Kuhn-Nentwig, Lucia Gerda

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Kuhn-Nentwig, Lucia; Lischer, Heidi E. L.; Pekár, Stano; Langenegger, Nicolas; Albo, Maria J.; Isaia, Marco; Nentwig, Wolfgang (2021). Linear Peptides-A Combinatorial Innovation in the Venom of Some Modern Spiders. Frontiers in Molecular Biosciences, 8, p. 705141. Frontiers 10.3389/fmolb.2021.705141


Langenegger, Nicolas; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia (2019). Spider Venom: Components, Modes of Action, and Novel Strategies in Transcriptomic and Proteomic Analyses. Toxins, 11(10) MDPI 10.3390/toxins11100611

Kuhn-Nentwig, Lucia; Langenegger, Nicolas; Heller, Manfred; Koua, Dominique; Nentwig, Wolfgang (2019). The Dual Prey-Inactivation Strategy of Spiders—In-Depth Venomic Analysis of Cupiennius salei. Toxins, 11(3) MDPI 10.3390/toxins11030167


Langenegger, Nicolas; Koua, Dominique; Schürch, Stefan; Heller, Manfred; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia (2018). Identification of a precursor processing protease from the spider Cupiennius salei essential for venom neurotoxin maturation. Journal of biological chemistry, 293(6), pp. 2079-2090. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M117.810911


Koua, Dominique Kadio; Kuhn-Nentwig, Lucia Gerda (2017). Spider Neurotoxins, Short Linear Cationic Peptides and Venom Protein Classification Improved by an Automated Competition between Exhaustive Profile HMM Classifiers. Toxins, 9(8), p. 245. MDPI 10.3390/toxins9080245


Cedeño López, Alena; Schürch, Stefan; Kämpfer, Urs; Kuhn-Nentwig, Lucia Gerda (4 September 2015). Defensin Levels in Spider Hemolymph (Unpublished). In: SCS Fall Meeting. Lausanne. 04.09.2015.

Eggs, Benjamin; Wolff, JO; Kuhn-Nentwig, Lucia Gerda; Gorb, SN; Nentwig, Wolfgang (2015). Hunting without a web: How lycosoid spiders subdue their prey. Ethology, 121(12), pp. 1166-1177. Wiley-Blackwell 10.1111/eth.12432

Biner, Olivier Felix; Trachsel, Christian; Moser, Aline Isabelle; Kopp, Lukas; Langenegger, Nicolas; Kämpfer, Urs; von Ballmoos, Christoph; Nentwig, Wolfgang; Schürch, Stefan; Schaller, Johann; Kuhn-Nentwig, Lucia Gerda (2015). Isolation, N-glycosylations and Function of a Hyaluronidase-Like Enzyme from the Venom of the Spider Cupiennius salei. PLoS ONE, 10(12), e0143963. Public Library of Science 10.1371/journal.pone.0143963

Kuhn-Nentwig, Lucia Gerda; Schaller, J; Schürch, S; Nentwig, Wolfgang (2015). Venom of Cupiennius salei (Ctenidae). In: Gopalakrishnakone, P.; Corzo, Gerardo A.; Diego-Garcia, Elia; de Lima, Maria Elena (eds.) Spider Venoms. Toxinology (pp. 1-19). Springer 10.1007/978-94-007-6646-4_12-1


Kuhn-Nentwig, Lucia Gerda; Kopp, Lukas S.; Nentwig, Wolfgang; Haenni, Beat; Streitberger, Kathrin; Schürch, Stefan; Schaller, Johann (2014). Functional differentiation of spider hemocytes by light and transmission electron microscopy, and MALDI-MS-imaging. Developmental and Comparative Immunology, 43(1), pp. 59-67. Elsevier 10.1016/j.dci.2013.10.008


Kuhn-Nentwig, Lucia Gerda; Sheynis, Tania; Kolusheva, Sofiya; Nentwig, Wolfgang (2013). N-terminal aromatic residues closely impact the cytolytic activity of cupiennin 1a, a major spider venom peptide. Toxicon, 75, pp. 177-186. Elsevier 10.1016/j.toxicon.2013.03.003

Nentwig, Wolfgang; Kuhn-Nentwig, Lucia Gerda (2013). Spider Venoms Potentially Lethal to Humans. In: Nentwig, Wolfgang (ed.) Spider Ecophysiology (pp. 253-264). Berlin: Springer 10.1007/978-3-642-33989-9_19

Nentwig, Wolfgang; Kuhn-Nentwig, Lucia Gerda (2013). The Cytotoxic Mode of Action of the Venom of Cupiennius salei (Ctenidae). In: Nentwig, Wolfgang (ed.) Spider Ecophysiology (pp. 217-228). Berlin: Springer 10.1007/978-3-642-33989-9_16

Nentwig, Wolfgang; Kuhn-Nentwig, Lucia Gerda (2013). Main Components of Spider Venoms. In: Nentwig, Wolfgang (ed.) Spider Ecophysiology (pp. 191-202). Berlin: Springer 10.1007/978-3-642-33989-9_14

Kuhn-Nentwig, Lucia Gerda; Nentwig, Wolfgang (2013). The Immune System of Spiders. In: Nentwig, Wolfgang (ed.) Spider Ecophysiology (pp. 81-91). Berlin: Springer 10.1007/978-3-642-33989-9_7


Kuhn-Nentwig, Lucia; Fedorova, Irina M; Lüscher, Benjamin P; Kopp, Lukas; Trachsel, Christian; Schaller, Johann; Vu Nguyen, Xuan Lan; Seebeck, Thomas; Streitberger, Kathrin; Nentwig, Wolfgang; Sigel, Erwin; Magazanik, Lev G (2012). A venom-derived neurotoxin, CsTx-1, from the spider Cupiennius salei exhibits cytolytic activities. Journal of biological chemistry, 287(30), pp. 25640-25649. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.339051

Trachsel, Christian; Widmer, Christine; Kämpfer, Urs; Bühr, Claudia; Baumann, Tommy; Kuhn-Nentwig, Lucia; Schürch, Stefan; Schaller, Johann; Baumann, Ulrich (2012). Structural and biochemical characterization of native and recombinant single insulin-like growth factor-binding domain protein (SIBD-1) from the Central American Hunting Spider Cupiennius salei (Ctenidae). Proteins - structure, function, and bioinformatics, 80(9), pp. 2323-2329. Hoboken, N.J.: Wiley-Blackwell 10.1002/prot.24119

Trachsel, Christian; Siegemund, Doreen; Kämpfer, Urs; Kopp, Lukas; Bühr, Claudia; Grossmann, Jonas; Lüthi, Christoph; Cunningham, Monica; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia; Schürch, Stefan; Schaller, Johann (2012). Multicomponent venom of the spider Cupiennius salei: a bioanalytical investigation applying different strategies. FEBS journal, 279(15), pp. 2683-2694. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2012.08650.x


Kuhn-Nentwig, Lucia; Largiadèr, Carlo R; Streitberger, Kathrin; Chandru, Sathyan; Baumann, Tommy; Kämpfer, Urs; Schaller, Johann; Schürch, Stefan; Nentwig, Wolfgang (2011). Purification, cDNA structure and biological significance of a single insulin-like growth factor-binding domain protein (SIBD-1) identified in the hemocytes of the spider Cupiennius salei. Insect biochemistry and molecular biology, 41(11), pp. 891-901. Amsterdam: Elsevier 10.1016/j.ibmb.2011.08.003

Kuhn-Nentwig, Lucia; Stöcklin, Reto; Nentwig, Wolfgang (2011). Venom composition and strategies in spiders: is everything possible? Advances in insect physiology, 40, pp. 1-86. London: Academic Press 10.1016/B978-0-12-387668-3.00001-5

Kuhn-Nentwig, Lucia; Willems, Jean; Seebeck, Thomas; Shalaby, Tarek; Kaiser, Marcel; Nentwig, Wolfgang (2011). Cupiennin 1a exhibits a remarkably broad, non-stereospecific cytolytic activity on bacteria, protozoan parasites, insects, and human cancer cells. Amino acids, 40(1), pp. 69-76. Wien: Springer Vienna 10.1007/s00726-009-0471-0


Baumann, Tommy; Kämpfer, Urs; Schürch, Stefan; Schaller, Johann; Largiadèr, Carlo; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia (2010). Ctenidins: antimicrobial glycine-rich peptides from the hemocytes of the spider Cupiennius salei. Cellular and molecular life sciences, 67(16), pp. 2787-2798. Basel: SP Birkhäuser Verlag Basel 10.1007/s00018-010-0364-0

Baumann, Tommy; Kuhn-Nentwig, Lucia; Largiadèr, Carlo R; Nentwig, Wolfgang (2010). Expression of defensins in non-infected araneomorph spiders. Cellular and molecular life sciences, 67(15), pp. 2643-51. Basel: SP Birkhäuser Verlag Basel 10.1007/s00018-010-0354-2


Kuhn-Nentwig, Lucia; Trachsel, Christian; Nentwig, Wolfgang (2009). Spider venom and hemolymph derived cytolytic and antimicrobial peptides. In: Howl, John; Jones, Sarah (eds.) Bioactive peptides (pp. 447-464). Boca Raton: CRC Press 10.1201/9781420061161-c19

Kuhn-Nentwig, Lucia (2009). Cytolytic and antimicrobial peptides in the venom of scorpions and spiders. In: De Lima, Maria Elena (ed.) Animal Toxins: State of the Art - Perspectives in Health and Biotechnology.


Kubista, Helmut; Mafra, Roberta; Chong, Youmie; Nicholson, Graham; Beirao, Paulo; Cruz, Jader; Boehm, Stefan; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia (2007). CSTX-1, a toxin from the venom of the hunting spider Cupiennius salei, is a selective blocker of L-type calcium channels in mammalian neurons. Neuropharmacology, 8(52), pp. 1650-1662. Orlando, Fla.: Elsevier 10.1016/j.neuropharm.2007.03.012

Kuhn-Nentwig, Lucia; Kubista, Helmut; Nentwig, Wolfgang (2007). Spider venom: A rich source of highly active molecules. CHIMIA, 61(9), p. 588. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2007.588

Pukala, Tara; Boland, Martin; Gehman, John; Kuhn-Nentwig, Lucia; Separovic, Frances; Bowie, John (2007). Solution structure and interaction of cupiennin 1a, a spider venom peptide, with phospholipid bilayers. Biochemistry, 46(11), pp. 3576-3585. Washington, D.C.: American Chemical Society 10.1021/bi062306+

Pukala, Tara; Doyle, Jason; Llewellyn, Lyndon; Kuhn-Nentwig, Lucia; Apponyi, Margit; Separovic, Frances; Bowie, John (2007). Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase. FEBS journal, 7(274), pp. 1778-1784. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2007.05726.x


Kuhn-Nentwig, Lucia Gerda (2003). Antimicrobial and cytolytic peptides of venomous arthropods. Cellular and molecular life sciences, 60(12), pp. 2651-2668. SP Birkhäuser Verlag Basel 10.1007/s00018-003-3106-8

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