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Coukos, Alexander; Saglietti, Chiara; Sempoux, Christine; Haubitz, Monika; Greuter, Thomas; Mittaz-Crettol, Laureane; Maurer, Fabienne; Mdawar-Bailly, Elise; Moradpour, Darius; Alberio, Lorenzo; Good, Jean-Marc; Baerlocher, Gabriela M; Fraga, Montserrat (2024). High prevalence of short telomeres in idiopathic porto-sinusoidal vascular disorder. Hepatology communications, 8(8) Wolters Kluwer Health 10.1097/HC9.0000000000000500
Pereira Portela, Cindy; Gautier, Lucas A; Zermatten, Maxime G; Fraga, Montserrat; Moradpour, Darius; Bertaggia Calderara, Debora; Aliotta, Alessandro; Veuthey, Lucas; De Gottardi, Andrea; Stirnimann, Guido; Alberio, Lorenzo (2024). Direct oral anticoagulants in cirrhosis: Rationale and current evidence. JHEP reports, 6(8), p. 101116. Elsevier 10.1016/j.jhepr.2024.101116
Radu, Pompilia; Becchetti, Chiara; Schropp, Jonas; Schmid, Patrick; Künzler-Heule, Patrizia; Mertens, Joachim; Moradpour, Darius; Müllaupt, Beat; Semela, David; Negro, Francesco; Heim, Markus; Clerc, Olivier; Roelens, Maroussia; Keiser, Olivia; Berzigotti, Annalisa (2024). Effect of Direct Acting Antiviral Drugs on the Occurrence and Recurrence of Intra- and Extra-Hepatic Malignancies in Patients with Chronic Hepatitis C Virus Infection. Cancers, 16(14) MDPI AG 10.3390/cancers16142573
Roelens, Maroussia; Bertisch, Barbara; Moradpour, Darius; Cerny, Andreas; Semmo, Nasser; Schmid, Patrick; Mülhaupt, Beat; Clerc, Olivier; Semela, David; Junker, Christoph; Negro, Francesco; Keiser, Olivia; Hepatitis C Cohort Study, Swiss (2020). All-Cause Mortality and Causes of Death in the Swiss Hepatitis C Cohort Study (SCCS). Open Forum Infectious Diseases, 7(8), ofaa308. Oxford University Press 10.1093/ofid/ofaa308
Moschouri, Eleni; Vionnet, Julien; Giostra, Emiliano; Daccord, Cécile; Lazor, Romain; Sciarra, Amedeo; Letovanec, Igor; Sempoux, Christine; Gonzalez, Michel; Unger, Sheila; Fodstad, Heidi; Haubitz, Monika; Baerlocher, Gabriela M.; Voruz, Sophie; Naveiras, Olaia; Jacquemin, Emmanuel; Moradpour, Darius; Fraga, Montserrat (2020). Combined Lung and Liver Transplantation for Short Telomere Syndrome. Liver transplantation, 26(6), pp. 840-844. Wiley 10.1002/lt.25734
Zermatten, Maxime G; Fraga, Montserrat; Moradpour, Darius; Bertaggia Calderara, Debora; Aliotta, Alessandro; Stirnimann, Guido; De Gottardi, Andrea; Alberio, Lorenzo (2020). Hemostatic Alterations in Patients With Cirrhosis: From Primary Hemostasis to Fibrinolysis. Hepatology, 71(6), pp. 2135-2148. Wiley Interscience 10.1002/hep.31201
Bertisch, Barbara; Brezzi, Matteo; Negro, Francesco; Müllhaupt, Beat; Ottiger, Cornelia; Künzler-Heule, Patrizia; Schmid, Patrick; Giudici, Fabio; Clerc, Olivier; Moriggia, Alberto; Roelens, Maroussia; Marinucci, Francesco; Zehnder, Cinzia; Moradpour, Darius; Keiser, Olivia (2020). Very low hepatitis C viral loads in treatment-naïve persons: do they compromise hepatitis C virus antigen testing? Clinical infectious diseases, 70(4), pp. 653-659. The University of Chicago Press 10.1093/cid/ciz270
Terziroli Beretta-Piccoli, Benedetta; Di Bartolomeo, Claudia; Deleonardi, Gaia; Grondona, Ana Gabriela; Silvestri, Tania; Tesei, Cinzia; Melidona, Laura; Cerny, Andreas; Mertens, Joachim; Semmo, Nasser; Semela, David; Moradpour, Darius; Mieli-Vergani, Giorgina; Vergani, Diego; Muratori, Luigi (2019). Autoimmune liver serology before and after successful treatment of chronic hepatitis C by direct acting antiviral agents. Journal of autoimmunity, 102, pp. 89-95. Elsevier 10.1016/j.jaut.2019.04.019
Asgari, Samira; Chaturvedi, Nimisha; Scepanovic, Petar; Hammer, Christian; Semmo, Nasser; Giostra, Emiliano; Müllhaupt, Beat; Angus, Peter; Thompson, Alexander J; Moradpour, Darius; Fellay, Jacques (2019). Human genomics of acute liver failure due to hepatitis B virus infection: An exome sequencing study in liver transplant recipients. Journal of viral hepatitis, 26(2), pp. 271-277. Wiley 10.1111/jvh.13019
Brezzi, Matteo; Bertisch, Barbara; Roelens, Maroussia; Moradpour, Darius; Terziroli Beretta-Piccoli, Benedetta; Semmo, Nasser; Müllhaupt, Beat; Semela, David; Negro, Francesco; Keiser, Olivia (2019). Impact of geographic origin on access to therapy and therapy outcomes in the Swiss Hepatitis C Cohort Study. PLoS ONE, 14(6), e0218706. Public Library of Science 10.1371/journal.pone.0218706
Gauthiez, Emeline; Habfast-Robertson, Ines; Rüeger, Sina; Kutalik, Zoltan; Aubert, Vincent; Berg, Thomas; Cerny, Andreas; Gorgievski, Meri; George, Jacob; Heim, Markus H; Malinverni, Raffaele; Moradpour, Darius; Müllhaupt, Beat; Negro, Francesco; Semela, David; Semmo, Nasser; Villard, Jean; Bibert, Stéphanie; Bochud, Pierre-Yves (2017). A systematic review and meta-analysis of HCV clearance. Liver international, 37(10), pp. 1431-1445. Wiley 10.1111/liv.13401
Béguelin, Charles Antoine; Friolet, Nicole; Moradpour, Darius; Sahli, Roland; Suter, Franziska Marta; Lüthi, Alexander; Cavassini, Matthias; Günthard, Huldrych F; Battegay, Manuel; Bernasconi, Enos; Schmid, Patrick; Calmy, Alexandra; Atkinson, Andrew; Rauch, Andri; Wandeler, Gilles (2017). Impact of tenofovir on hepatitis delta virus replication in the Swiss HIV Cohort Study. Clinical infectious diseases, 64(9), pp. 1275-1278. Oxford University Press 10.1093/cid/cix125
Ambregna, Sylvain; Koch, Stéphane; Sulz, Michael C; Grüner, Beate; Öztürk, Sümeyra; Chevaux, Jean-Baptiste; Sulima, Małgorzata; De Gottardi, Andrea; Napoléon, Bertrand; Abergel, Armand; Bichard, Philippe; Boytchev, Isabelle; Deprez, Pierre; Dumortier, Jerome; Frossard, Jean-Louis; Kull, Eric; Meny, Bernard; Moradpour, Darius; Prat, Fréderic; Vanbiervliet, Geoffroy; ... (2017). A European survey of perendoscopic treatment of biliary complications in patients with alveolar echinococcosis. Expert review of anti-infective therapy, 15(1), pp. 79-88. Expert Reviews 10.1080/14787210.2017.1252260
Fraga, Montserrat; Fournier, Nicolas; Safroneeva, Ekaterina; Pittet, Valérie; Godat, Sébastien; Straumann, Alex; Nydegger, Andreas; Vavricka, Stephan R; Moradpour, Darius; Schoepfer, Alain M (2017). Primary sclerosing cholangitis in the Swiss Inflammatory Bowel Disease Cohort Study: prevalence, risk factors, and long-term follow-up. European journal of gastroenterology & hepatology, 29(1), pp. 91-97. Lippincott Williams & Wilkins 10.1097/MEG.0000000000000747
Béguelin, Charles Antoine; Moradpour, Darius; Sahli, Roland; Suter, Franziska Marta; Lüthi, Alexander; Cavassini, Matthias; Günthard, Huldrych F; Battegay, Manuel; Bernasconi, Enos; Schmid, Patrick; Calmy, Alexandra; Braun, Dominique; Furrer, Hansjakob; Rauch, Andri; Wandeler, Gilles (2017). Hepatitis delta-associated mortality in HIV/HBV-coinfected patients. Journal of hepatology, 66(2), pp. 297-303. Elsevier 10.1016/j.jhep.2016.10.007
Bertisch, Barbara; Giudici, Fabio; Negro, Francesco; Moradpour, Darius; Müllhaupt, Beat; Moriggia, Alberto; Estill, Janne; Keiser, Olivia (2016). Characteristics of Foreign-Born Persons in the Swiss Hepatitis C Cohort Study: Implications for Screening Recommendations. PLoS ONE, 11(5), e0155464. Public Library of Science 10.1371/journal.pone.0155464
Winter, Annja; Letang, Emilio; Kalinjuma, Aneth Vedastus; Kimera, Namvua; Ntamatungiro, Alex; Glass, Tracy; Moradpour, Darius; Sahli, Roland; Le Gal, Frédéric; Furrer, Hansjakob; Wandeler, Gilles (2016). Absence of Hepatitis Delta Infection in a Large Rural HIV Cohort in Tanzania. International journal of infectious diseases, 46, pp. 8-10. Elsevier 10.1016/j.ijid.2016.03.011
Béguelin, Charles Antoine; Vázquez, Miriam; Moradpour, Darius; Sahli, Roland; Suter, Franziska Marta; Rauch, Andri; Wandeler, Gilles (2016). Uncontrolled hepatitis delta virus infection after initial suppression on tenofovir in a HIV/HBV-coinfected patient. AIDS, 30(3), pp. 530-533. Lippincott Williams & Wilkins 10.1097/QAD.0000000000000972
Béguelin, Charles Antoine; Montserrat, Fraga; Wandeler, Gilles; Sahli, Roland; Rauch, Andri; Moradpour, Darius (2016). Hepatitis E. Swiss medical forum, 16(24), pp. 510-514. EMH Schweizerischer Ärzteverlag AG
Terczyńska-Dyla, Ewa; Bibert, Stephanie; Duong, Francois H T; Krol, Ilona; Jørgensen, Sanne; Collinet, Emilie; Kutalik, Zoltán; Aubert, Vincent; Cerny, Andreas; Kaiser, Laurent; Malinverni, Raffaele; Mangia, Alessandra; Moradpour, Darius; Müllhaupt, Beat; Negro, Francesco; Santoro, Rosanna; Semela, David; Semmo, Nasser; Heim, Markus H; Bochud, Pierre-Yves; ... (2015). Corrigendum: reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes. Nature communications, 6, p. 7280. Nature Publishing Group 10.1038/ncomms8280
Frei, Pascal; Leucht, Anna-Kathrin; Held, Ulrike; Kofmehl, Reto; Manser, Christine N.; Schmitt, Johannes; Mertens, Joachim; Rau, Monika; Baur, Katharina; Gerlach, Tilman; Negro, Francesco; Heim, Markus; Moradpour, Darius; Cerny, Andreas; Dufour, Jean-François; Müllhaupt, Beat; Geier, Andreas (2014). Elderly age is not a negative predictive factor for virological response to therapy with pegylated interferon-α and ribavirin in chronic hepatitis C virus patients. Liver international, 34(4), pp. 551-557. Blackwell Munksgaard 10.1111/liv.12279
Terczyńska-Dyla, Ewa; Bibert, Stephanie; Duong, Francois H. T.; Krol, Ilona; Jørgensen, Sanne; Collinet, Emilie; Kutalik, Zoltán; Aubert, Vincent; Cerny, Andreas; Kaiser, Laurent; Malinverni, Raffaele; Mangia, Alessandra; Moradpour, Darius; Müllhaupt, Beat; Negro, Francesco; Santoro, Rosanna; Semela, David; Semmo, Nasser; Rubbia-Brandt, Laura; Martinetti, Gladys; ... (2014). Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes. Nature communications, 5, p. 5699. Nature Publishing Group 10.1038/ncomms6699
Morard, Isabelle; Clément, Sophie; Calmy, Alexandra; Mangia, Alessandra; Cerny, Andrea; De Gottardi, Andrea; Gorgievski, Meri; Heim, Markus; Malinverni, Raffaele; Moradpour, Darius; Müllhaupt, Beat; Semela, David; Pascarella, Stéphanie; Bochud, Pierre-Yves; Negro, Franco (2014). Clinical significance of the CCR5delta32 allele in hepatitis C. PLoS ONE, 9(9), e106424. Public Library of Science 10.1371/journal.pone.0106424
Bibert, Stéphanie; Roger, Thierry; Calandra, Thierry; Bochud, Murielle; Cerny, Andreas; Semmo, Nasser; Duong, François H. T.; Gerlach, Tilman; Malinverni, Raffaele; Moradpour, Darius; Negro, Francesco; Müllhaupt, Beat; Bochud, Pierre-Yves; Swiss Hepatitis C Cohort Study, the; Dufour, Jean-François (2013). IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction. Journal of experimental medicine, 210(6), pp. 1109-1116. Rockefeller University Press 10.1084/jem.20130012
Rau, Monika; Stickel, Felix; Russmann, Stefan; Manser, Christine N; Becker, Philip P; Weisskopf, Michael; Schmitt, Johannes; Dill, Michael T; Dufour, Jean-François; Moradpour, Darius; Semela, David; Müllhaupt, Beat; Geier, Andreas; Swiss Hepatitis C Cohort Study Group (SCCS), (2013). Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection. Journal of hepatology, 58(4), pp. 669-75. Amsterdam: Elsevier 10.1016/j.jhep.2012.11.027
Stickel, Felix; Worni, Mathias; Pache, Isabelle; Moradpour, Darius; Helbling, Beat; Borovicka, Jan; Gerlach, Tilman J (2013). Optimizing Ribavirin Exposure by Therapeutic Drug Monitoring Improves Treatment Response in Patients With Chronic Hepatitis C Genotype 1. American journal of gastroenterology, 108(7), pp. 1176-1178. Nature 10.1038/ajg.2013.140
Lange, Christian M.; Miki, Daiki; Ochi, Hidenori; Nischalke, Hans-Dieter; Bojunga, Jörg; Bibert, Stéphanie; Morikawa, Kenichi; Gouttenoire, Jérôme; Cerny, Andreas; Dufour, Jean-François; Gorgievski, Meri; Heim, Markus H.; Malinverni, Raffaele; Müllhaupt, Beat; Negro, Francesco; Semela, David; Kutalik, Zoltan; Müller, Tobias; Spengler, Ulrich; Berg, Thomas; ... (2013). Genetic Analyses Reveal a Role for Vitamin D Insufficiency in HCV-Associated Hepatocellular Carcinoma Development. PLoS ONE, 8(5), e64053. Public Library of Science 10.1371/journal.pone.0064053
Lange, Christian M.; Bibert, Stéphanie; Dufour, Jean-François; Cellerai, Cristina; Cerny, Andreas; Heim, Markus H.; Kaiser, Laurent; Malinverni, Raffaele; Müllhaupt, Beat; Negro, Francesco; Semela, David; Moradpour, Darius; Kutalik, Zoltán; Bochud, Pierre-Yves (2013). Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma. Journal of hepatology, 59(3), pp. 504-509. Elsevier 10.1016/j.jhep.2013.04.032
Bochud, Pierre-Yves; Bibert, Stéphanie; Kutalik, Zoltán; Patin, Etienne; Guergnon, Julien; Nalpas, Bertrand; Goossens, Nicolas; Kuske, Lorenz; Müllhaupt, Beat; Gerlach, Tillman; Heim, Markus H; Moradpour, Darius; Cerny, Andreas; Malinverni, Raffaele; Regenass, Stephan; Dollenmaier, Guenter; Hirsch, Hans; Martinetti, Gladys; Gorgiewski, Meri; Bourlière, Marc; ... (2012). IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes. Hepatology, 55(2), pp. 384-94. Hoboken, N.J.: Wiley Interscience 10.1002/hep.24678
Kuske, Lorenz; Mensen, Armand; Müllhaupt, Beat; Negro, Francesco; Semela, David; Moradpour, Darius; Malé, Pierre Jean; Heim, Markus H; Malinverni, Raffaele; Cerny, Andreas; Dufour, Jean-François; Swiss Hepatitis C Cohort Study, (2012). Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma. Swiss medical weekly, 142, w13651. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2012.13651
Patin, Etienne; Kutalik, Zoltán; Guergnon, Julien; Bibert, Stéphanie; Nalpas, Bertrand; Jouanguy, Emmanuelle; Munteanu, Mona; Bousquet, Laurence; Argiro, Laurent; Halfon, Philippe; Boland, Anne; Müllhaupt, Beat; Semela, David; Dufour, Jean-François; Heim, Markus H; Moradpour, Darius; Cerny, Andreas; Malinverni, Raffaele; Hirsch, Hans; Martinetti, Gladys; ... (2012). Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology, 143(5), 1244-52.e1-12. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2012.07.097
Lange, Christian M; Bibert, Stephanie; Kutalik, Zoltan; Burgisser, Philippe; Cerny, Andreas; Dufour, Jean-François; Geier, Andreas; Gerlach, Tilman J; Heim, Markus H; Malinverni, Raffaele; Negro, Francesco; Regenass, Stephan; Badenhoop, Klaus; Bojunga, Jörg; Sarrazin, Christoph; Zeuzem, Stefan; Müller, Tobias; Berg, Thomas; Bochud, Pierre-Yves; Moradpour, Darius; ... (2012). A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C. PLoS ONE, 7(7), e40159. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0040159
Lange, Christian M; Kutalik, Zoltan; Morikawa, Kenichi; Bibert, Stéphanie; Cerny, Andreas; Dollenmaier, Günter; Dufour, Jean-François; Gerlach, Tilman J; Heim, Markus H; Malinverni, Raffaele; Müllhaupt, Beat; Negro, Francesco; Moradpour, Darius; Bochud, Pierre-Yves; Swiss Hepatitis C Cohort Study Group, (2012). Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy. Hepatology, 55(4), pp. 1038-47. Hoboken, N.J.: Wiley Interscience 10.1002/hep.24787
Cai, Tao; Dufour, Jean-François; Muellhaupt, Beat; Gerlach, Tilman; Heim, Markus; Moradpour, Darius; Cerny, Andreas; Malinverni, Raffaele; Kaddai, Vincent; Bochud, Murielle; Negro, Francesco; Bochud, Pierre-Yves; Swiss Hepatitis C Cohort Study Group, (2011). Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis. Journal of hepatology, 55(3), pp. 529-35. Amsterdam: Elsevier 10.1016/j.jhep.2010.12.020
Kenfak-Foguena, Alain; Schöni-Affolter, Franziska; Bürgisser, Phillippe; Witteck, Andrea; Darling, Katharine E A; Kovari, Helen; Kaiser, Laurent; Evison, John-Marc; Elzi, Luigia; Gurter-De La Fuente, Vanina; Jost, Josef; Moradpour, Darius; Abravanel, Florence; Izpopet, Jacques; Cavassini, Matthais (2011). Hepatitis E Virus seroprevalence and chronic infections in patients with HIV, Switzerland. Emerging infectious diseases, 17(6), pp. 1074-1078. Atlanta, Ga.: U.S. National Center for Infectious Diseases 10.3201/eid1706.101067
De Gottardi, Andrea; Hilleret, Marie-Noelle; Gelez, Pascale; La Mura, Vincenzo; Guillaud, Olivier; Majno, Pietro; Hadengue, Antoine; Morel, Philippe; Zarski, Jean-Pierre; Fontana, Massimiliano; Moradpour, Darius; Mentha, Gilles; Boillot, Olivier; Leroy, Vincent; Giostra, Emiliano; Dumortier, Jérôme (2010). Injection drug use before and after liver transplantation: a retrospective multicenter analysis on incidence and outcome. Clinical transplantation, 24(4), pp. 564-71. Oxford: Wiley-Blackwell 10.1111/j.1399-0012.2009.01121.x
Rauch, Andri; Kutalik, Zoltán; Descombes, Patrick; Cai, Tao; Di Iulio, Julia; Mueller, Tobias; Bochud, Murielle; Battegay, Manuel; Bernasconi, Enos; Borovicka, Jan; Colombo, Sara; Cerny, Andreas; Dufour, Jean-François; Furrer, Hansjakob; Günthard, Huldrych F; Heim, Markus; Hirschel, Bernard; Malinverni, Raffaele; Moradpour, Darius; Müllhaupt, Beat; ... (2010). Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology, 138(4), 1338-45, 1345.e1-7. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2009.12.056
Bochud, Pierre-Yves; Cai, Tao; Overbeck, Kathrin; Bochud, Murielle; Dufour, Jean-François; Müllhaupt, Beat; Borovicka, Jan; Heim, Markus; Moradpour, Darius; Cerny, Andreas; Malinverni, Raffaele; Francioli, Patrick; Negro, Francesco (2009). Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C. Journal of hepatology, 51(4), pp. 655-66. Amsterdam: Elsevier 10.1016/j.jhep.2009.05.016