Peinelt, Christine

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2018

Ozhathil, Lijo Cherian; Delalande, Clémence Marie Sandrine; Bianchi, Beatrice; Nemeth, Gabor; Kappel, Sven; Thomet, Urs; Ross, Daniela; Simonin, Céline; Rubin, Matthias; Gertsch, Jürg; Lochner, Martin; Peinelt, Christine; Reymond, Jean-Louis; Abriel, Hugues (2018). Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. British journal of pharmacology, 175(12), pp. 2504-2519. Wiley-Blackwell 10.1111/bph.14220

2017

Kappel, Sven; dos Santos Marques, Ines Joao; Zoni, Eugenio; Stoklosa, Paulina Agnieszka; Peinelt, Christine; Mercader Huber, Nadia; Kruithof-de Julio, Marianna; Borgström, Anna (2017). Store-Operated Ca2+ Entry as a Prostate Cancer Biomarker — a Riddle with Perspectives. Current Molecular Biology Reports, 3(4), pp. 208-217. Springer 10.1007/s40610-017-0072-8

2016

Dörr, Kathrin; Kilch, Tatiana; Kappel, Sven; Alansary, Dalia; Schwär, Gertrud; Niemeyer, Barbara A; Peinelt, Christine (2016). Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry. Science signaling, 9(418), ra25. American Association for the Advancement of Science 10.1126/scisignal.aaa9913

Kilch, Tatiana; Kappel, Sven; Peinelt, Christine (2016). Regulation of Ca(2+) signaling in prostate cancer cells. Channels, 10(3), pp. 170-171. Taylor & Francis 10.1080/19336950.2015.1137176

2015

Holzmann, Christian; Kappel, Sven; Kilch, Tatiana; Jochum, Marcus Martin; Urban, Sabine Katharina; Jung, Volker; Stöckle, Michael; Rother, Karen; Greiner, Markus; Peinelt, Christine (2015). Transient receptor potential melastatin 4 channel contributes to migration of androgen-insensitive prostate cancer cells. OncoTarget, 6(39), pp. 41783-41793. Impact Journals LLC 10.18632/oncotarget.6157

Holzmann, Christian; Kilch, Tatiana; Kappel, Sven; Dörr, Kathrin; Jung, Volker; Stöckle, Michael; Bogeski, Ivan; Peinelt, Christine (2015). Differential Redox Regulation of Ca²⁺ Signaling and Viability in Normal and Malignant Prostate Cells. Biophysical journal, 109(7), pp. 1410-1419. Biophysical Society 10.1016/j.bpj.2015.08.006

2014

Beck, Andreas; Fleig, Andrea; Penner, Reinhold; Peinelt, Christine (2014). Regulation of endogenous and heterologous Ca²⁺ release-activated Ca²⁺ currents by pH. Cell calcium, 56(3), pp. 235-243. Elsevier 10.1016/j.ceca.2014.07.011

Alansary, Dalia; Kilch, Tatiana; Holzmann, Christian; Peinelt, Christine; Hoth, Markus; Lis, Annette (2014). Patch-clamp measurement of ICRAC and ORAI channel activity. Cold Spring Harbor protocols, 2014(6), pp. 602-607. Cold Spring Harbor Laboratory 10.1101/pdb.top066795

Alansary, Dalia; Kilch, Tatiana; Holzmann, Christian; Peinelt, Christine; Hoth, Markus; Lis, Annette (2014). The minimal requirements to use calcium imaging to analyze ICRAC. Cold Spring Harbor protocols, 2014(6), pp. 638-642. Cold Spring Harbor Laboratory 10.1101/pdb.prot073262

Alansary, Dalia; Kilch, Tatiana; Holzmann, Christian; Peinelt, Christine; Hoth, Markus; Lis, Annette (2014). Measuring endogenous ICRAC and ORAI currents with the patch-clamp technique. Cold Spring Harbor protocols, 2014(6), pp. 630-637. Cold Spring Harbor Laboratory 10.1101/pdb.prot073254

2013

Holzmann, Christian; Kilch, Tatiana; Kappel, Sven; Armbrüster, Andrea; Jung, Volker; Stöckle, Michael; Bogeski, Ivan; Schwarz, Eva C; Peinelt, Christine (2013). ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer. OncoTarget, 4(11), pp. 2096-2107. Impact Journals LLC 10.18632/oncotarget.1483

Carreras-Sureda, Amado; Cantero-Recasens, Gerard; Rubio-Moscardo, Fanny; Kiefer, Kerstin; Peinelt, Christine; Niemeyer, Barbara A; Valverde, Miguel A; Vicente, Rubén (2013). ORMDL3 modulates store-operated calcium entry and lymphocyte activation. Human molecular genetics, 22(3), pp. 519-530. Oxford University Press 10.1093/hmg/dds450

Kilch, Tatiana; Alansary, Dalia; Peglow, Martin; Dörr, Kathrin; Rychkov, Grigori; Rieger, Heiko; Peinelt, Christine; Niemeyer, Barbara A (2013). Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1. Journal of biological chemistry, 288(3), pp. 1653-1664. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.417246

2012

Stanisz, Hedwig; Stark, Alexandra; Kilch, Tatiana; Schwarz, Eva C; Müller, Cornelia S L; Peinelt, Christine; Hoth, Markus; Niemeyer, Barbara A; Vogt, Thomas; Bogeski, Ivan (2012). ORAI1 Ca(2+) channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytes. Journal of Investigative Dermatology, 132(5), pp. 1443-1451. Nature Publishing 10.1038/jid.2011.478

2010

Lis, Annette; Zierler, Susanna; Peinelt, Christine; Fleig, Andrea; Penner, Reinhold (2010). A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating. Journal of general physiology, 136(6), pp. 673-686. Rockefeller University Press 10.1085/jgp.201010484

Bogeski, Ivan; Al-Ansary, Dalia; Qu, Bin; Niemeyer, Barbara A; Hoth, Markus; Peinelt, Christine (2010). Pharmacology of ORAI channels as a tool to understand their physiological functions. Expert review of clinical pharmacology, 3(3), pp. 291-303. Taylor & Francis 10.1586/ecp.10.23

Bogeski, Ivan; Kummerow, Carsten; Al-Ansary, Dalia; Schwarz, Eva C; Koehler, Richard; Kozai, Daisuke; Takahashi, Nobuaki; Peinelt, Christine; Griesemer, Desiree; Bozem, Monika; Mori, Yasuo; Hoth, Markus; Niemeyer, Barbara A (2010). Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. Science signaling, 3(115), ra24. American Association for the Advancement of Science 10.1126/scisignal.2000672

2009

Peinelt, Christine; Beck, Andreas; Monteilh-Zoller, Mahealani K; Penner, Reinhold; Fleig, Andrea (2009). IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC). Cell calcium, 45(4), pp. 326-330. Elsevier 10.1016/j.ceca.2008.12.001

2008

Peinelt, Christine; Lis, Annette; Beck, Andreas; Fleig, Andrea; Penner, Reinhold (2008). 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. Journal of physiology, 586(13), pp. 3061-3073. Wiley-Blackwell 10.1113/jphysiol.2008.151365

Parvez, Suhel; Beck, Andreas; Peinelt, Christine; Soboloff, Jonathan; Lis, Annette; Monteilh-Zoller, Mahealani; Gill, Donald L; Fleig, Andrea; Penner, Reinhold (2008). STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation. FASEB journal, 22(3), pp. 752-761. Federation of American Societies for Experimental Biology 10.1096/fj.07-9449com

2007

Lis, Annette; Peinelt, Christine; Beck, Andreas; Parvez, Suhel; Monteilh-Zoller, Mahealani; Fleig, Andrea; Penner, Reinhold (2007). CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties. Current Biology, 17(9), pp. 794-800. Cell Press 10.1016/j.cub.2007.03.065

2006

Vig, Monika; Beck, Andreas; Billingsley, James M; Lis, Annette; Parvez, Suhel; Peinelt, Christine; Koomoa, Dana L; Soboloff, Jonathan; Gill, Donald L; Fleig, Andrea; Kinet, Jean-Pierre; Penner, Reinhold (2006). CRACM1 multimers form the ion-selective pore of the CRAC channel. Current Biology, 16(20), pp. 2073-2079. Cell Press 10.1016/j.cub.2006.08.085

Peinelt, Christine; Vig, Monika; Koomoa, Dana L; Beck, Andreas; Nadler, Monica J S; Koblan-Huberson, Murielle; Lis, Annette; Fleig, Andrea; Penner, Reinhold; Kinet, Jean-Pierre (2006). Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nature cell biology, 8(7), pp. 771-773. Nature Publishing Group 10.1038/ncb1435

Vig, M; Peinelt, Christine; Beck, A; Koomoa, D L; Rabah, D; Koblan-Huberson, M; Kraft, S; Turner, H; Fleig, A; Penner, R; Kinet, J-P (2006). CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry. Science, 312(5777), pp. 1220-1223. American Association for the Advancement of Science 10.1126/science.1127883

2005

Peinelt, Christine; Apell, Hans-Jürgen (2005). Kinetics of Ca2+ binding to the SR Ca-ATPase in the E1 state. Biophysical journal, 89(4), pp. 2427-2433. Biophysical Society 10.1529/biophysj.105.068411

2004

Peinelt, Christine; Apell, Hans-Jürgen (2004). Time-resolved charge movements in the sarcoplasmatic reticulum Ca-ATPase. Biophysical journal, 86(2), pp. 815-824. Biophysical Society 10.1016/S0006-3495(04)74157-0

2003

Peinelt, Christine; Apell, Hans-Jürgen (2003). Time-resolved partial reactions of the SR Ca-ATPase investigated with a fluorescent styryl dye. Annals of the New York Academy of Sciences, 986, pp. 325-326. Blackwell

2002

Peinelt, Christine; Apell, Hans-Jürgen (2002). Kinetics of the Ca(2+), H(+), and Mg(2+) interaction with the ion-binding sites of the SR Ca-ATPase. Biophysical journal, 82(1 Pt 1), pp. 170-181. Biophysical Society 10.1016/S0006-3495(02)75384-8

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