Takala, Jukka

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Wiest, Reiner; Niess, Jan Hendrik; Rothen, Hans Ulrich; Merz, Tobias Michael; Takala, Jukka; Malinka, Thomas; Seiler, Christian A. (October 2015). Non-CO2-insufflation and acute abdominal compartment during emergency endoscopy contributing to fatal outcome in advanced obstructive tumor of the gastro-esophageal junction with severe bleeding (Unpublished). In: SGG annual congress. Interlaken. 01.-02.10.2015.

Krejci, Vladimir; Hiltebrand, Luzius B; Jakob, Stephan M; Takala, Jukka; Sigurdsson, Gisli H (2007). Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow. Critical care, 11(6), R129. London: BioMed Central 10.1186/cc6197

Albert, Richard K; Slutsky, Arthur S; Ranieri, Marco; Takala, Jukka; Torres, Antoni (eds.) (2006). Clinical Critical Care Medicine. Philadelphia: Mosby

Yes

Bachmann, Kaspar F; Haenggi, Matthias; Jakob, Stephan M; Takala, Jukka; Gattinoni, Luciano; Berger, David (2024). Comment on: "A novel 'shunt fraction' method to derive native cardiac output during liberation from central VA ECMO" by Lim, HS. ESC Heart Failure, 11(4), pp. 2464-2466. Wiley 10.1002/ehf2.14804

Moser, André; Raj, Rahul; Reinikainen, Matti; Jakob, Stephan M; Takala, Jukka (2024). Effect of mortality prediction models on resource use benchmarking of intensive care units. Journal of critical care, 82(154814), p. 154814. Elsevier 10.1016/j.jcrc.2024.154814

Pölkki, Anssi; Moser, André; Raj, Rahul; Takala, Jukka; Bendel, Stepani; Jakob, Stephan M; Reinikainen, Matti (2024). The authors reply. Critical care medicine, 52(4), e217-e218. Wolters Kluwer Health 10.1097/CCM.0000000000006205

Pölkki, Anssi; Moser, André; Raj, Rahul; Takala, Jukka; Bendel, Stepani; Jakob, Stephan M; Reinikainen, Matti (2024). The Influence of Potential Organ Donors on Standardized Mortality Ratios and ICU Benchmarking. Critical care medicine, 52(3), pp. 387-395. Lippincott Williams & Wilkins 10.1097/CCM.0000000000006098

Raj, Rahul; Moser, André; Starkopf, Joel; Reinikainen, Matti; Varpula, Tero; Jakob, Stephan M; Takala, Jukka (2024). Variation in Severity-Adjusted Resource use and Outcome for Neurosurgical Emergencies in the Intensive Care Unit. Neurocritical care, 40(1), pp. 251-261. Springer 10.1007/s12028-023-01723-3

Shehabi, Yahya; Serpa Neto, Ary; Bellomo, Rinaldo; Howe, Belinda D; Arabi, Yaseen M; Bailey, Michael; Bass, Frances E; Bin Kadiman, Suhaini; McArthur, Colin J; Reade, Michael C; Seppelt, Ian M; Takala, Jukka; Wise, Matt P; Webb, Steve A (2023). Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III). American journal of respiratory and critical care medicine, 207(7), pp. 876-886. American Thoracic Society 10.1164/rccm.202206-1208OC

Parker, Margaret M; Pinsky, Michael R; Takala, Jukka; Vincent, Jean-Louis (2023). The Story of the Pulmonary Artery Catheter: Five Decades in Critical Care Medicine. Critical care medicine, 51(2), pp. 159-163. Lippincott Williams & Wilkins 10.1097/CCM.0000000000005718

Moreno, Rui; Rhodes, Andrew; Piquilloud, Lise; Hernandez, Glenn; Takala, Jukka; Gershengorn, Hayley B; Tavares, Miguel; Coopersmith, Craig M; Myatra, Sheila N; Singer, Mervyn; Rezende, Ederlon; Prescott, Hallie C; Soares, Márcio; Timsit, Jean-François; de Lange, Dylan W; Jung, Christian; De Waele, Jan J; Martin, Greg S; Summers, Charlotte; Azoulay, Elie; ... (2023). The Sequential Organ Failure Assessment (SOFA) Score: has the time come for an update? Critical care, 27(1), p. 15. BioMed Central 10.1186/s13054-022-04290-9

Takala, Jukka; Moser, André; Reinikainen, Matti; Varpula, Tero; Raj, Rahul; Jakob, Stephan M (2022). Impact of cardiac surgery and neurosurgery patients on variation in severity-adjusted resource use in intensive care units. Journal of critical care, 71, p. 154110. Elsevier 10.1016/j.jcrc.2022.154110

Pölkki, Anssi; Pekkarinen, Pirkka T; Takala, Jukka; Selander, Tuomas; Reinikainen, Matti (2022). Association of Sequential Organ Failure Assessment (SOFA) components with mortality. Acta anaesthesiologica Scandinavica, 66(6), pp. 731-741. Wiley 10.1111/aas.14067

Werner-Moller, Per; Heinisch, Paul Philipp; Hana, Anisa; Bachmann, Kaspar F; Sondergaard, Soren; Jakob, Stephan M; Takala, Jukka; Berger, David (2022). Experimental validation of a mean systemic pressure analog against zero-flow measurements in porcine VA-ECMO. Journal of applied physiology, 132(3), pp. 726-736. American Physiological Society 10.1152/japplphysiol.00804.2021

Takala, Jukka; Moser, André; Raj, Rahul; Pettilä, Ville; Irincheeva, Irina; Selander, Tuomas; Kiiski, Olli; Varpula, Tero; Reinikainen, Matti; Jakob, Stephan M. (2022). Variation in severity-adjusted resource use and outcome in intensive care units. Intensive care medicine, 48(1), pp. 67-77. Springer-Verlag 10.1007/s00134-021-06546-4

Fung, Christian; Z'Graggen, Werner J.; Jakob, Stephan M.; Gralla, Jan; Haenggi, Matthias; Rothen, Hans-Ulrich; Mordasini, Pasquale; Lensch, Michael; Söll, Nicole; Terpolilli, Nicole; Feiler, Sergej; Oertel, Markus F.; Raabe, Andreas; Plesnila, Nikolaus; Takala, Jukka; Beck, Jürgen (2022). Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Delayed Cerebral Ischemia. Frontiers in neurology, 13, p. 817072. Frontiers Media S.A. 10.3389/fneur.2022.817072

Vincent, Jean-Louis; Singer, Mervyn; Einav, Sharon; Moreno, Rui; Wendon, Julia; Teboul, Jean-Louis; Bakker, Jan; Hernandez, Glenn; Annane, Djillali; de Man, Angélique M E; Monnet, Xavier; Ranieri, V Marco; Hamzaoui, Olfa; Takala, Jukka; Juffermans, Nicole; Chiche, Jean-Daniel; Myatra, Sheila N; De Backer, Daniel (2021). Equilibrating SSC guidelines with individualized care. Critical care, 25(1), p. 397. BioMed Central 10.1186/s13054-021-03813-0

Cioccari, Luca; Jakob, Stephan M.; Takala, Jukka (2021). Should Vasopressors Be Started Early in Septic Shock? Seminars in respiratory and critical care medicine, 42(5), pp. 683-688. Thieme 10.1055/s-0041-1733897

Valenti, Elisa; Moller, Per W; Takala, Jukka; Berger, David (2021). Collapsibility of caval vessels and right ventricular afterload: decoupling of stroke volume variation from preload during mechanical ventilation. Journal of applied physiology, 130(5), pp. 1562-1572. American Physiological Society 10.1152/japplphysiol.01039.2020

Shehabi, Yahya; Serpa Neto, Ary; Howe, Belinda D; Bellomo, Rinaldo; Arabi, Yaseen M; Bailey, Michael; Bass, Frances E; Kadiman, Suhaini Bin; McArthur, Colin J; Reade, Michael C; Seppelt, Ian M; Takala, Jukka; Wise, Matt P; Webb, Steve A (2021). Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial. Intensive care medicine, 47(4), pp. 455-466. Springer-Verlag 10.1007/s00134-021-06356-8

Corrêa, Thiago Domingos; Pereira, Adriano José; Takala, Jukka; Jakob, Stephan Mathias (2020). Regional venous-arterial CO2 to arterial-venous O2 content difference ratio in experimental circulatory shock and hypoxia. Intensive care medicine experimental, 8(1), p. 64. Springer 10.1186/s40635-020-00353-9

Berger, David; Hobi, Jan; Möller, Per W.; Haenggi, Matthias; Takala, Jukka; Jakob, Stephan M. (2020). Right ventricular stroke volume assessed by pulmonary artery pulse contour analysis. Intensive care medicine experimental, 8(1), p. 58. Springer 10.1186/s40635-020-00347-7

Liu, Shengchen; do Amaral Campos, Pedro Paulo Zanella; Casoni, Daniela; Berger, David; Kohler, Andreas; Bloch, Andreas; Bervini, David; Setzer, Florian; Cameron, David R.; Z'Graggen, Werner; Hana, Anisa; Langer, Rupert; Corrêa, Thiago D.; Beldi, Guido; Takala, Jukka; Jakob, Stephan M. (2020). Defense mechanisms to increasing back pressure for hepatic oxygen transport and venous return in porcine fecal peritonitis. American journal of physiology - gastrointestinal and liver physiology, 319(3), G289-G302. American Physiological Society 10.1152/ajpgi.00216.2020

Cioccari, Luca; Luethi, Nora; Bailey, Michael; Shehabi, Yahya; Howe, Belinda; Messmer, Anna S.; Proimos, Helena K.; Peck, Leah; Young, Helen; Eastwood, Glenn M.; Merz, Tobias M.; Takala, Jukka; Jakob, Stephan M.; Bellomo, Rinaldo (2020). The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial. Critical care, 24(1), p. 441. BioMed Central 10.1186/s13054-020-03115-x

Bachmann, Kaspar Felix; Haenggi, Matthias; Jakob, Stephan M.; Takala, Jukka; Gattinoni, Luciano; Berger, David (2020). Gas exchange calculation may estimate changes in pulmonary blood flow during veno-arterial extracorporeal membrane oxygenation in a porcine model. American journal of physiology - lung cellular and molecular physiology, 318(6), L1211-L1221. American Physiological Society 10.1152/ajplung.00167.2019

Liu, Shengchen; Moller, Per W.; Kohler, Andreas; Hana, Anisa; Beldi, Guido; Obrist, Dominik; Berger, David; Takala, Jukka; Jakob, Stephan M. (2020). Effects of Trendelenburg position and increased airway pressure on hepatic regional blood flow of normal and resected liver. Journal of applied physiology, 128(3), pp. 667-680. American Physiological Society 10.1152/japplphysiol.00705.2019

Werner-Moller, Per; Berger, David; Takala, Jukka (2020). Letter to the Editor: Venous return and the physical connection between distribution of segmental pressures and volumes. American journal of physiology - heart and circulatory physiology, 318(1), H203-H204. American Physiological Society 10.1152/ajpheart.00698.2019

Wernerman, Jan; Christopher, Kenneth B; Annane, Djillali; Casaer, Michael P; Coopersmith, Craig M; Deane, Adam M; De Waele, Elisabeth; Elke, Gunnar; Ichai, Carole; Karvellas, Constantine J; McClave, Stephen A; Oudemans-van Straaten, Heleen M; Rooyackers, Olav; Stapleton, Renee D; Takala, Jukka; van Zanten, Arthur R H; Wischmeyer, Paul E; Preiser, Jean-Charles; Vincent, Jean-Louis (2019). Metabolic support in the critically ill: a consensus of 19. Critical care, 23(1), p. 318. BioMed Central 10.1186/s13054-019-2597-0

Merz, Tobias; Cioccari, Luca; Frey, Pascal Marcel; Bloch, Andreas; Berger, David; Zante, Björn; Jakob, Stephan; Takala, Jukka (2019). Correction to: Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial. Intensive care medicine, 45(9), p. 1330. Springer-Verlag 10.1007/s00134-019-05700-3

Merz, Tobias; Cioccari, Luca; Frey, Pascal Marcel; Bloch, Andreas; Berger, David; Zante, Björn; Jakob, Stephan; Takala, Jukka (2019). Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial. Intensive care medicine, 45(8), pp. 1093-1102. Springer-Verlag 10.1007/s00134-019-05670-6

Shehabi, Yahya; Howe, Belinda D; Bellomo, Rinaldo; Arabi, Yaseen M; Bailey, Michael; Bass, Frances E; Bin Kadiman, Suhaini; McArthur, Colin J; Murray, Lynnette; Reade, Michael C; Seppelt, Ian M; Takala, Jukka; Wise, Matt P; Webb, Steven A (2019). Early Sedation with Dexmedetomidine in Critically Ill Patients. The New England journal of medicine, 380(26), pp. 2506-2517. Massachusetts Medical Society 10.1056/NEJMoa1904710

Werner Möller, Per; Sondergaard, Soren; Jakob, Stephan; Takala, Jukka; Berger, David (2019). Effect of volume status on the estimation of mean systemic filling pressure. Journal of applied physiology, 126(6), pp. 1503-1513. American Physiological Society 10.1152/japplphysiol.00897.2018

Pfortmueller, Carmen A.; Faeh, Livia; Müller, Martin; Eberle, Balthasar; Jenni, Hansjörg; Zante, Björn; Prazak, Josef; Englberger, Lars; Takala, Jukka; Jakob, Stephan M. (2019). Fluid management in patients undergoing cardiac surgery: effects of an acetate- versus lactate-buffered balanced infusion solution on hemodynamic stability (HEMACETAT). Critical care, 23(1), p. 159. BioMed Central 10.1186/s13054-019-2423-8

Werner Möller, Per; Hana, Anisa; Heinisch, Paul Philipp; Liu, Shengchen; Djafarzadeh, Siamak; Hänggi, Matthias; Bloch, Andreas; Takala, Jukka; Jakob, Stephan; Berger, David (2019). The Effects of Vasoconstriction and Volume Expansion on Veno-Arterial ECMO Flow. Shock, 51(5), pp. 650-658. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001197

Schefold, Joerg C.; Messmer, Anna S.; Wenger, Stefanie; Müller, Lionel; von Haehling, Stephan; Doehner, Wolfram; McPhee, Jamie S; Fux, Michaela; Rösler, Kai M; Scheidegger, Olivier; Olariu, Radu; Z'Graggen, Werner; Rezzi, Serge; Grathwohl, Dominik; Konz, Tobias; Takala, Jukka; Cuenoud, Bernard; Jakob, Stephan M. (2019). Nutrient pattern analysis in critically ill patients using Omics technology (NAChO) - Study protocol for a prospective observational study. Medicine, 98(1), e13937. Lippincott Williams & Wilkins 10.1097/MD.0000000000013937

Berger, David; Werner Möller, Per; Takala, Jukka (2019). Reply to “Is the Guytonian framework justified in explaining heart lung interactions?” and “Venous return, mean systemic pressure and getting the right answer for the wrong reason”. Annals of translational medicine, 7(8), p. 186. AME Publishing Company 10.21037/atm.2019.04.50

Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; Wise, Matt P; Schefold, Joerg C.; Keus, Frederik; Guttormsen, Anne B; Bendel, Stepani; Borthwick, Mark; Lange, Theis; Rasmussen, Bodil S; Siegemund, Martin; Bundgaard, Helle; Elkmann, Thomas; Jensen, Jacob V; Nielsen, Rune D; Liboriussen, Lisbeth; Bestle, Morten H; Elkjær, Jeanie M; ... (2018). Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU. The New England journal of medicine, 379(23), pp. 2199-2208. Massachusetts Medical Society 10.1056/NEJMoa1714919

Gorrasi, José Antonio; Jakob, Stephan; Tovar, Luis Antonio; Balsiger, Bruno Markus; Brandt, Sebastian; Brügger, Lukas; Bracht, Hendrik; Takala, Jukka (2018). Perioperative Fluid Accumulation Impairs Intestinal Contractility to a Smilar Extent as Peritonitis and Endotoxemia. Shock, 50(6), pp. 735-740. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001088

Cioccari, Luca; Zante, Bjoern; Bloch, Andreas; Berger, David; Limacher, Andreas; Jakob, Stephan M; Takala, Jukka; Merz, Tobias M (2018). Correction to: Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. [correction]. Trials, 19(1), p. 587. BioMed Central 10.1186/s13063-018-3001-0

Cioccari, Luca; Zante, Bjoern; Bloch, Andreas; Berger, David; Limacher, Andreas; Jakob, Stephan M; Takala, Jukka; Merz, Tobias M (2018). Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. Trials, 19(1), p. 362. BioMed Central 10.1186/s13063-018-2714-4

Schefold, Joerg C.; Zürcher, Patrick; Takala, Jukka (2018). The authors reply. Critical care medicine, 46(7), e727-e728. Lippincott Williams & Wilkins 10.1097/CCM.0000000000003163

Aneman, Anders; Brechot, Nicholas; Brodie, Daniel; Colreavy, Frances; Fraser, John; Gomersall, Charles; McCanny, Peter; Moller-Sorensen, Peter Hasse; Takala, Jukka; Valchanov, Kamen; Vallely, Michael (2018). Advances in critical care management of patients undergoing cardiac surgery. Intensive care medicine, 44(6), pp. 799-810. Springer-Verlag 10.1007/s00134-018-5182-0

Zürcher, Patrick; Takala, Jukka; Schefold, Joerg C. (2018). The authors reply. Critical care medicine, 46(4), e344-e345. Lippincott Williams & Wilkins 10.1097/CCM.0000000000002978

Sommerstein, Rami; Merz, Tobias; Jakob, Stephan; Takala, Jukka; Marschall, Jonas (2018). Decontamination of Extracorporeal Membrane Oxygenator Devices With an Intensified Disinfection Protocol: How Strict Is Too Strict? Infection control and hospital epidemiology, 39(3), pp. 366-367. Cambridge University Press 10.1017/ice.2017.283

Glas, Michael; Frick, Tamara; Springe, Dirk; Putzu, Alessandro; Zürcher, Patrick; Grandgirard, Denis; Leib, Stephen; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2018). Neuroprotection with the P53-Inhibitor Pifithrin-μ After Cardiac Arrest in a Rodent Model. Shock, 49(2), pp. 229-234. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000917

Berger, David; Takala, Jukka (2018). Determinants of systemic venous return and the impact of positive pressure ventilation. Annals of translational medicine, 6(18), p. 350. AME Publishing Company 10.21037/atm.2018.05.27

Eggmann, Sabrina; Verra, Martin L.; Luder, Gere; Takala, Jukka; Jakob, Stephan (2018). Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: A randomised controlled trial. PLoS ONE, 13(11), e0207428. Public Library of Science 10.1371/journal.pone.0207428

Schefold, Joerg C.; Berger, David; Zürcher, Patrick; Lensch, Michael; Perren, Andrea; Jakob, Stephan; Parviainen, Ilkka; Takala, Jukka (2017). Dysphagia in Mechanically Ventilated ICU Patients (DYnAMICS): A Prospective Observational Trial. Critical care medicine, 45(12), pp. 2061-2069. Lippincott Williams & Wilkins 10.1097/CCM.0000000000002765

Shehabi, Yahya; Forbes, Andrew B; Arabi, Yaseen; Bass, Frances; Bellomo, Rinaldo; Kadiman, Suhaini; Howe, Belinda D; McArthur, Colin; Reade, Michael C; Seppelt, Ian; Takala, Jukka; Webb, Steve; Wise, Matthew P (2017). The SPICE III study protocol and analysis plan: a randomised trial of early goaldirected sedation compared with standard care in mechanically ventilated patients. Critical care and resuscitation, 19(4), pp. 318-326. College of Intensive Care Medicine of Australia and New Zealand

Jakob, Stephan; Takala, Jukka (2017). Subcellular Energetics and Metabolism: A Cross-Species Framework. Anesthesia and analgesia, 125(6), p. 2160. Lippincott Williams & Wilkins 10.1213/ANE.0000000000002476

Werner Möller, Per; Winkler, Berhard; Hurni, Samuel; Heinisch, Paul Philipp; Bloch, Andreas; Sondergaard, Soren; Jakob, Stephan; Takala, Jukka; Berger, David (2017). Right atrial pressure and venous return during cardiopulmonary bypass. American journal of physiology - heart and circulatory physiology, 313(2), H408-H420. American Physiological Society 10.1152/ajpheart.00081.2017

Bloch, Andreas; Kohler, Andreas; Posthaus, Horst; Berger, David; Santos, Laura; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2017). Gastrointestinal Impedance Spectroscopy to Detect Hypoperfusion During Hemorrhage. Shock, 48(2), pp. 185-195. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000824

Jakob, Stephan M; Bütikofer, Lukas; Berger, David; Coslovsky, Michael; Takala, Jukka (2017). A randomized controlled pilot study to evaluate the effect of an enteral formulation designed to improve gastrointestinal tolerance in the critically ill patient-the SPIRIT trial. Critical care, 21(1), p. 140. BioMed Central 10.1186/s13054-017-1730-1

De Marchis, Gian Marco; Schaad, Chris; Fung, Christian; Beck, Jürgen; Gralla, Jan; Takala, Jukka; Jakob, Stephan (2017). Gender-related differences in aneurysmal subarachnoid hemorrhage: A hospital based study. Clinical neurology and neurosurgery, 157, pp. 82-87. Elsevier 10.1016/j.clineuro.2017.04.009

Corrêa, Thiago Domingos; Pereira, Adriano José; Brandt, Sebastian; Vuda, Madhusudanarao; Djafarzadeh, Siamak; Takala, Jukka; Jakob, Stephan (2017). Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis. Critical care, 21(1), p. 105. BioMed Central 10.1186/s13054-017-1691-4

Jakob, Stephan; Takala, Jukka (2017). Comments on Teboul and Scheeren: understanding the Haldane effect. Intensive care medicine, 43(4), p. 597. Springer 10.1007/s00134-017-4697-0

Berger, David; Werner Möller, Per; Blöchlinger, Stefan; Bloch, Andreas; Jakob, Stephan; Takala, Jukka (21 March 2017). P106 Methodological issues for the determination of mean systemic filling pressure at the end of life. Critical care, 21(Suppl1), p. 41. BioMed Central

Werner Möller, Per; Jakob, Stephan; Takala, Jukka; Berger, David (21 March 2017). P108 Right atrial pressure as back-pressure to venous return. Critical care, 21(Suppl 1), pp. 41-42. BioMed Central

Varis, Elina; Pettilä, Ville Yrjö Olavi; Poukkanen, Meri; Jakob, Stephan; Karlsson, Sari; Perner, Anders; Takala, Jukka; Wilkman, Erika (2017). Evolution of Blood Lactate and 90-Day Mortality in Septic Shock. A Post Hoc Analysis of the Finnaki Study. Shock, 47(5), pp. 574-581. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000772

Brander, Lukas; Moerer, Onnen; Hedenstierna, Göran; Beck, Jennifer; Takala, Jukka; Slutsky, Arthur S; Sinderby, Christer (2017). NEURAL CONTROL OF VENTILATION PREVENTS BOTH OVER-DISTENSION AND DE-RECRUITMENT OF EXPERIMENTALLY INJURED LUNGS. Respiratory physiology & neurobiology, 237, pp. 57-67. Elsevier 10.1016/j.resp.2016.12.010

Merz, Tobias; Pereira, Adriano J; Schürch, Roger; Schefold, Joerg C.; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2017). Mitochondrial function of immune cells in septic shock: A prospective observational cohort study. PLoS ONE, 12(6), e0178946. Public Library of Science 10.1371/journal.pone.0178946

Bloch, Andreas; Berger, David; Takala, Jukka (2016). Understanding circulatory failure in sepsis. Intensive care medicine, 42(12), pp. 2077-2079. Springer 10.1007/s00134-016-4514-1

Pettilä, Ville Yrjö Olavi; Jakob, Stephan; Takala, Jukka (2016). The new sepsis/septic shock-3 definition is just not enough - more detailed research is needed. Acta anaesthesiologica Scandinavica, 60(10), pp. 1344-1346. Wiley-Blackwell 10.1111/aas.12777

Carrel, Thierry; Englberger, Lars; Takala, Jukka (2016). What's new in surgical treatment of infective endocarditis? Intensive care medicine, 42(12), pp. 2052-2054. Springer 10.1007/s00134-016-4542-x

Cioccari, Luca; Luethi, Nora; Weber, Ulrike; Hilton, Andrew; Takala, Jukka; Bellomo, Rinaldo (2016). The native cardiac output in human sepsis: a systematic review. Critical care and resuscitation, 18(3), pp. 148-156. College of Intensive Care Medicine of Australia and New Zealand

Eggmann, Sabrina; Verra, Martin L; Luder, Gere; Takala, Jukka; Jakob, Stephan (2016). Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: a study protocol for a randomised controlled trial. Trials, 17, p. 403. BioMed Central 10.1186/s13063-016-1533-8

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Jeger, Victor; Takala, Jukka; Jakob, Stephan (2016). The Effects of Fentanyl on Hepatic Mitochondrial Function. Anesthesia and analgesia, 123(2), pp. 311-325. International Anesthesia Research Society 10.1213/ANE.0000000000001280

Pettilä, Ville Yrjö Olavi; Hjortrup, Peter Buhl; Jakob, Stephan; Wilkman, Erika; Perner, Anders; Takala, Jukka (2016). Control groups in recent septic shock trials: a systematic review. Intensive care medicine, 42(12), pp. 1912-1921. Springer 10.1007/s00134-016-4444-y

Berger, David; Werner Möller, Per; Weber, Alberto; Bloch, Andreas; Bloechlinger, Stefan; Hänggi, Matthias; Sondergaard, Soren; Jakob, Stephan; Magder, Sheldon; Takala, Jukka (2016). Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. American journal of physiology - heart and circulatory physiology, 311(3), H794-H806. American Physiological Society 10.1152/ajpheart.00931.2015

Löffel, Lukas; Burkhard, Fiona C.; Takala, Jukka; Wüthrich, Patrick Yves (2016). Impact of a Potassium-enriched, Chloride-depleted 5% Glucose Solution on Gastrointestinal Function after Major Abdominopelvic Surgery: Results of a Randomized Controlled Trial. Anesthesiology, 125(4), p. 1. Lippincott Williams & Wilkins 10.1097/ALN.0000000000001238

Bakker, Jan; Takala, Jukka (2016). Vasopressor therapy: not like antibiotics! Intensive care medicine, 42(7), pp. 1195-1196. Springer 10.1007/s00134-016-4335-2

Vincent, Jean-Louis; Takala, Jukka; Moreno, Rui P; Sakr, Yasser; Marshall, John C (2016). The Richmond Agitation-Sedation Scale Should Not Be Used to Evaluate Neurologic Function. Critical care medicine, 44(6), e450. Lippincott Williams & Wilkins 10.1097/CCM.0000000000001597

Vincent, Jean-Louis; Shehabi, Yahya; Walsh, Timothy S; Pandharipande, Pratik P; Ball, Jonathan A; Spronk, Peter; Longrois, Dan; Strøm, Thomas; Conti, Giorgio; Funk, Georg-Christian; Badenes, Rafael; Mantz, Jean; Spies, Claudia; Takala, Jukka (2016). Comfort and patient-centred care without excessive sedation: the eCASH concept. Intensive care medicine, 42(6), pp. 962-971. Springer 10.1007/s00134-016-4297-4

Möller, P. W.; Jakob, Stephan M.; Takala, Jukka; Berger, David; Stanga, Zeno (2016). 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016. Critical care (London, England), 20(Suppl 2), p. 94. 10.1186/s13054-016-1208-6

Takala, Jukka; Jakob, Stephan (2016). Oxygen transport in the critically ill. In: Webb, Andrew; Angus, Derek; Finfer, Simon; Gattinoni, Luciano; Singer, Mervyn (eds.) Oxford Textbook of Critical Care (pp. 636-639). Oxford University Press

Takala, Jukka (2016). Resource management and budgeting in critical care. In: Webb, Andrew; Angus, Derek; Finfer, Simon; Gattinoni, Luciano; Singer, Mervyn (eds.) Oxford Textbook of Critical Care (pp. 90-93). Oxford University Press 10.1093/med/9780199600830.003.0021

Zante, Björn; Dietler, Roland; Takala, Jukka (2016). Internal reporting system: we must look behind the curtain. Intensive care medicine, 42(6), p. 1100. Springer 10.1007/s00134-016-4289-4

Berger, David; Blöchlinger, Stefan; von Haehling, Stephan; Doehner, Wolfram; Takala, Jukka; Z'Graggen, Werner Josef; Schefold, Joerg C. (2016). Dysfunction of respiratory muscles in critically ill patients on the intensive care unit. Journal of cachexia, sarcopenia and muscle, 7(4), pp. 403-412. Wiley 10.1002/jcsm.12108

Takala, Jukka (2016). Volume responsive, but does the patient need volume? Intensive care medicine, 42(9), pp. 1461-1463. Springer 10.1007/s00134-015-4172-8

Bechtel-Grosch, Ursina; Béguelin, Charles Antoine; Berezowska, Sabina Anna; Dufour, Jean-François; Takala, Jukka; Schefold, Joerg C. (2016). Fulminant hepatic and multiple organ failure following acute viral tonsillitis: a case report. Journal of medical case reports, 10(7), p. 7. BioMed Central 10.1186/s13256-015-0777-3

Zürcher, Patrick; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Grossholz, Marius; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2016). A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model. BMC neurology, 16, p. 43. BioMed Central 10.1186/s12883-016-0565-8

Berger, David; Takala, Jukka (2016). Hypotension and hypovolemia during hemodialysis: is the usual suspect innocent? Critical care, 20(1), p. 140. BioMed Central 10.1186/s13054-016-1307-4

Pettilä, Ville Yrjö Olavi; Merz, Tobias Michael; Wilkman, Erika; Perner, Anders; Karlsson, Sari; Lange, Theis; Hästbacka, Johanna; Hjortrup, Peter Buhl; Kuitunen, Anne; Jakob, Stephan; Takala, Jukka (2016). Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial. Trials, 17(384), p. 384. BioMed Central 10.1186/s13063-016-1515-x

Berger, David; Werner Möller, Per; Takala, Jukka (2016). Reply to “Letter to the editor: Why persist in the fallacy that mean systemic pressure drives venous return?”. American journal of physiology - heart and circulatory physiology, 311(5), H1336-H1337. American Physiological Society 10.1152/ajpheart.00622.2016

Cioccari, Luca; Gautschi, Matthias; Etter, Reto; Weck, Anja; Takala, Jukka (2015). Further Concerns About Glutamine: A Case Report on Hyperammonemic Encephalopathy. Critical care medicine, 43(10), e458-e460. Lippincott Williams & Wilkins 10.1097/CCM.0000000000001151

Fung, Christian; Inglin, Fabienne; Murek, Michael Konrad; Balmer, Mathias; Abu-Isa, Janine; Z'Graggen, Werner Josef; Ozdoba, Christoph; Gralla, Jan; Jakob, Stephan; Takala, Jukka; Beck, Jürgen; Raabe, Andreas (2015). Reconsidering the logic of World Federation of Neurosurgical Societies grading in patients with severe subarachnoid hemorrhage. Journal of neurosurgery, 124(2), pp. 299-304. American Association of Neurological Surgeons 10.3171/2015.2.JNS14614

Merz, Tobias Michael; Pichler Hefti, Jacqueline Renée; Hefti, Urs; Huber, Andreas; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Changes in mitochondrial enzymatic activities of monocytes during prolonged hypobaric hypoxia and influence of antioxidants: A randomized controlled study. Redox report, 20(5), pp. 234-240. Maney Publishing 10.1179/1351000215Y.0000000007

Bloechlinger, Stefan; Berger, David; Bryner, Jürg; Roost, Eva; Jakob, Stephan; Dünser, Martin W; Takala, Jukka (2015). Changes in Left Ventricular Torsion Early Postoperatively After Aortic Valve Replacement and at Long-Term Follow-up. Journal of cardiothoracic and vascular anesthesia, 29(4), pp. 860-867. Elsevier 10.1053/j.jvca.2015.01.010

Coslovsky, Michael; Takala, Jukka; Exadaktylos, Aristomenis; Martinolli, Luca; Merz, Tobias M (2015). A clinical prediction model to identify patients at high risk of death in the emergency department. Intensive care medicine, 41(6), pp. 1029-1036. Springer 10.1007/s00134-015-3737-x

Bendel, Stepani; Springe, Dirk; Pereira, Adriano José; Grandgirard, Denis; Leib, Stephen; Putzu, Alessandro; Schlickeiser, Jannis; Jakob, Stephan M.; Takala, Jukka; Hänggi, Matthias (2015). Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? BMC anesthesiology, 15(2), p. 2. BioMed Central 10.1186/1471-2253-15-2

Zante, Björn; Reineke, David; Venetz, Philipp; Englberger, Lars; von Tengg-Kobligk, Hendrik; Takala, Jukka; Carrel, Thierry (2015). Biatrial enlargement: 6,000 ml intracardiac blood volume. Intensive care medicine, 41(1), pp. 136-138. Springer 10.1007/s00134-014-3443-0

Ackermann, Karin; Brander, Lukas; Tuchscherer, Daniel; Schröder, Ralph; Jakob, Stephan; Takala, Jukka; Z'Graggen, Werner Josef (2015). Esophageal versus surface recording of diaphragm compound muscle action potential. Muscle & nerve, 51(4), pp. 598-600. John Wiley & Sons 10.1002/mus.24577

Corrêa, Thiago Domingos; Takala, Jukka; Jakob, Stephan (2015). Is lactate clearance impaired in septic shock? Critical care, 19(306), p. 306. BioMed Central 10.1186/s13054-015-1039-x

Corrêa, Thiago Domingos; Jakob, Stephan; Takala, Jukka (2015). Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? Critical care, 19(264), p. 264. BioMed Central 10.1186/s13054-015-0958-x

Turunen, Heidi; Jakob, Stephan; Ruokonen, Esko; Kaukonen, Kirsi-Maija; Sarapohja, Toni; Apajasalo, Marjo; Takala, Jukka (2015). Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care: an economic evaluation. Critical care, 19(67), p. 67. BioMed Central 10.1186/s13054-015-0787-y

Corrêa, Thiago D; Takala, Jukka; Jakob, Stephan (2015). Angiotensin II in septic shock. Critical care, 19(98), p. 98. BioMed Central 10.1186/s13054-015-0802-3

Jeger, Victor; Brandt, Sebastian; Porta, Francesca; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Dose response of endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed research international, 2015, p. 353074. Hindawi Publishing Corporation 10.1155/2015/353074

Marbacher, Serge; Neuschmelting, Volker; Andereggen, Lukas; Widmer, Hans Rudolf; von Gunten, Michael; Takala, Jukka; Jakob, Stephan; Fandino, Javier (2014). Early brain injury linearly correlates with reduction in cerebral perfusion pressure during the hyperacute phase of subarachnoid hemorrhage. Intensive care medicine experimental, 2(1), p. 30. Springer 10.1186/s40635-014-0030-1

Andereggen, Lukas; Neuschmelting, Volker; von Gunten, Michael; Widmer, Hans Rudolf; Takala, Jukka; Jakob, Stephan; Fandino, Javier; Marbacher, Serge (2014). The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects. Journal of visualized experiments(92), e52132. MYJoVE Corporation 10.3791/52132

Hänggi, Matthias; Jakob, Stephan; Takala, Jukka (2014). Sedation level and prevalence of delirium: response to Brummel and Ely. Intensive care medicine, 40(1), p. 136. Springer 10.1007/s00134-013-3092-8

Berger, David; Blöchlinger, Stefan; Takala, Jukka; Sinderby, Christer; Brander, Lukas (2014). Heart-lung interactions during neurally adjusted ventilatory assist. Critical care, 18(5), p. 499. BioMed Central 10.1186/s13054-014-0499-8

Pereira, A. J.; Jeger, V.; Fahrner, R.; Djafarzadeh, Siamak; Lensch, Michael; Takala, Jukka; Jakob, Stephan (2014). Interference of angiotensin II and enalapril with hepatic blood flow regulation. American journal of physiology - gastrointestinal and liver physiology, 307(6), G655-G663. American Physiological Society 10.1152/ajpgi.00150.2014

Corrêa, Thiago D.; Jeger, Victor; Pereira, Adriano José; Takala, Jukka; Djafarzadeh, Siamak; Jakob, Stephan (2014). Angiotensin II in Septic Shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Critical care medicine, 42(8), e550-e559. Lippincott Williams & Wilkins 10.1097/CCM.0000000000000397

Lima, Alexandre; Takala, Jukka (2014). Clinical significance of monitoring perfusion in non-vital organs. Intensive care medicine, 40(7), pp. 1052-1054. Springer 10.1007/s00134-014-3345-1

Takala, Jukka (2014). Reply: Is the Glass of Delirium Half Full or Half Empty? American journal of respiratory and critical care medicine, 189(11), p. 1444. American Lung Association 10.1164/rccm.201404-0642LE

Ackermann, Karin; Bostock, Hugh; Brander, Lukas; Schröder, Ralph; Djafarzadeh, Siamak; Tuchscherer, Daniel; Jakob, Stephan; Takala, Jukka; Z'Graggen, Werner Josef (2014). Early changes of muscle membrane properties in porcine faecal peritonitis. Critical care, 18(4), p. 484. BioMed Central 10.1186/s13054-014-0484-2

Takala, Jukka (2014). Of Delirium and Sedation. American journal of respiratory and critical care medicine, 189(6), pp. 622-624. American Lung Association 10.1164/rccm.201401-0195ED

Jakob, Stephan; Ruokonen, E.; Takala, Jukka (2014). Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients. British journal of anaesthesia, 112(3), pp. 581-582. Oxford University Press 10.1093/bja/aeu032

Etter, Reto; Takala, Jukka; Merz, Tobias Michael (2014). Intensive care without walls - introduction of a Medical Emergency Team system in a Swiss tertiary care centre. Swiss medical weekly, 144(w14027), w14027. EMH Schweizerischer Ärzteverlag 10.4414/smw.2014.14027

Takala, Jukka (2013). Night-time intensivists - waste of resources or failure of process optimization? Critical care, 17(6), p. 472. BioMed Central 10.1186/cc13170

Bloechlinger, Stefan; Berger, David; Bryner, Jürg; Wiegand, Jan; Dünser, Martin W.; Takala, Jukka (2013). Left ventricular torsion abnormalities in septic shock and corrective effect of volume loading: a pilot study. Canadian journal of cardiology, 29(12), pp. 1665-1671. Canadian Cardiology Publications 10.1016/j.cjca.2013.10.007

Dünser, Martin W.; Takala, Jukka; Brunauer, Andreas; Bakker, Jan (2013). Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach. Critical care, 17(5), p. 326. BioMed Central 10.1186/cc12727

Gorrasi, José; Eleftheriadis, Anestis; Takala, Jukka; Brandt, Sebastian; Djafarzadeh, Siamak; Brügger, Lukas; Bracht, Hendrik; Jakob, Stephan (2013). Different Contribution of Splanchnic Organs to Hyperlactatemia in Fecal Peritonitis and Cardiac Tamponade. BioMed research international, 2013, pp. 1-8. Hindawi Publishing Corporation 10.1155/2013/251084

Astin, Ronan; Bentham, Robert; Djafarzadeh, Siamak; Horscroft, James A.; Kuc, Rhoda E.; Leung, Po Sing; Skipworth, James R. A.; Vicencio, Jose M.; Davenport, Anthony P.; Murray, Andrew J.; Takala, Jukka; Jakob, Stephan; Montgomery, Hugh; Szabadkai, Gyorgy (2013). No evidence for a local renin-angiotensin system in liver mitochondria. Scientific Reports, 3(1), p. 2467. Nature Publishing Group 10.1038/srep02467

Takala, Jukka; Hartog, Christiane; Reinhart, Konrad (2013). Safety of modern starches used during surgery: misleading conclusions. Anesthesia and analgesia, 117(2), pp. 527-528. Lippincott Williams & Wilkins 10.1213/ANE.0b013e318296913f

Shehabi, Yahya; Bellomo, Rinaldo; Mehta, Sangeeta; Riker, Richard; Takala, Jukka (2013). Intensive care sedation: the past, present and the future. Critical care, 17(3), p. 322. BioMed Central 10.1186/cc12679

Corrêa, Thiago Domingos; Takala, Jukka; Jakob, Stephan (2013). Target blood pressure in sepsis: between a rock and a hard place. Critical care, 17(3), p. 433. BioMed Central 10.1186/cc12692

Jeger, Victor; Djafarzadeh, Siamak; Jakob, Stephan; Takala, Jukka (2013). Mitochondrial function in sepsis. European journal of clinical investigation, 43(5), pp. 532-542. Wiley-Blackwell 10.1111/eci.12069

Cioccari, Luca; Baur, Hans-Rudolf; Berger, David; Wiegand, Jan; Takala, Jukka; Merz, Tobias Michael (2013). Hemodynamic assessment of critically ill patients using a miniaturized transesophageal echocardiography probe. Critical care, 17(3), R121. BioMed Central 10.1186/cc12793

Corrêa, Thiago Domingos; Vuda, Madhusudanarao; Takala, Jukka; Djafarzadeh, Siamak; Silva, Eliézer; Jakob, Stephan (2013). Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Critical care, 17(1), R21. BioMed Central 10.1186/cc12495

Lehmann, Laura; Bendel, Stepani; Uehlinger, Dominik E; Takala, Jukka; Schafer, Margaret; Reinert, Michael; Jakob, Stephan M (2013). Randomized, Double-Blind Trial of the Effect of Fluid Composition on Electrolyte, Acid-Base, and Fluid Homeostasis in Patients Early After Subarachnoid Hemorrhage. Neurocritical care, 18(1), pp. 5-12. New York, N.Y.: Springer 10.1007/s12028-012-9764-3

Torgersen, Christian-Erik; Meichtry, Jurka; Schmittinger, Christian A; Blöchlinger, Stefan; Jakob, Stephan M; Takala, Jukka; Dünser, Martin Wolfgang (2013). Haemodynamic variables and functional outcome in hypothermic patients following out-of-hospital cardiac arrest. Resuscitation, 84(6), pp. 798-804. Shannon: Elsevier Science Ireland 10.1016/j.resuscitation.2012.10.012

Hänggi, Matthias; Blum, Sina; Brechbuehl, Ruth; Brunello, Anna; Jakob, Stephan; Takala, Jukka (2013). Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC. Intensive care medicine, 39(12), pp. 2171-2179. Springer Berlin Heidelberg 10.1007/s00134-013-3034-5

Jakob, Stephan M; Ruokonen, Esko; Grounds, R Michael; Sarapohja, Toni; Garratt, Chris; Pocock, Stuart J; Bratty, J Raymond; Takala, Jukka; Dexmedetomidine for Long-Term Sedation, Investigators (2012). Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA - the journal of the American Medical Association, 307(11), pp. 1151-60. Chicago, Ill.: American Medical Association 10.1001/jama.2012.304

Vincent, Jean-Louis; Takala, Jukka; Flaatten, Hans (2012). Impact of reimbursement schemes on quality of care: a European perspective. American journal of respiratory and critical care medicine, 185(2), pp. 119-21. New York, N.Y.: American Lung Association 10.1164/rccm.201108-1472ED

Marbacher, Serge; Andereggen, Lukas; Neuschmelting, Volker; Widmer, Hans Rudolf; von Gunten, Michael; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2012). A new rabbit model for the study of early brain injury after subarachnoid hemorrhage. Journal of neuroscience methods, 208(2), pp. 138-145. Amsterdam: Elsevier 10.1016/j.jneumeth.2012.05.010

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Takala, Jukka; Jakob, Stephan M (2012). Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PLoS ONE, 7(9), e45195. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0045195

Marbacher, Serge; Sherif, Camillo; Neuschmelting, Volker; Schläppi, Janine-Ai; Takala, Jukka; Jakob, Stephan; Fandino, Javier (2011). Preliminary results of an ICP-controlled subarachnoid hemorrhage rabbit model for the study of delayed cerebral vasospasm. Acta neurochirurgica - supplementa, 110(Pt 1), pp. 163-5. Wien: Springer 10.1007/978-3-7091-0353-1_28

Merz, Tobias M; Etter, Reto; Mende, Ludger; Barthelmes, Daniel; Wiegand, Jan; Martinolli, Luca; Takala, Jukka (2011). Risk assessment in the first fifteen minutes: a prospective cohort study of a simple physiological scoring system in the emergency department. Critical care, 15(1), R25. London: BioMed Central 10.1186/cc9972

Wiegand, Jan A; Torgersen, Christian; Bloechlinger, Stefan; Takala, Jukka; Dünser, Martin W (2011). Influenza A(H1N1) infection and severe cardiac dysfunction in adults: A case series. Wiener klinische Wochenschrift, 123(3-4), pp. 120-3. Wien: Springer-Verlag 10.1007/s00508-010-1520-0

Takala, Jukka; Ruokonen, Esko; Tenhunen, Jyrki J; Parviainen, Ilkka; Jakob, Stephan M (2011). Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: A multi-center randomized controlled trial. Critical care, 15(3), R148. London: BioMed Central 10.1186/cc10273

Tuchscherer, Daniel; Z'graggen, Werner J; Passath, Christina; Takala, Jukka; Sinderby, Christer; Brander, Lukas (2011). Neurally adjusted ventilatory assist in patients with critical illness-associated polyneuromyopathy. Intensive care medicine, 37(12), pp. 1951-61. Berlin: Springer-Verlag 10.1007/s00134-011-2376-0

Brunello, Anna-Giulia; Haenggi, Matthias; Wigger, Oliver; Porta, Francesca; Takala, Jukka; Jakob, Stephan M (2010). Usefulness of a clinical diagnosis of ICU-acquired paresis to predict outcome in patients with SIRS and acute respiratory failure. Intensive care medicine, 36(1), pp. 66-74. Berlin: Springer-Verlag 10.1007/s00134-009-1645-7

Spirig, Rolf; Djafarzadeh, Siamak; Regueira, Tomas; Shaw, Sidney G; von Garnier, Christophe; Takala, Jukka; Jakob, Stephan M; Rieben, Robert; Lepper, Philipp M (2010). Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions. PLoS ONE, 5(6), e0010983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0010983

Barthelmes, D; Jakob, S M; Laitinen, S; Rahikainen, S; Ahonen, H; Takala, J (2010). Effect of site of lactate infusion on regional lactate exchange in pigs. British journal of anaesthesia, 105(5), pp. 627-34. Oxford: Oxford University Press 10.1093/bja/aeq214

Wyler von Ballmoos, Moritz; Takala, Jukka; Roeck, Margareta; Porta, Francesca; Tueller, David; Ganter, Christoph C; Schröder, Ralph; Bracht, Hendrik; Baenziger, Bertram; Jakob, Stephan M (2010). Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study. Critical care, 14(3), R111. London: BioMed Central 10.1186/cc9060

Dahlqvist, Mats B; Andres, Robert H; Raabe, Andreas; Jakob, Stephan M; Takala, Jukka; Dünser, Martin W (2010). Brain herniation in a patient with apparently normal intracranial pressure: a case report. Journal of medical case reports, 4, p. 297. London: BioMed Central

Daudel, Fritz; Tüller, David; Krähenbühl, Stefanie; Jakob, Stephan M; Takala, Jukka (2010). Pulse pressure variation and volume responsiveness during acutely increased pulmonary artery pressure: an experimental study. Critical care, 14(3), R122. London: BioMed Central 10.1186/cc9080

Marbacher, Serge; Sherif, Camillo; Neuschmelting, Volker; Schläppi, Janine-Ai; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2010). Extra-intracranial blood shunt mimicking aneurysm rupture: intracranial-pressure-controlled rabbit subarachnoid hemorrhage model. Journal of neuroscience methods, 191(2), pp. 227-33. Amsterdam: Elsevier 10.1016/j.jneumeth.2010.07.004

Jakob, Stephan M; Knuesel, Rafael; Tenhunen, Jyrki J; Pradl, Richard; Takala, Jukka (2010). Increasing abdominal pressure with and without PEEP: effects on intra-peritoneal, intra-organ and intra-vascular pressures. BMC gastroenterology, 10, p. 70. London: BioMed Central 10.1186/1471-230X-10-70

Brügger, Lukas E; Beldi, Guido; Beck, Mario; Porta, Francesca; Bracht, Hendrik; Candinas, Daniel; Takala, Jukka; Jakob, Stephan M (2010). Splanchnic vasoregulation after major abdominal surgery in pigs. World journal of surgery, 34(9), pp. 2057-63. New York, N.Y.: Springer

Ruokonen, Esko; Parviainen, Ilkka; Jakob, Stephan M; Nunes, Silvia; Kaukonen, Maija; Shepherd, Stephen T; Sarapohja, Toni; Bratty, J Raymond; Takala, Jukka (2009). Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation. Intensive care medicine, 35(2), pp. 282-90. Berlin: Springer-Verlag 10.1007/s00134-008-1296-0

Neuschmelting, Volker; Fathi, Ali-Reza; Hidalgo Staub, Eveline Teresa; Marbacher, Serge; Schroth, Gerhard; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2009). Norepinephrine-induced hypertension dilates vasospastic basilar artery after subarachnoid haemorrhage in rabbits. Acta neurochirurgica, 151(5), pp. 487-93. Wien: Springer Vienna 10.1007/s00701-009-0287-4

Brandt, S; Regueira, T; Bracht, H; Porta, F; Takala, J; Hiltebrand, LB; Beldi, G; Lepper, MP; Brügger, LE; Kessler, U; Jakob St, M (2009). Effect of fluid resuscitation on mortality and organ function in experimental sepsis models. Critical care, 13(6), R186. London: BioMed Central 10.1186/cc8179

Daudel, Fritz; Kessler, Ulf; Folly, Hélène; Lienert, Jasmin S; Takala, Jukka; Jakob, Stephan M (2009). Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study. Critical care, 13(2), R42. London: BioMed Central 10.1186/cc7765

Dünser, Martin W; Takala, Jukka; Ulmer, Hanno; Mayr, Viktoria D; Luckner, Günter; Jochberger, Stefan; Daudel, Fritz; Lepper, Philipp; Hasibeder, Walter R; Jakob, Stephan M (2009). Arterial blood pressure during early sepsis and outcome. Intensive care medicine, 35(7), pp. 1225-33. Berlin: Springer-Verlag 10.1007/s00134-009-1427-2

Dünser, Martin W; Ruokonen, Esko; Pettilä, Ville; Ulmer, Hanno; Torgersen, Christian; Schmittinger, Christian A; Jakob, Stephan; Takala, Jukka (2009). Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial. Critical care, 13(6), R181. London: BioMed Central 10.1186/cc8167

Haenggi, Matthias; Ypparila-Wolters, Heidi; Hauser, Kathrin; Caviezel, Claudio; Takala, Jukka; Korhonen, Ilkka; Jakob, Stephan M (2009). Intra- and inter-individual variation of BIS-index and Entropy during controlled sedation with midazolam/remifentanil and dexmedetomidine/remifentanil in healthy volunteers: an interventional study. Critical care, 13(1), R20. London: BioMed Central 10.1186/cc7723

Torgersen, Christian; Schmittinger, Christian A; Wagner, Sarah; Ulmer, Hanno; Takala, Jukka; Jakob, Stephan M; Dünser, Martin W (2009). Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort study. Critical care, 13(5), R157. London: BioMed Central 10.1186/cc8114

Takala, Jukka; Jakob, Stephan M (2009). Shedding light on microcirculation? Intensive care medicine, 35(3), pp. 394-6. Berlin: Springer-Verlag 10.1007/s00134-008-1386-z

Porta, Francesca; Bracht, Hendrik; Weikert, Christian; Beck, Mario; Takala, Jukka; Brandt, Sebastian; Hiltebrand, Luzius B; Jakob, Stephan M (2009). Effects of endotoxin and catecholamines on hepatic mitochondrial respiration. Inflammation, 32(5), pp. 315-21. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10753-009-9138-y

Bracht, Hendrik; Krejci, Vladimir; Hiltebrand, Luzius; Brandt, Sebastian; Sigurdsson, Gisli; Ali, Syed Z; Takala, Jukka; Jakob, Stephan M (2008). Orthogonal polarization spectroscopy to detect mesenteric hypoperfusion. Intensive care medicine, 34(10), pp. 1883-90. Berlin: Springer-Verlag 10.1007/s00134-008-1130-8

Regueira, Tomas; Bänziger, Bertram; Djafarzadeh, Siamak; Brandt, Sebastian; Gorrasi, Jose; Takala, Jukka; Lepper, Philipp M; Jakob, Stephan M (2008). Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. Critical care, 12(4), R88. London: BioMed Central 10.1186/cc6956

Hänggi, Matthias; Ypparila-Wolters, Heidi; Bieri, Christine; Steiner, Carola; Takala, Jukka; Korhonen, Ilkka; Jakob, Stephan M (2008). Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study. Critical care, 12(5), R119. London: BioMed Central 10.1186/cc7015

Takala, Jukka; Dellinger, R Philip; Koskinen, Kati; St Andre, Arthur; Read, Martyn; Levy, Mitchell; Jakob, Stephan M; Mello, Patricia Veiga C; Friolet, Raymond; Ruokonen, Esko (2008). Development and simultaneous application of multiple care protocols in critical care: a multicenter feasibility study. Intensive care medicine, 34(8), pp. 1401-10. Berlin: Springer-Verlag 10.1007/s00134-008-1084-x

Merz, Tobias M; Schär, Pascale; Bühlmann, Michael; Takala, Jukka; Rothen, Hans U (2008). Resource use and outcome in critically ill patients with hematological malignancy: a retrospective cohort study. Critical care, 12(3), R75. London: BioMed Central 10.1186/cc6921

Suter, Peter M; Takala, Jukka (2008). Science, medicine and industry: are we getting out of the black hole in sepsis research? Intensive care medicine, 34(11), pp. 1950-4. Berlin: Springer-Verlag 10.1007/s00134-008-1302-6

Bracht, Hendrik; Hänggi, Matthias; Jeker, Barbara; Wegmüller, Ninja; Porta, Francesca; Tüller, David; Takala, Jukka; Jakob, Stephan M (2007). Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study. Critical care, 11(1), R2. London: BioMed Central 10.1186/cc5144

Rothen, Hans U; Stricker, Kay; Einfalt, Johanna; Bauer, Peter; Metnitz, Philip G H; Moreno, Rui P; Takala, Jukka (2007). Variability in outcome and resource use in intensive care units. Intensive care medicine, 33(8), pp. 1329-36. Berlin: Springer-Verlag 10.1007/s00134-007-0690-3

Takala, Jukka (2007). Hypoxemia due to increased venous admixture: influence of cardiac output on oxygenation. Intensive care medicine, 33(5), pp. 908-11. Berlin: Springer Berlin Heidelberg 10.1007/s00134-007-0546-x

Porta, Francesca; Takala, Jukka; Weikert, Christian; Bracht, Hendrik; Kolarova, Anna; Lauterburg, Bernhard H; Borotto, Erika; Jakob, Stephan M (2006). Effects of prolonged endotoxemia on liver, skeletal muscle and kidney mitochondrial function. Critical care, 10(4), R118. London: BioMed Central 10.1186/cc5013

Takala, Jukka (2006). The pulmonary artery catheter: the tool versus treatments based on the tool. Critical care, 10(4), p. 162. London: BioMed Central 10.1186/cc5021

Collaborative Study Group on Perioperative ScvO2 Monitoring (KIM, H; Haenggi, M; Jakob, SM; Loher, S; Raeber, C; Takala, J) (2006). Multicentre study on peri- and postoperative central venous oxygen saturation in high-risk surgical patients. Critical care, 10(6), R158. London: BioMed Central 10.1186/cc5094

Mayr, Viktoria D; Dünser, Martin W; Greil, Veronika; Jochberger, Stefan; Luckner, Günter; Ulmer, Hanno; Friesenecker, Barbara E; Takala, Jukka; Hasibeder, Walter R (2006). Causes of death and determinants of outcome in critically ill patients. Critical care, 10(6), R154. London: BioMed Central 10.1186/cc5086

Pachl, J; Svoboda, P; Jacobs, F; Vandewoude, K; van der Hoven, B; Spronk, P; Masterson, G; Malbrain, M; Aoun, M; Garbino, J; Takala, J; Drgona, L; Burnie, J; Matthews, R; Mycograb, Invasive Candidiasis Study Group (2006). A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis. Clinical infectious diseases, 42(10), pp. 1404-13. Cary, N.C.: The University of Chicago Press 10.1086/503428

Uehlinger, Dominik E; Jakob, Stephan M; Ferrari, Paolo; Eichelberger, Markus; Huynh-Do, Uyen; Marti, Hans-Peter; Mohaupt, Markus G; Vogt, Bruno; Rothen, Hans Ulrich; Regli, Bruno; Takala, Jukka; Frey, Felix J (2005). Comparison of continuous and intermittent renal replacement therapy for acute renal failure. Nephrology, dialysis, transplantation, 20(8), pp. 1630-1637. Oxford University Press 10.1093/ndt/gfh880

Knüsel, Rafael Matthias; Jakob, Stephan M.; Brander, Lukas; Bracht, Hendrik; Siegenthaler, Andreas; Takala, Jukka (2003). Changes in regional blood flow and pCO2 gradients during isolated abdominal aortic blood flow reduction. Intensive care medicine, 29(12), pp. 2255-2265. Springer-Verlag 10.1007/s00134-003-1954-1

Röck, Margareta Anna; Jakob, Stephan M.; Böhlen, Thomas; Brander, Lukas; Knuesel, Rafael; Takala, Jukka (2003). Change in stroke volume in response to fluid challenge: assessment using esophageal Doppler. Intensive care medicine, 29(10), pp. 1729-1735. Springer-Verlag 10.1007/s00134-003-1720-4

Nunes, Silvia; Ruokonen, Esko; Takala, Jukka (2003). Pulmonary capillary pressures during the acute respiratory distress syndrome. Intensive care medicine, 29(12), pp. 2174-2179. Springer-Verlag 10.1007/s00134-003-2036-0

Roth, Thierry; Kipfer, Beat; Takala, Jukka; Schmid, Ralph A. (2002). Delayed heart perforation after blunt trauma. European journal of cardio-thoracic surgery, 21(1), pp. 121-123. Elsevier Science B.V. 10.1016/S1010-7940(01)01054-5

Uusaro, A.; Lahtinen, P.; Parviainen, I.; Takala, J. (2000). Gastric mucosal end‐tidal Pco2 difference as a continuous indicator of splanchnic perfusion. British journal of anaesthesia, 85(4), pp. 563-569. Oxford University Press 10.1093/bja/85.4.563

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