Up a level |
Mills, Charlotte E; Flury, Andreas; Marmet, Cynthia; Poquet, Laura; Rimoldi, Stefano; Sartori, Claudio; Rexhaj, Emrush; Brenner, Roman; Allemann, Yves; Zimmermann, Diane; Gibson, Glenn R; Mottram, Don S; Oruna-Concha, Maria-Jose; Actis-Goretta, Lucas; Spencer, Jeremy P E (2017). Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: Two randomized, controlled, crossover intervention trials. Clinical nutrition, 36(6), pp. 1520-1529. Elsevier 10.1016/j.clnu.2016.11.013
Rexhaj, Emrush; Rimoldi, Stefano F.; Pratali, Lorenza; Brenner, Roman; Andries, Daniela; Soria, Rodrigo; Salinas Salmón, Carlos; Villena, Mercedes; Romero, Catherine; Allemann, Yves; Lovis, Alban; Heinzer, Raphaël; Sartori, Claudio; Scherrer, Urs (2016). Sleep disordered breathing and vascular function in patients with chronic mountain sickness and healthy high-altitude dwellers. Chest, 149(4), pp. 991-998. American College of Chest Physicians 10.1378/chest.15-1450
Rimoldi, Stefano; Rexhaj, Emrush; Duplain, Hervé; Urben, Sébastien; Billieux, Joël; Allemann, Yves; Romero, Catherine; Ayaviri, Alejandro; Salinas, Carlos; Villena, Mercedes; Scherrer, Urs; Sartori, Claudio (2016). Acute and Chronic Altitude-Induced Cognitive Dysfunction in Children and Adolescents. Journal of pediatrics, 169, pp. 238-243. Elsevier 10.1016/j.jpeds.2015.10.009
Sartori, Claudio; Rimoldi, Stefano; Duplain, Hervé; Stuber, Thomas; Garcin, Sophie; Rexhaj, Emrush; Allemann, Yves; Scherrer, Urs (2016). Developmental Origins of Hypoxic Pulmonary Hypertension and Systemic Vascular Dysfunction: Evidence from Humans. Advances in experimental medicine and biology, 903, pp. 17-28. Springer 10.1007/978-1-4899-7678-9_2
Rimoldi, Stefano; Sartori, Claudio; Rexhaj, Emrush; Bailey, Damian M; De Marchi, Stefano; McEneny, Jane; Von Arx, Robert; Cerny, David; Duplain, Hervé; Germond, Marc; Allemann, Yves; Scherrer, Urs (2015). Antioxidants improve vascular function in children conceived by assisted reproductive technologies: A randomized double-blind placebo-controlled trial. European journal of preventive cardiology, 22(11), pp. 1399-1407. SAGE Publications 10.1177/2047487314535117
Rimoldi, Stefano F; Ott, Sebastian Robert; Rexhaj, Emrush; de Marchi, Stefano F; Allemann, Yves; Gugger, Matthias; Scherrer, Urs; Seiler, Christian (2015). Patent Foramen Ovale Closure in Obstructive Sleep Apnea Improves Blood Pressure and Cardiovascular Function. Hypertension, 66(5), pp. 1050-1057. Lippincott Williams & Wilkins 10.1161/HYPERTENSIONAHA.115.06303
Rexhaj, Emrush; Pireva, Agim; Paoloni-Giacobino, Ariane; Allemann, Yves; Cerny, David; Dessen, Pierre; Sartori, Claudio; Scherrer, Urs; Rimoldi, Stefano (2015). Prevention of vascular dysfunction and arterial hypertension in mice generated by assisted reproductive technologies by addition of melatonin to culture media. American journal of physiology - heart and circulatory physiology, 309(7), H1151-H1156. American Physiological Society 10.1152/ajpheart.00621.2014
Rimoldi, Stefano F; Ott, Sebastian Robert; Rexhaj, Emrush; Von Arx, Robert; de Marchi, Stefano F; Brenner, Roman; Scherrer, Urs; Meier, Bernhard; Gugger, Matthias; Allemann, Yves; Seiler, Christian (2015). Effect of patent foramen ovale closure on obstructive sleep apnea. Journal of the American College of Cardiology, 65(20), pp. 2257-2258. Elsevier 10.1016/j.jacc.2015.01.062
Von Arx, Robert; Allemann, Yves; Sartori, Claudio; Rexhaj, Emrush; Cerny, David; De Marchi, Stefano; Soria, Rodrigo; Germond, Marc; Scherrer, Urs; Rimoldi, Stefano (2015). Right ventricular dysfunction in children and adolescents conceived by assisted reproductive technologies. Journal of applied physiology, 118(10), pp. 1200-1206. American Physiological Society 10.1152/japplphysiol.00533.2014
Brenner, Roman; Pratali, Lorenza; Rimoldi, Stefano; Murillo Jauregui, Carla Ximena; Soria, Rodrigo; Rexhaj, Emrush; Salinas Salmón, Carlos; Villena, Mercedes; Romero, Catherine; Sartori, Claudio; Allemann, Yves; Scherrer, Urs (2015). Exaggerated pulmonary hypertension and right ventricular dysfunction in high-altitude dwellers with patent foramen ovale. Chest, 147(4), pp. 1072-1079. American College of Chest Physicians 10.1378/chest.14-1353
Scherrer, Urs; Rexhaj, Emrush; Allemann, Yves; Sartori, Claudio; Rimoldi, Stefano (2015). Cardiovascular dysfunction in children conceived by assisted reproductive technologies. European Heart Journal, 36(25), pp. 1583-1589. Oxford University Press 10.1093/eurheartj/ehv145
Von Arx, Robert; Rexhaj, Emrush; Allemann, Yves; Moschovitis, Aris; Windecker, Stephan; Meier, Bernhard; Scherrer, Urs; Rimoldi, Stefano (2014). Lack of blood pressure-lowering effect of renal denervation in a drug-naïve patient with pronounced arterial stiffening. American journal of medicine, 127(9), e3-e4. Elsevier 10.1016/j.amjmed.2014.05.024
Rimoldi, Stefano; Scheidegger, Niklaus; Scherrer, Urs; Farese, Stefan; Rexhaj, Emrush; Moschovitis, Aris; Windecker, Stephan; Meier, Bernhard; Allemann, Yves (2014). Anatomical eligibility of the renal vasculature for catheter-based renal denervation in hypertensive patients. JACC. Cardiovascular Interventions, 7(2), pp. 187-192. Elsevier 10.1016/j.jcin.2013.10.013
Rexhaj, Emrush; Paoloni-Giacobino, Ariane; Rimoldi, Stefano F.; Fuster, Daniel Guido; Anderegg, Manuel; Somm, Emmanuel; Bouillet, Elisa; Allemann, Yves; Sartori, Claudio; Scherrer, Urs (2013). Mice generated by in vitro fertilization exhibit vascular dysfunction and shortened life span. Journal of clinical investigation, 123(12), pp. 5052-5060. American Society for Clinical Investigation 10.1172/JCI68943
Pratali, Lorenza; Allemann, Yves; Rimoldi, Stefano; Faita, Francesco; Hutter, Damian; Rexhaj, Emrush; Brenner, Roman; Bailey, Damian M; Sartori, Claudio; Salmon, Carlos Salinas; Villena, Mercedes; Scherrer, Urs; Picano, Eugenio; Sicari, Rosa (2013). RV contractility and exercise-induced pulmonary hypertension in chronic mountain sickness: a stress echocardiographic and tissue Doppler imaging study. JACC. Cardiovascular imaging, 6(12), pp. 1287-1297. Elsevier 10.1016/j.jcmg.2013.08.007
Solà, Josep; Proença, Martin; Ferrario, Damien; Porchet, Jacques-André; Falhi, Abdessamad; Grossenbacher, Olivier; Allemann, Yves; Rimoldi, Stefano F.; Sartori, Claudio (2013). Non-invasive and non-occlusive blood pressure estimation via a chest sensor. IEEE transactions on bio-medical engineering, 60(12), pp. 3505-3513. Institute of Electrical and Electronics Engineers 10.1109/TBME.2013.2272699
Engelen, Lian; Ferreira, Isabel; Stehouwer, Coen D; Boutouyrie, Pierre; Laurent, Stéphane; Allemann, Yves; Hutter, Damian; Rimoldi, Stefano; Rexhaj, Emrush; Sartori, Claudio; Scherrer, Urs (2013). Reference intervals for common carotid intima-media thickness measured with echotracking: relation with risk factors. European Heart Journal, 34(30), pp. 2368-80. Oxford University Press 10.1093/eurheartj/ehs380
Scherrer, Urs; Allemann, Yves; Rexhaj, Emrush; Rimoldi, Stefano; Sartori, Claudio (2013). Mechanisms and drug therapy of pulmonary hypertension at high altitude. High altitude medicine & biology, 14(2), pp. 126-133. Mary Ann Liebert 10.1089/ham.2013.1006
Scherrer, Urs; Rimoldi, Stefano; Rexhaj, Emrush; Stuber, Thomas; Duplain, Hervé; Garcin, Sophie; de Marchi, Stefano; Nicod, Pascal; Germond, Marc; Allemann, Yves; Sartori, Claudio (2013). Response to letters regarding article, “Systemic and pulmonary vascular dysfunction in children conceived by assisted reproductive technologies”. Circulation, 127(9), e478. Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.112.134833
Bailey, Damian M; Rimoldi, Stefano; Rexhaj, Emrush; Pratali, Lorenza; Salinas Salmòn, Carlos; Villena, Mercedes; McEneny, Jane; Young, Ian S; Nicod, Pascal; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (2013). Oxidative-nitrosative stress and systemic vascular function in highlanders with and without exaggerated hypoxemia. Chest, 143(2), pp. 444-451. American College of Chest Physicians 10.1378/chest.12-0728
Wustmann, Kerstin; Klaey, Marco; Burow, Annika; Shaw, Sidney G; Hess, Otto M; Allemann, Yves (2012). Additive effect of homocysteine- and cholesterol-lowering therapy on endothelium-dependent vasodilation in patients with cardiovascular disease. Cardiovascular therapeutics, 30(5), pp. 277-86. Oxford: Blackwell 10.1111/j.1755-5922.2011.00272.x
Rimoldi, Stefano F; Rexhaj, Emrush; Pratali, Lorenza; Bailey, Damian M; Hutter, Damian; Faita, Francesco; Salmòn, Carlos Salinas; Villena, Mercedes; Nicod, Pascal; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (2012). Systemic vascular dysfunction in patients with chronic mountain sickness. Chest, 141(1), pp. 139-46. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.11-0342
Alnima, Teba; Scheffers, Ingrid; De Leeuw, Peter W; Winkens, Bjorn; Jongen-Vancraybex, Heidi; Tordoir, Jan H M; Schmidli, Jürg; Mohaupt, Markus G; Allemann, Yves; Kroon, Abraham A (2012). Sustained acute voltage-dependent blood pressure decrease with prolonged carotid baroreflex activation in therapy-resistant hypertension. Journal of hypertension, 30(8), pp. 1665-70. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/HJH.0b013e3283551f10
Brenner, Roman; Rimoldi, Stefano F; Rexhaj, Emrush; Allemann, Yves (2012). [Arterial Hypertension - when are which combination therapies useful?]. Therapeutische Umschau, 69(5), pp. 305-13. Bern: Huber
Allemann, Yves; Stuber, Thomas; de Marchi, Stefano F.; Rexhaj, Emrush; Sartori, Claudio; Scherrer, Urs; Rimoldi, Stefano F (2012). Pulmonary artery pressure and cardiac function in children and adolescents after rapid ascent to 3,450 m. American journal of physiology - heart and circulatory physiology, 302(12), H2646-H2653. Bethesda, Md.: American Physiological Society 10.1152/ajpheart.00053.2012
Schwab, Marcos; Allemann, Yves; Rexhaj, Emrush; Rimoldi, Stefano F; Sartori, Claudio; Scherrer, Urs (2012). [Pulmonary hypertension and lung edema at high altitude. Role of endothelial dysfunction and fetal programming]. Medicina, 72(2), pp. 150-7. Buenos Aires: Sociedad Argentina de Investigación Clínica
Scherrer, Urs; Rimoldi, Stefano F; Rexhaj, Emrush; Stuber, Thomas; Duplain, Hervé; Garcin, Sophie; de Marchi, Stefano F.; Nicod, Pascal; Germond, Marc; Allemann, Yves; Sartori, Claudio (2012). Systemic and pulmonary vascular dysfunction in children conceived by assisted reproductive technologies. Circulation, 125(15), pp. 1890-1896. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.111.071183
Pratali, Lorenza; Rimoldi, Stefano F; Rexhaj, Emrush; Hutter, Damian; Faita, Francesco; Salmòn, Carlos Salinas; Villena, Mercedes; Sicari, Rosa; Picano, Eugenio; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (2012). Exercise induces rapid interstitial lung water accumulation in patients with chronic mountain sickness. Chest, 141(4), pp. 953-8. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.11-0084
Parving, Hans-Henrik; Brenner, Barry M.; McMurray, John J.V.; de Zeeuw, Dick; Haffner, Steven M.; Solomon, Scott D.; Chaturvedi, Nish; Persson, Frederik; Desai, Akshay S.; Nicolaides, Maria; Richard, Alexia; Xiang, Zhihua; Brunel, Patrick; Pfeffer, Marc A.; for the ALTITUDE, incl.; Allemann, Yves (2012). Cardiorenal End Points in a Trial of Aliskiren for Type 2 Diabetes. New England journal of medicine NEJM, 367(23), pp. 2204-2213. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMoa1208799
Solà, Josep; Chételat, Olivier; Sartori, Claudio; Allemann, Yves; Rimoldi, Stefano F (2011). Chest pulse-wave velocity: a novel approach to assess arterial stiffness. IEEE transactions on biomedical engineering, 58(1), pp. 215-23. New York, N.Y.: Institute of Electrical and Electronics Engineers IEEE 10.1109/TBME.2010.2071385
Rexhaj, Emrush; Garcin, Sophie; Rimoldi, Stefano F; Duplain, Hervé; Stuber, Thomas; Allemann, Yves; Sartori, Claudio; Scherrer, Urs (2011). Reproducibility of acute mountain sickness in children and adults: a prospective study. Pediatrics, 127(6), e1445-8. Elk Grove Village, Ill.: American Academy of Pediatrics 10.1542/peds.2010-3756
Brenner, Roman; Waeber, Bernard; Allemann, Yves (2011). Medical treatment of hypertension in Switzerland. The 2009 Swiss Hypertension Survey (SWISSHYPE). Swiss medical weekly, 141, w13169. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2011.13169
Messerli, F; Bangalore, S; Makani, H; Rimoldi, S; Allemann, Yves; White, C; Textor, S; Sleight, P (2011). Flash pulmonary oedema and bilateral renal artery stenosis: the Pickering Syndrome. European Heart Journal, 32(18), pp. 2231-2235. Oxford: Oxford University Press 10.1093/eurheartj/ehr056
Rimoldi, Stefano F; de Marchi, Stefano F; Windecker, Stephan; Meier, Bernhard; Allemann, Yves (2010). Screening renal artery angiography in hypertensive patients undergoing coronary angiography and 6-month follow-up after ad hoc percutaneous revascularization. Journal of hypertension, 28(4), pp. 842-847. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/HJH.0b013e32833510e5
Stuber, Thomas; Sartori, Claudio; Schwab, Marcos; Jayet, Pierre-Yves; Rimoldi, Stefano F; Garcin, Sophie; Thalmann, Sébastien; Spielvogel, Hilde; Salmòn, Carlos; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (2010). Exaggerated Pulmonary Hypertension During Mild Exercise in Chronic Mountain Sickness. Chest, 137(2), pp. 388-392. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.09-1355
Rimoldi, Stefano F; Sartori, Claudio; Seiler, Christian; Delacrétaz, Etienne; Mattle, Heinrich P; Scherrer, Urs; Allemann, Yves (2010). High-altitude exposure in patients with cardiovascular disease: risk assessment and practical recommendations. Progress in cardiovascular diseases, 52(6), pp. 512-24. Orlando, Fla.: Elsevier 10.1016/j.pcad.2010.03.005
Jayet, Pierre-Yves; Rimoldi, Stefano F; Stuber, Thomas; Salmòn, Carlos Salinas; Hutter, Damian; Rexhaj, Emrush; Thalmann, Sébastien; Schwab, Marcos; Turini, Pierre; Sartori-Cucchia, Céline; Nicod, Pascal; Villena, Mercedes; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (2010). Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia. Circulation, 122(5), pp. 488-94. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.110.941203
Scherrer, Urs; Rexhaj, Emrush; Jayet, Pierre-Yves; Allemann, Yves; Sartori, Claudio (2010). New insights in the pathogenesis of high-altitude pulmonary edema. Progress in cardiovascular diseases, 52(6), pp. 485-92. Orlando, Fla.: Elsevier 10.1016/j.pcad.2010.02.004
Scherrer, Urs; Allemann, Yves; Jayet, Pierre-Yves; Rexhaj, Emrush; Sartori, Claudio (2010). High altitude, a natural research laboratory for the study of cardiovascular physiology and pathophysiology. Progress in cardiovascular diseases, 52(6), pp. 451-5. Orlando, Fla.: Elsevier 10.1016/j.pcad.2010.02.002
Allemann, Yves; Scherrer, Urs (2010). High-altitude medicine: important for trekkers and mountaineers, essential for progress in medicine. Progress in cardiovascular diseases, 52(6), pp. 449-50. Orlando, Fla.: Elsevier 10.1016/j.pcad.2010.02.006
Rimoldi, Stefano F; Yuzefpolskaya, Melana; Allemann, Yves; Messerli, Franz (2009). Flash pulmonary edema. Progress in cardiovascular diseases, 52(3), pp. 249-59. Orlando, Fla.: Elsevier 10.1016/j.pcad.2009.10.002
Wustmann, Kerstin; Kucera, Jan P; Scheffers, Ingrid; Mohaupt, Markus; Kroon, Abraham A; de Leeuw, Peter W; Schmidli, Jürg; Allemann, Yves; Delacrétaz, Etienne (2009). Effects of chronic baroreceptor stimulation on the autonomic cardiovascular regulation in patients with drug-resistant arterial hypertension. Hypertension, 54(3), pp. 530-6. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1161/HYPERTENSIONAHA.109.134023
Bloch, Jonathan; Duplain, Hervé; Rimoldi, Stefano F; Stuber, Thomas; Kriemler, Susi; Allemann, Yves; Sartori, Claudio; Scherrer, Urs (2009). Prevalence and time course of acute mountain sickness in older children and adolescents after rapid ascent to 3450 meters. Pediatrics, 123(1), pp. 1-5. Elk Grove Village, Ill.: American Academy of Pediatrics 10.1542/peds.2008-0200
Schwab, Marcos; Jayet, Pierre-Yves; Stuber, Thomas; Salinas, Carlos E; Bloch, Jonathan; Spielvogel, Hilde; Villena, Mercedes; Allemann, Yves; Sartori, Claudio; Scherrer, Urs (2008). Pulmonary-artery pressure and exhaled nitric oxide in Bolivian and Caucasian high altitude dwellers. High altitude medicine & biology, 9(4), pp. 295-9. Larchmont, N.Y.: Mary Ann Liebert 10.1089/ham.2008.1057
Stuber, Thomas; Sartori, Claudio; Salmòn, Carlos Salinas; Hutter, Damian; Thalmann, Sébastien; Turini, Pierre; Jayet, Pierre-Yves; Schwab, Marcos; Sartori-Cucchia, Céline; Villena, Mercedes; Scherrer, Urs; Allemann, Yves (2008). Respiratory nitric oxide and pulmonary artery pressure in children of aymara and European ancestry at high altitude. Chest, 134(5), pp. 996-1000. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.08-0854
Allemann, Yves; Fraile, Belen; Lambert, Michel; Barbier, Michaela; Ferber, Philippe; Izzo, Joseph L (2008). Efficacy of the combination of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy: the Exforge in Failure after Single Therapy (EX-FAST) study. Journal of clinical hypertension, 10(3), pp. 185-94. Hoboken, N.J.: Wiley-Blackwell 10.1111/j.1751-7176.2008.07516.x
Sartori, Claudio; Allemann, Yves; Scherrer, Urs (2007). Pathogenesis of pulmonary edema: learning from high-altitude pulmonary edema. Respiratory physiology & neurobiology, 159(3), pp. 338-49. Kidlington, UK: Elsevier 10.1016/j.resp.2007.04.006
Schwab, Marcos; Jayet, Pierre-Yves; Allemann, Yves; Sartori, Claudio; Scherrer, Urs (2007). [High altitude pulmonary edema. An experiment of nature to study the underlying mechanisms of hypoxic pulmonary hypertension and pulmonary edema in humans]. Medicina, 67(1), pp. 71-81. Buenos Aires: Sociedad Argentina de Investigación Clínica
Scherrer, Urs; Turini, Pierre; Thalmann, Sébastien; Hutter, Damian; Salmon, Carlos Salinas; Stuber, Thomas; Shaw, Sidney; Jayet, Pierre-Yves; Sartori-Cucchial, Céline; Villena, Mercedes; Allemann, Yves; Sartori, Claudio (2006). Pulmonary hypertension in high-altitude dwellers: novel mechanisms, unsuspected predisposing factors. Advances in experimental medicine and biology, 588, pp. 277-291. Wien: Springer
Allemann, Yves; Hutter, Damian; Lipp, Ernst; Sartori, Claudio; Duplain, Hervé; Egli, Marc; Cook, Stéphane; Scherrer, Urs; Seiler, Christian (2006). Patent foramen ovale and high-altitude pulmonary edema. JAMA - the journal of the American Medical Association, 296(24), pp. 2954-8. Chicago, Ill.: American Medical Association 10.1001/jama.296.24.2954
Meyer, Katharina; Steiner, Roger; Lastayo, Paul; Lippuner, Kurt; Allemann, Yves; Eberli, Franz; Schmid, Jean; Saner, Hugo; Hoppeler, Hans (2003). Eccentric exercise in coronary patients: central hemodynamic and metabolic responses. Medicine and science in sports and exercise, 35(7), pp. 1076-82. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1249/01.MSS.0000074580.79648.9D
Aeschbacher, Beat C.; Hutter, Damian Marco; Fuhrer, Jürg; Weidmann, Peter; Delacrétaz, Etienne; Allemann, Yves (2001). Diastolic dysfunction precedes myocardial hypertrophy in the development of hypertension. American journal of hypertension, 14(2), pp. 106-113. Oxford University Press 10.1016/S0895-7061(00)01245-0
Rimoldi, Stefano; Rexhaj, Emrush; Villena, Mercedes; Salmon, Carlos Salinas; Allemann, Yves; Scherrer, Urs; Sartori, Claudio (2016). Novel Insights into Cardiovascular Regulation in Patients with Chronic Mountain Sickness. In: Hypoxia Translation in Progress. Advances in Experimental Medicine and Biology: Vol. 903 (pp. 83-100). Springer 10.1007/978-1-4899-7678-9_6
Sartori, Claudio; Rimoldi, Stefano; Rexhaj, Emrush; Allemann, Yves; Scherrer, Urs (2016). Epigenetics in Cardiovascular Regulation. In: Roach, Robert C.; Hackett, Peter H.; Wagner, Peter D. (eds.) Hypoxia Translation in Progress. Advances in Experimental Medicine and Biology: Vol. 903 (pp. 55-62). Springer 10.1007/978-1-4899-7678-9_4