Frey, Urs Peter

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Rüttimann, Céline; Nissen-Kratzert, Annika; Mostacci, Nadja; Künstle, Noëmi; Marten, Andrea; Gisler, Amanda; Bacher, Katharina; Yammine, Sophie; Steinberg, Ruth; Schulzke, Sven; Röösli, Martin; Latzin, Philipp; Hilty, Markus; Frey, Urs; Gorlanova, Olga (2023). Antibiotics in pregnancy influence nasal microbiome and respiratory morbidity in infancy. ERJ Open Research, 9(4) European Respiratory Society 10.1183/23120541.00225-2023


Gisler, Amanda; Eeftens, Marloes; de Hoogh, Kees; Vienneau, Danielle; Salem, Yasmin; Yammine, Sophie; Jakob, Julian; Gorlanova, Olga; Decrue, Fabienne; Gehrig, Regula; Frey, Urs; Latzin, Philipp; Fuchs, Oliver; Usemann, Jakob (2022). Pollen exposure is associated with risk of respiratory symptoms during the first year of life. Allergy, 77(12), pp. 3606-3616. Wiley-Blackwell 10.1111/all.15284


Gorlanova, Olga; Appenzeller, Rhea; Salem, Yasmin; Ramsey, Kathryn A.; Usemann, Jakob; Decrue, Fabienne; Kuehni, Claudia E.; Röösli, Martin; Latzin, Philipp; Fuchs, Oliver; Soti, Andras; Frey, Urs (2020). Effect of breastfeeding duration on lung function, respiratory symptoms and allergic diseases in school-age children. Pediatric pulmonology, 55(6), pp. 1448-1455. Wiley-Blackwell 10.1002/ppul.24733


Fouzas, Sotirios; Theodorakopoulos, Ilias; Delgado-Eckert, Edgar Wilfried; Latzin, Philipp; Frey, Urs Peter (2017). Breath-to-breath variability of exhaled CO2 as a marker of lung dysmaturity in infancy. Journal of applied physiology, 123(6), pp. 1563-1570. American Physiological Society 10.1152/japplphysiol.00372.2017

Nyilas, Sylvia Meryl; Bauman, Grzegorz; Sommer, Gregor; Stranzinger, Enno; Pusterla, Orso; Frey, Urs Peter; Korten, Insa Christina Severine; Singer, Florian; Casaulta Aebischer, Carmen; Bieri, Oliver; Latzin, Philipp (2017). Novel magnetic resonance technique for functional imaging of cystic fibrosis lung disease. European respiratory journal, 50(6) European Respiratory Society 10.1183/13993003.01464-2017

Kieninger, Elisabeth; Yammine, Sophie; Korten, Insa Christina Severine; Anagnostopoulou, Pinelopi; Singer, Florian; Frey, Urs Peter; Mornand, Anne; Zanolari, Maura; Rochat, Isabelle; Trachsel, Daniel; Müller-Suter, Dominik; Moeller, Alexander; Casaulta, Carmen; Latzin, Philipp (2017). Elevated lung clearance index in infants with cystic fibrosis shortly after birth. European respiratory journal, 50(5) European Respiratory Society 10.1183/13993003.00580-2017


Mika, Moana; Mack, Ines; Korten, Insa Christina Severine; Qi, Weihong; Aebi, Susanne; Frey, Urs Peter; Latzin, Philipp; Hilty, Markus (2015). Dynamics of the nasal microbiota in infancy: A prospective cohort study. Journal of allergy and clinical immunology, 135(4), 905-912.e11. Mosby 10.1016/j.jaci.2014.12.1909


Schmidt, Anne; Yammine, Sophie; Proietti, Elena; Frey, Urs Peter; Latzin, Philipp; Riedel, Thomas; Singer, Florian (2014). Validation of multiple-breath washout equipment for infants and young children. Pediatric pulmonology, 50(6), pp. 607-614. Wiley-Blackwell 10.1002/ppul.23010


Larsen, Pernille Stemann; Kamper-Jørgensen, Mads; Adamson, Ashley; Barros, Henrique; Bonde, Jens Peter; Brescianini, Sonia; Brophy, Sinead; Casas, Maribel; Charles, Marie-Aline; Devereux, Graham; Eggesbø, Merete; Fantini, Maria Pia; Frey, Urs; Gehring, Ulrike; Grazuleviciene, Regina; Henriksen, Tine Brink; Hertz-Picciotto, Irva; Heude, Barbara; Hryhorczuk, Daniel O; Inskip, Hazel; ... (2013). Pregnancy and birth cohort resources in europe: a large opportunity for aetiological child health research. PAEDIATRIC AND PERINATAL EPIDEMIOLOGY, 27(4), pp. 393-414. Wiley 10.1111/ppe.12060

Stern Meggers, Georgette; Latzin, Philipp; Röösli, Martin; Fuchs, Oliver; Proietti, Elena; Kuehni, Claudia; Frey, Urs Peter (2013). A prospective study of the impact of air pollution on respiratory symptoms and infections in infants. American journal of respiratory and critical care medicine, 187(12), pp. 1341-1348. New York, N.Y.: American Lung Association 10.1164/rccm.201211-2008OC


Fuchs, O; Latzin, P; Thamrin, C; Stern, G; Frischknecht, P; Singer, F; Kieninger, E; Proietti, E; Riedel, T; Frey, U (2011). Normative data for lung function and exhaled nitric oxide in unsedated healthy infants. European respiratory journal, 37(5), pp. 1208-1216. Sheffield, UK: European Respiratory Society 10.1183/09031936.00125510

Pramana, Isabelle A; Latzin, P; Schlapbach, L J; Hafen, G; Kuehni, C E; Nelle, M; Riedel, T; Frey, U (2011). Respiratory symptoms in preterm infants: burden of disease in the first year of life. European journal of medical research, 16(5), pp. 223-230. München: I. Holzapfel 10.1186/2047-783X-16-5-223

Kieninger, Elisabeth; Singer, Florian; Fuchs, Oliver; Abbas, Chiara; Frey, Urs; Regamey, Nicolas; Casaulta, Carmen; Latzin, Philipp (2011). Long-term course of lung clearance index between infancy and school-age in cystic fibrosis subjects. Journal of cystic fibrosis, 10(6), pp. 487-490. Amsterdam: Elsevier 10.1016/j.jcf.2011.07.006

Latzin, Philipp; Frey, Urs; Armann, Jakob; Kieninger, Elisabeth; Fuchs, Oliver; Röösli, Martin; Schaub, Bianca (2011). Exposure to moderate air pollution during late pregnancy and cord blood cytokine secretion in healthy neonates. PLoS ONE, 6(8), e23130. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0023130

Singer, Florian; Stern, Georgette; Thamrin, Cindy; Fuchs, Oliver; Riedel, Thomas; Gustafsson, Per; Frey, Urs; Latzin, Philipp (2011). Tidal volume single breath washout of two tracer gases--a practical and promising lung function test. PLoS ONE, 6(3), e17588. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0017588

Thamrin, Cindy; Nydegger, Regula; Stern, Georgette; Chanez, Pascal; Wenzel, Sally E; Watt, Rosemary A; FitzPatrick, Susan; Taylor, D Robin; Frey, Urs (2011). Associations between fluctuations in lung function and asthma control in two populations with differing asthma severity. Thorax, 66(12), pp. 1036-42. London: BMJ Publishing Group 10.1136/thx.2010.156489

Stern, Georgette; de Jongste, Johan; van der Valk, Ralf; Baraldi, Eugenio; Carraro, Silvia; Thamrin, Cindy; Frey, Urs (2011). Fluctuation phenotyping based on daily fraction of exhaled nitric oxide values in asthmatic children. Journal of allergy and clinical immunology, 128(2), pp. 293-300. St. Louis, Mo.: Mosby 10.1016/j.jaci.2011.03.010

Thamrin, Cindy; Zindel, Joel; Nydegger, Regula; Reddel, Helen K; Chanez, Pascal; Wenzel, Sally E; FitzPatrick, Susan; Watt, Rosemary A; Suki, Béla; Frey, Urs (2011). Predicting future risk of asthma exacerbations using individual conditional probabilities. Journal of allergy and clinical immunology, 127(6), 1494-502.e3. St. Louis, Mo.: Mosby 10.1016/j.jaci.2011.01.018


Amin, Samir D; Majumdar, Arnab; Frey, Urs; Suki, Bela (2010). MODELING THE DYNAMICS OF AIRWAY CONSTRICTION: EFFECTS OF AGONIST TRANSPORT AND BINDING. Journal of applied physiology, 109(2), pp. 553-563. Bethesda, Md.: American Physiological Society 10.1152/japplphysiol.01111.2009

Thamrin, Cindy; Stern, Georgette; Frey, Urs (2010). Fractals for physicians. Paediatric respiratory reviews, 11(2), pp. 123-31. London: Elsevier 10.1016/j.prrv.2010.02.001

Thamrin, Cindy; Taylor, D Robin; Jones, Stuart L; Suki, Béla; Frey, Urs (2010). Variability of lung function predicts loss of asthma control following withdrawal of inhaled corticosteroid treatment. Thorax, 65(5), pp. 403-8. London: BMJ Publishing Group 10.1136/thx.2009.129668

Hutten, Gerard J; van Eykern, Leo A; Latzin, Philipp; Thamrin, Cindy; van Aalderen, Wim M; Frey, Urs (2010). Respiratory muscle activity related to flow and lung volume in preterm infants compared with term infants. Pediatric research, 68(4), pp. 339-43. New York, N.Y.: Nature Publishing Group 10.1203/PDR.0b013e3181eeeaf4


Schlapbach, Luregn Jan; Latzin, Philipp; Regamey, Nicolas; Kuehni, Claudia E; Zwahlen, Marcel; Casaulta, Carmen; Aebi, Christoph; Frey, Urs (2009). Mannose-binding lectin cord blood levels and respiratory symptoms during infancy: a prospective birth cohort study. Pediatric allergy and immunology, 20(3), pp. 219-26. Oxford: Wiley-Blackwell 10.1111/j.1399-3038.2008.00782.x

Latzin, Philipp; Roth, Stefan; Thamrin, Cindy; Hutten, Gerard J; Pramana, Isabelle; Kuehni, Claudia E; Casaulta, Carmen; Nelle, Matthias; Riedel, Thomas; Frey, Urs (2009). Lung volume, breathing pattern and ventilation inhomogeneity in preterm and term infants. PLoS ONE, 4(2), e4635. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0004635

Thamrin, Cindy; Frey, Urs (2009). Complexity and respiratory growth: a developing story. Journal of applied physiology, 106(3), pp. 753-4. Bethesda, Md.: American Physiological Society 10.1152/japplphysiol.91588.2008

Latzin, P; Röösli, M; Huss, A; Kuehni, C E; Frey, U (2009). Air pollution during pregnancy and lung function in newborns: a birth cohort study. European respiratory journal, 33(3), pp. 594-603. Sheffield, UK: European Respiratory Society 10.1183/09031936.00084008

Thamrin, C; Stern, G; Strippoli, M-P F; Kuehni, C E; Suki, B; Taylor, D R; Frey, U (2009). Fluctuation analysis of lung function as a predictor of long-term response to beta2-agonists. European respiratory journal, 33(3), pp. 486-493. Sheffield, UK: European Respiratory Society 10.1183/09031936.00106208

Riedel, Thomas; Kyburz, Manuela; Latzin, Philipp; Thamrin, Cindy; Frey, Urs (2009). Regional and overall ventilation inhomogeneities in preterm and term-born infants. Intensive care medicine, 35(1), pp. 144-51. Berlin: Springer-Verlag 10.1007/s00134-008-1299-x

Frohna, John G; Frey, Urs (2009). Combination of epinephrine and dexamethasone may reduce hospitalization in children with bronchiolitis. Journal of pediatrics, 155(5), pp. 761-2. New York, N.Y.: Elsevier

Stern, Georgette; Beel, Julia; Suki, Béla; Silverman, Mike; Westaway, Jenny; Cernelc, Mateja; Baldwin, David; Frey, Urs (2009). Long-range correlations in rectal temperature fluctuations of healthy infants during maturation. PLoS ONE, 4(7), e6431. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0006431

Frey, Urs; von Mutius, Erika (2009). The challenge of managing wheezing in infants. New England journal of medicine NEJM, 360(20), pp. 2130-3. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMe0902242

Kraemer, R; Latzin, P; Pramana, I; Ballinari, P; Gallati, S; Frey, U (2009). Long-term gas exchange characteristics as marker of deterioration in patients with cystic fibrosis. Respiratory research, 10(106), [1-12]. London: BioMed Central 10.1186/1465-9921-10-106


Latzin, P; Hartl, D; Regamey, N; Frey, U; Schoeni, M H; Casaulta, C (2008). Comparison of serum markers for allergic bronchopulmonary aspergillosis in cystic fibrosis. European respiratory journal, 31(1), pp. 36-42. Sheffield, UK: European Respiratory Society 10.1183/09031936.00078107

Regamey, Nicolas; Kaiser, Laurent; Roiha, Hanna L; Deffernez, Christelle; Kuehni, Claudia E; Latzin, Philipp; Aebi, Christoph; Frey, Urs (2008). Viral etiology of acute respiratory infections with cough in infancy: a community-based birth cohort study. Pediatric infectious disease journal, 27(2), pp. 100-5. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/INF.0b013e31815922c8

Frey, U (2008). [Bronchial asthma in childhood. A survey]. Praxis - schweizerische Rundschau für Medizin, 97(19), pp. 1028-32. Bern: Huber

Frey, Urs; Suki, Béla (2008). Complexity of chronic asthma and chronic obstructive pulmonary disease: implications for risk assessment, and disease progression and control. Lancet, 372(9643), pp. 1088-99. London: Elsevier 10.1016/S0140-6736(08)61450-6

Minocchieri, Stefan; Burren, Juerg Martin; Bachmann, Marc Aurel; Stern, Georgette; Wildhaber, Johannes; Buob, Stefan; Schindel, Ralf; Kraemer, Richard; Frey, Urs Peter; Nelle, Mathias (2008). Development of the premature infant nose throat-model (PrINT-Model): an upper airway replica of a premature neonate for the study of aerosol delivery. Pediatric research, 64(2), pp. 141-6. New York, N.Y.: Nature Publishing Group 10.1203/PDR.0b013e318175dcfa

Brand, P L P; Baraldi, E; Bisgaard, H; Boner, A L; Castro-Rodriguez, J A; Custovic, A; de Blic, J; de Jongste, J C; Eber, E; Everard, M L; Frey, U; Gappa, M; Garcia-Marcos, L; Grigg, J; Lenney, W; Le Souëf, P; McKenzie, S; Merkus, P J F M; Midulla, F; Paton, J Y; ... (2008). Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. European respiratory journal, 32(4), pp. 1096-110. Sheffield, UK: European Respiratory Society 10.1183/09031936.00002108

Latzin, P; Frey, U (2008). Environmental exposure in relation to exhaled nitric oxide in newborns: is it all about timing? European respiratory journal, 32(2), pp. 252-4. Sheffield, UK: European Respiratory Society 10.1183/09031936.00073608

Hutten, Gerard J; van Eykern, Leo A; Latzin, Philipp; Kyburz, Manuela; van Aalderen, Wim M; Frey, Urs (2008). Relative impact of respiratory muscle activity on tidal flow and end expiratory volume in healthy neonates. Pediatric pulmonology, 43(9), pp. 882-891. New York, N.Y.: Wiley-Blackwell 10.1002/ppul.20874

Thamrin, C; Frey, U (2008). Effect of bacterial filter on measurement of interrupter resistance in preschool and school-aged children. Pediatric pulmonology, 43(8), pp. 781-7. Hoboken, N.J.: Wiley-Blackwell 10.1002/ppul.20865

Wäffler-Kammermann, Nathalie; Lacorcia, Ruth Stauffer; Wettstein, Markus; Radlinger, Lorenz; Frey, Urs (2008). A new standardized treadmill walking test requiring low motor skills in children aged 4-10 years. Pediatric pulmonology, 43(2), pp. 187-95. Hoboken, N.J.: Wiley-Blackwell 10.1002/ppul.20758


Roiha, H L; Kuehni, C E; Zanolari, M; Zwahlen, M; Baldwin, D N; Casaulta, C; Nelle, M; Frey, U (2007). Alterations of exhaled nitric oxide in pre-term infants with chronic lung disease. European respiratory journal, 29(2), pp. 251-8. Sheffield, UK: European Respiratory Society 10.1183/09031936.00016106

Stern, Georgette; Latzin, Philipp; Thamrin, Cindy; Frey, Urs (2007). How can we measure the impact of pollutants on respiratory function in very young children? Methodological aspects. Paediatric respiratory reviews, 8(4), pp. 299-304. London: Elsevier 10.1016/j.prrv.2007.07.008

Latzin, P; Sauteur, L; Thamrin, C; Schibler, A; Baldwin, D; Hutten, G J; Kyburz, M; Kraemer, R; Riedel, T; Frey, U (2007). Optimized temperature and deadspace correction improve analysis of multiple breath washout measurements by ultrasonic flowmeter in infants. Pediatric pulmonology, 42(10), pp. 888-97. Hoboken, N.J.: Wiley-Blackwell 10.1002/ppul.20674

Thamrin, C; Latzin, P; Sauteur, L; Riedel, T; Hall, G L; Frey, U (2007). Deadspace estimation from CO2 versus molar mass measurements in infants. Pediatric pulmonology, 42(10), pp. 920-7. Hoboken, N.J.: Wiley-Blackwell 10.1002/ppul.20683

Pachlopnik Schmid, JM; Kuehni, CE; Strippoli, MP; Roiha, HL; Pavlovic, R; Latzin, P; Gallati, S; Kraemer, R; Dahinden, C; Frey, U; Swiss, Pediatric Respiratory Research Group (2007). Maternal tobacco smoking and decreased leukocytes, including dendritic cells, in neonates. Pediatric research, 61(4), pp. 462-6. New York, N.Y.: Nature Publishing Group 10.1203/pdr.0b013e3180332d02

Regamey, N; Frey, U; Deffernez, C; Latzin, P; Kaiser, L; Swiss, Paediatric Respiratory Research Group (2007). Isolation of human bocavirus from Swiss infants with respiratory infections. Pediatric infectious disease journal, 26(2), pp. 177-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.inf.0000250623.43107.bc

Latzin, P; Frey, U; Roiha, HL; Baldwin, DN; Regamey, N; Strippoli, MP; Zwahlen, M; Kuehni, CE; Swiss, Paediatric Respiratory Research Group (2007). Prospectively assessed incidence, severity, and determinants of respiratory symptoms in the first year of life. Pediatric pulmonology, 42(1), pp. 41-50. Hoboken, N.J.: Wiley-Blackwell 10.1002/ppul.20542

Frey, Urs (2007). Predicting asthma control and exacerbations: chronic asthma as a complex dynamic model. Current opinion in immunology, 7(3), pp. 223-30. Kidlington, UK: Elsevier 10.1097/ACI.0b013e32810fd771


Gerritsen, Jorrit; Frey, Urs Peter (eds.) (2006). Respiratory Diseases in Infants and Children. European Respiratory Society Monograph: Vol. 11. Wakefield, UK: ERS Journals Ltd 10.1183/1025448x.ERM3706

Pfammatter, Jean-Pierre; Casaulta, Carmen; Pavlovic, Mladen; Berdat, Pascal A; Frey, Urs; Carrel, Thierry (2006). Important excess morbidity due to upper airway anomalies in the perioperative course in infant cardiac surgery. Annals of thoracic surgery, 81(3), pp. 1008-12. New York, N.Y.: Elsevier 10.1016/j.athoracsur.2005.09.015

Kraemer, Richard; Baldwin, David N; Ammann, Roland A; Frey, Urs; Gallati, Sabina (2006). Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis. Respiratory research, 7(1), p. 138. London: BioMed Central 10.1186/1465-9921-7-138

Latzin, Philipp; Kuehni, Claudia E; Baldwin, David N; Roiha, Hanna L; Casaulta, Carmen; Frey, Urs (2006). Elevated exhaled nitric oxide in newborns of atopic mothers precedes respiratory symptoms. American journal of respiratory and critical care medicine, 174(12), pp. 1292-8. New York, N.Y.: American Lung Association 10.1164/rccm.200606-782OC

Kondo, Tsutomu; Minocchieri, Stefan; Baldwin, David N; Nelle, Mathias; Frey, Urs (2006). Noninvasive monitoring of chest wall movement in infants using laser. Pediatric pulmonology, 41(10), pp. 985-92. Hoboken, N.J.: Wiley-Blackwell 10.1002/ppul.20482

Henschen, M; Stocks, J; Brookes, I; Frey, U (2006). New aspects of airway mechanics in pre-term infants. European respiratory journal, 27(5), pp. 913-20. Sheffield, UK: European Respiratory Society 10.1183/09031936.06.00036305

Baldwin, David N; Pillow, J Jane; Stocks, Janet; Frey, Urs (2006). Lung-function tests in neonates and infants with chronic lung disease: tidal breathing and respiratory control. Pediatric pulmonology, 41(5), pp. 391-419. Hoboken, N.J.: Wiley-Blackwell 10.1002/ppul.20400

Frey, U; Maksym, GN; Silverman, M; Suki, B (2006). New approaches to the understanding of complex chronic lung diseases. In: Respiratory Diseases in Infants and Children. European Respiratory Monograph. ERS Journals Ltd

Gappa, M; Stocks, J; Frey, U (2006). Assessing lung growth and function in infants and young children. In: Frey, U.; Gerritsen, J. (eds.) Respiratory Diseases in Infants and Children. European Respiratory Monograph 37 (pp. 22-40). ERS Journals Ltd


Regamey, N; Casaulta Aebischer, C; Frey, U (2005). [Acute asthma attacks in childhood]. Therapeutische Umschau, 62(8), pp. 539-42. Bern: Huber

Frey, Urs (2005). Forced oscillation technique in infants and young children. Paediatric respiratory reviews, 6(4), pp. 246-54. London: Elsevier 10.1016/j.prrv.2006.04.02

Kaiser, Laurent; Regamey, Nicolas; Roiha, Hanna; Deffernez, Christelle; Frey, Urs (2005). Human coronavirus NL63 associated with lower respiratory tract symptoms in early life. Pediatric infectious disease journal, 24(11), pp. 1015-7. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.inf.0000183773.80217.12

Frey, Urs; Brodbeck, Tanja; Majumdar, Arnab; Taylor, D Robin; Town, G Ian; Silverman, Michael; Suki, Béla (2005). Risk of severe asthma episodes predicted from fluctuation analysis of airway function. Nature, 438(7068), pp. 667-70. London: Macmillan Journals Ltd. 10.1038/nature04176

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