Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study. Cancer chemotherapy and pharmacology, 71(2), pp. 361-70. Berlin: Springer 10.1007/s00280-012-2018-4

Büchel, Barbara; Sistonen, Johanna; Joerger, Markus; Aebi, Yolanda; Schürch, Stefan; Largiadèr, Carlo Rodolfo (2013). Comparative evaluation of the My5-FU™ immunoassay and LC-MS/MS in monitoring the 5-fluorouracil plasma levels in cancer patients. Clinical chemistry and laboratory medicine, 51(8), pp. 1681-1688. De Gruyter 10.1515/cclm-2012-0641


Vonlanthen, Pascal; Bittner, David; Hudson, Alan G; Young, Kyle A; Müller, Ruedi; Lundsgaard-Hansen, Bänz; Roy, Denis; di Piazza, Sacha; Largiadèr, Carlo Rodolfo; Seehausen, Ole (2012). Eutrophication causes speciation reversal in whitefish adaptive radiations. Nature, 482(7385), pp. 357-362. London: Macmillan Journals Ltd. 10.1038/nature10824

Sistonen, Johanna; Smith, Chingying; Fu, Yung-Kang; Largiadèr, Carlo R (2012). A new DPYD genotyping assay for improving the safety of 5-fluorouracil therapy. Clinica chimica acta, 414, pp. 109-111. Amsterdam: Elsevier 10.1016/j.cca.2012.08.015


Amstutz, Ursula; Andrey-Zürcher, Gisela; Suciu, Dominic; Jaggi, Rolf; Häberle, Johannes; Largiadèr, Carlo R (2011). Sequence capture and next-generation resequencing of multiple tagged nucleic acid samples for mutation screening of urea cycle disorders. Clinical chemistry, 57(1), pp. 102-11. Washington, D.C.: American Association for Clinical Chemistry 10.1373/clinchem.2010.150706

Amstutz, Ursula; Froehlich, Tanja K; Largiadèr, Carlo R (2011). Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity. Pharmacogenomics, 12(9), pp. 1321-36. London: Future Medicine 10.2217/PGS.11.72

Kuhn-Nentwig, Lucia; Largiadèr, Carlo R; Streitberger, Kathrin; Chandru, Sathyan; Baumann, Tommy; Kämpfer, Urs; Schaller, Johann; Schürch, Stefan; Nentwig, Wolfgang (2011). Purification, cDNA structure and biological significance of a single insulin-like growth factor-binding domain protein (SIBD-1) identified in the hemocytes of the spider Cupiennius salei. Insect biochemistry and molecular biology, 41(11), pp. 891-901. Amsterdam: Elsevier 10.1016/j.ibmb.2011.08.003

van Kuilenburg, André B P; Largiadèr, Carlo R (2011). SNPs and Haplotypes in DPYD and Outcome of Capecitabine-Letter. Clinical cancer research, 17(17), 5837; author reply 5835-6. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-11-1258

Bittner, David; Cossins, Andrew R; Segner, Helmut; Excoffier, Laurent; Largiadèr, Carlo R (2011). Identification of candidate genes and physiological pathways involved in gonad deformation in whitefish (Coregonus spp.) from Lake Thun, Switzerland. International journal of environmental research and public health, 8(7), pp. 2706-33. Basel: Molecular Diversity Preservation International MDPI 10.3390/ijerph8072706

Caudron, Arnaud; Champigneulle, Alexis; Guyomard, René; Largiadèr, Carlo (2011). Assessment of three strategies practiced by fishery managers for restoring native brown trout (Salmo trutta) populations in Northern French Alpine Streams. Ecology of freshwater fish, 20(3), pp. 478-491. Copenhagen: Munksgaard 10.1111/j.1600-0633.2010.00458.x


Ben-Ari, Ziv; Dalal, Adam; Morry, Ady; Pitlik, Silvio; Zinger, Pierre; Cohen, Jonathan; Fattal, Ittai; Galili-Mosberg, Ronit; Tessler, Debora; Baruch, Ruth Gershoni; Nuoffer, Jean-Marc; Largiader, Carlo R; Mandel, Hanna (2010). Adult-onset ornithine transcarbamylase (OTC) deficiency unmasked by the Atkins' diet. Journal of hepatology, 52(2), pp. 292-5. Amsterdam: Elsevier 10.1016/j.jhep.2009.11.014

Bittner, D; Excoffier, L; Largiadèr, C R (2010). Patterns of morphological changes and hybridization between sympatric whitefish morphs (Coregonus spp.) in a Swiss lake: a role for eutrophication? Molecular Ecology, 19(10), pp. 2152-67. Oxford: Wiley-Blackwell 10.1111/j.1365-294X.2010.04623.x

Baumann, Tommy; Kämpfer, Urs; Schürch, Stefan; Schaller, Johann; Largiadèr, Carlo; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia (2010). Ctenidins: antimicrobial glycine-rich peptides from the hemocytes of the spider Cupiennius salei. Cellular and molecular life sciences, 67(16), pp. 2787-2798. Basel: SP Birkhäuser Verlag Basel 10.1007/s00018-010-0364-0

Baumann, Tommy; Kuhn-Nentwig, Lucia; Largiadèr, Carlo R; Nentwig, Wolfgang (2010). Expression of defensins in non-infected araneomorph spiders. Cellular and molecular life sciences, 67(15), pp. 2643-51. Basel: SP Birkhäuser Verlag Basel 10.1007/s00018-010-0354-2


Vonlanthen, Pascal; Roy, Denis; Hudson, Alan; Largiadèr, Carlo Rodolfo; Bittner, David; Seehausen, Ole (2009). Divergence along a steep ecological gradient in lake whitefish (Coregonus sp.). Journal of Evolutionary Biology, 22(3), pp. 498-514. Basel: Wiley 10.1111/j.1420-9101.2008.01670.x

Horn, MP; Mäder-Heinemann, G; Andrey, G; Largiadèr, CR (2009). Mutation screening of the medium-chain acyl-CoA dehydrogenase (MCAD) and the ornithine transcarbamylase (OTC) genes by multiplex PCR amplification and sequencing. Clinical chemistry and laboratory medicine, 47(1), pp. 56-9. Berlin: Walter de Gruyter 10.1515/CCLM.2009.012

Bittner, D; Bernet, D; Wahli, Thomas; Segner, Helmut; Kueng, C; Largiadèr, Carlo R. (2009). How normal is abnormal? - Discriminating between deformations and natural variation in gonad morphology of European whitefish Coregonus lavaretus. Journal of fish biology, 74(7), pp. 1594-1614. Oxford: Blackwell 10.1111/j.1095-8649.2009.02233.x

Amstutz, U; Farese, S; Aebi, S; Largiadèr, CR (2009). Dihydropyrimidine dehydrogenase gene variation and severe 5-fluorouracil toxicity: A haplotype assessment. Pharmacogenomics, 10(6), pp. 931-944. London: Future Medicine 10.2217/PGS.09.28

Ketmaier, V; Finamore, F; Largiadèr, CR; Milone, M; Bianco, PG (2009). Phylogeography of bleaks (genus Alburnus, Cyprinidae) in Italy based on cytochrome b data. Journal of fish biology, 75(5), pp. 997-1017. Oxford: Blackwell 10.1111/j.1095-8649.2009.02357.x

Caudron, A; Champigneulle, A; Largiadèr, CR; Launey, S; Guyomard, R (2009). Stocking of native Mediterranean brown trout (Salmo trutta) into French tributaries of Lake Geneva does not contribute to lake-migratory spawners. Ecology of freshwater fish, 18(4), pp. 585-593. Copenhagen: Munksgaard 10.1111/j.1600-0633.2009.00374.x


Amstutz, Ursula; Farese, Simone; Aebi, Stefan; Largiadèr, Carlo R (2008). Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy. Clinical cancer research, 27, p. 54. Philadelphia, Pa.: American Association for Cancer Research 10.1186/1756-9966-27-54

Engel, Katharina; Nuoffer, Jean-Marc; Mühlhausen, Chris; Klaus, Vera; Largiadèr, Carlo R; Tsiakas, Konstantinos; Santer, René; Wermuth, Bendicht; Häberle, Johannes (2008). Analysis of mRNA transcripts improves the success rate of molecular genetic testing in OTC deficiency. Molecular genetics and metabolism, 94(3), pp. 292-7. Amsterdam: Elsevier 10.1016/j.ymgme.2008.03.009

Giger, Thomas; Excoffier, Laurent; Amstutz, Ursula; Day, Philip J R; Champigneulle, Alexis; Hansen, Michael M; Kelso, Janet; Largiadèr, Carlo R (2008). Population transcriptomics of life-history variation in the genus Salmo. Molecular Ecology, 17(13), pp. 3095-3108. Oxford: Wiley-Blackwell 10.1111/j.1365-294X.2008.03820.x

Neuenschwander, Samuel; Largiadèr, Carlo R; Ray, Nicolas; Currat, Mathias; Vonlanthen, Pascal; Excoffier, Laurent (2008). Colonization history of the Swiss Rhine basin by the bullhead (Cottus gobio): inference under a Bayesian spatially explicit framework. Molecular Ecology, 17(3), pp. 757-772. Oxford: Wiley-Blackwell 10.1111/j.1365-294X.2007.03621.x


Vonlanthen, Pascal; Excoffier, Laurent; Bittner, David; Persat, H; Neuenschwander, S; Largiadèr, Carlo (2007). Genetic analysis of potential postglacial watershed crossings in central Europe by the bullhead (Cottus gobio L). Molecular Ecology, 16(21), pp. 4572-4584. Oxford: Wiley-Blackwell 10.1111/j.1365-294X.2007.03531.x

Zbinden, Judith; Largiadèr, Carlo; Leippert, Fabio; Margaritoulis, Dimitris; Arlettaz, Raphaël (2007). High frequency of multiple paternity in the largest rookery of Mediterranean loggerhead sea turtles. Molecular Ecology, 16(17), pp. 3703-3711. Oxford: Wiley-Blackwell 10.1111/j.1365-294X.2007.03426.x

Giger, Thomas; Amstutz, Ursula; Excoffier, Laurent; Champigneulle, Alexis; Day, Philip; Powell, Richard; Largiadèr, Carlo (2007). The genetic basis of smoltification: Functional genomics tools facilitate the search for the needle in the haystack. In: Harris, Graeme; Millner, Nigel (eds.) Sea Trout: Biology Conservation and Management (pp. 183-195). Chichester: John Wiley & Sons 10.1002/9780470996027.ch13

Largiadèr, Carlo Rodolfo (2007). Hybridization and Introgression Between Native and Alien Species. In: Nentwig, Wolfgang (ed.) Biological Invasions. Ecological Studies: Vol. 193 (pp. 275-292). Heidelberg: Springer 10.1007/978-3-540-36920-2_16


Giger, Thomas; Excoffier, Laurent; Day, Philip J R; Champigneulle, Alexis; Hansen, Michael M; Powell, Richard; Largiadèr, Carlo R (2006). Life history shapes gene expression in salmonids. Current Biology, 16(8), R281-R282. Cambridge, Mass.: Cell Press 10.1016/j.cub.2006.03.053

Bakker, Theo C M; Zbinden, Marc; Frommen, Joachim G; Weiss, Alexander; Largiadèr, Carlo R (2006). Slow fertilization of stickleback eggs: the result of sexual conflict? BMC ecology, 6, p. 7. London: BioMed Central 10.1186/1472-6785-6-7

Amstutz, U; Giger, T; Champigneulle, A; Day, PJR; Largiader, CR (2006). Distinct temporal patterns of transaldolase 1 gene expression in future migratory and sedentary brown trout (Salmo trutta). Aquaculture, 1-4(260), j. Amsterdam: Elsevier 10.1016/j.aquaculture.2006.06.007

Caudron, A; Champigneulle, A; Largiadèr, CR; Guyomard, R (2006). Bilan des Conaissance en Début 2003 et Cadrage du Programme. In: Programme INTERREG III A- Identification sauvegarde et réhabilitation des populations de truite autochthones en Vallée d Aoste et en Haute-Savoie. Milano: Jona Srl - Paderno Dugnano


Zbinden, Marc; Largiadèr, Carlo R.; Bakker, Theo C. M. (2004). Body size of virtual rivals affects ejaculate size in sticklebacks. Behavioral Ecology, 15(1), pp. 137-140. Oxford University Press 10.1093/beheco/arg110


Nicod, Jean‐Claude; Largiadèr, Carlo R. (2003). SNPs by AFLP (SBA): a rapid SNP isolation strategy for non‐model organisms. Nucleic acids research, 31(5), 19e-19. Oxford University Press 10.1093/nar/gng019

Zbinden, Marc; Mazzi, Dominique; Künzler, Reto; Largiadèr, Carlo R.; Bakker, Theo C. M. (2003). Courting virtual rivals increase ejaculate size in sticklebacks (Gasterosteus aculeatus). Behavioral ecology and sociobiology, 54(3), pp. 205-209. Springer-Verlag 10.1007/s00265-003-0612-5

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