0000-0003-1769-2501

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Safari, Fatemeh; Yeoh, Jeremy; Siegrist, Mark; Dolder, Silvia; Strunz, Franziska; Hofstetter, Willy; Krebs, Philippe (May 2022). Inositol Phosphatase SHIP1 – a Regulator of Osteoclast Lineage Cell Development and Activity. Bone reports, 16, p. 101404. Elsevier 10.1016/j.bonr.2022.101404

Strunz, Franziska; Siegrist, Mark; Saulacic, Nikola; Bohner, Marc; Hofstetter, Willy (May 2022). Repair of a critical-size defect in estrogen-deficient mice treated with bisphosphonates. Bone reports, 16, p. 101323. Elsevier 10.1016/j.bonr.2022.101323

Safari, Fatemeh; Yeoh, Jeremy; Bringardner, Margaux; Siegrist, Mark; Dolder, Silvia; Strunz, Franziska; Hofstetter, Willy; Krebs, Philippe (April 2021). The inositol phosphatase SHIP1 regulates skeletal development. Bone reports, 14, p. 100795. Elsevier 10.1016/j.bonr.2021.100795

Strunz, Franziska; Siegrist, Mark; Saulacic, Nikola; Bohner, Marc; Hofstetter, Willy (April 2021). Repair of a critical size defect in osteoporotic mice. Bone reports, 14, p. 100834. Elsevier 10.1016/j.bonr.2021.100834

Safari, Fatemeh; Siegrist, Mark; Dolder, Silvia; Hartmann, Eliza; Klenke, Frank; Hofstetter, Willy (October 2020). Noggin as a regulator of bone remodelling. Bone reports, 13, p. 100460. Elsevier 10.1016/j.bonr.2020.100460

Rieben, Robert; Hofstetter, Wilhelm (17 November 2017). Wo die kranken Mäuse leben (Interview mit Prof. Dr. Wilhelm Hofstetter und Prof. Dr. Robert Rieben). Neue Zürcher Zeitung NZZ, p. 55. Verlag Neue Zürcher Zeitung

Choy, John; Hofstetter, Wilhelm; Klenke, Frank M. (2013). RANKL immobilized on β-TCP induces and maintains osteoclast formation. Bone Abstracts, 1, PP227. Bioscientifica 10.1530/boneabs.1.PP227

Yes

Strunz, Franziska; Stähli, Christoph; Heverhagen, Johannes T; Hofstetter, Wilhelm; Egli, Rainer J (2024). Gadolinium-Based Contrast Agents and Free Gadolinium Inhibit Differentiation and Activity of Bone Cell Lineages. Investigative radiology, 59(7), pp. 495-503. Lippincott Williams & Wilkins 10.1097/RLI.0000000000001049

Strunz, Franziska; Gentil-Perret, Saskia; Siegrist, Mark; Bohner, Marc; Saulacic, Nikola; Hofstetter, Wilhelm (2024). Bisphosphonates do not affect healing of a critical-size defect in estrogen-deficient mice. Bone reports, 20(101739) Elsevier 10.1016/j.bonr.2024.101739

Santoni, Bastien Le Gars; Niggli, Luzia; Dolder, Silvia; Loeffel, Olivier; Sblendorio, Gabrielle; Maazouz, Yassine; Alexander, Duncan; Heuberger, Roman; Stähli, Christoph; Döbelin, Nicola; Bowen, Paul; Hofstetter, Wilhelm; Bohner, Marc (2023). Influence of the sintering atmosphere on the physico-chemical properties and the osteoclastic resorption of β-tricalcium phosphate cylinders. Acta biomaterialia, 169, pp. 566-578. Elsevier 10.1016/j.actbio.2023.08.012

Zaugg, Jonas; Pujol Giménez, Jonai; Cabra, Romina Silvia; Hofstetter, Wilhelm; Hediger, Matthias; Albrecht, Christiane (2022). New Insights into the Physiology of Iron Transport: An Interdisciplinary Approach. CHIMIA, 76(12), pp. 996-1004. 10.2533/chimia.2022.996

Verouti, Sophia N; Pujol-Giménez, Jonai; Bermudez-Lekerika, Paola; Scherler, Laeticia; Bhardwaj, Rajesh; Thomas, Aurélien; Lenglet, Sébastien; Siegrist, Mark; Hofstetter, Willy; Fuster, Daniel G; Hediger, Matthias A; Escher, Geneviève; Vogt, Bruno (2022). The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance. Frontiers in physiology, 13, p. 912277. Frontiers Research Foundation 10.3389/fphys.2022.912277

Schnyder, Daniela; Albano, Giuseppe; Kucharczyk, Patrycja; Dolder, Silvia; Siegrist, Mark; Anderegg, Manuel; Pathare, Ganesh; Hofstetter, Wilhelm; Baron, Roland; Fuster, Daniel G. (2021). Deletion of the sodium/hydrogen exchanger 6 causes low bone volume in adult mice. Bone, 153, p. 116178. Elsevier 10.1016/j.bone.2021.116178

Brigger, Daniel; Riether, Carsten; van Brummelen, Robin; Mosher, Kira I; Shiu, Alicia; Ding, Zhaoqing; Zbären, Noemi; Gasser, Pascal; Guntern, Pascal; Yousef, Hanadie; Castellano, Joseph M; Storni, Federico; Graff-Radford, Neill; Britschgi, Markus; Grandgirard, Denis; Hinterbrandner, Magdalena; Siegrist, Mark; Moullan, Norman; Hofstetter, Wilhelm; Leib, Stephen L.; ... (2020). Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nature metabolism, 2(8), pp. 688-702. Springer Nature 10.1038/s42255-020-0228-3

Saulacic, Nikola; Muñoz, Fernando; Kobayashi, Eizaburo; Chappuis, Vivianne; Gonzáles-Cantalapiedra, Antonio; Hofstetter, Wilhelm (2020). Effects of local application of alendronate on early healing of extraction socket in dogs. Clinical oral investigations, 24(4), pp. 1579-1589. Springer-Verlag 10.1007/s00784-019-03031-7

May, Rahel D.; Frauchiger, Daniela A.; Albers, Christoph E.; Hofstetter, Wilhelm; Gantenbein, Benjamin (2020). Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype. Neurospine, 17(1), pp. 77-87. Korean Spinal Neurosurgery Society 10.14245/ns.2040002.001

May, Rahel Deborah; Frauchiger, Daniela Angelika; Albers, Christoph Emmanuel; Tekari, Adel; Benneker, Lorin Michael; Klenke, Frank Michael; Hofstetter, Wilhelm; Gantenbein, Benjamin (2019). Application of Cytokines of the Bone Morphogenetic Protein (BMP) Family in Spinal Fusion - Effects on the Bone, Intervertebral Discs, and Mesenchymal Stromal Cells. Current stem cell research & therapy, 14(8), pp. 618-643. Bentham Science Publishers 10.2174/1574888X14666190628103528

Zhao, Weitian; Michalik, David; Ferguson, Stephen; Hofstetter, Wily; Lemaître, Jacques; von Rechenberg, Brigitte; Bowen, Paul (2019). Rapid evaluation of bioactive Ti-based surfaces using an in vitro titration method. Nature communications, 10(1), p. 2062. Springer Nature 10.1038/s41467-019-09673-1

Gallo, Marta; Le Gars Santoni, Bastien; Douillard, Thierry; Zhang, Fei; Gremillard, Laurent; Dolder, Silvia; Hofstetter, Willy; Meille, Sylvain; Bohner, Marc; Chevalier, Jérôme; Tadier, Solène (2019). Effect of grain orientation and magnesium doping on β-tricalcium phosphate resorption behavior. Acta biomaterialia, 89, pp. 391-402. Elsevier 10.1016/j.actbio.2019.02.045

May, Rahel D.; Frauchiger, Daniela A.; Albers, Christoph E.; Benneker, Lorin M.; Hofstetter, Wilhelm; Gantenbein, Benjamin (2019). Stimulation of intervertebral disc cells in alginate bead culture with bone morphogenetic protein 2 and/or L51P. In: 7th International Congress on Biotechnologies for Spinal Surgery (BioSpine7). 3-5 April.

May, Rahel Deborah; Frauchiger, D.A.; Albers, Christoph E.; Benneker, Lorin M.; Hofstetter, Wilhelm; Gantenbein, Benjamin (2019). Stimulation of intervertebral disc cells in alginate bead culture with bone morphogenetic protein 2 and/or L51P. In: TERMIS EU chapter meeting. Rhodes, Greece. 27th-31s tMay.

Hauser, Michel; Siegrist, Mark; Denzer, Alain; Saulacic, Nikola; Grosjean, Joël; Bohner, Marc; Hofstetter, Wilhelm (2018). Bisphosphonates reduce biomaterial turnover in healing of critical-size rat femoral defects. Journal of orthopaedic surgery, 26(3), p. 2309499018802487. Hong Kong University Press 10.1177/2309499018802487

Moor, Matthias B; Ramakrishnan, Suresh K; Legrand, Finola; Dolder, Silvia; Siegrist, Mark; Durussel, Fanny; Centeno, Gabriel; Firsov, Dmitri; Hynes, Nancy E; Hofstetter, Wilhelm; Bonny, Olivier (2018). Redox-Dependent Bone Alkaline Phosphatase Dysfunction Drives Part of the Complex Bone Phenotype in Mice Deficient for Memo1. JBMR plus, 2(4), pp. 195-205. Wiley 10.1002/jbm4.10034

Hauser, Michel; Siegrist, Mark; Keller, Irene; Hofstetter, Wilhelm (2018). Healing of fractures in osteoporotic bones in mice treated with bisphosphonates - A transcriptome analysis. Bone, 112, pp. 107-119. Elsevier 10.1016/j.bone.2018.04.017

Uster, Stephanie Sarah; Matos Coelho, Fernanda; Aeberli, Daniel; Stein, Jens Volker; Hofstetter, Wilhelm; Engelhardt, Britta; Seitz, Michael (2018). TNFα blockade mediates bone protection in antigen-induced arthritis by reducing osteoclast precursor supply. Bone, 107, pp. 56-65. Elsevier 10.1016/j.bone.2017.10.020

Schaller, Benoît; Saulacic, Nikola; Beck, Stefan; Imwinkelried, Thomas; Liu, Edwin Wei Yang; Nakahara, Ken; Hofstetter, Wilhelm; Iizuka, Tateyuki (2017). Osteosynthesis of partial rib osteotomy in a miniature pig model using human standard-sized magnesium plate/screw systems: Effect of cyclic deformation on implant integrity and bone healing. Journal of cranio-maxillo-facial surgery, 45(6), pp. 862-871. Elsevier 10.1016/j.jcms.2017.03.018

Zhang, Shengye; Wotzkow Alvarez, Carlos; Bongoni, Anjan K; Shaw-Boden, Jane; Siegrist, Mark; Taddeo, Adriano; Blank, Fabian; Hofstetter, Wilhelm; Rieben, Robert (2017). Role of the plasma cascade systems in ischemia/reperfusion injury of bone. Bone, 97, pp. 278-286. Elsevier 10.1016/j.bone.2016.12.007

Ruef, Nina; Dolder, Silvia; Aeberli, Daniel; Seitz, Michael; Balani, Deepak; Hofstetter, Wilhelm (2017). Granulocyte-macrophage colony-stimulating factor-dependent CD11c-positive cells differentiate into active osteoclasts. Bone, 97, pp. 267-277. Elsevier 10.1016/j.bone.2017.01.036

Albano, Giuseppe; Dolder, Silvia; Siegrist, Mark; Mercier-Zuber, Annie; Auberson, Muriel; Stoudmann, Candice; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2017). Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1). Pflügers Archiv : European journal of physiology, 469(2), pp. 225-233. Springer 10.1007/s00424-016-1923-5

Saulacic, Nikola; Nakahara, Ken; Iizuka, Tateyuki; Haga-Tsujimura, Maiko; Hofstetter, Wilhelm; Scolozzi, Paolo (2016). Comparison of two protocols of periosteal distraction osteogenesis in a rabbit calvaria model. Journal of biomedical materials research. Part B - applied biomaterials, 104(6), pp. 1121-1131. John Wiley & Sons 10.1002/jbm.b.33461

Xie, Wenjie; Dolder, Silvia; Siegrist, Mark; Wetterwald, Antoinette; Hofstetter, Wilhelm (2016). Glutamate Receptor Agonists and Glutamate Transporter Antagonists Regulate Differentiation of Osteoblast Lineage Cells. Calcified tissue international, 99(2), pp. 142-154. Springer 10.1007/s00223-016-0129-3

Xie, Wenjie; Lorenz, Sebastian; Dolder, Silvia; Hofstetter, Wilhelm (2016). Extracellular Iron is a Modulator of the Differentiation of Osteoclast Lineage Cells. Calcified tissue international, 98(3), pp. 275-283. Springer 10.1007/s00223-015-0087-1

Schaller, Benoît; Saulacic, Nikola; Imwinkelried, Thomas; Beck, Stefan; Liu, Edwin Wei Yang; Gralla, Jan; Nakahara, Ken; Hofstetter, Wilhelm; Iizuka, Tateyuki (2016). In vivo degradation of magnesium plate/screw osteosynthesis implant systems: Soft and hard tissue response in a calvarial model in miniature pigs. Journal of cranio-maxillo-facial surgery, 44(3), pp. 309-317. Elsevier 10.1016/j.jcms.2015.12.009

Aeberli, Daniel; Kamgang, Richard; Balani, Deepak; Hofstetter, Wilhelm; Villiger, Peter; Seitz, Michael (2016). Regulation of peripheral classical and non-classical monocytes on infliximab treatment in patients with rheumatoid arthritis and ankylosing spondylitis. RMD open, 2(1), e000079. BMJ Publishing Group 10.1136/rmdopen-2015-000079

Schaller, Benoît; Saulacic, Nikola; Beck, Stefan; Imwinkelried, Thomas; Goh, Bee Tin; Nakahara, Ken; Hofstetter, Wilhelm; Iizuka, Tateyuki (2016). In vivo degradation of a new concept of magnesium-based rivet-screws in the minipig mandibular bone. Materials science & engineering C, 69, pp. 247-254. Elsevier 10.1016/j.msec.2016.06.085

Albano, Giuseppe; Moor, Matthias; Dolder, Silvia; Siegrist, Mark; Wagner, Carsten A.; Biber, Jürg; Hernando, Nati; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2015). Sodium-Dependent Phosphate Transporters in Osteoclast Differentiation and Function. PLoS ONE, 10(4), e0125104. Public Library of Science 10.1371/journal.pone.0125104

Tekari, Adel; Luginbuehl, Reto; Hofstetter, Wilhelm; Egli, Rainer (2015). Transforming growth factor beta signaling is essential for the autonomous formation of cartilage-like tissue by expanded chondrocytes. PLoS ONE, 10(3), e0120857. Public Library of Science 10.1371/journal.pone.0120857

Choy, John; Albers, Christoph; Siebenrock, Klaus-Arno; Dolder, Silvia; Hofstetter, Wilhelm; Klenke, Frank M. (2014). Incorporation of RANKL promotes osteoclast formation and osteoclast activity on β-TCP ceramics. Bone, 69, pp. 80-88. Elsevier 10.1016/j.bone.2014.09.013

Tekari, Adel; Luginbuehl, Reto; Hofstetter, Wilhelm; Egli, Rainer (2014). Chondrocytes expressing intracellular collagen type II enter the cell cycle and co-express collagen type I in monolayer culture. Journal of orthopaedic research, 32(11), pp. 1503-1511. Wiley 10.1002/jor.22690

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Leunig, M.; Jüni, P.; Werlen, S.; Limacher, A.; Nüesch, E.; Pfirrmann, C. W.; Trelle, S.; Odermatt, A.; Hofstetter, Wilhelm; Ganz, R.; Reichenbach, Stephan (2013). Prevalence of cam and pincer-type deformities on hip MRI in an asymptomatic young Swiss female population: a cross-sectional study. Osteoarthritis and cartilage, 21(4), pp. 544-550. Elsevier 10.1016/j.joca.2013.01.003

Albers, Christoph E; Hofstetter, Wilhelm; Siebenrock, Klaus A; Landmann, Regine; Klenke, Frank M. (2013). In vitro cytotoxicity of silver nanoparticles on osteoblasts and osteoclasts at antibacterial concentrations. Nanotoxicology, 7(1), pp. 30-36. London: Informa Healthcare 10.3109/17435390.2011.626538

Hofstetter, Wilhelm; Sehr, Harald; De Wild, Michael; Portenier, Jeannette; Gobrecht, Jens; Hunziker, Ernst Bruno (2013). Modulation of human osteoblasts by metal surface chemistry. Journal of biomedical materials research. Part A, 101(8), pp. 2355-2364. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.34541

Balani, Deepak; Aeberli, Daniel; Hofstetter, Willy; Seitz, Michael (2012). Interleukin-17A stimulates granulocyte-macrophage colony-stimulating factor release by murine osteoblasts in the presence of 1,25-dihydroxyvitamin D(3) and inhibits murine osteoclast development in vitro. Arthritis & rheumatism, 65(2), pp. 236-246. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.37762

Reichenbach, Stephan; Leunig, Michael; Werlen, Stefan; Nüesch, Eveline; Pfirrmann, Christian W; Bonel, Harald; Odermatt, Alex; Hofstetter, Willy; Ganz, Reinhold; Jüni, Peter (2011). Association between cam-type deformities and magnetic resonance imaging-detected structural hip damage: a cross-sectional study in young men. Arthritis & rheumatism, 63(12), pp. 4023-4030. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.30589

Wernike, E; Montjovent, MO; Liu, Y; Wismeijer, D; Hunziker, EB; Siebenrock, KA; Hofstetter, W; Klenke, FM (2010). VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo. European cells & materials eCM, 19, pp. 30-40. Aberystwyth (UK): University of Wales

Hofstetter, Willy; Siegrist, Mark; Simonin, Alexandre; Bonny, Olivier; Fuster, Daniel G (2010). Sodium/hydrogen exchanger NHA2 in osteoclasts: subcellular localization and role in vitro and in vivo. Bone, 47(2), pp. 331-340. New York, N.Y.: Elsevier 10.1016/j.bone.2010.04.605

Bastian, Johannes Dominik; Egli, RJ; Hofstetter, W; Leunig, M (2010). Chondrocyte function after osteochondral transfer: comparison of concave and plane punches. Archives of orthopaedic and trauma surgery, 130(3), pp. 341-6. Berlin: Springer-Verlag 10.1007/s00402-009-0867-z

Reichenbach, S; Jüni, P; Werlen, S; Nüesch, E; Pfirrmann, CW; Trelle, S; Odermatt, A; Hofstetter, W; Ganz, R; Leunig, M (2010). Prevalence of cam-type deformity on hip magnetic resonance imaging in young males: a cross-sectional study. Arthritis & rheumatism, 62(9), pp. 1319-1327. Hoboken, N.J.: Wiley-Blackwell 10.1002/acr.20198

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