Nakas, Christos T.

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Banholzer, Nicolas; Herzig, David; Piazza, Camillo; Álvarez-Martínez, Mario; Nakas, Christos T; Kosinski, Christophe; Feuerriegel, Stefan; Hovorka, Roman; Bally, Lia (2021). Effect of nutrition on postprandial glucose control in hospitalized patients with type 2 diabetes receiving fully automated closed-loop insulin therapy. Diabetes, obesity & metabolism, 23(1), pp. 234-239. Wiley 10.1111/dom.14187

Herzig, David; Studer, David; Nakas, Christos T; Kuenzli, Christina; Stauffer, Thomas P; Hovorka, Roman; Bally, Lia (2021). Effect of fully automated closed-loop insulin delivery using faster aspart versus standard aspart on gluco-regulatory hormones in type 2 diabetes. Diabetes, obesity & metabolism, 23(1), pp. 228-233. Wiley 10.1111/dom.14185


Meier, C; Freiburghaus, K; Bovet, C; Schniering, J; Allanore, Y; Distler, O; Nakas, C; Maurer, B (2020). Serum metabolites as biomarkers in systemic sclerosis-associated interstitial lung disease. Scientific reports, 10(1), p. 21912. Springer Nature 10.1038/s41598-020-78951-6

Reverter-Branchat, Gemma; Groessl, Michael; Nakas, Christos T; Prost, Jean-Christophe; Antwi, Kwasi; Niederkofler, Eric E; Bally, Lia (2020). Rapid quantification of insulin degludec by immunopurification combined with liquid chromatography high-resolution mass spectrometry. Analytical and bioanalytical chemistry, 412(30), pp. 8351-8359. Springer 10.1007/s00216-020-02971-4

Franco-Pereira, A M; Nakas, C T; Athanassiou, C G; Pardo, M C (2020). Testing against umbrella or tree orderings for binomial proportions with an adaptation of an insect resistance case. Biometrical journal, 62(6), pp. 1574-1588. Wiley-VCH 10.1002/bimj.201900272

McCarthy, Olivia; Pitt, Jason; Churm, Rachel; Dunseath, Gareth J; Jones, Charlotte; Bally, Lia; Nakas, Christos T; Deere, Rachel; Eckstein, Max L; Bain, Stephen C; Moser, Othmar; Bracken, Richard M (2020). Metabolomic, hormonal and physiological responses to hypoglycemia versus euglycemia during exercise in adults with type 1 diabetes. BMJ open diabetes research & care, 8(1) BMJ Publishing Group 10.1136/bmjdrc-2020-001577

Tripyla, Afroditi; Herzig, David; Dehais, Joachim; Nakas, Christos T.; Amiet, Franziska; Andreou, Andreas; Gloor, Beat; Vogt, Andreas; Bally, Lia (2020). Performance of a factory‐calibrated, real‐time continuous glucose monitoring system during elective abdominal surgery. Diabetes, obesity & metabolism, 22(9), pp. 1678-1682. Wiley 10.1111/dom.14073

Herzig, David; Dehais, Joachim; Prost, Jean-Christophe; Nakas, Christos T.; Stettler, Christoph; Bally, Lia; Hovorka, Roman (2020). Pharmacokinetics of Faster and Standard Insulin Aspart During Fully Closed-Loop Insulin Delivery in Type 2 Diabetes. Diabetes technology & therapeutics, 22(9), pp. 691-696. Mary Ann Liebert 10.1089/dia.2019.0477

Kosinski, Christophe; Herzig, David; Laesser, Céline Isabelle; Nakas, Christos T.; Melmer, Andreas; Vogt, Andreas; Vogt, Bruno; Laimer, Markus; Bally, Lia; Stettler, Christoph (2020). A Single Load of Fructose Attenuates the Risk of Exercise-Induced Hypoglycemia in Adults With Type 1 Diabetes on Ultra-Long-Acting Basal Insulin: A Randomized, Open-Label, Crossover Proof-of-Principle Study. Diabetes care, 43(9), pp. 2010-2016. American Diabetes Association 10.2337/dc19-2250

Freiburghaus, Katrin; Leichtle, Alexander Benedikt; Nakas, Christos T.; Fiedler, Georg M.; Largiadèr, Carlo R. (2020). Effects of Freezing and Thawing Procedures on Selected Clinical Chemistry Parameters in Plasma. Biopreservation and biobanking, 18(4), pp. 297-304. Liebert 10.1089/bio.2020.0005

Arnold, Markus; Nakas, Christos; Luft, Andreas; Christ-Crain, Mirjam; Leichtle, Alexander; Katan, Mira (2020). Independent Prognostic Value of MRproANP (Midregional Proatrial Natriuretic Peptide) Levels in Patients With Stroke Is Unaltered Over Time. Stroke, 51(6), pp. 1873-1875. American Heart Association 10.1161/STROKEAHA.120.029333

Musy, Sarah N; Endrich, Olga; Leichtle, Alexander B; Griffiths, Peter; Nakas, Christos T; Simon, Michael (2020). Longitudinal Study of the Variation in Patient Turnover and Patient-to-Nurse Ratio: Descriptive Analysis of a Swiss University Hospital. Journal of medical internet research, 22(4), e15554. JMIR Publications 10.2196/15554

Endrich, Olga; Triep, Karen; Torbica, Nenad; Nakas, Christos T.; Nelle, Mathias; Fiedler, Georg; Raio, Luigi (2020). Changepoint analysis of gestational age and birth weight: proposing a refinement of Diagnosis Related Groups. Pediatric research, 87(5), pp. 910-916. Springer Nature 10.1038/s41390-019-0669-0

Herzig, David; Nakas, Christos T; Stalder, Janine; Kosinski, Christophe; Laesser, Céline; Dehais, Joachim; Jäggi, Raphael; Leichtle, Alexander Benedikt; Dahlweid, Fried-Michael; Stettler, Christoph; Bally, Lia (2020). Volumetric Food Quantification Using Computer Vision on a Depth-Sensing Smartphone: Preclinical Study. JMIR mHealth and uHealth, 8(3), e15294. JMIR Publications 10.2196/15294

Alonso, Rosa; Nakas, Christos T.; Carmen Pardo, M. (2020). A study of indices useful for the assessment of diagnostic markers in non-parametric ROC curve analysis. Communications in statistics. Simulation and computation, 49(8), pp. 2102-2113. Taylor & Francis 10.1080/03610918.2018.1511806

Franco-Pereira, Alba M.; Nakas, Christos T.; Pardo, M. Carmen (2020). Biomarker assessment in ROC curve analysis using the length of the curve as an index of diagnostic accuracy: the binormal model framework. AStA Advances in statistical analysis, 104(4), pp. 625-647. Springer 10.1007/s10182-020-00371-8


Franco-Pereira, Alba M; Nakas, Christos T.; Leichtle, Alexander Benedikt; Pardo, M Carmen (2019). Bootstrap-based testing approaches for the assessment of the diagnostic accuracy of biomarkers subject to a limit of detection. Statistical Methods in Medical Research, 28(5), pp. 1564-1578. SAGE Publications (UK and US) 10.1177/0962280218769334

Bantis, Leonidas E; Nakas, Christos T.; Reiser, Benjamin (2019). Construction of confidence intervals for the maximum of the Youden index and the corresponding cutoff point of a continuous biomarker. Biometrical journal, 61(1), pp. 138-156. Wiley-VCH 10.1002/bimj.201700107

Noll, Samuel; Furrer, Reinhard; Reiser, Benjamin; Nakas, Christos T. (2019). Inference in receiver operating characteristic surface analysis via a trinormal model‐based testing approach. Stat, 8(1) Wiley 10.1002/sta4.249


von Wolff, M.; Nakas, Christos T.; Wolf, Marlene; Merz, Tobias; Hilty, M P; Veldhuis, J D; Huber, A R; Pichler Hefti, Jacqueline Renée (2018). Adrenal, thyroid and gonadal axes are affected at high altitude. Endocrine Connections, 7(10), pp. 1081-1089. BioScientifica 10.1530/EC-18-0242

Nakas, Christos T.; Reiser, Benjamin (2018). Editorial for the special issue of "Statistical Methods in Medical Research" on "Advanced ROC analysis". Statistical Methods in Medical Research, 27(3), pp. 649-650. SAGE Publications (UK and US) 10.1177/0962280217742536

Blissenbach, Birgit; Nakas, Christos T.; Krönke, Martin; Geiser, Thomas; Merz, Tobias; Pichler Hefti, Jacqueline Renée (2018). Hypoxia-induced changes in plasma microRNAs correlate with pulmonary artery pressure at high altitude. American journal of physiology - lung cellular and molecular physiology, 314(1), L157-L164. American Physiological Society 10.1152/ajplung.00146.2017

Lesche, Dorothea; Sigurdardottir, Vilborg; Leichtle, Alexander Benedikt; Nakas, Christos T.; Christians, Uwe; Englberger, Lars; Fiedler, Georg Martin; Largiadèr, Carlo Rodolfo; Mohacsi, Paul; Sistonen, Johanna (2018). Targeted and global pharmacometabolomics in everolimus-based immunosuppression: association of co-medication and lysophosphatidylcholines with dose requirement. Metabolomics, 14(1), p. 3. Springer 10.1007/s11306-017-1294-8

Liu, Xinyu; Hoene, Miriam; Yin, Peiyuan; Fritsche, Louise; Plomgaard, Peter; Hansen, Jakob S.; Nakas, Christos T.; Niess, Andreas M.; Hudemann, Jens; Haap, Michael; Mendy, Maimuna; Weigert, Cora; Wang, Xiaolin; Fritsche, Andreas; Peter, Andreas; Häring, Hans-Ulrich; Xu, Guowang; Lehmann, Rainer (2018). Quality Control of Serum and Plasma by Quantification of (4E,14Z)-Sphingadienine-C18-1-Phosphate Uncovers Common Preanalytical Errors During Handling of Whole Blood. Clinical chemistry, 64(5), pp. 810-819. American Association for Clinical Chemistry 10.1373/clinchem.2017.277905


Haider, Dominik; Klemenz, Thomas; Fiedler, Georg Martin; Nakas, Christos T.; Exadaktylos, Aristomenis; Leichtle, Alexander Benedikt (2017). In response to the letter to the editor on our manuscript "High sensitive cardiac troponin T: Testing the test" by Dr. Badertscher. International journal of cardiology, 234, p. 127. Elsevier 10.1016/j.ijcard.2017.01.114

Haider, Dominik; Klemenz, Thomas; Fiedler, Martin; Nakas, Christos T.; Exadaktylos, Aristomenis; Leichtle, Alexander Benedikt (2017). High sensitive cardiac troponin T: Testing the test. International journal of cardiology, 228, pp. 779-783. Elsevier 10.1016/j.ijcard.2016.10.043

Yin, Jingjing; Nakas, Christos T.; Tian, Lili; Reiser, Benjamin (2017). Confidence intervals for differences between volumes under receiver operating characteristic surfaces (VUS) and generalized Youden indices (GYIs). Statistical Methods in Medical Research, 27(3), pp. 675-688. SAGE Publications (UK and US) 10.1177/0962280217740787

Bally, Lia; Bovet, Cédric; Nakas, Christos T.; Zueger, Thomas; Prost, Jean-Christophe; Nuoffer, Jean-Marc; Leichtle, Alexander Benedikt; Fiedler, Georg Martin; Stettler, Christoph (2017). A metabolomics approach to uncover effects of different exercise modalities in type 1 diabetes. Metabolomics, 13(7) Springer 10.1007/s11306-017-1217-8


Bally, Lia; Dehais, Joachim Blaise; Nakas, Christos T.; Anthimopoulos, Marios; Laimer, Markus; Rhyner, Daniel Kaspar; Rosenberg, George; Züger, Thomas; Diem, Peter; Mougiakakou, Stavroula; Stettler, Christoph (2016). Carbohydrate Estimation Supported by the GoCARB system in Individuals With Type 1 Diabetes: A Randomized Prospective Pilot Study. Diabetes care, 40(2), dc162173. American Diabetes Association 10.2337/dc16-2173

Gerofotis, Christos D; Ioannou, Charalampos S; Nakas, Christos T.; Papadopoulos, Nikos T (2016). The odor of a plant metabolite affects life history traits in dietary restricted adult olive flies. Scientific Reports, 6, p. 28540. Nature Publishing Group 10.1038/srep28540

Reiser, Benjamin; Nakas, Christos T. (2016). On 'Efficient statistical tests to compare Youden index: accounting for contingency correlation'. Statistics in medicine, 35(4), pp. 635-636. Wiley-Blackwell 10.1002/sim.6574

Lesche, Dorothea; Geyer, Roland; Lienhard, Daniel; Nakas, Christos T.; Diserens, Gaëlle; Vermathen, Peter; Leichtle, Alexander Benedikt (2016). Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome. Metabolomics, 12(10), p. 159. Springer 10.1007/s11306-016-1109-3

Nakas, Christos T.; Schütz, Narayan; Werners, Marcus; Leichtle, Alexander Benedikt (2016). Accuracy and Calibration of Computational Approaches for Inpatient Mortality Predictive Modeling. PLoS ONE, 11(7), e0159046. Public Library of Science 10.1371/journal.pone.0159046

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