Paradisi, Francesca

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Benitez Mateos, Ana I.; Paradisi, Francesca (2022). Sustainable flow‐synthesis of (bulky)nucleoside drugs by a novel and highly stable nucleoside phosphorylase immobilized on reusable supports. ChemSusChem, 15(1), e202102030. Wiley-VCH 10.1002/cssc.202102030


Heckmann, Christian M.; Paradisi, Francesca (2021). GPhos Ligand Enables Production of Chiral N ‐Arylamines in a Telescoped Transaminase‐Buchwald‐Hartwig Amination Cascade in the Presence of Excess Amine Donor. Chemistry - a European journal, 27(67), pp. 16616-16620. Wiley-VCH 10.1002/chem.202103472

Marchini, Valentina; Benítez Mateos, Ana I.; Roura Padrosa, David; Paradisi, Francesca (2021). Fusion of Glutamate Dehydrogenase and Formate Dehydrogenase Yields a Bifunctional Efficient Biocatalyst for the Continuous Removal of Ammonia. Frontiers in Catalysis, 1 Frontiers Media 10.3389/fctls.2021.790461

Montanari, Ulisse; Cocchi, Davide; Brugo, Tommaso Maria; Pollicino, Antonino; Taresco, Vincenzo; Romero Fernandez, Maria; Moore, Jonathan C.; Sagnelli, Domenico; Paradisi, Francesca; Zucchelli, Andrea; Howdle, Steven M.; Gualandi, Chiara (2021). Functionalisable Epoxy-rich Electrospun Fibres Based on Renewable Terpene for Multi-Purpose Applications. Polymers, 13(11), p. 1804. MDPI 10.3390/polym13111804

Roura Padrosa, David; Nisar, Zoya; Paradisi, Francesca (2021). Efficient Amino Donor Recycling in Amination Reactions: Development of a New Alanine Dehydrogenase in Continuous Flow and Dialysis Membrane Reactors. Catalysts, 11(4), p. 520. MDPI 10.3390/catal11040520

Heckmann, Christian M.; Dominguez, Beatriz; Paradisi, Francesca (2021). Enantio-Complementary Continuous-Flow Synthesis of 2-Aminobutane Using Covalently Immobilized Transaminases. ACS sustainable chemistry & engineering, 9(11), pp. 4122-4129. American Chemical Society 10.1021/acssuschemeng.0c09075

Roura Padrosa, David; Marchini, Valentina; Paradisi, Francesca (2021). CapiPy: python based GUI-application to assist in protein immobilization (In Press). Bioinformatics Oxford University Press 10.1093/bioinformatics/btab030

Delgado, Lidia; Heckmann, Christian M.; Di Pisa, Flavio; Gourlay, Louise; Paradisi, Francesca (2021). Release of Soybean Isoflavones by Using a β‐Glucosidase from Alicyclobacillus herbarius. ChemBioChem, 22(7), pp. 1223-1231. Wiley-VCH 10.1002/cbic.202000688

Delgado, Lidia; Heckmann, Christian M.; De Benedetti, Stefano; Nardini, Marco; Gourlay, Louise J.; Paradisi, Francesca (2021). Producing natural vanilla extract from green vanilla beans using a β-glucosidase from Alicyclobacillus acidiphilus. Journal of biotechnology, 329, pp. 21-28. Elsevier 10.1016/j.jbiotec.2021.01.017

Benítez-Mateos, Ana I.; Contente, Martina L.; Roura Padrosa, David; Paradisi, Francesca (2021). Flow biocatalysis 101: design, development and applications. Reaction chemistry & engineering, 6(4), pp. 599-611. Royal Society of Chemistry 10.1039/D0RE00483A

Romero-Fernandez, Maria; Paradisi, Francesca (2021). Biocatalytic access to betazole by one-pot multienzymatic system in continuous flow. Green chemistry, 23(12), pp. 4594-4603. Royal Society of Chemistry 10.1039/D1GC01095F

Benítez-Mateos, Ana I.; Bertella, Stefania; Behaghel de Bueren, Jean; Luterbacher, Jeremy S.; Paradisi, Francesca (2021). Dual Valorization of Lignin as a Versatile and Renewable Matrix for Enzyme Immobilization and (Flow) Bioprocess Engineering. ChemSusChem, 14(15), pp. 3198-3207. Wiley-VCH 10.1002/cssc.202100926

Lenzen, Karst; Planchestainer, Matteo; Feller, Isabelle; Roura Padrosa, David; Paradisi, Francesca; Albrecht, Martin (2021). Minimalistic peptidic scaffolds harbouring an artificial carbene-containing amino acid modulate reductase activity. Chemical communications, 57(72), pp. 9068-9071. Royal Society of Chemistry 10.1039/D1CC03158A

Paradisi, Francesca; Poppe, László (2021). Continuous-flow biocatalysis with enzymes and cells. In: Darvas, Ferenc; Dormán, György; Hessel, Volker; Ley, Steven V. (eds.) Volume 2 Flow Chemistry – Applications. De Gruyter Textbook (pp. 277-312). De Gruyter 10.1515/9783110693690-010


Planchestainer, Matteo; McMaster, Jonathan; Schulz, Christine; Paradisi, Francesca; Albrecht, Martin (2020). Carbene‐Induced Rescue of Catalytic Activity in Deactivated Nitrite Reductase Mutant. Chemistry - a European journal, 26(66), pp. 15206-15211. Wiley-VCH 10.1002/chem.202002444

Hegarty, Eimear; Paradisi, Francesca (2020). Implementation of Biocatalysis in Continuous Flow for the Synthesis of Small Cyclic Amines. CHIMIA, 74(11), pp. 890-894. Schweizerische Chemische Gesellschaft 10.2533/chimia.2020.890

Contente, Martina L.; Fiore, Noemi; Cannazza, Pietro; Roura Padrosa, David; Molinari, Francesco; Gourlay, Louise; Paradisi, Francesca (2020). Uncommon overoxidative catalytic activity in a new halo‐tolerant alcohol dehydrogenase. ChemCatChem, 12(22), pp. 5679-5685. WILEY-VCH 10.1002/cctc.202001112

Heckmann, Christian M.; Gourlay, Louise J.; Dominguez, Beatriz; Paradisi, Francesca (2020). An (R)-Selective Transaminase From Thermomyces stellatus: Stabilizing the Tetrameric Form. Frontiers in Bioengineering and Biotechnology, 8(707) Frontiers Media 10.3389/fbioe.2020.00707

Roura Padrosa, David; Benítez-Mateos, Ana I.; Calvey, Liam; Paradisi, Francesca (2020). Cell-free biocatalytic syntheses of L-pipecolic acid: a dual strategy approach and process intensification in flow. Green chemistry, 22(16), pp. 5310-5316. Royal Society of Chemistry 10.1039/D0GC01817A

Paradisi, Francesca (3 March 2020). Progress in Flow Biocatalysts: Multi-enzyme Cascades and Implementation (Unpublished). In: Flow Chemistry Europe 2020.

Paradisi, Francesca (17 February 2020). Versatility of transaminases in flow biocatalysis (Unpublished). In: Amine Biocatalysis 4.0.

ul Haque, R; Allers, T; Paradisi, Francesca (2020). Haloferax volcanii for biotechnology applications: challenges, current state and perspectives. Applied microbiology and biotechnology, 104(4), pp. 1371-1382. Springer 10.1007/s00253-019-10314-2

Romero Fernández, María; Paradisi, Francesca (2020). General overview on immobilisation techniques of enzymes for biocatalysis. In: Benaglia, Maurizio; Puglisi, Alessandra (eds.) Catalyst Immobilization: Methods and Applications (pp. 409-436). Wiley-VCH

Contente, Martina Letizia; Tamborini, Lucia; Molinari, Francesco; Paradisi, Francesca (2020). Aromas flow: eco-friendly, continuous, and scalable preparation of flavour esters. Journal of flow chemistry, 10(1), pp. 235-240. Springer 10.1007/s41981-019-00063-8

Almulhim, Nouarh; Moody, Nicholas R.; Paradisi, Francesca (2020). Engineering novel S-glycosidase activity into extremo-adapted β-glucosidase by rational design. Applied microbiology and biotechnology, 104(10), pp. 4407-4415. Springer 10.1007/s00253-020-10582-3

Delgado, Lidia; Parker, Mango; Fisk, Ian; Paradisi, Francesca (2020). Performance of the extremophilic enzyme BglA in the hydrolysis of two aroma glucosides in a range of model and real wines and juices. Food Chemistry, 323, p. 126825. Elsevier 10.1016/j.foodchem.2020.126825

Romero-Fernández, María; Paradisi, Francesca (2020). Protein immobilization technology for flow biocatalysis. Current opinion in chemical biology, 55, pp. 1-8. Elsevier 10.1016/j.cbpa.2019.11.008

Heckmann, Christian M.; Paradisi, Francesca (2020). Looking back: A short history of the discovery of enzymes and how they became powerful chemical tools. ChemCatChem, 12(24), pp. 6082-6102. WILEY-VCH 10.1002/cctc.202001107

Contente, Martina L.; Roura Padrosa, David; Molinari, Francesco; Paradisi, Francesca (2020). A strategic Ser/Cys exchange in the catalytic triad unlocks an acyltransferase-mediated synthesis of thioesters and tertiary amides. Nature catalysis, 3(12), pp. 1020-1026. Nature Publishing Group 10.1038/s41929-020-00539-0


Planchestainer, Matteo; Lenzen, Karst Eelco; Paradisi, Francesca; Albrecht, Martin (6 December 2019). Installing a metal active centre in peptide scaffolds thought an unnatural NHC-amino acid (Unpublished). In: CSCB Symposium. Dublin, Ireland. 6.12.2019.

Paradisi, Francesca (6 December 2019). Heterogenous biocatalysis in continuous flow systems as a new approach to synthetic chemistry (Unpublished). In: Recent Advances in Synthesis and Chemical Biology XVIII. Dublin, Ireland.

Paradisi, Francesca (21 November 2019). Biocatalysis and Flow Technology (Unpublished). In: Swiss Industrial Biocatalysis Consortium 2019.

Roura Padrosa, David; Alaux, Raphael; Smith, Phillip; Dreveny, Ingrid; López-Gallego, Fernando; Paradisi, Francesca (2019). Enhancing PLP-Binding Capacity of Class-III ω-Transaminase by Single Residue Substitution. Frontiers in Bioengineering and Biotechnology, 7(282) Frontiers Media 10.3389/fbioe.2019.00282

Paradisi, Francesca (21 June 2019). Continuous Flow biocatalysis for highly sustainable and versatile syntheses (Unpublished). In: 71st Irish Universities Chemistry Research Colloquium.

Planchestainer, Matteo; Ségaud, Nathalie Sylvie Laetitia; Paradisi, Francesca; Albrecht, Martin (14 June 2019). Carbene- rather than Nitrogen-metal bonding mode alters metallo-enzymes features (Unpublished). In: NoNoMeCat Symposium. Basel, Switzerland. 14.6.2019.

Planchestainer, Matteo; Lenzen, Karst Eelco; Paradisi, Francesca; Albrecht, Martin (9 June 2019). Installing a metal active centre in peptide scaffolds thought an unnatural NHC-amino acid (Unpublished). In: Swiss Chemical Society Fall Meeting 2019. Zurich, Switzerland. 6.9.2019.

Contente, Martina Letizia; Farris, Stefano; Tamborini, Lucia; Molinari, Francesco; Paradisi, Francesca (2019). Flow-based enzymatic synthesis of melatonin and other high value tryptamine derivatives: a five-minute intensified process. Green chemistry, 21(12), pp. 3263-3266. Royal Society of Chemistry 10.1039/C9GC01374A

Paradisi, Francesca (19 May 2019). Sustainable Catalysis: enzyme-mediated synthesis of high value chemicals and pharmaceuticals in Flow Reactors (Unpublished). In: 5th IMTB. Cavtat, Croatia.

Planchestainer, Matteo; Hegarty, Eimear; Heckmann, Christian M.; Gourlay, Louise J.; Paradisi, Francesca (2019). Widely applicable background depletion step enables transaminase evolution through solid-phase screening. Chemical Science, 10(23), pp. 5952-5958. The Royal Society of Chemistry 10.1039/C8SC05712E

Contente Martina Letizia, Contente; Paradisi, Francesca (2019). Transaminase-catalyzed continous synthesis of biogenic aldehydes. ChemBioChem, 20(22), pp. 2830-2833. Wiley-VCH 10.1002/cbic.201900356

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