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Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Lou, Shaoke; Cotter, Kellie A.; Li, Tianxiao; Liang, Jin; Mohsen, Hussein; Liu, Jason; Zhang, Jing; Cohen, Sandra; Xu, Jinrui; Yu, Haiyuan; Rubin, Mark A.; Gerstein, Mark (2019). GRAM: A GeneRAlized Model to predict the molecular effect of a non-coding variant in a cell-type specific manner. PLoS genetics, 15(8), e1007860. Public Library of Science 10.1371/journal.pgen.1007860
Cotter, Kellie Anne; Rubin, Mark Andrew (2018). Sequence of events in prostate cancer. Nature, 560(7720), pp. 557-559. Macmillan Journals Ltd. 10.1038/d41586-018-06029-5
Romanel, Alessandro; Garritano, Sonia; Stringa, Blerta; Blattner, Mirjam; Dalfovo, Davide; Chakravarty, Dimple; Soong, David; Cotter, Kellie Anne; Petris, Gianluca; Dhingra, Priyanka; Gasperini, Paola; Cereseto, Anna; Elemento, Olivier; Sboner, Andrea; Khurana, Ekta; Inga, Alberto; Rubin, Mark Andrew; Demichelis, Francesca (2017). Inherited determinants of early recurrent somatic mutations in prostate cancer. Nature communications, 8(1), p. 48. Nature Publishing Group 10.1038/s41467-017-00046-0
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Auguste, Aurélie; Blanc-Durand, Félix; Deloger, Marc; Le Formal, Audrey; Bareja, Rohan; Wilkes, David C; Richon, Catherine; Brunn, Béatrice; Caron, Olivier; Devouassoux-Shisheboran, Mojgan; Gouy, Sébastien; Morice, Philippe; Bentivegna, Enrica; Sboner, Andrea; Elemento, Olivier; Rubin, Mark A; Pautier, Patricia; Genestie, Catherine; Cyrta, Joanna and Leary, Alexandra (2020). Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond SMARCA4 Mutations: A Comprehensive Genomic Analysis. Cells, 9(6) MDPI 10.3390/cells9061496
Abida, Wassim; Cyrta, Joanna; Heller, Glenn; Prandi, Davide; Armenia, Joshua; Coleman, Ilsa; Cieslik, Marcin; Benelli, Matteo; Robinson, Dan; Van Allen, Eliezer M; Sboner, Andrea; Fedrizzi, Tarcisio; Mosquera, Juan Miguel; Robinson, Brian D; De Sarkar, Navonil; Kunju, Lakshmi P; Tomlins, Scott; Wu, Yi Mi; Nava Rodrigues, Daniel; Loda, Massimo; ... (2019). Genomic correlates of clinical outcome in advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(23), pp. 11428-11436. National Academy of Sciences NAS 10.1073/pnas.1902651116
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Rubin, Mark A.; Demichelis, Francesca (2019). The Genomics of Prostate Cancer: A Historic Perspective. Cold Spring Harbor perspectives in medicine, 9(3) Cold Spring Harbor Laboratory Press 10.1101/cshperspect.a034942
Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0
Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Reyna, Matthew A; Haan, David; Paczkowska, Marta; Verbeke, Lieven P C; Vazquez, Miguel; Kahraman, Abdullah; Pulido-Tamayo, Sergio; Barenboim, Jonathan; Wadi, Lina; Dhingra, Priyanka; Shrestha, Raunak; Getz, Gad; Lawrence, Michael S; Pedersen, Jakob Skou; Rubin, Mark Andrew; Wheeler, David A; Brunak, Søren; Izarzugaza, Jose M G; Khurana, Ekta; Marchal, Kathleen; ... (2020). Pathway and network analysis of more than 2500 whole cancer genomes. Nature communications, 11(1), p. 729. Nature Publishing Group 10.1038/s41467-020-14367-0
Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0
Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0
Rubin, Mark; Largiadèr, Carlo; Staub, Timo (2020). Das Bern Center for Precision Medicine (BCPM). Schweizer Krebsbulletin / Bulletin suisse du cancer(01/20), pp. 48-50. Bern: Istituto oncologico della Svizzera Italiana
Arriaga, Juan M.; Panja, Sukanya; Alshalalfa, Mohammed; Zhao, Junfei; Zou, Min; Giacobbe, Arianna; Madubata, Chioma J.; Kim, Jaime Yeji; Rodriguez, Antonio; Coleman, Ilsa; Virk, Renu K.; Hibshoosh, Hanina; Ertunc, Onur; Ozbek, Büşra; Fountain, Julia; Jeffrey Karnes, R.; Luo, Jun; Antonarakis, Emmanuel S.; Nelson, Peter S.; Feng, Felix Y.; ... (2020). A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance. Nature ancer, 1(11), pp. 1082-1096. Springer Nature 10.1038/s43018-020-00125-0
Rubin, Mark A.; Bristow, Robert G; Thienger, Phillip D.; Dive, Caroline; Imielinski, Marcin (2020). Impact of Lineage Plasticity to and from a Neuroendocrine Phenotype on Progression and Response in Prostate and Lung Cancers. Molecular cell, 80(4), pp. 562-577. Cell Press 10.1016/j.molcel.2020.10.033
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Fine, Samson W; Trpkov, Kiril; Amin, Mahul B; Algaba, Ferran; Aron, Manju; Baydar, Dilek E; Beltran, Antonio Lopez; Brimo, Fadi; Cheville, John C; Colecchia, Maurizio; Comperat, Eva; Costello, Tony; da Cunha, Isabela Werneck; Delprado, Warick; DeMarzo, Angelo M; Giannico, Giovanna A; Gordetsky, Jennifer B; Guo, Charles C; Hansel, Donna E; Hirsch, Michelle S; ... (2020). Practice patterns related to prostate cancer grading: results of a 2019 Genitourinary Pathology Society clinician survey. (In Press). Urologic oncology Elsevier 10.1016/j.urolonc.2020.08.027
Thienger, Phillip; Rubin, Mark A. (2020). SETting Up for Epigenetic Regulation of Advanced Prostate Cancer. Cancer cell, 38(3), pp. 309-311. Cell Press 10.1016/j.ccell.2020.08.009
Lotan, Tamara L; Tomlins, Scott A; Bismar, Tarek A; Van der Kwast, Theodorus H; Grignon, David; Egevad, Lars; Kristiansen, Glen; Pritchard, Colin C; Rubin, Mark A; Bubendorf, Lukas (2020). Report From the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers. I. Molecular Biomarkers in Prostate Cancer. The American journal of surgical pathology, 44(7), e15-e29. Wolters Kluwer Health 10.1097/PAS.0000000000001450
Epstein, Jonathan I; Amin, Mahul B; Fine, Samson W; Algaba, Ferran; Aron, Manju; Baydar, Dilek E; Beltran, Antonio Lopez; Brimo, Fadi; Cheville, John C; Colecchia, Maurizio; Comperat, Eva; da Cunha, Isabela Werneck; Delprado, Warick; DeMarzo, Angelo M; Giannico, Giovanna A; Gordetsky, Jennifer B; Guo, Charles C; Hansel, Donna E; Hirsch, Michelle S; Huang, Jiaoti; ... (2020). The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer. (In Press). Archives of pathology & laboratory medicine College of American Pathologists 10.5858/arpa.2020-0015-RA
Auguste, Aurélie; Blanc-Durand, Félix; Deloger, Marc; Le Formal, Audrey; Bareja, Rohan; Wilkes, David C; Richon, Catherine; Brunn, Béatrice; Caron, Olivier; Devouassoux-Shisheboran, Mojgan; Gouy, Sébastien; Morice, Philippe; Bentivegna, Enrica; Sboner, Andrea; Elemento, Olivier; Rubin, Mark A; Pautier, Patricia; Genestie, Catherine; Cyrta, Joanna and Leary, Alexandra (2020). Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond SMARCA4 Mutations: A Comprehensive Genomic Analysis. Cells, 9(6) MDPI 10.3390/cells9061496
Pisapia, David J; Ohara, Kentaro; Bareja, Rohan; Wilkes, David C; Hissong, Erika; Croyle, Jaclyn A; Kim, Joon-Hyung; Saab, Jad; MacDonald, Theresa Y; Beg, Shaham; O'Reilly, Catherine; Kudman, Sarah; Rubin, Mark A; Elemento, Olivier; Sboner, Andrea; Greenfield, Jeffrey; Mosquera, Juan Miguel (2020). Fusions involving BCOR and CREBBP are rare events in infiltrating glioma. Acta neuropathologica communications, 8(1), p. 80. BioMed Central 10.1186/s40478-020-00951-4
Rubin, Mark; Largiadèr, Carlo; Staub, Timo (2020). Das Bern Center for Precision Medicine (BCPM). Schweizer Krebsbulletin / Bulletin suisse du cancer(01/20), pp. 48-50. Bern: Istituto oncologico della Svizzera Italiana
Reyna, Matthew A; Haan, David; Paczkowska, Marta; Verbeke, Lieven P C; Vazquez, Miguel; Kahraman, Abdullah; Pulido-Tamayo, Sergio; Barenboim, Jonathan; Wadi, Lina; Dhingra, Priyanka; Shrestha, Raunak; Getz, Gad; Lawrence, Michael S; Pedersen, Jakob Skou; Rubin, Mark Andrew; Wheeler, David A; Brunak, Søren; Izarzugaza, Jose M G; Khurana, Ekta; Marchal, Kathleen; ... (2020). Pathway and network analysis of more than 2500 whole cancer genomes. Nature communications, 11(1), p. 729. Nature Publishing Group 10.1038/s41467-020-14367-0
Arriaga, Juan M.; Panja, Sukanya; Alshalalfa, Mohammed; Zhao, Junfei; Zou, Min; Giacobbe, Arianna; Madubata, Chioma J.; Kim, Jaime Yeji; Rodriguez, Antonio; Coleman, Ilsa; Virk, Renu K.; Hibshoosh, Hanina; Ertunc, Onur; Ozbek, Büşra; Fountain, Julia; Jeffrey Karnes, R.; Luo, Jun; Antonarakis, Emmanuel S.; Nelson, Peter S.; Feng, Felix Y.; ... (2020). A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance. Nature ancer, 1(11), pp. 1082-1096. Springer Nature 10.1038/s43018-020-00125-0
Beltran, Himisha; Hruszkewycz, Andrew; Scher, Howard I; Hildesheim, Jeffrey; Isaacs, Jennifer; Yu, Evan Y; Kelly, Kathleen; Lin, Daniel; Dicker, Adam; Arnold, Julia; Hecht, Toby; Wicha, Max; Sears, Rosalie; Rowley, David; White, Richard; Gulley, James L; Lee, John; Diaz Meco, Maria; Small, Eric J; Shen, Michael; ... (2019). The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance. Clinical cancer research, 25(23), pp. 6916-6924. American Association for Cancer Research 10.1158/1078-0432.CCR-19-1423
Persi, Erez; Prandi, Davide; Wolf, Yuri I; Pozniak, Yair; Barnabas, Georgina D; Levanon, Keren; Barshack, Iris; Barbieri, Christopher; Gasperini, Paola; Beltran, Himisha; Faltas, Bishoy M; Rubin, Mark A.; Geiger, Tamar; Koonin, Eugene V; Demichelis, Francesca; Horn, David (2019). Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(34), pp. 16987-16996. National Academy of Sciences NAS 10.1073/pnas.1908790116
Lou, Shaoke; Cotter, Kellie A.; Li, Tianxiao; Liang, Jin; Mohsen, Hussein; Liu, Jason; Zhang, Jing; Cohen, Sandra; Xu, Jinrui; Yu, Haiyuan; Rubin, Mark A.; Gerstein, Mark (2019). GRAM: A GeneRAlized Model to predict the molecular effect of a non-coding variant in a cell-type specific manner. PLoS genetics, 15(8), e1007860. Public Library of Science 10.1371/journal.pgen.1007860
Robinson, Brian D; Vlachostergios, Panagiotis J; Bhinder, Bhavneet; Liu, Weisi; Li, Kailyn; Moss, Tyler J; Bareja, Rohan; Park, Kyung; Tavassoli, Peyman; Cyrta, Joanna; Tagawa, Scott T; Nanus, David M; Beltran, Himisha; Molina, Ana M; Khani, Francesca; Miguel Mosquera, Juan; Xylinas, Evanguelos; Shariat, Shahrokh F; Scherr, Douglas S; Rubin, Mark A.; ... (2019). Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling. Nature Communications, 10(1), p. 2977. Springer Nature 10.1038/s41467-019-10873-y
Shen, Michael M; Rubin, Mark Andrew (2019). Prostate Cancer Research at the Crossroads. Cold Spring Harbor perspectives in medicine, 9(7) Cold Spring Harbor Laboratory Press 10.1101/cshperspect.a036277
Abida, Wassim; Cyrta, Joanna; Heller, Glenn; Prandi, Davide; Armenia, Joshua; Coleman, Ilsa; Cieslik, Marcin; Benelli, Matteo; Robinson, Dan; Van Allen, Eliezer M; Sboner, Andrea; Fedrizzi, Tarcisio; Mosquera, Juan Miguel; Robinson, Brian D; De Sarkar, Navonil; Kunju, Lakshmi P; Tomlins, Scott; Wu, Yi Mi; Nava Rodrigues, Daniel; Loda, Massimo; ... (2019). Genomic correlates of clinical outcome in advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(23), pp. 11428-11436. National Academy of Sciences NAS 10.1073/pnas.1902651116
Augello, Michael A; Liu, Deli; Deonarine, Lesa D; Robinson, Brian D; Huang, Dennis; Stelloo, Suzan; Blattner, Mirjam; Doane, Ashley S; Wong, Elissa W P; Chen, Yu; Rubin, Mark A.; Beltran, Himisha; Elemento, Olivier; Bergman, Andries M; Zwart, Wilbert; Sboner, Andrea; Dephoure, Noah; Barbieri, Christopher E (2019). CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis. Cancer cell, 35(4), 603-617.e8. Cell Press 10.1016/j.ccell.2019.03.001
Lee, Rachel S; Zhang, Luxi; Berger, Adeline; Lawrence, Mitchell G; Song, Jiangning; Niranjan, Birunthi; Davies, Rebecca G; Lister, Natalie L; Sandhu, Shahneen K; Rubin, Mark A.; Risbridger, Gail P; Taylor, Renea A; Rickman, David S; Horvath, Lisa G; Daly, Roger J (2019). Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target. Neoplasia, 21(4), pp. 389-400. Elsevier 10.1016/j.neo.2019.02.005
Rubin, Mark A.; Demichelis, Francesca (2019). The Genomics of Prostate Cancer: A Historic Perspective. Cold Spring Harbor perspectives in medicine, 9(3) Cold Spring Harbor Laboratory Press 10.1101/cshperspect.a034942
Skvortsova, Ksenia; Masle-Farquhar, Etienne; Luu, Phuc-Loi; Song, Jenny Z; Qu, Wenjia; Zotenko, Elena; Gould, Cathryn M; Du, Qian; Peters, Timothy J; Colino-Sanguino, Yolanda; Pidsley, Ruth; Nair, Shalima S; Khoury, Amanda; Smith, Grady C; Miosge, Lisa A; Reed, Joanne H; Kench, James G; Rubin, Mark A.; Horvath, Lisa; Bogdanovic, Ozren; ... (2019). DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns. Cancer cell, 35(2), 297-314.e8. Cell Press 10.1016/j.ccell.2019.01.004
Beltran, Himisha; Oromendia, Clara; Danila, Daniel C; Montgomery, Bruce; Hoimes, Christopher; Szmulewitz, Russell Z; Vaishampayan, Ulka; Armstrong, Andrew J; Stein, Mark; Pinski, Jacek; Mosquera, Juan M; Sailer, Verena; Bareja, Rohan; Romanel, Alessandro; Gumpeni, Naveen; Sboner, Andrea; Dardenne, Etienne; Puca, Loredana; Prandi, Davide; Rubin, Mark A.; ... (2019). A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers. Clinical cancer research, 25(1), pp. 43-51. American Association for Cancer Research 10.1158/1078-0432.CCR-18-1912
Fernandez, Evan M; Eng, Kenneth; Beg, Shaham; Beltran, Himisha; Faltas, Bishoy M; Mosquera, Juan Miguel; Nanus, David M; Pisapia, David J; Rao, Rema A; Robinson, Brian D; Rubin, Mark A.; Elemento, Olivier; Sboner, Andrea; Shah, Manish A; Song, Wei (2019). Cancer-Specific Thresholds Adjust for Whole Exome Sequencing-based Tumor Mutational Burden Distribution. JCO precision oncology, 3 American Society of Clinical Oncology 10.1200/PO.18.00400
Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0
Boysen, Gunther; Rodrigues, Daniel N; Rescigno, Pasquale; Seed, George; Dolling, David; Riisnaes, Ruth; Crespo, Mateus; Zafeiriou, Zafeiris; Sumanasuriya, Semini; Bianchini, Diletta; Hunt, Joanne; Moloney, Deirdre; Perez-Lopez, Raquel; Tunariu, Nina; Miranda, Susana; Figueiredo, Inês; Ferreira, Ana; Christova, Rossitza; Gil, Veronica; Aziz, Sara; ... (2018). SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity. Clinical cancer research, 24(22), pp. 5585-5593. American Association for Cancer Research 10.1158/1078-0432.CCR-18-0937
Cotter, Kellie Anne; Rubin, Mark Andrew (2018). Sequence of events in prostate cancer. Nature, 560(7720), pp. 557-559. Macmillan Journals Ltd. 10.1038/d41586-018-06029-5
Hopkins, Benjamin D; Pauli, Chantal; Du, Xing; Wang, Diana G; Li, Xiang; Wu, David; Amadiume, Solomon C; Goncalves, Marcus D; Hodakoski, Cindy; Lundquist, Mark R; Bareja, Rohan; Ma, Yan; Harris, Emily M; Sboner, Andrea; Beltran, Himisha; Rubin, Mark Andrew; Mukherjee, Siddhartha; Cantley, Lewis C (2018). Suppression of insulin feedback enhances the efficacy of PI3K inhibitors. Nature, 560(7719), pp. 499-503. Macmillan Journals Ltd. 10.1038/s41586-018-0343-4
Triscott, Joanna; Rubin, Mark A. (2018). Prostate Power Play: Does Accelerate -Deficient Cancer Progression? Cancer discovery, 8(6), pp. 682-685. American Association for Cancer Research 10.1158/2159-8290.CD-18-0369
Mateo, Joaquin; Cheng, Heather H; Beltran, Himisha; Dolling, David; Xu, Wen; Pritchard, Colin C; Mossop, Helen; Rescigno, Pasquale; Perez-Lopez, Raquel; Sailer, Verena; Kolinsky, Michael; Balasopoulou, Ada; Bertan, Claudia; Nanus, David M; Tagawa, Scott T; Thorne, Heather; Montgomery, Bruce; Carreira, Suzanne; Sandhu, Shahneen; Rubin, Mark Andrew; ... (2018). Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study. European urology, 73(5), pp. 687-693. Elsevier 10.1016/j.eururo.2018.01.010
Sailer, Verena; Schiffman, Marc H; Kossai, Myriam; Cyrta, Joanna; Beg, Shaham; Sullivan, Brian; Pua, Bradley B; Lee, Kyungmouk Steve; Talenfeld, Adam D; Nanus, David M; Tagawa, Scott T; Robinson, Brian D; Rao, Rema A; Pauli, Chantal; Bareja, Rohan; Beltran, Luis S; Sigaras, Alexandros; Eng, Kenneth Wa; Elemento, Olivier; Sboner, Andrea; ... (2018). Bone biopsy protocol for advanced prostate cancer in the era of precision medicine. Cancer, 124(5), pp. 1008-1015. John Wiley & Sons 10.1002/cncr.31173
Shoag, Jonathan; Liu, Deli; Blattner, Mirjam; Sboner, Andrea; Park, Kyung; Deonarine, Lesa; Robinson, Brian D; Mosquera, Juan Miguel; Chen, Yu; Rubin, Mark Andrew; Barbieri, Christopher E (2018). SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG. Journal of clinical investigation, 128(1), pp. 381-386. American Society for Clinical Investigation 10.1172/JCI96551
McNair, Christopher; Xu, Kexin; Mandigo, Amy C; Benelli, Matteo; Leiby, Benjamin; Rodrigues, Daniel; Lindberg, Johan; Gronberg, Henrik; Crespo, Mateus; De Laere, Bram; Dirix, Luc; Visakorpi, Tapio; Li, Fugen; Feng, Felix Y; de Bono, Johann; Demichelis, Francesca; Rubin, Mark Andrew; Brown, Myles; Knudsen, Karen E (2018). Differential impact of RB status on E2F1 reprogramming in human cancer. Journal of clinical investigation, 128(1), pp. 341-358. American Society for Clinical Investigation 10.1172/JCI93566
D'Alfonso, Timothy M; Subramaniyam, Shivakumar; Ginter, Paula S; Mosquera, Juan Miguel; Croyle, Jaclyn; Liu, Yi-Fang; Rubin, Mark Andrew; Shin, Sandra J (2018). Characterization of CD34-deficient myofibroblastomas of the breast. The breast journal, 24(1), pp. 55-61. Wiley 10.1111/tbj.12835
Rubin, Mark Andrew; Demichelis, Francesca (2018). The Genomics of Prostate Cancer: emerging understanding with technologic advances. Modern pathology, 31(S1), S1-11. Nature Publishing Group 10.1038/modpathol.2017.166
Shukla, Shipra; Cyrta, Joanna; Murphy, Devan A; Walczak, Edward G; Ran, Leili; Agrawal, Praveen; Xie, Yuanyuan; Chen, Yuedan; Wang, Shangqian; Zhan, Yu; Li, Dan; Wong, Elissa W P; Sboner, Andrea; Beltran, Himisha; Mosquera, Juan Miguel; Sher, Jessica; Cao, Zhen; Wongvipat, John; Koche, Richard P; Gopalan, Anuradha; ... (2017). Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance. Cancer cell, 32(6), 792-806.e7. Cell Press 10.1016/j.ccell.2017.10.008
Lee, D; Fontugne, J; Gumpeni, N; Park, K; MacDonald, T Y; Robinson, B D; Sboner, A; Rubin, Mark Andrew; Mosquera, J M; Barbieri, C E (2017). Molecular alterations in prostate cancer and association with MRI features. Prostate cancer and prostatic diseases, 20(4), pp. 430-435. Nature 10.1038/pcan.2017.33
Pauli, C; Moch, H; Rubin, Mark Andrew (2017). [Establishment of a living biobank : Improved guidance of precision cancer care with in vitro and in vivo cancer models]. Der Pathologe, 38(Suppl 2), pp. 160-168. Springer 10.1007/s00292-017-0346-1
Wilkes, David C; Sailer, Verena; Xue, Hui; Cheng, Hongwei; Collins, Colin C; Gleave, Martin; Wang, Yuzhuo; Demichelis, Francesca; Beltran, Himisha; Rubin, Mark Andrew; Rickman, David S (2017). A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents. Cold Spring Harbor molecular case studies, 3(5) Cold Spring Harbor Laboratory Press 10.1101/mcs.a001487
Dai, Xiangpeng; Gan, Wenjian; Li, Xiaoning; Wang, Shangqian; Zhang, Wei; Huang, Ling; Liu, Shengwu; Zhong, Qing; Guo, Jianping; Zhang, Jinfang; Chen, Ting; Shimizu, Kouhei; Beca, Francisco; Blattner, Mirjam; Vasudevan, Divya; Buckley, Dennis L; Qi, Jun; Buser, Lorenz; Liu, Pengda; Inuzuka, Hiroyuki; ... (2017). Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nature medicine, 23(9), pp. 1063-1071. Nature Publishing Group 10.1038/nm.4378
Minciacchi, V R; Zijlstra, A; Rubin, Mark Andrew; Di Vizio, D (2017). Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed? Prostate cancer and prostatic diseases, 20(3), pp. 251-258. Nature 10.1038/pcan.2017.7
Huang, Franklin W; Mosquera, Juan Miguel; Garofalo, Andrea; Oh, Coyin; Baco, Maria; Amin-Mansour, Ali; Rabasha, Bokang; Bahl, Samira; Mullane, Stephanie A; Robinson, Brian D; Aldubayan, Saud; Khani, Francesca; Karir, Beerinder; Kim, Eejung; Chimene-Weiss, Jeremy; Hofree, Matan; Romanel, Alessandro; Osborne, Joseph R; Kim, Jong Wook; Azabdaftari, Gissou; ... (2017). Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer discovery, 7(9), pp. 973-983. American Association for Cancer Research 10.1158/2159-8290.CD-16-0960
Wang, Hui; Barbieri, Christopher E; He, Jintang; Gao, Yuqian; Shi, Tujin; Wu, Chaochao; Schepmoes, Athena A; Fillmore, Thomas L; Chae, Sung-Suk; Huang, Dennis; Mosquera, Juan Miguel; Qian, Wei-Jun; Smith, Richard D; Srivastava, Sudhir; Kagan, Jacob; Camp, David G; Rodland, Karin D; Rubin, Mark Andrew; Liu, Tao (2017). Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics. Journal of translational medicine, 15(1), p. 175. BioMed Central 10.1186/s12967-017-1276-7
Sanda, Martin G; Feng, Ziding; Howard, David H; Tomlins, Scott A; Sokoll, Lori J; Chan, Daniel W; Regan, Meredith M; Groskopf, Jack; Chipman, Jonathan; Patil, Dattatraya H; Salami, Simpa S; Scherr, Douglas S; Kagan, Jacob; Srivastava, Sudhir; Thompson, Ian M; Siddiqui, Javed; Fan, Jing; Joon, Aron Y; Bantis, Leonidas E; Rubin, Mark Andrew; ... (2017). Association Between Combined TMPRSS2:ERG and PCA3 RNA Urinary Testing and Detection of Aggressive Prostate Cancer. JAMA oncology, 3(8), pp. 1085-1093. American Medical Association 10.1001/jamaoncol.2017.0177
Dhingra, Priyanka; Martinez-Fundichely, Alexander; Berger, Adeline; Huang, Franklin W; Forbes, Andre Neil; Liu, Eric Minwei; Liu, Deli; Sboner, Andrea; Tamayo, Pablo; Rickman, David S; Rubin, Mark Andrew; Khurana, Ekta (2017). Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network. Genome biology, 18(1), p. 141. BioMed Central Ltd. 10.1186/s13059-017-1266-3
Zou, Min; Toivanen, Roxanne; Mitrofanova, Antonina; Floch, Nicolas; Hayati, Sheida; Sun, Yanping; Le Magnen, Clémentine; Chester, Daniel; Mostaghel, Elahe A; Califano, Andrea; Rubin, Mark Andrew; Shen, Michael M; Abate-Shen, Cory (2017). Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer. Cancer discovery, 7(7), pp. 736-749. American Association for Cancer Research 10.1158/2159-8290.CD-16-1174
Romanel, Alessandro; Garritano, Sonia; Stringa, Blerta; Blattner, Mirjam; Dalfovo, Davide; Chakravarty, Dimple; Soong, David; Cotter, Kellie Anne; Petris, Gianluca; Dhingra, Priyanka; Gasperini, Paola; Cereseto, Anna; Elemento, Olivier; Sboner, Andrea; Khurana, Ekta; Inga, Alberto; Rubin, Mark Andrew; Demichelis, Francesca (2017). Inherited determinants of early recurrent somatic mutations in prostate cancer. Nature communications, 8(1), p. 48. Nature Publishing Group 10.1038/s41467-017-00046-0
Huang, Linda; Fernandes, Helen; Zia, Hamid; Tavassoli, Peyman; Rennert, Hanna; Pisapia, David; Imielinski, Marcin; Sboner, Andrea; Rubin, Mark Andrew; Kluk, Michael; Elemento, Olivier (2017). The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretations. Journal of the American Medical Informatics Association, 24(3), pp. 513-519. Oxford University Press 10.1093/jamia/ocw148
Imielinski, Marcin; Rubin, Mark Andrew (2017). Prostate cancer: Clinical hallmarks in whole cancer genomes. Nature reviews - clinical oncology, 14(5), pp. 265-266. Nature Publishing Group 10.1038/nrclinonc.2017.45
Pauli, Chantal; Hopkins, Benjamin D; Prandi, Davide; Shaw, Reid; Fedrizzi, Tarcisio; Sboner, Andrea; Sailer, Verena; Augello, Michael; Puca, Loredana; Rosati, Rachele; McNary, Terra J; Churakova, Yelena; Cheung, Cynthia; Triscott, Joanna Catherine Caprio; Pisapia, David; Rao, Rema; Mosquera, Juan Miguel; Robinson, Brian; Faltas, Bishoy M; Emerling, Brooke E; ... (2017). Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine. Cancer discovery, 7(5), pp. 462-477. American Association for Cancer Research 10.1158/2159-8290.CD-16-1154
Sailer, Verena; Pauli, Chantal; Merzier, Elyze C; Mosquera, Juan Miguel; Beltran, Himisha; Rubin, Mark Andrew; Rao, Rema A (2017). On-site Cytology for Development of Patient-Derived Three-dimensional Organoid Cultures - A Pilot Study. Anticancer research, 37(4), pp. 1569-1573. International Inst. of Anticancer Research 10.21873/anticanres.11486
Blattner, Mirjam; Liu, Deli; Robinson, Brian D; Huang, Dennis; Poliakov, Anton; Gao, Dong; Nataraj, Srilakshmi; Deonarine, Lesa D; Augello, Michael A; Sailer, Verena; Ponnala, Lalit; Ittmann, Michael; Chinnaiyan, Arul M; Sboner, Andrea; Chen, Yu; Rubin, Mark Andrew; Barbieri, Christopher E (2017). SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling. Cancer cell, 31(3), pp. 436-451. Cell Press 10.1016/j.ccell.2017.02.004
Mateo, Joaquin; Boysen, Gunther; Barbieri, Christopher E; Bryant, Helen E; Castro, Elena; Nelson, Pete S; Olmos, David; Pritchard, Colin C; Rubin, Mark Andrew; de Bono, Johann S (2017). DNA Repair in Prostate Cancer: Biology and Clinical Implications. European urology, 71(3), pp. 417-425. Elsevier 10.1016/j.eururo.2016.08.037
Barbieri, Christopher E; Chinnaiyan, Arul M; Lerner, Seth P; Swanton, Charles; Rubin, Mark Andrew (2017). The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics. European urology, 71(2), pp. 237-246. Elsevier 10.1016/j.eururo.2016.08.024
Villers, Arnauld; Rubin, Mark Andrew (2017). Re: Prognostic Significance of Percentage and Architectural Types of Contemporary Gleason Pattern 4 Prostate Cancer in Radical Prostatectomy. European urology, 71(2), p. 301. Elsevier 10.1016/j.eururo.2016.09.017
Mu, Ping; Zhang, Zeda; Benelli, Matteo; Karthaus, Wouter R; Hoover, Elizabeth; Chen, Chi-Chao; Wongvipat, John; Ku, Sheng-Yu; Gao, Dong; Cao, Zhen; Shah, Neel; Adams, Elizabeth J; Abida, Wassim; Watson, Philip A; Prandi, Davide; Huang, Chun-Hao; de Stanchina, Elisa; Lowe, Scott W; Ellis, Leigh; Beltran, Himisha; ... (2017). SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer. Science, 355(6320), pp. 84-88. American Association for the Advancement of Science 10.1126/science.aah4307
Bishop, Jennifer L; Thaper, Daksh; Vahid, Sepideh; Davies, Alastair; Ketola, Kirsi; Kuruma, Hidetoshi; Jama, Randy; Nip, Ka Mun; Angeles, Arkhjamil; Johnson, Fraser; Wyatt, Alexander W; Fazli, Ladan; Gleave, Martin E; Lin, Dong; Rubin, Mark Andrew; Collins, Colin C; Wang, Yuzhuo; Beltran, Himisha; Zoubeidi, Amina (2017). The Master Neural Transcription Factor BRN2 Is an Androgen Receptor-Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer. Cancer discovery, 7(1), pp. 54-71. American Association for Cancer Research 10.1158/2159-8290.CD-15-1263
Rubin, Mark; Largiadèr, Carlo; Staub, Timo (2020). Das Bern Center for Precision Medicine (BCPM). Schweizer Krebsbulletin / Bulletin suisse du cancer(01/20), pp. 48-50. Bern: Istituto oncologico della Svizzera Italiana
Rubin, Mark A.; Bristow, Robert G; Thienger, Phillip D.; Dive, Caroline; Imielinski, Marcin (2020). Impact of Lineage Plasticity to and from a Neuroendocrine Phenotype on Progression and Response in Prostate and Lung Cancers. Molecular cell, 80(4), pp. 562-577. Cell Press 10.1016/j.molcel.2020.10.033
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Thienger, Phillip; Rubin, Mark A. (2020). SETting Up for Epigenetic Regulation of Advanced Prostate Cancer. Cancer cell, 38(3), pp. 309-311. Cell Press 10.1016/j.ccell.2020.08.009
Triscott, Joanna; Rubin, Mark A. (2018). Prostate Power Play: Does Accelerate -Deficient Cancer Progression? Cancer discovery, 8(6), pp. 682-685. American Association for Cancer Research 10.1158/2159-8290.CD-18-0369
Pauli, Chantal; Hopkins, Benjamin D; Prandi, Davide; Shaw, Reid; Fedrizzi, Tarcisio; Sboner, Andrea; Sailer, Verena; Augello, Michael; Puca, Loredana; Rosati, Rachele; McNary, Terra J; Churakova, Yelena; Cheung, Cynthia; Triscott, Joanna Catherine Caprio; Pisapia, David; Rao, Rema; Mosquera, Juan Miguel; Robinson, Brian; Faltas, Bishoy M; Emerling, Brooke E; ... (2017). Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine. Cancer discovery, 7(5), pp. 462-477. American Association for Cancer Research 10.1158/2159-8290.CD-16-1154
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
