 | Up a level |
Traidl-Hoffmann, Claudia; Afghani, Jamie; Akdis, Cezmi; Akdis, Mübecel; Aydin, Handan; Bärenfaller, Katja; Behrendt, Heidrun; Bieber, Thomas; Bigliardi, Paul; Bigliardi-Qi, Mei; Bonefeld, Charlotte Menné; Bösch, Stefanie; Brüggen, Marie Charlotte; Diemert, Sebastian; Duchna, Hans-Werner; Fähndrich, Martina; Fehr, Danielle; Fellmann, Marc; Frei, Remo; Garvey, Lena H; ... (2024). Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration. Allergy, 79(10), pp. 2605-2624. Wiley 10.1111/all.16247
Kapp, Friedrich G; Bazgir, Farhad; Mahammadzade, Nagi; Mehrabipour, Mehrnaz; Vassella, Erik; Bernhard, Sarah M; Döring, Yvonne; Holm, Annegret; Karow, Axel; Seebauer, Caroline; Platz Batista da Silva, Natascha; Wohlgemuth, Walter A; Oppenheimer, Aviv; Kröning, Pia; Niemeyer, Charlotte M; Schanze, Denny; Zenker, Martin; Eng, Whitney; Ahmadian, Mohammad R; Baumgartner, Iris; ... (2024). Somatic RIT1 delins in arteriovenous malformations hyperactivate RAS-MAPK signaling amenable to MEK inhibition. (In Press). Angiogenesis Springer 10.1007/s10456-024-09934-8
Moriconi, Stefano; Rodríguez-Núñez, Omar; Gros, Romane; Felger, Leonard A; Maragkou, Theoni; Hewer, Ekkehard; Pierangelo, Angelo; Novikova, Tatiana; Schucht, Philippe; McKinley, Richard (2024). Near-real-time Mueller polarimetric image processing for neurosurgical intervention. International journal of computer assisted radiology and surgery, 19(6), pp. 1033-1043. Springer 10.1007/s11548-024-03090-6
Gros, Romane; Rodríguez-Núñez, Omar; Felger, Leonard; Moriconi, Stefano; McKinley, Richard; Pierangelo, Angelo; Novikova, Tatiana; Vassella, Erik; Schucht, Philippe; Hewer, Ekkehard; Maragkou, Theoni (2024). Characterization of Polarimetric Properties in Various Brain Tumor Types Using Wide-Field Imaging Mueller Polarimetry. IEEE Transactions on Medical Imaging, p. 1. 10.1109/TMI.2024.3413288
Bernhard, Sarah M.; Tuleja, Aleksandra Beata; Döring, Yvonne; Vassella, Erik; Amstutz, Ursula; Zweier, Christiane; Rössler, Jochen; Boon, Laurence M.; Vikkula, Miikka; Haupt, Fabian; Hamvas, Györgyi; Kammer, Rafael; Baumgartner, Iris (9 May 2024). Oncogene targeted next-generation-sequencing in extracranial arteriovenous malformations (Unpublished). In: Word ISSVA Congress 2024. Madrid, Spain. 7-10 May, 2024.
Rafiq, Sreoshee; Mungure, Irene; Banz, Yara; Niklaus, Nicolas J.; Kaufmann, Thomas; Müller, Stefan; Jacquel, Arnaud; Robert, Guillaume; Auberger, Patrick; Torbett, Bruce E; Muller, Sylviane; Tschan, Mario P.; Humbert, Magali (2024). HSPA8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation. Pharmacology, 109(4), pp. 216-230. Karger 10.1159/000537864
Mandhair, Harpreet K; Radpour, Ramin; Westerhuis, Mira; Banz, Yara; Humbert, Magali; Arambasic, Miroslav; Dengjel, Jörn; Davies, Andrew; Tschan, Mario P; Novak, Urban (2024). Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach. Leukemia, 38(2), pp. 424-429. Nature Publishing Group 10.1038/s41375-024-02147-4
Themis-Areti A, Andreoti; Tuleja, Aleksandra; Döring, Yvonne; Maiolo, Massimo; Schaller, André; Vassella, Erik; Zweier, Christiane; Boon, Laurence M; Vikkula, Miikka; Rössler, Jochen; Bernhard, Sarah M.; Baumgartner, Iris (2023). Parkes Weber Syndrome: Contribution of the Genotype to the Diagnosis. Journal of vascular anomalies, 4(4), e076. Wolters Kluwer Health 10.1097/JOVA.0000000000000076
Seiler, Kristina; Rafiq, Sreoshee; Tschan, Mario P (2023). Isoform-specific, Semi-quantitative Determination of Highly Homologous Protein Levels via CRISPR-Cas9-mediated HiBiT Tagging. Bio-protocol, 13(14), e4777. bio-protocol 10.21769/BioProtoc.4777
Carone, Marianna; Spalinger, Marianne R; Gaultney, Robert A; Mezzenga, Raffaele; Hlavacková, Kristyna; Mookhoek, Aart; Krebs, Philippe; Rogler, Gerhard; Luciani, Paola; Aleandri, Simone (2023). Temperature-triggered in situ forming lipid mesophase gel for local treatment of ulcerative colitis. Nature Communications, 14(1), p. 3489. Springer Nature 10.1038/s41467-023-39013-3
Barrera, Cristian; Corredor, Germán; Viswanathan, Vidya Sankar; Ding, Ruiwen; Toro, Paula; Fu, Pingfu; Buzzy, Christina; Lu, Cheng; Velu, Priya; Zens, Philipp; Berezowska, Sabina; Belete, Merzu; Balli, David; Chang, Han; Baxi, Vipul; Syrigos, Konstantinos; Rimm, David L; Velcheti, Vamsidhar; Schalper, Kurt; Romero, Eduardo; ... (2023). Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer. NPJ precision oncology, 7(1), p. 52. Springer Nature 10.1038/s41698-023-00403-x
Maragkou, Theoni; Reinhard, Stefan; Jungo, Patric; Pasquier, Baptiste; Neuenschwander, Maja; Schucht, Philippe; Vassella, Erik; Hewer, Ekkehard Walter (2023). Evaluation of MTAP and p16 immunohistochemical deficiency as surrogate marker for CDKN2A/B homozygous deletion in gliomas. Pathology, 55(4), pp. 466-477. Elsevier 10.1016/j.pathol.2023.01.005
Kashani, Elham; Schnidrig, Désirée; Hashemi Gheinani, Ali; Ninck, Martina Selina; Zens, Philipp; Maragkou, Theoni; Baumgartner, Ulrich; Schucht, Philippe; Rätsch, Gunnar; Rubin, Mark A; Berezowska, Sabina; Ng, Charlotte K Y; Vassella, Erik (2023). Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors. Neuro-Oncology, 25(4), pp. 662-673. Oxford University Press 10.1093/neuonc/noac220
Gros, Romain; Rodríguez-Núñez, Omar; Felger, Leonard; Moriconi, Stefano; McKinley, Richard; Pierangelo, Angelo; Novikova, Tatiana; Vassella, Erik; Schucht, Philippe; Hewer, Ekkehard; Maragkou, Theoni (2023). Effects of formalin fixation on polarimetric properties of brain tissue: fresh or fixed? Neurophotonics, 10(2), 025009. SPIE 10.1117/1.NPh.10.2.025009
Wallimann, Alexandra; Schenk, Mirjam (2023). IL-32 as a potential biomarker and therapeutic target in skin inflammation. Frontiers in immunology, 14(1264236), p. 1264236. Frontiers Research Foundation 10.3389/fimmu.2023.1264236
Eliçin, Olgun; Monney, Bastien; Dettmer, Matthias; Caparrotti, F; Centeno Ramos, Irene; Nisa Hernandez, Lluis; Limacher, Andreas; Vassella, Erik; Giger, Roland (2023). Transcriptomic response of oral squamous cell carcinoma to metformin treatment - a prospective study (Unpublished). In: ECHNO 10th annual congress. Lisbon. 08 – 11 March.
Kapp, Friedrich G.; Bazgir, Farhad; Mahammadzade, Nagi; Vassella, Erik; Döring, Yvonne; Karow, Axel; Seebauer, Caroline; Platz Batista da Silva, Natascha; Wohlgemuth, Walter A.; Krönig, Pia; Niemeyer, Charlotte M.; Schanze, Denny; Zenker, Martin; Eng, Whitney; Ahmadian, Mohammad R.; Baumgartner, Iris; Rössler, Jochen (2023). Somatic RIT1 indels identified in arteriovenous malformations hyperactivate RAS-MAPK signaling and are amenable to MEK inhibition (medRxiv). Cold Spring Harbor Laboratory 10.1101/2023.11.13.23298448
Zens, Philipp; Bello, Corina Manuela; Scherz, Amina; von Gunten, Michael; Ochsenbein, Adrian; Schmid, Ralph A; Berezowska, Sabina (2022). The effect of neoadjuvant therapy on PD-L1 expression and CD8+lymphocyte density in non-small cell lung cancer. Modern pathology, 35(12), pp. 1848-1859. Springer Nature 10.1038/s41379-022-01139-y
Kündig, Alexandra; Zens, Philipp; Fung, Christian; Scherz, Amina; Cerciello, Ferdinando; Herrmann, Evelyn; Ermis, Ekin; Schmid, Ralph A; Vassella, Erik; Berezowska, Sabina (2022). Programmed Death-Ligand 1 Expression in Lung Cancer and Paired Brain Metastases-a Single-Center Study in 190 Patients. JTO clinical and research reports, 3(11), p. 100413. 10.1016/j.jtocrr.2022.100413
Kashani, Elham; Vassella, Erik (2022). Pleiotropy of PP2A Phosphatases in Cancer with a Focus on Glioblastoma IDH Wildtype. Cancers, 14(21) MDPI AG 10.3390/cancers14215227
Pied, Noémie; Daussy, Coralie F; Denis, Zoé; Ragues, Jessica; Faure, Muriel; Iggo, Richard; Tschan, Mario P; Roger, Benoit; Rayne, Fabienne; Wodrich, Harald (2022). TBK1 is part of a galectin 8 dependent membrane damage recognition complex and drives autophagy upon Adenovirus endosomal escape. PLoS pathogens, 18(7), e1010736. Public Library of Science 10.1371/journal.ppat.1010736
Häni, Levin; Kopcic, Monika; Branca, Mattia; Schütz, Alessa; Murek, Michael; Söll, Nicole; Vassella, Erik; Raabe, Andreas; Hewer, Ekkehard; Schucht, Philippe (2022). Quantitative Analysis of the MGMT Methylation Status of Glioblastomas in Light of the 2021 WHO Classification. Cancers, 14(13), p. 3149. MDPI AG 10.3390/cancers14133149
Ding, Ruiwen; Prasanna, Prateek; Corredor, Germán; Barrera, Cristian; Zens, Philipp; Lu, Cheng; Velu, Priya; Leo, Patrick; Beig, Niha; Li, Haojia; Toro, Paula; Berezowska, Sabina; Baxi, Vipul; Balli, David; Belete, Merzu; Rimm, David L; Velcheti, Vamsidhar; Schalper, Kurt; Madabhushi, Anant (2022). Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome. NPJ precision oncology, 6(1), p. 33. Springer Nature 10.1038/s41698-022-00277-5
Kremenovic, Mirela; Chan, Alfred A; Feng, Bing; Bäriswyl, Lukas; Robatel, Steve; Gruber, Thomas; Tang, Li; Lee, Delphine J; Schenk, Mirjam (2022). BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma. Journal for immunotherapy of cancer, 10(6), e004133. BioMed Central 10.1136/jitc-2021-004133
Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w
Robatel, Steve; Schenk, Mirjam (2022). Current Limitations and Novel Perspectives in Pancreatic Cancer Treatment. Cancers, 14(4) MDPI AG 10.3390/cancers14040985
Gianni’, Maurizio; Goracci, Laura; Schlaefli, Anna; Di Veroli, Alessandra; Kurosaki, Mami; Guarrera, Luca; Bolis, Marco; Foglia, Marika; Lupi, Monica; Tschan, Mario; Cruciani, Gabriele; Terao, Mineko; Garattini, Enrico (2022). Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia. Cell death & disease, 13(1), p. 30. Nature Publishing Group 10.1038/s41419-021-04476-z
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Vassella, Erik; Kashani, Elham; Zens, Philipp; Kündig, Alexandra; Fung, Christian; Scherz, Amina; Herrmann, Evelyn; Ermis, Ekin; Schmid, Ralph A.; Berezowska, Sabina (2021). Mutational profiles of primary pulmonary adenocarcinoma and paired brain metastases disclose the importance of KRAS mutations. European journal of cancer, 159, pp. 227-236. Elsevier 10.1016/j.ejca.2021.10.006
Losmanová, Tereza; Zens, Philipp; Scherz, Amina; Schmid, Ralph; Tschan, Mario P.; Berezowska, Sabina Anna (2021). Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy. Cells, 10(10) MDPI 10.3390/cells10102731
Rafiq, Sreoshee; McKenna, Sharon L; Muller, Sylviane; Tschan, Mario; Humbert, Magali (2021). Lysosomes in acute myeloid leukemia: potential therapeutic targets? Leukemia, 35(10), pp. 2759-2770. Springer Nature 10.1038/s41375-021-01388-x
Teodoro, Douglas; Ferdowsi, Sohrab; Borissov, Nikolay; Kashani, Elham; Vicente Alvarez, David; Copara, Jenny; Gouareb, Racha; Naderi, Nona; Amini, Poorya (2021). Information retrieval in an infodemic: the case of COVID-19 publications. Journal of medical internet research, 23(9), e30161. Centre of Global eHealth Innovation 10.2196/30161
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Humbert, Magali; Seiler, Kristina; Mosimann, Severin; Rentsch, Vreni; Sharma, Katyayani; Pandey, Amit Vikram; McKenna, Sharon L.; Tschan, Mario P. (2021). Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy. Cell death and differentiation, 28(8), pp. 2465-2481. Springer Nature 10.1038/s41418-021-00768-1
Niklaus, Nicolas J; Tokarchuk, Igor; Zbinden, Mara; Schläfli, Anna M; Maycotte, Paola; Tschan, Mario P. (2021). The Multifaceted Functions of Autophagy in Breast Cancer Development and Treatment. Cells, 10(6) MDPI 10.3390/cells10061447
Schläfli, Anna M; Tokarchuk, Igor; Parejo, Sarah; Jutzi, Susanne; Berezowska, Sabina; Engedal, Nikolai; Tschan, Mario P. (2021). ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells. Scientific reports, 11(1), p. 9011. Springer Nature 10.1038/s41598-021-87966-6
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Gruber, Thomas; Robatel, Steve; Kremenovic, Mirela; Bäriswyl, Lukas; Gertsch, Jürg; Schenk, Mirjam (2021). Cannabinoid Receptor Type-2 in B Cells Is Associated with Tumor Immunity in Melanoma. Cancers, 13(8) MDPI AG 10.3390/cancers13081934
Sadozai, Hassan; Acharjee, Animesh; Gruber, Thomas; Gloor, Beat; Karamitopoulou, Eva (2021). Pancreatic Cancers with High Grade Tumor Budding Exhibit Hallmarks of Diminished Anti-Tumor Immunity. Cancers, 13(5) MDPI AG 10.3390/cancers13051090
Sadozai, Hassan; Acharjee, Animesh; Eppenberger-Castori, Serenella; Gloor, Beat; Gruber, Thomas; Schenk, Mirjam; Karamitopoulou Diamantis, Evanthia (2021). Distinct Stromal and Immune Features Collectively Contribute to Long-Term Survival in Pancreatic Cancer. Frontiers in immunology, 12(643529), p. 643529. Frontiers Research Foundation 10.3389/fimmu.2021.643529
Seiler, Kristina; Tschan, Mario P. (2021). Autophagy and coronavirus infection - a Trojan horse or Achilles heel? Swiss medical weekly, 151(w20468), w20468. EMH Media 10.4414/smw.2021.20468
Tokarchuk, Igor; Janser, Félice A.; Schläfli, Anna M.; Pinto, Marta Teixeira; Humbert, Magali; Niklaus, Nicolas J.; Berezowska, Sabina; Langer, Rupert; Tschan, Mario P. (2021). Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability. Biochemical and biophysical research communications, 569, pp. 47-53. Elsevier 10.1016/j.bbrc.2021.06.082
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Kremenovic, M.; Schenk, Mirjam; Lee, D. J. (2020). Clinical and molecular insights into BCG immunotherapy for melanoma. Journal of internal medicine, 288(6), pp. 625-640. Wiley 10.1111/joim.13037
Gruber, Thomas; Kremenovic, Mirela; Sadozai, Hassan; Rombini, Nives; Baeriswyl, Lukas; Maibach, Fabienne; Modlin, Robert L; Gilliet, Michel; von Werdt, Diego; Hunger, Robert E.; Jafari, S. Morteza Seyed; Parisi, Giulia; Abril-Rodriguez, Gabriel; Ribas, Antoni; Schenk, Mirjam (2020). IL-32γ potentiates tumor immunity in melanoma. JCI insight, 5(18) JCI Insight 10.1172/jci.insight.138772
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Orfali, Nina; Shan-Krauer, Deborah; O'Donovan, Tracey R; Mongan, Nigel P; Gudas, Lorraine J; Cahill, Mary R; Tschan, Mario P.; McKenna, Sharon L (2020). Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells. Molecular oncology, 14(6), pp. 1297-1309. Wiley 10.1002/1878-0261.12614
Bonam, Srinivasa Reddy; Bayry, Jagadeesh; Tschan, Mario; Muller, Sylviane (2020). Progress and Challenges in The Use of MAP1LC3 as a Legitimate Marker for Measuring Dynamic Autophagy In Vivo. Cells, 9(5) MDPI 10.3390/cells9051321
Galván, José A.; Wiprächtiger, Julia; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Kröll, Dino; Seiler, Christian A.; Langer, Rupert (2020). Immunohistochemical analysis of the expression of cancer-associated fibroblast markers in esophageal cancer with and without neoadjuvant therapy. Virchows Archiv, 476(5), pp. 725-734. Springer 10.1007/s00428-019-02714-6
Humbert, Magali; Morán, María; de la Cruz-Ojeda, Patricia; Muntané, Jordi; Wiedmer, Tabea; Apostolova, Nadezda; McKenna, Sharon L; Velasco, Guillermo; Balduini, Walter; Eckhart, Leopold; Janji, Bassam; Sampaio-Marques, Belém; Ludovico, Paula; Žerovnik, Eva; Langer, Rupert; Perren, Aurel; Engedal, Nikolai; Tschan, Mario (2020). Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot. Biology, 9(3), pp. 1-24. MDPI 10.3390/biology9030059
Hewer, Ekkehard; Phour, Jaison; Gutt-Will, Marielena; Schucht, Philippe; Dettmer, Matthias S; Vassella, Erik (2020). TERT Promoter Mutation Analysis to Distinguish Glioma From Gliosis. Journal of neuropathology and experimental neurology, 79(4), pp. 430-436. Oxford University Press 10.1093/jnen/nlaa004
Kremenovic, Mirela; Rombini, Nives; Chan, Alfred A.; Gruber, Thomas; Bäriswyl, Lukas; Lee, Delphine J.; Schenk, Mirjam (2020). Characterization of a Myeloid Activation Signature that Correlates with Survival in Melanoma Patients. Cancers, 12(6), p. 1431. MDPI AG 10.3390/cancers12061431
Bockstahler, Mariella; Fischer, Andrea; Goetzke, Carl Christoph; Neumaier, Hannah Louise; Sauter, Martina; Kespohl, Meike; Müller, Anna-Maria; Meckes, Christin; Salbach, Christian; Schenk, Mirjam; Heuser, Arnd; Landmesser, Ulf; Weiner, January; Meder, Benjamin; Lehmann, Lorenz; Kratzer, Adelheid; Klingel, Karin; Katus, Hugo A.; Kaya, Ziya and Beling, Antje (2020). Heart-Specific Immune Responses in an Animal Model of Autoimmune-Related Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation. Circulation, 141(23), pp. 1885-1902. American Heart Association 10.1161/circulationaha.119.043171
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Maibach, Fabienne; Sadozai, Hassan; Jafari, S. Morteza Seyed; Hunger, Robert E.; Schenk, Mirjam (2020). Tumor-Infiltrating Lymphocytes and Their Prognostic Value in Cutaneous Melanoma. Frontiers in immunology, 11(2105), p. 2105. Frontiers Research Foundation 10.3389/fimmu.2020.02105
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Gavini, Jacopo; Dommann, Noëlle; Jakob, Manuel O.; Keogh, Adrian; Bouchez, Laure C; Karkampouna, Sofia; Kruithof-de Julio, Marianna; Medova, Michaela; Zimmer, Yitzhak; Schläfli, Anna M; Tschan, Mario P.; Candinas, Daniel; Stroka, Deborah; Banz, Vanessa (2019). Verteporfin-induced lysosomal compartment dysregulation potentiates the effect of sorafenib in hepatocellular carcinoma. Cell death & disease, 10(10), p. 749. Springer Nature 10.1038/s41419-019-1989-z
Adams, Olivia; Janser, Félice A.; Dislich, Bastian; Berezowska, Sabina; Humbert, Magali; Seiler, Christian A.; Kröll, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario P.; Langer, Rupert (2019). Correction: A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE, 14(10), e0224832. Public Library of Science 10.1371/journal.pone.0224832
Djavaheri-Mergny, Mojgan; Giuriato, Sylvie; Tschan, Mario; Humbert, Magali (2019). Therapeutic Modulation of Autophagy in Leukaemia and Lymphoma. Cells, 8(2) MDPI 10.3390/cells8020103
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Parejo, Sarah; Tschan, Mario; Muraro, Manuele G; Garattini, Enrico; Spagnoli, Giulio C; Schläfli, Anna M (2019). Assessing Autophagy During Retinoid Treatment of Breast Cancer Cells. In: Ray, Swapan K. (ed.) Retinoid and Rexinoid Signaling. Methods in molecular biology: Vol. 2019 (pp. 237-256). Springer 10.1007/978-1-4939-9585-1_17
Meyer, Sara N.; Galván, José A.; Zahnd, Stefan; Sokol, Lena; Dawson, Heather; Lugli, Alessandro; Zlobec, Inti (2019). Co-expression of cytokeratin and vimentin in colorectal cancer highlights a subset of tumor buds and an atypical cancer-associated stroma. Human pathology, 87, pp. 18-27. Elsevier 10.1016/j.humpath.2019.02.002
Janser, Ariane F.; Tschan, Mario P.; Langer, Rupert (2019). The role of autophagy in HER2-targeted therapy. Swiss medical weekly, 149(149), w20138. EMH Media 10.4414/smw.2019.20138
Janser, Félice A.; Ney, Patricia; Teixeira Pinto, Marta; Langer, Rupert; Tschan, Mario P. (2019). The Chick Chorioallantoic Membrane (CAM) Assay as a Three-dimensional Model to Study Autophagy in Cancer Cells. Bio-protocol, 9(13) bio-protocol 10.21769/BioProtoc.3290
Janser, Félice A.; Adams, Olivia Joan; Bütler, Vanessa; Bill, Anna Magdalena; Dislich, Bastian; Seiler, Christian A.; Kröll, Dino; Langer, Rupert; Tschan, Mario (2018). Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells. International journal of molecular sciences, 19(10) MDPI 10.3390/ijms19103069
Graule, Janina; Uth-Gottardi, Kristin; Fischer, Elia Luca; Centeno Ramos, Irene; Galván Hernández, José Alberto; Eichmann, Micha David; Rau, Tilman; Langer, Rupert; Dawson, Heather; Nitsche, Ulrich; Traeger, Peter; Berger, Martin Dave; Schnüriger, Beat; Hädrich, Marion; Studer, Peter; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2018). CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway. Clinical epigenetics, 10(1), p. 120. Springer 10.1186/s13148-018-0548-2
Niklaus, Nicolas Jan; Humbert, Magali; Tschan, Mario (2018). Cisplatin sensitivity in breast cancer cells is associated with particular DMTF1 splice variant expression. Biochemical and biophysical research communications, 503(4), pp. 2800-2806. Academic Press 10.1016/j.bbrc.2018.08.042
Koeck, Ivonne; Hashemi Gheinani, Ali; Baumgartner, Ulrich; Vassella, Erik; Bruggmann, Rémy; Burkhard, Fiona C.; Monastyrskaya, Katia (2018). Tumor Necrosis Factor-α Initiates miRNA-mRNA Signaling Cascades in Obstruction-Induced Bladder Dysfunction. The American journal of pathology, 188(8), pp. 1847-1864. Elsevier 10.1016/j.ajpath.2018.05.008
Keegan, Caroline; Krutzik, Stephan; Schenk, Mirjam; Scumpia, Philip O; Lu, Jing; Pang, Yan Ling Joy; Russell, Brandon S; Lim, Kok Seong; Shell, Scarlet; Prestwich, Erin; Su, Dan; Elashoff, David; Hershberg, Robert M; Bloom, Barry R; Belisle, John T; Fortune, Sarah; Dedon, Peter C; Pellegrini, Matteo; Modlin, Robert L (2018). Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. Journal of immunology, 200(9), pp. 3244-3258. American Association of Immunologists 10.4049/jimmunol.1701733
Hashemi Gheinani, Ali; Vögeli, Mike; Baumgartner, Ulrich; Vassella, Erik; Draeger, Annette; Burkhard, Fiona C.; Monastyrskaya-Stäuber, Katia (2018). Improved isolation strategies to increase the yield and purity of human urinary exosomes for biomarker discovery. Scientific Reports, 8(1), p. 3945. Nature Publishing Group 10.1038/s41598-018-22142-x
Baumgartner, Ulrich; Berger, Fabienne; Hashemi Gheinani, Ali; Burgener, Sabrina Sofia; Monastyrskaya-Stäuber, Katia; Vassella, Erik (2018). miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer. Molecular cancer, 17(1), p. 44. BioMed Central 10.1186/s12943-018-0781-5
Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795
Adams, Olivia; Janser, Félice A.; Dislich, Bastian; Berezowska, Sabina; Humbert, Magali; Seiler, Christian A.; Kroell, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario P.; Langer, Rupert (2018). A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE, 13(6), e0197610. Public Library of Science 10.1371/journal.pone.0197610
Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281
Hashemi Gheinani, Ali; Köck, Ivonne; Vasquez, Evalynn; Baumgartner, Ulrich; Bigger-Allen, Alexander; Sack, Bryan S; Burkhard, Fiona C.; Adam, Rosalyn M; Monastyrskaya, Katia (2018). Concordant miRNA and mRNA expression profiles in humans and mice with bladder outlet obstruction. American journal of clinical and experimental urology, 6(6), pp. 219-233. e-Century Publishing
Humbert, Magali; Federzoni, Elena; Tschan, Mario (2017). Distinct TP73-DAPK2-ATG5 pathway involvement in ATO-mediated cell death versus ATRA-mediated autophagy responses in APL. Journal of leukocyte biology, 102(6), pp. 1357-1370. Society for Leukocyte Biology 10.1189/jlb.1A0317-132R
Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136
Schläfli, Anna; Isakson, Pauline; Garattini, E; Simonsen, Anne; Tschan, Mario (2017). The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. Scientific Reports, 7(1), p. 12980. Nature Publishing Group 10.1038/s41598-017-12734-4
Broglie, Martina A; Stoeckli, Sandro J; Sauter, Rafael; Pasche, Philippe; Reinhard, Antoine; de Leval, Laurence; Huber, Gerhard F; Pezier, Thomas F; Soltermann, Alex; Giger, Roland; Arnold, Andreas; Dettmer, Matthias; Arnoux, Andre; Müller, Martin; Spreitzer, Stefan; Lang, Florian; Lutchmaya, Mathieu; Stauffer, Edouard; Espeli, Vittoria; Martucci, Francesco; ... (2017). Impact of human papillomavirus on outcome in patients with oropharyngeal cancer treated with primary surgery. Head & neck - journal for the sciences and specialties of the head and neck, 39(10), pp. 2004-2015. J. Wiley 10.1002/hed.24865
Mele, Valentina; Sokol, Lena; Kölzer, Viktor; Pfaff, Dennis; Muraro, Manuele Giuseppe; Keller, Irene; Zahnd, Stefan Patrick; Centeno Ramos, Irene; Terracciano, Luigi Maria; Dawson, Heather; Zlobec, Inti; Iezzi, Giandomenica; Lugli, Alessandro (2017). The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer. OncoTarget, 8(41), pp. 70617-70629. Impact Journals LLC 10.18632/oncotarget.19904
Amer, Wafa; Toth, Csaba; Vassella, Erik; Meinrath, Jeannine; Koitzsch, Ulrike; Arens, Anne; Huang, Jia; Eischeid, Hannah; Adam, Alexander; Buettner, Reinhard; Scheel, Andreas; Schaefer, Stephan C; Odenthal, Margarete (2017). Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome. Scientific Reports, 7(1), p. 11069. Nature Publishing Group 10.1038/s41598-017-11345-3
Niklaus, Monique; Adams, Olivia Joan; Berezowska, Sabina Anna; Zlobec, Inti; Graber, Franziska; Slotta-Huspenina, Julia; Nitsche, Ulrich; Rosenberg, Robert; Tschan, Mario; Langer, Rupert (2017). Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer. OncoTarget, 8(33), pp. 54604-54615. Impact Journals LLC 10.18632/oncotarget.17554
Karamitopoulou, Evanthia; Haemmig, Stefan; Baumgartner, Ulrich; Schlup, Cornelia; Wartenberg, Martin; Vassella, Erik (2017). MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. Modern pathology, 30(8), pp. 1116-1125. Nature Publishing Group 10.1038/modpathol.2017.35
Bakula, Daniela; Müller, Amelie J; Zuleger, Theresia; Takacs, Zsuzsanna; Franz-Wachtel, Mirita; Thost, Ann-Katrin; Brigger, Daniel; Tschan, Mario; Frickey, Tancred; Robenek, Horst; Macek, Boris; Proikas-Cezanne, Tassula (2017). WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nature communications, 8(15637), p. 15637. Nature Publishing Group 10.1038/ncomms15637
Rothschild, Sacha; Gautschi, Oliver; Batliner, Jasmin; Gugger, Mathias; Fey, Martin; Tschan, Mario (2017). MicroRNA-106a targets autophagy and enhances sensitivity of lung cancer cells to Src inhibitors. Lung cancer, 107, pp. 73-83. Elsevier 10.1016/j.lungcan.2016.06.004
Haimovici, Aladin; Humbert, Magali; Federzoni, Elena A; Shan-Krauer, Deborah; Brunner, Thomas; Frese, Steffen; Kaufmann, Thomas; Torbett, Bruce E; Tschan, Mario (2017). PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell death and differentiation, 24(5), pp. 866-877. Nature Publishing Group 10.1038/cdd.2017.40
Dislich, Bastian; Stein, Alexandra Vanessa; Seiler, Christian A.; Kröll, Dino; Berezowska, Sabina Anna; Zlobec, Inti; Galván Hernández, José Alberto; Slotta-Huspenina, Julia; Walch, Axel; Langer, Rupert (2017). Expression patterns of programmed death-ligand 1 in esophageal adenocarcinomas: comparison between primary tumors and metastases. Cancer immunology, immunotherapy, 66(6), pp. 777-786. Springer 10.1007/s00262-017-1982-2
Sadozai, Hassan Ahmed; Gruber, Thomas; Schenk, Mirjam (2017). Induction of effective anti-tumour immunity by targeting dendritic cells in vivo. Madridge Journal of Vaccines, 1(1), e1-e4. Madridge Publishers
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Garcia-Carbonero, R; Sorbye, H; Baudin, E; Raymond, E; Wiedenmann, B; Niederle, B; Sedlackova, E; Toumpanakis, C; Anlauf, M; Cwikla, J B; Caplin, M; O'Toole, D; Perren, Aurel (2017). ENETS Consensus Guidelines for High-Grade Gastroenteropancreatic Neuroendocrine Tumors and Neuroendocrine Carcinomas. Neuroendocrinology, 103(2), pp. 186-194. Karger 10.1159/000443172
Dislich, Bastian; Stein, Alexandra Vanessa; Galván Hernández, José Alberto; Berezowska, Sabina Anna; Seiler, Christian A.; Kröll, Dino; Langer, Rupert (2017). P2.04-026 Expression Patterns of PD-L1 in Esophageal Adenocarcinomas: Comparison between Primary Tumors and Metastases. Journal of thoracic oncology, 12(1S), s1012-s1012. Elsevier 10.1016/j.jtho.2016.11.1406
Malla, Bijaya; Zaugg, Kathrin; Vassella, Erik; Aebersold, Daniel; Dal Pra, Alan (2017). Exosomes and Exosomal MicroRNAs in Prostate Cancer Radiation Therapy. International journal of radiation oncology, biology, physics, 98(5), pp. 982-995. Elsevier 10.1016/j.ijrobp.2017.03.031
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Adams, Olivia Joan; Dislich, Bastian; Berezowska, Sabina Anna; Schläfli, Anna; Seiler, Christian A.; Kröll, Dino; Tschan, Mario; Langer, Rupert (2016). Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas. OncoTarget, 7(26), pp. 39241-39255. Impact Journals LLC 10.18632/oncotarget.9649
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Schwetz, Verena; Horvath, Karl; Kump, Patrizia; Lackner, Carolin; Perren, Aurel; Forrer, Flavio; Pieber, Thomas R; Treiber, Gerlies; Sourij, Harald; Mader, Julia K (2016). Successful Medical Treatment of Adult Nesidioblastosis With Pasireotide over 3 Years: A Case Report. Medicine, 95(14), e3272. Lippincott Williams & Wilkins 10.1097/MD.0000000000003272
Weber, Martin R; Zuka, Masahiko; Lorger, Mihaela; Tschan, Mario; Torbett, Bruce E; Zijlstra, Andries; Quigley, James P; Staflin, Karin; Eliceiri, Brian P; Krueger, Joseph S; Marchese, Patrizia; Ruggeri, Zaverio M; Felding, Brunhilde H (2016). Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream. Thrombosis research, 140(Suppl1), S27-36. Elsevier 10.1016/S0049-3848(16)30095-0
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Wampfler, Julian; Federzoni, Elena; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2016). The RNA binding proteins RBM38 and DND1 are repressed in AML and have a novel function in APL differentiation. Leukemia research, 41, pp. 96-102. Elsevier 10.1016/j.leukres.2015.12.006
Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356
Kölzer, Viktor; Zlobec, Inti; Lugli, Alessandro (2016). Tumor budding in colorectal cancer—ready for diagnostic practice? Human pathology, 47(1), pp. 4-19. Elsevier 10.1016/j.humpath.2015.08.007
Mager, Lukas; Wasmer, Marie-Hélène; Rau, Tilman; Krebs, Philippe (2016). Cytokine-Induced Modulation of Colorectal Cancer. Frontiers in oncology, 6(96), p. 96. Frontiers Research Foundation 10.3389/fonc.2016.00096
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Tschan, Mario P.; Federzoni, Elena A.; Haimovici, Aladin; Britschgi, Christian; Moser, Bettina A.; Jin, Jing; Reddy, Venkateshwar A.; Sheeter, Dennis A.; Fischer, Kimberlee M.; Sun, Peiqing; Torbett, Bruce E. (2015). Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation. Biochimica et biophysica acta - gene regulatory mechanisms, 1849(9), pp. 1198-1208. Elsevier 10.1016/j.bbagrm.2015.07.009
Wampfler, Julian; Federzoni, Elena; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2015). Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells. Journal of leukocyte biology, 98(3), pp. 357-363. Society for Leukocyte Biology 10.1189/jlb.1AB0514-258R
Orfali, Nina; O'Donovan, Tracey R; Nyhan, Michelle J; Britschgi, Adrian; Tschan, Mario; Cahill, Mary R; Mongan, Nigel P; Gudas, Lorraine J; McKenna, Sharon L (2015). Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation. Experimental hematology, 43(9), 781-793.e2. Elsevier 10.1016/j.exphem.2015.04.012
Delgado Tascón, Julia; Adrian, Jonas; Kopp, Kathrin; Scholz, Philipp; Tschan, Mario; Kuespert, Katharina; Hauck, Christof R (2015). The granulocyte orphan receptor CEACAM4 is able to trigger phagocytosis of bacteria. Journal of leukocyte biology, 97(3), pp. 521-531. Society for Leukocyte Biology 10.1189/jlb.2AB0813-449RR
Federzoni, Elena; Gloor, Severin; Jin, Jing; Krauer, Deborah; Fey, Martin; Torbett, Bruce E; Tschan, Mario (2015). Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells. Leukemia research reports, 4(1), pp. 32-35. Elsevier 10.1016/j.lrr.2015.04.002
Brockmann, Anette; Bluwstein, A; Kögel, A; May, S; Marx, A; Tschan, Mario; Brunner, Thomas (2015). Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation. Cell death & disease, 6(6), e1778-e1778. Nature Publishing Group 10.1038/cddis.2015.137
Schläfli, Anna; Berezowska, Sabina Anna; Adams, Olivia Joan; Langer, Rupert; Tschan, Mario (2015). Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry. European journal of histochemistry, 59(2), p. 2481. Luigi Ponzio 10.4081/ejh.2015.2481
Brigger, D.; Schläfli, Anna; Garattini, E.; Tschan, M. P. (2015). Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity. Cell death & disease, 6(e1861), e1861. Nature Publishing Group 10.1038/cddis.2015.236
Geering, Barbara; Zokouri, Zina; Hürlemann, Samuel; Gerrits, Bertran; Ausländer, David; Britschgi, Adrian; Tschan, Mario; Simon, Hans-Uwe; Fussenegger, Martin (2015). Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Molecular and cellular biology, 36(1), pp. 132-143. American Society for Microbiology 10.1128/MCB.00515-15
Haimovici, Aladin; Brigger, Daniel; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2014). Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leukemia research, 38(9), pp. 1041-1047. Elsevier 10.1016/j.leukres.2014.06.010
Helbling, Melina; Lukesch, Anne Carolin; Haimovici, Aladin; Karamitopoulou, Evanthia; Berger, Martin Dave; Hädrich, Marion; Mallaev, Makhmud; Schnüriger, Beat; Kölzer, Viktor; Dawson, Heather; Borner, Markus; Langer, Rupert; Rosenberg, Robert; Nitsche, Ulrich; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2014). Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients. OncoTarget, 5(13), pp. 4671-4682. Impact Journals LLC
Pfisterer, Simon G; Bakula, Daniela; Frickey, Tancred; Cezanne, Alice; Brigger, Daniel; Tschan, Mario; Robenek, Horst; Proikas-Cezanne, Tassula (2014). Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells. Journal of lipid research, 55(7), pp. 1267-1278. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M046359
Stutz, Emanuel; Gautschi, Oliver; Fey, Martin F.; Gugger, Mathias; Tschan, Mario; Rothschild, Sacha I. (2014). Crizotinib inhibits migration and expression of ID1 in MET-positive lung cancer cells: implications for MET targeting in oncology. Future oncology, 10(2), pp. 211-217. Future Medicine Ltd. 10.2217/fon.13.179
Federzoni, Elena; Humbert, Magali; Torbett, Bruce E; Behre, Gerhard; Fey, Martin; Tschan, Mario (2014). CEBPA-dependent HK3 and KLF5 expression in primary AML and during AML differentiation. Scientific Reports, 4(1), p. 4261. Nature Publishing Group 10.1038/srep04261
Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899
Brigger, Daniel; Proikas-Cezanne, T; Tschan, Mario (2014). WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells. Cell death & disease, 5(e1315), e1315. Nature Publishing Group 10.1038/cddis.2014.261
Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245
Portmann, Simone; Fahrner, René; Lechleiter, Antje; Keogh, Adrian; Overney, Sarah; Lämmle, Alexander; Mikami, Kei; Montani, Matteo; Tschan, Mario; Candinas, Daniel; Keogh-Stroka, Deborah M. (2013). Antitumor effect of SIRT1 inhibition in human HCC tumor models in vitro and in vivo. Molecular cancer therapeutics, 12(4), pp. 499-508. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-12-0700
Humbert, Magali; Medova, Michaela; Aebersold, Daniel; Blaukat, Andree; Bladt, Friedhelm; Fey, Martin; Zimmer, Yitzhak; Tschan, Mario P. (2013). Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells. Biochemical and biophysical research communications, 431(2), pp. 264-269. Academic Press 10.1016/j.bbrc.2012.12.120
Federzoni, Elena A.; Humbert, Magali; Valk, Peter J. M.; Behre, Gerhard; Leibundgut, Elisabeth O.; Torbett, Bruce E; Fey, Martin F.; Tschan, Mario (2013). The actin-binding protein CORO1A is a novel PU.1 (SPI1)- and CEBPA-regulated gene with significantly lower expression in APL and CEBPA-mutated AML patients. British journal of haematology, 160(6), pp. 855-859. Oxford: Wiley-Blackwell 10.1111/bjh.12170
He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104
Brigger, Daniel; Torbett, Bruce E.; Chen, Joy; Fey, Martin; Tschan, Mario (2013). Inhibition of GATE-16 attenuates ATRA-induced neutrophil differentiation of APL cells and interferes with autophagosome formation. Biochemical and biophysical research communications, 438(2), pp. 283-288. Academic Press 10.1016/j.bbrc.2013.07.056
Dettmer, Matthias; Hench, Juergen; Pang, Brendan; Willi, Niels; Cathomas, Gieri (2012). Rhabdoid large cell carcinoma of lung, with illustrative immunohistochemical and molecular findings. Applied immunohistochemistry & molecular morphology, 20(3), pp. 208-213. LIPPINCOTT WILLIAMS & WILKINS 10.1097/PAI.0b013e31823d8121
Dettmer, Matthias; Kim, Tae Eun; Jung, Chan Kwon; Jung, Eun Sun; Lee, Kyo Young; Kang, Chang Suk (2011). Thyroid transcription factor-1 expression in colorectal adenocarcinomas. Pathology, research and practice, 207(11), pp. 686-690. Elsevier 10.1016/j.prp.2011.08.009
Dettmer, Matthias; Itin, Peter; Miny, Peter; Gandhi, Manoj; Cathomas, Gieri; Willi, Niels (2011). Giant ectopic liver, hepatocellular carcinoma and pachydermia-a rare genetic syndrome? Diagnostic pathology, 6(75), p. 75. BioMed Central 10.1186/1746-1596-6-75
Waser, Beatrice; Beetschen, Karin; Pellegata, Natalia S; Reubi, J.C. (2011). Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy. Neuroendocrinology, 94(4), pp. 291-301. Basel: Karger 10.1159/000330447
Erchegyi, Judit; Cescato, Renzo; Grace, Christy Rani R; Waser, Beatrice; Piccand, Véronique; Hoyer, Daniel; Riek, Roland; Rivier, Jean E; Reubi, Jean-Claude (2009). Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues. Journal of medicinal chemistry, 52(9), pp. 2733-46. Easton, Pa.: American Chemical Society 10.1021/jm801314f
Van Rechem, C.; Rood, B. R.; Touka, M.; Pinte, S.; Jenal, Mathias; Guerardel, C.; Ramsey, K.; Monte, D.; Begue, A.; Tschan, Mario; Stephan, D. A.; Leprince, D. (2009). Scavenger Chemokine (CXC Motif) Receptor 7 (CXCR7) Is a Direct Target Gene of HIC1 (Hypermethylated in Cancer 1). Journal of biological chemistry, 284(31), pp. 20927-20935. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M109.022350
Erchegyi, Judit; Grace, Christy Rani R; Samant, Manoj; Cescato, Renzo; Piccand, Veronique; Riek, Roland; Reubi, Jean Claude; Rivier, Jean E (2008). Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity. Journal of medicinal chemistry, 51(9), pp. 2668-75. Easton, Pa.: American Chemical Society 10.1021/jm701444y
Grace, Christy Rani R; Erchegyi, Judit; Samant, Manoj; Cescato, Renzo; Piccand, Veronique; Riek, Roland; Reubi, Jean Claude; Rivier, Jean E (2008). Ring size in octreotide amide modulates differently agonist versus antagonist binding affinity and selectivity. Journal of medicinal chemistry, 51(9), pp. 2676-81. Easton, Pa.: American Chemical Society 10.1021/jm701445q
D'Addona, Debora; Carotenuto, Alfonso; Novellino, Ettore; Piccand, Véronique; Reubi, Jean Claude; Di Cianni, Alessandra; Gori, Francesca; Papini, Anna Maria; Ginanneschi, Mauro (2008). Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships. Journal of medicinal chemistry, 51(3), pp. 512-20. Easton, Pa.: American Chemical Society 10.1021/jm070886i
Cescato, Renzo; Maina, Theodosia; Nock, Berthold; Nikolopoulou, Anastasia; Charalambidis, David; Piccand, Véronique; Reubi, Jean Claude (2008). Bombesin receptor antagonists may be preferable to agonists for tumor targeting. Journal of nuclear medicine, 49(2), pp. 318-26. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.107.045054
Cescato, Renzo; Erchegyi, Judith; Waser, Beatrice; Piccand, Véronique; Maecke, Helmut R; Rivier, Jean E; Reubi, Jean Claude (2008). Design and in vitro characterization of highly sst2-selective somatostatin antagonists suitable for radiotargeting. Journal of medicinal chemistry, 51(13), pp. 4030-7. Easton, Pa.: American Chemical Society 10.1021/jm701618q
Blancafort, P.; Tschan, Mario; Bergquist, S.; Guthy, D.; Brachat, A.; Sheeter, D. A.; Torbett, B. E.; Erdmann, D.; Barbas, C. F. (2008). Modulation of drug resistance by artificial transcription factors. Molecular cancer therapeutics, 7(3), pp. 688-697. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-07-0381
Fang, J.; Menon, M.; Zhang, D.; Torbett, B.; Oxburgh, L.; Tschan, Mario; Houde, E.; Wojchowski, D. M. (2008). Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2. Blood, 112(3), pp. 886-890. American Society of Hematology 10.1182/blood-2008-02-138909
Swan, C H; Bühler, B; Steinberger, P; Tschan, Mario; Barbas, C F; Torbett, B E (2007). T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery. Gene therapy, 14(7), p. 626. Nature Publishing Group 10.1038/sj.gt.3302902
Tschan, Mario; Fischer, K. M.; Fung, V. S.; Pirnia Borner, Farzaneh; Borner, Markus; Fey, Martin; Tobler, Andreas; Torbett, B. E. (2003). Alternative Splicing of the Human Cyclin D-binding Myb-like Protein (hDMP1) Yields a Truncated Protein Isoform That Alters Macrophage Differentiation Patterns. Journal of biological chemistry, 278(44), pp. 42750-42760. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M307067200
Novak, Urban; Grob, T. J.; Baskaynak, G.; Peters, U. R.; Aebi, Stefan; Zwahlen, D.; Tschan, Mario; Kreuzer, K.-A.; Oppliger Leibundgut, Elisabeth; Cajot, J.-F.; Tobler, Andreas; Fey, Martin (2001). Overexpression of the p73 gene is a novel finding in high-risk B-cell chronic lymphocytic leukemia. Annals of oncology, 12(7), pp. 981-986. Oxford University Press 10.1023/A:1011153206003
Tschan, Mario; Grob, Tobias J.; Peters, Uwe R.; Laurenzi, Vincenzo De; Huegli, B.; Kreuzer, K.-A.; Schmidt, C.A.; Melino, Gerry; Fey, Martin F.; Tobler, Andreas; Cajot, Jean-François (2000). Enhanced p73 Expression during Differentiation and Complex p73 Isoforms in Myeloid Leukemia. Biochemical and biophysical research communications, 277(1), pp. 62-65. Academic Press 10.1006/bbrc.2000.3627
Zwahlen, Daniel; Tschan, Mario; Grob, Tobias J.; Peters, Uwe R.; Fink, Daniel; Haenggi, Willy; Altermatt, Hans J.; Cajot, Jean-François; Tobler, Andreas; Fey, Martin F.; Aebi, Stefan (2000). Differential expression of p73 splice variants and protein in benign and malignant ovarian tumours. International journal of cancer, 88(1), pp. 66-70. Wiley-Blackwell 10.1002/1097-0215(20001001)88:1<66::AID-IJC10>3.0.CO;2-Y
Tschan, Mario; Peters, U. R.; Cajot, J. F.; Betticher, D. C.; Fey, M. F.; Tobler, A. (1999). The cyclin-dependent kinase inhibitors p18INK4c and p19INK4d are highly expressed in CD34+ progenitor and acute myeloid leukaemic cells but not in normal differentiated myeloid cells. British journal of haematology, 106(3), pp. 644-651. Wiley-Blackwell 10.1046/j.1365-2141.1999.01617.x
