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Egle, Manuel; Mendez-Carmona, Natalia; Segiser, Adrian; Graf, Selianne; Siepe, Matthias; Longnus, Sarah (2024). Hypothermic Oxygenated Perfusion Improves Vascular and Contractile Function by Preserving Endothelial Nitric Oxide Production in Cardiac Grafts Obtained With Donation After Circulatory Death. Journal of the American Heart Association, 13(8), e033503. American Heart Association 10.1161/JAHA.123.033503
Arnold, Maria; Do, Peter; Davidson, Sean M; Large, Stephen R; Helmer, Anja; Beer, Georgia; Siepe, Matthias; Longnus, Sarah L (2024). Metabolic Considerations in Direct Procurement and Perfusion Protocols with DCD Heart Transplantation. International journal of molecular sciences, 25(8) MDPI 10.3390/ijms25084153
Graf, Selianne; Biemmi, Vanessa; Arnold, Maria; Segiser, Adrian; Müller, Anja; Méndez-Carmona, Natalia; Egle, Manuel; Siepe, Matthias; Barile, Lucio; Longnus, Sarah (2024). Macrophage-derived extracellular vesicles alter cardiac recovery and metabolism in a rat heart model of donation after circulatory death. Journal of Cellular and Molecular Medicine, 28(8) Wiley 10.1111/jcmm.18281
Hubacher, Valentin; Egle, Manuel; Graf, Selianne; Arnold, Maria; Segiser, Adrian; Sanz, Maria Nieves; Casoni, Daniela; Garcia Casalta, Luisana; Nettelbeck, Kay; Mihalj, Maks; Siepe, Matthias; Kadner, Alexander; Longnus, Sarah (2024). Open- vs. closed-chest pig models of donation after circulatory death. Frontiers in cardiovascular medicine, 11 Frontiers 10.3389/fcvm.2024.1325160
Louradour, Julien; Ottersberg, Rahel; Segiser, Adrian; Olejnik, Agnieszka; Martinez-Salazar, Berenice; Siegrist, Mark; Egle, Manuel; Barbieri, Miriam; Nimani, Saranda; Alerni, Nicolò; Döring, Yvonne; Odening, Katja E.; Longnus, Sarah (2023). Simultaneous assessment of mechanical and electrical function in Langendorff-perfused ex-vivo mouse hearts. Frontiers in cardiovascular medicine, 10 Frontiers 10.3389/fcvm.2023.1293032
Biemmi, Vanessa; Milano, Giuseppina; Ciullo, Alessandra; Cervio, Elisabetta; Burrello, Jacopo; Dei Cas, Michele; Paroni, Rita; Tallone, Tiziano; Moccetti, Tiziano; Pedrazzini, Giovanni; Longnus, Sarah; Vassalli, Giuseppe; Barile, Lucio (2023). Erratum: Inflammatory extracellular vesicles prompt heart dysfunction via TLR4-dependent NF-κB activation: Erratum. Theranostics, 13(4), p. 1286. Ivyspring International 10.7150/thno.83071
Longnus, Sarah L.; Rutishauser, Nina; Gillespie, Mark N.; Reichlin, Tobias; Carrel, Thierry P.; Sanz, Maria N. (2022). Mitochondrial Damage-associated Molecular Patterns as Potential Biomarkers in DCD Heart Transplantation: Lessons From Myocardial Infarction and Cardiac Arrest. Transplantation direct, 8(1), e1265. Wolters Kluwer Health 10.1097/TXD.0000000000001265
Dejea, Hector; Schlepütz, Christian M.; Méndez-Carmona, Natalia; Arnold, Maria; Garcia-Canadilla, Patricia; Longnus, Sarah L.; Stampanoni, Marco; Bijnens, Bart; Bonnin, Anne (2022). A tomographic microscopy-compatible Langendorff system for the dynamic structural characterization of the cardiac cycle. Frontiers in cardiovascular medicine, 9 Frontiers 10.3389/fcvm.2022.1023483
Méndez Carmona, Natalia; Wyss, Rahel K.; Arnold, Maria; Segiser, Adrian; Kalbermatter, Nina; Joachimbauer, Anna; Carrel, Thierry P.; Longnus, Sarah L. (2021). Effects of graft preservation conditions on coronary endothelium and cardiac functional recovery in a rat model of donation after circulatory death. Journal of heart and lung transplantation, 40(11), pp. 1396-1407. Elsevier 10.1016/j.healun.2021.07.028
Guensch, Dominik P.; Michel, Matthias C.; Huettenmoser, Stefan P; Jung, Bernd; Gulac, Patrik; Segiser, Adrian; Longnus, Sarah L.; Fischer, Kady (2021). The blood oxygen level dependent (BOLD) effect of in-vitro myoglobin and hemoglobin. Scientific reports, 11(1), p. 11464. Springer Nature 10.1038/s41598-021-90908-x
Bona, Martina; Wyss, Rahel K.; Arnold, Maria; Méndez-Carmona, Natalia; Sanz, Maria N.; Günsch, Dominik; Barile, Lucio; Carrel, Thierry P.; Longnus, Sarah L. (2021). Cardiac Graft Assessment in the Era of Machine Perfusion: Current and Future Biomarkers. Journal of the American Heart Association, 10(4), e018966. American Heart Association 10.1161/JAHA.120.018966
Wyss, Rahel K.; Méndez Carmona, Natalia; Arnold, Maria; Segiser, Adrian; Mueller, Matteo; Dutkowski, Philipp; Carrel, Thierry P.; Longnus, Sarah L. (2021). Hypothermic, oxygenated perfusion (HOPE) provides cardioprotection via succinate oxidation prior to normothermic perfusion in a rat model of donation after circulatory death (DCD). American journal of transplantation, 21(3), pp. 1003-1011. Wiley-Blackwell 10.1111/ajt.16258
Arnold, Maria; Méndez-Carmona, Natalia; Wyss, Rahel K.; Joachimbauer, Anna; Casoni, Daniela; Carrel, Thierry; Longnus, Sarah (2021). Comparison of Experimental Rat Models in Donation after Circulatory Death (DCD): in-situ versus ex-situ Ischemia. Frontiers in cardiovascular medicine, 7, p. 596883. Frontiers 10.3389/fcvm.2020.596883
Arnold, Maria; Segiser, Adrian; Graf, Selianne; Méndez-Carmona, Natalia; Sanz, Maria N.; Wyss, Rahel K.; Kalbermatter, Nina; Keller, Nino; Carrel, Thierry; Longnus, Sarah (2021). Pre-ischemic Lactate Levels Affect the Post-ischemic Recovery in an Isolated Rat Heart Model of Donation After Circulatory Death (DCD). Frontiers in cardiovascular medicine, 8 Frontiers 10.3389/fcvm.2021.669205
Gulac, Patrik; Arnold, Maria R.; Grman, Marian; Carrel, Thierry P.; Longnus, Sarah L.; Stankovicova, Tatiana; Tomasova, Lenka (2020). Olanzapine-mediated cardiotoxicity is associated with altered energy metabolism in isolated rat hearts. Acta biochimica Polonica, 67(1), pp. 15-23. Polish Biochemical Society 10.18388/abp.2020_2871
Arnold, Maria; Méndez-Carmona, Natalia; Gulac, Patrik; Wyss, Rahel K; Rutishauser, Nina; Segiser, Adrian; Carrel, Thierry; Longnus, Sarah (2020). Mechanical Postconditioning Promotes Glucose Metabolism and AMPK Activity in Parallel with Improved Post-Ischemic Recovery in an Isolated Rat Heart Model of Donation after Circulatory Death. International journal of molecular sciences, 21(3), p. 964. MDPI 10.3390/ijms21030964
Biemmi, Vanessa; Milano, Giuseppina; Ciullo, Alessandra; Cervio, Elisabetta; Burrello, Jacopo; Dei Cas, Michele; Paroni, Rita; Tallone, Tiziano; Moccetti, Tiziano; Pedrazzini, Giovanni; Longnus, Sarah; Vassalli, Giuseppe; Barile, Lucio (2020). Inflammatory extracellular vesicles prompt heart dysfunction via TRL4-dependent NF-κB activation. Theranostics, 10(6), pp. 2773-2790. Ivyspring International 10.7150/thno.39072
Castellani, Chiara; Burrello, Jacopo; Fedrigo, Marny; Burrello, Alessio; Bolis, Sara; Di Silvestre, Dario; Tona, Francesco; Bottio, Tomaso; Biemmi, Vanessa; Toscano, Giuseppe; Gerosa, Gino; Thiene, Gaetano; Basso, Cristina; Longnus, Sarah L.; Vassalli, Giuseppe; Angelini, Annalisa; Barile, Lucio (2020). Circulating extracellular vesicles as non-invasive biomarker of rejection in heart transplant. Journal of heart and lung transplantation, 39(10), pp. 1136-1148. Elsevier 10.1016/j.healun.2020.06.011
Wyss, Rahel Kathrin; Méndez Carmona, Natalia; Sanz-Garcia, Maria Nieves; Arnold, Maria Regula; Segiser, Adrian; Fiedler, Georg Martin; Carrel, Thierry; Djafarzadeh, Siamak; Tevaearai, Hendrik; Henning Longnus, Sarah (2019). Mitochondrial integrity during early reperfusion in an isolated rat heart model of donation after circulatory death-consequences of ischemic duration. Journal of heart and lung transplantation, 38(6), pp. 647-657. Elsevier 10.1016/j.healun.2018.12.013
Michel, M; Gulac, P; Fischer, Kady; Jung, Bernd; Henning Longnus, Sarah; Günsch, Dominik (June 2019). Effects of myoglobin oxygenation on oxygenation-sensitive cardiovascular magnetic resonance images: an in-vitro study. European heart journal - cardiovascular imaging, 20(Supplement_2). Oxford University Press 10.1093/ehjci/jez111
Sanz-Garcia, Maria Nieves; Farine, Emilie; Niederberger, Petra; Méndez Carmona, Natalia; Wyss, Rahel Kathrin; Arnold, Maria Regula; Gulac, Patrik; Fiedler, Georg M; Gressette, Mélanie; Garnier, Anne; Carrel, Thierry; Tevaearai Stahel, Hendrik T; Henning Longnus, Sarah (2019). Cardioprotective reperfusion strategies differentially affect mitochondria:studies in an isolated rat heart model of donation after circulatory death (DCD). American journal of transplantation, 19(2), pp. 331-344. Wiley-Blackwell 10.1111/ajt.15024
Méndez Carmona, Natalia; Wyss, Rahel K.; Arnold, Maria; Joachimbauer, Anna; Segiser, Adrian; Fiedler, Georg M.; Carrel, Thierry P.; Tevaearai Stahel, Hendrik T.; Longnus, Sarah L. (2019). Differential effects of ischemia/reperfusion on endothelial function and contractility in donation after circulatory death. Journal of heart and lung transplantation, 38(7), pp. 767-777. Elsevier 10.1016/j.healun.2019.03.004
Niederberger, Petra; Farine, Emilie; Raillard, Mathieu Clément; Dornbierer, Monika; Freed, Darren H.; Large, Stephen R.; Chew, Hong C.; MacDonald, Peter S.; Messer, Simon J.; White, Christopher W.; Carrel, Thierry; Tevaearai Stahel, Hendrik T.; Longnus, Sarah L. (2019). Heart Transplantation With Donation After Circulatory Death. Circulation - heart failure, 12(4), pp. 1-14. Lippincott Williams & Wilkins 10.1161/CIRCHEARTFAILURE.118.005517
Jungi, Silvan; Fu, X; Segiser, Adrian; Busch, M; Most, P; Fiedler, Georg Martin; Carrel, Thierry; Tevaearai Stahel, H; Henning Longnus, Sarah; Most, Henriette (2018). Enhanced Cardiac S100A1 Expression Improves Recovery from Global Ischemia-Reperfusion Injury. Journal of cardiovascular translational research JCTR, 11(3), pp. 236-245. Springer 10.1007/s12265-018-9788-y
Farine, Emilie; Egle, Manuel; Boone, Alice C; Christensen, Sandro; Carrel, Thierry; Tevaearai Stahel, Hendrik T; Henning Longnus, Sarah (2018). Development of a cardiac loading device to monitor cardiac function during ex vivo graft perfusion. PLoS ONE, 13(4), e0195721. Public Library of Science 10.1371/journal.pone.0195721
Niederberger, Petra; Farine, Emilie; Arnold, Maria Regula; Wyss, Rahel Kathrin; Sanz-Garcia, Maria Nieves; Méndez Carmona, Natalia; Gahl, Brigitta; Fiedler, Georg Martin; Carrel, Thierry; Tevaearai Stahel, Hendrik T; Henning Longnus, Sarah (2017). High pre-ischemic fatty acid levels decrease cardiac recovery in an isolated rat heart model of donation after circulatory death. Metabolism, 71, pp. 107-117. Elsevier 10.1016/j.metabol.2017.03.007
Stanger, Olaf; Gahl, Brigitta; Grabherr, Michael; Krausler, Richard; Henning Longnus, Sarah; Meinitzer, Andreas; Cadamuro, Janne (2017). Freedom SOLO-Associated Thrombocytopaenia is Valve-Dependent and Not Due to In Vitro Pseudothrombocytopaenia. Heart, lung & circulation, 26(3), pp. 268-275. Elsevier 10.1016/j.hlc.2016.07.002
Stanger, Olaf; Grabherr, Michael; Gahl, Brigitta; Henning Longnus, Sarah; Meinitzer, Andreas; Fiedler, Martin; Tevaearai, Hendrik; Carrel, Thierry (2017). Thrombocytopaenia after aortic valve replacement with stented, stentless and sutureless bioprostheses. European journal of cardio-thoracic surgery, 51(2), pp. 340-346. Oxford University Press 10.1093/ejcts/ezw295
Farine, Emilie; Niederberger, Petra; Wyss, Rahel; Méndez-Carmona, Natalia; Gahl, Brigitta; Fiedler, Martin; Carrel, Thierry; Tevaearai, Hendrik; Henning Longnus, Sarah (2016). Controlled Reperfusion Strategies Improve Cardiac Hemodynamic Recovery after Warm Global Ischemia in an Isolated, Working Rat Heart Model of Donation after Circulatory Death (DCD). Frontiers in psychology, 7 Frontiers Research Foundation 10.3389/fphys.2016.00543
Bartkevics, Maris; Huber, Simon; Mathys, Veronika; Sourdon, Joevin; Dornbierer, Monika; Mendez Carmona, Natalia; Gahl, Brigitta; Carrel, Thierry; Tevaearai, Hendrik; Henning Longnus, Sarah (2016). Efficacy of mechanical postconditioning following warm, global ischaemia depends on circulating fatty acid levels in an isolated, working rat heart model†. European journal of cardio-thoracic surgery, 49(1), pp. 32-39. Oxford University Press 10.1093/ejcts/ezv008
Burn, Felice Antonio (2015). Oxygen-transfer performance of a newly designed, very low-volume membrane oxygenator. (Dissertation, Insel-Gruppe, Medizin)
Burn, Felice; Ciocan, Sorin; Mendez Carmona, Natalia; Berner, Marion; Sourdon, Joevin; Carrel, Thierry; Tevaearai, Hendrik; Henning Longnus, Sarah (2015). Oxygen-transfer performance of a newly designed, very low-volume membrane oxygenator. Interactive cardiovascular and thoracic surgery, 21(3), pp. 352-358. Oxford University Press 10.1093/icvts/ivv141
Huber, S (2015). Efficacy of mechanical postconditioning following warm, global ischaemia depends on circulating fatty acid levels in an isolated, working rat heart model. (Dissertation, Insel-Gruppe, Medizin)
Tevaearai, Hendrik; Zuckermann, Andreas; Carrel, Thierry; Henning Longnus, Sarah (2015). Hearts Not Dead after Circulatory Death. Frontiers in Surgery, 2(46), p. 46. Frontiers 10.3389/fsurg.2015.00046
Tevaearai, Hendrik; Henning Longnus, Sarah; Roland, André; Dick, Florian; Stanger, Olaf; Locca, Didier; Chène, Christiane (2015). Translational Pathway for Drug Development (IV.2). In: Dib, Nabil; Yacoub, Magdi H.; DeMaria, Anthony N.; King, Spencer B. (eds.) Cardiovascular Translational Research. International Society for Cardiovascular Translational Research
Henning Longnus, Sarah; Mendez Carmona, Natalia; Tevaearai, Hendrik (2015). Advances in Hemodynamics Research. In: Keiichi, Itatani (ed.) Advances in Hemodynamics Research. Cardiology Research and Clinical Developments (pp. 249-262). New York, USA: Nova Science Publishers
Chène, Christiane; Henning Longnus, Sarah; Tevaearai, Hendrik (2015). Biomarkers in cardiovascular medicine. In: Dib, Nabil; Yacoub, Magdi H.; DeMaria, Anthony N.; King, Spencer B. (eds.) Cardiovascular Translational Research. International Society for Cardiovascular Translational Research
Longnus, Sarah L.; Mathys, Veronika; Dornbierer, Monika; Dick, Florian; Carrel, Thierry; Tevaearai, Hendrik (2014). Heart transplantation with donation after circulatory determination of death. Nature reviews - cardiology, 11(6), pp. 354-363. Nature Publishing Group 10.1038/nrcardio.2014.45
Brinks, Henriette; Giraud, Marie-Noelle; Segiser, Adrian; Ferrié, Celine; Longnus, Sarah; Ullrich, Nina; Koch, Walter J.; Most, Patrick; Carrel, Thierry; Tevaearai, Hendrik (2014). Dynamic patterns of ventricular remodeling and apoptosis in hearts unloaded by heterotopic transplantation. Journal of heart and lung transplantation, 33(2), pp. 203-210. Elsevier 10.1016/j.healun.2013.10.006
Most, H; Segiser, A; Fu, X; Zuppinger, C; Ullrich, ND; Longnus, SL; Carrel, TP; Tevaearai, HT (2014). P682 Preserved contractile function of unloaded cardiomyocytes despite diminished sarcomere size is associated with troponin I activation. Cardiovascular research, 103(Suppl 1), S124-S125. Oxford University Press 10.1093/cvr/cvu098.106
Stadelmann, Mathieu; Dornbierer, Monika; Clément, David; Gahl, Brigitta; Dick, Florian; Carrel, Thierry P; Tevaearai, Hendrik T; Longnus, Sarah (2013). Mild hypothermia during global cardiac ischemia opens a window of opportunity to develop heart donation after cardiac death. Transplant international, 26(3), pp. 339-48. Oxford: Wiley-Blackwell 10.1111/tri.12022
Sourdon, Joevin; Dornbierer, Monika; Huber, Simon; Gahl, Brigitta; Carrel, Thierry P; Tevaearai, Hendrik T; Longnus, Sarah (2013). Cardiac transplantation with hearts from donors after circulatory declaration of death: haemodynamic and biochemical parameters at procurement predict recovery following cardioplegic storage in a rat model. European journal of cardio-thoracic surgery, 44(1), e87-96. Oxford: Oxford University Press 10.1093/ejcts/ezt142
Berner, Marion; Clément, David; Stadelmann, Mathieu; Kistler, Michael; Boone, Yves; Carrel, Thierry P; Tevaearai, Hendrik T; Longnus, Sarah L (2012). Development of an ultra mini-oxygenator for use in low-volume, buffer-perfused preparations. International journal of artificial organs, 35(4), pp. 308-315. Milano: Wichtig Editore 10.5301/ijao.5000075
Dornbierer, Monika; Stadelmann, Mathieu; Sourdon, Joevin; Gahl, Brigitta; Cook, Stéphane; Carrel, Thierry P; Tevaearai, Hendrik T; Longnus, Sarah L (2012). Early reperfusion hemodynamics predict recovery in rat hearts: a potential approach towards evaluating cardiac grafts from non-heart-beating donors. PLoS ONE, 7(8), e43642. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0043642
Longnus, SL; Berner, M; Stadelmann, M; Kistler, M; Boone, Y; Carrel, TP; Tevaearai, HT (2010). Development of an ultra mini-oxygenator for use in low-volume perfusion circuits. British journal of surgery, 94(S4), I-58. Bristol, UK: John Wright & Sons
Stadelmann, M; Clément, D; Carrel, T; Tevaearai, H; Longnus, S (2010). Prolonged cardiac ischemic tolerance with mild hypothermia. Interactive cardiovascular and thoracic surgery, 11(S63-S126) Oxford: Oxford University Press
Sajan, M P; Bandyopadhyay, G; Miura, A; Standaert, M L; Nimal, S; Longnus, S L; Van Obberghen, E; Hainault, I; Foufelle, F; Kahn, R; Braun, U; Leitges, M; Farese, R V (2010). AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC. American journal of physiology - endocrinology and metabolism, 298(2), E179-92. Bethesda, Md.: American Physiological Society 10.1152/ajpendo.00392.2009
