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Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter Methys; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). Mice Lacking a Novel Phosphosite on MET Display ASD-Associated Behavior Pattern (Unpublished). In: Annual meeting of the Swiss Society for Neuroscience. Lugano, Switzerland. 09. – 10.06.2023.
Hayrapetyan, Liana; Degen, Peter Methys; Bouteiller, Sofiane; Riedo, Rahel; Quintin, Aurélie; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; levitt, pat; Zimmer, Yitzhak; Medova, Michaela (2023). Sex- and strain-dependent dominant behavior in mice lacking the novel S1014 phosphosite on the ASD risk gene MET. (Unpublished). In: Clinical Neuroscience Bern. Bern, Switzerland. 08.09.2023.
Poliaková Turan, Michaela; Riedo, Rahel; Medo, Matúš; Pozzato, Chiara; Friese-Hamim, Manja; Koch, Jonas Paul; Coggins, Si'Ana A; Li, Qun; Kim, Baek; Albers, Joachim; Aebersold, Daniel M; Zamboni, Nicola; Zimmer, Yitzhak; Medová, Michaela (2024). E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network. Cancer research communications, 4(7), pp. 1863-1880. American Association for Cancer Research 10.1158/2767-9764.CRC-23-0370
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Hovhannisyan, Lusine; Riether, Carsten; Aebersold, Daniel M; Medova, Michaela; Zimmer, Yitzhak (2023). CAR T cell-based immunotherapy and radiation therapy: potential, promises and risks. Molecular cancer, 22(1), p. 82. BioMed Central 10.1186/s12943-023-01775-1
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter Methys; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). Mice Lacking a Novel Phosphosite on MET Display ASD-Associated Behavior Pattern (Unpublished). In: Annual meeting of the Swiss Society for Neuroscience. Lugano, Switzerland. 09. – 10.06.2023.
Pozzato, Chiara; Koch, Jonas Paul; Riedo, Rahel; Hayrapetyan, Liana; Medo, Matúš; Aebersold, Daniel Matthias; Zimmer, Yitzhak; Medova, Michaela (2023). A newly discovered phosphorylation site of the MET receptor tyrosine kinase, Ser1016, in mediating tumour growth and cancer therapy resistance. (Unpublished). In: BCRC Retreat. Bern, Switzerland. 26.06.2023.
Hayrapetyan, Liana; Degen, Peter Methys; Bouteiller, Sofiane; Riedo, Rahel; Quintin, Aurélie; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; levitt, pat; Zimmer, Yitzhak; Medova, Michaela (2023). Sex- and strain-dependent dominant behavior in mice lacking the novel S1014 phosphosite on the ASD risk gene MET. (Unpublished). In: Clinical Neuroscience Bern. Bern, Switzerland. 08.09.2023.
Schanne, Daniel H; Koch, Alexander; Elicin, Olgun; Giger, Roland; Medová, Michaela; Zimmer, Yitzhak; Aebersold, Daniel M (2022). Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review. Biomedicines, 10(12) MDPI 10.3390/biomedicines10123288
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Medova, Michaela; Medo, Matúš; Hovhannisyan, Lusine; Muñoz-Maldonado, Carmen; Aebersold, Daniel M.; Zimmer, Yitzhak (2020). DNA-PK in human malignant disorders: Mechanisms and implications for pharmacological interventions. Pharmacology & therapeutics, 215, p. 107617. Elsevier 10.1016/j.pharmthera.2020.107617
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Koch, Jonas P.; Aebersold, Daniel M.; Zimmer, Yitzhak; Medová, Michaela (2020). MET targeting: time for a rematch. Oncogene, 39(14), pp. 2845-2862. Springer Nature 10.1038/s41388-020-1193-8
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Medo, Matúš; Aebersold, Daniel M.; Medova, Michaela (2019). ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data. BMC bioinformatics, 20(1), p. 563. BioMed Central 10.1186/s12859-019-3144-3
Poliaková, Michaela; Felser, Andrea; Pierzchala, Katarzyna; Nuoffer, Jean-Marc; Aebersold, Daniel; Zimmer, Yitzhak; Zamboni, Nicola; Medova, Michaela (2019). Metabolomics reveals tepotinib-related mitochondrial dysfunction in MET activating mutations-driven models. FEBS journal, 286(14), pp. 2692-2710. Wiley-Blackwell 10.1111/febs.14852
Orlando, Eleonora; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2019). Oncogene addiction as a foundation of targeted cancer therapy: The paradigm of the MET receptor tyrosine kinase. Cancer letters, 443, pp. 189-202. Elsevier 10.1016/j.canlet.2018.12.001
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Poliakova, Michaela; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2018). The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer. Molecular cancer, 17(1), p. 27. BioMed Central 10.1186/s12943-018-0798-9
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Melin, Nicolas; Sánchez Taltavull, Daniel; Petit, B.; Herman, E.; Zimmer, Yitzhak; Candinas, Daniel; Vozenin, M.C.; Aebersold, Daniel; Keogh-Stroka, Deborah M. (2018). SP-0330: Science slam: Report back from ESTRO mobility grants biology: Development of a radiation induced liver damage model. Radiotherapy and oncology, 127(Suppl. 1), S175-S176. Elsevier 10.1016/S0167-8140(18)30640-6
Herrmann, Evelyn; Naehrig, Diana; Sassowsky, Manfred; Bigler, Martin; Buijsen, Jeroen; Ciernik, Ilja; Zwahlen, Daniel; Pellanda, Alessandra Franzetti; Meister, Andreas; Brauchli, Peter; Berardi, Simona; Kuettel, Erika; Dufour, Jean-François; Aebersold, Daniel; Swiss Group for Clinical Cancer Research, SAKK (2017). External beam radiotherapy for unresectable hepatocellular carcinoma, an international multicenter phase I trial, SAKK 77/07 and SASL 26. Radiation oncology, 12(1), p. 12. BioMed Central 10.1186/s13014-016-0745-0
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Nisa Hernandez, Lluis; Salmina, Cinzia; Dettmer, Matthias; Arnold, Andreas; Aebersold, Daniel; Borner, Urs; Giger, Roland (2015). Implications of intraglandular lymph node metastases in primary carcinomas of the parotid gland. The Laryngoscope, 125(9), pp. 2099-2106. Wiley 10.1002/lary.25342
Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001
Leiser, Dominic; Pochon, Benoît; Blank Wieslawa, Elzbieta; Francica, Paola; Glück, Astrid; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2014). Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation. FEBS letters, 588(5), pp. 653-658. Elsevier 10.1016/j.febslet.2013.12.025
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Nita, Izabela Magdalena; Hostettler, Katrin; Tamò, Luca Giuseppe Athos; Medova, Michaela; Bombaci, Giuseppe; Zhong, Jun; Allam, Ramanjaneyulu; Zimmer, Yitzhak; Roth, Michael; Geiser, Thomas; Gazdhar, Amiq (2017). Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Scientific Reports, 7(41901), p. 41901. Nature Publishing Group 10.1038/srep41901
Nisa Hernandez, Lluis; Salmina, Cinzia; Dettmer, Matthias; Arnold, Andreas; Aebersold, Daniel; Borner, Urs; Giger, Roland (2015). Implications of intraglandular lymph node metastases in primary carcinomas of the parotid gland. The Laryngoscope, 125(9), pp. 2099-2106. Wiley 10.1002/lary.25342
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Rutaihwa, Liliana K.; Menardo, Fabrizio; Stucki, David; Gygli, Sebastian M.; Ley, Serej D.; Malla, Bijaya; Feldmann, Julia; Borrell, Sonia; Beisel, Christian; Middelkoop, Kerren; Carter, E. Jane; Diero, Lameck; Ballif, Marie; Jugheli, Levan; Reither, Klaus; Fenner, Lukas; Brites, Daniela; Gagneux, Sebastien (2019). Multiple Introductions of Mycobacterium tuberculosis Lineage 2–Beijing Into Africa Over Centuries (In Press). Frontiers in ecology and evolution, 7, p. 112. Frontiers Media 10.3389/fevo.2019.00112
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Leiser, Dominic; Pochon, Benoît; Blank Wieslawa, Elzbieta; Francica, Paola; Glück, Astrid; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2014). Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation. FEBS letters, 588(5), pp. 653-658. Elsevier 10.1016/j.febslet.2013.12.025
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Nita, Izabela Magdalena; Hostettler, Katrin; Tamò, Luca Giuseppe Athos; Medova, Michaela; Bombaci, Giuseppe; Zhong, Jun; Allam, Ramanjaneyulu; Zimmer, Yitzhak; Roth, Michael; Geiser, Thomas; Gazdhar, Amiq (2017). Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Scientific Reports, 7(41901), p. 41901. Nature Publishing Group 10.1038/srep41901
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Holtz, F; Monnier, Y; Borner, Urs; Nisa, Lluis (2017). Bilateral lingual artery stenosis: A rare, late complication of chemoradiotherapy. European annals of otorhinolaryngology, head and neck diseases, 134(4), pp. 269-271. Elsevier 10.1016/j.anorl.2017.02.002
Nisa Hernandez, Lluis; Salmina, Cinzia; Dettmer, Matthias; Arnold, Andreas; Aebersold, Daniel; Borner, Urs; Giger, Roland (2015). Implications of intraglandular lymph node metastases in primary carcinomas of the parotid gland. The Laryngoscope, 125(9), pp. 2099-2106. Wiley 10.1002/lary.25342
Poot, A. M.; Diercks, G. F. H.; Kramer, D.; Schepens, Isabelle; Klunder, G.; Hashimoto, T.; Borradori, Luca; Jonkman, M. F.; Pas, H. H. (2013). Laboratory diagnosis of paraneoplastic pemphigus. British journal of dermatology, 169(5), pp. 1016-1024. Wiley-Blackwell 10.1111/bjd.12479
Numata, Sanae; Teye, Kwesi; Tsuruta, Daisuke; Sogame, Ryosuke; Ishii, Norito; Koga, Hiroshi; Natsuaki, Yohei; Tsuchisaka, Atsunari; Hamada, Takahiro; Karashima, Tadashi; Nakama, Takekuni; Furumura, Minao; Ohata, Chika; Kawakami, Tamihiro; Schepens, Isabelle; Borradori, Luca; Hashimoto, Takashi (2013). Anti-Alpha-2-Macroglobulin-Like-1 Autoantibodies Are Detected Frequently and May Be Pathogenic in Paraneoplastic Pemphigus. Journal of Investigative Dermatology, 133(7), pp. 1785-1793. Nature Publishing 10.1038/jid.2013.65
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter Methys; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). Mice Lacking a Novel Phosphosite on MET Display ASD-Associated Behavior Pattern (Unpublished). In: Annual meeting of the Swiss Society for Neuroscience. Lugano, Switzerland. 09. – 10.06.2023.
Hayrapetyan, Liana; Degen, Peter Methys; Bouteiller, Sofiane; Riedo, Rahel; Quintin, Aurélie; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; levitt, pat; Zimmer, Yitzhak; Medova, Michaela (2023). Sex- and strain-dependent dominant behavior in mice lacking the novel S1014 phosphosite on the ASD risk gene MET. (Unpublished). In: Clinical Neuroscience Bern. Bern, Switzerland. 08.09.2023.
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Brodie, Tess; Tosevski, Vinko; Medova, Michaela (2018). OMIP-045: Characterizing human head and neck tumors and cancer cell lines with mass cytometry. Cytometry Part A, 93(4), pp. 406-410. Wiley 10.1002/cyto.a.23336
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Melin, Nicolas; Sánchez Taltavull, Daniel; Petit, B.; Herman, E.; Zimmer, Yitzhak; Candinas, Daniel; Vozenin, M.C.; Aebersold, Daniel; Keogh-Stroka, Deborah M. (2018). SP-0330: Science slam: Report back from ESTRO mobility grants biology: Development of a radiation induced liver damage model. Radiotherapy and oncology, 127(Suppl. 1), S175-S176. Elsevier 10.1016/S0167-8140(18)30640-6
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter Methys; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). Mice Lacking a Novel Phosphosite on MET Display ASD-Associated Behavior Pattern (Unpublished). In: Annual meeting of the Swiss Society for Neuroscience. Lugano, Switzerland. 09. – 10.06.2023.
Degen, Peter Methys; Medo, Matúš (2023). Replicability of bulk RNA-Seq differential expression and enrichment analysis results in cancer research. (Unpublished). In: GCB Symposium, University of Bern. Bern, Switzerland. 19.06.2023.
Degen, Peter Methys; Medo, Matúš (2023). Replicability of bulk RNA-Seq differential expression and enrichment analysis results in cancer research. (Unpublished). In: DBMR Research Day, University of Bern. Bern, Switzerland. 05.07.2023.
Hayrapetyan, Liana; Degen, Peter Methys; Bouteiller, Sofiane; Riedo, Rahel; Quintin, Aurélie; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; levitt, pat; Zimmer, Yitzhak; Medova, Michaela (2023). Sex- and strain-dependent dominant behavior in mice lacking the novel S1014 phosphosite on the ASD risk gene MET. (Unpublished). In: Clinical Neuroscience Bern. Bern, Switzerland. 08.09.2023.
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Nisa Hernandez, Lluis; Salmina, Cinzia; Dettmer, Matthias; Arnold, Andreas; Aebersold, Daniel; Borner, Urs; Giger, Roland (2015). Implications of intraglandular lymph node metastases in primary carcinomas of the parotid gland. The Laryngoscope, 125(9), pp. 2099-2106. Wiley 10.1002/lary.25342
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Herrmann, Evelyn; Naehrig, Diana; Sassowsky, Manfred; Bigler, Martin; Buijsen, Jeroen; Ciernik, Ilja; Zwahlen, Daniel; Pellanda, Alessandra Franzetti; Meister, Andreas; Brauchli, Peter; Berardi, Simona; Kuettel, Erika; Dufour, Jean-François; Aebersold, Daniel; Swiss Group for Clinical Cancer Research, SAKK (2017). External beam radiotherapy for unresectable hepatocellular carcinoma, an international multicenter phase I trial, SAKK 77/07 and SASL 26. Radiation oncology, 12(1), p. 12. BioMed Central 10.1186/s13014-016-0745-0
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Schanne, Daniel H; Koch, Alexander; Elicin, Olgun; Giger, Roland; Medová, Michaela; Zimmer, Yitzhak; Aebersold, Daniel M (2022). Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review. Biomedicines, 10(12) MDPI 10.3390/biomedicines10123288
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Poliaková, Michaela; Felser, Andrea; Pierzchala, Katarzyna; Nuoffer, Jean-Marc; Aebersold, Daniel; Zimmer, Yitzhak; Zamboni, Nicola; Medova, Michaela (2019). Metabolomics reveals tepotinib-related mitochondrial dysfunction in MET activating mutations-driven models. FEBS journal, 286(14), pp. 2692-2710. Wiley-Blackwell 10.1111/febs.14852
Rutaihwa, Liliana K.; Menardo, Fabrizio; Stucki, David; Gygli, Sebastian M.; Ley, Serej D.; Malla, Bijaya; Feldmann, Julia; Borrell, Sonia; Beisel, Christian; Middelkoop, Kerren; Carter, E. Jane; Diero, Lameck; Ballif, Marie; Jugheli, Levan; Reither, Klaus; Fenner, Lukas; Brites, Daniela; Gagneux, Sebastien (2019). Multiple Introductions of Mycobacterium tuberculosis Lineage 2–Beijing Into Africa Over Centuries (In Press). Frontiers in ecology and evolution, 7, p. 112. Frontiers Media 10.3389/fevo.2019.00112
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Leiser, Dominic; Pochon, Benoît; Blank Wieslawa, Elzbieta; Francica, Paola; Glück, Astrid; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2014). Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation. FEBS letters, 588(5), pp. 653-658. Elsevier 10.1016/j.febslet.2013.12.025
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Nita, Izabela Magdalena; Hostettler, Katrin; Tamò, Luca Giuseppe Athos; Medova, Michaela; Bombaci, Giuseppe; Zhong, Jun; Allam, Ramanjaneyulu; Zimmer, Yitzhak; Roth, Michael; Geiser, Thomas; Gazdhar, Amiq (2017). Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Scientific Reports, 7(41901), p. 41901. Nature Publishing Group 10.1038/srep41901
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Nita, Izabela Magdalena; Hostettler, Katrin; Tamò, Luca Giuseppe Athos; Medova, Michaela; Bombaci, Giuseppe; Zhong, Jun; Allam, Ramanjaneyulu; Zimmer, Yitzhak; Roth, Michael; Geiser, Thomas; Gazdhar, Amiq (2017). Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Scientific Reports, 7(41901), p. 41901. Nature Publishing Group 10.1038/srep41901
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Schanne, Daniel H; Koch, Alexander; Elicin, Olgun; Giger, Roland; Medová, Michaela; Zimmer, Yitzhak; Aebersold, Daniel M (2022). Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review. Biomedicines, 10(12) MDPI 10.3390/biomedicines10123288
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Nisa Hernandez, Lluis; Salmina, Cinzia; Dettmer, Matthias; Arnold, Andreas; Aebersold, Daniel; Borner, Urs; Giger, Roland (2015). Implications of intraglandular lymph node metastases in primary carcinomas of the parotid gland. The Laryngoscope, 125(9), pp. 2099-2106. Wiley 10.1002/lary.25342
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Leiser, Dominic; Pochon, Benoît; Blank Wieslawa, Elzbieta; Francica, Paola; Glück, Astrid; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2014). Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation. FEBS letters, 588(5), pp. 653-658. Elsevier 10.1016/j.febslet.2013.12.025
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter Methys; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). Mice Lacking a Novel Phosphosite on MET Display ASD-Associated Behavior Pattern (Unpublished). In: Annual meeting of the Swiss Society for Neuroscience. Lugano, Switzerland. 09. – 10.06.2023.
Pozzato, Chiara; Koch, Jonas Paul; Riedo, Rahel; Hayrapetyan, Liana; Medo, Matúš; Aebersold, Daniel Matthias; Zimmer, Yitzhak; Medova, Michaela (2023). A newly discovered phosphorylation site of the MET receptor tyrosine kinase, Ser1016, in mediating tumour growth and cancer therapy resistance. (Unpublished). In: BCRC Retreat. Bern, Switzerland. 26.06.2023.
Hayrapetyan, Liana; Degen, Peter Methys; Bouteiller, Sofiane; Riedo, Rahel; Quintin, Aurélie; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; levitt, pat; Zimmer, Yitzhak; Medova, Michaela (2023). Sex- and strain-dependent dominant behavior in mice lacking the novel S1014 phosphosite on the ASD risk gene MET. (Unpublished). In: Clinical Neuroscience Bern. Bern, Switzerland. 08.09.2023.
Herrmann, Evelyn; Naehrig, Diana; Sassowsky, Manfred; Bigler, Martin; Buijsen, Jeroen; Ciernik, Ilja; Zwahlen, Daniel; Pellanda, Alessandra Franzetti; Meister, Andreas; Brauchli, Peter; Berardi, Simona; Kuettel, Erika; Dufour, Jean-François; Aebersold, Daniel; Swiss Group for Clinical Cancer Research, SAKK (2017). External beam radiotherapy for unresectable hepatocellular carcinoma, an international multicenter phase I trial, SAKK 77/07 and SASL 26. Radiation oncology, 12(1), p. 12. BioMed Central 10.1186/s13014-016-0745-0
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Hovhannisyan, Lusine; Riether, Carsten; Aebersold, Daniel M; Medova, Michaela; Zimmer, Yitzhak (2023). CAR T cell-based immunotherapy and radiation therapy: potential, promises and risks. Molecular cancer, 22(1), p. 82. BioMed Central 10.1186/s12943-023-01775-1
Medova, Michaela; Medo, Matúš; Hovhannisyan, Lusine; Muñoz-Maldonado, Carmen; Aebersold, Daniel M.; Zimmer, Yitzhak (2020). DNA-PK in human malignant disorders: Mechanisms and implications for pharmacological interventions. Pharmacology & therapeutics, 215, p. 107617. Elsevier 10.1016/j.pharmthera.2020.107617
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Vermathen, Martina; von Tengg-Kobligk, Hendrik; Hungerbühler, Martin Nils; Vermathen, Peter; Ruprecht, Nico (2021). 1H HR-MAS NMR Based Metabolic Profiling of Lung Cancer Cells with Induced and De-Induced Cisplatin Resistance to Reveal Metabolic Resistance Adaptations. Molecules, 26(22), p. 6766. MDPI 10.3390/molecules26226766
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Melin, Nicolas; Sánchez Taltavull, Daniel; Petit, B.; Herman, E.; Zimmer, Yitzhak; Candinas, Daniel; Vozenin, M.C.; Aebersold, Daniel; Keogh-Stroka, Deborah M. (2018). SP-0330: Science slam: Report back from ESTRO mobility grants biology: Development of a radiation induced liver damage model. Radiotherapy and oncology, 127(Suppl. 1), S175-S176. Elsevier 10.1016/S0167-8140(18)30640-6
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Schanne, Daniel H; Koch, Alexander; Elicin, Olgun; Giger, Roland; Medová, Michaela; Zimmer, Yitzhak; Aebersold, Daniel M (2022). Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review. Biomedicines, 10(12) MDPI 10.3390/biomedicines10123288
Poliaková Turan, Michaela; Riedo, Rahel; Medo, Matúš; Pozzato, Chiara; Friese-Hamim, Manja; Koch, Jonas Paul; Coggins, Si'Ana A; Li, Qun; Kim, Baek; Albers, Joachim; Aebersold, Daniel M; Zamboni, Nicola; Zimmer, Yitzhak; Medová, Michaela (2024). E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network. Cancer research communications, 4(7), pp. 1863-1880. American Association for Cancer Research 10.1158/2767-9764.CRC-23-0370
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Pozzato, Chiara; Koch, Jonas Paul; Riedo, Rahel; Hayrapetyan, Liana; Medo, Matúš; Aebersold, Daniel Matthias; Zimmer, Yitzhak; Medova, Michaela (2023). A newly discovered phosphorylation site of the MET receptor tyrosine kinase, Ser1016, in mediating tumour growth and cancer therapy resistance. (Unpublished). In: BCRC Retreat. Bern, Switzerland. 26.06.2023.
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Koch, Jonas P.; Aebersold, Daniel M.; Zimmer, Yitzhak; Medová, Michaela (2020). MET targeting: time for a rematch. Oncogene, 39(14), pp. 2845-2862. Springer Nature 10.1038/s41388-020-1193-8
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001
Leiser, Dominic; Pochon, Benoît; Blank Wieslawa, Elzbieta; Francica, Paola; Glück, Astrid; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2014). Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation. FEBS letters, 588(5), pp. 653-658. Elsevier 10.1016/j.febslet.2013.12.025
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Rutaihwa, Liliana K.; Menardo, Fabrizio; Stucki, David; Gygli, Sebastian M.; Ley, Serej D.; Malla, Bijaya; Feldmann, Julia; Borrell, Sonia; Beisel, Christian; Middelkoop, Kerren; Carter, E. Jane; Diero, Lameck; Ballif, Marie; Jugheli, Levan; Reither, Klaus; Fenner, Lukas; Brites, Daniela; Gagneux, Sebastien (2019). Multiple Introductions of Mycobacterium tuberculosis Lineage 2–Beijing Into Africa Over Centuries (In Press). Frontiers in ecology and evolution, 7, p. 112. Frontiers Media 10.3389/fevo.2019.00112
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Poliaková Turan, Michaela; Riedo, Rahel; Medo, Matúš; Pozzato, Chiara; Friese-Hamim, Manja; Koch, Jonas Paul; Coggins, Si'Ana A; Li, Qun; Kim, Baek; Albers, Joachim; Aebersold, Daniel M; Zamboni, Nicola; Zimmer, Yitzhak; Medová, Michaela (2024). E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network. Cancer research communications, 4(7), pp. 1863-1880. American Association for Cancer Research 10.1158/2767-9764.CRC-23-0370
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter Methys; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). Mice Lacking a Novel Phosphosite on MET Display ASD-Associated Behavior Pattern (Unpublished). In: Annual meeting of the Swiss Society for Neuroscience. Lugano, Switzerland. 09. – 10.06.2023.
Degen, Peter Methys; Medo, Matúš (2023). Replicability of bulk RNA-Seq differential expression and enrichment analysis results in cancer research. (Unpublished). In: GCB Symposium, University of Bern. Bern, Switzerland. 19.06.2023.
Pozzato, Chiara; Koch, Jonas Paul; Riedo, Rahel; Hayrapetyan, Liana; Medo, Matúš; Aebersold, Daniel Matthias; Zimmer, Yitzhak; Medova, Michaela (2023). A newly discovered phosphorylation site of the MET receptor tyrosine kinase, Ser1016, in mediating tumour growth and cancer therapy resistance. (Unpublished). In: BCRC Retreat. Bern, Switzerland. 26.06.2023.
Degen, Peter Methys; Medo, Matúš (2023). Replicability of bulk RNA-Seq differential expression and enrichment analysis results in cancer research. (Unpublished). In: DBMR Research Day, University of Bern. Bern, Switzerland. 05.07.2023.
Hayrapetyan, Liana; Degen, Peter Methys; Bouteiller, Sofiane; Riedo, Rahel; Quintin, Aurélie; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; levitt, pat; Zimmer, Yitzhak; Medova, Michaela (2023). Sex- and strain-dependent dominant behavior in mice lacking the novel S1014 phosphosite on the ASD risk gene MET. (Unpublished). In: Clinical Neuroscience Bern. Bern, Switzerland. 08.09.2023.
Medo, Matúš (2023). Comprehensive evaluation of tools for fitting mutational signatures. (Unpublished). In: Basel Computational Biology Conference. Basel, Switzerland. 11.-13.09.2023.
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Medova, Michaela; Medo, Matúš; Hovhannisyan, Lusine; Muñoz-Maldonado, Carmen; Aebersold, Daniel M.; Zimmer, Yitzhak (2020). DNA-PK in human malignant disorders: Mechanisms and implications for pharmacological interventions. Pharmacology & therapeutics, 215, p. 107617. Elsevier 10.1016/j.pharmthera.2020.107617
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Xu, Shuqi; Mariani, Manuel Sebastian; Lü, Linyuan; Medo, Matúš (2020). Unbiased evaluation of ranking metrics reveals consistent performance in science and technology citation data. Journal of informetrics, 14(1), p. 101005. Elsevier 10.1016/j.joi.2019.101005
Medo, Matúš; Aebersold, Daniel M.; Medova, Michaela (2019). ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data. BMC bioinformatics, 20(1), p. 563. BioMed Central 10.1186/s12859-019-3144-3
Mariani, Manuel Sebastian; Medo, Matúš; Lafond, François (2019). Early identification of important patents: Design and validation of citation network metrics. Technological forecasting and social change, 146, pp. 644-654. Elsevier 10.1016/j.techfore.2018.01.036
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Ren, Zhuo-Ming; Mariani, Manuel Sebastian; Zhang, Yi-Cheng; Medo, Matúš (2018). Randomizing growing networks with a time-respecting null model. Physical review. E - statistical, nonlinear, and soft matter physics, 97(5-1), 052311. American Physical Society 10.1103/PhysRevE.97.052311
Liao, Hao; Mariani, Manuel Sebastian; Medo, Matúš; Zhang, Yi-Cheng; Zhou, Ming-Yang (2017). Ranking in evolving complex networks. Physics reports - review section of the Physics letters, 689, pp. 1-54. Elsevier Science 10.1016/j.physrep.2017.05.001
Vaccario, Giacomo; Medo, Matúš; Wider, Nicolas; Mariani, Manuel Sebastian (2017). Quantifying and suppressing ranking bias in a large citation network. Journal of informetrics, 11(3), pp. 766-782. Elsevier 10.1016/j.joi.2017.05.014
Poliaková Turan, Michaela; Riedo, Rahel; Medo, Matúš; Pozzato, Chiara; Friese-Hamim, Manja; Koch, Jonas Paul; Coggins, Si'Ana A; Li, Qun; Kim, Baek; Albers, Joachim; Aebersold, Daniel M; Zamboni, Nicola; Zimmer, Yitzhak; Medová, Michaela (2024). E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network. Cancer research communications, 4(7), pp. 1863-1880. American Association for Cancer Research 10.1158/2767-9764.CRC-23-0370
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Hovhannisyan, Lusine; Riether, Carsten; Aebersold, Daniel M; Medova, Michaela; Zimmer, Yitzhak (2023). CAR T cell-based immunotherapy and radiation therapy: potential, promises and risks. Molecular cancer, 22(1), p. 82. BioMed Central 10.1186/s12943-023-01775-1
Dennstädt, Fabio; Glatzer, Markus; Medová, Michaela; Putora, Paul Martin (2023). In Reply to Raaijmakers et al. International journal of radiation oncology, biology, physics, 115(4), p. 1005. Elsevier 10.1016/j.ijrobp.2022.11.019
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Dennstädt, Fabio; Medova, Michaela; Putora, Paul Martin; Glatzer, Markus (2023). Parameters of the Lyman model for calculation of normal tissue complication probability: a systematic literature review. International journal of radiation oncology, biology, physics, 115(3), pp. 696-706. Elsevier 10.1016/j.ijrobp.2022.08.039
Zabini, Adam; Zimmer, Yitzhak; Medová, Michaela (2023). Beyond keratinocyte differentiation: emerging new biology of small proline-rich proteins. Trends in cell biology, 33(1), pp. 5-8. Elsevier 10.1016/j.tcb.2022.08.002
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter Methys; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). Mice Lacking a Novel Phosphosite on MET Display ASD-Associated Behavior Pattern (Unpublished). In: Annual meeting of the Swiss Society for Neuroscience. Lugano, Switzerland. 09. – 10.06.2023.
Pozzato, Chiara; Koch, Jonas Paul; Riedo, Rahel; Hayrapetyan, Liana; Medo, Matúš; Aebersold, Daniel Matthias; Zimmer, Yitzhak; Medova, Michaela (2023). A newly discovered phosphorylation site of the MET receptor tyrosine kinase, Ser1016, in mediating tumour growth and cancer therapy resistance. (Unpublished). In: BCRC Retreat. Bern, Switzerland. 26.06.2023.
Hayrapetyan, Liana; Degen, Peter Methys; Bouteiller, Sofiane; Riedo, Rahel; Quintin, Aurélie; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; levitt, pat; Zimmer, Yitzhak; Medova, Michaela (2023). Sex- and strain-dependent dominant behavior in mice lacking the novel S1014 phosphosite on the ASD risk gene MET. (Unpublished). In: Clinical Neuroscience Bern. Bern, Switzerland. 08.09.2023.
Schanne, Daniel H; Koch, Alexander; Elicin, Olgun; Giger, Roland; Medová, Michaela; Zimmer, Yitzhak; Aebersold, Daniel M (2022). Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review. Biomedicines, 10(12) MDPI 10.3390/biomedicines10123288
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Medova, Michaela; Medo, Matúš; Hovhannisyan, Lusine; Muñoz-Maldonado, Carmen; Aebersold, Daniel M.; Zimmer, Yitzhak (2020). DNA-PK in human malignant disorders: Mechanisms and implications for pharmacological interventions. Pharmacology & therapeutics, 215, p. 107617. Elsevier 10.1016/j.pharmthera.2020.107617
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Koch, Jonas P.; Aebersold, Daniel M.; Zimmer, Yitzhak; Medová, Michaela (2020). MET targeting: time for a rematch. Oncogene, 39(14), pp. 2845-2862. Springer Nature 10.1038/s41388-020-1193-8
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Zimmer, Yitzhak; Reinhardt, Hans Christian; Medová, Michaela (2020). Editorial: Exploiting DNA Damage Response in the Era of Precision Oncology. Frontiers in oncology, 10, p. 611127. Frontiers Research Foundation 10.3389/fonc.2020.611127
Medo, Matúš; Aebersold, Daniel M.; Medova, Michaela (2019). ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data. BMC bioinformatics, 20(1), p. 563. BioMed Central 10.1186/s12859-019-3144-3
Poliaková, Michaela; Felser, Andrea; Pierzchala, Katarzyna; Nuoffer, Jean-Marc; Aebersold, Daniel; Zimmer, Yitzhak; Zamboni, Nicola; Medova, Michaela (2019). Metabolomics reveals tepotinib-related mitochondrial dysfunction in MET activating mutations-driven models. FEBS journal, 286(14), pp. 2692-2710. Wiley-Blackwell 10.1111/febs.14852
Orlando, Eleonora; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2019). Oncogene addiction as a foundation of targeted cancer therapy: The paradigm of the MET receptor tyrosine kinase. Cancer letters, 443, pp. 189-202. Elsevier 10.1016/j.canlet.2018.12.001
Muñoz-Maldonado, Carmen; Zimmer, Yitzhak; Medova, Michaela (2019). A Comparative Analysis of Individual RAS Mutations in Cancer Biology. Frontiers in oncology, 9, p. 1088. Frontiers Research Foundation 10.3389/fonc.2019.01088
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Brodie, Tess; Tosevski, Vinko; Medova, Michaela (2018). OMIP-045: Characterizing human head and neck tumors and cancer cell lines with mass cytometry. Cytometry Part A, 93(4), pp. 406-410. Wiley 10.1002/cyto.a.23336
Poliakova, Michaela; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2018). The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer. Molecular cancer, 17(1), p. 27. BioMed Central 10.1186/s12943-018-0798-9
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Nita, Izabela Magdalena; Hostettler, Katrin; Tamò, Luca Giuseppe Athos; Medova, Michaela; Bombaci, Giuseppe; Zhong, Jun; Allam, Ramanjaneyulu; Zimmer, Yitzhak; Roth, Michael; Geiser, Thomas; Gazdhar, Amiq (2017). Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Scientific Reports, 7(41901), p. 41901. Nature Publishing Group 10.1038/srep41901
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001
Leiser, Dominic; Pochon, Benoît; Blank Wieslawa, Elzbieta; Francica, Paola; Glück, Astrid; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2014). Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation. FEBS letters, 588(5), pp. 653-658. Elsevier 10.1016/j.febslet.2013.12.025
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Melin, Nicolas; Sánchez Taltavull, Daniel; Petit, B.; Herman, E.; Zimmer, Yitzhak; Candinas, Daniel; Vozenin, M.C.; Aebersold, Daniel; Keogh-Stroka, Deborah M. (2018). SP-0330: Science slam: Report back from ESTRO mobility grants biology: Development of a radiation induced liver damage model. Radiotherapy and oncology, 127(Suppl. 1), S175-S176. Elsevier 10.1016/S0167-8140(18)30640-6
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Medova, Michaela; Medo, Matúš; Hovhannisyan, Lusine; Muñoz-Maldonado, Carmen; Aebersold, Daniel M.; Zimmer, Yitzhak (2020). DNA-PK in human malignant disorders: Mechanisms and implications for pharmacological interventions. Pharmacology & therapeutics, 215, p. 107617. Elsevier 10.1016/j.pharmthera.2020.107617
Muñoz-Maldonado, Carmen; Zimmer, Yitzhak; Medova, Michaela (2019). A Comparative Analysis of Individual RAS Mutations in Cancer Biology. Frontiers in oncology, 9, p. 1088. Frontiers Research Foundation 10.3389/fonc.2019.01088
Holtz, F; Monnier, Y; Borner, Urs; Nisa, Lluis (2017). Bilateral lingual artery stenosis: A rare, late complication of chemoradiotherapy. European annals of otorhinolaryngology, head and neck diseases, 134(4), pp. 269-271. Elsevier 10.1016/j.anorl.2017.02.002
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Nisa Hernandez, Lluis; Salmina, Cinzia; Dettmer, Matthias; Arnold, Andreas; Aebersold, Daniel; Borner, Urs; Giger, Roland (2015). Implications of intraglandular lymph node metastases in primary carcinomas of the parotid gland. The Laryngoscope, 125(9), pp. 2099-2106. Wiley 10.1002/lary.25342
Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001
Nita, Izabela Magdalena; Hostettler, Katrin; Tamò, Luca Giuseppe Athos; Medova, Michaela; Bombaci, Giuseppe; Zhong, Jun; Allam, Ramanjaneyulu; Zimmer, Yitzhak; Roth, Michael; Geiser, Thomas; Gazdhar, Amiq (2017). Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Scientific Reports, 7(41901), p. 41901. Nature Publishing Group 10.1038/srep41901
Poliaková, Michaela; Felser, Andrea; Pierzchala, Katarzyna; Nuoffer, Jean-Marc; Aebersold, Daniel; Zimmer, Yitzhak; Zamboni, Nicola; Medova, Michaela (2019). Metabolomics reveals tepotinib-related mitochondrial dysfunction in MET activating mutations-driven models. FEBS journal, 286(14), pp. 2692-2710. Wiley-Blackwell 10.1111/febs.14852
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Orlando, Eleonora; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2019). Oncogene addiction as a foundation of targeted cancer therapy: The paradigm of the MET receptor tyrosine kinase. Cancer letters, 443, pp. 189-202. Elsevier 10.1016/j.canlet.2018.12.001
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Leiser, Dominic; Pochon, Benoît; Blank Wieslawa, Elzbieta; Francica, Paola; Glück, Astrid; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2014). Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation. FEBS letters, 588(5), pp. 653-658. Elsevier 10.1016/j.febslet.2013.12.025
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Poliaková Turan, Michaela; Riedo, Rahel; Medo, Matúš; Pozzato, Chiara; Friese-Hamim, Manja; Koch, Jonas Paul; Coggins, Si'Ana A; Li, Qun; Kim, Baek; Albers, Joachim; Aebersold, Daniel M; Zamboni, Nicola; Zimmer, Yitzhak; Medová, Michaela (2024). E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network. Cancer research communications, 4(7), pp. 1863-1880. American Association for Cancer Research 10.1158/2767-9764.CRC-23-0370
Poliaková, Michaela; Felser, Andrea; Pierzchala, Katarzyna; Nuoffer, Jean-Marc; Aebersold, Daniel; Zimmer, Yitzhak; Zamboni, Nicola; Medova, Michaela (2019). Metabolomics reveals tepotinib-related mitochondrial dysfunction in MET activating mutations-driven models. FEBS journal, 286(14), pp. 2692-2710. Wiley-Blackwell 10.1111/febs.14852
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Poliakova, Michaela; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2018). The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer. Molecular cancer, 17(1), p. 27. BioMed Central 10.1186/s12943-018-0798-9
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Poliaková Turan, Michaela; Riedo, Rahel; Medo, Matúš; Pozzato, Chiara; Friese-Hamim, Manja; Koch, Jonas Paul; Coggins, Si'Ana A; Li, Qun; Kim, Baek; Albers, Joachim; Aebersold, Daniel M; Zamboni, Nicola; Zimmer, Yitzhak; Medová, Michaela (2024). E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network. Cancer research communications, 4(7), pp. 1863-1880. American Association for Cancer Research 10.1158/2767-9764.CRC-23-0370
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Pozzato, Chiara; Koch, Jonas Paul; Riedo, Rahel; Hayrapetyan, Liana; Medo, Matúš; Aebersold, Daniel Matthias; Zimmer, Yitzhak; Medova, Michaela (2023). A newly discovered phosphorylation site of the MET receptor tyrosine kinase, Ser1016, in mediating tumour growth and cancer therapy resistance. (Unpublished). In: BCRC Retreat. Bern, Switzerland. 26.06.2023.
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Dennstädt, Fabio; Glatzer, Markus; Medová, Michaela; Putora, Paul Martin (2023). In Reply to Raaijmakers et al. International journal of radiation oncology, biology, physics, 115(4), p. 1005. Elsevier 10.1016/j.ijrobp.2022.11.019
Dennstädt, Fabio; Medova, Michaela; Putora, Paul Martin; Glatzer, Markus (2023). Parameters of the Lyman model for calculation of normal tissue complication probability: a systematic literature review. International journal of radiation oncology, biology, physics, 115(3), pp. 696-706. Elsevier 10.1016/j.ijrobp.2022.08.039
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Poliaková Turan, Michaela; Riedo, Rahel; Medo, Matúš; Pozzato, Chiara; Friese-Hamim, Manja; Koch, Jonas Paul; Coggins, Si'Ana A; Li, Qun; Kim, Baek; Albers, Joachim; Aebersold, Daniel M; Zamboni, Nicola; Zimmer, Yitzhak; Medová, Michaela (2024). E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network. Cancer research communications, 4(7), pp. 1863-1880. American Association for Cancer Research 10.1158/2767-9764.CRC-23-0370
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Hovhannisyan, Lusine; Riether, Carsten; Aebersold, Daniel M; Medova, Michaela; Zimmer, Yitzhak (2023). CAR T cell-based immunotherapy and radiation therapy: potential, promises and risks. Molecular cancer, 22(1), p. 82. BioMed Central 10.1186/s12943-023-01775-1
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Vermathen, Martina; von Tengg-Kobligk, Hendrik; Hungerbühler, Martin Nils; Vermathen, Peter; Ruprecht, Nico (2021). 1H HR-MAS NMR Based Metabolic Profiling of Lung Cancer Cells with Induced and De-Induced Cisplatin Resistance to Reveal Metabolic Resistance Adaptations. Molecules, 26(22), p. 6766. MDPI 10.3390/molecules26226766
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Nisa Hernandez, Lluis; Salmina, Cinzia; Dettmer, Matthias; Arnold, Andreas; Aebersold, Daniel; Borner, Urs; Giger, Roland (2015). Implications of intraglandular lymph node metastases in primary carcinomas of the parotid gland. The Laryngoscope, 125(9), pp. 2099-2106. Wiley 10.1002/lary.25342
Herrmann, Evelyn; Naehrig, Diana; Sassowsky, Manfred; Bigler, Martin; Buijsen, Jeroen; Ciernik, Ilja; Zwahlen, Daniel; Pellanda, Alessandra Franzetti; Meister, Andreas; Brauchli, Peter; Berardi, Simona; Kuettel, Erika; Dufour, Jean-François; Aebersold, Daniel; Swiss Group for Clinical Cancer Research, SAKK (2017). External beam radiotherapy for unresectable hepatocellular carcinoma, an international multicenter phase I trial, SAKK 77/07 and SASL 26. Radiation oncology, 12(1), p. 12. BioMed Central 10.1186/s13014-016-0745-0
Schanne, Daniel H; Koch, Alexander; Elicin, Olgun; Giger, Roland; Medová, Michaela; Zimmer, Yitzhak; Aebersold, Daniel M (2022). Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review. Biomedicines, 10(12) MDPI 10.3390/biomedicines10123288
Poot, A. M.; Diercks, G. F. H.; Kramer, D.; Schepens, Isabelle; Klunder, G.; Hashimoto, T.; Borradori, Luca; Jonkman, M. F.; Pas, H. H. (2013). Laboratory diagnosis of paraneoplastic pemphigus. British journal of dermatology, 169(5), pp. 1016-1024. Wiley-Blackwell 10.1111/bjd.12479
Numata, Sanae; Teye, Kwesi; Tsuruta, Daisuke; Sogame, Ryosuke; Ishii, Norito; Koga, Hiroshi; Natsuaki, Yohei; Tsuchisaka, Atsunari; Hamada, Takahiro; Karashima, Tadashi; Nakama, Takekuni; Furumura, Minao; Ohata, Chika; Kawakami, Tamihiro; Schepens, Isabelle; Borradori, Luca; Hashimoto, Takashi (2013). Anti-Alpha-2-Macroglobulin-Like-1 Autoantibodies Are Detected Frequently and May Be Pathogenic in Paraneoplastic Pemphigus. Journal of Investigative Dermatology, 133(7), pp. 1785-1793. Nature Publishing 10.1038/jid.2013.65
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Melin, Nicolas; Sánchez Taltavull, Daniel; Petit, B.; Herman, E.; Zimmer, Yitzhak; Candinas, Daniel; Vozenin, M.C.; Aebersold, Daniel; Keogh-Stroka, Deborah M. (2018). SP-0330: Science slam: Report back from ESTRO mobility grants biology: Development of a radiation induced liver damage model. Radiotherapy and oncology, 127(Suppl. 1), S175-S176. Elsevier 10.1016/S0167-8140(18)30640-6
Nita, Izabela Magdalena; Hostettler, Katrin; Tamò, Luca Giuseppe Athos; Medova, Michaela; Bombaci, Giuseppe; Zhong, Jun; Allam, Ramanjaneyulu; Zimmer, Yitzhak; Roth, Michael; Geiser, Thomas; Gazdhar, Amiq (2017). Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Scientific Reports, 7(41901), p. 41901. Nature Publishing Group 10.1038/srep41901
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Vermathen, Martina; von Tengg-Kobligk, Hendrik; Hungerbühler, Martin Nils; Vermathen, Peter; Ruprecht, Nico (2021). 1H HR-MAS NMR Based Metabolic Profiling of Lung Cancer Cells with Induced and De-Induced Cisplatin Resistance to Reveal Metabolic Resistance Adaptations. Molecules, 26(22), p. 6766. MDPI 10.3390/molecules26226766
Vermathen, Martina; von Tengg-Kobligk, Hendrik; Hungerbühler, Martin Nils; Vermathen, Peter; Ruprecht, Nico (2021). 1H HR-MAS NMR Based Metabolic Profiling of Lung Cancer Cells with Induced and De-Induced Cisplatin Resistance to Reveal Metabolic Resistance Adaptations. Molecules, 26(22), p. 6766. MDPI 10.3390/molecules26226766
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Riggenbach, Elena; Zabini, Adam; Kollár, Attila; Klenke, Frank M.; Kurze, Christophe; Olariu, Radu; Lese, Ioana; Stutz, Emanuel; Lössl, Kristina; Ionescu, Codruta (May 2024). Recurrence patterns after multimodal treatment including IORT for extremity soft tissue sarcomas. Journal of the European SocieTy for Radiotherapy and Oncology, 194(1), S197-S198. Elsevier
Zabini, Adam; Zimmer, Yitzhak; Medová, Michaela (2023). Beyond keratinocyte differentiation: emerging new biology of small proline-rich proteins. Trends in cell biology, 33(1), pp. 5-8. Elsevier 10.1016/j.tcb.2022.08.002
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Poliaková Turan, Michaela; Riedo, Rahel; Medo, Matúš; Pozzato, Chiara; Friese-Hamim, Manja; Koch, Jonas Paul; Coggins, Si'Ana A; Li, Qun; Kim, Baek; Albers, Joachim; Aebersold, Daniel M; Zamboni, Nicola; Zimmer, Yitzhak; Medová, Michaela (2024). E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network. Cancer research communications, 4(7), pp. 1863-1880. American Association for Cancer Research 10.1158/2767-9764.CRC-23-0370
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter; Aebersold, Daniel; Medo, Matúš; Adamantidis, Antoine; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). MICE LACKING A NOVEL PHOSPHOSITE S1014 ON THE MET RECEPTOR TYROSINE KINASE DISPLAY ASD-ASSOCIATED BEHAVIORAL PATTERN. IBRO neuroscience reports, 15(S1), S99-S99. Elsevier 10.1016/j.ibneur.2023.08.079
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Hovhannisyan, Lusine; Riether, Carsten; Aebersold, Daniel M; Medova, Michaela; Zimmer, Yitzhak (2023). CAR T cell-based immunotherapy and radiation therapy: potential, promises and risks. Molecular cancer, 22(1), p. 82. BioMed Central 10.1186/s12943-023-01775-1
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Zabini, Adam; Zimmer, Yitzhak; Medová, Michaela (2023). Beyond keratinocyte differentiation: emerging new biology of small proline-rich proteins. Trends in cell biology, 33(1), pp. 5-8. Elsevier 10.1016/j.tcb.2022.08.002
Hayrapetyan, Liana; Bouteiller, Sofiane; Quintin, Aurélie; Riedo, Rahel; Degen, Peter Methys; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; Levitt, Pat; Zimmer, Yitzhak; Medova, Michaela (2023). Mice Lacking a Novel Phosphosite on MET Display ASD-Associated Behavior Pattern (Unpublished). In: Annual meeting of the Swiss Society for Neuroscience. Lugano, Switzerland. 09. – 10.06.2023.
Pozzato, Chiara; Koch, Jonas Paul; Riedo, Rahel; Hayrapetyan, Liana; Medo, Matúš; Aebersold, Daniel Matthias; Zimmer, Yitzhak; Medova, Michaela (2023). A newly discovered phosphorylation site of the MET receptor tyrosine kinase, Ser1016, in mediating tumour growth and cancer therapy resistance. (Unpublished). In: BCRC Retreat. Bern, Switzerland. 26.06.2023.
Hayrapetyan, Liana; Degen, Peter Methys; Bouteiller, Sofiane; Riedo, Rahel; Quintin, Aurélie; Aebersold, Daniel Matthias; Medo, Matúš; Adamantidis, Antoine Roger; levitt, pat; Zimmer, Yitzhak; Medova, Michaela (2023). Sex- and strain-dependent dominant behavior in mice lacking the novel S1014 phosphosite on the ASD risk gene MET. (Unpublished). In: Clinical Neuroscience Bern. Bern, Switzerland. 08.09.2023.
Schanne, Daniel H; Koch, Alexander; Elicin, Olgun; Giger, Roland; Medová, Michaela; Zimmer, Yitzhak; Aebersold, Daniel M (2022). Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review. Biomedicines, 10(12) MDPI 10.3390/biomedicines10123288
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Bosch-Guiteras, Núria; Uroda, Tina; Guillen-Ramirez, Hugo A.; Riedo, Rahel; Gazdhar, Amiq; Esposito, Roberta; Pulido-Quetglas, Carlos; Zimmer, Yitzhak; Medová, Michaela; Johnson, Rory (2021). Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs. Genome research, 31(3), pp. 461-471. Cold Spring Harbor, N.Y 10.1101/gr.265736.120
Medova, Michaela; Medo, Matúš; Hovhannisyan, Lusine; Muñoz-Maldonado, Carmen; Aebersold, Daniel M.; Zimmer, Yitzhak (2020). DNA-PK in human malignant disorders: Mechanisms and implications for pharmacological interventions. Pharmacology & therapeutics, 215, p. 107617. Elsevier 10.1016/j.pharmthera.2020.107617
Bensimon, Ariel; Koch, Jonas P.; Francica, Paola; Roth, Selina M.; Riedo, Rahel; Glück, Astrid A.; Orlando, Eleonora; Blaukat, Andree; Aebersold, Daniel M.; Zimmer, Yitzhak; Aebersold, Ruedi; Medová, Michaela (2020). Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics. Molecular oncology, 14(6), pp. 1185-1206. Elsevier 10.1002/1878-0261.12696
Koch, Jonas P.; Aebersold, Daniel M.; Zimmer, Yitzhak; Medová, Michaela (2020). MET targeting: time for a rematch. Oncogene, 39(14), pp. 2845-2862. Springer Nature 10.1038/s41388-020-1193-8
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Zimmer, Yitzhak; Reinhardt, Hans Christian; Medová, Michaela (2020). Editorial: Exploiting DNA Damage Response in the Era of Precision Oncology. Frontiers in oncology, 10, p. 611127. Frontiers Research Foundation 10.3389/fonc.2020.611127
Poliaková, Michaela; Felser, Andrea; Pierzchala, Katarzyna; Nuoffer, Jean-Marc; Aebersold, Daniel; Zimmer, Yitzhak; Zamboni, Nicola; Medova, Michaela (2019). Metabolomics reveals tepotinib-related mitochondrial dysfunction in MET activating mutations-driven models. FEBS journal, 286(14), pp. 2692-2710. Wiley-Blackwell 10.1111/febs.14852
Orlando, Eleonora; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2019). Oncogene addiction as a foundation of targeted cancer therapy: The paradigm of the MET receptor tyrosine kinase. Cancer letters, 443, pp. 189-202. Elsevier 10.1016/j.canlet.2018.12.001
Muñoz-Maldonado, Carmen; Zimmer, Yitzhak; Medova, Michaela (2019). A Comparative Analysis of Individual RAS Mutations in Cancer Biology. Frontiers in oncology, 9, p. 1088. Frontiers Research Foundation 10.3389/fonc.2019.01088
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Poliakova, Michaela; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2018). The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer. Molecular cancer, 17(1), p. 27. BioMed Central 10.1186/s12943-018-0798-9
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Melin, Nicolas; Sánchez Taltavull, Daniel; Petit, B.; Herman, E.; Zimmer, Yitzhak; Candinas, Daniel; Vozenin, M.C.; Aebersold, Daniel; Keogh-Stroka, Deborah M. (2018). SP-0330: Science slam: Report back from ESTRO mobility grants biology: Development of a radiation induced liver damage model. Radiotherapy and oncology, 127(Suppl. 1), S175-S176. Elsevier 10.1016/S0167-8140(18)30640-6
Nita, Izabela Magdalena; Hostettler, Katrin; Tamò, Luca Giuseppe Athos; Medova, Michaela; Bombaci, Giuseppe; Zhong, Jun; Allam, Ramanjaneyulu; Zimmer, Yitzhak; Roth, Michael; Geiser, Thomas; Gazdhar, Amiq (2017). Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Scientific Reports, 7(41901), p. 41901. Nature Publishing Group 10.1038/srep41901
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001
Leiser, Dominic; Pochon, Benoît; Blank Wieslawa, Elzbieta; Francica, Paola; Glück, Astrid; Aebersold, Daniel; Zimmer, Yitzhak; Medova, Michaela (2014). Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation. FEBS letters, 588(5), pp. 653-658. Elsevier 10.1016/j.febslet.2013.12.025
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Vermathen, Martina; von Tengg-Kobligk, Hendrik; Hungerbühler, Martin Nils; Vermathen, Peter; Ruprecht, Nico (2021). 1H HR-MAS NMR Based Metabolic Profiling of Lung Cancer Cells with Induced and De-Induced Cisplatin Resistance to Reveal Metabolic Resistance Adaptations. Molecules, 26(22), p. 6766. MDPI 10.3390/molecules26226766
