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Number of items at this level: 123.

2024

Zaugg, Jonas; Lopez-Tello, Jorge; Musial, Barbara; Vaughan, Owen R; Fowden, Abigail L; Albrecht, Christiane; Sferruzzi-Perri, Amanda N (2024). Obesogenic diet in pregnancy disrupts placental iron handling and ferroptosis and stress signalling in association with fetal growth alterations. Cellular and molecular life sciences : CMLS, 81(151) Springer 10.1007/s00018-024-05192-5

Fuenzalida, Barbara; Yañez, Maria Jose; Mueller, Martin; Mistry, Hiten D; Leiva, Andrea; Albrecht, Christiane (2024). Evidence for hypoxia-induced dysregulated cholesterol homeostasis in preeclampsia: Insights into the mechanisms from human placental cells and tissues. FASEB journal, 38(2) Federation of American Societies for Experimental Biology 10.1096/fj.202301708RR

Ekundayo, Babatunde; Arullampalam, Prakash; Gerber, Christian E.; Hämmerli, Anne-Flore; Guichard, Sabrina; Boukenna, Mey; Ross, Daniela; Lochner, Martin; Rougier, Jean-Sébastien; Stahlberg, Henning; Abriel, Hugues; Ni, Dongchun (23 January 2024). Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4 (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2024.01.22.576650

Zaugg, Jonas; Albrecht, Christiane (2024). Assessment of Placental Sodium-Independent Leucine Uptake and Transfer in Trophoblast Cells. Methods in molecular biology, 2728, pp. 105-121. Springer 10.1007/978-1-0716-3495-0_9

2023

Kucharczyk, Patrycja; Albano, Giuseppe; Deisl, Christine; Ho, Manh Tin; Bargagli, Matteo; Anderegg, Manuel; Wueest, Stephan; Konrad, Daniel; Fuster, Daniel G. (2023). Thiazides Attenuate Insulin Secretion Through Inhibition of Mitochondrial Carbonic Anhydrase 5b in β-islet Cells in Mice. Journal of the American Society of Nephrology JASN, 34(7), pp. 1179-1190. American Society of Nephrology 10.1681/ASN.0000000000000122

2022

Zaugg, Jonas; Pujol Giménez, Jonai; Cabra, Romina Silvia; Hofstetter, Wilhelm; Hediger, Matthias; Albrecht, Christiane (2022). New Insights into the Physiology of Iron Transport: An Interdisciplinary Approach. CHIMIA, 76(12), pp. 996-1004. 10.2533/chimia.2022.996

Rossetti, Valentina; Abriel, Hugues (2022). The NCCR TransCure: An Incubator for Interdisciplinary Research. CHIMIA, 76(12), pp. 992-995. Schweizerische Chemische Gesellschaft 10.2533/chimia.2022.992

Schneider, Henning; Albrecht, Christiane; Ahmed, Mahmoud S; Broekhuizen, Michelle; Aengenheister, Leonie; Buerki-Thurnherr, Tina; Danser, A H Jan; Gil, Sophie; Hansson, Stefan R; Greupink, Rick; Lewis, Rohan M; Markert, Udo R; Mathiesen, Line; Powles-Glover, Nicola; Wadsack, Christian; Brownbill, Paul (2022). Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability. Placenta, 126, pp. 83-89. Elsevier 10.1016/j.placenta.2022.05.003

Fuenzalida, Barbara; Kallol, Sampada; Zaugg, Jonas; Müller, Martin; Mistry, Hiten D; Gutierrez, Jaime; Leiva, Andrea; Albrecht, Christiane (2022). Primary Human Trophoblasts Mimic the Preeclampsia Phenotype after Acute Hypoxia-Reoxygenation Insult. Cells, 11(12) MDPI 10.3390/cells11121898

Anderegg, Manuel A; Gyimesi, Gergely; Ho, Manh Tin; Hediger, Matthias A; Fuster, Daniel G (2022). The Less Well-Known Little Brothers: The SLC9B/NHA Sodium Proton Exchanger Subfamily—Structure, Function, Regulation and Potential Drug-Target Approaches. Frontiers in physiology, 13, p. 898508. Frontiers Research Foundation 10.3389/fphys.2022.898508

Kucharczyk, Patrycja; Albano, Giuseppe; Deisl, Christine; Wueest, Stephan; Konrad, Daniel; Fuster, Daniel G (26 March 2022). Thiazides induce glucose intolerance through inhibition of mitochondrial carbonic anhydrase 5b in β-cells (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2022.03.23.485566

Andrieu, Thomas; Chicca, Andrea; Pellegata, Daniele; Bersinger, Nick A.; Imboden, Sara; Nirgianakis, Konstantinos; Gertsch, Jürg; Mueller, Michael D. (2022). Association of endocannabinoids with pain in endometriosis. Pain, 163(1), pp. 193-203. Elsevier 10.1097/j.pain.0000000000002333

Karahoda, Rona; Zaugg, Jonas; Fuenzalida, Barbara; Kallol, Sampada; Moser-Haessig, Ruedi; Staud, Frantisek; Albrecht, Christiane (2022). Trophoblast Differentiation Affects Crucial Nutritive Functions of Placental Membrane Transporters. Frontiers in cell and developmental biology, 10, p. 820286. Frontiers 10.3389/fcell.2022.820286

Stauffer, Mirko; Jeckelmann, Jean-Marc; Ilgü, Hüseyin; Ucurum, Zöhre; Boggavarapu, Rajendra; Fotiadis, Dimitrios (2022). Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Communications chemistry, 5(1) Springer Nature 10.1038/s42004-022-00636-0

2021

Shrestha, Neeta; Gall, Flavio Max; Mathieu, Cyrille; Hierweger, Melanie Michaela; Brügger, Melanie; Alves, Marco P.; Vesin, Jonathan; Banfi, Damiano; Kalbermatter, David; Horvat, Branka; Chambon, Marc; Turcatti, Gerardo; Fotiadis, Dimitrios; Riedl, Rainer; Plattet, Philippe (2021). Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier. mBio, 12(6), e0262121. American Society for Microbiology 10.1128/mBio.02621-21

Shahnawaz, Saira; Nawaz, Usman Shah; Zaugg, Jonas; Hussain, Ghulam; Malik, Nadia; Dogar, Muhammad Zahoor-Ul-Hassan; Malik, Shoaib Ahmad; Albrecht, Christiane (2021). Dysregulated Autophagy Leads to Oxidative Stress and Aberrant Expression of ABC Transporters in Women with Early Miscarriage. Antioxidants, 10(11) MDPI 10.3390/antiox10111742

Zaugg, Jonas; Ziegler, Fabian; Nuoffer, Jean-Marc; Moser-Hässig, Ruedi; Albrecht, Christiane (2021). Counter-directed leucine gradient promotes amino acid transfer across the human placenta. The journal of nutritional biochemistry, 96, p. 108760. Elsevier 10.1016/j.jnutbio.2021.108760

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Kalbermatter, David; Ucurum, Zöhre; Lemmin, Thomas; Fotiadis, Dimitrios (2021). High-resolution structure of the amino acid transporter AdiC reveals insights into the role of water molecules and networks in oligomerization and substrate binding. BMC biology, 19(1), p. 179. BioMed Central 10.1186/s12915-021-01102-4

Kantipudi, Satish; Harder, Daniel; Bonetti, Sara; Fotiadis, Dimitrios; Jeckelmann, Jean-Marc (2021). Pichia pastoris and the Recombinant Human Heterodimeric Amino Acid Transporter 4F2hc-LAT1: From Clone Selection to Pure Protein. Methods and protocols, 4(3) MDPI AG 10.3390/mps4030051

Arullampalam, Prakash; Preti, Barbara; Ross, Daniela; Lochner, Martin; Rougier, Jean-Sébastien; Abriel, Hugues (2021). Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors. Frontiers in Pharmacology, 12 Frontiers 10.3389/fphar.2021.712354

Hirschi, Stephan; Kalbermatter, David; Ucurum, Zöhre; Lemmin, Thomas; Fotiadis, Dimitrios (2021). Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin. Nature communications, 12(1), p. 4107. Nature Publishing Group 10.1038/s41467-021-24429-6

Arullampalam, Prakash; Preti, Barbara; Ross-Kaschitza, Daniela; Lochner, Martin; Rougier, Jean-Sébastien; Abriel, Hugues (2 June 2021). Species-specific effects of cation channel TRPM4 small-molecule inhibitors (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.06.01.446517

Traversi, Florian; Stooss, Amandine; Dettmer, Matthias S.; Charles, Roch-Philippe (2021). BRAFV600E Overrides NOTCH Signaling in Thyroid Cancer. Thyroid, 31(5), pp. 787-799. Mary Ann Liebert 10.1089/thy.2019.0595

Reynoso-Moreno, Ines; Tietz, Silvia; Vallini, Erika; Engelhardt, Britta; Gertsch, Jürg; Chicca, Andrea (2021). Selective Endocannabinoid Reuptake Inhibitor WOBE437 Reduces Disease Progression in a Mouse Model of Multiple Sclerosis. ACS pharmacology & translational science, 4(2), pp. 765-779. ACS Publications 10.1021/acsptsci.0c00214

Schneider, Henning; Brownbill, Paul; Albrecht, Christiane (2021). Ex vivo dual perfusion of an isolated cotyledon of human placenta: History and future challenges. Placenta, 107, pp. 8-12. Elsevier 10.1016/j.placenta.2021.02.017

Ozhathil, Lijo Cherian; Rougier, Jean-Sébastien; Arullampalam, Prakash; Essers, Maria C.; Ross-Kaschitza, Daniela; Abriel, Hugues (2021). Deletion of Trpm4 Alters the Function of the Nav1.5 Channel in Murine Cardiac Myocytes. International journal of molecular sciences, 22(7) MDPI 10.3390/ijms22073401

Verouti, Sophia N; Lambert, Delphine; Mathis, Déborah; Pathare, Ganesh; Escher, Geneviève; Vogt, Bruno; Fuster, Daniel G. (2021). The solute carrier SLC16A12 is critical for creatine and guanidinoacetate handling in the kidney. American journal of physiology. Renal physiology, 320(3), F351-F358. American Physiological Society 10.1152/ajprenal.00475.2020

Hu, Yaopeng; Ross Kaschitza, Daniela; Essers, Maria; Arullampalam, Prakash; Fujita, Takayuki; Abriel, Hugues; Inoue, Ryuji (2021). Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation. Pflügers Archiv : European journal of physiology, 473(3), pp. 507-519. Springer 10.1007/s00424-020-02507-w

Karahoda, Rona; Kallol, Sampada; Groessl, Michael; Ontsouka, Edgar; Anderle, Pascale; Fluck, Christa; Staud, Frantisek; Albrecht, Christiane (2021). Revisiting Steroidogenic Pathways in the Human Placenta and Primary Human Trophoblast Cells. International journal of molecular sciences, 22(4) MDPI 10.3390/ijms22041704

Borgström, Anna; Peinelt, Christine; Stoklosa, Paulina (2021). TRPM4 in Cancer-A New Potential Drug Target. Biomolecules, 11(2) MDPI 10.3390/biom11020229

Fuenzalida, Bárbara; Kallol, Sampada; Lüthi, Michael; Albrecht, Christiane; Leiva, Andrea (2021). The polarized localization of lipoprotein receptors and cholesterol transporters in the syncytiotrophoblast of the placenta is reproducible in a monolayer of primary human trophoblasts. Placenta, 105, pp. 50-60. Elsevier 10.1016/j.placenta.2021.01.019

Shrestha, Neeta; Gall, Flavio M; Vesin, Jonathan; Chambon, Marc; Turcatti, Gerardo; Fotiadis, Dimitrios; Riedl, Rainer; Plattet, Philippe (2021). Antiviral Screen against Canine Distemper Virus-Induced Membrane Fusion Activity. Viruses, 13(1) MDPI 10.3390/v13010128

Granchi, Carlotta; Bononi, Giulia; Ferrisi, Rebecca; Gori, Eleonora; Mantini, Giulia; Glasmacher, Sandra; Poli, Giulio; Palazzolo, Stefano; Caligiuri, Isabella; Rizzolio, Flavio; Canzonieri, Vincenzo; Perin, Tiziana; Gertsch, Jürg; Sodi, Andrea; Giovannetti, Elisa; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano; Chicca, Andrea (2021). Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. European journal of medicinal chemistry, 209, p. 112857. Elsevier 10.1016/j.ejmech.2020.112857

Bosshart, Patrick D.; Charles, Roch-Philippe; Garibsingh, Rachel-Ann A; Schlessinger, Avner; Fotiadis, Dimitrios (2021). SLC16 Family: From Atomic Structure to Human Disease. Trends in biochemical sciences, 46(1), pp. 28-40. Elsevier Current Trends 10.1016/j.tibs.2020.07.005

Anderegg, Manuel A.; Albano, Giuseppe; Hanke, Daniela; Deisl, Christine; Uehlinger, Dominik E.; Brandt, Simone; Bhardwaj, Rajesh; Hediger, Matthias A.; Fuster, Daniel G. (2021). The sodium/proton exchanger NHA2 regulates blood pressure through a WNK4-NCC dependent pathway in the kidney. Kidney international, 99(2), pp. 350-363. Elsevier 10.1016/j.kint.2020.08.023

Bosshart, Patrick D.; Kalbermatter, David; Bonetti, Sara; Fotiadis, Dimitrios (2021). The making of a potent L-lactate transport inhibitor. Communications chemistry, 4(1) Springer Nature 10.1038/s42004-021-00564-5

2020

Arena, Chiara; Gado, Francesca; Di Cesare Mannelli, Lorenzo; Cervetto, Chiara; Carpi, Sara; Reynoso-Moreno, Ines; Polini, Beatrice; Vallini, Erika; Chicca, Stefano; Lucarini, Elena; Bertini, Simone; D'Andrea, Felicia; Digiacomo, Maria; Poli, Giulio; Tuccinardi, Tiziano; Macchia, Marco; Gertsch, Jürg; Marcoli, Manuela; Nieri, Paola; Ghelardini, Carla; ... (2020). The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis. European journal of medicinal chemistry, 208, p. 112858. Elsevier 10.1016/j.ejmech.2020.112858

Wang, Zizun; Vermij, Sarah H.; Sottas, Valentin; Shestak, Anna; Ross-Kaschitza, Daniela; Zaklyazminskaya, Elena V; Hudmon, Andy; Pitt, Geoffrey S; Rougier, Jean-Sébastien; Abriel, Hugues (2020). Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5. Channels, 14(1), pp. 268-286. Taylor & Francis 10.1080/19336950.2020.1805999

Miller, Sally; Daily, Laura; Dharla, Vijai; Gertsch, Jürg; Malamas, Michael S; Ojima, Iwao; Kaczocha, Martin; Ogasawara, Daisuke; Straiker, Alex (2020). Endocannabinoid metabolism and transport as targets to regulate intraocular pressure. Experimental eye research, 201, p. 108266. Elsevier 10.1016/j.exer.2020.108266

Zaugg, Jonas; Huang, Xiao; Ziegler, Fabian; Rubin, Matthias; Graff, Julien; Müller, Jennifer; Moser-Hässig, Ruedi; Powell, Theresa; Gertsch, Jürg; Altmann, Karl-Heinz; Albrecht, Christiane (2020). Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno-foetal amino acid transport. Journal of cellular and molecular medicine, 24(21), pp. 12681-12693. Wiley 10.1111/jcmm.15840

Kantipudi, Satish; Jeckelmann, Jean-Marc; Ucurum, Zöhre; Bosshart, Patrick D.; Fotiadis, Dimitrios (2020). The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2. International journal of molecular sciences, 21(20) MDPI 10.3390/ijms21207573

Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2020). Sub-Nanometer Cryo-EM Density Map of the Human Heterodimeric Amino Acid Transporter 4F2hc-LAT2. International journal of molecular sciences, 21(19) MDPI 10.3390/ijms21197094

Guha, Sujay; Calarco, Serafina; Gachet, M. Salomé; Gertsch, Jürg (2020). Juniperonic Acid Biosynthesis is Essential in Caenorhabditis Elegans Lacking Δ6 Desaturase (fat-3) and Generates New ω-3 Endocannabinoids. Cells, 9(9) MDPI 10.3390/cells9092127

Stauffer, Mirko; Hirschi, Stephan; Ucurum, Zöhre; Harder, Daniel; Schlesinger, Ramona; Fotiadis, Dimitrios (2020). Engineering and Production of the Light-Driven Proton Pump Bacteriorhodopsin in 2D Crystals for Basic Research and Applied Technologies. Methods and protocols, 3(3) MDPI AG 10.3390/mps3030051

Stoklosa, Paulina; Probst, Daniel; Reymond, Jean-Louis; Peinelt, Christine (2020). The name tells the story: Two-pore channels. Cell calcium, 89, p. 102215. Elsevier 10.1016/j.ceca.2020.102215

Kallol, Sampada; Albrecht, Christiane (2020). Materno-fetal cholesterol transport during pregnancy. Biochemical Society transactions, 48(3), pp. 775-786. Portland Press 10.1042/BST20190129

Zaugg, Jonas; Melhem, Hassan; Huang, Xiao; Wegner, Malgorzata; Baumann, Marc; Surbek, Daniel; Körner, Meike; Albrecht, Christiane (2020). Gestational diabetes mellitus affects placental iron homeostasis: Mechanism and clinical implications. FASEB journal, 34(6), pp. 7311-7329. Federation of American Societies for Experimental Biology 10.1096/fj.201903054R

Gyimesi, Gergely; Albano, Giuseppe; Fuster, Daniel G.; Hediger, Matthias A.; Pujol-Giménez, Jonai (2020). Correction: Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2). Journal of biological chemistry, 295(13), p. 4369. American Society for Biochemistry and Molecular Biology 10.1074/jbc.AAC120.013245

Fuenzalida, Bárbara; Cantin, Claudette; Kallol, Sampada; Carvajal, Lorena; Pastén, Valentina; Contreras-Duarte, Susana; Albrecht, Christiane; Gutierrez, Jaime; Leiva, Andrea (2020). Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia. Scientific Reports, 10(1), p. 5264. Nature Publishing Group 10.1038/s41598-020-61629-4

Stoklosa, Paulina; Borgström, Anna; Kappel, Sven; Peinelt, Christine (2020). TRP Channels in Digestive Tract Cancers. International journal of molecular sciences, 21(5) MDPI 10.3390/ijms21051877

Kucharava, Krystsina; Brand, Yves; Albano, Giuseppe; Sekulic-Jablanovic, Marijana; Glutz, Andrea; Xian, Xunde; Herz, Joachim; Bodmer, Daniel; Fuster, Daniel G.; Petkovic, Vesna (2020). Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway. Scientific reports, 10(1), p. 3609. Springer Nature 10.1038/s41598-020-60262-5

Gado, Francesca; Arena, Chiara; Fauci, Cristiana La; Reynoso-Moreno, Ines; Bertini, Simone; Digiacomo, Maria; Meini, Serena; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano; Gertsch, Jürg; Chicca, Andrea; Manera, Clementina (2020). Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system. Bioorganic chemistry, 94, p. 103353. Elsevier 10.1016/j.bioorg.2019.103353

Karahoda, Rona; Abad, Cilia; Horackova, Hana; Kastner, Petr; Zaugg, Jonas; Cerveny, Lukas; Kucera, Radim; Albrecht, Christiane; Staud, Frantisek (2020). Dynamics of Tryptophan Metabolic Pathways in Human Placenta and Placental-Derived Cells: Effect of Gestation Age and Trophoblast Differentiation. Frontiers in cell and developmental biology, 8, p. 574034. Frontiers 10.3389/fcell.2020.574034

Jeckelmann, Jean-Marc; Ilgü, Hüseyin; Bosshart, Patrick D.; Fotiadis, Dimitrios José (2020). A procedure and double-chambered device for macromolecular crystal flash-cooling in different cryogenic liquids. PLoS ONE, 15(9), e0239706. Public Library of Science 10.1371/journal.pone.0239706

Lemmin, Thomas; Kalbermatter, David; Harder, Daniel; Plattet, Philippe; Fotiadis, Dimitrios (2020). Structures and dynamics of the novel S1/S2 protease cleavage site loop of the SARS-CoV-2 spike glycoprotein. Journal of structural biology: X, 4, p. 100038. Elsevier 10.1016/j.yjsbx.2020.100038

2019

Kappel, Sven; Borgström, Anna; Stoklosa, Paulina; Dörr, Kathrin; Peinelt, Christine (2019). Store-operated calcium entry in disease: Beyond STIM/Orai expression levels. Seminars in cell & developmental biology, 94, pp. 66-73. Elsevier 10.1016/j.semcdb.2019.01.003

R. Cunha, Micael; Bhardwaj, Rajesh; Lindinger, Sonja; Butorac, Carmen; Romanin, Christoph; Hediger, Matthias; Reymond, Jean-Louis (2019). Photoswitchable Inhibitor of the Calcium Channel TRPV6. ACS medicinal chemistry letters, 10(9), pp. 1341-1345. American Chemical Society 10.1021/acsmedchemlett.9b00298

Pereira, Gustavo José Vasco; Tavares, Maurício Temotheo; Azevedo, Ricardo Alexandre; Martins, Barbara Behr; Rodrigues Cunha, Micael; Bhardwaj, Rajesh; Cury, Yara; Zambelli, Vanessa Olzon; Barbosa, Euzébio Guimarães; Hediger, Matthias A.; Parise-Filho, Roberto (2019). Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling. Bioorganic & medicinal chemistry, 27(13), pp. 2893-2904. Elsevier 10.1016/j.bmc.2019.05.020

El Mokh, Oussama; Taelmann, Vincent; Radojewski, Piotr; Rölli, Matthias Andreas; Stooss, Amandine; Dumont, Rebecca A; Dettmer, Matthias; Phillips, Wayne; Walter, Martin Alexander; Charles, Roch-Philippe (2019). MEK inhibition induces therapeutic iodine uptake in a murine model of anaplastic thyroid cancer. Journal of nuclear medicine, 60(7), pp. 917-923. Society of Nuclear Medicine 10.2967/jnumed.118.216721

Fotiadis, Dimitrios; Jeckelmann, Jean-Marc (2019). The structure of the human 4F2hc-LAT1 heteromeric amino acid transporter. Science China. Life sciences, 62(6), pp. 848-850. Springer 10.1007/s11427-019-9558-5

Häfliger, Pascal; Charles, Roch-Philippe (2019). The L-Type Amino Acid Transporter LAT1-An Emerging Target in Cancer. International journal of molecular sciences, 20(10) MDPI 10.3390/ijms20102428

Gertsch, Jürg (2019). Scaffold and organism hopping with chemical probes. Nature chemical biology, 15(5), pp. 428-429. Springer Nature 10.1038/s41589-019-0275-9

Melhem, Hassan; Kallol, Sampada; Huang, Xiao; Lüthi, Michael; Ontsouka, Edgar; Keogh, Adrian; Stroka, Deborah; Thormann, Wolfgang; Schneider, Henning; Albrecht, Christiane (2019). Placental secretion of apolipoprotein A1 and E: the anti-atherogenic impact of the placenta. Scientific Reports, 9(1), p. 6225. Nature Publishing Group 10.1038/s41598-019-42522-1

Stergachis, Andrew B; Pujol Gimenez, Jonai; Gyimesi, Gergely; Fuster, Daniel Guido; Albano, Giuseppe; Troxler, Marina; Picker, Jonathan; Rosenberg, Paul A; Bergin, Ann; Peters, Jurriaan; Moufawad El Achkar, Christelle; Harini, Chellamani; Manzi, Shannon; Rotenberg, Alexander; Hediger, Matthias A.; Rodan, Lance H (2019). Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism. Annals of neurology, 85(6), pp. 921-926. Wiley-Blackwell 10.1002/ana.25477

Gyimesi, Gergely; Albano, Giuseppe; Fuster, Daniel Guido; Hediger, Matthias A; Pujol Gimenez, Jonai (2019). Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2). Journal of biological chemistry, 294(20), pp. 8046-8063. American Society for Biochemistry and Molecular Biology 10.1074/jbc.RA118.006113

Delalande, Clémence; Awale, Mahendra; Rubin, Matthias; Probst, Daniel; Ozhathil, Lijo C.; Gertsch, Jürg; Abriel, Hugues; Reymond, Jean-Louis (2019). Optimizing TRPM4 inhibitors in the MHFP6 chemical space. European journal of medicinal chemistry, 166, pp. 167-177. Elsevier 10.1016/j.ejmech.2019.01.048

Granchi, Carlotta; Lapillo, Margherita; Glasmacher, Sandra; Bononi, Giulia; Licari, Cristina; Poli, Giulio; El Boustani, Maguie; Caligiuri, Isabella; Rizzolio, Flavio; Gertsch, Jürg; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano; Chicca, Andrea (2019). Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor. Journal of medicinal chemistry, 62(4), pp. 1932-1958. American Chemical Society 10.1021/acs.jmedchem.8b01483

Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2019). Volta Phase Plate Cryo-EM Structure of the Human Heterodimeric Amino Acid Transporter 4F2hc-LAT2. International journal of molecular sciences, 20(4) MDPI 10.3390/ijms20040931

Kalbermatter, David; Shrestha, Neeta; Ebert, Nadine; Herren, Michael; Moll, Pascal Dominique; Plemper, Richard K; Altmann, Karl-Heinz; Langedijk, Johannes P; Gall, Flavio; Lindenmann, Urs; Riedl, Rainer; Fotiadis, Dimitrios José; Plattet, Philippe (2019). Primary resistance mechanism of the canine distemper virus fusion protein against a small-molecule membrane fusion inhibitor. Virus research, 259, pp. 28-37. Elsevier 10.1016/j.virusres.2018.10.003

Lüscher, Benjamin; Surbek, Daniel; Clemençon, Benjamin; Huang, Xiao; Albrecht, Christiane; Marini, Camilla; Hediger, Matthias; Baumann, Marc (2019). Different Pharmacological Properties of GLUT9a and GLUT9b: Potential Implications in Preeclampsia. Cellular physiology and biochemistry, 53(3), pp. 508-517. Cell Physiol Biochem Press 10.33594/000000154

Bosshart, Patrick; Fotiadis, Dimitrios (2019). Secondary Active Transporters. Sub-cellular biochemistry, 92, pp. 275-299. Springer 10.1007/978-3-030-18768-2_9

Bosshart, Patrick; Kalbermatter, David; Bonetti, Sara; Fotiadis, Dimitrios (2019). Structure and function of a monocarboxylate transporter homolog specific for L-lactate. Molecular & cellular oncology, 6(6), e1646605. Taylor & Francis 10.1080/23723556.2019.1646605

Zaugg, Jonas; Ziegler, Fabian; Nuoffer, Jean-Marc; Moser-Hässig, Ruedi; Albrecht, Christiane (2019). EFFICIENT LEUCINE TRANSPORT ACROSS THE PLACENTAL BARRIER DEPENDS ON PHYSIOLOGICAL, OPPOSITELY DIRECTED LEUCINE GRADIENTS. Placenta, 83, e113-e113. Elsevier

Kallol, Sampada; Briggs, Louise; Mistry, Hiten D.; Moser, Ruedi; Schneider, Henning; Albrecht, Christiane (2019). COMPARISON OF IN VITRO PRE-ECLAMPSIA (PE) CELL MODELS WITH PE PLACENTAL TISSUE. Placenta, 83, e104-e104. Elsevier

Zaugg, Jonas; Zurkinden, Line; Melhem, Hassan; Kalakaran, Thuvaraga; Albrecht, Christiane (2019). ANTIOXIDANT TREATMENT RESCUES THE HYPERGLYCEMIC AND HYPERLIPIDEMIC EFFECTS ON PLACENTAL IRON HOMEOSTASIS. Placenta, 83, e93-e93. Elsevier

2018

Kallol, Sampada Arvindrao; Moser-Haessig, Ruedi; Ontsouka, Edgar; Albrecht, Christiane (2018). Comparative expression patterns of selected membrane transporters in differentiated BeWo and human primary trophoblast cells. Placenta, 72-73, pp. 48-52. Elsevier 10.1016/j.placenta.2018.10.008

Kandasamy, Palanivel; Gyimesi, Gergely; Kanai, Yoshikatsu; Hediger, Matthias (2018). Amino acid transporters revisited: New views in health and disease. Trends in biochemical sciences, 43(10), pp. 752-789. Elsevier Current Trends 10.1016/j.tibs.2018.05.003

Chicca, Andrea; Schafroth, M A; Reynoso, Ines del Carmen; Erni, R; Petrucci, Vanessa; Carreira, E M; Gertsch, Jürg (2018). Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high. Science Advances, 4(10), eaat2166. American Association for the Advancement of Science 10.1126/sciadv.aat2166

Häfliger, Pascal; Graff, Julien; Rubin, Matthias; Stooss, Amandine; Dettmer, Matthias S.; Altmann, Karl-Heinz; Gertsch, Jürg; Charles, Roch-Philippe (2018). The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model. Journal of experimental & clinical cancer research, 37(1), p. 234. BioMed Central 10.1186/s13046-018-0907-z

Bononi, Giulia; Granchi, Carlotta; Lapillo, Margherita; Giannotti, Massimiliano; Nieri, Daniela; Fortunato, Serena; Boustani, Maguie El; Caligiuri, Isabella; Poli, Giulio; Carlson, Kathryn E; Kim, Sung Hoon; Macchia, Marco; Martinelli, Adriano; Rizzolio, Flavio; Chicca, Andrea; Katzenellenbogen, John A; Minutolo, Filippo; Tuccinardi, Tiziano (2018). Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors. European journal of medicinal chemistry, 157, pp. 817-836. Elsevier Masson SAS 10.1016/j.ejmech.2018.08.038

Chien, Huan-Chieh; Colas, Claire; Finke, Karissa; Springer, Seth; Stoner, Laura; Zur, Arik A; Venteicher, Brooklynn; Campbell, Jerome; Hall, Colton; Flint, Andrew; Augustyn, Evan; Hernandez, Christopher; Heeren, Nathan; Hansen, Logan; Anthony, Abby; Bauer, Justine; Fotiadis, Dimitrios José; Schlessinger, Avner; Giacomini, Kathleen M and Thomas, Allen A (2018). Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1). Journal of medicinal chemistry, 61(16), pp. 7358-7373. American Chemical Society 10.1021/acs.jmedchem.8b01007

Kallol, Sampada Arvindrao; Huang, Xiao; Müller, Stefan Jürg; Ontsouka, Edgar; Albrecht, Christiane (2018). Novel Insights into Concepts and Directionality of Maternal⁻Fetal Cholesterol Transfer across the Human Placenta. International journal of molecular sciences, 19(8) MDPI 10.3390/ijms19082334

Zákány, Nóra; Oláh, Attila; Markovics, Arnold; Takács, Erika; Aranyász, Andrea; Nicolussi, Simon; Piscitelli, Fabiana; Allarà, Marco; Pór, Ágnes; Kovács, Ilona; Zouboulis, Christos C; Gertsch, Jürg; Di Marzo, Vincenzo; Bíró, Tamás; Szabó, Tamás (2018). Endocannabinoid Tone Regulates Human Sebocyte Biology. Journal of Investigative Dermatology, 138(8), pp. 1699-1706. Nature Publishing 10.1016/j.jid.2018.02.022

Bianchi, Beatrice; Smith, Paul A; Abriel, Hugues (2018). The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration. Molecular brain, 11(1), p. 41. BioMed Central 10.1186/s13041-018-0385-4

Franz, Marie-Christine; Pujol Gimenez, Jonai; Montalbetti, Nicolas; Fernandez Tenorio, Miguel; DeGrado, Timothy R.; Niggli, Ernst; Romero, Michael F.; Hediger, Matthias (2018). Reassessment of the transport mechanism of the human zinc transporter SLC39A2. Biochemistry, 57(26), pp. 3976-3986. American Chemical Society 10.1021/acs.biochem.8b00511

Fuster, Daniel G.; Moe, Orson W (2018). Incomplete Distal Renal Tubular Acidosis and Kidney Stones. Advances in chronic kidney disease, 25(4), pp. 366-374. Elsevier 10.1053/j.ackd.2018.05.007

Chicca, Andrea; Arena, Chiara; Bertini, Simone; Gado, Francesca; Ciaglia, Elena; Abate, Mario; Digiacomo, Maria; Lapillo, Margherita; Poli, Giulio; Bifulco, Maurizio; Macchia, Marco; Tuccinardi, Tiziano; Gertsch, Jürg; Manera, Clementina (2018). Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system. European journal of medicinal chemistry, 154, pp. 155-171. Elsevier 10.1016/j.ejmech.2018.05.019

Ozhathil, Lijo Cherian; Delalande, Clémence Marie Sandrine; Bianchi, Beatrice; Nemeth, Gabor; Kappel, Sven; Thomet, Urs; Ross, Daniela; Simonin, Céline; Rubin, Matthias; Gertsch, Jürg; Lochner, Martin; Peinelt, Christine; Reymond, Jean-Louis; Abriel, Hugues (2018). Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. British journal of pharmacology, 175(12), pp. 2504-2519. Wiley-Blackwell 10.1111/bph.14220

Schroeder, Mariana; Jakovcevski, Mira; Polacheck, Tamar; Drori, Yonat; Luoni, Alessia; Röh, Simone; Zaugg, Jonas; Ben-Dor, Shifra; Albrecht, Christiane; Chen, Alon (2018). Placental miR-340 mediates vulnerability to activity based anorexia in mice. Nature communications, 9(1), p. 1596. Nature Publishing Group 10.1038/s41467-018-03836-2

Clemençon, Benjamin; Lüscher, Benjamin; Hediger, Matthias (2018). Establishment of a novel microscale thermophoresis ligand-binding assay for characterization of SLC solute carriers using oligopeptide transporter PepT1 (SLC15 family) as a model system. Journal of pharmacological and toxicological methods, 92, pp. 67-76. Elsevier 10.1016/j.vascn.2018.03.004

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Colas, Claire; Ucurum Fotiadis, Zöhre; Schlessinger, Avner; Fotiadis, Dimitrios José (2018). Effects of Mutations and Ligands on the Thermostability of the l-Arginine/Agmatine Antiporter AdiC and Deduced Insights into Ligand-Binding of Human l-Type Amino Acid Transporters. International journal of molecular sciences, 19(3) MDPI 10.3390/ijms19030918

Huang, Xiao; Anderle, Pascale; Hostettler, Lu; Baumann, Marc; Surbek, Daniel; Ontsouka, Edgar; Albrecht, Christiane (2018). Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia. BMC Genomics, 19(1), p. 173. BioMed Central 10.1186/s12864-018-4518-z

Aghazadeh Tabrizi, Mojgan; Baraldi, Pier Giovanni; Baraldi, Stefania; Ruggiero, Emanuela; De Stefano, Lucia; Rizzolio, Flavio; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Chicca, Andrea; Lapillo, Margherita; Gertsch, Jürg; Manera, Clementina; Macchia, Marco; Martinelli, Adriano; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano (2018). Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors. Journal of medicinal chemistry, 61(3), pp. 1340-1354. American Chemical Society 10.1021/acs.jmedchem.7b01845

Varga, Zoltan V; Matyas, Csaba; Erdelyi, Katalin; Cinar, Resat; Nieri, Daniela; Chicca, Andrea; Nemeth, Balazs Tamas; Paloczi, Janos; Lajtos, Tamas; Corey, Lukas; Hasko, Gyorgy; Gao, Bin; Kunos, George; Gertsch, Jürg; Pacher, Pal (2018). Beta-caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice. British journal of pharmacology, 175(2), pp. 320-334. Wiley-Blackwell 10.1111/bph.13722

Bianchi, Beatrice; Ozhathil, Lijo Cherian; Medeiros Domingo, Argelia; Gollob, Michael H; Abriel, Hugues (2018). Four TRPM4 Cation Channel Mutations Found in Cardiac Conduction Diseases Lead to Altered Protein Stability. Frontiers in physiology, 9, p. 177. Frontiers Research Foundation 10.3389/fphys.2018.00177

Reynoso, Ines del Carmen; Chicca, Andrea; Flores-Soto, Mario E; Viveros-Paredes, Juan M; Gertsch, Jürg (2018). The Endocannabinoid Reuptake Inhibitor WOBE437 Is Orally Bioavailable and Exerts Indirect Polypharmacological Effects via Different Endocannabinoid Receptors. Frontiers in molecular neuroscience, 11, p. 180. Frontiers Research Foundation 10.3389/fnmol.2018.00180

2017

Bertini, Simone; Chicca, Andrea; Gado, Francesca; Arena, Chiara; Nieri, Daniela; Digiacomo, Maria; Saccomanni, Giuseppe; Zhao, Pingwei; Abood, Mary E; Macchia, Marco; Gertsch, Jürg; Manera, Clementina (2017). Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor. Bioorganic & medicinal chemistry, 25(24), pp. 6427-6434. Elsevier 10.1016/j.bmc.2017.10.015

Rölli, Matthias Andreas; Ruffieux-Daidiée, Dorothée; Stooss, Amandine; El Mokh, Oussama; Phillips, Wayne A; Dettmer, Matthias; Charles, Roch-Philippe (2017). PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors. OncoTarget, 8(61), pp. 103207-103222. Impact Journals LLC 10.18632/oncotarget.21732

Chicca, Andrea; Berg, Regina; Jessen, Henning J; Marck, Nicolas; Schmid, Fabian; Burch, Patrick; Gertsch, Jürg; Gademann, Karl (2017). Biological evaluation of pyridone alkaloids on the endocannabinoid system. Bioorganic & medicinal chemistry, 25(22), pp. 6102-6114. Elsevier 10.1016/j.bmc.2017.02.031

Kappel, Sven; dos Santos Marques, Ines Joao; Zoni, Eugenio; Stoklosa, Paulina Agnieszka; Peinelt, Christine; Mercader Huber, Nadia; Kruithof-de Julio, Marianna; Borgström, Anna (2017). Store-Operated Ca2+ Entry as a Prostate Cancer Biomarker — a Riddle with Perspectives. Current Molecular Biology Reports, 3(4), pp. 208-217. Springer 10.1007/s40610-017-0072-8

Chicca, Andrea; Nicolussi, Simon; Bartholomäus, Ruben; Blunder, Martina; Aparisi Rey, Alejandro; Petrucci, Vanessa; Reynoso, Ines del Carmen; Viveros-Paredes, Juan Manuel; Dalghi Gens, Marianela Gisela; Lutz, Beat; Schiöth, Helgi B; Soeberdt, Michael; Abels, Christoph; Charles, Roch-Philippe; Altmann, Karl-Heinz; Gertsch, Jürg (2017). Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(25), E5006-E5015. National Academy of Sciences NAS 10.1073/pnas.1704065114

Gertsch, Jürg (2017). Cannabimimetic phytochemicals in the diet - an evolutionary link to food selection and metabolic stress adaptation? British journal of pharmacology, 174(11), pp. 1464-1483. Wiley-Blackwell 10.1111/bph.13676

Hinard, Valérie; Britan, Aurore; Schaeffer, Mathieu; Zahn-Zabal, Monique; Thomet, Urs; Rougier, Jean-Sébastien; Bairoch, Amos; Abriel, Hugues; Gaudet, Pascale (2017). Annotation of functional impact of voltage-gated sodium channel mutations. Human mutation, 38(5), pp. 485-493. Wiley-Blackwell 10.1002/humu.23191

El Mokh, Oussama; Ruffieux-Daidié, Dorothée; Rölli, Matthias Andreas; Stooss, Amandine; Phillips, Wayne A; Gertsch, Jürg; Dettmer, Matthias; Charles, Roch-Philippe (2017). Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo. OncoTarget, 8(15), pp. 24604-24620. Impact Journals LLC 10.18632/oncotarget.15599

Gachet Otanez, Maria Salomé; Schubert, Alexandra; Calarco, Serafina; Boccard, Julien; Gertsch, Jürg (2017). Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom. Scientific Reports, 7, p. 41177. Nature Publishing Group 10.1038/srep41177

Ontsouka, Edgar; Huang, Xiao; Aliyev, Eldar; Albrecht, Christiane (2017). In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland. Molecular and cellular endocrinology, 439, pp. 35-45. Elsevier Ireland 10.1016/j.mce.2016.10.016

Albano, Giuseppe; Dolder, Silvia; Siegrist, Mark; Mercier-Zuber, Annie; Auberson, Muriel; Stoudmann, Candice; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2017). Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1). Pflügers Archiv : European journal of physiology, 469(2), pp. 225-233. Springer 10.1007/s00424-016-1923-5

Martínez-Pacheco, Heidy; Ramírez-Galicia, Guillermo; Vergara-Arias, Midalia; Gertsch, Jürg; Fragoso-Vázquez, Jonathan Manuel; Méndez-Luna, David; Abujamra, A L; Cristina, Cabrera-Pérez Laura; Cecilia, Rosales-Hernández Martha; Mendoza-Lujambio, I; Correa-Basurto, José (2017). Docking and QSAR studies of aryl-valproic acid derivatives to identify anti-proliferative agents targeting the HDAC8. Anti-cancer agents in medicinal chemistry, 17(7), pp. 927-940. Bentham Science Publishers

2016

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Gapsys, Vytautas; Ucurum Fotiadis, Zöhre; de Groot, Bert L; Fotiadis, Dimitrios José (2016). Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(37), pp. 10358-10363. National Academy of Sciences NAS 10.1073/pnas.1605442113

Xie, Wenjie; Dolder, Silvia; Siegrist, Mark; Wetterwald, Antoinette; Hofstetter, Wilhelm (2016). Glutamate Receptor Agonists and Glutamate Transporter Antagonists Regulate Differentiation of Osteoblast Lineage Cells. Calcified tissue international, 99(2), pp. 142-154. Springer 10.1007/s00223-016-0129-3

Gambaro, Giovanni; Croppi, Emanuele; Coe, Fredric; Lingeman, James; Moe, Orson; Worcester, Elen; Buchholz, Noor; Bushinsky, David; Curhan, Gary C; Ferraro, Pietro Manuel; Fuster, Daniel Guido; Goldfarb, David S; Heilberg, Ita Pfeferman; Hess, Bernard; Lieske, John; Marangella, Martino; Milliner, Dawn; Preminger, Glen M; Reis Santos, Jose' Manuel; Sakhaee, Khashayar; ... (2016). Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement. Journal of nephrology JN, 29(6), pp. 715-734. Springer 10.1007/s40620-016-0329-y

Bertini, Simone; Chicca, Andrea; Arena, Chiara; Chicca, Stefano; Saccomanni, Giuseppe; Gertsch, Jürg; Manera, Clementina; Macchia, Marco (2016). Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands. European journal of medicinal chemistry, 116, pp. 252-266. Elsevier Masson SAS 10.1016/j.ejmech.2016.03.072

Syam, Ninda Ratna Maharani; Chatel, Stéphanie; Ozhathil, Lijo Cherian; Sottas, Valentin; Rougier, Jean-Sébastien; Baruteau, Alban; Baron, Estelle; Amarouch, Mohamed Yassine; Daumy, Xavier; Probst, Vincent; Schott, Jean-Jacques; Abriel, Hugues (2016). Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block. Journal of the American Heart Association, 5(5) American Heart Association 10.1161/JAHA.114.001625

Gertsch, Jürg (2016). Editorial: Lung macrophages high on cannabinoids: jamming PAMs and taming TAMs? Journal of leukocyte biology, 99(4), pp. 518-520. Society for Leukocyte Biology 10.1189/jlb.3CE0915-409RR

Daumy, Xavier; Amarouch, Mohamed Yassine; Lindenbaum, Pierre; Bonnaud, Stéphanie; Charpentier, Eric; Bianchi, Beatrice; Nafzger, Sabine Naomi; Baron, Estelle; Fouchard, Swanny; Thollet, Aurélie; Kyndt, Florence; Barc, Julien; Le Scouarnec, Solena; Makita, Naomasa; Le Marec, Hervé; Dina, Christian; Gourraud, Jean-Baptiste; Probst, Vincent; Abriel, Hugues; Redon, Richard; ... (2016). Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I. International journal of cardiology, 207, pp. 349-358. Elsevier 10.1016/j.ijcard.2016.01.052

Albrecht, Christiane; Caniggia, I; Clifton, V; Göhner, C; Harris, L; Hemmings, D; Jawerbaum, A; Johnstone, E; Jones, H; Keelan, J; Lewis, R; Mitchell, M; Murthi, P; Powell, T; Saffery, R; Smith, R; Vaillancourt, C; Wadsack, C; Salomon, C (2016). IFPA meeting 2015 workshop report IV: Nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid mediators and placental function. Placenta, 48 Suppl 1, S12-S16. Elsevier 10.1016/j.placenta.2016.01.003

Awale, Mahendra; Reymond, Jean-Louis (2016). Web-based 3D-visualization of the DrugBank chemical space. Journal of cheminformatics, 8, p. 25. Springer 10.1186/s13321-016-0138-2

Rau, Mark; Nicolussi, Simon; Chicca, Andrea; Gertsch, Jürg (2016). Assay of Endocannabinoid Uptake. In: Maccarrone, Mauro (ed.) Endocannabinoid Signaling. Methods and Protocols. Methods in Molecular Biology: Vol. 1412 (pp. 191-203). New York: Springer 10.1007/978-1-4939-3539-0_20

Boggavarapu, Venkata Ravi Naga Rajendr; Hirschi, Stephan; Harder, Daniel; Meury, Marcel; Ucurum Fotiadis, Zöhre; Bergeron, Marc; Fotiadis, Dimitrios José (2016). Purification of Human and Mammalian Membrane Proteins Expressed in Xenopus laevis Frog Oocytes for Structural Studies. In: Mus-Veteau, Isabelle (ed.) Heterologous Expression of Membrane Proteins. Methods and Protocols. Methods in Molecular Biology: Vol. 1432 (pp. 223-242). New York: Springer 10.1007/978-1-4939-3637-3_14

2015

Del Carlo, S; Manera, C; Chicca, Andrea; Arena, C; Bertini, S; Burgalassi, S; Tampucci, S; Gertsch, Jürg; Macchia, M; Saccomanni, G (2015). Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase. Journal of pharmaceutical and biomedical analysis, 108, pp. 113-121. Pergamon Press 10.1016/j.jpba.2015.02.007

Awale, Mahendra; Reymond, Jean-Louis (2015). Similarity Mapplet: Interactive Visualization of the Directory of Useful Decoys and ChEMBL in High Dimensional Chemical Spaces. Journal of chemical information and modeling, 55(8), pp. 1509-1516. American Chemical Society 10.1021/acs.jcim.5b00182

2014

Chicca, Andrea; Caprioglio, Diego; Minassi, Alberto; Petrucci, Vanessa; Appendino, Giovanni; Taglialatela-Scafati, Orazio; Gertsch, Jürg (2014). Functionalization of β-caryophyllene generates novel polypharmacology in the endocannabinoid system. ACS Chemical Biology, 9(7), pp. 1499-1507. American Chemical Society 10.1021/cb500177c

2013

Charles, Roch-Philippe; Silva, Jilian; Iezza, Gioia; Phillips, Wayne A; McMahon, Martin (2013). BRAF V600E and PIK3CA H1074R cooperate to promote progression of anaplastic thyroid carcinoma in the mouse. Endocrine abstracts, 32(S16.1) BioScientifica 10.1530/endoabs.32.s16.1

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