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Leumann, Christian J. (2021). Swiss Science: Quo Vadis after Exclusion from the European Framework Program? CHIMIA, 75(9), pp. 810-811. Schweizerische Chemische Gesellschaft 10.2533/chimia.2021.810
Röthlisberger, Pascal; Levi-Acobas, Fabienne; Leumann, Christian J.; Hollenstein, Marcel (2020). Enzymatic synthesis of biphenyl-DNA oligonucleotides. Bioorganic & medicinal chemistry, 28(11), p. 115487. Elsevier 10.1016/j.bmc.2020.115487
Levi-Acobas, Fabienne; Katolik, Adam; Röthlisberger, Pascal; Cokelaer, Thomas; Sarac, Ivo; Damha, Masad J.; Leumann, Christian J.; Hollenstein, Marcel (2019). Compatibility of 5-ethynyl-2’F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers. Organic & biomolecular chemistry, 17(35), pp. 8083-8087. Royal Society of Chemistry 10.1039/C9OB01515A
Schuermann, David; Scheidegger, Simon P.; Weber, Alain R.; Bjørås, Magnar; Leumann, Christian J.; Schär, Primo (2016). 3CAPS – a structural AP-site analogue as a tool to investigate DNA base excision repair. Nucleic acids research, 44(5), pp. 2187-2198. Information Retrieval Ltd. 10.1093/nar/gkv1520
Istrate, Alena; Medvecky, Michal; Leumann, Christian J. (2015). 2′-Fluorination of Tricyclo-DNA Controls Furanose Conformation and Increases RNA Affinity. Organic letters, 17(8), pp. 1950-1953. American Chemical Society 10.1021/acs.orglett.5b00662
Calabretta, Alessandro; Küpfer, Pascal A.; Leumann, Christian J. (2015). The effect of RNA base lesions on mRNA translation. Nucleic acids research, 43(9), pp. 4713-4720. Information Retrieval Ltd. 10.1093/nar/gkv377
Dugovic, Branislav; Wagner, Michael; Leumann, Christian J. (2014). Structure/affinity studies in the bicyclo-DNA series: Synthesis and properties of oligonucleotides containing bcen-T and iso-tricyclo-T nucleosides. Beilstein journal of organic chemistry, 10, pp. 1840-1847. Beilstein-Institut 10.3762/bjoc.10.194
Röthlisberger, Pascal; Wojciechowski, Filip; Leumann, Christian J. (2013). Enhancement of excess electron transfer efficiency in DNA containing a phenothiazine donor and multiple stable phenanthrenyl base pairs. Chemistry: a European journal, 19(35), pp. 11518-11521. Wiley 10.1002/chem.201301983
Gerber, Anna-Barbara; Leumann, Christian J. (2013). Synthesis and properties of isobicyclo-DNA. Chemistry - a European journal, 19(22), pp. 6990-7006. Wiley-VCH 10.1002/chem.201300487
Calabretta, Alessandro; Leumann, Christian J. (2013). Base pairing and miscoding properties of 1,N(6)-ethenoadenine- and 3,N(4)-ethenocytosine-containing RNA oligonucleotides. Biochemistry, 52(11), pp. 1990-1997. American Chemical Society 10.1021/bi400116y
Stoop, Matthias; Désiron, Camille; Leumann, Christian J. (2013). Nucleic acid sensing by an orthogonal reporter system based on homo-DNA. Artificial DNA: PNA & XNA, 4(1), pp. 28-33. Landes Bioscience 10.4161/adna.24227
Stucki, Silvan R.; Désiron, Camille; Nyakas, Adrien; Marti, Simon; Leumann, Christian J.; Schürch, Stefan (2013). Gas-phase Dissociation of homo-DNA Oligonucleotides. Journal of the American Society for Mass Spectrometry, 24(12), pp. 1997-2006. Springer-Verlag 10.1007/s13361-013-0729-3
Hollenstein, Marcel; Wojciechowski, Filip; Leumann, Christian J. (2012). Polymerase incorporation of pyrene-nucleoside triphosphates. Bioorganic and medicinal chemistry letters, 22(13), pp. 4428-4430. New York, N.Y.: Pergamon 10.1016/j.bmcl.2012.04.101
Wojciechowski, Filip; Lietard, Jory; Leumann, Christian J. (2012). 2-Pyrenyl-DNA: Synthesis, Pairing, and Fluorescence Properties. Organic letters, 14(20), pp. 5176-5179. Washington, D.C.: American Chemical Society 10.1021/ol302150a
Tanakaa, Mikiei; Jaruga, Pawel; Küpfer, Pascal A.; Leumann, Christian J.; Dizdaroglu, Miral; Sonntag, William E.; Chock, P. Boon (2012). RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria. Free radical biology & medicine, 53(4), pp. 854-862. San Diego, Calif.: Elsevier 10.1016/j.freeradbiomed.2012.05.044
Haziri, Arben I.; Leumann, Christian J. (2012). Synthesis and Pairing Properties of Oligodeoxynucleotides Containing Bicyclo-RNA and Bicyclo-ANA Modifications. Journal of organic chemistry, 77(14), pp. 5861-5869. Washington, D.C.: American Chemical Society 10.1021/jo300554w
Murray, Sue; Ittig, Damian; Koller, Erich; Berdeja, Andres; Chappell, Alfred; Prakash, Thazha P.; Norrbom, Michaela; Swayze, Eric E.; Leumann, Christian J.; Seth, Punit P. (2012). TricycloDNA-modified oligo-2′-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues - a comparative study of oligonucleotide length, design and chemistry. Nucleic acids research, 40(13), pp. 6135-6143. London: Oxford University Press 10.1093/nar/gks273
Lietard, Jory; Leumann, Christian J. (2012). Synthesis, Pairing, and Cellular Uptake Properties of C(6′)-Functionalized Tricyclo-DNA. Journal of organic chemistry, 77(10), pp. 4566-4577. Washington, D.C.: American Chemical Society 10.1021/jo300648u
Yaren, Oezlem; Röthlisberger, Pascal; Leumann, Christian J. (2012). Synthesis and Incorporation into Oligodeoxynucleotides of Carbocyclic exo-Amino Nucleosides. Synthesis - journal of synthetic organic chemistry, 44(07), pp. 1011-1025. Stuttgart: Thieme 10.1055/s-0031-1289737
Tanaka, Mikiei; Han, Song; Küpfer, Pascal A.; Leumann, Christian J.; Sonntag, William E. (2011). Quantification of oxidized levels of specific RNA species using an aldehyde reactive probe. Analytical biochemistry, 417(1), pp. 142-148. San Diego, Calif.: Elsevier 10.1016/j.ab.2011.05.038
Tanaka, Mikiei; Song, Han; Küpfer, Pascal A.; Leumann, Christian J.; Sonntag, William E. (2011). An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe. Free radical research, 45(2), pp. 237-247. London: Informa Healthcare 10.3109/10715762.2010.535529
Ittig, Damian; Gerber, Anna-Barbara; Leumann, Christian J. (2011). Position-dependent effects on stability in tricyclo-DNA modified oligonucleotide duplexes. Nucleic acids research, 39(1), pp. 373-380. London: Oxford University Press 10.1093/nar/gkq733
Küpfer, Pascal A.; Leumann, Christian J. (2011). Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine. Nucleic acids research, 39(21), pp. 9422-9432. London: Oxford University Press 10.1093/nar/gkr673
Lietard, Jory; Ittig, Damian; Leumann, Christian J. (2011). Synthesis, binding and cellular uptake properties of oligodeoxynucleotides containing cationic bicyclo-thymidine residues. Bioorganic & medicinal chemistry, 19(19), pp. 5869-5875. Amsterdam: Elsevier 10.1016/j.bmc.2011.08.022
Stoop, Matthias; Leumann, Christian J. (2011). Homo-DNA templated chemistry and its application to nucleic acid sensing. Chemical communications, 47(26), pp. 7494-7496. Cambridge: Royal Society of Chemistry 10.1039/C1CC11469G
Wojciechowski, Filip; Leumann, Christian J. (2011). Alternative DNA base-pairs: from efforts to expand the genetic code to potential material applications. Chemical Society reviews, 40(12), pp. 5669-5679. London: Royal Society of Chemistry 10.1039/C1CS15027H
Yaren, Oezlem; Mosimann, Markus; Leumann, Christian J. (2011). A Parallel Screen for the Discovery of Novel DNA Base Pairs. Angewandte Chemie (International ed.), 50(8), pp. 1935-1938. Weinheim: Wiley-VCH 10.1002/anie.201005300
Haziri, Arben I.; Silhar, Peter; Renneberg, Dorte; Leumann, Christian J. (2010). Synthesis of the Sugar Building Block of Bicyclo-RNA. Synthesis - journal of synthetic organic chemistry, 2010(05), pp. 823-827. Stuttgart: Thieme 10.1055/s-0029-1218650
Ittig, Damian; Luisier, Samuel; Weiler, Jan; Schümperli, Daniel; Leumann, Christian J. (2010). Improving gene silencing of siRNAs via tricyclo-DNA modification. Artificial DNA, PNA & XNA, 1(1), pp. 9-16. Austin, Tex.: Landes Bioscience 10.4161/adna.1.1.11385
Luisier, Samuel; Leumann, Christian J. (2010). Screening the Structural Space of Bicyclo-DNA: Synthesis and Properties of Bicyclo-DNA Functionalized at C(6’). Heterocycles, 82(1), pp. 775-790. Amsterdam: Elsevier Science 10.3987/com-10-s(e)65
Silhár, Peter; Leumann, Christian J. (2010). Parallel synthesis and nucleic acid binding properties of C(6')-[alpha]-functionalized bicyclo-DNA. Bioorganic & medicinal chemistry, 18(22), pp. 7786-7793. Amsterdam: Elsevier 10.1016/j.bmc.2010.09.064
Tanaka, Mikiei; Han, Song; Kupfer, Pascal A.; Leumann, Christian J.; Chock, Boon; Sonntag, William E. (2010). Identification of Selectively Damaged mRNA in Response to Oxidative Stress: Characterization of Abasic sites using an Aldehyde Reactive Probe. Free radical biology & medicine, 49(Supplement), S172. San Diego, Calif.: Elsevier 10.1016/j.freeradbiomed.2010.10.490
Kaufmann, Marco; Gisler, Michael; Leumann, Christian J. (2009). Stable cyclohexyl-phenyl recognition in the center of a DNA duplex. Angewandte Chemie (International ed.), 48(21), pp. 3810-3813. Weinheim: Wiley-VCH 10.1002/anie.200900153
Grigorenko, Nikolaj A.; Leumann, Christian J. (2009). 2-Phenanthrenyl-DNA: Synthesis, Pairing and Fluorescence Properties. Chemistry - a European journal, 15(3), pp. 639-645. Weinheim: Wiley-VCH 10.1002/chem.200801135
Stauffiger, Andrea; Leumann, Christian J. (2009). Screening the structural space of bicyclo-DNA: Synthesis and thermal melting properties of bc4,3-DNA. European journal of organic chemistry, 2009(8), pp. 1153-1162. Weinheim: Wiley-VCH 10.1002/ejoc.200801034
Grigorenko, Nikolaj A.; Leumann, Christian J. (2008). Excess Electron Transport through a Stable Phenanthrenyl Pair in DNA. Chemical communications(42), p. 5417. Cambridge: Royal Society of Chemistry 10.1039/b810751c
Luisier, Samuel; Leumann, Christian J. (2008). Synthesis of bicyclo-DNA nucleosides with additional functionalization in the carbocyclic ring. CHIMIA, 62(4), pp. 270-272. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2008.270
Johar, Zeena; Zahn, Alain; Leumann, Christian J.; Jaun, Bernhard (2008). Solution structure of a DNA duplex containing a biphenyl base-pair. Chemistry - a European journal, 14(4), pp. 1080-1086. Weinheim: Wiley-VCH 10.1002/chem.200701304
Pallan, Pradeep S.; Ittig, Damian; Héroux, Annie; Wawrzak, Zdzislaw; Leumann, Christian J.; Egli, Martin (2008). Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles. Chemical communications(7), pp. 883-885. Cambridge: Royal Society of Chemistry 10.1039/b716390h
Luisier, Samuel; Leumann, Christian J. (2008). Screening the Structural and Functional Properties of Bicyclo-DNA: bcox-DNA. ChemBioChem, 9(14), pp. 2244-2253. Weinheim: Wiley-VCH 10.1002/cbic.200800322
Mayer, Alain; Leumann, Christian J. (2007). Pyrrolidino-DNA with bases corresponding to the 2-oxo deletion mutants of thymine and cytosine: synthesis and triplex forming properties. European journal of organic chemistry, 2007(24), pp. 4038-4049. Weinheim: Wiley-VCH 10.1002/ejoc.200700217
Stoop, Matthias; Zahn, Alain; Leumann, Christian J. (2007). A fluorescence quencher pair for DNA hybridization studies based on hydrophobic base surrogates. Tetrahedron, 63(17), pp. 3440-3449. Kidlington, UK: Elsevier Science 10.1016/j.tet.2006.12.095
Zahn, Alain; Leumann, Christian J. (2007). Biphenyl-DNA. CHIMIA, 61(4), pp. 159-160. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2007.159
Küpfer, Pascal A.; Crey-Desbiolles, Caroline; Leumann, Christian J. (2007). Trans-lesion synthesis and RNase H activity by reverse transcriptases on a true abasic RNA template. Nucleic acids research, 35(20), pp. 6846-6853. London: Information Retrieval Ltd. 10.1093/nar/gkm767
Stauffiger, Andrea; Leumann, Christian J. (2007). Synthesis of the bicyclo-[4.3.0]thymidyl nucleoside via Pd(II)-mediated ring expansion chemistry. Nucleosides, nucleotides & nucleic acids, 26(6-7), pp. 615-619. Philadelphia, Pa.: Taylor & Francis 10.1080/15257770701490407
Küpfer, Pascal A.; Leumann, Christian J. (2007). Photochemically induced RNA and DNA abasic sites. Nucleosides, nucleotides & nucleic acids, 26(8-9), pp. 1177-1180. Philadelphia, Pa.: Taylor & Francis 10.1080/15257770701527711
Buchini, Sabrina; Leumann, Christian J. (2006). 2-O-Aminoethyl-oligoribonucleotides containing novel base analogues: synthesis and triple-helix formation at pyrimidine/purine inversion sites. European journal of organic chemistry, 2006(14), pp. 3152-3168. Weinheim: Wiley-VCH 10.1002/ejoc.200600182
Zahn, Alain; Leumann, Christian J. (2006). Synthesis of Functionalized Biphenyl-C-Nucleosides and their Incorporation into Oligodeoxynucleotides. Bioorganic & medicinal chemistry, 14(18), pp. 6174-6188. Amsterdam: Elsevier 10.1016/j.bmc.2006.05.072
Scheidegger, Simon P.; Leumann, Christian J. (2006). Synthesis and Pairing Properties of alpha-tricyclo-DNA. Chemistry - a European journal, 12(31), pp. 8014-8023. Weinheim: Wiley-VCH 10.1002/chem.200600597
Egli, Martin; Pallan, Pradeep S.; Pattanayek, Rekha; Wilds, Christopher J.; Lubini, Paolo; Minasov, George; Dobler, Max; Leumann, Christian J.; Eschenmoser, Albert (2006). Crystal structure of homo-DNA and Nature s choice of pentose over hexose in the genetic system. Journal of the American Chemical Society, 128(33), pp. 10847-10856. Washington, D.C.: American Chemical Society 10.1021/ja062548x
Küpfer, Pascal A.; Leumann, Christian J. (2006). The chemical stability of abasic RNA compared to abasic DNA. Nucleic acids research, 35(1), pp. 58-68. London: Oxford University Press 10.1093/nar/gkl948
Brotschi, Christine; Leumann, Christian J. (2005). RNA duplexes with biphenyl substituents as base replacements are less stable than DNA duplexes. Chemical communications(15), pp. 2023-2025. Royal Society of Chemistry 10.1039/B419278H
Brotschi, Christine; Mathis, Gérald; Leumann, Christian J. (2005). Bipyridyl- and biphenyl-DNA: A recognition motif based on interstrand aromatic stacking. Chemistry - a European journal, 11(6), pp. 1911-1923. Wiley-VCH 10.1002/chem.200400858
Crey-Desbiolles, Caroline; Ahn, Dae-Ro; Leumann, Christian J. (2005). Molecular beacons with a homo-DNA stem: improving target selectivity. Nucleic acids research, 33(8), e77. Oxford University Press 10.1093/nar/gni076
Hollenstein, Marcel; Leumann, Christian J. (2005). Fluorinated olefinic peptide nucleic acid: synthesis and pairing properties with complementary DNA. Journal of organic chemistry, 70(8), pp. 3205-3217. American Chemical Society 10.1021/jo047753e
Ittig, Damian; Renneberg, Dorte; Vonlanthen, David; Luisier, Samuel; Leumann, Christian J. (2005). Oligonucleotide analogues: From supramolecular principles to biological properties. Collection Symposium Series, 7, pp. 21-26. Prague: Academy of Sciences of the Czech Republic
Küpfer, Pascal A.; Leumann, Christian J. (2005). RNA abasic sites: preparation and trans-lesion synthesis by HIV-1 reverse transcriptase. ChemBioChem, 6(11), pp. 1970-1973. Wiley-VCH 10.1002/cbic.200500204
Leumann, Christian J. (2005). Tuning Molecular Recognition of RNA and DNA via Sugar Modification. CHIMIA, 59(11), pp. 776-779. Bern: Schweizerische Chemische Gesellschaft
Mayer, Alain; Häberli, Adrian; Leumann, Christian J. (2005). Synthesis and triplex forming properties of pyrrolidino pseudoisocytidine containing oligodeoxynucleotides. Organic & biomolecular chemistry, 3(9), pp. 1653-1658. Royal Society of Chemistry 10.1039/B502799C
Mosimann, Markus; Küpfer, Pascal A.; Leumann, Christian J. (2005). Synthesis and incorporation into DNA of a chemically stable, functional abasic site analogue. Organic letters, 7(23), pp. 5211-5214. American Chemical Society 10.1021/ol052045g
Zahn, Alain; Brotschi, Christine; Leumann, Christian J. (2005). Pentafluorophenyl phenyl interaction in biphenyl DNA. Chemistry - a European journal, 11(7), pp. 2125-2129. Wiley-VCH
Renneberg, Dorte; Bouliong, Emilie; Reber, Ulrich; Schümperli, Daniel; Leumann, Christian J. (2002). Antisense properties of tricyclo-DNA. Nucleic acids research, 30(13), pp. 2751-2757. Oxford University Press 10.1093/nar/gkf412
Küpfer, Pascal A.; Leumann, Christian J. (2014). Oxidative Damage on RNA Nucleobases. In: Erdmann, Volker A.; Markiewicz, Wojciech T.; Barciszewski, Jan (eds.) Chemical Biology of Nucleic Acids. RNA Technologies (pp. 75-94). Heidelberg: Springer 10.1007/978-3-642-54452-1_5
Robin, Valerie; Ittig, Damian; Voit, Thomas; Leumann, Christian J.; Garcia, Luis (22 October 2012). SMN rescue by using oligonucleotides of tricyclo-DNA to induce exon 7 inclusion in SMN2 mRNA. Human gene therapy, 23(10), A37-A38. Mary Ann Liebert Inc.
Leumann, Christian J. (2011). Shaping Nucleic Acids for Applications in Therapy: The Tricyclo-DNA Story - an Update. In: Hocek, M. (ed.) Chemistry of Nucleic Acid Components, Cesky-Krumlov, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic. Prague.
Ittig, Damian; Schümperli, Daniel; Leumann, Christian J. (2008). Tc-DNA modified siRNA. Nucleic Acids Symposium Series, 52(1), pp. 501-502. Oxford University Press 10.1093/nass/nrn254
Scheidegger, Simon P.; Leumann, Christian J. (2008). Strand invasion properties and serum stability of a-tricyclo-DNA. Nucleic Acids Symposium Series, 52(1), pp. 139-140. Oxford University Press 10.1093/nass/nrn071
Stauffiger, Andrea; Leumann, Christian J. (2008). Synthesis and structural analysis of [4.3.0]-bicyclothymidine. Nucleic Acids Symposium Series, 52(1), pp. 267-268. Oxford University Press 10.1093/nass/nrn135
Luisier, Samuel; Silhar, Peter; Leumann, Christian J. (2008). Highly beta-selective, N-iodosuccinimide-mediated nucleosidation to bicyclo- and tricyclo-nucleosides. Nucleic Acids Symposium Series, 52(1), pp. 581-582. Oxford University Press 10.1093/nass/nrn294
