Rottenberg, Sven

Up a level
Export as [feed] RSS
Group by: Date | Item Type | Refereed | No Grouping
Jump to: 2018 | 2017 | 2016 | 2015 | 2014 | 2003

2018

Gogola, Ewa; Duarte, Alexandra A; de Ruiter, Julian R; Wiegant, Wouter W; Schmid, Jonas A; de Bruijn, Roebi; James, Dominic I; Guerrero Llobet, Sergi; Vis, Daniel J; Annunziato, Stefano; van den Broek, Bram; Barazas, Marco; Kersbergen, Ariena; van de Ven, Marieke; Tarsounas, Madalena; Ogilvie, Donald J; van Vugt, Marcel; Wessels, Lodewyk F A; Bartkova, Jirina; Gromova, Irina; ... (2018). Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality. Cancer cell, 33(6), 1078-1093.e12. Cell Press 10.1016/j.ccell.2018.05.008

Gerhards, Nora Merete; Blomen, Vincent A; Mutlu, Merve; Nieuwenhuis, Joppe; Howald, Denise; Guyader, Charlotte; Jonkers, Jos; Brummelkamp, Thijn R; Rottenberg, Sven (2018). Haploid genetic screens identify genetic vulnerabilities to microtubule-targeting agents. Molecular oncology, 12(6), pp. 953-971. Elsevier 10.1002/1878-0261.12307

Duarte, Alexandra A; Gogola, Ewa; Sachs, Norman; Barazas, Marco; Annunziato, Stefano; R de Ruiter, Julian; Velds, Arno; Blatter, Sohvi Tuulikki; Houthuijzen, Julia M; van de Ven, Marieke; Clevers, Hans; Borst, Piet; Jonkers, Jos; Rottenberg, Sven (2018). BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance. Nature methods, 15(2), pp. 134-140. Nature Publishing Group 10.1038/nmeth.4535

Sachs, Norman; de Ligt, Joep; Kopper, Oded; Gogola, Ewa; Bounova, Gergana; Weeber, Fleur; Balgobind, Anjali Vanita; Wind, Karin; Gracanin, Ana; Begthel, Harry; Korving, Jeroen; van Boxtel, Ruben; Duarte, Alexandra Alves; Lelieveld, Daphne; van Hoeck, Arne; Ernst, Robert Frans; Blokzijl, Francis; Nijman, Isaac Johannes; Hoogstraat, Marlous; van de Ven, Marieke; ... (2018). A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity. Cell, 172(1-2), pp. 373-386. Cell Press 10.1016/j.cell.2017.11.010

Gerhards, Nora Merete; Rottenberg, Sven (2018). New tools for old drugs: Functional genetic screens to optimize current chemotherapy. Drug Resistance Updates, 36, pp. 30-46. Elsevier 10.1016/j.drup.2018.01.001

2017

Pajic, Marina; Blatter, Sohvi Tuulikki; Guyader, Charlotte; Gonggrijp, Maaike; Kersbergen, Ariena; Küçükosmanoğlu, Aslι; Sol, Wendy; Drost, Rinske; Jonkers, Jos; Borst, Piet; Rottenberg, Sven (2017). Selected Alkylating Agents Can Overcome Drug Tolerance of G-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice. Clinical cancer research, 23(22), pp. 7020-7033. American Association for Cancer Research 10.1158/1078-0432.CCR-17-1279

Rondinelli, Beatrice; Gogola, Ewa; Yücel, Hatice; Duarte, Alexandra A; van de Ven, Marieke; van der Sluijs, Roxanne; Konstantinopoulos, Panagiotis A; Jonkers, Jos; Ceccaldi, Raphaël; Rottenberg, Sven; D'Andrea, Alan D (2017). EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation. Nature cell biology, 19(11), pp. 1371-1378. Nature Publishing Group 10.1038/ncb3626

Borst, Gerben R; Kumareswaran, Ramya; Yücel, Hatice; Telli, Seyda; Do, Trevor; McKee, Trevor; Zafarana, Gaetano; Jonkers, Jos; Verheij, Marcel; O'Connor, Mark J; Rottenberg, Sven; Bristow, Robert G (2017). Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model. OncoTarget, 8(50), pp. 87638-87646. Impact Journals LLC 10.18632/oncotarget.20936

Schoonen, Pepijn M; Talens, Francien; Stok, Colin; Gogola, Ewa; Heijink, Anne Margriet; Bouwman, Peter; Foijer, Floris; Tarsounas, Madalena; Blatter, Sohvi Tuulikki; Jonkers, Jos; Rottenberg, Sven; van Vugt, Marcel A T M (2017). Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells. Nature communications, 8(15981), p. 15981. Nature Publishing Group 10.1038/ncomms15981

2016

Annunziato, Stefano; Barazas, Marco; Rottenberg, Sven; Jonkers, Jos (2016). Genetic Dissection of Cancer Development, Therapy Response, and Resistance in Mouse Models of Breast Cancer. Cold Spring Harbor Symposia on Quantitative Biology, 81, pp. 141-150. Biological Laboratory 10.1101/sqb.2016.81.030924

Oplustil O'Connor, Lenka; Rulten, Stuart L; Cranston, Aaron N; Odedra, Rajesh; Brown, Henry; Jaspers, Janneke E; Jones, Louise; Knights, Charlotte; Evers, Bastiaan; Ting, Attilla; Bradbury, Robert H; Pajic, Marina; Rottenberg, Sven; Jonkers, Jos; Rudge, David; Martin, Niall M B; Caldecott, Keith W; Lau, Alan; O'Connor, Mark J (2016). The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models. Cancer research, 76(20), pp. 6084-6094. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-3240

Warmoes, Marc; Lam, Siu W; van der Groep, Petra; Jaspers, Janneke E; Smolders, Yvonne H C M; de Boer, Leon; Pham, Thang V; Piersma, Sander R; Rottenberg, Sven; Boven, Epie; Jonkers, Jos; van Diest, Paul J; Jimenez, Connie R (2016). Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer. OncoTarget, 7(39), pp. 63537-63548. Impact Journals LLC 10.18632/oncotarget.11535

Drost, Rinske; Dhillon, Kiranjit K; van der Gulden, Hanneke; van der Heijden, Ingrid; Brandsma, Inger; Cruz, Cristina; Chondronasiou, Dafni; Castroviejo-Bermejo, Marta; Boon, Ute; Schut, Eva; van der Burg, Eline; Wientjens, Ellen; Pieterse, Mark; Klijn, Christiaan; Klarenbeek, Sjoerd; Loayza-Puch, Fabricio; Elkon, Ran; van Deemter, Liesbeth; Rottenberg, Sven; van de Ven, Marieke; ... (2016). BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1. Journal of clinical investigation, 126(8), pp. 2903-2918. American Society for Clinical Investigation 10.1172/JCI70196

Ray Chaudhuri, Arnab; Callen, Elsa; Ding, Xia; Gogola, Ewa; Duarte, Alexandra A; Lee, Ji-Eun; Wong, Nancy; Lafarga, Vanessa; Calvo, Jennifer A; Panzarino, Nicholas J; John, Sam; Day, Amanda; Crespo, Anna Vidal; Shen, Binghui; Starnes, Linda M; de Ruiter, Julian R; Daniel, Jeremy A; Konstantinopoulos, Panagiotis A; Cortez, David; Cantor, Sharon B; ... (2016). Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature, 535(7612), pp. 382-387. Macmillan Journals Ltd. 10.1038/nature18325

Tkáč, Ján; Xu, Guotai; Adhikary, Hemanta; Young, Jordan T F; Gallo, David; Escribano-Díaz, Cristina; Krietsch, Jana; Orthwein, Alexandre; Munro, Meagan; Sol, Wendy; Al-Hakim, Abdallah; Lin, Zhen-Yuan; Jonkers, Jos; Borst, Piet; Brown, Grant W; Gingras, Anne-Claude; Rottenberg, Sven; Masson, Jean-Yves; Durocher, Daniel (2016). HELB Is a Feedback Inhibitor of DNA End Resection. Molecular cell, 61(3), pp. 405-418. Cell Press 10.1016/j.molcel.2015.12.013

Hendrikx, Jeroen J M A; Lagas, Jurjen S; Song, Ji-Ying; Rosing, Hilde; Schellens, Jan H M; Beijnen, Jos H; Rottenberg, Sven; Schinkel, Alfred H (2016). Ritonavir inhibits intratumoral docetaxel metabolism and enhances docetaxel antitumor activity in an immunocompetent mouse breast cancer model. International journal of cancer, 138(3), pp. 758-769. Wiley-Blackwell 10.1002/ijc.29812

2015

Planells-Cases, Rosa; Lutter, Darius; Guyader, Charlotte; Gerhards, Nora Merete; Ullrich, Florian; Elger, Deborah A; Kucukosmanoglu, Asli; Xu, Guotai; Voss, Felizia K; Reincke, S Momsen; Stauber, Tobias; Blomen, Vincent A; Vis, Daniel J; Wessels, Lodewyk F; Brummelkamp, Thijn R; Borst, Piet; Rottenberg, Sven; Jentsch, Thomas J (2015). Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs. The EMBO Journal, 34(24), pp. 2993-3008. EMBO Press 10.15252/embj.201592409

Yu, Huixin; Hendrikx, Jeroen J M A; Rottenberg, Sven; Schellens, Jan H M; Beijnen, Jos H; Huitema, Alwin D R (2015). Development of a Tumour Growth Inhibition Model to Elucidate the Effects of Ritonavir on Intratumoural Metabolism and Anti-tumour Effect of Docetaxel in a Mouse Model for Hereditary Breast Cancer. AAPS journal, 18(2), pp. 362-371. American Association of Pharmaceutical Scientists 10.1208/s12248-015-9838-1

Henneman, Linda; van Miltenburg, Martine H; Michalak, Ewa M; Braumuller, Tanya M; Jaspers, Janneke E; Drenth, Anne Paulien; de Korte-Grimmerink, Renske; Gogola, Ewa; Szuhai, Karoly; Schlicker, Andreas; Bin Ali, Rahmen; Pritchard, Colin; Huijbers, Ivo J; Berns, Anton; Rottenberg, Sven; Jonkers, Jos (2015). Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 112(27), pp. 8409-8414. National Academy of Sciences NAS 10.1073/pnas.1500223112

Nachabé, Rami; Hendriks, Benno H W; Schierling, Ross; Hales, Jasmine; Racadio, Judy M; Rottenberg, Sven; Ruers, Theo J M; Babic, Drazenko; Racadio, John M (2015). Real-Time In Vivo Characterization of Primary Liver Tumors With Diffuse Optical Spectroscopy During Percutaneous Needle Interventions: Feasibility Study in Woodchucks. Investigative radiology, 50(7), pp. 443-448. Lippincott Williams & Wilkins 10.1097/RLI.0000000000000149

Xu, Guotai; Chapman, J Ross; Brandsma, Inger; Yuan, Jingsong; Mistrik, Martin; Bouwman, Peter; Bartkova, Jirina; Gogola, Ewa; Warmerdam, Daniël; Barazas, Marco; Jaspers, Janneke E; Watanabe, Kenji; Pieterse, Mark; Kersbergen, Ariena; Sol, Wendy; Celie, Patrick H N; Schouten, Philip C; van den Broek, Bram; Salman, Ahmed; Nieuwland, Marja; ... (2015). REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature, 521(7553), pp. 541-544. Macmillan Journals Ltd. 10.1038/nature14328

Jaspers, Janneke E; Sol, Wendy; Kersbergen, Ariena; Schlicker, Andreas; Guyader, Charlotte; Xu, Guotai; Wessels, Lodewyk; Borst, Piet; Jonkers, Jos; Rottenberg, Sven (2015). BRCA2-Deficient Sarcomatoid Mammary Tumors Exhibit Multidrug Resistance. Cancer research, 75(4), pp. 732-741. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-14-0839

Kuilman, Thomas; Velds, Arno; Kemper, Kristel; Ranzani, Marco; Bombardelli, Lorenzo; Hoogstraat, Marlous; Nevedomskaya, Ekaterina; Xu, Guotai; de Ruiter, Julian; Lolkema, Martijn P; Ylstra, Bauke; Jonkers, Jos; Rottenberg, Sven; Wessels, Lodewyk F; Adams, David J; Peeper, Daniel S; Krijgsman, Oscar (2015). CopywriteR: DNA copy number detection from off-target sequence data. Genome biology, 16(49), p. 49. BioMed Central Ltd. 10.1186/s13059-015-0617-1

Blatter, Sohvi; Rottenberg, Sven (2015). Minimal residual disease in cancer therapy - Small things make all the difference. Drug Resistance Updates, 21-22, pp. 1-10. Churchill Livingstone 10.1016/j.drup.2015.08.003

van Asten, Jack J A; Vettukattil, Riyas; Buckle, Tessa; Rottenberg, Sven; van Leeuwen, Fijs; Bathen, Tone F; Heerschap, Arend (2015). Increased levels of choline metabolites are an early marker of docetaxel treatment response in BRCA1-mutated mouse mammary tumors: an assessment by ex vivo proton magnetic resonance spectroscopy. Journal of translational medicine, 13(114), p. 114. BioMed Central 10.1186/s12967-015-0458-4

Xu, Guotai; Jonkers, Jos; Rottenberg, Sven (2015). PARP Inhibitor Resistance - What Is Beyond BRCA1 or BRCA2 Restoration? In: Curtin, Nicola J.; Sharma, Ricky A. (eds.) PARP Inhibitor Resistance—What Is Beyond BRCA1 or BRCA2 Restoration? Cancer Drug Discovery and Development: Vol. 83 (pp. 453-471). Cham: Springer International Publishing 10.1007/978-3-319-14151-0_19

2014

Spliethoff, Jarich W; Evers, Daniel J; Jaspers, Janneke E; Hendriks, Benno H W; Rottenberg, Sven; Ruers, Theo J M (2014). Monitoring of tumor response to Cisplatin using optical spectroscopy. Translational oncology, 7(2), pp. 230-239. Elsevier 10.1016/j.tranon.2014.02.009

2003

Dobbelaere, Dirk; Rottenberg, Sven (2003). Theileria-induced leukocyte transformation. Current opinion in microbiology, 6(4), pp. 377-382. London: Current Biology Ltd. 10.1016/S1369-5274(03)00085-7

Provide Feedback