Thiel, Volker Earl

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Journal Article

Gultom, Mitra; Kratzel, Annika; Portmann, Jasmine; Stalder, Hanspeter; Chanfon Bätzner, Astrid; Gantenbein, Hans; Gurtner, Corinne; Ebert, Nadine; Gad, Hans Henrik; Hartmann, Rune; Posthaus, Horst; Zanolari, Patrik; Pfaender, Stephanie; Thiel, Volker Earl; Dijkman, Ronald (2022). Establishment of well-differentiated camelid airway cultures to study Middle East respiratory syndrome coronavirus. Scientific reports, 12(1), p. 10340. Springer Nature 10.1038/s41598-022-13777-y

Dijkman, Ronald; Verma, Abhishek Kumar; Selvaraj, Muneeswaran; Ghimire, Roshan; Gad, Hans Henrik; Hartmann, Rune; More, Sunil; Perlman, Stanley; Thiel, Volker Earl; Channappanavar, Rudragouda (2022). Effective Interferon Lambda Treatment Regimen To Control Lethal MERS-CoV Infection in Mice. Journal of virology, 96(11), e0036422. American Society for Microbiology 10.1128/jvi.00364-22

V'kovski, Philip; Gerber, Markus; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga Lagache, Sophie; Simillion, Cedric; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (2019). Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling. eLife, 8 eLife Sciences Publications 10.7554/eLife.42037

Alves, Marco; Vielle, Nathalie Jane; Thiel, Volker Earl; Pfänder, Stephanie (2018). Research Models and Tools for the Identification of Antivirals and Therapeutics against Zika Virus Infection. Viruses, 10(11) MDPI 10.3390/v10110593

Muth, Doreen; Corman, Victor Max; Roth, Hanna; Binger, Tabea; Dijkman, Ronald; Gottula, Lina Theresa; Gloza-Rausch, Florian; Balboni, Andrea; Battilani, Mara; Rihtarič, Danijela; Toplak, Ivan; Ameneiros, Ramón Seage; Pfeifer, Alexander; Thiel, Volker Earl; Drexler, Jan Felix; Müller, Marcel Alexander; Drosten, Christian (2018). Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission. Scientific Reports, 8(1), p. 15177. Nature Publishing Group 10.1038/s41598-018-33487-8

Thiel, Volker Earl (2018). Synthetic viruses-Anything new? PLoS pathogens, 14(10), e1007019. Public Library of Science 10.1371/journal.ppat.1007019

Ibrahim, Bashar; McMahon, Dino P; Hufsky, Franziska; Beer, Martin; Deng, Li; Mercier, Philippe Le; Palmarini, Massimo; Thiel, Volker Earl; Marz, Manja (2018). A new era of virus bioinformatics. Virus research, 251, pp. 86-90. Elsevier 10.1016/j.virusres.2018.05.009

Milewska, Aleksandra; Kindler, Eveline Patricia; V'Kovski, Philip; Zeglen, S; Ochman, M; Thiel, Volker Earl; Rajfur, Z; Pyrc, K (2018). APOBEC3-mediated restriction of RNA virus replication. Scientific Reports, 8(1), p. 5960. Nature Publishing Group 10.1038/s41598-018-24448-2

Rappe, Julie Christiane Françoise; de Wilde, Adriaan; Di, Han; Müller, Christin; Stalder, Hanspeter; V'Kovski, Philip; Snijder, Eric; Brinton, Margo A; Ziebuhr, John; Ruggli, Nicolas; Thiel, Volker Earl (2018). Antiviral activity of K22 against members of the order Nidovirales. Virus research, 246, pp. 28-34. Elsevier 10.1016/j.virusres.2018.01.002

Hufsky, Franziska; Ibrahim, Bashar; Beer, Martin; Deng, Li; Mercier, Philippe Le; McMahon, Dino P; Palmarini, Massimo; Thiel, Volker Earl; Marz, Manja (2018). Virologists-Heroes need weapons. PLoS pathogens, 14(2), e1006771. Public Library of Science 10.1371/journal.ppat.1006771

Behrendt, Patrick; Perin, Paula; Menzel, Nicolas; Banda, Dominic; Pfänder, Stephanie; Alves, Marco; Thiel, Volker Earl; Meulemann, Phillip; Colpitts, Che C; Schang, Luis M; Vondran, Florian W R; Anggakusuma, A; Manns, Michael P; Steinmann, Eike; Pietschmann, Thomas (2017). Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral research, 147, pp. 19-28. Elsevier 10.1016/j.antiviral.2017.09.006

Pfänder, Stephanie; Walter, Stephanie; Grabski, Elena; Todt, Daniel; Bruening, Janina; Romero-Brey, Inés; Gather, Theresa; Brown, Richard J P; Hahn, Kerstin; Puff, Christina; Pfankuche, Vanessa M; Hansmann, Florian; Postel, Alexander; Becher, Paul; Thiel, Volker Earl; Kalinke, Ulrich; Wagner, Bettina; Bartenschlager, Ralf; Baumgärtner, Wolfgang; Feige, Karsten; ... (2017). Immune protection against reinfection with nonprimate hepacivirus. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(12), E2430-E2439. National Academy of Sciences NAS 10.1073/pnas.1619380114

Siddharta, Anindya; Pfänder, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P; Brill, Florian H; Steinmann, Joerg; Steinmann, Jochen; Becker, Stephan; Alves, Marco; Pietschmann, Thomas; Eickmann, Markus; Thiel, Volker Earl; Steinmann, Eike (2017). Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. Journal of infectious diseases, 215(6), pp. 902-906. Oxford University Press 10.1093/infdis/jix046

Kindler, Eveline Patricia; Gil-Cruz, Cristina; Spanier, Julia; Li, Yize; Wilhelm, Jochen; Rabouw, Huib H; Züst, Roland; Hwang, Mihyun; V'Kovski, Philip; Stalder, Hanspeter; Marti, Sabrina; Habjan, Matthias; Cervantes-Barragan, Luisa; Elliot, Ruth; Karl, Nadja; Gaughan, Christina; van Kuppeveld, Frank J M; Silverman, Robert H; Keller, Markus; Ludewig, Burkhard; ... (2017). Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS pathogens, 13(2), e1006195. Public Library of Science 10.1371/journal.ppat.1006195

Pfänder, Stephanie; Vielle, Nathalie Jane; Ebert, Nadine; Steinmann, E; Alves, Marco; Thiel, Volker Earl (2017). Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization. Virus research, 228, pp. 58-60. Elsevier 10.1016/j.virusres.2016.11.025

Wu, Nai-Huei; Yang, Wei; Beineke, Andreas; Dijkman, Ronald; Matrosovich, Mikhail; Baumgärtner, Wolfgang; Thiel, Volker Earl; Valentin-Weigand, Peter; Meng, Fandan; Herrler, Georg (2016). The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells. Scientific Reports, 6(39668), p. 39668. Nature Publishing Group 10.1038/srep39668

Kaderali, Lars; Thiel, Volker Earl (2016). Systems biology of viral infection. Virus research, 218, p. 1. Elsevier 10.1016/j.virusres.2016.05.020

Kindler, Eveline Patricia; Thiel, Volker Earl (2016). SARS-CoV and IFN: Too Little, Too Late. Cell host & microbe, 19(2), pp. 139-141. Cell Press 10.1016/j.chom.2016.01.012

Kindler, Eveline Patricia; Thiel, Volker Earl; Weber, F (2016). Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response. Advances in virus research, 96, pp. 219-243. Elsevier 10.1016/bs.aivir.2016.08.006

Corman, Victor Max; Baldwin, Heather J; Tateno, Adriana Fumie; Zerbinati, Rodrigo Melim; Annan, Augustina; Owusu, Michael; Nkrumah, Evans Ewald; Maganga, Gael Darren; Oppong, Samuel; Adu-Sarkodie, Yaw; Vallo, Peter; da Silva Filho, Luiz Vicente Ribeiro Ferreira; Leroy, Eric M; Thiel, Volker Earl; van der Hoek, Lia; Poon, Leo L M; Tschapka, Marco; Drosten, Christian; Drexler, Jan Felix (2015). Evidence for an Ancestral Association of Human Coronavirus 229E with Bats. Journal of virology, 89(23), pp. 11858-11870. American Society for Microbiology 10.1128/JVI.01755-15

Lauber, C; Vieyres, G; Terczyńska-Dyla, E; Anggakusuma, X; Dijkman, Ronald; Gad, H H; Akhtar, H; Geffers, R; Vondran, F W R; Thiel, Volker Earl; Kaderali, L; Pietschmann, T; Hartmann, R (2015). Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells. Genes and immunity, 16(6), pp. 414-421. Nature Publishing Group 10.1038/gene.2015.23

Mielech, Anna M; Deng, Xufang; Chen, Yafang; Kindler, Eveline Patricia; Wheeler, Dorthea L; Mesecar, Andrew D; Thiel, Volker Earl; Perlman, Stanley; Baker, Susan C (2015). Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis. Journal of virology, 89(9), pp. 4907-4917. American Society for Microbiology 10.1128/JVI.00338-15

V'Kovski, Philip; Al-Mulla, Hawaa; Thiel, Volker Earl; Neuman, Benjamin W (2015). New insights on the role of paired membrane structures in coronavirus replication. Virus research, 202, pp. 33-40. Elsevier 10.1016/j.virusres.2014.12.021

Pas, Suzan D.; Patel, Pranav; Reusken, Chantal; Domingo, Cristina; Corman, Victor M.; Drosten, Christian; Dijkman, Ronald; Thiel, Volker Earl; Nowotny, Norbert; Koopmans, Marion P.G.; Niedrig, Matthias (2015). First international external quality assessment of molecular diagnostics for Mers-CoV. Journal of clinical virology, 69, pp. 81-85. Elsevier 10.1016/j.jcv.2015.05.022

Kindler, E; Thiel, Volker Earl (2014). To sense or not to sense viral RNA--essentials of coronavirus innate immune evasion. Current opinion in microbiology, 20, pp. 69-75. Elsevier 10.1016/j.mib.2014.05.005

Lundin, Anna; Dijkman, Ronald; Bergström, Tomas; Kann, Nina; Adamiak, Beata; Hannoun, Charles; Kindler, Eveline; Jónsdóttir, Hulda R; Muth, Doreen; Kint, Joeri; Forlenza, Maria; Müller, Marcel A; Drosten, Christian; Thiel, Volker Earl; Trybala, Edward (2014). Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS pathogens, 10(5), e1004166. Public Library of Science 10.1371/journal.ppat.1004166

Al-Mulla, Hawaa M N; Turrell, Lauren; Smith, Nicola M; Payne, Luke; Baliji, Surendranath; Züst, Roland; Thiel, Volker Earl; Baker, Susan C; Siddell, Stuart G; Neuman, Benjamin W (2014). Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. mBio, 5(2), e01107-e01113. American Society for Microbiology 10.1128/mBio.01107-13

Thiel, Volker Earl; Thiel, Heinz-Jürgen; Tekes, Gergely (2014). Tackling feline infectious peritonitis via reverse genetics. Bioengineered, 5(6), pp. 396-400. Taylor & Francis 10.4161/bioe.32133

Working Paper

V'kovski, Philip; Gerber, M; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga, Sophie Marie-Pierre; Simillion, Cedric André Marie; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (14 September 2018). Determination of host cell proteins constituting the molecular microenvironment of coronavirus replicase complexes by proximity-labeling (bioRxiv). Cold Spring Harbor Laboratory 10.1101/417907

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