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Janowczyk, Andrew; Zlobec, Inti; Walker, Cedric; Berezowska, Sabina; Huschauer, Viola; Tinguely, Marianne; Kupferschmid, Joel; Mallet, Thomas; Merkler, Doron; Kreutzfeldt, Mario; Gasic, Radivoje; Rau, Tilman T; Mazzucchelli, Luca; Eyberg, Isgard; Cathomas, Gieri; Mertz, Kirsten D; Koelzer, Viktor H; Soldini, Davide; Jochum, Wolfram; Rössle, Matthias; ... (2024). Swiss digital pathology recommendations: results from a Delphi process conducted by the Swiss Digital Pathology Consortium of the Swiss Society of Pathology. Virchows Archiv, 485(1), pp. 13-30. Springer 10.1007/s00428-023-03712-5
Neto, Pedro C; Montezuma, Diana; Oliveira, Sara P; Oliveira, Domingos; Fraga, João; Monteiro, Ana; Monteiro, João; Ribeiro, Liliana; Gonçalves, Sofia; Reinhard, Stefan; Zlobec, Inti; Pinto, Isabel M; Cardoso, Jaime S (2024). An interpretable machine learning system for colorectal cancer diagnosis from pathology slides. NPJ precision oncology, 8(56) Springer Nature 10.1038/s41698-024-00539-4
Gander, Thi Thuy Hang; Schläfli, Joëlle; Baumgartner, Johanna; Walthert, Sabrina; Genitsch, Vera; van Geest, Geert; Galván, José A; Cardozo, Carmen; Graham Martinez, Cristina; Grans, Mona; Muth, Sabine; Bruggmann, Rémy; Probst, Hans Christian; Gabay, Cem; Freigang, Stefan (2023). Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis. Immunity, 56(8), 1743-1760.e9. Cell Press 10.1016/j.immuni.2023.06.023
Grüter, Basil E; Canzanella, Gwendoline; Hägler, Joshua; Rey, Jeannine; Wanderer, Stefan; von Gunten, Michael; Galván, José A; Grobholz, Rainer; Widmer, Hans-Rudolf; Remonda, Luca; Andereggen, Lukas; Marbacher, Serge (2023). Topographic distribution of inflammation factors in a healing aneurysm. Journal of neuroinflammation, 20(1), p. 182. BioMed Central 10.1186/s12974-023-02863-1
Le‐Trilling, Vu Thuy Khanh; Ebel, Jana‐Fabienne; Baier, Franziska; Wohlgemuth, Kerstin; Pfeifer, Kai Robin; Mookhoek, Aart; Krebs, Philippe; Determann, Madita; Katschinski, Benjamin; Adamczyk, Alexandra; Lange, Erik; Klopfleisch, Robert; Lange, Christian M.; Sokolova, Viktoriya; Trilling, Mirko; Westendorf, Astrid M. (2023). Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cells. European journal of immunology, 53(2), e2249940. Wiley 10.1002/eji.202249940
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Zeng, Qiqun; Saghafinia, Sadegh; Chryplewicz, Agnieszka; Fournier, Nadine; Christe, Lucine; Xie, Yu-Qing; Guillot, Jeremy; Yucel, Simge; Li, Pumin; Galván, José A; Karamitopoulou, Eva; Zlobec, Inti; Ataca, Dalya; Gallean, Fleuriane; Zhang, Peng; Rodríguez-Calero, José Antonio; Rubin, Mark; Tichet, Mélanie; Homicsko, Krisztian and Hanahan, Douglas (2022). Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion. Science, 378(6621), eabl7207. American Association for the Advancement of Science 10.1126/science.abl7207
Noti, Luca; Galván, José; Dawson, Heather; Lugli, Alessandro; Kirsch, Richard; Assarzadegan, Naziheh; Messenger, David; Krebs, Philippe; Berger, Martin D; Zlobec, Inti (2022). A combined spatial score of granzyme B and CD68 surpasses CD8 as an independent prognostic factor in TNM stage II colorectal cancer. BMC cancer, 22(1), p. 987. BioMed Central 10.1186/s12885-022-10048-x
Ten Hoorn, Sanne; Waasdorp, Cynthia; van Oijen, Martijn G H; Damhofer, Helene; Trinh, Anne; Zhao, Lan; Smits, Lisanne J H; Bootsma, Sanne; van Pelt, Gabi W; Mesker, Wilma E; Mol, Linda; Goey, Kaitlyn K H; Koopman, Miriam; Medema, Jan Paul; Tuynman, Jurriaan B; Zlobec, Inti; Punt, Cornelis J A; Vermeulen, Louis; Bijlsma, Maarten F (2022). Serum-based measurements of stromal activation through ADAM12 associate with poor prognosis in colorectal cancer. BMC cancer, 22(1), p. 394. BioMed Central 10.1186/s12885-022-09436-0
Nguyen, Huu-Giao; Lundström, Oxana; Blank, Annika; Dawson, Heather; Lugli, Alessandro; Anisimova, Maria; Zlobec, Inti (2022). Image-based assessment of extracellular mucin-to-tumor area predicts consensus molecular subtypes (CMS) in colorectal cancer. Modern pathology, 35(2), pp. 240-248. Springer Nature 10.1038/s41379-021-00894-8
Bräutigam, Konstantin; Reinhard, Stefan; Galván, José A.; Wartenberg, Martin; Hewer, Ekkehard; Schürch, Christian M. (2022). Systematic Investigation of SARS-CoV-2 Receptor Protein Distribution along Viral Entry Routes in Humans. Respiration, 101(6), pp. 610-618. Karger 10.1159/000521317
Halloy, François; Brönnimann, Paulina; Hall, Jonathan; Schümperli, Daniel (2022). Analysis of Oligonucleotide Biodistribution and Metabolization in Experimental Animals. Methods in molecular biology, 2537, pp. 335-350. Springer 10.1007/978-1-0716-2521-7_19
Zlobec, Inti; Bächli, Melanie; Galuppini, Francesca; Berger, Martin D.; Dawson, Heather E.; Nagtegaal, Iris D; Lugli, Alessandro (2021). Refining the ITBCC tumor budding scoring system with a "zero-budding" category in colorectal cancer. Virchows Archiv, 479(6), pp. 1085-1090. Springer 10.1007/s00428-021-03090-w
Karamitopoulou, Eva; Andreou, Andreas; Pahud de Mortanges, Aurélie; Tinguely, Marianne; Gloor, Beat; Perren, Aurel (2021). PD-1/PD-L1-Associated Immunoarchitectural Patterns Stratify Pancreatic Cancer Patients into Prognostic/Predictive Subgroups. Cancer immunology research, 9(12), pp. 1439-1450. American Association for Cancer Research 10.1158/2326-6066.CIR-21-0144
Saghafinia, Sadegh; Homicsko, Krisztian; Di Domenico, Annunziata; Wullschleger, Stephan; Perren, Aurel; Marinoni, Ilaria; Ciriello, Giovanni; Michael, Iacovos P; Hanahan, Douglas (2021). Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression. Cancer discovery, 11(10), pp. 2638-2657. American Association for Cancer Research 10.1158/2159-8290.CD-20-1637
Kandasamy, Palanivel; Zlobec, Inti; Nydegger, Damian T.; Pujol-Gimenez, Jonai; Bhardwaj, Rajesh; Shirasawa, Senji; Tsunoda, Toshiyuki; Hediger, Matthias A. (2021). Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1. Molecular oncology, 15(10), pp. 2782-2800. Wiley 10.1002/1878-0261.12999
Haddad, Tariq Sami; Lugli, Alessandro; Aherne, Susan; Barresi, Valeria; Terris, Benoît; Bokhorst, John-Melle; Brockmoeller, Scarlet Fiona; Cuatrecasas, Miriam; Simmer, Femke; El-Zimaity, Hala; Fléjou, Jean-François; Gibbons, David; Cathomas, Gieri; Kirsch, Richard; Kuhlmann, Tine Plato; Langner, Cord; Loughrey, Maurice B; Riddell, Robert; Ristimäki, Ari; Kakar, Sanjay; ... (2021). Improving tumor budding reporting in colorectal cancer: a Delphi consensus study. Virchows Archiv, 479(3), pp. 459-469. Springer 10.1007/s00428-021-03059-9
Georges, Nadine DF; Oberli, Beatrice; Rau, Tilman; Galván, José; Nagtegaal, Iris D; Dawson, Heather; Blank, Annika; Kohler, Andreas; Lugli, Alessandro; Zlobec, Inti (2021). Tumour budding and CD8+ T-cells: "attackers" and "defenders" in rectal cancer with and without neoadjuvant chemoradiotherapy. Histopathology, 78(7), pp. 1009-1018. Wiley 10.1111/his.14319
Bellanger, Anne-Pauline; Wang, Junhua; Gbaguidi-Haore, Houssein; Barrera, Coralie; Bresson-Hadni, Solange; Zlobec, Inti; Lachenmayer, Anja; Richou, Carine; Turco, Celia; Gottstein, Bruno; Millon, Laurence; Beldi, Guido (2021). Investigating new serological and tissue markers for the follow-up of patients operated for alveolar echinococcosis. Parasite immunology, 43(6), e12827. Wiley 10.1111/pim.12827
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Karamitopoulou, Evanthia; Esposito, Irene; Zlobec, Inti; Insilla, Andrea Cacciato; Wartenberg, Martin; Schaeffer, David F; Kalloger, Steve; La Rosa, Stefano; Sempoux, Christine; Ramos Centeno, Irene; Lohneis, Philipp (2021). Reproducibility of tumor budding assessment in pancreatic cancer based on a multicenter interobserver study. Virchows Archiv, 478(4), pp. 719-726. Springer 10.1007/s00428-020-02987-2
Studer, Linda; Blank, Annika; Bokhorst, John-Melle; Nagtegaal, Iris D; Zlobec, Inti; Lugli, Alessandro; Fischer, Andreas; Dawson, Heather (2021). Taking Tumour Budding to the Next Frontier - a Post-ITBCC 2016 Review. Histopathology, 78(4), pp. 476-484. Wiley 10.1111/his.14267
Guo, Yuchen; Gabola, Monica; Lattanzio, Rossano; Paul, Conception; Pinet, Valérie; Tang, Ruizhi; Turali, Hulya; Bremond, Julie; Longobardi, Ciro; Maurizy, Chloé; Da Costa, Quentin; Finetti, Pascal; Boissière-Michot, Florence; Rivière, Benjamin; Lemmers, Céline; Garnier, Séverine; Bertucci, François; Zlobec, Inti; Chebli, Karim; Tazi, Jamal; ... (2021). Cyclin A2 maintains colon homeostasis and is a prognostic factor in CRC. The journal of clinical investigation, 131(4) American Society for Clinical Investigation 10.1172/JCI131517
Lugli, Alessandro; Zlobec, Inti; Berger, Martin D.; Kirsch, Richard; Nagtegaal, Iris D (2021). Tumour budding in solid cancers. Nature reviews. Clinical oncology, 18(2), pp. 101-115. Springer Nature 10.1038/s41571-020-0422-y
Nguyen, Huu-Giao; Blank, Annika; Dawson, Heather E.; Lugli, Alessandro; Zlobec, Inti (2021). Classification of colorectal tissue images from high throughput tissue microarrays by ensemble deep learning methods. Scientific reports, 11(1), p. 2371. Springer Nature 10.1038/s41598-021-81352-y
Rau, Tilman T.; Bettschen, Eva; Büchi, Carol; Christe, Lucine; Rohner, Amanda; Müller, Michael D.; Carlson, Joseph W; Imboden, Sara; Zlobec, Inti (2021). Prognostic impact of tumor budding in endometrial carcinoma within distinct molecular subgroups. Modern pathology, 34(1), pp. 222-232. Springer Nature 10.1038/s41379-020-0626-9
April-Monn, Simon Leonhard; Wiedmer, Tabea; Skowronska, Magdalena; Maire, Renaud; Schiavo Lena, Marco; Trippel, Mafalda; Di Domenico, Annunziata; Muffatti, Francesca; Andreasi, Valentina; Capurso, Gabriele; Doglioni, Claudio; Kim-Fuchs, Corina; Gloor, Beat; Zatelli, Maria Chiara; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). 3D Primary Cell Culture: A Novel Preclinical Model For Pancreatic Neuroendocrine Tumors (PanNETs). Neuroendocrinology, 111(3), pp. 273-287. Karger 10.1159/000507669
Elvebakken, Hege; Perren, A.; Scoazec, Jean-Yves; Tang, Laura H; Federspiel, Birgitte; Klimstra, David S; Vestermark, Lene W; Ali, Abir S; Zlobec, I.; Myklebust, Tor Å; Hjortland, Geir O; Langer, Seppo W; Gronbæk, Henning; Knigge, Ulrich; Tiensuu Janson, Eva; Sorbye, Halfdan (2021). A consensus developed morphological re-evaluation of 196 high-grade gastroenteropancreatic neuroendocrine neoplasms and its clinical correlations. Neuroendocrinology, 111(9), pp. 883-894. Karger 10.1159/000511905
Burren, Sandra; Reche, Katharina; Blank, Annika; Galván, José A.; Dawson, Heather; Berger, Martin D.; Zlobec, Inti; Lugli, Alessandro (2021). RHAMM in liver metastases of stage IV colorectal cancer with mismatch-repair proficient status correlates with tumor budding, cytotoxic T-cells and PD-1/PD-L1. Pathology, research and practice, 223, p. 153486. Elsevier 10.1016/j.prp.2021.153486
Rhyner Agocs, Gaëlle; Assarzadegan, Naziheh; Kirsch, Richard; Dawson, Heather; Galván, José A.; Lugli, Alessandro; Zlobec, Inti; Berger, Martin D. (2021). LAG-3 Expression Predicts Outcome in Stage II Colon Cancer. Journal of personalized medicine, 11(8) MDPI 10.3390/jpm11080749
Jiang, Sizun; Mukherjee, Nilanjan; Bennett, Richard S; Chen, Han; Logue, James; Dighero-Kemp, Bonnie; Kurtz, Jonathan R; Adams, Ricky; Phillips, Darci; Schürch, Christian M; Goltsev, Yury; Hickey, John W; McCaffrey, Erin F; Delmastro, Alea; Chu, Pauline; Reader, J Rachel; Keesler, Rebekah I; Galván, José A.; Zlobec, Inti; Van Rompay, Koen K A; ... (2021). Rhesus Macaque CODEX Multiplexed Immunohistochemistry Panel for Studying Immune Responses During Ebola Infection. Frontiers in immunology, 12, p. 729845. Frontiers Research Foundation 10.3389/fimmu.2021.729845
Di Domenico, Annunziata; Pipinikas, Christodoulos P; Maire, Renaud S; Bräutigam, Konstantin; Simillion, Cedric; Dettmer, Matthias S; Vassella, Erik; Thirlwell, Chrissie; Perren, Aurel; Marinoni, Ilaria (2020). Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression. Communications biology, 3(1), p. 740. Springer Nature 10.1038/s42003-020-01479-y
Mlecnik, Bernhard; Bifulco, Carlo; Bindea, Gabriela; Marliot, Florence; Lugli, Alessandro; Lee, J Jack; Zlobec, Inti; Rau, Tilman T.; Berger, Martin D.; Nagtegaal, Iris D; Vink-Börger, Elisa; Hartmann, Arndt; Geppert, Carol; Kolwelter, Julie; Merkel, Susanne; Grützmann, Robert; Van den Eynde, Marc; Jouret-Mourin, Anne; Kartheuser, Alex; Léonard, Daniel; ... (2020). Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer. Journal of clinical oncology, 38(31), pp. 3638-3651. American Society of Clinical Oncology 10.1200/JCO.19.03205
Schürch, Christian M; Bhate, Salil S; Barlow, Graham L; Phillips, Darci J; Noti, Luca; Zlobec, Inti; Chu, Pauline; Black, Sarah; Demeter, Janos; McIlwain, David R; Kinoshita, Shigemi; Samusik, Nikolay; Goltsev, Yury; Nolan, Garry P (2020). Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front. Cell, 183(3), p. 838. Cell Press 10.1016/j.cell.2020.10.021
Schürch, Christian M; Bhate, Salil S; Barlow, Graham L; Phillips, Darci J; Noti, Luca; Zlobec, Inti; Chu, Pauline; Black, Sarah; Demeter, Janos; McIlwain, David R; Kinoshita, Shigemi; Samusik, Nikolay; Goltsev, Yury; Nolan, Garry P (2020). Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front. Cell, 182(5), 1341-1359.e19. Cell Press 10.1016/j.cell.2020.07.005
Contat, Caroline; Ancey, Pierre-Benoit; Zangger, Nadine; Sabatino, Silvia; Pascual, Justine; Escrig, Stéphane; Jensen, Louise; Goepfert, Christine; Lanz, Bernard; Lepore, Mario; Gruetter, Rolf; Rossier, Anouk; Berezowska, Sabina; Neppl, Christina; Zlobec, Inti; Clerc-Rosset, Stéphanie; Knott, Graham William; Rathmell, Jeffrey C; Abel, E Dale; Meibom, Anders; ... (2020). Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth. eLife, 9 eLife Sciences Publications 10.7554/eLife.53618
Fernando-Macías, Ester; Fernández-García, Maria Teresa; García-Pérez, Eva; Porrero Guerrero, Belén; López-Arévalo, Camilo; Rodríguez-Uría, Raquel; Sanz-Navarro, Sandra; Vázquez-Villa, José Fernando; Muñíz-Salgueiro, María Carmen; Suárez-Fernández, Laura; Galván Hernández, José A.; Barneo-Caragol, Clara; García-Ocaña, Marcos; de Los Toyos, Juan R; Barneo-Serra, Luis (2020). A new aggressive xenograft model of human colon cancer using cancer-associated fibroblasts. PeerJ, 8(e9045), e9045. 10.7717/peerj.9045
Unternaehrer, Julia; Grobholz, Rainer; Janowczyk, Andrew; Zlobec, Inti (2020). Current opinion, status and future development of digital pathology in Switzerland. Journal of clinical pathology, 73(6), pp. 341-346. BMJ Publishing Group 10.1136/jclinpath-2019-206155
Neppl, Christina; Zlobec, Inti; Schmid, Ralph A.; Berezowska, Sabina Anna (2020). Validation of the International Tumor Budding Consensus Conference (ITBCC) 2016 recommendation in squamous cell carcinoma of the lung-a single-center analysis of 354 cases. Modern pathology, 33(5), pp. 802-811. Springer Nature 10.1038/s41379-019-0413-7
Galván, José A.; Wiprächtiger, Julia; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Kröll, Dino; Seiler, Christian A.; Langer, Rupert (2020). Immunohistochemical analysis of the expression of cancer-associated fibroblast markers in esophageal cancer with and without neoadjuvant therapy. Virchows Archiv, 476(5), pp. 725-734. Springer 10.1007/s00428-019-02714-6
Dawson, Heather; Christe, Lucine; Eichmann, Micha; Reinhard, Stefan; Zlobec, Inti; Blank, Annika; Lugli, Alessandro (2020). Tumour Budding/T-cell infiltrates in Colorectal Cancer: Proposal of a Novel Combined Score. Histopathology, 76(4), pp. 572-580. Wiley 10.1111/his.14006
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Alday-Parejo, Begoña; Richard, François; Wörthmüller, Janine; Rau, Tilman; Galván, José A.; Desmedt, Christine; Santamaria-Martinez, Albert; Rüegg, Curzio (2020). MAGI1, a New Potential Tumor Suppressor Gene in Estrogen Receptor Positive Breast Cancer. Cancers, 12(1) MDPI AG 10.3390/cancers12010223
Bozorgtabar, Behzad; Mahapatra, Dwarikanath; Zlobec, Inti; Rau, Tilman T.; Thiran, Jean-Philippe (2020). Editorial: Computational Pathology. Frontiers in medicine, 7(245), p. 245. Frontiers 10.3389/fmed.2020.00245
Lugli, Alessandro; Zlobec, Inti (2020). The battle for prognosis at the invasive front of colorectal cancer. EBioMedicine, 58, p. 102918. Elsevier 10.1016/j.ebiom.2020.102918
Abbet, Christian; Zlobec, Inti; Bozorgtabar, Behzad; Thiran, Jean-Philippe (2020). Divide-and-Rule: Self-Supervised Learning for Survival Analysis in Colorectal Cancer. In: Martel, Anne L.; Abolmaesumi, Purang; Stoyanov, Danail; Mateus, Diana; Zuluaga, Maria A.; Zhou, S. Kevin; Racoceanu, Daniel; Joskowicz, Leo (eds.) Medical Image Computing and Computer Assisted Intervention – MICCAI 2020. Lecture Notes in Computer Science: Vol. 12265 (pp. 480-489). Cham: Springer International Publishing 10.1007/978-3-030-59722-1_46
Kappel, Sven; Stoklosa, Paulina; Hauert, Barbara; Ross-Kaschitza, Daniela; Borgström, Anna; Baur, Roland; Galván, José A.; Zlobec, Inti; Peinelt, Christine (2019). TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells. Molecular oncology, 13(11), pp. 2393-2405. FEBS Press 10.1002/1878-0261.12566
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Anso, Juan; Dür, Cilgia; Apelt, Mareike; Venail, Frederic; Scheidegger, Oliver; Seidel, Kathleen; Rohrbach, Helene; Forterre, Franck; Dettmer, Matthias S.; Zlobec, Inti; Weber, Klaus; Matulic, Marco; Zoka-Assadi, Masoud; Huth, Markus; Caversaccio, Marco; Weber, Stefan (2019). Prospective Validation of Facial Nerve Monitoring to Prevent Nerve Damage During Robotic Drilling. Frontiers in Surgery, 6(58), p. 58. Frontiers 10.3389/fsurg.2019.00058
Pastille, Eva; Wasmer, Marie-Hélène Christin; Adamczyk, Alexandra; Vu, Vivian Pham; Mager, Lukas F; Phuong, Nhi Ngo Thi; Palmieri, Vittoria; Simillion, Cedric André Marie; Hansen, Wiebke; Kasper, Stefan; Schuler, Martin; Muggli, Beat; McCoy, Kathy D; Buer, Jan; Zlobec, Inti; Westendorf, Astrid M; Krebs, Philippe (2019). The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer. Mucosal immunology, 12(4), pp. 990-1003. Nature Publishing Group 10.1038/s41385-019-0176-y
Wyss, Jacqueline; Dislich, Bastian; Kölzer, Viktor; Galván, José A.; Dawson, Heather; Hädrich, Marion; Inderbitzin, Daniel; Lugli, Alessandro; Zlobec, Inti; Berger, Martin D. (2019). Stromal PD-1/PD-L1 Expression Predicts Outcome in Colon Cancer Patients. Clinical colorectal cancer, 18(1), e20-e38. Elsevier 10.1016/j.clcc.2018.09.007
Zeng, Qiqun; Michael, Iacovos P.; Zhang, Peng; Saghafinia, Sadegh; Knott, Graham; Jiao, Wei; McCabe, Brian D.; Galván, José A.; Robinson, Hugh P. C.; Zlobec, Inti; Ciriello, Giovanni; Hanahan, Douglas (2019). Synaptic proximity enables NMDAR signalling to promote brain metastasis. Nature, 573(7775), pp. 526-531. Springer Nature 10.1038/s41586-019-1576-6
Georges, Laurent M. C.; De Wever, Olivier; Galván, José A.; Dawson, Heather; Lugli, Alessandro; Demetter, Pieter; Zlobec, Inti (2019). Cell Line Derived Xenograft Mouse Models Are a Suitable in vivo Model for Studying Tumor Budding in Colorectal Cancer. Frontiers in medicine, 6(139), p. 139. Frontiers 10.3389/fmed.2019.00139
Lytle, Nikki K.; Ferguson, L. Paige; Rajbhandari, Nirakar; Gilroy, Kathryn; Fox, Raymond G.; Deshpande, Anagha; Schürch, Christian M.; Hamilton, Michael; Robertson, Neil; Lin, Wei; Noel, Pawan; Wartenberg, Martin; Zlobec, Inti; Eichmann, Micha David; Galván, José A.; Karamitopoulou, Evanthia; Gilderman, Tami; Esparza, Lourdes Adriana; Shima, Yutaka; Spahn, Philipp; ... (2019). A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Cell, 177(3), 572-586.e22. Cell Press 10.1016/j.cell.2019.03.010
Meyer, Sara N.; Galván, José A.; Zahnd, Stefan; Sokol, Lena; Dawson, Heather; Lugli, Alessandro; Zlobec, Inti (2019). Co-expression of cytokeratin and vimentin in colorectal cancer highlights a subset of tumor buds and an atypical cancer-associated stroma. Human pathology, 87, pp. 18-27. Elsevier 10.1016/j.humpath.2019.02.002
Neppl, Christina; Keller, Manuel D; Scherz, Amina; Dorn, Patrick; Schmid, Ralph A.; Zlobec, Inti; Berezowska, Sabina (2019). Comparison of the 7th and 8th Edition of the UICC/AJCC TNM Staging System in Primary Resected Squamous Cell Carcinomas of the Lung-A Single Center Analysis of 354 Cases. Frontiers in medicine, 6(196), p. 196. Frontiers 10.3389/fmed.2019.00196
Blank, Annika; Schenker, Carla; Dawson, Heather; Beldi, Guido; Zlobec, Inti; Lugli, Alessandro (2019). Evaluation of Tumor Budding in Primary Colorectal Cancer and Corresponding Liver Metastases Based on H&E and Pancytokeratin Staining. Frontiers in medicine, 6, p. 247. Frontiers 10.3389/fmed.2019.00247
Janser, Félice A.; Ney, Patricia; Teixeira Pinto, Marta; Langer, Rupert; Tschan, Mario P. (2019). The Chick Chorioallantoic Membrane (CAM) Assay as a Three-dimensional Model to Study Autophagy in Cancer Cells. Bio-protocol, 9(13) bio-protocol 10.21769/BioProtoc.3290
Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132
Graule, Janina; Uth-Gottardi, Kristin; Fischer, Elia Luca; Centeno Ramos, Irene; Galván Hernández, José Alberto; Eichmann, Micha David; Rau, Tilman; Langer, Rupert; Dawson, Heather; Nitsche, Ulrich; Traeger, Peter; Berger, Martin Dave; Schnüriger, Beat; Hädrich, Marion; Studer, Peter; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2018). CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway. Clinical epigenetics, 10(1), p. 120. Springer 10.1186/s13148-018-0548-2
Wartenberg, Martin; Cibin, Silvia; Zlobec, Inti; Vassella, Erik; Eppenberger-Castori, Serenella; Terracciano, Luigi; Eichmann, Micha David; Worni, Mathias; Gloor, Beat; Perren, Aurel; Karamitopoulou, Evanthia (2018). Integrated Genomic and Immunophenotypic Classification of Pancreatic Cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance. Clinical cancer research, 24(18), pp. 4444-4454. American Association for Cancer Research 10.1158/1078-0432.CCR-17-3401
Karamitopoulou, Evanthia; Wartenberg, Martin; Zlobec, Inti; Cibin, Silvia; Worni, Mathias; Gloor, Beat; Lugli, Alessandro (2018). Tumour budding in pancreatic cancer revisited: validation of the ITBCC scoring system. Histopathology, 73(1), pp. 137-146. Wiley 10.1111/his.13508
Vavricka, Stephan R; Galván Hernández, José Alberto; Dawson, Heather; Soltermann, Alex; Biedermann, Luc; Scharl, Michael; Schoepfer, Alain M; Rogler, Gerhard; Prinz Vavricka, Mareike B; Terracciano, Luigi; Navarini, Alexander; Zlobec, Inti; Lugli, Alessandro; Greuter, Thomas (2018). Expression Patterns of TNFα, MAdCAM1 and STAT3 in Intestinal and Skin Manifestations of Inflammatory Bowel Disease. Journal of Crohn's & colitis, 12(3), pp. 347-354. Oxford University Press 10.1093/ecco-jcc/jjx158
Kröll, Dino; Noser, Laura; Erdem, Suna; Zlobec, Inti; Storni, Federico Lorenzo; Arnold, Dominik; Dislich, Bastian; Seiler, Christian A.; Candinas, Daniel; Langer, Rupert (2018). Application of the 8th edition of the AJCC yTNM staging system shows improved prognostication in a single center cohort of esophageal carcinomas. Surgical oncology, 27(1), pp. 100-105. Elsevier 10.1016/j.suronc.2017.12.005
Li, Leanne; Zeng, Qiqun; Bhutkar, Arjun; Galván Hernández, José Alberto; Karamitopoulou, Evanthia; Noordermeer, Daan; Peng, Mei-Wen; Piersigilli, Alessandra; Perren, Aurel; Zlobec, Inti; Robinson, Hugh; Iruela-Arispe, M. Luisa; Hanahan, Douglas (2018). GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth. Cancer cell, 33(4), 736-751.e5. Cell Press 10.1016/j.ccell.2018.02.011
Blank, Annika; Roberts, Daniel Edward; Dawson, Heather; Zlobec, Inti; Lugli, Alessandro (2018). Tumor Heterogeneity in Primary Colorectal Cancer and Corresponding Metastases. Does the Apple Fall Far From the Tree? Frontiers in medicine, 5, p. 234. Frontiers 10.3389/fmed.2018.00234
Cernea, Ana; Fernández-Martínez, Juan Luis; deAndrés-Galiana, Enrique J.; deAndrés-Galiana, Enrique J.; Galván, José A.; García Pravia, Carmen; Zhang, Jinxin (2018). Analysis of Clinical Prognostic Variables for Triple Negative Breast Cancer Histological Grading and Lymph Node Metastasis. Journal of medical informatics and decision making, 1(1), pp. 14-36. Open Access Pub 10.14302/issn.2641-5526.jmid-18-2488
Saurer, Leslie; Zysset, Daniel; Rihs, Silvia; Mager, Lukas; Gusberti, Matteo; Simillion, Cedric; Lugli, Alessandro; Zlobec, Inti; Krebs, Philippe; Müller, Christoph (2017). TREM-1 promotes intestinal tumorigenesis. Scientific Reports, 7(1), p. 14870. Nature Publishing Group 10.1038/s41598-017-14516-4
Mele, Valentina; Sokol, Lena; Kölzer, Viktor; Pfaff, Dennis; Muraro, Manuele Giuseppe; Keller, Irene; Zahnd, Stefan Patrick; Centeno Ramos, Irene; Terracciano, Luigi Maria; Dawson, Heather; Zlobec, Inti; Iezzi, Giandomenica; Lugli, Alessandro (2017). The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer. OncoTarget, 8(41), pp. 70617-70629. Impact Journals LLC 10.18632/oncotarget.19904
Marti, Nesa Magdalena; Malikova, Jana; Galván Hernández, José Alberto; Aebischer, Maude; Janner, Marco; Sumnik, Zdenek; Obermannova, Barbora; Escher, Geneviève; Perren, Aurel; Flück Pandey, Christa Emma (2017). Androgen production in pediatric adrenocortical tumors may occur via both the classic and/or the alternative backdoor pathway. Molecular and cellular endocrinology, 452, pp. 64-73. Elsevier Ireland 10.1016/j.mce.2017.05.014
Lugli, Alessandro; Kirsch, Richard; Ajioka, Yoichi; Bosman, Fred; Cathomas, Gieri; Dawson, Heather; El Zimaity, Hala; Fléjou, Jean-François; Hansen, Tine Plato; Hartmann, Arndt; Kakar, Sanjay; Langner, Cord; Nagtegaal, Iris; Puppa, Giacomo; Riddell, Robert; Ristimäki, Ari; Sheahan, Kieran; Smyrk, Thomas; Sugihara, Kenichi; Terris, Benoît; ... (2017). Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016. Modern pathology, 30(9), pp. 1299-1311. Nature Publishing Group 10.1038/modpathol.2017.46
Koelzer, Viktor H; Assarzadegan, Naziheh; Dawson, Heather; Mitrovic, Bojana; Grin, Andrea; Messenger, David E; Kirsch, Richard; Riddell, Robert H; Lugli, Alessandro; Zlobec, Inti (2017). Cytokeratin-based assessment of tumour budding in colorectal cancer: analysis in stage II patients and prospective diagnostic experience. The journal of pathology: clinical research, 3(3), pp. 171-178. Wiley 10.1002/cjp2.73
Ivanovska, Jelena; Zlobec, Inti; Forster, Stefan; Karamitopoulou, Evanthia; Dawson, Heather; Koelzer, Viktor Hendrik; Agaimy, Abbas; Garreis, Fabian; Söder, Stephan; Laqua, William; Lugli, Alessandro; Hartmann, Arndt; Rau, Tilman; Schneider-Stock, Regine (2017). Correction: DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells. OncoTarget, 8(11), pp. 18615-18616. Impact Journals LLC 10.18632/oncotarget.16154
Dislich, Bastian; Stein, Alexandra Vanessa; Seiler, Christian A.; Kröll, Dino; Berezowska, Sabina Anna; Zlobec, Inti; Galván Hernández, José Alberto; Slotta-Huspenina, Julia; Walch, Axel; Langer, Rupert (2017). Expression patterns of programmed death-ligand 1 in esophageal adenocarcinomas: comparison between primary tumors and metastases. Cancer immunology, immunotherapy, 66(6), pp. 777-786. Springer 10.1007/s00262-017-1982-2
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Marti, Nesa Magdalena; Galván, José A.; Pandey, Amit Vikram; Trippel, Mafalda; Tapia, Coya; Müller, Michel; Perren, Aurel; Flück Pandey, Christa Emma (2017). Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome. Molecular and cellular endocrinology, 441, pp. 116-123. Elsevier Ireland 10.1016/j.mce.2016.07.029
Riether, Carsten; Schürch, Christian M.; Bührer, Elias D.; Hinterbrandner, Magdalena; Huguenin, Anne-Laure; Höpner, Sabine; Zlobec, Inti; Pabst, Thomas; Radpour, Ramin; Ochsenbein, Adrian F. (2017). CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia. The Journal of experimental medicine, 214(2), pp. 359-380. Rockefeller Univ. Press 10.1084/jem.20152008
Dislich, Bastian; Stein, Alexandra Vanessa; Galván Hernández, José Alberto; Berezowska, Sabina Anna; Seiler, Christian A.; Kröll, Dino; Langer, Rupert (2017). P2.04-026 Expression Patterns of PD-L1 in Esophageal Adenocarcinomas: Comparison between Primary Tumors and Metastases. Journal of thoracic oncology, 12(1S), s1012-s1012. Elsevier 10.1016/j.jtho.2016.11.1406
Berezowska, Sabina; Galván, José A. (2017). Immunohistochemical Detection of the Autophagy Markers LC3 and p62/SQSTM1 in Formalin-Fixed and Paraffin-Embedded Tissue. In: Pellicciari, Carlo; Biggiogera, Marco (eds.) Histochemistry of Single Molecules. Methods in Molecular Biology: Vol. 1560 (pp. 189-194). New York, NY: Springer New York 10.1007/978-1-4939-6788-9_13
Centeno, Irene; Paasinen Sohns, Aino; Flury, Miriam; Galván, José A.; Zahnd, Stefan; Kölzer, Viktor H.; Sokol, Lena; Dawson, Heather E.; Lugli, Alessandro; Cathomas, Gieri; Zlobec, Inti (2017). DNA profiling of tumor buds in colorectal cancer indicates that they have the same mutation profile as the tumor from which they derive. Virchows Archiv, 470(3), pp. 341-346. Springer 10.1007/s00428-017-2071-9
Kölzer, Viktor; Sokol, Lena; Zahnd, Stefan Patrick; Christe, Lucine; Dawson, Heather; Berger, Martin Dave; Inderbitzin, Daniel; Zlobec, Inti; Lugli, Alessandro (2017). Digital analysis and epigenetic regulation of the signature of rejection in colorectal cancer. Oncoimmunology, 6(4), e1288330. Landes Bioscience 10.1080/2162402X.2017.1288330
Wartenberg, Martin; Centeno, Irene; Haemmig, Stefan; Vassella, Erik; Zlobec, Inti; Galván, José A.; Neuenschwander, Maja; Schlup, Cornelia; Gloor, Beat; Lugli, Alessandro; Perren, Aurel; Karamitopoulou, Evanthia (2016). PTEN alterations of the stromal cells characterise an aggressive subpopulation of pancreatic cancer with enhanced metastatic potential. European journal of cancer, 65, pp. 80-90. Elsevier 10.1016/j.ejca.2016.06.013
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Schafroth, Christian; Galván Hernández, José Alberto; Centeno Ramos, Irene; Kölzer, Viktor; Dawson, Heather; Sokol, Lena; Rieger, Gregor; Berger, Martin D; Hädrich, Marion; Rosenberg, Robert; Nitsche, Ulrich; Schnüriger, Beat; Langer, Rupert; Inderbitzin, Daniel; Inderbitzin, Daniel; Lugli, Alessandro; Zlobec, Inti (2015). VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer. OncoTarget, 6(39), pp. 41453-41463. Impact Journals LLC 10.18632/oncotarget.6162
Galván Hernández, José Alberto; Zlobec, Inti; Wartenberg, Martin; Lugli, Alessandro; Gloor, Beat; Perren, Aurel; Karamitopoulou, Evanthia (2015). Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer. British journal of cancer, 112(12), pp. 1944-1950. Nature Publishing Group 10.1038/bjc.2015.177
Galván Hernández, José Alberto; Helbling, Melina; Kölzer, Viktor; Tschan, Mario; Berger, Martin Dave; Hädrich, Marion; Schnüriger, Beat; Karamitopoulou, Evanthia; Dawson, Heather; Inderbitzin, Daniel; Lugli, Alessandro; Zlobec, Inti (2015). TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer. OncoTarget, 6(2), pp. 874-885. Impact Journals LLC 10.18632/oncotarget.2716
Vassella, Erik; Galván Hernández, José Alberto; Zlobec, Inti (2015). Tissue Microarray Technology for Molecular Applications: Investigation of Cross-Contamination between Tissue Samples Obtained from the Same Punching Device. Microarrays, 4(2), pp. 188-195. MDPI 10.3390/microarrays4020188
Dawson, Heather; Grundmann, Sandra; Kölzer, Viktor; Galván Hernández, José Alberto; Kirsch, Richard; Karamitopoulou, Evanthia; Lugli, Alessandro; Inderbitzin, Daniel; Zlobec, Inti (2014). Tyrosine kinase receptor B (TrkB) expression in colorectal cancers highlights anoikis resistance as a survival mechanism of tumour budding cells. Histopathology, 66(5), pp. 715-725. Blackwell Scientific Publications 10.1111/his.12603
Dawson, Heather; Galván Hernández, José Alberto; Helbling, Melina; Müller, Dominique-Elisabeth; Karamitopoulou, Evanthia; Kölzer, Viktor; Economou, Mary; Hammer, Caroline; Lugli, Alessandro; Zlobec, Inti (2014). Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency. International journal of cancer, 134(10), pp. 2342-2351. Wiley-Blackwell 10.1002/ijc.28564
Kölzer, Viktor H.; Lugli, Alessandro; Dawson, Heather; Hädrich, Marion; Berger, Martin D.; Borner, Markus; Mallaev, Makhmudbek; Galván Hernández, José Alberto; Amsler, Jennifer; Schnüriger, Beat; Zlobec, Inti; Inderbitzin, Daniel (2014). CD8/CD45RO T-cell infiltration in endoscopic biopsies of colorectal cancer predicts nodal metastasis and survival. Journal of translational medicine, 12(81), p. 81. BioMed Central 10.1186/1479-5876-12-81
Economou, Mary; Schöni, Liliane; Hammer, Caroline; Galván Hernández, José Alberto; Müller, Dominique-Elisabeth; Zlobec, Inti (2014). Proper paraffin slide storage is crucial for translational research projects involving immunohistochemistry stains. Clinical and translation research, 3(1), p. 4. Springer 10.1186/2001-1326-3-4
