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Adamcik, Stefan; Ahler, Markus; Gioutsos, Konstantinos; Schmid, Ralph; Kocher, Gregor (2017). Repair of sternoclavicular joint dislocations with FiberWire®. Archives of orthopaedic and trauma surgery, 137(3), pp. 341-345. Springer 10.1007/s00402-017-2632-z
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Adamcik, Stefan; Ahler, Markus; Gioutsos, Konstantinos; Schmid, Ralph; Kocher, Gregor (2017). Repair of sternoclavicular joint dislocations with FiberWire®. Archives of orthopaedic and trauma surgery, 137(3), pp. 341-345. Springer 10.1007/s00402-017-2632-z
Yang, Haitang; Ma, Wenyan; Sun, Beibei; Fan, Liwen; Xu, Ke; Hall, Sean; Al-Hurani, Mohammad; Schmid, Ralph A.; Peng, Ren-Wang; Hida, Toyoaki; Wang, Zhexin; Yao, Feng (2021). Smoking signature is superior to programmed death-ligand 1 expression in predicting pathological response to neoadjuvant immunotherapy in lung cancer patients. Translational lung cancer research, 10(9), pp. 3807-3822. AME Publishing 10.21037/tlcr-21-734
Yang, Haitang; Al-Hurani, Mohammad; Xu, Jianlin; Fan, Liwen; Schmid, Ralph; Zhao, Heng; Yao, Feng (2021). pN1 but not pN0/N2 predicts survival benefits of prophylactic cranial irradiation in small-cell lung cancer patients after surgery. Annals of translational medicine, 9(7), p. 562. AME Publishing Company 10.21037/atm-20-6984
Kocher, Gregor; Al-Hurani, Mohammad; Dorn, Patrick; Lutz, Jon (2020). Thoracoscopic diaphragm plication. Multimedia Manual of Cardiothoracic Surgery, 2020 Oxford University Press 10.1510/mmcts.2020.054
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Blom, Rebecca Agaatha Maria; Amacker, Mario; Moser, Christian; van Dijk, R Maarten; Bonetti, Raffaela; Seydoux, Emilie; Hall, Sean; von Garnier, Christophe; Blank, Fabian (2017). Virosome-bound antigen enhances DC-dependent specific CD4(+) T cell stimulation, inducing a Th1 and Treg profile in vitro. Nanomedicine : nanotechnology, biology, and medicine, 13(5), pp. 1725-1737. Elsevier 10.1016/j.nano.2017.02.004
Blom, Rebecca Agaatha Maria; Erni, Silvia T; Krempaská, Kristína; Schaerer, Olivier; van Dijk, R Maarten; Amacker, Mario; Moser, Christian; Hall, Sean; Von Garnier, Christophe; Blank, Fabian (2016). A Triple Co-Culture Model of the Human Respiratory Tract to Study Immune-Modulatory Effects of Liposomes and Virosomes. PLoS ONE, 11(9), e0163539. Public Library of Science 10.1371/journal.pone.0163539
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943
Azenha Figueiredo, Luís Filipe; Schmid, Ralph; Kocher, Gregor (2017). Complex Tracheal Repair after Severe Tracheal Rupture during Percutaneous Dilatational Tracheostomy. Case reports journal, 1(1), 001. The Biomedica
Kocher, Gregor; Sharafi, Siamak; Azenha Figueiredo, Luis Filipe; Schmid, Ralph (2016). Chest wall stabilization in ventilator-dependent traumatic flail chest patients: who benefits? European journal of cardio-thoracic surgery, 51(4), pp. 696-701. Oxford University Press 10.1093/ejcts/ezw365
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Jafari, Morteza; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Schmid, Ralph; Geiser, Thomas; Gazdhar, Amiq; Hunger, Robert (2018). Efficacy of In Vivo Electroporation-Mediated IL-10 Gene Delivery on Survival of Skin Flaps. The Journal of Membrane Biology, 251(2), pp. 211-219. Springer 10.1007/s00232-017-9974-x
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Wang, Xiangxue; Bera, Kaustav; Barrera, Cristian; Zhou, Yu; Lu, Cheng; Vaidya, Pranjal; Fu, Pingfu; Yang, Michael; Schmid, Ralph Alexander; Berezowska, Sabina; Choi, Humberto; Velcheti, Vamsidhar; Madabhushi, Anant (2021). A prognostic and predictive computational pathology image signature for added benefit of adjuvant chemotherapy in early stage non-small-cell lung cancer. EBioMedicine, 69(103481), p. 103481. Elsevier 10.1016/j.ebiom.2021.103481
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Lu, Cheng; Bera, Kaustav; Wang, Xiangxue; Prasanna, Prateek; Xu, Jun; Janowczyk, Andrew; Beig, Niha; Yang, Michael; Fu, Pingfu; Lewis, James; Choi, Humberto; Schmid, Ralph; Berezowska, Sabina; Schalper, Kurt; Rimm, David; Velcheti, Vamsidhar; Madabhushi, Anant (2020). A prognostic model for overall survival of patients with early-stage non-small cell lung cancer: a multicentre, retrospective study. The Lancet. Digital health, 2(11), e594-e606. Elsevier 10.1016/s2589-7500(20)30225-9
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111
Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Bichsel, Colette Andrea; Hall, Sean; Schmid, Ralph; Guenat, Olivier Thierry; Geiser, Thomas (2015). Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. Tissue engineering. Part A, 21(15-16), p. 2166. Mary Ann Liebert 10.1089/ten.TEA.2014.0545
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Blom, Rebecca Agaatha Maria; Amacker, Mario; Moser, Christian; van Dijk, R Maarten; Bonetti, Raffaela; Seydoux, Emilie; Hall, Sean; von Garnier, Christophe; Blank, Fabian (2017). Virosome-bound antigen enhances DC-dependent specific CD4(+) T cell stimulation, inducing a Th1 and Treg profile in vitro. Nanomedicine : nanotechnology, biology, and medicine, 13(5), pp. 1725-1737. Elsevier 10.1016/j.nano.2017.02.004
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Blom, Rebecca Agaatha Maria; Erni, Silvia T; Krempaská, Kristína; Schaerer, Olivier; van Dijk, R Maarten; Amacker, Mario; Moser, Christian; Hall, Sean; Von Garnier, Christophe; Blank, Fabian (2016). A Triple Co-Culture Model of the Human Respiratory Tract to Study Immune-Modulatory Effects of Liposomes and Virosomes. PLoS ONE, 11(9), e0163539. Public Library of Science 10.1371/journal.pone.0163539
Blom, Rebecca Agaatha Maria; Amacker, Mario; Moser, Christian; van Dijk, R Maarten; Bonetti, Raffaela; Seydoux, Emilie; Hall, Sean; von Garnier, Christophe; Blank, Fabian (2017). Virosome-bound antigen enhances DC-dependent specific CD4(+) T cell stimulation, inducing a Th1 and Treg profile in vitro. Nanomedicine : nanotechnology, biology, and medicine, 13(5), pp. 1725-1737. Elsevier 10.1016/j.nano.2017.02.004
Blom, Rebecca Agaatha Maria; Erni, Silvia T; Krempaská, Kristína; Schaerer, Olivier; van Dijk, R Maarten; Amacker, Mario; Moser, Christian; Hall, Sean; Von Garnier, Christophe; Blank, Fabian (2016). A Triple Co-Culture Model of the Human Respiratory Tract to Study Immune-Modulatory Effects of Liposomes and Virosomes. PLoS ONE, 11(9), e0163539. Public Library of Science 10.1371/journal.pone.0163539
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Chrysou, Konstantina; Gioutsos, Konstantinos; Filips, Alexandra; Schmid, Roger; Schmid, Ralph; Kocher, Gregor (2016). Spontaneous right whole-lung torsion secondary to bronchial carcinoma: a case report. Journal of cardiothoracic surgery, 11(107), p. 107. Biomed Central 10.1186/s13019-016-0506-z
Bongoni, Anjan K; Kiermeir, David; Denoyelle, Julie Sophie Cécile; Jenni, Hansjörg; Burlak, Christopher; Seebach, Jörg D; Vögelin, Esther; Constantinescu, Mihai Adrian; Rieben, Robert (2015). Porcine extrahepatic vascular endothelial asialoglycoprotein receptor 1 mediates xenogeneic platelet phagocytosis in vitro and in human-to-pig ex vivo xenoperfusion. Transplantation, 99(4), pp. 693-701. Lippincott Williams & Wilkins 10.1097/TP.0000000000000553
Cortes, Lourdes; Froment, Laurène; Kocher, Gregor; Schmid, Ralph (2016). Human lung-derived mesenchymal stem cell-conditioned medium exerts in vitro antitumor effects in malignant pleural mesothelioma cell lines. Stem cell research & therapy, 7(1), p. 25. BioMed Central 10.1186/s13287-016-0282-7
Cortes-Dericks, Lourdes; Froment, Laurène; Boesch, Ruben; Schmid, Ralph; Karoubi, Golnaz (2014). Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity. BMC cancer, 14, p. 304. BioMed Central 10.1186/1471-2407-14-304
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Cortes-Dericks, Lourdes; Yazd, Ehsan Farashahi; Mowla, Seyed J.; Schmid, Ralph A.; Karoubi, Golnaz (2013). Suppression of OCT4B enhances sensitivity of lung adenocarcinoma A549 cells to cisplatin via increased apoptosis. Anticancer research, 33(12), pp. 5365-5373. International Inst. of Anticancer Research
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Ma, Andi; Sun, Yukai; Ogbodu, Racheal O; Xiao, Ling; Deng, Haibin; Zhou, Hui (2023). Identification of biomarkers of hepatocellular carcinoma gene prognosis based on the immune-related lncRNA signature of transcriptome data. Functional & integrative genomics, 23(2), p. 104. Springer 10.1007/s10142-023-01019-x
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Bongoni, Anjan K; Kiermeir, David; Denoyelle, Julie Sophie Cécile; Jenni, Hansjörg; Burlak, Christopher; Seebach, Jörg D; Vögelin, Esther; Constantinescu, Mihai Adrian; Rieben, Robert (2015). Porcine extrahepatic vascular endothelial asialoglycoprotein receptor 1 mediates xenogeneic platelet phagocytosis in vitro and in human-to-pig ex vivo xenoperfusion. Transplantation, 99(4), pp. 693-701. Lippincott Williams & Wilkins 10.1097/TP.0000000000000553
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Xu, Duo; Liu, Shengchen; Wu, Xi; Marti, Thomas M; Dorn, Patrick; Schmid, Ralph A; Peng, Ren-Wang; Shu, Yongqian (2022). Dissecting the Immunological Profiles in NSD3-Amplified LUSC through Integrative Multi-Scale Analyses. Cancers, 14(20) MDPI AG 10.3390/cancers14204997
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Gao, Yanyun; Kruithof-de Julio, Marianna; Peng, Ren-Wang; Dorn, Patrick (2022). Organoids as a Model for Precision Medicine in Malignant Pleural Mesothelioma: Where Are We Today? Cancers, 14(15) MDPI AG 10.3390/cancers14153758
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Ning, Wenjuan; Yang, Zhang; Kocher, Gregor J; Dorn, Patrick; Peng, Ren-Wang (2022). A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished. Cancers, 14(2) MDPI AG 10.3390/cancers14020390
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Ning, Wenjuan; Marti, Thomas M; Dorn, Patrick; Peng, Ren-Wang (2022). Non-genetic adaptive resistance to KRASG12C inhibition: EMT is not the only culprit. Frontiers in oncology, 12, p. 1004669. Frontiers Research Foundation 10.3389/fonc.2022.1004669
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Azenha, Luis Filipe; Deckarm, Robin; Minervini, Fabrizio; Dorn, Patrick; Lutz, Jon; Kocher, Gregor Jan (2021). Robotic vs. Transsternal Thymectomy: A Single Center Experience over 10 Years. Journal of clinical medicine, 10(21) MDPI 10.3390/jcm10214991
Zehnder, Adrian; Lutz, Jon; Dorn, Patrick; Minervini, Fabrizio; Kestenholz, Peter; Gelpke, Hans; Schmid, Ralph A.; Kocher, Gregor J. (2021). Robotic-Assisted Thoracoscopic Resection of the First Rib for Vascular Thoracic Outlet Syndrome: The New Gold Standard of Treatment? Journal of clinical medicine, 10(17) MDPI 10.3390/jcm10173952
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Kocher, Gregor; Al-Hurani, Mohammad; Dorn, Patrick; Lutz, Jon (2020). Thoracoscopic diaphragm plication. Multimedia Manual of Cardiothoracic Surgery, 2020 Oxford University Press 10.1510/mmcts.2020.054
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Schmidt Leuenberger, Joachim M; Hoksch, Beatrix; Luder, Gere; Schmid, Ralph A.; Verra, Martin L.; Dorn, Patrick (2019). Early Assessment and Management of Dysphagia After Lung Resection: A Randomized Controlled Trial. The Annals of Thoracic Surgery, 108(4), pp. 1059-1064. Elsevier 10.1016/j.athoracsur.2019.04.067
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Bibby, Anna C; Dorn, Patrick; Psallidas, Ioannis; Porcel, Jose M; Janssen, Julius; Froudarakis, Marios; Subotic, Dragan; Astoul, Phillippe; Licht, Peter; Schmid, Ralph; Scherpereel, Arnaud; Rahman, Najib M; Maskell, Nick A; Cardillo, Giuseppe (2019). ERS/EACTS statement on the management of malignant pleural effusions. European journal of cardio-thoracic surgery, 55(1), pp. 116-132. Oxford University Press 10.1093/ejcts/ezy258
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Plourde, Madelaine; Jad, Ahmed; Dorn, Patrick; Harris, Kyla; Mujoomdar, Aneil; Henteleff, Harry; French, Daniel; Bethune, Drew (2018). Digital Air Leak Monitoring for Lung Resection Patients: A Randomized Controlled Clinical Trial. The Annals of Thoracic Surgery, 106(6), pp. 1628-1632. Elsevier 10.1016/j.athoracsur.2018.06.080
Bibby, Anna C; Dorn, Patrick; Psallidas, Ioannis; Porcel, Jose M; Janssen, Julius; Froudarakis, Marios; Subotic, Dragan; Astoul, Phillippe; Licht, Peter; Schmid, Ralph; Scherpereel, Arnaud; Rahman, Najib M; Cardillo, Giuseppe; Maskell, Nick A (2018). ERS/EACTS statement on the management of malignant pleural effusions. European respiratory journal, 52(1) European Respiratory Society 10.1183/13993003.00349-2018
Dorn, Patrick; Veronesi, Giulia; Dunning, Joel; Cardillo, Giuseppe; Schmid, Ralph; Collins, Justin; Baste, Jean-Marc; Limmer, Stefan; Shahin, Ghada M M; Egberts, Jan-Hendrik; Pardolesi, Alessandro; Meacci, Elisa; Stamenkovic, Sasha; Casali, Gianluca; Rueckert, Jens C; Taurchini, Mauro; Santelmo, Nicola; Melfi, Franca; Toker, Alper (2018). Outcomes from the Delphi process of the Thoracic Robotic Curriculum Development Committee. European journal of cardio-thoracic surgery, 53(6), pp. 1173-1179. Oxford University Press 10.1093/ejcts/ezx466
Lutz, Jon Andri; Dorn, Patrick; Schmid, Ralph; Kocher, Gregor (2018). Upper lobe anterior segment (S3): technique of fissureless uniportal VATS segmentectomy. Journal of thoracic disease, 10(6), pp. 3797-3799. AME Publishing Company 10.21037/jtd.2018.05.88
Dorn, Patrick; Kuhn, Michael A; Schweizer, Barbara A; Schmid, Ralph; Kocher, Gregor (2018). Xiphoidectomy for Intractable Xiphodynia. World journal of surgery, 42(11), pp. 3646-3650. Springer-Verlag 10.1007/s00268-018-4668-9
Kocher, Gregor; Gioutsos, Konstantinos; Ahler, Markus; Funke-Chambour, Manuela; Ott, Sebastian Robert; Dorn, Patrick; Lutz, Jon Andri; Schmid, Ralph (2017). Perioperative Lung Function Monitoring for Anatomic Lung Resections. The Annals of Thoracic Surgery, 104(5), pp. 1725-1732. Elsevier 10.1016/j.athoracsur.2017.06.018
Kocher, Gregor; Dorn, Patrick (2017). Minimally invasive resection and reconstruction of the intrathoracic trachea and carina. Journal of thoracic disease, 9(11), pp. 4319-4322. Pioneer Bioscience Publishing 10.21037/jtd.2017.10.04
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Marti, Thomas; Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph (2016). 23P Prolonged pemetrexed pretreatment increases efficiency of ionizing radiation combination therapy and correlates with the persistence of treatment-induced DNA damage in lung cancer cells. Journal of thoracic oncology, 11(4Suppl), S65-S65. Elsevier 10.1016/S1556-0864(16)30137-X
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph (2016). 22P Increased schedule-dependent efficiency of pemetrexed-cisplatin combination therapy eliminates resistant lung cancer stem-like cells associated with EMT. Journal of thoracic oncology, 11(4Suppl), S64-S65. Elsevier 10.1016/S1556-0864(16)30136-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. BMC cancer, 16(125), p. 125. BioMed Central 10.1186/s12885-016-2117-4
Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells. Cancer cell international, 16(66), p. 66. BioMed Central 10.1186/s12935-016-0346-x
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Glatzer, Markus; Leskow, Pawel; Caparrotti, Francesca; Elicin, Olgun; Furrer, Markus; Gambazzi, Franco; Dutly, André; Gelpke, Hans; Guckenberger, Matthias; Heuberger, Jürg; Inderbitzi, Rolf; Cafarotti, Stefano; Karenovics, Wolfram; Kestenholz, Peter; Kocher, Gregor; Kraxner, Peter; Krueger, Thorsten; Martucci, Francesco; Oehler, Christoph; Ozsahin, Mahmut; ... (2021). Stage III N2 non-small cell lung cancer treatment: decision-making among surgeons and radiation oncologists. Translational lung cancer research, 10(4), pp. 1960-1968. AME Publishing 10.21037/tlcr-20-1210
Tièche, Colin Charles; Schmid, Ralph A. (2017). Discovery and characterization of plastic subpopulations associated with distinct hallmarks of cancer in the NSCLC cell line A549. (Dissertation, Graduate School for Cellular and Biomedical Sciences)
Kocher, Gregor; Zehnder, Adrian; Erdös, Gabor; Seidl, Christian Andreas; Winkler, Bernhard; Schmid, Ralph (2017). Single-cannula, single-incision thoracoscopic anatomic segmentectomy after pneumonectomy. Journal of thoracic and cardiovascular surgery, 154(2), e29-e31. Mosby 10.1016/j.jtcvs.2017.03.127
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Kocher, Gregor; Deckarm, Sarah; Flury, Dominik Valentin (2023). Completely portal robotic Pancoast tumour resection with en bloc resection of the left upper lobe and chest wall. Multimedia Manual of Cardiothoracic Surgery, 2023 The European Association for Cardio-Thoracic Surgery (EACTS) 10.1510/mmcts.2023.072
Taha, Anas; Flury, Dominik Valentin; Enodien, Bassey; Taha-Mehlitz, Stephanie; Schmid, Ralph (2022). The development of machine learning in lung surgery: A narrative review. Frontiers in Surgery, 9, p. 914903. Frontiers 10.3389/fsurg.2022.914903
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Keil, Andreas; Hall, Sean; Körner, Meike; Herrmann, Martin; Schmid, Ralph; Frese, Steffen R. (2016). Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan. Arthritis research & therapy, 18(243), p. 243. BioMed Central 10.1186/s13075-016-1144-5
Keil, Andreas; Frese-Schaper, Manuela; Steiner, Selina; Körner, Meike; Schmid, Ralph; Frese, Steffen R. (2015). The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis. Arthritis & rheumatology, 67(7), pp. 1858-1867. Wiley-Blackwell 10.1002/art.39119
Frese-Schaper, Manuela; Keil, Andreas; Steiner, Selina; Gugger, Mathias; Körner, Meike; Kocher, Gregor; Schiffer, Lena; Anders, Hans-Joachim; Huynh-Do, Uyen; Schmid, Ralph; Frese, Steffen R. (2014). Low dose irinotecan improves advanced lupus nephritis in mice potentially by changing DNA relaxation and anti–double-stranded DNA binding. Arthritis & rheumatology, 66(8), pp. 2259-2269. Wiley-Blackwell 10.1002/art.38665
Frese-Schaper, Manuela; Keil, Andreas; Yagita, Hideo; Steiner, Selina; Falk, Werner; Schmid, Ralph; Frese, Steffen R. (2014). Influence of natural killer cells and perforin-mediated cytolysis on the development of chemically induced lung cancer in A/J mice. Cancer immunology, immunotherapy, 63(6), pp. 571-580. Springer 10.1007/s00262-014-1535-x
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Keil, Andreas; Frese-Schaper, Manuela; Steiner, Selina; Körner, Meike; Schmid, Ralph; Frese, Steffen R. (2015). The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis. Arthritis & rheumatology, 67(7), pp. 1858-1867. Wiley-Blackwell 10.1002/art.39119
Frese-Schaper, Manuela; Keil, Andreas; Steiner, Selina; Gugger, Mathias; Körner, Meike; Kocher, Gregor; Schiffer, Lena; Anders, Hans-Joachim; Huynh-Do, Uyen; Schmid, Ralph; Frese, Steffen R. (2014). Low dose irinotecan improves advanced lupus nephritis in mice potentially by changing DNA relaxation and anti–double-stranded DNA binding. Arthritis & rheumatology, 66(8), pp. 2259-2269. Wiley-Blackwell 10.1002/art.38665
Frese-Schaper, Manuela; Keil, Andreas; Yagita, Hideo; Steiner, Selina; Falk, Werner; Schmid, Ralph; Frese, Steffen R. (2014). Influence of natural killer cells and perforin-mediated cytolysis on the development of chemically induced lung cancer in A/J mice. Cancer immunology, immunotherapy, 63(6), pp. 571-580. Springer 10.1007/s00262-014-1535-x
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Marti, Thomas; Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph (2016). 23P Prolonged pemetrexed pretreatment increases efficiency of ionizing radiation combination therapy and correlates with the persistence of treatment-induced DNA damage in lung cancer cells. Journal of thoracic oncology, 11(4Suppl), S65-S65. Elsevier 10.1016/S1556-0864(16)30137-X
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph (2016). 22P Increased schedule-dependent efficiency of pemetrexed-cisplatin combination therapy eliminates resistant lung cancer stem-like cells associated with EMT. Journal of thoracic oncology, 11(4Suppl), S64-S65. Elsevier 10.1016/S1556-0864(16)30136-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. BMC cancer, 16(125), p. 125. BioMed Central 10.1186/s12885-016-2117-4
Cortes, Lourdes; Froment, Laurène; Kocher, Gregor; Schmid, Ralph (2016). Human lung-derived mesenchymal stem cell-conditioned medium exerts in vitro antitumor effects in malignant pleural mesothelioma cell lines. Stem cell research & therapy, 7(1), p. 25. BioMed Central 10.1186/s13287-016-0282-7
Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells. Cancer cell international, 16(66), p. 66. BioMed Central 10.1186/s12935-016-0346-x
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Cortes-Dericks, Lourdes; Froment, Laurène; Boesch, Ruben; Schmid, Ralph; Karoubi, Golnaz (2014). Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity. BMC cancer, 14, p. 304. BioMed Central 10.1186/1471-2407-14-304
Früh, Martin; Betticher, Daniel C; Stupp, Roger; Xyrafas, Alexandros; Peters, Solange; Ris, Hans Beat; Mirimanoff, Rene Olivier; Ochsenbein, Adrian F.; Schmid, Ralph; Matzinger, Oscar; Stahel, Rolf A; Weder, Walter; Guckenberger, Matthias; Rothschild, Sacha I; Lardinois, Didier; Mach, Nicholas; Mark, Michael; Gautschi, Oliver; Thierstein, Sandra; Biaggi Rudolf, Christine; ... (2019). Multimodal Treatment in Operable Stage III NSCLC: A Pooled Analysis on Long-Term Results of Three SAKK trials (SAKK 16/96, 16/00, and 16/01). Journal of thoracic oncology, 14(1), pp. 115-123. Elsevier 10.1016/j.jtho.2018.09.011
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Guler, Sabina A; Machahua, Carlos; Geiser, Thomas K; Kocher, Gregor; Marti, Thomas M; Tan, Benjamin; Trappetti, Verdiana; Ryerson, Christopher J; Funke-Chambour, Manuela (2022). Dehydroepiandrosterone in fibrotic interstitial lung disease: a translational study. Respiratory research, 23(1), p. 149. BioMed Central 10.1186/s12931-022-02076-9
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Kocher, Gregor; Gioutsos, Konstantinos; Ahler, Markus; Funke-Chambour, Manuela; Ott, Sebastian Robert; Dorn, Patrick; Lutz, Jon Andri; Schmid, Ralph (2017). Perioperative Lung Function Monitoring for Anatomic Lung Resections. The Annals of Thoracic Surgery, 104(5), pp. 1725-1732. Elsevier 10.1016/j.athoracsur.2017.06.018
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
Gao, Yanyun; Kruithof-de Julio, Marianna; Peng, Ren-Wang; Dorn, Patrick (2022). Organoids as a Model for Precision Medicine in Malignant Pleural Mesothelioma: Where Are We Today? Cancers, 14(15) MDPI AG 10.3390/cancers14153758
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Yang, Haitang; Hall, Sean; Sun, Beibei; Zhao, Liang; Gao, Yanyun; Schmid, Ralph A.; Tan, Swee T; Peng, Ren-Wang; Yao, Feng (2021). NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma. Cancers, 13(7) 10.3390/cancers13071561
Yang, Haitang; Zhao, Liang; Gao, Yanyun; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer. Cancers, 12(11) MDPI AG 10.3390/cancers12113273
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph; Peng, Ren-Wang (2020). Oncolytic Viral Therapy for Malignant Pleural Mesothelioma. Journal of thoracic oncology, 15(7), e111-e113. Elsevier 10.1016/j.jtho.2020.03.007
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph A.; Peng, Ren-Wang (2020). The Association of BAP1 Loss-of-Function With the Defect in Homologous Recombination Repair and Sensitivity to PARP-Targeted Therapy. Journal of thoracic oncology, 15(6), e88-e90. Elsevier 10.1016/j.jtho.2020.02.028
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Jafari, Morteza; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Schmid, Ralph; Geiser, Thomas; Gazdhar, Amiq; Hunger, Robert (2018). Efficacy of In Vivo Electroporation-Mediated IL-10 Gene Delivery on Survival of Skin Flaps. The Journal of Membrane Biology, 251(2), pp. 211-219. Springer 10.1007/s00232-017-9974-x
Pierog, Jaroslaw Stanislaw; Tamò, Luca Giuseppe Athos; Fakin, Richard; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Geiser, Thomas; Gazdhar, Amiq; Schmid, Ralph (2018). Bone marrow stem cells modified with human interleukin 10 attenuate acute rejection in rat lung allotransplantation. European journal of cardio-thoracic surgery, 53(1), pp. 194-200. Oxford University Press 10.1093/ejcts/ezx257
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Guler, Sabina A; Machahua, Carlos; Geiser, Thomas K; Kocher, Gregor; Marti, Thomas M; Tan, Benjamin; Trappetti, Verdiana; Ryerson, Christopher J; Funke-Chambour, Manuela (2022). Dehydroepiandrosterone in fibrotic interstitial lung disease: a translational study. Respiratory research, 23(1), p. 149. BioMed Central 10.1186/s12931-022-02076-9
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Jafari, Morteza; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Schmid, Ralph; Geiser, Thomas; Gazdhar, Amiq; Hunger, Robert (2018). Efficacy of In Vivo Electroporation-Mediated IL-10 Gene Delivery on Survival of Skin Flaps. The Journal of Membrane Biology, 251(2), pp. 211-219. Springer 10.1007/s00232-017-9974-x
Pierog, Jaroslaw Stanislaw; Tamò, Luca Giuseppe Athos; Fakin, Richard; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Geiser, Thomas; Gazdhar, Amiq; Schmid, Ralph (2018). Bone marrow stem cells modified with human interleukin 10 attenuate acute rejection in rat lung allotransplantation. European journal of cardio-thoracic surgery, 53(1), pp. 194-200. Oxford University Press 10.1093/ejcts/ezx257
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Bichsel, Colette Andrea; Hall, Sean; Schmid, Ralph; Guenat, Olivier Thierry; Geiser, Thomas (2015). Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. Tissue engineering. Part A, 21(15-16), p. 2166. Mary Ann Liebert 10.1089/ten.TEA.2014.0545
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Ruppen, Janine; Wildhaber, Franziska Daniela; Strub, Christoph; Hall, Sean; Geiser, Thomas; Schmid, Ralph; Guenat, Olivier Thierry (2015). Towards personalized medicine: Chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform. Lab on a chip, 15(14), pp. 3076-3085. Royal Society of Chemistry 10.1039/C5LC00454C
Spycher, Franziska; Kocher, Gregor; Gugger, Mathias; Geiser, Thomas; Ott, Sebastian Robert (2014). Pulmonary aspergilloma: A rare differential diagnosis to lung cancer after positive FDG PET scan. Respiratory Medicine Case Reports, 12, pp. 1-3. Elsevier 10.1016/j.rmcr.2014.02.003
Kocher, Gregor; Gioutsos, Konstantinos (2018). The role of handheld spirometry in lung surgery. Journal of thoracic disease, 10(Suppl 33), S3954-S3956. Pioneer Bioscience Publishing 10.21037/jtd.2018.09.68
Kocher, Gregor; Gioutsos, Konstantinos; Ahler, Markus; Funke-Chambour, Manuela; Ott, Sebastian Robert; Dorn, Patrick; Lutz, Jon Andri; Schmid, Ralph (2017). Perioperative Lung Function Monitoring for Anatomic Lung Resections. The Annals of Thoracic Surgery, 104(5), pp. 1725-1732. Elsevier 10.1016/j.athoracsur.2017.06.018
Adamcik, Stefan; Ahler, Markus; Gioutsos, Konstantinos; Schmid, Ralph; Kocher, Gregor (2017). Repair of sternoclavicular joint dislocations with FiberWire®. Archives of orthopaedic and trauma surgery, 137(3), pp. 341-345. Springer 10.1007/s00402-017-2632-z
Gioutsos, Konstantinos; Kocher, Gregor; Schmid, Ralph (2016). Robotics in pulmonology and thoracic surgery: what, why and when? Panminerva medica, 58(4), pp. 318-328. Edizioni Minerva Medica
Chrysou, Konstantina; Gioutsos, Konstantinos; Filips, Alexandra; Schmid, Roger; Schmid, Ralph; Kocher, Gregor (2016). Spontaneous right whole-lung torsion secondary to bronchial carcinoma: a case report. Journal of cardiothoracic surgery, 11(107), p. 107. Biomed Central 10.1186/s13019-016-0506-z
Glatzer, Markus; Leskow, Pawel; Caparrotti, Francesca; Elicin, Olgun; Furrer, Markus; Gambazzi, Franco; Dutly, André; Gelpke, Hans; Guckenberger, Matthias; Heuberger, Jürg; Inderbitzi, Rolf; Cafarotti, Stefano; Karenovics, Wolfram; Kestenholz, Peter; Kocher, Gregor; Kraxner, Peter; Krueger, Thorsten; Martucci, Francesco; Oehler, Christoph; Ozsahin, Mahmut; ... (2021). Stage III N2 non-small cell lung cancer treatment: decision-making among surgeons and radiation oncologists. Translational lung cancer research, 10(4), pp. 1960-1968. AME Publishing 10.21037/tlcr-20-1210
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Bichsel, Colette Andrea; Hall, Sean; Schmid, Ralph; Guenat, Olivier Thierry; Geiser, Thomas (2015). Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. Tissue engineering. Part A, 21(15-16), p. 2166. Mary Ann Liebert 10.1089/ten.TEA.2014.0545
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Ruppen, Janine; Wildhaber, Franziska Daniela; Strub, Christoph; Hall, Sean; Geiser, Thomas; Schmid, Ralph; Guenat, Olivier Thierry (2015). Towards personalized medicine: Chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform. Lab on a chip, 15(14), pp. 3076-3085. Royal Society of Chemistry 10.1039/C5LC00454C
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Guler, Sabina A; Machahua, Carlos; Geiser, Thomas K; Kocher, Gregor; Marti, Thomas M; Tan, Benjamin; Trappetti, Verdiana; Ryerson, Christopher J; Funke-Chambour, Manuela (2022). Dehydroepiandrosterone in fibrotic interstitial lung disease: a translational study. Respiratory research, 23(1), p. 149. BioMed Central 10.1186/s12931-022-02076-9
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Yang, Haitang; Ma, Wenyan; Sun, Beibei; Fan, Liwen; Xu, Ke; Hall, Sean; Al-Hurani, Mohammad; Schmid, Ralph A.; Peng, Ren-Wang; Hida, Toyoaki; Wang, Zhexin; Yao, Feng (2021). Smoking signature is superior to programmed death-ligand 1 expression in predicting pathological response to neoadjuvant immunotherapy in lung cancer patients. Translational lung cancer research, 10(9), pp. 3807-3822. AME Publishing 10.21037/tlcr-21-734
Yang, Haitang; Sun, Beibei; Xu, Ke; He, Yunfei; Zhang, Tuo; Hall, Sean; Tan, Swee T; Schmid, Ralph A.; Peng, Ren-Wang; Hu, Guohong; Yao, Feng (2021). Pharmaco-transcriptomic correlation analysis reveals novel responsive signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer. EBioMedicine, 69(103457), p. 103457. Elsevier 10.1016/j.ebiom.2021.103457
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Yang, Haitang; Hall, Sean; Sun, Beibei; Zhao, Liang; Gao, Yanyun; Schmid, Ralph A.; Tan, Swee T; Peng, Ren-Wang; Yao, Feng (2021). NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma. Cancers, 13(7) 10.3390/cancers13071561
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Verstegen, Monique M A; Mezzanotte, Laura; Ridwan, R Yanto; Wang, Kairong; de Haan, Jubi; Schurink, Ivo J; Sierra Parraga, Jésus M; Hoogduijn, Martin; Kessler, Benedikt M; Huang, Honglei; Hall, Sean R. R.; IJzermans, Jan N M; Löwik, Clemens W G M; van der Laan, Luc J W; de Jonge, Jeroen (2019). First Report on Ex vivo Delivery of Paracrine Active Human Mesenchymal Stromal Cells to Liver Grafts During Machine Perfusion. Transplantation, 104(1), e5-e7. Lippincott Williams & Wilkins 10.1097/TP.0000000000002986
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111
Blom, Rebecca Agaatha Maria; Amacker, Mario; Moser, Christian; van Dijk, R Maarten; Bonetti, Raffaela; Seydoux, Emilie; Hall, Sean; von Garnier, Christophe; Blank, Fabian (2017). Virosome-bound antigen enhances DC-dependent specific CD4(+) T cell stimulation, inducing a Th1 and Treg profile in vitro. Nanomedicine : nanotechnology, biology, and medicine, 13(5), pp. 1725-1737. Elsevier 10.1016/j.nano.2017.02.004
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Tsoyi, Konstantin; Hall, Sean; Dalli, Jesmond; Colas, Romain A; Ghanta, Sailaja; Ith, Bonna; Coronata, Anna; Fredenburgh, Laura E; Baron, Rebecca M; Choi, Augustine M K; Serhan, Charles N; Liu, Xiaoli; Perrella, Mark A (2016). Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators. Critical care medicine, 44(12), e1236-e1245. Lippincott Williams & Wilkins 10.1097/CCM.0000000000001999
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Keil, Andreas; Hall, Sean; Körner, Meike; Herrmann, Martin; Schmid, Ralph; Frese, Steffen R. (2016). Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan. Arthritis research & therapy, 18(243), p. 243. BioMed Central 10.1186/s13075-016-1144-5
Blom, Rebecca Agaatha Maria; Erni, Silvia T; Krempaská, Kristína; Schaerer, Olivier; van Dijk, R Maarten; Amacker, Mario; Moser, Christian; Hall, Sean; Von Garnier, Christophe; Blank, Fabian (2016). A Triple Co-Culture Model of the Human Respiratory Tract to Study Immune-Modulatory Effects of Liposomes and Virosomes. PLoS ONE, 11(9), e0163539. Public Library of Science 10.1371/journal.pone.0163539
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
de Mare-Bredemeijer, Emmy L D; Mancham, Shanta; Verstegen, Monique M A; de Ruiter, Petra E; van Gent, Rogier; O'Neill, David; Tilanus, Hugo W; Metselaar, Herold J; de Jonge, Jeroen; Kwekkeboom, Jaap; Hall, Sean; van der Laan, Luc J W (2015). Human graft-derived mesenchymal stromal cells potently suppress alloreactive T-cell responses. Stem cells and development, 24(12), pp. 1436-1447. Mary Ann Liebert 10.1089/scd.2014.0485
Bichsel, Colette Andrea; Hall, Sean; Schmid, Ralph; Guenat, Olivier Thierry; Geiser, Thomas (2015). Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. Tissue engineering. Part A, 21(15-16), p. 2166. Mary Ann Liebert 10.1089/ten.TEA.2014.0545
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Ruppen, Janine; Wildhaber, Franziska Daniela; Strub, Christoph; Hall, Sean; Geiser, Thomas; Schmid, Ralph; Guenat, Olivier Thierry (2015). Towards personalized medicine: Chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform. Lab on a chip, 15(14), pp. 3076-3085. Royal Society of Chemistry 10.1039/C5LC00454C
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Hall, Sean R. R.; Jiang, Yajuan; Leary, Elizabeth; Yavanian, Greg; Eminli, Sarah; O'Neill, David W.; Marasco, Wayne A. (2013). Identification and isolation of small CD44-negative mesenchymal stem/progenitor cells from human bone marrow using elutriation and polychromatic flow cytometry. Stem cells translational medicine, 2(8), pp. 567-578. AlphaMed Press 10.5966/sctm.2012-0155
Hall, Sean R. R.; Pedroza-Gonzalez, Alexander; Pan, Qiuwei; Tilanus, Hugo W.; de Jonge, Jeroen; Wagemaker, Gerard; van der Laan, Luc J. W. (2013). Overestimation of hematopoietic stem cell frequencies in human liver grafts. Hepatology, 57(6), pp. 2547-2549. Wiley Interscience 10.1002/hep.26119
Hall, Sean R. R.; Tsoyi, Konstantin; Ith, Bonna; Padera Jr., Robert F.; Lederer, James A.; Wang, Zhihong; Liu, Xiaoli; Perrella, Mark A. (2013). Mesenchymal stromal cells improve survival during sepsis in the absence of heme oxygenase-1: the importance of neutrophils. Stem cells, 31(2), pp. 397-407. AlphaMed Press 10.1002/stem.1270
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Schmidt Leuenberger, Joachim M; Hoksch, Beatrix; Luder, Gere; Schmid, Ralph A.; Verra, Martin L.; Dorn, Patrick (2019). Early Assessment and Management of Dysphagia After Lung Resection: A Randomized Controlled Trial. The Annals of Thoracic Surgery, 108(4), pp. 1059-1064. Elsevier 10.1016/j.athoracsur.2019.04.067
Halat, Gabriel; Negrin, Lukas L; Chrysou, Konstantina; Hoksch, Beatrix; Schmid, Ralph; Kocher, Gregor (2017). Treatment of air leak in polytrauma patients with blunt chest injury. Injury - international journal of the care of the injured, 48(9), pp. 1895-1899. Elsevier 10.1016/j.injury.2017.04.061
Chrysou, Konstantina; Halat, Gabriel; Hoksch, Beatrix; Schmid, Ralph; Kocher, Gregor (2017). Lessons from a large trauma center: impact of blunt chest trauma in polytrauma patients-still a relevant problem? Scandinavian journal of trauma, resuscitation and emergency medicine, 25(1), p. 42. BioMed Central 10.1186/s13049-017-0384-y
BG, Gorensek; Schmid, Ralph; Hoksch, Beatrix (2017). Management of Pleural Effusion by Combining Talc Poudrage and Indwelling Pleural Catheter: A Retrospective Single Center Study. Journal of clinical trials, 07(01) OMICS International 10.4172/2167-0870.1000297
Hoksch, Beatrix; Kocher, Gregor; Vollmar, Philippe Bernard; Praz, Fabien; Schmid, Ralph (2016). Nuss procedure for pectus excavatum in adults: long-term results in a prospective observational study. European journal of cardio-thoracic surgery, 50(5), pp. 934-939. Oxford University Press 10.1093/ejcts/ezw130
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Jafari, Morteza; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Schmid, Ralph; Geiser, Thomas; Gazdhar, Amiq; Hunger, Robert (2018). Efficacy of In Vivo Electroporation-Mediated IL-10 Gene Delivery on Survival of Skin Flaps. The Journal of Membrane Biology, 251(2), pp. 211-219. Springer 10.1007/s00232-017-9974-x
Frese-Schaper, Manuela; Keil, Andreas; Steiner, Selina; Gugger, Mathias; Körner, Meike; Kocher, Gregor; Schiffer, Lena; Anders, Hans-Joachim; Huynh-Do, Uyen; Schmid, Ralph; Frese, Steffen R. (2014). Low dose irinotecan improves advanced lupus nephritis in mice potentially by changing DNA relaxation and anti–double-stranded DNA binding. Arthritis & rheumatology, 66(8), pp. 2259-2269. Wiley-Blackwell 10.1002/art.38665
Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Scholl, Heiko; Lutz, Jon Andri; Kadner, Alexander; Schmid, Ralph (2019). Dynamic stenosis of the right main bronchus in a 3-month-old child: a tracheobronchial sleeve resection under venovenous extracorporeal membrane oxygenation. European journal of cardio-thoracic surgery, 55(3), pp. 579-581. Oxford University Press 10.1093/ejcts/ezy256
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Cortes-Dericks, Lourdes; Froment, Laurène; Boesch, Ruben; Schmid, Ralph; Karoubi, Golnaz (2014). Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity. BMC cancer, 14, p. 304. BioMed Central 10.1186/1471-2407-14-304
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Cortes-Dericks, Lourdes; Yazd, Ehsan Farashahi; Mowla, Seyed J.; Schmid, Ralph A.; Karoubi, Golnaz (2013). Suppression of OCT4B enhances sensitivity of lung adenocarcinoma A549 cells to cisplatin via increased apoptosis. Anticancer research, 33(12), pp. 5365-5373. International Inst. of Anticancer Research
Keil, Andreas; Hall, Sean; Körner, Meike; Herrmann, Martin; Schmid, Ralph; Frese, Steffen R. (2016). Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan. Arthritis research & therapy, 18(243), p. 243. BioMed Central 10.1186/s13075-016-1144-5
Keil, Andreas; Frese-Schaper, Manuela; Steiner, Selina; Körner, Meike; Schmid, Ralph; Frese, Steffen R. (2015). The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis. Arthritis & rheumatology, 67(7), pp. 1858-1867. Wiley-Blackwell 10.1002/art.39119
Frese-Schaper, Manuela; Keil, Andreas; Steiner, Selina; Gugger, Mathias; Körner, Meike; Kocher, Gregor; Schiffer, Lena; Anders, Hans-Joachim; Huynh-Do, Uyen; Schmid, Ralph; Frese, Steffen R. (2014). Low dose irinotecan improves advanced lupus nephritis in mice potentially by changing DNA relaxation and anti–double-stranded DNA binding. Arthritis & rheumatology, 66(8), pp. 2259-2269. Wiley-Blackwell 10.1002/art.38665
Frese-Schaper, Manuela; Keil, Andreas; Yagita, Hideo; Steiner, Selina; Falk, Werner; Schmid, Ralph; Frese, Steffen R. (2014). Influence of natural killer cells and perforin-mediated cytolysis on the development of chemically induced lung cancer in A/J mice. Cancer immunology, immunotherapy, 63(6), pp. 571-580. Springer 10.1007/s00262-014-1535-x
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Bongoni, Anjan K; Kiermeir, David; Denoyelle, Julie Sophie Cécile; Jenni, Hansjörg; Burlak, Christopher; Seebach, Jörg D; Vögelin, Esther; Constantinescu, Mihai Adrian; Rieben, Robert (2015). Porcine extrahepatic vascular endothelial asialoglycoprotein receptor 1 mediates xenogeneic platelet phagocytosis in vitro and in human-to-pig ex vivo xenoperfusion. Transplantation, 99(4), pp. 693-701. Lippincott Williams & Wilkins 10.1097/TP.0000000000000553
Kocher, Gregor; Deckarm, Sarah; Flury, Dominik Valentin (2023). Completely portal robotic Pancoast tumour resection with en bloc resection of the left upper lobe and chest wall. Multimedia Manual of Cardiothoracic Surgery, 2023 The European Association for Cardio-Thoracic Surgery (EACTS) 10.1510/mmcts.2023.072
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Guler, Sabina A; Machahua, Carlos; Geiser, Thomas K; Kocher, Gregor; Marti, Thomas M; Tan, Benjamin; Trappetti, Verdiana; Ryerson, Christopher J; Funke-Chambour, Manuela (2022). Dehydroepiandrosterone in fibrotic interstitial lung disease: a translational study. Respiratory research, 23(1), p. 149. BioMed Central 10.1186/s12931-022-02076-9
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Ning, Wenjuan; Yang, Zhang; Kocher, Gregor J; Dorn, Patrick; Peng, Ren-Wang (2022). A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished. Cancers, 14(2) MDPI AG 10.3390/cancers14020390
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Gkikas, Andreas; Lampridis, Savvas; Patrini, Davide; Kestenholz, Peter B; Azenha, Luis Filipe; Kocher, Gregor; Scarci, Marco; Minervini, Fabrizio (2022). Thoracic Outlet Syndrome: Single Center Experience on Robotic Assisted First Rib Resection and Literature Review. Frontiers in Surgery, 9, p. 848972. Frontiers 10.3389/fsurg.2022.848972
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Azenha, Luis Filipe; Deckarm, Robin; Minervini, Fabrizio; Dorn, Patrick; Lutz, Jon; Kocher, Gregor Jan (2021). Robotic vs. Transsternal Thymectomy: A Single Center Experience over 10 Years. Journal of clinical medicine, 10(21) MDPI 10.3390/jcm10214991
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Zehnder, Adrian; Lutz, Jon; Dorn, Patrick; Minervini, Fabrizio; Kestenholz, Peter; Gelpke, Hans; Schmid, Ralph A.; Kocher, Gregor J. (2021). Robotic-Assisted Thoracoscopic Resection of the First Rib for Vascular Thoracic Outlet Syndrome: The New Gold Standard of Treatment? Journal of clinical medicine, 10(17) MDPI 10.3390/jcm10173952
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Glatzer, Markus; Leskow, Pawel; Caparrotti, Francesca; Elicin, Olgun; Furrer, Markus; Gambazzi, Franco; Dutly, André; Gelpke, Hans; Guckenberger, Matthias; Heuberger, Jürg; Inderbitzi, Rolf; Cafarotti, Stefano; Karenovics, Wolfram; Kestenholz, Peter; Kocher, Gregor; Kraxner, Peter; Krueger, Thorsten; Martucci, Francesco; Oehler, Christoph; Ozsahin, Mahmut; ... (2021). Stage III N2 non-small cell lung cancer treatment: decision-making among surgeons and radiation oncologists. Translational lung cancer research, 10(4), pp. 1960-1968. AME Publishing 10.21037/tlcr-20-1210
Rouiller, Benoît; Lutz, Jon A.; Kocher, Gregor J.; Magnusson, Lennart (2020). Bilateral thoracic duct ligation for persisting postoperative chylothorax. Interactive cardiovascular and thoracic surgery, 31(4), pp. 583-584. Oxford University Press 10.1093/icvts/ivaa128
Kocher, Gregor; Al-Hurani, Mohammad; Dorn, Patrick; Lutz, Jon (2020). Thoracoscopic diaphragm plication. Multimedia Manual of Cardiothoracic Surgery, 2020 Oxford University Press 10.1510/mmcts.2020.054
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Haecker, Frank-Martin; Krebs, Thomas; Kocher, Gregor; Schmid, Ralph; Sesia, Sergio Bruno (2019). Sternal elevation techniques during the minimally invasive repair of pectus excavatum. Interactive cardiovascular and thoracic surgery, 29(4), pp. 497-502. Oxford University Press 10.1093/icvts/ivz142
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Kocher, Gregor; Sesia, Sergio Bruno; Lopez-Hilfiker, Felipe; Schmid, Ralph (2019). Surgical smoke: still an underestimated health hazard in the operating theatre. European journal of cardio-thoracic surgery, 55(4), pp. 626-631. Oxford University Press 10.1093/ejcts/ezy356
Kocher, Gregor; Sesia, Sergio Bruno; Lopez-Hilfiker, Felipe; Schmid, Ralph (2019). Corrigendum to 'Surgical smoke: still an underestimated health hazard in the operating theatre' [Eur J Cardiothorac Surg 2019;55:626--631]. European journal of cardio-thoracic surgery, 55(4), p. 803. Oxford University Press 10.1093/ejcts/ezz017
Kocher, Gregor (2019). Multiport and uniportal VATS sleeve resections. Journal of thoracic disease, 11(4), pp. 1091-1093. Pioneer Bioscience Publishing 10.21037/jtd.2019.02.92
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Sesia, Sergio Bruno; Heitzelmann, Margarete; Schaedelin, Sabine; Magerkurth, Olaf; Kocher, Gregor; Schmid, Ralph; Haecker, Frank-Martin (2019). Standardized Haller and Asymmetry Index Combined for a More Accurate Assessment of Pectus Excavatum. The annals of thoracic surgery, 107(1), pp. 271-276. Elsevier 10.1016/j.athoracsur.2018.07.086
Kocher, Gregor; Gioutsos, Konstantinos (2018). The role of handheld spirometry in lung surgery. Journal of thoracic disease, 10(Suppl 33), S3954-S3956. Pioneer Bioscience Publishing 10.21037/jtd.2018.09.68
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmidli, Jürg; Schmid, Ralph (2018). First Rib Resection for Thoracic Outlet Syndrome: The Robotic Approach. World journal of surgery, 42(10), pp. 3250-3255. Springer 10.1007/s00268-018-4636-4
Liu, Lunxu; Mei, Jiandong; He, Jie; Gao, Shugeng; Li, Shanqing; He, Jianxing; Huang, Yunchao; Xu, Shidong; Mao, Weimin; Tan, Qunyou; Chen, Chun; Li, Xiaofei; Zhang, Zhu; Jiang, Gening; Xu, Lin; Zhang, Lanjun; Fu, Jianhua; Li, Hui; Wang, Qun; Liu, Deruo; ... (2018). Society for Translational Medicine expert consensus on training and certification standards for surgeons and assistants in minimally invasive surgery for lung cancer. Journal of thoracic disease, 10(10), pp. 5666-5672. Pioneer Bioscience Publishing 10.21037/jtd.2018.08.72
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Lutz, Jon Andri; Dorn, Patrick; Schmid, Ralph; Kocher, Gregor (2018). Upper lobe anterior segment (S3): technique of fissureless uniportal VATS segmentectomy. Journal of thoracic disease, 10(6), pp. 3797-3799. AME Publishing Company 10.21037/jtd.2018.05.88
Dorn, Patrick; Kuhn, Michael A; Schweizer, Barbara A; Schmid, Ralph; Kocher, Gregor (2018). Xiphoidectomy for Intractable Xiphodynia. World journal of surgery, 42(11), pp. 3646-3650. Springer-Verlag 10.1007/s00268-018-4668-9
Sesia, Sergio Bruno; Heinrich, Daniel M; Kocher, Gregor; Haecker, Frank-Martin (2018). Treatment of isolated sternal fracture with a vacuum bell in an 8-year-old boy. Interactive cardiovascular and thoracic surgery, 26(5), pp. 888-889. Oxford University Press 10.1093/icvts/ivx421
Pierog, Jaroslaw Stanislaw; Tamò, Luca Giuseppe Athos; Fakin, Richard; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Geiser, Thomas; Gazdhar, Amiq; Schmid, Ralph (2018). Bone marrow stem cells modified with human interleukin 10 attenuate acute rejection in rat lung allotransplantation. European journal of cardio-thoracic surgery, 53(1), pp. 194-200. Oxford University Press 10.1093/ejcts/ezx257
Nguyen, Thanh-Long; Schmid, Ralph; Kocher, Gregor (2017). Transmediastinal Left-Sided Video-Assisted Thoracoscopic Lung Volume Reduction Surgery after Right Upper Lobectomy for Destroyed Upper Lobe. Case reports journal, 1(1), 005. The Biomedica
Azenha Figueiredo, Luís Filipe; Schmid, Ralph; Kocher, Gregor (2017). Complex Tracheal Repair after Severe Tracheal Rupture during Percutaneous Dilatational Tracheostomy. Case reports journal, 1(1), 001. The Biomedica
Zehnder, Adrian; Kocher, Gregor; Seitz, Michael; Schmid, Ralph (2017). IgG4-related disease of the lung: a rare differential diagnosis to lung cancer after positive positron emission tomography and biopsy. European journal of cardio-thoracic surgery, 52(5), pp. 1003-1004. Oxford University Press 10.1093/ejcts/ezx265
Kocher, Gregor; Gioutsos, Konstantinos; Ahler, Markus; Funke-Chambour, Manuela; Ott, Sebastian Robert; Dorn, Patrick; Lutz, Jon Andri; Schmid, Ralph (2017). Perioperative Lung Function Monitoring for Anatomic Lung Resections. The Annals of Thoracic Surgery, 104(5), pp. 1725-1732. Elsevier 10.1016/j.athoracsur.2017.06.018
Kocher, Gregor; Dorn, Patrick (2017). Minimally invasive resection and reconstruction of the intrathoracic trachea and carina. Journal of thoracic disease, 9(11), pp. 4319-4322. Pioneer Bioscience Publishing 10.21037/jtd.2017.10.04
Meyring, Kristina; Zehnder, Adrian; Schmid, Ralph; Kocher, Gregor (2017). Thoracic surgery in patients with an implanted neurostimulator device. Interactive cardiovascular and thoracic surgery, 25(4), pp. 667-668. Oxford University Press 10.1093/icvts/ivx213
Halat, Gabriel; Negrin, Lukas L; Chrysou, Konstantina; Hoksch, Beatrix; Schmid, Ralph; Kocher, Gregor (2017). Treatment of air leak in polytrauma patients with blunt chest injury. Injury - international journal of the care of the injured, 48(9), pp. 1895-1899. Elsevier 10.1016/j.injury.2017.04.061
Lutz, Jon Andri; Kocher, Gregor (2017). Technical aspects of video-assisted and robotic-assisted thoracoscopic segmentectomy. Journal of thoracic disease, 9(8), pp. 2320-2322. Pioneer Bioscience Publishing 10.21037/jtd.2017.08.36
Kocher, Gregor (2017). Robotic-assisted thoracoscopic surgery: state of the art and future perspectives. Journal of thoracic disease, 9(7), pp. 1855-1857. Pioneer Bioscience Publishing 10.21037/jtd.2017.06.139
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmid, Ralph (May 2017). Thoracoscopic diaphragmatic plication made easy. British journal of surgery, 104(S4), p. 26. John Wright & Sons
Zehnder, Adrian; Kocher, Gregor; Lutz, Jon Andri; Schmid, Ralph (May 2017). Robotic first rib resection for thoracic outlet syndrome: The DaVinci-assisted minimally invasive approach. British journal of surgery, 104(S4), p. 26. John Wright & Sons
Chrysou, Konstantina; Halat, Gabriel; Hoksch, Beatrix; Schmid, Ralph; Kocher, Gregor (2017). Lessons from a large trauma center: impact of blunt chest trauma in polytrauma patients-still a relevant problem? Scandinavian journal of trauma, resuscitation and emergency medicine, 25(1), p. 42. BioMed Central 10.1186/s13049-017-0384-y
Kocher, Gregor; Zehnder, Adrian; Erdös, Gabor; Seidl, Christian Andreas; Winkler, Bernhard; Schmid, Ralph (2017). Single-cannula, single-incision thoracoscopic anatomic segmentectomy after pneumonectomy. Journal of thoracic and cardiovascular surgery, 154(2), e29-e31. Mosby 10.1016/j.jtcvs.2017.03.127
Kocher, Gregor; Zehnder, Adrian; Schmid, Ralph (2017). Completely Thoracoscopic Diaphragmatic Plication. World journal of surgery, 41(4), pp. 1019-1022. Springer 10.1007/s00268-016-3789-2
Adamcik, Stefan; Ahler, Markus; Gioutsos, Konstantinos; Schmid, Ralph; Kocher, Gregor (2017). Repair of sternoclavicular joint dislocations with FiberWire®. Archives of orthopaedic and trauma surgery, 137(3), pp. 341-345. Springer 10.1007/s00402-017-2632-z
Kocher, Gregor; Abu-Omar, Yasir; Bosco, Paolo; Barbero, Cristina; Waller, David; Gudbjartsson, Tomas; Sousa-Uva, Miguel; Licht, Peter B; Dunning, Joel; Schmid, Ralph; Cardillo, Giuseppe (2017). European Association for Cardio-Thoracic Surgery expert consensus statement on the prevention and management of mediastinitis. European journal of cardio-thoracic surgery, 51(1), pp. 10-29. Oxford University Press 10.1093/ejcts/ezw326
Lutz, Jon Andri; Nguyen, Thanh-Long; Schmid, Ralph; Kocher, Gregor J. (2017). Opening of the horizontal fissure as a key step for (minimally invasive) right S3-Segmentectomy. British journal of surgery, 104(Supplement_4), pp. 5-26. John Wright & Sons 10.1002/bjs.10605
Kocher, Gregor; Sharafi, Siamak; Azenha Figueiredo, Luis Filipe; Schmid, Ralph (2016). Chest wall stabilization in ventilator-dependent traumatic flail chest patients: who benefits? European journal of cardio-thoracic surgery, 51(4), pp. 696-701. Oxford University Press 10.1093/ejcts/ezw365
Gioutsos, Konstantinos; Kocher, Gregor; Schmid, Ralph (2016). Robotics in pulmonology and thoracic surgery: what, why and when? Panminerva medica, 58(4), pp. 318-328. Edizioni Minerva Medica
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Hoksch, Beatrix; Kocher, Gregor; Vollmar, Philippe Bernard; Praz, Fabien; Schmid, Ralph (2016). Nuss procedure for pectus excavatum in adults: long-term results in a prospective observational study. European journal of cardio-thoracic surgery, 50(5), pp. 934-939. Oxford University Press 10.1093/ejcts/ezw130
Kocher, Gregor; Gstrein, Nathalie; Jaroszewski, Dawn E; Ewais, Mennatallah M; Schmid, Ralph (2016). Nuss procedure for repair of pectus excavatum after failed Ravitch procedure in adults: indications and caveats. Journal of thoracic disease, 8(8), pp. 1981-1985. Pioneer Bioscience Publishing 10.21037/jtd.2016.06.60
Chrysou, Konstantina; Gioutsos, Konstantinos; Filips, Alexandra; Schmid, Roger; Schmid, Ralph; Kocher, Gregor (2016). Spontaneous right whole-lung torsion secondary to bronchial carcinoma: a case report. Journal of cardiothoracic surgery, 11(107), p. 107. Biomed Central 10.1186/s13019-016-0506-z
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Cortes, Lourdes; Froment, Laurène; Kocher, Gregor; Schmid, Ralph (2016). Human lung-derived mesenchymal stem cell-conditioned medium exerts in vitro antitumor effects in malignant pleural mesothelioma cell lines. Stem cell research & therapy, 7(1), p. 25. BioMed Central 10.1186/s13287-016-0282-7
Kocher, Gregor; Poulson, Jannie Lysgaard; Blichfeldt-Eckhardt, Morten Rune; Elle, Bo; Schmid, Ralph; Licht, Peter B (2015). The importance of phrenic nerve preservation and its effect on long-term postoperative lung function after pneumonectomy. European journal of cardio-thoracic surgery, 49(4), pp. 1059-1062. Oxford University Press 10.1093/ejcts/ezv334
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Frese-Schaper, Manuela; Keil, Andreas; Steiner, Selina; Gugger, Mathias; Körner, Meike; Kocher, Gregor; Schiffer, Lena; Anders, Hans-Joachim; Huynh-Do, Uyen; Schmid, Ralph; Frese, Steffen R. (2014). Low dose irinotecan improves advanced lupus nephritis in mice potentially by changing DNA relaxation and anti–double-stranded DNA binding. Arthritis & rheumatology, 66(8), pp. 2259-2269. Wiley-Blackwell 10.1002/art.38665
Spycher, Franziska; Kocher, Gregor; Gugger, Mathias; Geiser, Thomas; Ott, Sebastian Robert (2014). Pulmonary aspergilloma: A rare differential diagnosis to lung cancer after positive FDG PET scan. Respiratory Medicine Case Reports, 12, pp. 1-3. Elsevier 10.1016/j.rmcr.2014.02.003
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Gao, Yanyun; Kruithof-de Julio, Marianna; Peng, Ren-Wang; Dorn, Patrick (2022). Organoids as a Model for Precision Medicine in Malignant Pleural Mesothelioma: Where Are We Today? Cancers, 14(15) MDPI AG 10.3390/cancers14153758
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111
Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Zhao, Liang; Li, Shuangjiang; Ju, Juan; Zhou, Haining; Wang, Hongyu; Che, Guowei (2021). Gamma-Glutamyl Transpeptidase to Platelet Ratio Is a Novel and Independent Prognostic Marker for Resectable Lung Cancer: A Propensity Score Matching Study. Annals of thoracic and cardiovascular surgery, 27(3), pp. 151-163. J-STAGE 10.5761/atcs.oa.20-00247
Zhang, Yang; Zhao, Liang; Li, Shuangjiang; Liu, Junhua (2020). Is liposomal bupivacaine superior to standard bupivacaine for pain control following minimally invasive thoracic surgery? Interactive cardiovascular and thoracic surgery, 31(2), pp. 199-203. Oxford University Press 10.1093/icvts/ivaa083
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Azenha, Luis Filipe; Deckarm, Robin; Minervini, Fabrizio; Dorn, Patrick; Lutz, Jon; Kocher, Gregor Jan (2021). Robotic vs. Transsternal Thymectomy: A Single Center Experience over 10 Years. Journal of clinical medicine, 10(21) MDPI 10.3390/jcm10214991
Zehnder, Adrian; Lutz, Jon; Dorn, Patrick; Minervini, Fabrizio; Kestenholz, Peter; Gelpke, Hans; Schmid, Ralph A.; Kocher, Gregor J. (2021). Robotic-Assisted Thoracoscopic Resection of the First Rib for Vascular Thoracic Outlet Syndrome: The New Gold Standard of Treatment? Journal of clinical medicine, 10(17) MDPI 10.3390/jcm10173952
Rouiller, Benoît; Lutz, Jon A.; Kocher, Gregor J.; Magnusson, Lennart (2020). Bilateral thoracic duct ligation for persisting postoperative chylothorax. Interactive cardiovascular and thoracic surgery, 31(4), pp. 583-584. Oxford University Press 10.1093/icvts/ivaa128
Kocher, Gregor; Al-Hurani, Mohammad; Dorn, Patrick; Lutz, Jon (2020). Thoracoscopic diaphragm plication. Multimedia Manual of Cardiothoracic Surgery, 2020 Oxford University Press 10.1510/mmcts.2020.054
Scholl, Heiko; Lutz, Jon Andri; Kadner, Alexander; Schmid, Ralph (2019). Dynamic stenosis of the right main bronchus in a 3-month-old child: a tracheobronchial sleeve resection under venovenous extracorporeal membrane oxygenation. European journal of cardio-thoracic surgery, 55(3), pp. 579-581. Oxford University Press 10.1093/ejcts/ezy256
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmidli, Jürg; Schmid, Ralph (2018). First Rib Resection for Thoracic Outlet Syndrome: The Robotic Approach. World journal of surgery, 42(10), pp. 3250-3255. Springer 10.1007/s00268-018-4636-4
Lutz, Jon Andri; Dorn, Patrick; Schmid, Ralph; Kocher, Gregor (2018). Upper lobe anterior segment (S3): technique of fissureless uniportal VATS segmentectomy. Journal of thoracic disease, 10(6), pp. 3797-3799. AME Publishing Company 10.21037/jtd.2018.05.88
Kocher, Gregor; Gioutsos, Konstantinos; Ahler, Markus; Funke-Chambour, Manuela; Ott, Sebastian Robert; Dorn, Patrick; Lutz, Jon Andri; Schmid, Ralph (2017). Perioperative Lung Function Monitoring for Anatomic Lung Resections. The Annals of Thoracic Surgery, 104(5), pp. 1725-1732. Elsevier 10.1016/j.athoracsur.2017.06.018
Lutz, Jon Andri; Kocher, Gregor (2017). Technical aspects of video-assisted and robotic-assisted thoracoscopic segmentectomy. Journal of thoracic disease, 9(8), pp. 2320-2322. Pioneer Bioscience Publishing 10.21037/jtd.2017.08.36
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmid, Ralph (May 2017). Thoracoscopic diaphragmatic plication made easy. British journal of surgery, 104(S4), p. 26. John Wright & Sons
Zehnder, Adrian; Kocher, Gregor; Lutz, Jon Andri; Schmid, Ralph (May 2017). Robotic first rib resection for thoracic outlet syndrome: The DaVinci-assisted minimally invasive approach. British journal of surgery, 104(S4), p. 26. John Wright & Sons
Lutz, Jon Andri; Nguyen, Thanh-Long; Schmid, Ralph; Kocher, Gregor J. (2017). Opening of the horizontal fissure as a key step for (minimally invasive) right S3-Segmentectomy. British journal of surgery, 104(Supplement_4), pp. 5-26. John Wright & Sons 10.1002/bjs.10605
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Guler, Sabina A; Machahua, Carlos; Geiser, Thomas K; Kocher, Gregor; Marti, Thomas M; Tan, Benjamin; Trappetti, Verdiana; Ryerson, Christopher J; Funke-Chambour, Manuela (2022). Dehydroepiandrosterone in fibrotic interstitial lung disease: a translational study. Respiratory research, 23(1), p. 149. BioMed Central 10.1186/s12931-022-02076-9
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Xu, Duo; Liu, Shengchen; Wu, Xi; Marti, Thomas M; Dorn, Patrick; Schmid, Ralph A; Peng, Ren-Wang; Shu, Yongqian (2022). Dissecting the Immunological Profiles in NSD3-Amplified LUSC through Integrative Multi-Scale Analyses. Cancers, 14(20) MDPI AG 10.3390/cancers14204997
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Guler, Sabina A; Machahua, Carlos; Geiser, Thomas K; Kocher, Gregor; Marti, Thomas M; Tan, Benjamin; Trappetti, Verdiana; Ryerson, Christopher J; Funke-Chambour, Manuela (2022). Dehydroepiandrosterone in fibrotic interstitial lung disease: a translational study. Respiratory research, 23(1), p. 149. BioMed Central 10.1186/s12931-022-02076-9
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
Yang, Haitang; Sun, Beibei; Fan, Liwen; Ma, Wenyan; Xu, Ke; Hall, Sean R R; Wang, Zhexin; Schmid, Ralph A; Peng, Ren-Wang; Marti, Thomas M; Gao, Wen; Xu, Jianlin; Yang, Weiwei; Yao, Feng (2022). Multi-scale integrative analyses identify THBS2+ cancer-associated fibroblasts as a key orchestrator promoting aggressiveness in early-stage lung adenocarcinoma. Theranostics, 12(7), pp. 3104-3130. Ivyspring International 10.7150/thno.69590
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Ning, Wenjuan; Marti, Thomas M; Dorn, Patrick; Peng, Ren-Wang (2022). Non-genetic adaptive resistance to KRASG12C inhibition: EMT is not the only culprit. Frontiers in oncology, 12, p. 1004669. Frontiers Research Foundation 10.3389/fonc.2022.1004669
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Yang, Haitang; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity. Cancers, 12(11) MDPI AG 10.3390/cancers12113389
Yang, Haitang; Zhao, Liang; Gao, Yanyun; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer. Cancers, 12(11) MDPI AG 10.3390/cancers12113273
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Tièche, Colin Charles; Schmid, Ralph A. (2017). Discovery and characterization of plastic subpopulations associated with distinct hallmarks of cancer in the NSCLC cell line A549. (Dissertation, Graduate School for Cellular and Biomedical Sciences)
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Marti, Thomas; Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph (2016). 23P Prolonged pemetrexed pretreatment increases efficiency of ionizing radiation combination therapy and correlates with the persistence of treatment-induced DNA damage in lung cancer cells. Journal of thoracic oncology, 11(4Suppl), S65-S65. Elsevier 10.1016/S1556-0864(16)30137-X
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph (2016). 22P Increased schedule-dependent efficiency of pemetrexed-cisplatin combination therapy eliminates resistant lung cancer stem-like cells associated with EMT. Journal of thoracic oncology, 11(4Suppl), S64-S65. Elsevier 10.1016/S1556-0864(16)30136-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. BMC cancer, 16(125), p. 125. BioMed Central 10.1186/s12885-016-2117-4
Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells. Cancer cell international, 16(66), p. 66. BioMed Central 10.1186/s12935-016-0346-x
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Meyring, Kristina; Zehnder, Adrian; Schmid, Ralph; Kocher, Gregor (2017). Thoracic surgery in patients with an implanted neurostimulator device. Interactive cardiovascular and thoracic surgery, 25(4), pp. 667-668. Oxford University Press 10.1093/icvts/ivx213
Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111
Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281
Nguyen, Thanh-Long; Schmid, Ralph; Kocher, Gregor (2017). Transmediastinal Left-Sided Video-Assisted Thoracoscopic Lung Volume Reduction Surgery after Right Upper Lobectomy for Destroyed Upper Lobe. Case reports journal, 1(1), 005. The Biomedica
Lutz, Jon Andri; Nguyen, Thanh-Long; Schmid, Ralph; Kocher, Gregor J. (2017). Opening of the horizontal fissure as a key step for (minimally invasive) right S3-Segmentectomy. British journal of surgery, 104(Supplement_4), pp. 5-26. John Wright & Sons 10.1002/bjs.10605
Ning, Wenjuan; Yang, Zhang; Kocher, Gregor J; Dorn, Patrick; Peng, Ren-Wang (2022). A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished. Cancers, 14(2) MDPI AG 10.3390/cancers14020390
Ning, Wenjuan; Marti, Thomas M; Dorn, Patrick; Peng, Ren-Wang (2022). Non-genetic adaptive resistance to KRASG12C inhibition: EMT is not the only culprit. Frontiers in oncology, 12, p. 1004669. Frontiers Research Foundation 10.3389/fonc.2022.1004669
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Früh, Martin; Betticher, Daniel C; Stupp, Roger; Xyrafas, Alexandros; Peters, Solange; Ris, Hans Beat; Mirimanoff, Rene Olivier; Ochsenbein, Adrian F.; Schmid, Ralph; Matzinger, Oscar; Stahel, Rolf A; Weder, Walter; Guckenberger, Matthias; Rothschild, Sacha I; Lardinois, Didier; Mach, Nicholas; Mark, Michael; Gautschi, Oliver; Thierstein, Sandra; Biaggi Rudolf, Christine; ... (2019). Multimodal Treatment in Operable Stage III NSCLC: A Pooled Analysis on Long-Term Results of Three SAKK trials (SAKK 16/96, 16/00, and 16/01). Journal of thoracic oncology, 14(1), pp. 115-123. Elsevier 10.1016/j.jtho.2018.09.011
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Kocher, Gregor; Gioutsos, Konstantinos; Ahler, Markus; Funke-Chambour, Manuela; Ott, Sebastian Robert; Dorn, Patrick; Lutz, Jon Andri; Schmid, Ralph (2017). Perioperative Lung Function Monitoring for Anatomic Lung Resections. The Annals of Thoracic Surgery, 104(5), pp. 1725-1732. Elsevier 10.1016/j.athoracsur.2017.06.018
Spycher, Franziska; Kocher, Gregor; Gugger, Mathias; Geiser, Thomas; Ott, Sebastian Robert (2014). Pulmonary aspergilloma: A rare differential diagnosis to lung cancer after positive FDG PET scan. Respiratory Medicine Case Reports, 12, pp. 1-3. Elsevier 10.1016/j.rmcr.2014.02.003
Gong, Xian; Du, Jianting; Peng, Ren-Wang; Chen, Chun; Yang, Zhang (2024). CRISPRing KRAS: A Winding Road with a Bright Future in Basic and Translational Cancer Research. Cancers, 16(2) MDPI AG 10.3390/cancers16020460
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Xu, Ke; Ma, Jie; Hall, Sean R R; Peng, Ren-Wang; Yang, Haitang; Yao, Feng (2023). Battles against aberrant KEAP1-NRF2 signaling in lung cancer: intertwined metabolic and immune networks. Theranostics, 13(2), pp. 704-723. Ivyspring International 10.7150/thno.80184
Xu, Duo; Liu, Shengchen; Wu, Xi; Marti, Thomas M; Dorn, Patrick; Schmid, Ralph A; Peng, Ren-Wang; Shu, Yongqian (2022). Dissecting the Immunological Profiles in NSD3-Amplified LUSC through Integrative Multi-Scale Analyses. Cancers, 14(20) MDPI AG 10.3390/cancers14204997
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
Gao, Yanyun; Kruithof-de Julio, Marianna; Peng, Ren-Wang; Dorn, Patrick (2022). Organoids as a Model for Precision Medicine in Malignant Pleural Mesothelioma: Where Are We Today? Cancers, 14(15) MDPI AG 10.3390/cancers14153758
Yang, Haitang; Yao, Feng; Peng, Ren-Wang (2022). Revisiting "BAP1ness" in Malignant Pleural Mesothelioma. Journal of thoracic oncology, 17(8), e67-e69. Elsevier 10.1016/j.jtho.2022.04.014
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Yang, Haitang; Sun, Beibei; Fan, Liwen; Ma, Wenyan; Xu, Ke; Hall, Sean R R; Wang, Zhexin; Schmid, Ralph A; Peng, Ren-Wang; Marti, Thomas M; Gao, Wen; Xu, Jianlin; Yang, Weiwei; Yao, Feng (2022). Multi-scale integrative analyses identify THBS2+ cancer-associated fibroblasts as a key orchestrator promoting aggressiveness in early-stage lung adenocarcinoma. Theranostics, 12(7), pp. 3104-3130. Ivyspring International 10.7150/thno.69590
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Ning, Wenjuan; Yang, Zhang; Kocher, Gregor J; Dorn, Patrick; Peng, Ren-Wang (2022). A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished. Cancers, 14(2) MDPI AG 10.3390/cancers14020390
Ning, Wenjuan; Marti, Thomas M; Dorn, Patrick; Peng, Ren-Wang (2022). Non-genetic adaptive resistance to KRASG12C inhibition: EMT is not the only culprit. Frontiers in oncology, 12, p. 1004669. Frontiers Research Foundation 10.3389/fonc.2022.1004669
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Yang, Haitang; Ma, Wenyan; Sun, Beibei; Fan, Liwen; Xu, Ke; Hall, Sean; Al-Hurani, Mohammad; Schmid, Ralph A.; Peng, Ren-Wang; Hida, Toyoaki; Wang, Zhexin; Yao, Feng (2021). Smoking signature is superior to programmed death-ligand 1 expression in predicting pathological response to neoadjuvant immunotherapy in lung cancer patients. Translational lung cancer research, 10(9), pp. 3807-3822. AME Publishing 10.21037/tlcr-21-734
Yang, Haitang; Sun, Beibei; Xu, Ke; He, Yunfei; Zhang, Tuo; Hall, Sean; Tan, Swee T; Schmid, Ralph A.; Peng, Ren-Wang; Hu, Guohong; Yao, Feng (2021). Pharmaco-transcriptomic correlation analysis reveals novel responsive signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer. EBioMedicine, 69(103457), p. 103457. Elsevier 10.1016/j.ebiom.2021.103457
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Zhang, Tuo; Sun, Beibei; Zhong, Chenxi; Xu, Ke; Wang, Zhexin; Hofman, Paul; Nagano, Tatsuya; Legras, Antoine; Breadner, Daniel; Ricciuti, Biagio; Divisi, Duilio; Schmid, Ralph A.; Peng, Ren-Wang; Yang, Haitang; Yao, Feng (2021). Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma. Translational lung cancer research, 10(4), pp. 1857-1872. AME Publishing 10.21037/tlcr-21-303
Yang, Haitang; Hall, Sean; Sun, Beibei; Zhao, Liang; Gao, Yanyun; Schmid, Ralph A.; Tan, Swee T; Peng, Ren-Wang; Yao, Feng (2021). NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma. Cancers, 13(7) 10.3390/cancers13071561
Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943
Yang, Haitang; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity. Cancers, 12(11) MDPI AG 10.3390/cancers12113389
Yang, Haitang; Zhao, Liang; Gao, Yanyun; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer. Cancers, 12(11) MDPI AG 10.3390/cancers12113273
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Yang, Haitang; Xu, Duo; Yang, Zhang; Yao, Feng; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2020). Systematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma. Cancers, 12(8) MDPI AG 10.3390/cancers12082310
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph; Peng, Ren-Wang (2020). Oncolytic Viral Therapy for Malignant Pleural Mesothelioma. Journal of thoracic oncology, 15(7), e111-e113. Elsevier 10.1016/j.jtho.2020.03.007
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Mohsenzadegan, Monireh; Peng, Ren-Wang; Roudi, Raheleh (2020). Dendritic cell/cytokine-induced killer cell-based immunotherapy in lung cancer: What we know and future landscape. Journal of cellular physiology, 235(1), pp. 74-86. Wiley 10.1002/jcp.28977
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph A.; Peng, Ren-Wang (2020). The Association of BAP1 Loss-of-Function With the Defect in Homologous Recombination Repair and Sensitivity to PARP-Targeted Therapy. Journal of thoracic oncology, 15(6), e88-e90. Elsevier 10.1016/j.jtho.2020.02.028
Yang, Haitang; Xu, Duo; Schmid, Ralph A.; Peng, Ren-Wang (2020). Biomarker-guided targeted and immunotherapies in malignant pleural mesothelioma. Therapeutic advances in medical oncology, 12, p. 1758835920971421. Sage 10.1177/1758835920971421
Xu, Duo; Yang, Haitang; Schmid, Ralph A.; Peng, Ren-Wang (2020). Therapeutic Landscape of Malignant Pleural Mesothelioma: Collateral Vulnerabilities and Evolutionary Dependencies in the Spotlight. Frontiers in oncology, 10, p. 579464. Frontiers Research Foundation 10.3389/fonc.2020.579464
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Yang, Haitang; Shun-Qing, Liang; Schmid, Ralph A.; Peng, Ren-Wang (2019). New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness. Frontiers in oncology, 9, p. 953. Frontiers Research Foundation 10.3389/fonc.2019.00953
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Marti, Thomas; Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph (2016). 23P Prolonged pemetrexed pretreatment increases efficiency of ionizing radiation combination therapy and correlates with the persistence of treatment-induced DNA damage in lung cancer cells. Journal of thoracic oncology, 11(4Suppl), S65-S65. Elsevier 10.1016/S1556-0864(16)30137-X
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph (2016). 22P Increased schedule-dependent efficiency of pemetrexed-cisplatin combination therapy eliminates resistant lung cancer stem-like cells associated with EMT. Journal of thoracic oncology, 11(4Suppl), S64-S65. Elsevier 10.1016/S1556-0864(16)30136-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. BMC cancer, 16(125), p. 125. BioMed Central 10.1186/s12885-016-2117-4
Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells. Cancer cell international, 16(66), p. 66. BioMed Central 10.1186/s12935-016-0346-x
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Pierog, Jaroslaw Stanislaw; Tamò, Luca Giuseppe Athos; Fakin, Richard; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Geiser, Thomas; Gazdhar, Amiq; Schmid, Ralph (2018). Bone marrow stem cells modified with human interleukin 10 attenuate acute rejection in rat lung allotransplantation. European journal of cardio-thoracic surgery, 53(1), pp. 194-200. Oxford University Press 10.1093/ejcts/ezx257
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Hoksch, Beatrix; Kocher, Gregor; Vollmar, Philippe Bernard; Praz, Fabien; Schmid, Ralph (2016). Nuss procedure for pectus excavatum in adults: long-term results in a prospective observational study. European journal of cardio-thoracic surgery, 50(5), pp. 934-939. Oxford University Press 10.1093/ejcts/ezw130
Glatzer, Markus; Leskow, Pawel; Caparrotti, Francesca; Elicin, Olgun; Furrer, Markus; Gambazzi, Franco; Dutly, André; Gelpke, Hans; Guckenberger, Matthias; Heuberger, Jürg; Inderbitzi, Rolf; Cafarotti, Stefano; Karenovics, Wolfram; Kestenholz, Peter; Kocher, Gregor; Kraxner, Peter; Krueger, Thorsten; Martucci, Francesco; Oehler, Christoph; Ozsahin, Mahmut; ... (2021). Stage III N2 non-small cell lung cancer treatment: decision-making among surgeons and radiation oncologists. Translational lung cancer research, 10(4), pp. 1960-1968. AME Publishing 10.21037/tlcr-20-1210
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
Bongoni, Anjan K; Kiermeir, David; Denoyelle, Julie Sophie Cécile; Jenni, Hansjörg; Burlak, Christopher; Seebach, Jörg D; Vögelin, Esther; Constantinescu, Mihai Adrian; Rieben, Robert (2015). Porcine extrahepatic vascular endothelial asialoglycoprotein receptor 1 mediates xenogeneic platelet phagocytosis in vitro and in human-to-pig ex vivo xenoperfusion. Transplantation, 99(4), pp. 693-701. Lippincott Williams & Wilkins 10.1097/TP.0000000000000553
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Rouiller, Benoît; Lutz, Jon A.; Kocher, Gregor J.; Magnusson, Lennart (2020). Bilateral thoracic duct ligation for persisting postoperative chylothorax. Interactive cardiovascular and thoracic surgery, 31(4), pp. 583-584. Oxford University Press 10.1093/icvts/ivaa128
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Ruppen, Janine; Wildhaber, Franziska Daniela; Strub, Christoph; Hall, Sean; Geiser, Thomas; Schmid, Ralph; Guenat, Olivier Thierry (2015). Towards personalized medicine: Chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform. Lab on a chip, 15(14), pp. 3076-3085. Royal Society of Chemistry 10.1039/C5LC00454C
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Xu, Duo; Liu, Shengchen; Wu, Xi; Marti, Thomas M; Dorn, Patrick; Schmid, Ralph A; Peng, Ren-Wang; Shu, Yongqian (2022). Dissecting the Immunological Profiles in NSD3-Amplified LUSC through Integrative Multi-Scale Analyses. Cancers, 14(20) MDPI AG 10.3390/cancers14204997
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Yang, Haitang; Sun, Beibei; Fan, Liwen; Ma, Wenyan; Xu, Ke; Hall, Sean R R; Wang, Zhexin; Schmid, Ralph A; Peng, Ren-Wang; Marti, Thomas M; Gao, Wen; Xu, Jianlin; Yang, Weiwei; Yao, Feng (2022). Multi-scale integrative analyses identify THBS2+ cancer-associated fibroblasts as a key orchestrator promoting aggressiveness in early-stage lung adenocarcinoma. Theranostics, 12(7), pp. 3104-3130. Ivyspring International 10.7150/thno.69590
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Taha, Anas; Flury, Dominik Valentin; Enodien, Bassey; Taha-Mehlitz, Stephanie; Schmid, Ralph (2022). The development of machine learning in lung surgery: A narrative review. Frontiers in Surgery, 9, p. 914903. Frontiers 10.3389/fsurg.2022.914903
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Xu, Ke; Yang, Haitang; Ma, Wenyan; Fan, Liwen; Sun, Beibei; Wang, Zhexin; Al-Hurani, Mohammad Faisal; Schmid, Ralph A.; Yao, Feng (2021). Neoadjuvant immunotherapy facilitates resection of surgically-challenging lung squamous cell cancer. Journal of thoracic disease, 13(12), pp. 6816-6826. Pioneer Bioscience Publishing 10.21037/jtd-21-1195
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Yang, Haitang; Ma, Wenyan; Sun, Beibei; Fan, Liwen; Xu, Ke; Hall, Sean; Al-Hurani, Mohammad; Schmid, Ralph A.; Peng, Ren-Wang; Hida, Toyoaki; Wang, Zhexin; Yao, Feng (2021). Smoking signature is superior to programmed death-ligand 1 expression in predicting pathological response to neoadjuvant immunotherapy in lung cancer patients. Translational lung cancer research, 10(9), pp. 3807-3822. AME Publishing 10.21037/tlcr-21-734
Zehnder, Adrian; Lutz, Jon; Dorn, Patrick; Minervini, Fabrizio; Kestenholz, Peter; Gelpke, Hans; Schmid, Ralph A.; Kocher, Gregor J. (2021). Robotic-Assisted Thoracoscopic Resection of the First Rib for Vascular Thoracic Outlet Syndrome: The New Gold Standard of Treatment? Journal of clinical medicine, 10(17) MDPI 10.3390/jcm10173952
Yang, Haitang; Sun, Beibei; Xu, Ke; He, Yunfei; Zhang, Tuo; Hall, Sean; Tan, Swee T; Schmid, Ralph A.; Peng, Ren-Wang; Hu, Guohong; Yao, Feng (2021). Pharmaco-transcriptomic correlation analysis reveals novel responsive signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer. EBioMedicine, 69(103457), p. 103457. Elsevier 10.1016/j.ebiom.2021.103457
Wang, Xiangxue; Bera, Kaustav; Barrera, Cristian; Zhou, Yu; Lu, Cheng; Vaidya, Pranjal; Fu, Pingfu; Yang, Michael; Schmid, Ralph Alexander; Berezowska, Sabina; Choi, Humberto; Velcheti, Vamsidhar; Madabhushi, Anant (2021). A prognostic and predictive computational pathology image signature for added benefit of adjuvant chemotherapy in early stage non-small-cell lung cancer. EBioMedicine, 69(103481), p. 103481. Elsevier 10.1016/j.ebiom.2021.103481
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Fan, Liwen; Yang, Haitang; Han, Ke; Zhao, Yang; Gao, Wen; Schmid, Ralph A.; Yao, Feng; Zhao, Heng (2021). Surgical Resection of Primary Tumors Provides Survival Benefits for Lung Cancer Patients With Unexpected Pleural Dissemination. Frontiers in Surgery, 8(679565), p. 679565. Frontiers 10.3389/fsurg.2021.679565
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Zhang, Tuo; Sun, Beibei; Zhong, Chenxi; Xu, Ke; Wang, Zhexin; Hofman, Paul; Nagano, Tatsuya; Legras, Antoine; Breadner, Daniel; Ricciuti, Biagio; Divisi, Duilio; Schmid, Ralph A.; Peng, Ren-Wang; Yang, Haitang; Yao, Feng (2021). Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma. Translational lung cancer research, 10(4), pp. 1857-1872. AME Publishing 10.21037/tlcr-21-303
Yang, Haitang; Al-Hurani, Mohammad; Xu, Jianlin; Fan, Liwen; Schmid, Ralph; Zhao, Heng; Yao, Feng (2021). pN1 but not pN0/N2 predicts survival benefits of prophylactic cranial irradiation in small-cell lung cancer patients after surgery. Annals of translational medicine, 9(7), p. 562. AME Publishing Company 10.21037/atm-20-6984
Yang, Haitang; Hall, Sean; Sun, Beibei; Zhao, Liang; Gao, Yanyun; Schmid, Ralph A.; Tan, Swee T; Peng, Ren-Wang; Yao, Feng (2021). NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma. Cancers, 13(7) 10.3390/cancers13071561
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Yang, Haitang; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity. Cancers, 12(11) MDPI AG 10.3390/cancers12113389
Yang, Haitang; Zhao, Liang; Gao, Yanyun; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer. Cancers, 12(11) MDPI AG 10.3390/cancers12113273
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Lu, Cheng; Bera, Kaustav; Wang, Xiangxue; Prasanna, Prateek; Xu, Jun; Janowczyk, Andrew; Beig, Niha; Yang, Michael; Fu, Pingfu; Lewis, James; Choi, Humberto; Schmid, Ralph; Berezowska, Sabina; Schalper, Kurt; Rimm, David; Velcheti, Vamsidhar; Madabhushi, Anant (2020). A prognostic model for overall survival of patients with early-stage non-small cell lung cancer: a multicentre, retrospective study. The Lancet. Digital health, 2(11), e594-e606. Elsevier 10.1016/s2589-7500(20)30225-9
Wang, Gebang; Yu, Zhanwu; Zhang, Chenlei; Zang, Hongyun; Monti, Lorenzo; Jeong, Jin Yong; Schmid, Ralph A.; Pilegaard, Hans K; Liu, Hongxu (2020). Pectus excavatum requiring temporary pacemaker implantation before Nuss procedure: a case report. Journal of thoracic disease, 12(9), pp. 4985-4990. AME Publishing Company 10.21037/jtd-20-2312
Yang, Haitang; Xu, Duo; Yang, Zhang; Yao, Feng; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2020). Systematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma. Cancers, 12(8) MDPI AG 10.3390/cancers12082310
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph; Peng, Ren-Wang (2020). Oncolytic Viral Therapy for Malignant Pleural Mesothelioma. Journal of thoracic oncology, 15(7), e111-e113. Elsevier 10.1016/j.jtho.2020.03.007
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Schmid, Ralph (2020). Key Leaders’ Opinion on Peri-Operative Risk Factor and Therapeutic Strategy in Lung Cancer Surgery. In: Guowei Che, Shuangjiang Li; Cafarotti, Stefano; Puri, Varun (eds.) Key Leaders’ Opinion on Peri-Operative Risk Factor and Therapeutic Strategy in Lung Cancer Surgery. AME Publishing Company
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph A.; Peng, Ren-Wang (2020). The Association of BAP1 Loss-of-Function With the Defect in Homologous Recombination Repair and Sensitivity to PARP-Targeted Therapy. Journal of thoracic oncology, 15(6), e88-e90. Elsevier 10.1016/j.jtho.2020.02.028
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Yang, Haitang; Xu, Duo; Schmid, Ralph A.; Peng, Ren-Wang (2020). Biomarker-guided targeted and immunotherapies in malignant pleural mesothelioma. Therapeutic advances in medical oncology, 12, p. 1758835920971421. Sage 10.1177/1758835920971421
Xu, Duo; Yang, Haitang; Schmid, Ralph A.; Peng, Ren-Wang (2020). Therapeutic Landscape of Malignant Pleural Mesothelioma: Collateral Vulnerabilities and Evolutionary Dependencies in the Spotlight. Frontiers in oncology, 10, p. 579464. Frontiers Research Foundation 10.3389/fonc.2020.579464
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Haecker, Frank-Martin; Krebs, Thomas; Kocher, Gregor; Schmid, Ralph; Sesia, Sergio Bruno (2019). Sternal elevation techniques during the minimally invasive repair of pectus excavatum. Interactive cardiovascular and thoracic surgery, 29(4), pp. 497-502. Oxford University Press 10.1093/icvts/ivz142
Schmidt Leuenberger, Joachim M; Hoksch, Beatrix; Luder, Gere; Schmid, Ralph A.; Verra, Martin L.; Dorn, Patrick (2019). Early Assessment and Management of Dysphagia After Lung Resection: A Randomized Controlled Trial. The Annals of Thoracic Surgery, 108(4), pp. 1059-1064. Elsevier 10.1016/j.athoracsur.2019.04.067
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Kocher, Gregor; Sesia, Sergio Bruno; Lopez-Hilfiker, Felipe; Schmid, Ralph (2019). Surgical smoke: still an underestimated health hazard in the operating theatre. European journal of cardio-thoracic surgery, 55(4), pp. 626-631. Oxford University Press 10.1093/ejcts/ezy356
Kocher, Gregor; Sesia, Sergio Bruno; Lopez-Hilfiker, Felipe; Schmid, Ralph (2019). Corrigendum to 'Surgical smoke: still an underestimated health hazard in the operating theatre' [Eur J Cardiothorac Surg 2019;55:626--631]. European journal of cardio-thoracic surgery, 55(4), p. 803. Oxford University Press 10.1093/ejcts/ezz017
Scholl, Heiko; Lutz, Jon Andri; Kadner, Alexander; Schmid, Ralph (2019). Dynamic stenosis of the right main bronchus in a 3-month-old child: a tracheobronchial sleeve resection under venovenous extracorporeal membrane oxygenation. European journal of cardio-thoracic surgery, 55(3), pp. 579-581. Oxford University Press 10.1093/ejcts/ezy256
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Bibby, Anna C; Dorn, Patrick; Psallidas, Ioannis; Porcel, Jose M; Janssen, Julius; Froudarakis, Marios; Subotic, Dragan; Astoul, Phillippe; Licht, Peter; Schmid, Ralph; Scherpereel, Arnaud; Rahman, Najib M; Maskell, Nick A; Cardillo, Giuseppe (2019). ERS/EACTS statement on the management of malignant pleural effusions. European journal of cardio-thoracic surgery, 55(1), pp. 116-132. Oxford University Press 10.1093/ejcts/ezy258
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Sesia, Sergio Bruno; Heitzelmann, Margarete; Schaedelin, Sabine; Magerkurth, Olaf; Kocher, Gregor; Schmid, Ralph; Haecker, Frank-Martin (2019). Standardized Haller and Asymmetry Index Combined for a More Accurate Assessment of Pectus Excavatum. The annals of thoracic surgery, 107(1), pp. 271-276. Elsevier 10.1016/j.athoracsur.2018.07.086
Früh, Martin; Betticher, Daniel C; Stupp, Roger; Xyrafas, Alexandros; Peters, Solange; Ris, Hans Beat; Mirimanoff, Rene Olivier; Ochsenbein, Adrian F.; Schmid, Ralph; Matzinger, Oscar; Stahel, Rolf A; Weder, Walter; Guckenberger, Matthias; Rothschild, Sacha I; Lardinois, Didier; Mach, Nicholas; Mark, Michael; Gautschi, Oliver; Thierstein, Sandra; Biaggi Rudolf, Christine; ... (2019). Multimodal Treatment in Operable Stage III NSCLC: A Pooled Analysis on Long-Term Results of Three SAKK trials (SAKK 16/96, 16/00, and 16/01). Journal of thoracic oncology, 14(1), pp. 115-123. Elsevier 10.1016/j.jtho.2018.09.011
Yang, Haitang; Shun-Qing, Liang; Schmid, Ralph A.; Peng, Ren-Wang (2019). New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness. Frontiers in oncology, 9, p. 953. Frontiers Research Foundation 10.3389/fonc.2019.00953
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmidli, Jürg; Schmid, Ralph (2018). First Rib Resection for Thoracic Outlet Syndrome: The Robotic Approach. World journal of surgery, 42(10), pp. 3250-3255. Springer 10.1007/s00268-018-4636-4
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Bibby, Anna C; Dorn, Patrick; Psallidas, Ioannis; Porcel, Jose M; Janssen, Julius; Froudarakis, Marios; Subotic, Dragan; Astoul, Phillippe; Licht, Peter; Schmid, Ralph; Scherpereel, Arnaud; Rahman, Najib M; Cardillo, Giuseppe; Maskell, Nick A (2018). ERS/EACTS statement on the management of malignant pleural effusions. European respiratory journal, 52(1) European Respiratory Society 10.1183/13993003.00349-2018
Dorn, Patrick; Veronesi, Giulia; Dunning, Joel; Cardillo, Giuseppe; Schmid, Ralph; Collins, Justin; Baste, Jean-Marc; Limmer, Stefan; Shahin, Ghada M M; Egberts, Jan-Hendrik; Pardolesi, Alessandro; Meacci, Elisa; Stamenkovic, Sasha; Casali, Gianluca; Rueckert, Jens C; Taurchini, Mauro; Santelmo, Nicola; Melfi, Franca; Toker, Alper (2018). Outcomes from the Delphi process of the Thoracic Robotic Curriculum Development Committee. European journal of cardio-thoracic surgery, 53(6), pp. 1173-1179. Oxford University Press 10.1093/ejcts/ezx466
Lutz, Jon Andri; Dorn, Patrick; Schmid, Ralph; Kocher, Gregor (2018). Upper lobe anterior segment (S3): technique of fissureless uniportal VATS segmentectomy. Journal of thoracic disease, 10(6), pp. 3797-3799. AME Publishing Company 10.21037/jtd.2018.05.88
Dorn, Patrick; Kuhn, Michael A; Schweizer, Barbara A; Schmid, Ralph; Kocher, Gregor (2018). Xiphoidectomy for Intractable Xiphodynia. World journal of surgery, 42(11), pp. 3646-3650. Springer-Verlag 10.1007/s00268-018-4668-9
Jafari, Morteza; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Schmid, Ralph; Geiser, Thomas; Gazdhar, Amiq; Hunger, Robert (2018). Efficacy of In Vivo Electroporation-Mediated IL-10 Gene Delivery on Survival of Skin Flaps. The Journal of Membrane Biology, 251(2), pp. 211-219. Springer 10.1007/s00232-017-9974-x
Pierog, Jaroslaw Stanislaw; Tamò, Luca Giuseppe Athos; Fakin, Richard; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Geiser, Thomas; Gazdhar, Amiq; Schmid, Ralph (2018). Bone marrow stem cells modified with human interleukin 10 attenuate acute rejection in rat lung allotransplantation. European journal of cardio-thoracic surgery, 53(1), pp. 194-200. Oxford University Press 10.1093/ejcts/ezx257
Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111
Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281
Nguyen, Thanh-Long; Schmid, Ralph; Kocher, Gregor (2017). Transmediastinal Left-Sided Video-Assisted Thoracoscopic Lung Volume Reduction Surgery after Right Upper Lobectomy for Destroyed Upper Lobe. Case reports journal, 1(1), 005. The Biomedica
Azenha Figueiredo, Luís Filipe; Schmid, Ralph; Kocher, Gregor (2017). Complex Tracheal Repair after Severe Tracheal Rupture during Percutaneous Dilatational Tracheostomy. Case reports journal, 1(1), 001. The Biomedica
Tièche, Colin Charles; Schmid, Ralph A. (2017). Discovery and characterization of plastic subpopulations associated with distinct hallmarks of cancer in the NSCLC cell line A549. (Dissertation, Graduate School for Cellular and Biomedical Sciences)
Zehnder, Adrian; Kocher, Gregor; Seitz, Michael; Schmid, Ralph (2017). IgG4-related disease of the lung: a rare differential diagnosis to lung cancer after positive positron emission tomography and biopsy. European journal of cardio-thoracic surgery, 52(5), pp. 1003-1004. Oxford University Press 10.1093/ejcts/ezx265
Kocher, Gregor; Gioutsos, Konstantinos; Ahler, Markus; Funke-Chambour, Manuela; Ott, Sebastian Robert; Dorn, Patrick; Lutz, Jon Andri; Schmid, Ralph (2017). Perioperative Lung Function Monitoring for Anatomic Lung Resections. The Annals of Thoracic Surgery, 104(5), pp. 1725-1732. Elsevier 10.1016/j.athoracsur.2017.06.018
Meyring, Kristina; Zehnder, Adrian; Schmid, Ralph; Kocher, Gregor (2017). Thoracic surgery in patients with an implanted neurostimulator device. Interactive cardiovascular and thoracic surgery, 25(4), pp. 667-668. Oxford University Press 10.1093/icvts/ivx213
Halat, Gabriel; Negrin, Lukas L; Chrysou, Konstantina; Hoksch, Beatrix; Schmid, Ralph; Kocher, Gregor (2017). Treatment of air leak in polytrauma patients with blunt chest injury. Injury - international journal of the care of the injured, 48(9), pp. 1895-1899. Elsevier 10.1016/j.injury.2017.04.061
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmid, Ralph (May 2017). Thoracoscopic diaphragmatic plication made easy. British journal of surgery, 104(S4), p. 26. John Wright & Sons
Zehnder, Adrian; Kocher, Gregor; Lutz, Jon Andri; Schmid, Ralph (May 2017). Robotic first rib resection for thoracic outlet syndrome: The DaVinci-assisted minimally invasive approach. British journal of surgery, 104(S4), p. 26. John Wright & Sons
Chrysou, Konstantina; Halat, Gabriel; Hoksch, Beatrix; Schmid, Ralph; Kocher, Gregor (2017). Lessons from a large trauma center: impact of blunt chest trauma in polytrauma patients-still a relevant problem? Scandinavian journal of trauma, resuscitation and emergency medicine, 25(1), p. 42. BioMed Central 10.1186/s13049-017-0384-y
Cortes-Dericks, Lourdes; Schmid, Ralph (2017). CD44 and its ligand hyaluronan as potential biomarkers in malignant pleural mesothelioma: evidence and perspectives. Respiratory research, 18(1), p. 58. BioMed Central 10.1186/s12931-017-0546-5
Kocher, Gregor; Zehnder, Adrian; Erdös, Gabor; Seidl, Christian Andreas; Winkler, Bernhard; Schmid, Ralph (2017). Single-cannula, single-incision thoracoscopic anatomic segmentectomy after pneumonectomy. Journal of thoracic and cardiovascular surgery, 154(2), e29-e31. Mosby 10.1016/j.jtcvs.2017.03.127
Kocher, Gregor; Zehnder, Adrian; Schmid, Ralph (2017). Completely Thoracoscopic Diaphragmatic Plication. World journal of surgery, 41(4), pp. 1019-1022. Springer 10.1007/s00268-016-3789-2
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Adamcik, Stefan; Ahler, Markus; Gioutsos, Konstantinos; Schmid, Ralph; Kocher, Gregor (2017). Repair of sternoclavicular joint dislocations with FiberWire®. Archives of orthopaedic and trauma surgery, 137(3), pp. 341-345. Springer 10.1007/s00402-017-2632-z
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Kocher, Gregor; Abu-Omar, Yasir; Bosco, Paolo; Barbero, Cristina; Waller, David; Gudbjartsson, Tomas; Sousa-Uva, Miguel; Licht, Peter B; Dunning, Joel; Schmid, Ralph; Cardillo, Giuseppe (2017). European Association for Cardio-Thoracic Surgery expert consensus statement on the prevention and management of mediastinitis. European journal of cardio-thoracic surgery, 51(1), pp. 10-29. Oxford University Press 10.1093/ejcts/ezw326
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
BG, Gorensek; Schmid, Ralph; Hoksch, Beatrix (2017). Management of Pleural Effusion by Combining Talc Poudrage and Indwelling Pleural Catheter: A Retrospective Single Center Study. Journal of clinical trials, 07(01) OMICS International 10.4172/2167-0870.1000297
Lutz, Jon Andri; Nguyen, Thanh-Long; Schmid, Ralph; Kocher, Gregor J. (2017). Opening of the horizontal fissure as a key step for (minimally invasive) right S3-Segmentectomy. British journal of surgery, 104(Supplement_4), pp. 5-26. John Wright & Sons 10.1002/bjs.10605
Kocher, Gregor; Sharafi, Siamak; Azenha Figueiredo, Luis Filipe; Schmid, Ralph (2016). Chest wall stabilization in ventilator-dependent traumatic flail chest patients: who benefits? European journal of cardio-thoracic surgery, 51(4), pp. 696-701. Oxford University Press 10.1093/ejcts/ezw365
Gioutsos, Konstantinos; Kocher, Gregor; Schmid, Ralph (2016). Robotics in pulmonology and thoracic surgery: what, why and when? Panminerva medica, 58(4), pp. 318-328. Edizioni Minerva Medica
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Hoksch, Beatrix; Kocher, Gregor; Vollmar, Philippe Bernard; Praz, Fabien; Schmid, Ralph (2016). Nuss procedure for pectus excavatum in adults: long-term results in a prospective observational study. European journal of cardio-thoracic surgery, 50(5), pp. 934-939. Oxford University Press 10.1093/ejcts/ezw130
Keil, Andreas; Hall, Sean; Körner, Meike; Herrmann, Martin; Schmid, Ralph; Frese, Steffen R. (2016). Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan. Arthritis research & therapy, 18(243), p. 243. BioMed Central 10.1186/s13075-016-1144-5
Kocher, Gregor; Gstrein, Nathalie; Jaroszewski, Dawn E; Ewais, Mennatallah M; Schmid, Ralph (2016). Nuss procedure for repair of pectus excavatum after failed Ravitch procedure in adults: indications and caveats. Journal of thoracic disease, 8(8), pp. 1981-1985. Pioneer Bioscience Publishing 10.21037/jtd.2016.06.60
Chrysou, Konstantina; Gioutsos, Konstantinos; Filips, Alexandra; Schmid, Roger; Schmid, Ralph; Kocher, Gregor (2016). Spontaneous right whole-lung torsion secondary to bronchial carcinoma: a case report. Journal of cardiothoracic surgery, 11(107), p. 107. Biomed Central 10.1186/s13019-016-0506-z
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Marti, Thomas; Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph (2016). 23P Prolonged pemetrexed pretreatment increases efficiency of ionizing radiation combination therapy and correlates with the persistence of treatment-induced DNA damage in lung cancer cells. Journal of thoracic oncology, 11(4Suppl), S65-S65. Elsevier 10.1016/S1556-0864(16)30137-X
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph (2016). 22P Increased schedule-dependent efficiency of pemetrexed-cisplatin combination therapy eliminates resistant lung cancer stem-like cells associated with EMT. Journal of thoracic oncology, 11(4Suppl), S64-S65. Elsevier 10.1016/S1556-0864(16)30136-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. BMC cancer, 16(125), p. 125. BioMed Central 10.1186/s12885-016-2117-4
Cortes, Lourdes; Froment, Laurène; Kocher, Gregor; Schmid, Ralph (2016). Human lung-derived mesenchymal stem cell-conditioned medium exerts in vitro antitumor effects in malignant pleural mesothelioma cell lines. Stem cell research & therapy, 7(1), p. 25. BioMed Central 10.1186/s13287-016-0282-7
Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells. Cancer cell international, 16(66), p. 66. BioMed Central 10.1186/s12935-016-0346-x
Kocher, Gregor; Poulson, Jannie Lysgaard; Blichfeldt-Eckhardt, Morten Rune; Elle, Bo; Schmid, Ralph; Licht, Peter B (2015). The importance of phrenic nerve preservation and its effect on long-term postoperative lung function after pneumonectomy. European journal of cardio-thoracic surgery, 49(4), pp. 1059-1062. Oxford University Press 10.1093/ejcts/ezv334
Keil, Andreas; Frese-Schaper, Manuela; Steiner, Selina; Körner, Meike; Schmid, Ralph; Frese, Steffen R. (2015). The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis. Arthritis & rheumatology, 67(7), pp. 1858-1867. Wiley-Blackwell 10.1002/art.39119
Bichsel, Colette Andrea; Hall, Sean; Schmid, Ralph; Guenat, Olivier Thierry; Geiser, Thomas (2015). Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. Tissue engineering. Part A, 21(15-16), p. 2166. Mary Ann Liebert 10.1089/ten.TEA.2014.0545
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Ruppen, Janine; Wildhaber, Franziska Daniela; Strub, Christoph; Hall, Sean; Geiser, Thomas; Schmid, Ralph; Guenat, Olivier Thierry (2015). Towards personalized medicine: Chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform. Lab on a chip, 15(14), pp. 3076-3085. Royal Society of Chemistry 10.1039/C5LC00454C
Scarci, Marco; Abah, Udo; Solli, Piergiorgio; Page, Aravinda; Waller, David; van Schil, Paul; Melfi, Franca; Schmid, Ralph; Athanassiadi, Kalliopi; Sousa Uva, Miguel; Cardillo, Giuseppe (2015). EACTS expert consensus statement for surgical management of pleural empyema. European journal of cardio-thoracic surgery, 48(5), pp. 642-653. Oxford University Press 10.1093/ejcts/ezv272
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Frese-Schaper, Manuela; Keil, Andreas; Steiner, Selina; Gugger, Mathias; Körner, Meike; Kocher, Gregor; Schiffer, Lena; Anders, Hans-Joachim; Huynh-Do, Uyen; Schmid, Ralph; Frese, Steffen R. (2014). Low dose irinotecan improves advanced lupus nephritis in mice potentially by changing DNA relaxation and anti–double-stranded DNA binding. Arthritis & rheumatology, 66(8), pp. 2259-2269. Wiley-Blackwell 10.1002/art.38665
Cortes-Dericks, Lourdes; Froment, Laurène; Boesch, Ruben; Schmid, Ralph; Karoubi, Golnaz (2014). Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity. BMC cancer, 14, p. 304. BioMed Central 10.1186/1471-2407-14-304
Frese-Schaper, Manuela; Keil, Andreas; Yagita, Hideo; Steiner, Selina; Falk, Werner; Schmid, Ralph; Frese, Steffen R. (2014). Influence of natural killer cells and perforin-mediated cytolysis on the development of chemically induced lung cancer in A/J mice. Cancer immunology, immunotherapy, 63(6), pp. 571-580. Springer 10.1007/s00262-014-1535-x
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Cortes-Dericks, Lourdes; Yazd, Ehsan Farashahi; Mowla, Seyed J.; Schmid, Ralph A.; Karoubi, Golnaz (2013). Suppression of OCT4B enhances sensitivity of lung adenocarcinoma A549 cells to cisplatin via increased apoptosis. Anticancer research, 33(12), pp. 5365-5373. International Inst. of Anticancer Research
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmidli, Jürg; Schmid, Ralph (2018). First Rib Resection for Thoracic Outlet Syndrome: The Robotic Approach. World journal of surgery, 42(10), pp. 3250-3255. Springer 10.1007/s00268-018-4636-4
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Kocher, Gregor; Zehnder, Adrian; Erdös, Gabor; Seidl, Christian Andreas; Winkler, Bernhard; Schmid, Ralph (2017). Single-cannula, single-incision thoracoscopic anatomic segmentectomy after pneumonectomy. Journal of thoracic and cardiovascular surgery, 154(2), e29-e31. Mosby 10.1016/j.jtcvs.2017.03.127
Zehnder, Adrian; Kocher, Gregor; Seitz, Michael; Schmid, Ralph (2017). IgG4-related disease of the lung: a rare differential diagnosis to lung cancer after positive positron emission tomography and biopsy. European journal of cardio-thoracic surgery, 52(5), pp. 1003-1004. Oxford University Press 10.1093/ejcts/ezx265
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Haecker, Frank-Martin; Krebs, Thomas; Kocher, Gregor; Schmid, Ralph; Sesia, Sergio Bruno (2019). Sternal elevation techniques during the minimally invasive repair of pectus excavatum. Interactive cardiovascular and thoracic surgery, 29(4), pp. 497-502. Oxford University Press 10.1093/icvts/ivz142
Kocher, Gregor; Sesia, Sergio Bruno; Lopez-Hilfiker, Felipe; Schmid, Ralph (2019). Surgical smoke: still an underestimated health hazard in the operating theatre. European journal of cardio-thoracic surgery, 55(4), pp. 626-631. Oxford University Press 10.1093/ejcts/ezy356
Kocher, Gregor; Sesia, Sergio Bruno; Lopez-Hilfiker, Felipe; Schmid, Ralph (2019). Corrigendum to 'Surgical smoke: still an underestimated health hazard in the operating theatre' [Eur J Cardiothorac Surg 2019;55:626--631]. European journal of cardio-thoracic surgery, 55(4), p. 803. Oxford University Press 10.1093/ejcts/ezz017
Sesia, Sergio Bruno; Heitzelmann, Margarete; Schaedelin, Sabine; Magerkurth, Olaf; Kocher, Gregor; Schmid, Ralph; Haecker, Frank-Martin (2019). Standardized Haller and Asymmetry Index Combined for a More Accurate Assessment of Pectus Excavatum. The annals of thoracic surgery, 107(1), pp. 271-276. Elsevier 10.1016/j.athoracsur.2018.07.086
Sesia, Sergio Bruno; Heinrich, Daniel M; Kocher, Gregor; Haecker, Frank-Martin (2018). Treatment of isolated sternal fracture with a vacuum bell in an 8-year-old boy. Interactive cardiovascular and thoracic surgery, 26(5), pp. 888-889. Oxford University Press 10.1093/icvts/ivx421
Jafari, Morteza; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Schmid, Ralph; Geiser, Thomas; Gazdhar, Amiq; Hunger, Robert (2018). Efficacy of In Vivo Electroporation-Mediated IL-10 Gene Delivery on Survival of Skin Flaps. The Journal of Membrane Biology, 251(2), pp. 211-219. Springer 10.1007/s00232-017-9974-x
Kocher, Gregor; Sharafi, Siamak; Azenha Figueiredo, Luis Filipe; Schmid, Ralph (2016). Chest wall stabilization in ventilator-dependent traumatic flail chest patients: who benefits? European journal of cardio-thoracic surgery, 51(4), pp. 696-701. Oxford University Press 10.1093/ejcts/ezw365
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Yang, Haitang; Shun-Qing, Liang; Schmid, Ralph A.; Peng, Ren-Wang (2019). New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness. Frontiers in oncology, 9, p. 953. Frontiers Research Foundation 10.3389/fonc.2019.00953
Yang, Haitang; Xu, Jianlin; Yao, Feng; Shun-Qing, Liang; Zhao, Heng (2018). Analysis of unexpected small cell lung cancer following surgery as the primary treatment. Journal of cancer research and clinical oncology, 144(12), pp. 2441-2447. Springer 10.1007/s00432-018-2766-6
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Spycher, Franziska; Kocher, Gregor; Gugger, Mathias; Geiser, Thomas; Ott, Sebastian Robert (2014). Pulmonary aspergilloma: A rare differential diagnosis to lung cancer after positive FDG PET scan. Respiratory Medicine Case Reports, 12, pp. 1-3. Elsevier 10.1016/j.rmcr.2014.02.003
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Keil, Andreas; Frese-Schaper, Manuela; Steiner, Selina; Körner, Meike; Schmid, Ralph; Frese, Steffen R. (2015). The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis. Arthritis & rheumatology, 67(7), pp. 1858-1867. Wiley-Blackwell 10.1002/art.39119
Frese-Schaper, Manuela; Keil, Andreas; Steiner, Selina; Gugger, Mathias; Körner, Meike; Kocher, Gregor; Schiffer, Lena; Anders, Hans-Joachim; Huynh-Do, Uyen; Schmid, Ralph; Frese, Steffen R. (2014). Low dose irinotecan improves advanced lupus nephritis in mice potentially by changing DNA relaxation and anti–double-stranded DNA binding. Arthritis & rheumatology, 66(8), pp. 2259-2269. Wiley-Blackwell 10.1002/art.38665
Frese-Schaper, Manuela; Keil, Andreas; Yagita, Hideo; Steiner, Selina; Falk, Werner; Schmid, Ralph; Frese, Steffen R. (2014). Influence of natural killer cells and perforin-mediated cytolysis on the development of chemically induced lung cancer in A/J mice. Cancer immunology, immunotherapy, 63(6), pp. 571-580. Springer 10.1007/s00262-014-1535-x
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Taha, Anas; Flury, Dominik Valentin; Enodien, Bassey; Taha-Mehlitz, Stephanie; Schmid, Ralph (2022). The development of machine learning in lung surgery: A narrative review. Frontiers in Surgery, 9, p. 914903. Frontiers 10.3389/fsurg.2022.914903
Pierog, Jaroslaw Stanislaw; Fytianos, Kleanthis; Tamò, Luca Giuseppe Athos; Simillion, Cedric André Marie; Taddeo, Adriano; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Heller, Manfred; Blank, Fabian; Geiser, Thomas; Schmid, Ralph; Gazdhar, Amiq (2019). Stem cell secretome attenuates acute rejection in rat lung allotransplant. Interactive cardiovascular and thoracic surgery, 28(5), pp. 812-818. Oxford University Press 10.1093/icvts/ivy306
Pierog, Jaroslaw Stanislaw; Tamò, Luca Giuseppe Athos; Fakin, Richard; Kocher, Gregor; Gugger, Mathias; Grodzki, Tomasz; Geiser, Thomas; Gazdhar, Amiq; Schmid, Ralph (2018). Bone marrow stem cells modified with human interleukin 10 attenuate acute rejection in rat lung allotransplantation. European journal of cardio-thoracic surgery, 53(1), pp. 194-200. Oxford University Press 10.1093/ejcts/ezx257
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Tièche, Colin Charles; Schmid, Ralph A. (2017). Discovery and characterization of plastic subpopulations associated with distinct hallmarks of cancer in the NSCLC cell line A549. (Dissertation, Graduate School for Cellular and Biomedical Sciences)
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Marti, Thomas; Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph (2016). 23P Prolonged pemetrexed pretreatment increases efficiency of ionizing radiation combination therapy and correlates with the persistence of treatment-induced DNA damage in lung cancer cells. Journal of thoracic oncology, 11(4Suppl), S65-S65. Elsevier 10.1016/S1556-0864(16)30137-X
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph (2016). 22P Increased schedule-dependent efficiency of pemetrexed-cisplatin combination therapy eliminates resistant lung cancer stem-like cells associated with EMT. Journal of thoracic oncology, 11(4Suppl), S64-S65. Elsevier 10.1016/S1556-0864(16)30136-8
Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. BMC cancer, 16(125), p. 125. BioMed Central 10.1186/s12885-016-2117-4
Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells. Cancer cell international, 16(66), p. 66. BioMed Central 10.1186/s12935-016-0346-x
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Guler, Sabina A; Machahua, Carlos; Geiser, Thomas K; Kocher, Gregor; Marti, Thomas M; Tan, Benjamin; Trappetti, Verdiana; Ryerson, Christopher J; Funke-Chambour, Manuela (2022). Dehydroepiandrosterone in fibrotic interstitial lung disease: a translational study. Respiratory research, 23(1), p. 149. BioMed Central 10.1186/s12931-022-02076-9
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Schmidt Leuenberger, Joachim M; Hoksch, Beatrix; Luder, Gere; Schmid, Ralph A.; Verra, Martin L.; Dorn, Patrick (2019). Early Assessment and Management of Dysphagia After Lung Resection: A Randomized Controlled Trial. The Annals of Thoracic Surgery, 108(4), pp. 1059-1064. Elsevier 10.1016/j.athoracsur.2019.04.067
Hoksch, Beatrix; Kocher, Gregor; Vollmar, Philippe Bernard; Praz, Fabien; Schmid, Ralph (2016). Nuss procedure for pectus excavatum in adults: long-term results in a prospective observational study. European journal of cardio-thoracic surgery, 50(5), pp. 934-939. Oxford University Press 10.1093/ejcts/ezw130
Bongoni, Anjan K; Kiermeir, David; Denoyelle, Julie Sophie Cécile; Jenni, Hansjörg; Burlak, Christopher; Seebach, Jörg D; Vögelin, Esther; Constantinescu, Mihai Adrian; Rieben, Robert (2015). Porcine extrahepatic vascular endothelial asialoglycoprotein receptor 1 mediates xenogeneic platelet phagocytosis in vitro and in human-to-pig ex vivo xenoperfusion. Transplantation, 99(4), pp. 693-701. Lippincott Williams & Wilkins 10.1097/TP.0000000000000553
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Yang, Haitang; Xu, Duo; Yang, Zhang; Yao, Feng; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2020). Systematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma. Cancers, 12(8) MDPI AG 10.3390/cancers12082310
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph; Peng, Ren-Wang (2020). Oncolytic Viral Therapy for Malignant Pleural Mesothelioma. Journal of thoracic oncology, 15(7), e111-e113. Elsevier 10.1016/j.jtho.2020.03.007
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph A.; Peng, Ren-Wang (2020). The Association of BAP1 Loss-of-Function With the Defect in Homologous Recombination Repair and Sensitivity to PARP-Targeted Therapy. Journal of thoracic oncology, 15(6), e88-e90. Elsevier 10.1016/j.jtho.2020.02.028
Yang, Haitang; Xu, Duo; Schmid, Ralph A.; Peng, Ren-Wang (2020). Biomarker-guided targeted and immunotherapies in malignant pleural mesothelioma. Therapeutic advances in medical oncology, 12, p. 1758835920971421. Sage 10.1177/1758835920971421
Xu, Duo; Yang, Haitang; Schmid, Ralph A.; Peng, Ren-Wang (2020). Therapeutic Landscape of Malignant Pleural Mesothelioma: Collateral Vulnerabilities and Evolutionary Dependencies in the Spotlight. Frontiers in oncology, 10, p. 579464. Frontiers Research Foundation 10.3389/fonc.2020.579464
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Yang, Haitang; Yao, Feng; Peng, Ren-Wang (2022). Revisiting "BAP1ness" in Malignant Pleural Mesothelioma. Journal of thoracic oncology, 17(8), e67-e69. Elsevier 10.1016/j.jtho.2022.04.014
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Yang, Haitang; Sun, Beibei; Xu, Ke; He, Yunfei; Zhang, Tuo; Hall, Sean; Tan, Swee T; Schmid, Ralph A.; Peng, Ren-Wang; Hu, Guohong; Yao, Feng (2021). Pharmaco-transcriptomic correlation analysis reveals novel responsive signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer. EBioMedicine, 69(103457), p. 103457. Elsevier 10.1016/j.ebiom.2021.103457
Fan, Liwen; Yang, Haitang; Han, Ke; Zhao, Yang; Gao, Wen; Schmid, Ralph A.; Yao, Feng; Zhao, Heng (2021). Surgical Resection of Primary Tumors Provides Survival Benefits for Lung Cancer Patients With Unexpected Pleural Dissemination. Frontiers in Surgery, 8(679565), p. 679565. Frontiers 10.3389/fsurg.2021.679565
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Zhang, Tuo; Sun, Beibei; Zhong, Chenxi; Xu, Ke; Wang, Zhexin; Hofman, Paul; Nagano, Tatsuya; Legras, Antoine; Breadner, Daniel; Ricciuti, Biagio; Divisi, Duilio; Schmid, Ralph A.; Peng, Ren-Wang; Yang, Haitang; Yao, Feng (2021). Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma. Translational lung cancer research, 10(4), pp. 1857-1872. AME Publishing 10.21037/tlcr-21-303
Yang, Haitang; Al-Hurani, Mohammad; Xu, Jianlin; Fan, Liwen; Schmid, Ralph; Zhao, Heng; Yao, Feng (2021). pN1 but not pN0/N2 predicts survival benefits of prophylactic cranial irradiation in small-cell lung cancer patients after surgery. Annals of translational medicine, 9(7), p. 562. AME Publishing Company 10.21037/atm-20-6984
Yang, Haitang; Hall, Sean; Sun, Beibei; Zhao, Liang; Gao, Yanyun; Schmid, Ralph A.; Tan, Swee T; Peng, Ren-Wang; Yao, Feng (2021). NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma. Cancers, 13(7) 10.3390/cancers13071561
Yang, Haitang; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity. Cancers, 12(11) MDPI AG 10.3390/cancers12113389
Yang, Haitang; Zhao, Liang; Gao, Yanyun; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer. Cancers, 12(11) MDPI AG 10.3390/cancers12113273
Yang, Haitang; Xu, Duo; Yang, Zhang; Yao, Feng; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2020). Systematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma. Cancers, 12(8) MDPI AG 10.3390/cancers12082310
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph; Peng, Ren-Wang (2020). Oncolytic Viral Therapy for Malignant Pleural Mesothelioma. Journal of thoracic oncology, 15(7), e111-e113. Elsevier 10.1016/j.jtho.2020.03.007
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Yang, Haitang; Xu, Duo; Gao, Yanyun; Schmid, Ralph A.; Peng, Ren-Wang (2020). The Association of BAP1 Loss-of-Function With the Defect in Homologous Recombination Repair and Sensitivity to PARP-Targeted Therapy. Journal of thoracic oncology, 15(6), e88-e90. Elsevier 10.1016/j.jtho.2020.02.028
Yang, Haitang; Xu, Duo; Schmid, Ralph A.; Peng, Ren-Wang (2020). Biomarker-guided targeted and immunotherapies in malignant pleural mesothelioma. Therapeutic advances in medical oncology, 12, p. 1758835920971421. Sage 10.1177/1758835920971421
Xu, Duo; Yang, Haitang; Schmid, Ralph A.; Peng, Ren-Wang (2020). Therapeutic Landscape of Malignant Pleural Mesothelioma: Collateral Vulnerabilities and Evolutionary Dependencies in the Spotlight. Frontiers in oncology, 10, p. 579464. Frontiers Research Foundation 10.3389/fonc.2020.579464
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Yang, Haitang; Shun-Qing, Liang; Schmid, Ralph A.; Peng, Ren-Wang (2019). New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness. Frontiers in oncology, 9, p. 953. Frontiers Research Foundation 10.3389/fonc.2019.00953
Yang, Haitang; Xu, Jianlin; Yao, Feng; Shun-Qing, Liang; Zhao, Heng (2018). Analysis of unexpected small cell lung cancer following surgery as the primary treatment. Journal of cancer research and clinical oncology, 144(12), pp. 2441-2447. Springer 10.1007/s00432-018-2766-6
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Ning, Wenjuan; Yang, Zhang; Kocher, Gregor J; Dorn, Patrick; Peng, Ren-Wang (2022). A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished. Cancers, 14(2) MDPI AG 10.3390/cancers14020390
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Glatzer, Markus; Leskow, Pawel; Caparrotti, Francesca; Elicin, Olgun; Furrer, Markus; Gambazzi, Franco; Dutly, André; Gelpke, Hans; Guckenberger, Matthias; Heuberger, Jürg; Inderbitzi, Rolf; Cafarotti, Stefano; Karenovics, Wolfram; Kestenholz, Peter; Kocher, Gregor; Kraxner, Peter; Krueger, Thorsten; Martucci, Francesco; Oehler, Christoph; Ozsahin, Mahmut; ... (2021). Stage III N2 non-small cell lung cancer treatment: decision-making among surgeons and radiation oncologists. Translational lung cancer research, 10(4), pp. 1960-1968. AME Publishing 10.21037/tlcr-20-1210
Zehnder, Adrian; Lutz, Jon; Dorn, Patrick; Minervini, Fabrizio; Kestenholz, Peter; Gelpke, Hans; Schmid, Ralph A.; Kocher, Gregor J. (2021). Robotic-Assisted Thoracoscopic Resection of the First Rib for Vascular Thoracic Outlet Syndrome: The New Gold Standard of Treatment? Journal of clinical medicine, 10(17) MDPI 10.3390/jcm10173952
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmidli, Jürg; Schmid, Ralph (2018). First Rib Resection for Thoracic Outlet Syndrome: The Robotic Approach. World journal of surgery, 42(10), pp. 3250-3255. Springer 10.1007/s00268-018-4636-4
Zehnder, Adrian; Kocher, Gregor; Seitz, Michael; Schmid, Ralph (2017). IgG4-related disease of the lung: a rare differential diagnosis to lung cancer after positive positron emission tomography and biopsy. European journal of cardio-thoracic surgery, 52(5), pp. 1003-1004. Oxford University Press 10.1093/ejcts/ezx265
Meyring, Kristina; Zehnder, Adrian; Schmid, Ralph; Kocher, Gregor (2017). Thoracic surgery in patients with an implanted neurostimulator device. Interactive cardiovascular and thoracic surgery, 25(4), pp. 667-668. Oxford University Press 10.1093/icvts/ivx213
Kocher, Gregor; Zehnder, Adrian; Lutz, Jon Andri; Schmid, Ralph (May 2017). Thoracoscopic diaphragmatic plication made easy. British journal of surgery, 104(S4), p. 26. John Wright & Sons
Zehnder, Adrian; Kocher, Gregor; Lutz, Jon Andri; Schmid, Ralph (May 2017). Robotic first rib resection for thoracic outlet syndrome: The DaVinci-assisted minimally invasive approach. British journal of surgery, 104(S4), p. 26. John Wright & Sons
Kocher, Gregor; Zehnder, Adrian; Erdös, Gabor; Seidl, Christian Andreas; Winkler, Bernhard; Schmid, Ralph (2017). Single-cannula, single-incision thoracoscopic anatomic segmentectomy after pneumonectomy. Journal of thoracic and cardiovascular surgery, 154(2), e29-e31. Mosby 10.1016/j.jtcvs.2017.03.127
Kocher, Gregor; Zehnder, Adrian; Schmid, Ralph (2017). Completely Thoracoscopic Diaphragmatic Plication. World journal of surgery, 41(4), pp. 1019-1022. Springer 10.1007/s00268-016-3789-2
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Zhang, Yang; Zhao, Liang; Li, Shuangjiang; Liu, Junhua (2020). Is liposomal bupivacaine superior to standard bupivacaine for pain control following minimally invasive thoracic surgery? Interactive cardiovascular and thoracic surgery, 31(2), pp. 199-203. Oxford University Press 10.1093/icvts/ivaa083
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Zhao, Liang; Li, Shuangjiang; Ju, Juan; Zhou, Haining; Wang, Hongyu; Che, Guowei (2021). Gamma-Glutamyl Transpeptidase to Platelet Ratio Is a Novel and Independent Prognostic Marker for Resectable Lung Cancer: A Propensity Score Matching Study. Annals of thoracic and cardiovascular surgery, 27(3), pp. 151-163. J-STAGE 10.5761/atcs.oa.20-00247
Yang, Haitang; Hall, Sean; Sun, Beibei; Zhao, Liang; Gao, Yanyun; Schmid, Ralph A.; Tan, Swee T; Peng, Ren-Wang; Yao, Feng (2021). NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma. Cancers, 13(7) 10.3390/cancers13071561
Yang, Haitang; Zhao, Liang; Gao, Yanyun; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer. Cancers, 12(11) MDPI AG 10.3390/cancers12113273
Zhang, Yang; Zhao, Liang; Li, Shuangjiang; Liu, Junhua (2020). Is liposomal bupivacaine superior to standard bupivacaine for pain control following minimally invasive thoracic surgery? Interactive cardiovascular and thoracic surgery, 31(2), pp. 199-203. Oxford University Press 10.1093/icvts/ivaa083
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Blom, Rebecca Agaatha Maria; Amacker, Mario; Moser, Christian; van Dijk, R Maarten; Bonetti, Raffaela; Seydoux, Emilie; Hall, Sean; von Garnier, Christophe; Blank, Fabian (2017). Virosome-bound antigen enhances DC-dependent specific CD4(+) T cell stimulation, inducing a Th1 and Treg profile in vitro. Nanomedicine : nanotechnology, biology, and medicine, 13(5), pp. 1725-1737. Elsevier 10.1016/j.nano.2017.02.004
Blom, Rebecca Agaatha Maria; Erni, Silvia T; Krempaská, Kristína; Schaerer, Olivier; van Dijk, R Maarten; Amacker, Mario; Moser, Christian; Hall, Sean; Von Garnier, Christophe; Blank, Fabian (2016). A Triple Co-Culture Model of the Human Respiratory Tract to Study Immune-Modulatory Effects of Liposomes and Virosomes. PLoS ONE, 11(9), e0163539. Public Library of Science 10.1371/journal.pone.0163539
