V'kovski, Philip

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2023

Probst, Lukas; Laloli, Laura; Licheri, Manon Flore; Licheri, Matthias; Gultom, Mitra; Holwerda, Melle; V'kovski, Philip; Dijkman, Ronald (2023). Generation and Characterization of an Influenza D Reporter Virus. Viruses, 15(12), p. 2444. MDPI 10.3390/v15122444

2022

Kelly, Jenna N; Laloli, Laura; V'kovski, Philip; Holwerda, Melle; Portmann, Jasmine; Thiel, Volker; Dijkman, Ronald (2022). Comprehensive single cell analysis of pandemic influenza A virus infection in the human airways uncovers cell-type specific host transcriptional signatures relevant for disease progression and pathogenesis. Frontiers in immunology, 13(978824), p. 978824. Frontiers Research Foundation 10.3389/fimmu.2022.978824

Laloli, Laura; Licheri, Manon Flore; Probst, Lukas; Licheri, Matthias; Gultom, Mitra; Holwerda, Melle; V'kovski, Philip; Dijkman, Ronald (2022). Time-resolved characterization of the innate immune response in the respiratory epithelium of human, porcine, and bovine during influenza virus infection. Frontiers in immunology, 13, p. 970325. Frontiers Research Foundation 10.3389/fimmu.2022.970325

2021

Kratzel, Annika; Kelly, Jenna N; V'kovski, Philip; Portmann, Jasmine; Brüggemann, Yannick; Todt, Daniel; Ebert, Nadine; Shrestha, Neeta; Plattet, Philippe; Staab-Weijnitz, Claudia A; von Brunn, Albrecht; Steinmann, Eike; Dijkman, Ronald; Zimmer, Gert; Pfaender, Stephanie; Thiel, Volker (2021). A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets. PLoS biology, 19(12), e3001490. Public Library of Science 10.1371/journal.pbio.3001490

Tabata, Keisuke; Prasad, Vibhu; Paul, David; Lee, Ji-Young; Pham, Minh-Tu; Twu, Woan-Ing; Neufeldt, Christopher J; Cortese, Mirko; Cerikan, Berati; Stahl, Yannick; Joecks, Sebastian; Tran, Cong Si; Lüchtenborg, Christian; V'kovski, Philip; Hörmann, Katrin; Müller, André C; Zitzmann, Carolin; Haselmann, Uta; Beneke, Jürgen; Kaderali, Lars; ... (2021). Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation. Nature Communications, 12(1), p. 7276. Springer Nature 10.1038/s41467-021-27511-1

Gultom, Mitra; Licheri, Matthias; Laloli, Laura; Wider, Manon; Strässle, Marina; V'kovski, Philip; Steiner, Silvio; Kratzel, Annika; Tran, Thi Nhu Thao; Probst, Lukas; Stalder, Hanspeter; Portmann, Jasmine; Holwerda, Melle; Ebert, Nadine; Stokar-Regenscheit, Nadine; Gurtner, Corinne; Zanolari, Patrik; Posthaus, Horst; Schuller, Simone; Vicente-Santos, Amanda; ... (2021). Susceptibility of Well-Differentiated Airway Epithelial Cell Cultures from Domestic and Wild Animals to Severe Acute Respiratory Syndrome Coronavirus 2. Emerging infectious diseases, 27(7), pp. 1811-1820. Centers for Disease Control and Prevention 10.3201/eid2707.204660

Strässle, Marina; Laloli, Laura; Gultom, Mitra; V'kovski, Philip; Stoffel, Michael H.; Crespo Pomar, Silvia; Chanfon Bätzner, Astrid; Ebert, Nadine; Labroussaa, Fabien; Dijkman, Ronald; Jores, Joerg; Thiel, Volker (2021). Establishment of caprine airway epithelial cells grown in an air-liquid interface system to study caprine respiratory viruses and bacteria. Veterinary microbiology, 257, p. 109067. Elsevier 10.1016/j.vetmic.2021.109067

Garcia Nicolas, Obdulio; V'kovski, Philip; Zettl, Ferdinand; Zimmer, Gert; Thiel, Volker; Summerfield, Artur (2021). No Evidence for Human Monocyte-Derived Macrophage Infection and Antibody-Mediated Enhancement of SARS-CoV-2 Infection. Frontiers in cellular and infection microbiology, 11(644574), p. 644574. Frontiers 10.3389/fcimb.2021.644574

V'kovski, Philip; Gultom, Mitra; Kelly, Jenna N.; Steiner, Silvio; Russeil, Julie; Mangeat, Bastien; Cora, Elisa; Pezoldt, Joern; Holwerda, Melle; Kratzel, Annika; Laloli, Laura; Wider, Manon; Portmann, Jasmine; Tran, Thao; Ebert, Nadine; Stalder, Hanspeter; Hartmann, Rune; Gardeux, Vincent; Alpern, Daniel; Deplancke, Bart; ... (2021). Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium. PLoS biology, 19(3), e3001158. Public Library of Science 10.1371/journal.pbio.3001158

V'kovski, Philip; Kratzel, Annika; Steiner, Silvio; Stalder, Hanspeter; Thiel, Volker (2021). Coronavirus biology and replication: implications for SARS-CoV-2. Nature reviews. Microbiology, 19(3), pp. 155-170. Springer Nature 10.1038/s41579-020-00468-6

2020

Gasbarri, Matteo; V'kovski, Philip; Torriani, Giulia; Thiel, Volker; Stellacci, Francesco; Tapparel, Caroline; Cagno, Valeria (2020). SARS-CoV-2 Inhibition by Sulfonated Compounds. Microorganisms, 8(12) MDPI 10.3390/microorganisms8121894

Holwerda, Melle; V'kovski, Philip; Wider, Manon; Thiel, Volker; Dijkman, Ronald (2020). Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In Vitro. Microorganisms, 8(12) MDPI 10.3390/microorganisms8121872

Pfaender, Stephanie; Mar, Katrina B; Michailidis, Eleftherios; Kratzel, Annika; Boys, Ian N; V'kovski, Philip; Fan, Wenchun; Kelly, Jenna N.; Hirt, Dagny; Ebert, Nadine; Stalder, Hanspeter; Kleine-Weber, Hannah; Hoffmann, Markus; Heinrich Hoffmann, H; Saeed, Mohsan; Dijkman, Ronald; Steinmann, Eike; Wight-Carter, Mary; McDougal, Matthew B; Hanners, Natasha W; ... (2020). LY6E impairs coronavirus fusion and confers immune control of viral disease. Nature microbiology, 5(11), pp. 1330-1339. Springer Nature 10.1038/s41564-020-0769-y

Kratzel, Annika; Steiner, Silvio; Todt, Daniel; V'kovski, Philip; Brueggemann, Yannick; Steinmann, Joerg; Steinmann, Eike; Thiel, Volker; Pfaender, Stephanie (2020). Temperature-dependent surface stability of SARS-CoV-2. Journal of infection, 81(3), pp. 452-482. Elsevier 10.1016/j.jinf.2020.05.074

Zettl, Ferdinand; Meister, Toni Luise; Vollmer, Tanja; Fischer, Bastian; Steinmann, Jörg; Krawczyk, Adalbert; V'kovski, Philip; Todt, Daniel; Steinmann, Eike; Pfaender, Stephanie; Zimmer, Gert (2020). Rapid Quantification of SARS-CoV-2-Neutralizing Antibodies Using Propagation-Defective Vesicular Stomatitis Virus Pseudotypes. Vaccines, 8(3) MDPI 10.3390/vaccines8030386

Kratzel, Annika; Todt, Daniel; V'kovski, Philip; Steiner, Silvio; Gultom, Mitra; Tran, Thi Nhu Thao; Ebert, Nadine; Holwerda, Melle; Steinmann, Jörg; Niemeyer, Daniela; Dijkman, Ronald; Kampf, Günter; Drosten, Christian; Steinmann, Eike; Thiel, Volker; Pfaender, Stephanie (2020). Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols. Emerging infectious diseases, 26(7), pp. 1592-1595. Centers for Disease Control and Prevention 10.3201/eid2607.200915

Tran, Thi Nhu Thao; Labroussaa, Fabien; Ebert, Nadine; V'kovski, Philip; Stalder, Hanspeter; Portmann, Jasmine; Kelly, Jenna; Steiner, Silvio; Holwerda, Melle; Kratzel, Annika; Gultom, Mitra; Schmied, Kimberly; Laloli, Laura; Hüsser, Linda; Wider, Manon; Pfaender, Stephanie; Hirt, Dagny; Cippà, Valentina; Crespo-Pomar, Silvia; Schröder, Simon; ... (2020). Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature, 582(7813), pp. 561-565. Springer Nature 10.1038/s41586-020-2294-9

Cong, Yingying; Ulasli, Mustafa; Schepers, Hein; Mauthe, Mario; V'kovski, Philip; Kriegenburg, Franziska; Thiel, Volker; de Haan, Cornelis A M; Reggiori, Fulvio (2020). Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle. Journal of virology, 94(4) American Society for Microbiology 10.1128/JVI.01925-19

V'kovski, Philip; Steiner, Silvio; Thiel, Volker (2020). Proximity Labeling for the Identification of Coronavirus-Host Protein Interactions. Methods in molecular biology, 2203, pp. 187-204. Springer 10.1007/978-1-0716-0900-2_14

2019

V'kovski, Philip; Gerber, Markus; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga Lagache, Sophie; Simillion, Cedric; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (2019). Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling. eLife, 8 eLife Sciences Publications 10.7554/eLife.42037

2018

Garcia Nicolas, Obdulio; V'kovski, Philip; Vielle, Nathalie J.; Ebert, Nadine; Züst, R; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Vieyres, G; Stoffel, Michael; Schweizer, Matthias; Summerfield, Artur; Engler, O; Pietschmann, T; Todt, D; Alves, Marco; Thiel, Volker; Pfänder, Stephanie (2018). The small compound inhibitor K22 displays broad antiviral activity against different members of the family Flaviviridae and offers potential as pan-viral inhibitor. Antimicrobial agents and chemotherapy, 62(11) American Society for Microbiology 10.1128/AAC.01206-18

V'kovski, Philip; Gerber, M; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga, Sophie Marie-Pierre; Simillion, Cedric André Marie; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (14 September 2018). Determination of host cell proteins constituting the molecular microenvironment of coronavirus replicase complexes by proximity-labeling (bioRxiv). Cold Spring Harbor Laboratory 10.1101/417907

Milewska, Aleksandra; Kindler, Eveline Patricia; V'Kovski, Philip; Zeglen, S; Ochman, M; Thiel, Volker Earl; Rajfur, Z; Pyrc, K (2018). APOBEC3-mediated restriction of RNA virus replication. Scientific Reports, 8(1), p. 5960. Nature Publishing Group 10.1038/s41598-018-24448-2

Rappe, Julie Christiane Françoise; de Wilde, Adriaan; Di, Han; Müller, Christin; Stalder, Hanspeter; V'Kovski, Philip; Snijder, Eric; Brinton, Margo A; Ziebuhr, John; Ruggli, Nicolas; Thiel, Volker Earl (2018). Antiviral activity of K22 against members of the order Nidovirales. Virus research, 246, pp. 28-34. Elsevier 10.1016/j.virusres.2018.01.002

2017

Kindler, Eveline Patricia; Gil-Cruz, Cristina; Spanier, Julia; Li, Yize; Wilhelm, Jochen; Rabouw, Huib H; Züst, Roland; Hwang, Mihyun; V'Kovski, Philip; Stalder, Hanspeter; Marti, Sabrina; Habjan, Matthias; Cervantes-Barragan, Luisa; Elliot, Ruth; Karl, Nadja; Gaughan, Christina; van Kuppeveld, Frank J M; Silverman, Robert H; Keller, Markus; Ludewig, Burkhard; ... (2017). Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS pathogens, 13(2), e1006195. Public Library of Science 10.1371/journal.ppat.1006195

2015

V'Kovski, Philip; Al-Mulla, Hawaa; Thiel, Volker Earl; Neuman, Benjamin W (2015). New insights on the role of paired membrane structures in coronavirus replication. Virus research, 202, pp. 33-40. Elsevier 10.1016/j.virusres.2014.12.021

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